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Search of human proteins with 217330634
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217330634 serine/threonine kinase 36 [Homo sapiens]
(1315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217330634 serine/threonine kinase 36 [Homo sapiens] 2604 0.0
gi|62865643 aurora kinase C isoform 3 [Homo sapiens] 171 3e-42
gi|62865641 aurora kinase C isoform 2 [Homo sapiens] 171 3e-42
gi|62865639 aurora kinase C isoform 1 [Homo sapiens] 171 3e-42
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens] 167 6e-41
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens] 167 6e-41
gi|150456432 unc-51-like kinase 3 [Homo sapiens] 167 6e-41
gi|217330559 unc-51-like kinase 2 [Homo sapiens] 166 1e-40
gi|217330557 unc-51-like kinase 2 [Homo sapiens] 166 1e-40
gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [H... 165 2e-40
gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4 [... 165 2e-40
gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3 [... 165 2e-40
gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2 [... 165 2e-40
gi|62241015 AKT1 kinase [Homo sapiens] 164 4e-40
gi|62241013 AKT1 kinase [Homo sapiens] 164 4e-40
gi|62241011 AKT1 kinase [Homo sapiens] 164 4e-40
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 164 5e-40
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 164 5e-40
gi|4502023 AKT2 kinase [Homo sapiens] 164 7e-40
gi|41872673 NIMA-related kinase 1 [Homo sapiens] 160 6e-39
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 160 6e-39
gi|23510391 NIMA-related kinase 3 isoform a [Homo sapiens] 160 7e-39
gi|23510393 NIMA-related kinase 3 isoform a [Homo sapiens] 160 7e-39
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 159 1e-38
gi|21361358 serine/threonine kinase 25 [Homo sapiens] 158 4e-38
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 157 5e-38
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 157 5e-38
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 157 5e-38
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens] 157 5e-38
gi|38327564 serine/threonine protein kinase 6 [Homo sapiens] 157 5e-38
>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
Length = 1315
Score = 2604 bits (6750), Expect = 0.0
Identities = 1315/1315 (100%), Positives = 1315/1315 (100%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH
Sbjct: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR
Sbjct: 61 PNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
Query: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT
Sbjct: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
Query: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR
Sbjct: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
Query: 241 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR 300
QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR
Sbjct: 241 QRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSR 300
Query: 301 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS 360
ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS
Sbjct: 301 ILTQAYKRMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILAS 360
Query: 361 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW 420
ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW
Sbjct: 361 ELKSSWAKSGTGEVPSAPRENRTTPDCERAFPEERPEVLGQRSTDVVDLENEEPDSDNEW 420
Query: 421 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS 480
QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS
Sbjct: 421 QHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLS 480
Query: 481 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA 540
SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA
Sbjct: 481 SLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFA 540
Query: 541 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN 600
CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN
Sbjct: 541 CTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSEQTLRRDSLMCFTVLCEAMDGN 600
Query: 601 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS 660
SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS
Sbjct: 601 SRAISKAFYSSLLTTQQVVLDGLLHGLTVPQLPVHTPQGAPQVSQPLREQSEDIPGAISS 660
Query: 661 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS 720
ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS
Sbjct: 661 ALAAICTAPVGLPDCWDAKEQVCWHLANQLTEDSSQLRPSLISGLQHPILCLHLLKVLYS 720
Query: 721 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM 780
CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM
Sbjct: 721 CCLVSEGLCRLLGQEPLALESLFMLIQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGM 780
Query: 781 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL 840
EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL
Sbjct: 781 EKLGSDVATLFTHSHVVSLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRL 840
Query: 841 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG 900
TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG
Sbjct: 841 TPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLWHRFSMVLRLPEEASAQEG 900
Query: 901 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC 960
ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC
Sbjct: 901 ELSLSSPPSPEPDWTLISPQGMAALLSLAMATFTQEPQLCLSCLSQHGSILMSILKHLLC 960
Query: 961 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV 1020
PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV
Sbjct: 961 PSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQV 1020
Query: 1021 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD 1080
CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD
Sbjct: 1021 CCYHLPLMQVELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSD 1080
Query: 1081 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS 1140
LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS
Sbjct: 1081 LLSLLAHTARVLSPSHLSFIQELLAGSDESYRPLRSLLGHPENSVRAHTYRLLGHLLQHS 1140
Query: 1141 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL 1200
MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL
Sbjct: 1141 MALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQL 1200
Query: 1201 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1260
LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL
Sbjct: 1201 LGDPQAGIRRNVASALGNLGPEGLGEELLQCEVPQRLLEMACGDPQPNVKEAALIALRSL 1260
Query: 1261 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM 1315
QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM
Sbjct: 1261 QQEPGIHQVLVSLGASEKLSLLSLGNQSLPHSSPRPASAKHCRKLIHLLRPAHSM 1315
>gi|62865643 aurora kinase C isoform 3 [Homo sapiens]
Length = 275
Score = 171 bits (434), Expect = 3e-42
Identities = 95/266 (35%), Positives = 153/266 (57%), Gaps = 4/266 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
++ + + +G+G FG VY R K S +VALK + K ++ L + L+REIEI L+
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 60 HPNIVHMLDSFETDKEVVVVTDYA-EGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + + F + V ++ +YA GEL++ L+ KL E + I +L AL Y H
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 125
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+++HRD+KP+N+LL G +K+ DFG++ + T ++ ++ GT Y+ PE++E R YD
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRTYD 183
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLW +G + YEL VG PPF + S + ILK VR+P ++ ++ + LL
Sbjct: 184 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 243
Query: 239 PRQRLSWPDLLYHPFIAGHVTIITEP 264
P +RL +L HP++ H + P
Sbjct: 244 PLERLPLAQILKHPWVQAHSRRVLPP 269
>gi|62865641 aurora kinase C isoform 2 [Homo sapiens]
Length = 290
Score = 171 bits (434), Expect = 3e-42
Identities = 95/266 (35%), Positives = 153/266 (57%), Gaps = 4/266 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
++ + + +G+G FG VY R K S +VALK + K ++ L + L+REIEI L+
Sbjct: 21 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 80
Query: 60 HPNIVHMLDSFETDKEVVVVTDYA-EGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + + F + V ++ +YA GEL++ L+ KL E + I +L AL Y H
Sbjct: 81 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 140
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+++HRD+KP+N+LL G +K+ DFG++ + T ++ ++ GT Y+ PE++E R YD
Sbjct: 141 KKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRTYD 198
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLW +G + YEL VG PPF + S + ILK VR+P ++ ++ + LL
Sbjct: 199 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 258
Query: 239 PRQRLSWPDLLYHPFIAGHVTIITEP 264
P +RL +L HP++ H + P
Sbjct: 259 PLERLPLAQILKHPWVQAHSRRVLPP 284
>gi|62865639 aurora kinase C isoform 1 [Homo sapiens]
Length = 309
Score = 171 bits (434), Expect = 3e-42
Identities = 95/266 (35%), Positives = 153/266 (57%), Gaps = 4/266 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
++ + + +G+G FG VY R K S +VALK + K ++ L + L+REIEI L+
Sbjct: 40 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99
Query: 60 HPNIVHMLDSFETDKEVVVVTDYA-EGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + + F + V ++ +YA GEL++ L+ KL E + I +L AL Y H
Sbjct: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 159
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+++HRD+KP+N+LL G +K+ DFG++ + T ++ ++ GT Y+ PE++E R YD
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRRKTMCGTLDYLPPEMIEGRTYD 217
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLW +G + YEL VG PPF + S + ILK VR+P ++ ++ + LL
Sbjct: 218 EKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQ 277
Query: 239 PRQRLSWPDLLYHPFIAGHVTIITEP 264
P +RL +L HP++ H + P
Sbjct: 278 PLERLPLAQILKHPWVQAHSRRVLPP 303
>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
Length = 479
Score = 167 bits (423), Expect = 6e-41
Identities = 92/263 (34%), Positives = 152/263 (57%), Gaps = 7/263 (2%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M + L+++G+G+FG+V R K S + A+K + K + ++ E+ + E +++ R
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + SF+T + V +Y G ELF L + ED+ + A++VSAL YLHS
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+I++RD+K +N++L K G IK+ DFG + T+ + + GTP Y++PE++E+ Y
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
D W +G ++YE+ G PFY +L LIL + +++P T+S K+ L GLL KD
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 239 PRQRL-SWPD----LLYHPFIAG 256
P +RL PD ++ H F +G
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSG 407
>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
Length = 465
Score = 167 bits (423), Expect = 6e-41
Identities = 92/263 (34%), Positives = 152/263 (57%), Gaps = 7/263 (2%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M + L+++G+G+FG+V R K S + A+K + K + ++ E+ + E +++ R
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + SF+T + V +Y G ELF L + ED+ + A++VSAL YLHS
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+I++RD+K +N++L K G IK+ DFG + T+ + + GTP Y++PE++E+ Y
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
D W +G ++YE+ G PFY +L LIL + +++P T+S K+ L GLL KD
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 239 PRQRL-SWPD----LLYHPFIAG 256
P +RL PD ++ H F +G
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSG 407
>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
Length = 472
Score = 167 bits (423), Expect = 6e-41
Identities = 104/279 (37%), Positives = 163/279 (58%), Gaps = 16/279 (5%)
Query: 1 MEKYHVLEMIGEGSFGRVYKG-RRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLR 59
++ + + E +G G++ VYK +K + +VVA+K + K ++ + NL EIEI++G+R
Sbjct: 11 LDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIR 70
Query: 60 HPNIVHMLD-SFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP+IV + D +++D +++ A G+L + + LPE + QL SAL +LH
Sbjct: 71 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130
Query: 119 HRILHRDMKPQNILLA--KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERP 176
I H D+KPQNILL+ + +KL DFGFA+ MS ++G+PLYM+PE+V +R
Sbjct: 131 RNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHV-LRGSPLYMAPEMVCQRQ 189
Query: 177 YDHTADLWSVGCILYELAVGTPPFYATSIFQL-----VSLILKDPVRWPSTISPCFKNFL 231
YD DLWS+G ILYE G PPF + S +L + +++ P+R P C ++ L
Sbjct: 190 YDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLR-PLLSRDC-RDLL 247
Query: 232 QGLLTKDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLG 270
Q LL +DP +R+S+ D HP+ V + P+G LG
Sbjct: 248 QRLLERDPSRRISFQDFFAHPW----VDLEHMPSGESLG 282
>gi|217330559 unc-51-like kinase 2 [Homo sapiens]
Length = 1036
Score = 166 bits (420), Expect = 1e-40
Identities = 99/266 (37%), Positives = 150/266 (56%), Gaps = 16/266 (6%)
Query: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQ-VVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61
+Y +++G G+F V++GR + VA+K I K S+ ++ L +EI+I++ L+H
Sbjct: 8 EYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQIL-LGKEIKILKELQHE 66
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
NIV + D E V +V +Y G +L L+ G L ED ++ Q+ +A+ LHS
Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG 126
Query: 121 ILHRDMKPQNILLA---------KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
I+HRD+KPQNILL+ G IK+ DFGFAR + +N M T + G+P+YM+PE+
Sbjct: 127 IIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAAT-LCGSPMYMAPEV 185
Query: 172 VEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPS---TISPCFK 228
+ + YD ADLWS+G ++Y+ VG PPF A S L K+ PS SP
Sbjct: 186 IMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLA 245
Query: 229 NFLQGLLTKDPRQRLSWPDLLYHPFI 254
N L GLL ++ + R+ + HPF+
Sbjct: 246 NLLLGLLQRNQKDRMDFEAFFSHPFL 271
>gi|217330557 unc-51-like kinase 2 [Homo sapiens]
Length = 1036
Score = 166 bits (420), Expect = 1e-40
Identities = 99/266 (37%), Positives = 150/266 (56%), Gaps = 16/266 (6%)
Query: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQ-VVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61
+Y +++G G+F V++GR + VA+K I K S+ ++ L +EI+I++ L+H
Sbjct: 8 EYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQIL-LGKEIKILKELQHE 66
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
NIV + D E V +V +Y G +L L+ G L ED ++ Q+ +A+ LHS
Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG 126
Query: 121 ILHRDMKPQNILLA---------KGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPEL 171
I+HRD+KPQNILL+ G IK+ DFGFAR + +N M T + G+P+YM+PE+
Sbjct: 127 IIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAAT-LCGSPMYMAPEV 185
Query: 172 VEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPS---TISPCFK 228
+ + YD ADLWS+G ++Y+ VG PPF A S L K+ PS SP
Sbjct: 186 IMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLA 245
Query: 229 NFLQGLLTKDPRQRLSWPDLLYHPFI 254
N L GLL ++ + R+ + HPF+
Sbjct: 246 NLLLGLLQRNQKDRMDFEAFFSHPFL 271
>gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [Homo
sapiens]
Length = 431
Score = 165 bits (418), Expect = 2e-40
Identities = 108/324 (33%), Positives = 169/324 (52%), Gaps = 21/324 (6%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLG-RSEKELRNLQREIEIM-RGLRHP 61
+H L++IG+GSFG+V R K A+K + K +KE +++ E ++ + ++HP
Sbjct: 98 FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
+V + SF+T ++ V DY G ELF L+ + E + + AA++ SAL YLHS
Sbjct: 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 217
Query: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
I++RD+KP+NILL G I L DFG + + ++ GTP Y++PE++ ++PYD T
Sbjct: 218 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRT 277
Query: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
D W +G +LYE+ G PPFY+ + ++ IL P++ I+ ++ L+GLL KD
Sbjct: 278 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT 337
Query: 241 QRLSWPDLLYHPFIAGHVTI------------ITEPAGPDLGTPFTSR-LPPELQVLKDE 287
+RL D I HV IT P P++ P R PE +E
Sbjct: 338 KRLGAKDDFME--IKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPE---FTEE 392
Query: 288 QAHRLAPKGNQSRILTQAYKRMAE 311
K S ++T + K AE
Sbjct: 393 PVPNSIGKSPDSVLVTASVKEAAE 416
>gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4
[Homo sapiens]
Length = 445
Score = 165 bits (418), Expect = 2e-40
Identities = 108/324 (33%), Positives = 169/324 (52%), Gaps = 21/324 (6%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLG-RSEKELRNLQREIEIM-RGLRHP 61
+H L++IG+GSFG+V R K A+K + K +KE +++ E ++ + ++HP
Sbjct: 112 FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 171
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
+V + SF+T ++ V DY G ELF L+ + E + + AA++ SAL YLHS
Sbjct: 172 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 231
Query: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
I++RD+KP+NILL G I L DFG + + ++ GTP Y++PE++ ++PYD T
Sbjct: 232 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRT 291
Query: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
D W +G +LYE+ G PPFY+ + ++ IL P++ I+ ++ L+GLL KD
Sbjct: 292 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT 351
Query: 241 QRLSWPDLLYHPFIAGHVTI------------ITEPAGPDLGTPFTSR-LPPELQVLKDE 287
+RL D I HV IT P P++ P R PE +E
Sbjct: 352 KRLGAKDDFME--IKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPE---FTEE 406
Query: 288 QAHRLAPKGNQSRILTQAYKRMAE 311
K S ++T + K AE
Sbjct: 407 PVPNSIGKSPDSVLVTASVKEAAE 430
>gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3
[Homo sapiens]
Length = 459
Score = 165 bits (418), Expect = 2e-40
Identities = 108/324 (33%), Positives = 169/324 (52%), Gaps = 21/324 (6%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLG-RSEKELRNLQREIEIM-RGLRHP 61
+H L++IG+GSFG+V R K A+K + K +KE +++ E ++ + ++HP
Sbjct: 126 FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 185
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
+V + SF+T ++ V DY G ELF L+ + E + + AA++ SAL YLHS
Sbjct: 186 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 245
Query: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
I++RD+KP+NILL G I L DFG + + ++ GTP Y++PE++ ++PYD T
Sbjct: 246 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRT 305
Query: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
D W +G +LYE+ G PPFY+ + ++ IL P++ I+ ++ L+GLL KD
Sbjct: 306 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT 365
Query: 241 QRLSWPDLLYHPFIAGHVTI------------ITEPAGPDLGTPFTSR-LPPELQVLKDE 287
+RL D I HV IT P P++ P R PE +E
Sbjct: 366 KRLGAKDDFME--IKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPE---FTEE 420
Query: 288 QAHRLAPKGNQSRILTQAYKRMAE 311
K S ++T + K AE
Sbjct: 421 PVPNSIGKSPDSVLVTASVKEAAE 444
>gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2
[Homo sapiens]
Length = 526
Score = 165 bits (418), Expect = 2e-40
Identities = 108/324 (33%), Positives = 169/324 (52%), Gaps = 21/324 (6%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLG-RSEKELRNLQREIEIM-RGLRHP 61
+H L++IG+GSFG+V R K A+K + K +KE +++ E ++ + ++HP
Sbjct: 193 FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 252
Query: 62 NIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHR 120
+V + SF+T ++ V DY G ELF L+ + E + + AA++ SAL YLHS
Sbjct: 253 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 312
Query: 121 ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
I++RD+KP+NILL G I L DFG + + ++ GTP Y++PE++ ++PYD T
Sbjct: 313 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRT 372
Query: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
D W +G +LYE+ G PPFY+ + ++ IL P++ I+ ++ L+GLL KD
Sbjct: 373 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT 432
Query: 241 QRLSWPDLLYHPFIAGHVTI------------ITEPAGPDLGTPFTSR-LPPELQVLKDE 287
+RL D I HV IT P P++ P R PE +E
Sbjct: 433 KRLGAKDDFME--IKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPE---FTEE 487
Query: 288 QAHRLAPKGNQSRILTQAYKRMAE 311
K S ++T + K AE
Sbjct: 488 PVPNSIGKSPDSVLVTASVKEAAE 511
>gi|62241015 AKT1 kinase [Homo sapiens]
Length = 480
Score = 164 bits (416), Expect = 4e-40
Identities = 91/266 (34%), Positives = 154/266 (57%), Gaps = 8/266 (3%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M ++ L+++G+G+FG+V + K + + A+K + K + ++ E+ + E +++ R
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + SF+T + V +YA G ELF L + ED+ + A++VSAL YLHS
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 119 HR-ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
+ +++RD+K +N++L K G IK+ DFG + + + + GTP Y++PE++E+ Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTK 237
D W +G ++YE+ G PFY +L LIL + +R+P T+ P K+ L GLL K
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKK 386
Query: 238 DPRQRLSW-----PDLLYHPFIAGHV 258
DP+QRL +++ H F AG V
Sbjct: 387 DPKQRLGGGSEDAKEIMQHRFFAGIV 412
>gi|62241013 AKT1 kinase [Homo sapiens]
Length = 480
Score = 164 bits (416), Expect = 4e-40
Identities = 91/266 (34%), Positives = 154/266 (57%), Gaps = 8/266 (3%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M ++ L+++G+G+FG+V + K + + A+K + K + ++ E+ + E +++ R
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + SF+T + V +YA G ELF L + ED+ + A++VSAL YLHS
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 119 HR-ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
+ +++RD+K +N++L K G IK+ DFG + + + + GTP Y++PE++E+ Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTK 237
D W +G ++YE+ G PFY +L LIL + +R+P T+ P K+ L GLL K
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKK 386
Query: 238 DPRQRLSW-----PDLLYHPFIAGHV 258
DP+QRL +++ H F AG V
Sbjct: 387 DPKQRLGGGSEDAKEIMQHRFFAGIV 412
>gi|62241011 AKT1 kinase [Homo sapiens]
Length = 480
Score = 164 bits (416), Expect = 4e-40
Identities = 91/266 (34%), Positives = 154/266 (57%), Gaps = 8/266 (3%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M ++ L+++G+G+FG+V + K + + A+K + K + ++ E+ + E +++ R
Sbjct: 147 MNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + SF+T + V +YA G ELF L + ED+ + A++VSAL YLHS
Sbjct: 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 119 HR-ILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
+ +++RD+K +N++L K G IK+ DFG + + + + GTP Y++PE++E+ Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTK 237
D W +G ++YE+ G PFY +L LIL + +R+P T+ P K+ L GLL K
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKK 386
Query: 238 DPRQRLSW-----PDLLYHPFIAGHV 258
DP+QRL +++ H F AG V
Sbjct: 387 DPKQRLGGGSEDAKEIMQHRFFAGIV 412
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 164 bits (415), Expect = 5e-40
Identities = 91/258 (35%), Positives = 152/258 (58%), Gaps = 9/258 (3%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK---LGRSEKELRNLQREIEIMRGLRH 60
+ L++IG+GSFG+V +RK + A+K + K L R E++ +R + +++ ++H
Sbjct: 162 FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNV-LLKNVKH 220
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSH 119
P +V + SF+T +++ V D+ G ELF L+ + PE + + AA++ SAL YLHS
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 120 RILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDH 179
+I++RD+KP+NILL G + L DFG + + T+ GTP Y++PE++ ++PYD+
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 180 TADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDP 239
T D W +G +LYE+ G PPFY + ++ IL P+ +S + L+ LL KD
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 240 RQRL----SWPDLLYHPF 253
+ RL + ++ HPF
Sbjct: 401 QNRLGAKEDFLEIQNHPF 418
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 164 bits (415), Expect = 5e-40
Identities = 91/258 (35%), Positives = 152/258 (58%), Gaps = 9/258 (3%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK---LGRSEKELRNLQREIEIMRGLRH 60
+ L++IG+GSFG+V +RK + A+K + K L R E++ +R + +++ ++H
Sbjct: 162 FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNV-LLKNVKH 220
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSH 119
P +V + SF+T +++ V D+ G ELF L+ + PE + + AA++ SAL YLHS
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 120 RILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDH 179
+I++RD+KP+NILL G + L DFG + + T+ GTP Y++PE++ ++PYD+
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 180 TADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDP 239
T D W +G +LYE+ G PPFY + ++ IL P+ +S + L+ LL KD
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 240 RQRL----SWPDLLYHPF 253
+ RL + ++ HPF
Sbjct: 401 QNRLGAKEDFLEIQNHPF 418
>gi|4502023 AKT2 kinase [Homo sapiens]
Length = 481
Score = 164 bits (414), Expect = 7e-40
Identities = 86/245 (35%), Positives = 146/245 (59%), Gaps = 2/245 (0%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-LGRSEKELRNLQREIEIMRGLR 59
M + L+++G+G+FG+V R K + + A+K + K + ++ E+ + E +++ R
Sbjct: 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HP + + +F+T + V +YA G ELF L + E++ + A++VSAL YLHS
Sbjct: 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHS 268
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
+++RD+K +N++L K G IK+ DFG + ++ + + GTP Y++PE++E+ Y
Sbjct: 269 RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYG 328
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
D W +G ++YE+ G PFY +L LIL + +R+P T+SP K+ L GLL KD
Sbjct: 329 RAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKD 388
Query: 239 PRQRL 243
P+QRL
Sbjct: 389 PKQRL 393
>gi|41872673 NIMA-related kinase 1 [Homo sapiens]
Length = 1258
Score = 160 bits (406), Expect = 6e-39
Identities = 98/268 (36%), Positives = 147/268 (54%), Gaps = 4/268 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
MEKY L+ IGEGSFG+ + + +K I S KE +RE+ ++ ++H
Sbjct: 1 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKH 60
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEG-ELFQ-ILEDDGKL-PEDQVQAIAAQLVSALYYLH 117
PNIV +SFE + + +V DY EG +LF+ I G L EDQ+ Q+ AL ++H
Sbjct: 61 PNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH 120
Query: 118 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
+ILHRD+K QNI L K G ++L DFG AR +++ + + GTP Y+SPE+ E +PY
Sbjct: 121 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPY 180
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPST-ISPCFKNFLQGLLT 236
++ +D+W++GC+LYEL F A S+ LV I+ S S ++ + L
Sbjct: 181 NNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFK 240
Query: 237 KDPRQRLSWPDLLYHPFIAGHVTIITEP 264
++PR R S +L FIA + P
Sbjct: 241 RNPRDRPSVNSILEKGFIAKRIEKFLSP 268
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 160 bits (406), Expect = 6e-39
Identities = 94/265 (35%), Positives = 148/265 (55%), Gaps = 20/265 (7%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63
+ ++ +G+G+FG+VYK + K ++ + A K I +SE+EL + EI+I+ HPNI
Sbjct: 34 WEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDT--KSEEELEDYMVEIDILASCDHPNI 91
Query: 64 VHMLDSFETDKEVVVVTDYAEGELFQ--ILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 121
V +LD+F + + ++ ++ G +LE + L E Q+Q + Q + AL YLH ++I
Sbjct: 92 VKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKI 151
Query: 122 LHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELV-----EERP 176
+HRD+K NIL G IKL DFG + + S GTP +M+PE+V ++RP
Sbjct: 152 IHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRP 211
Query: 177 YDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILK-------DPVRWPSTISPCFKN 229
YD+ AD+WS+G L E+A PP + + +++ I K P RW S FK+
Sbjct: 212 YDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSN----FKD 267
Query: 230 FLQGLLTKDPRQRLSWPDLLYHPFI 254
FL+ L K+ R + LL HPF+
Sbjct: 268 FLKKCLEKNVDARWTTSQLLQHPFV 292
>gi|23510391 NIMA-related kinase 3 isoform a [Homo sapiens]
Length = 506
Score = 160 bits (405), Expect = 7e-39
Identities = 108/328 (32%), Positives = 175/328 (53%), Gaps = 14/328 (4%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
M+ Y VL MIGEGSFGR + + S Q+ A+K I +L +S +N ++E ++ ++H
Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEI-RLPKSFSNTQNSRKEAVLLAKMKH 59
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEG-ELFQ-ILEDDGKL-PEDQVQAIAAQLVSALYYLH 117
PNIV +SFE + + +V +Y +G +L Q I + GKL PED + Q+ + ++H
Sbjct: 60 PNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIH 119
Query: 118 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
R+LHRD+K +NI L + G +KL DFG AR +S + GTP Y+ PE+ E PY
Sbjct: 120 KKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPY 179
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVR-WPSTISPCFKNFLQGLLT 236
++ +D+WS+GCILYEL PF A S L+ + + + PS S + ++ +
Sbjct: 180 NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLVKQMFK 239
Query: 237 KDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKG 296
++P R S LL +A ++ + P++ + + L+ +K+ + + K
Sbjct: 240 RNPSHRPSATTLLSRGIVA---RLVQKCLPPEIIMEYGEEV---LEEIKNSKHNTPRKKT 293
Query: 297 NQSRI---LTQAYKRMAEEAMQKKHQNT 321
N SRI L + EE +K +T
Sbjct: 294 NPSRIRIALGNEASTVQEEEQDRKGSHT 321
>gi|23510393 NIMA-related kinase 3 isoform a [Homo sapiens]
Length = 506
Score = 160 bits (405), Expect = 7e-39
Identities = 108/328 (32%), Positives = 175/328 (53%), Gaps = 14/328 (4%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60
M+ Y VL MIGEGSFGR + + S Q+ A+K I +L +S +N ++E ++ ++H
Sbjct: 1 MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEI-RLPKSFSNTQNSRKEAVLLAKMKH 59
Query: 61 PNIVHMLDSFETDKEVVVVTDYAEG-ELFQ-ILEDDGKL-PEDQVQAIAAQLVSALYYLH 117
PNIV +SFE + + +V +Y +G +L Q I + GKL PED + Q+ + ++H
Sbjct: 60 PNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIH 119
Query: 118 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
R+LHRD+K +NI L + G +KL DFG AR +S + GTP Y+ PE+ E PY
Sbjct: 120 KKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPY 179
Query: 178 DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVR-WPSTISPCFKNFLQGLLT 236
++ +D+WS+GCILYEL PF A S L+ + + + PS S + ++ +
Sbjct: 180 NNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLVKQMFK 239
Query: 237 KDPRQRLSWPDLLYHPFIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKG 296
++P R S LL +A ++ + P++ + + L+ +K+ + + K
Sbjct: 240 RNPSHRPSATTLLSRGIVA---RLVQKCLPPEIIMEYGEEV---LEEIKNSKHNTPRKKT 293
Query: 297 NQSRI---LTQAYKRMAEEAMQKKHQNT 321
N SRI L + EE +K +T
Sbjct: 294 NPSRIRIALGNEASTVQEEEQDRKGSHT 321
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 159 bits (403), Expect = 1e-38
Identities = 89/253 (35%), Positives = 145/253 (57%), Gaps = 3/253 (1%)
Query: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNI 63
Y +L IG+G+F +V R + + VA+K I K + L+ L RE+ IM+GL HPNI
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNI 118
Query: 64 VHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRIL 122
V + + ET+K + +V +YA GE+F L G++ E + +A Q+VSA++Y H I+
Sbjct: 119 VKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIV 178
Query: 123 HRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD-HTA 181
HRD+K +N+LL IK+ DFGF+ + + L + G+P Y +PEL + + YD
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFTLGSK-LDTFCGSPPYAAPELFQGKKYDGPEV 237
Query: 182 DLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQ 241
D+WS+G ILY L G+ PF ++ +L +L+ R P +S ++ L+ L +P +
Sbjct: 238 DIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAK 297
Query: 242 RLSWPDLLYHPFI 254
R + ++ +I
Sbjct: 298 RCTLEQIMKDKWI 310
>gi|21361358 serine/threonine kinase 25 [Homo sapiens]
Length = 426
Score = 158 bits (399), Expect = 4e-38
Identities = 91/254 (35%), Positives = 141/254 (55%), Gaps = 2/254 (0%)
Query: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHP 61
E + L+ IG+GSFG VYKG ++ +VVA+K I L +E E+ ++Q+EI ++ P
Sbjct: 18 ELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIID-LEEAEDEIEDIQQEITVLSQCDSP 76
Query: 62 NIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI 121
I S+ ++ ++ +Y G L G L E + I +++ L YLHS R
Sbjct: 77 YITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK 136
Query: 122 LHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTA 181
+HRD+K N+LL++ G +KL DFG A ++ + + GTP +M+PE++++ YD A
Sbjct: 137 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA 196
Query: 182 DLWSVGCILYELAVGTPPFYATSIFQLVSLILKD-PVRWPSTISPCFKNFLQGLLTKDPR 240
D+WS+G ELA G PP +++ LI K+ P S FK F++ L KDPR
Sbjct: 197 DIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPR 256
Query: 241 QRLSWPDLLYHPFI 254
R + +LL H FI
Sbjct: 257 FRPTAKELLKHKFI 270
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 157 bits (398), Expect = 5e-38
Identities = 86/259 (33%), Positives = 144/259 (55%), Gaps = 4/259 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
+E + + +G+G FG VY R K S ++ALK + K + + + L+RE+EI LR
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + F V ++ +YA G +++ L+ K E + +L +AL Y HS
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
R++HRD+KP+N+LL G +K+ DFG++ ++ T++ GT Y+ PE++E R +D
Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR--TTLCGTLDYLPPEMIEGRMHD 307
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLWS+G + YE VG PPF A + + I + +P ++ ++ + LL +
Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
Query: 239 PRQRLSWPDLLYHPFIAGH 257
P QR ++L HP+I +
Sbjct: 368 PSQRPMLREVLEHPWITAN 386
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 157 bits (398), Expect = 5e-38
Identities = 86/259 (33%), Positives = 144/259 (55%), Gaps = 4/259 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
+E + + +G+G FG VY R K S ++ALK + K + + + L+RE+EI LR
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + F V ++ +YA G +++ L+ K E + +L +AL Y HS
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
R++HRD+KP+N+LL G +K+ DFG++ ++ T++ GT Y+ PE++E R +D
Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR--TTLCGTLDYLPPEMIEGRMHD 307
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLWS+G + YE VG PPF A + + I + +P ++ ++ + LL +
Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
Query: 239 PRQRLSWPDLLYHPFIAGH 257
P QR ++L HP+I +
Sbjct: 368 PSQRPMLREVLEHPWITAN 386
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 157 bits (398), Expect = 5e-38
Identities = 86/259 (33%), Positives = 144/259 (55%), Gaps = 4/259 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
+E + + +G+G FG VY R K S ++ALK + K + + + L+RE+EI LR
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + F V ++ +YA G +++ L+ K E + +L +AL Y HS
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
R++HRD+KP+N+LL G +K+ DFG++ ++ T++ GT Y+ PE++E R +D
Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR--TTLCGTLDYLPPEMIEGRMHD 307
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLWS+G + YE VG PPF A + + I + +P ++ ++ + LL +
Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
Query: 239 PRQRLSWPDLLYHPFIAGH 257
P QR ++L HP+I +
Sbjct: 368 PSQRPMLREVLEHPWITAN 386
>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 157 bits (398), Expect = 5e-38
Identities = 86/259 (33%), Positives = 144/259 (55%), Gaps = 4/259 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
+E + + +G+G FG VY R K S ++ALK + K + + + L+RE+EI LR
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + F V ++ +YA G +++ L+ K E + +L +AL Y HS
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
R++HRD+KP+N+LL G +K+ DFG++ ++ T++ GT Y+ PE++E R +D
Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR--TTLCGTLDYLPPEMIEGRMHD 307
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLWS+G + YE VG PPF A + + I + +P ++ ++ + LL +
Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
Query: 239 PRQRLSWPDLLYHPFIAGH 257
P QR ++L HP+I +
Sbjct: 368 PSQRPMLREVLEHPWITAN 386
>gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 157 bits (398), Expect = 5e-38
Identities = 86/259 (33%), Positives = 144/259 (55%), Gaps = 4/259 (1%)
Query: 1 MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLR 59
+E + + +G+G FG VY R K S ++ALK + K + + + L+RE+EI LR
Sbjct: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
Query: 60 HPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHS 118
HPNI+ + F V ++ +YA G +++ L+ K E + +L +AL Y HS
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 249
Query: 119 HRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYD 178
R++HRD+KP+N+LL G +K+ DFG++ ++ T++ GT Y+ PE++E R +D
Sbjct: 250 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRR--TTLCGTLDYLPPEMIEGRMHD 307
Query: 179 HTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKD 238
DLWS+G + YE VG PPF A + + I + +P ++ ++ + LL +
Sbjct: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
Query: 239 PRQRLSWPDLLYHPFIAGH 257
P QR ++L HP+I +
Sbjct: 368 PSQRPMLREVLEHPWITAN 386
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,505,473
Number of Sequences: 37866
Number of extensions: 2520063
Number of successful extensions: 10863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 721
Number of HSP's successfully gapped in prelim test: 133
Number of HSP's that attempted gapping in prelim test: 7840
Number of HSP's gapped (non-prelim): 1290
length of query: 1315
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1201
effective length of database: 13,930,794
effective search space: 16730883594
effective search space used: 16730883594
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.