Guide to the Human Genome
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Search of human proteins with 21553315

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21553315 phosphatidylinositol glycan anchor biosynthesis,
class M [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21553315 phosphatidylinositol glycan anchor biosynthesis, cla...   870   0.0  
gi|17998700 phosphatidylinositol glycan anchor biosynthesis, cla...    49   7e-06
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]          35   0.17 
gi|5730031 secretory carrier membrane protein 2 [Homo sapiens]         32   0.83 
gi|52218844 olfactory receptor, family 10, subfamily H, member 5...    32   1.1  
gi|7706117 solute carrier family 15, member 3 [Homo sapiens]           32   1.4  
gi|7330337 olfactory receptor, family 10, subfamily H, member 2 ...    30   5.4  
gi|4502073 amelogenin, Y-linked precursor [Homo sapiens]               29   9.2  
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]    29   9.2  

>gi|21553315 phosphatidylinositol glycan anchor biosynthesis, class
           M [Homo sapiens]
          Length = 423

 Score =  870 bits (2249), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MGSTKHWGEWLLNLKVAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAAR 60
           MGSTKHWGEWLLNLKVAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAAR
Sbjct: 1   MGSTKHWGEWLLNLKVAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAAR 60

Query: 61  FVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLG 120
           FVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLG
Sbjct: 61  FVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLG 120

Query: 121 RRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMK 180
           RRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMK
Sbjct: 121 RRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMK 180

Query: 181 IYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFA 240
           IYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFA
Sbjct: 181 IYPVTYILPITLHLLPDRDNDKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFA 240

Query: 241 LSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLI 300
           LSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLI
Sbjct: 241 LSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLI 300

Query: 301 LLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL 360
           LLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL
Sbjct: 301 LLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVL 360

Query: 361 LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTERI 420
           LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTERI
Sbjct: 361 LMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQIISHYKEEPLTERI 420

Query: 421 KYD 423
           KYD
Sbjct: 421 KYD 423


>gi|17998700 phosphatidylinositol glycan anchor biosynthesis, class
           U [Homo sapiens]
          Length = 435

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 74/322 (22%), Positives = 118/322 (36%), Gaps = 60/322 (18%)

Query: 65  GRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLL---------- 114
           G SPY  A +  TPL+ +L    I  +EL    +F+  D LTA  LY  +          
Sbjct: 54  GVSPYSGAVFHETPLIIYLFHFLIDYAEL----VFMITDALTAIALYFAIQDFNKVVFKK 109

Query: 115 --LLKGLG----------------RRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLM 156
             LL  L                 R       +F+LLNP  +      +  +I  +L+  
Sbjct: 110 QKLLLELDQYAPDVAELIRTPMEMRYIPLKVALFYLLNPYTILSCVAKSTCAINNTLIAF 169

Query: 157 VLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLL-----PDRDNDKSLRQFRYTF 211
            +    K     +A+F   A +  +YP+T  +P  L+LL     P +   K+   F + +
Sbjct: 170 FILTTIKGSAFLSAIFLALATYQSLYPLTLFVPGLLYLLQRQYIPVKMKSKAFWIFSWEY 229

Query: 212 QACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNF 271
            A +Y          V   V +  L+FF LS        W+F+   Y + L+  D+  N 
Sbjct: 230 -AMMY----------VGSLVVIICLSFFLLS-------SWDFIPAVYGFILSVPDLTPNI 271

Query: 272 SPYFYMLYLTAESKWSFSLGIAAFLPQLILLSAVSFA--YYRDLVFCCFLHTSIFVTFNK 329
             ++Y     AE    FSL         +    +  A       +F  F+  ++   F  
Sbjct: 272 GLFWYFF---AEMFEHFSLFFVCVFQINVFFYTIPLAIKLKEHPIFFMFIQIAVIAIFKS 328

Query: 330 VCTSQYFLWYLCLLPLVMPLVR 351
             T      Y+   P+   L R
Sbjct: 329 YPTVGDVALYMAFFPVWNHLYR 350


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 40  DRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLF 99
           DR L +RY      + T     VT G    L A   Y PL+GW   P    SELF     
Sbjct: 130 DRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPR-PCSELFP---L 185

Query: 100 ISCDLLTAFLLYRLLLLKGL 119
           I  D L ++LL+   L  G+
Sbjct: 186 IPNDYLLSWLLFIAFLFSGI 205


>gi|5730031 secretory carrier membrane protein 2 [Homo sapiens]
          Length = 329

 Score = 32.3 bits (72), Expect = 0.83
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 18/101 (17%)

Query: 321 TSIFVTFNKVCTSQYFLWYLCLLPLVMPLVR-MPWKRA-------VVLLMLWFI-----G 367
           T I   + ++C   Y+LW L  + L + L+  + W            L +LWF+      
Sbjct: 139 TEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSKGVDFGLSILWFLIFTPCA 198

Query: 368 QAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLINCSILIQII 408
              W  P Y   F+  N+F F     +FF +  C I I II
Sbjct: 199 FLCWYRPIY-KAFRSDNSFSFF----VFFFVFFCQIGIYII 234


>gi|52218844 olfactory receptor, family 10, subfamily H, member 5
           [Homo sapiens]
          Length = 315

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 14/96 (14%)

Query: 154 VLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQA 213
           +LM L+ +   L+  A V+   ++HM +Y     L IT              +  YT   
Sbjct: 32  LLMYLFTLLGNLLIMATVWSERSLHMPMYLFLCALSIT--------------EILYTVAI 77

Query: 214 CLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEY 249
               L   L  +  + F+A A   FF+ SFGF + +
Sbjct: 78  IPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSF 113


>gi|7706117 solute carrier family 15, member 3 [Homo sapiens]
          Length = 581

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 18/147 (12%)

Query: 15  KVAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATY 74
           + A A V  V  L R A  F+GV  +  L++  T+ ++          T     +L A+Y
Sbjct: 32  RAAGAAVLLVEMLERAA--FFGVTANLVLYLNSTNFNW-----TGEQATRAALVFLGASY 84

Query: 75  RYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGL--GRRQACGYCVFWL 132
              P+ GWL   ++YL    G++  ++  LL       LL       GR   CG      
Sbjct: 85  LLAPVGGWL--ADVYL----GRYRAVALSLLLYLAASGLLPATAFPDGRSSFCGEMP--- 135

Query: 133 LNPLPMAVSSRGNADSIVASLVLMVLY 159
            +PL  A  S G   S  +     VLY
Sbjct: 136 ASPLGPACPSAGCPRSSPSPYCAPVLY 162


>gi|7330337 olfactory receptor, family 10, subfamily H, member 2
           [Homo sapiens]
          Length = 315

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 14/96 (14%)

Query: 154 VLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQFRYTFQA 213
           +LM L+ +   L+  A V+   ++H  +Y    +L              S+ +  YT   
Sbjct: 32  LLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCVL--------------SVSEILYTVAI 77

Query: 214 CLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEY 249
               L   L  +  + F+A A   FF+ SFGF + +
Sbjct: 78  IPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSF 113


>gi|4502073 amelogenin, Y-linked precursor [Homo sapiens]
          Length = 192

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 44 HVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWL 83
          H  Y +  Y+V T    + +  R PY  ++Y Y P+ GWL
Sbjct: 25 HPGYINFSYEVLTPLKWYQSMIRPPY--SSYGYEPMGGWL 62


>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
          Length = 529

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 15/109 (13%)

Query: 280 LTAESKWSFSLGIAAFLPQLILL-----SAVSFAYYRDLVFCCF-------LHTSIFVTF 327
           LT  +K+ FSL ++ FL  +++L     S++   +   +V+C F       + ++  +T 
Sbjct: 59  LTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTL 118

Query: 328 NKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQAMWLAPAY 376
             +   +Y   Y  L P+V P+     +  + L+ +W       L P +
Sbjct: 119 GVIAIDRY---YAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLF 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.334    0.146    0.482 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,985,092
Number of Sequences: 37866
Number of extensions: 619657
Number of successful extensions: 1968
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1964
Number of HSP's gapped (non-prelim): 11
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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