Search of human proteins with 215422355

Search of human proteins with 215422355

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215422355 patatin-like phospholipase domain containing 4
[Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215422355 patatin-like phospholipase domain containing 4 [Hom...   502   e-142
gi|42415471 patatin-like phospholipase domain containing 4 [Homo...   502   e-142
gi|32698724 patatin-like phospholipase domain containing 2 [Homo...   172   2e-43
gi|17196626 patatin-like phospholipase domain containing 3 [Homo...   160   1e-39
gi|238776840 patatin-like phospholipase domain containing 1 isof...   143   1e-34
gi|20304127 patatin-like phospholipase domain containing 5 [Homo...   135   3e-32
gi|224593249 patatin-like phospholipase domain containing 1 isof...   107   1e-23
gi|224589138 patatin-like phospholipase domain containing 1 isof...   102   3e-22
gi|239755457 PREDICTED: similar to patatin-like phospholipase do...    55   4e-08
gi|19923477 NEDD8 ultimate buster-1 [Homo sapiens]                     31   1.2  
gi|157388929 epsin 3 [Homo sapiens]                                    29   3.4  

>gi|215422355 patatin-like phospholipase domain containing 4 [Homo
           sapiens]
          Length = 253

 Score =  502 bits (1293), Expect = e-142
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE 60
           MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE
Sbjct: 1   MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE 60

Query: 61  ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT 120
           ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT
Sbjct: 61  ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT 120

Query: 121 RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT 180
           RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT
Sbjct: 121 RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT 180

Query: 181 ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD 240
           ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD
Sbjct: 181 ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD 240

Query: 241 DTVKFLLKENWFE 253
           DTVKFLLKENWFE
Sbjct: 241 DTVKFLLKENWFE 253


>gi|42415471 patatin-like phospholipase domain containing 4 [Homo
           sapiens]
          Length = 253

 Score =  502 bits (1293), Expect = e-142
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE 60
           MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE
Sbjct: 1   MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIE 60

Query: 61  ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT 120
           ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT
Sbjct: 61  ECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKT 120

Query: 121 RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT 180
           RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT
Sbjct: 121 RENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVT 180

Query: 181 ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD 240
           ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD
Sbjct: 181 ISPFSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFD 240

Query: 241 DTVKFLLKENWFE 253
           DTVKFLLKENWFE
Sbjct: 241 DTVKFLLKENWFE 253


>gi|32698724 patatin-like phospholipase domain containing 2 [Homo
           sapiens]
          Length = 504

 Score =  172 bits (437), Expect = 2e-43
 Identities = 90/242 (37%), Positives = 145/242 (59%), Gaps = 1/242 (0%)

Query: 5   NLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQ 64
           N+SFA CGFLG+Y++G AS L  H   LV +     GASAG+L A+ L+T     E   +
Sbjct: 9   NISFAGCGFLGVYYVGVASCLREHAPFLVANATHIYGASAGALTATALVTGVCLGEAGAK 68

Query: 65  FTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTRENH 124
           F  + ++E R++  G + P ++ +  +RS +  +LP  +HE A  RL +S+T     EN 
Sbjct: 69  FI-EVSKEARKRFLGPLHPSFNLVKIIRSFLLKVLPADSHEHASGRLGISLTRVSDGENV 127

Query: 125 LVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPF 184
           ++S F+S+++LI+  + S F+P+Y GL     +G ++VDGG+++ LP+  +  T+T+SPF
Sbjct: 128 IISHFNSKDELIQANVCSGFIPVYCGLIPPSLQGVRYVDGGISDNLPLYELKNTITVSPF 187

Query: 185 SGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVK 244
           SG  DI PQD       + +    I  +L NL RL++ALFPP    +  + + G+ D ++
Sbjct: 188 SGESDICPQDSSTNIHELRVTNTSIQFNLRNLYRLSKALFPPEPLVLREMCKQGYRDGLR 247

Query: 245 FL 246
           FL
Sbjct: 248 FL 249


>gi|17196626 patatin-like phospholipase domain containing 3 [Homo
           sapiens]
          Length = 481

 Score =  160 bits (404), Expect = 1e-39
 Identities = 85/243 (34%), Positives = 135/243 (55%), Gaps = 3/243 (1%)

Query: 5   NLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSL-VASVLLTAPEKIEECN 63
           +LSFA CGFLG YH+GA   L  H   L++D +   GASAG+L    VL   P  +E+  
Sbjct: 9   SLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIP--LEQTL 66

Query: 64  QFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTREN 123
           Q       + R ++ G   P ++    LR G+   LP + H+L   ++ +S+T     EN
Sbjct: 67  QVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLCKCLPANVHQLISGKIGISLTRVSDGEN 126

Query: 124 HLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISP 183
            LVS F S+++++  L+ S F+P Y+GL    ++G ++VDGG+++ +P +    T+T+SP
Sbjct: 127 VLVSDFRSKDEVVDALVCSCFIPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSP 186

Query: 184 FSGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTV 243
           F G  DI P+ K    L+V+I K  + L   NL  L++A  PP  + +  +   G+ D  
Sbjct: 187 FYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAF 246

Query: 244 KFL 246
           +FL
Sbjct: 247 RFL 249


>gi|238776840 patatin-like phospholipase domain containing 1 isoform
           3 [Homo sapiens]
          Length = 532

 Score =  143 bits (361), Expect = 1e-34
 Identities = 80/246 (32%), Positives = 130/246 (52%), Gaps = 1/246 (0%)

Query: 5   NLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQ 64
           ++SF+  GFL  Y  GA  AL     ++++    FAG SAG+++A++ +   E  E    
Sbjct: 15  SISFSGSGFLSFYQAGAVDALRDLAPRMLETAHRFAGTSAGAVIAALAICGIEMDEYLRV 74

Query: 65  FTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTRENH 124
                AE +++   G ++P    +  +R  +  +LP  ++++   +LHVS+T     EN 
Sbjct: 75  LNVGVAE-VKKSFLGPLSPSCKMVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENV 133

Query: 125 LVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPF 184
           +VS F+S+E+LI+ L  S FVP+Y GL    Y+G +++DGG T   P       +TIS F
Sbjct: 134 VVSEFTSKEELIEALYCSCFVPVYCGLIPPTYRGVRYIDGGFTGMQPCAFWTDAITISTF 193

Query: 185 SGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVK 244
           SG+ DI P+D   +     +       SL N+ R+  ALFPP    +   Y  G++D V 
Sbjct: 194 SGQQDICPRDCPAIFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVL 253

Query: 245 FLLKEN 250
           +L + N
Sbjct: 254 YLRRLN 259


>gi|20304127 patatin-like phospholipase domain containing 5 [Homo
           sapiens]
          Length = 429

 Score =  135 bits (340), Expect = 3e-32
 Identities = 74/242 (30%), Positives = 127/242 (52%), Gaps = 1/242 (0%)

Query: 5   NLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQ 64
           NLSF+  G+LG +H+GA   L +   +L++  +   G+S+G+L A V +   + ++ C  
Sbjct: 11  NLSFSGAGYLGAHHVGATECLRQRAPRLLQGARRIYGSSSGALNA-VSIVCGKSVDFCCS 69

Query: 65  FTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPPSAHELAQNRLHVSITNAKTRENH 124
                  ++ R S   + P Y  +  ++  ++  LPP AH LA  RL +S+T      N 
Sbjct: 70  HLLGMVGQLERLSLSILHPAYAPIEHVKQQLQDALPPDAHVLASQRLGISLTRWPDGRNF 129

Query: 125 LVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPF 184
           LV+ F++ ++LI+ L+ + + P Y GL   E++G++++DG L+N LP      T+T+SPF
Sbjct: 130 LVTDFATCDELIQALVCTLYFPFYCGLIPPEFRGERYIDGALSNNLPFADCPSTITVSPF 189

Query: 185 SGRLDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVK 244
            G +DI PQ        +N+      +S  N       L PPS   +    + G+ D ++
Sbjct: 190 HGTVDICPQSTSPNLHELNVFNFSFQISTENFFLGLICLIPPSLEVVADNCRQGYLDALR 249

Query: 245 FL 246
           FL
Sbjct: 250 FL 251


>gi|224593249 patatin-like phospholipase domain containing 1 isoform
           1 [Homo sapiens]
          Length = 437

 Score =  107 bits (267), Expect = 1e-23
 Identities = 57/160 (35%), Positives = 88/160 (55%)

Query: 91  LRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAG 150
           +R  +  +LP  ++++   +LHVS+T     EN +VS F+S+E+LI+ L  S FVP+Y G
Sbjct: 5   MRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVYCG 64

Query: 151 LKLVEYKGQKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDLYVNIAKQDIM 210
           L    Y+G +++DGG T   P       +TIS FSG+ DI P+D   +     +      
Sbjct: 65  LIPPTYRGVRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIFHDFRMFNCSFQ 124

Query: 211 LSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKEN 250
            SL N+ R+  ALFPP    +   Y  G++D V +L + N
Sbjct: 125 FSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLN 164


>gi|224589138 patatin-like phospholipase domain containing 1 isoform
           2 [Homo sapiens]
          Length = 446

 Score =  102 bits (254), Expect = 3e-22
 Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 9/169 (5%)

Query: 91  LRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAG 150
           +R  +  +LP  ++++   +LHVS+T     EN +VS F+S+E+LI+ L  S FVP+Y G
Sbjct: 5   MRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVYCG 64

Query: 151 LKLVEYKG---------QKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDLY 201
           L    Y+G         Q+++DGG T   P       +TIS FSG+ DI P+D   +   
Sbjct: 65  LIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIFHD 124

Query: 202 VNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKEN 250
             +       SL N+ R+  ALFPP    +   Y  G++D V +L + N
Sbjct: 125 FRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLN 173


>gi|239755457 PREDICTED: similar to patatin-like phospholipase
          domain containing 2 [Homo sapiens]
          Length = 226

 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 26/50 (52%), Positives = 34/50 (68%)

Query: 5  NLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLT 54
          N+SFA CGFLG+Y++G AS L  H   LV +     GASAG+L A+ L+T
Sbjct: 9  NISFAGCGFLGVYYVGVASCLREHAPFLVANATHIYGASAGALTATALVT 58


>gi|19923477 NEDD8 ultimate buster-1 [Homo sapiens]
          Length = 601

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 57  EKIEECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILPP----SAHELAQNRLH 112
           +++E C     K  EEIR ++    T   ++     + +E  LPP        L + RLH
Sbjct: 47  DRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLH 106

Query: 113 VSITNAKTRENHLVSTFSSREDLIKVLL 140
           ++    +   + +  TF  +E+ IK+++
Sbjct: 107 IT---GRELRSKIAETFGLQENYIKIVI 131


>gi|157388929 epsin 3 [Homo sapiens]
          Length = 632

 Score = 29.3 bits (64), Expect = 3.4
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 14  LGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLV-ASVLLTAPEKIEECNQFTYKFAEE 72
           LGI  LG A        +  +  ++F G SA SLV    L+ AP+  +  N F    +  
Sbjct: 476 LGI--LGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAP 533

Query: 73  IRRQSFGAVTPGYDFMARLRSGMESI 98
                FGA  PG   + ++R+G  ++
Sbjct: 534 SPTNPFGAGEPGRPTLNQMRTGSPAL 559


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,850,094
Number of Sequences: 37866
Number of extensions: 338666
Number of successful extensions: 744
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 727
Number of HSP's gapped (non-prelim): 11
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.