Guide to the Human Genome
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Search of human proteins with 215276969

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215276969 dolichyl-phosphate beta-glucosyltransferase
isoform 2 [Homo sapiens]
         (294 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform...   589   e-168
gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1...   573   e-164
gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]     45   8e-05
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...    33   0.39 
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...    33   0.39 
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]                        31   1.1  
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]                       31   1.1  
gi|189217895 KH domain-containing, RNA-binding, signal transduct...    30   1.9  
gi|221219020 NYD-SP11 protein [Homo sapiens]                           30   2.5  
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...    30   2.5  
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...    30   2.5  
gi|218749848 family with sequence similarity 38, member A [Homo ...    29   4.3  
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]                    29   5.7  

>gi|215276969 dolichyl-phosphate beta-glucosyltransferase isoform 2
           [Homo sapiens]
          Length = 294

 Score =  589 bits (1518), Expect = e-168
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60
           MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW
Sbjct: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60

Query: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKYGSDKVRVITLVKNRGKGGAIRMG 120
           DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKYGSDKVRVITLVKNRGKGGAIRMG
Sbjct: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKYGSDKVRVITLVKNRGKGGAIRMG 120

Query: 121 IFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSY 180
           IFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSY
Sbjct: 121 IFSSRGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSY 180

Query: 181 FRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQF 240
           FRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQF
Sbjct: 181 FRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFDVELLYIAQF 240

Query: 241 FKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN 294
           FKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN
Sbjct: 241 FKIPIAEIAVNWTEIEGSKLVPFWSWLQMGKDLLFIRLRYLTGAWRLEQTRKMN 294


>gi|7019323 dolichyl-phosphate beta-glucosyltransferase isoform 1
           [Homo sapiens]
          Length = 324

 Score =  573 bits (1477), Expect = e-164
 Identities = 294/324 (90%), Positives = 294/324 (90%), Gaps = 30/324 (9%)

Query: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60
           MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW
Sbjct: 1   MAPLLLQLAVLGAALAAAALVLISIVAFTTATKMPALHRHEEEKFFLNAKGQKETLPSIW 60

Query: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQK------------------------ 96
           DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQK                        
Sbjct: 61  DSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVA 120

Query: 97  ------YGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 150
                 YGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL
Sbjct: 121 FKYCQKYGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGATKFPDVEKLEKGL 180

Query: 151 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 210
           NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL
Sbjct: 181 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKL 240

Query: 211 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 270
           FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG
Sbjct: 241 FTREAASRTFSSLHVERWAFDVELLYIAQFFKIPIAEIAVNWTEIEGSKLVPFWSWLQMG 300

Query: 271 KDLLFIRLRYLTGAWRLEQTRKMN 294
           KDLLFIRLRYLTGAWRLEQTRKMN
Sbjct: 301 KDLLFIRLRYLTGAWRLEQTRKMN 324


>gi|4503363 dolichyl-phosphate mannosyltransferase 1 [Homo sapiens]
          Length = 260

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 51/231 (22%), Positives = 97/231 (41%), Gaps = 44/231 (19%)

Query: 68  SVVVPSYNEEKRLPVMM------------------------DEALSYLEKRQK-YGSDKV 102
           SV++P+YNE + LP+++                        D      E+ +K YGSD++
Sbjct: 28  SVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRI 87

Query: 103 RVITLVKNRGKGGAIRMGIFSSRGEKILMADADGA--TKF-PDVEKLEKGLNDLQPWPNQ 159
            +    K  G G A   G+  + G  I++ DAD +   KF P+  + +K  N        
Sbjct: 88  LLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGN-------- 139

Query: 160 MAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRT 219
             I  G+R +     +      R ++  G +FL   L   G  D    F+L+ +E   + 
Sbjct: 140 FDIVSGTR-YKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKL 198

Query: 220 FSSLHVERWAFDVELLYIAQFFKIPIAEIAVNW-------TEIEGSKLVPF 263
                 + + F +E++  A+     I E+ +++       +++ G+++V F
Sbjct: 199 IEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSF 249


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score = 32.7 bits (73), Expect = 0.39
 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 13/116 (11%)

Query: 118 RMGIFSS--RGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESI 175
           RMGI     + E +L    D  +K   +   + GL+ ++   + M+ ACG+  ++  E +
Sbjct: 137 RMGIVHRDLKPENLLYYSQDEESK---IMISDFGLSKMEGKGDVMSTACGTPGYVAPEVL 193

Query: 176 AQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFD 231
           AQ+ Y + +  +    + + L         CG+  F  E  S+ F  +    + FD
Sbjct: 194 AQKPYSKAVDCWSIGVIAYILL--------CGYPPFYDENDSKLFEQILKAEYEFD 241


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score = 32.7 bits (73), Expect = 0.39
 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 13/116 (11%)

Query: 118 RMGIFSS--RGEKILMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESI 175
           RMGI     + E +L    D  +K   +   + GL+ ++   + M+ ACG+  ++  E +
Sbjct: 137 RMGIVHRDLKPENLLYYSQDEESK---IMISDFGLSKMEGKGDVMSTACGTPGYVAPEVL 193

Query: 176 AQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAFD 231
           AQ+ Y + +  +    + + L         CG+  F  E  S+ F  +    + FD
Sbjct: 194 AQKPYSKAVDCWSIGVIAYILL--------CGYPPFYDENDSKLFEQILKAEYEFD 241


>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
          Length = 479

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 34/156 (21%), Positives = 54/156 (34%), Gaps = 35/156 (22%)

Query: 130 LMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGF 189
           LM D DG  K  D    ++G+ D       M   CG+  +L  E +    Y R +  +G 
Sbjct: 277 LMLDKDGHIKITDFGLCKEGITDAAT----MKTFCGTPEYLAPEVLEDNDYGRAVDWWGL 332

Query: 190 HFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAF------DVELLYIAQFFKI 243
             +++        +  CG   F  +   + F  + +E   F      D + L      K 
Sbjct: 333 GVVMY--------EMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384

Query: 244 PIAEIA-----------------VNWTEIEGSKLVP 262
           P   +                  VNW ++   KLVP
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP 420


>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
          Length = 465

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 34/156 (21%), Positives = 54/156 (34%), Gaps = 35/156 (22%)

Query: 130 LMADADGATKFPDVEKLEKGLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGF 189
           LM D DG  K  D    ++G+ D       M   CG+  +L  E +    Y R +  +G 
Sbjct: 277 LMLDKDGHIKITDFGLCKEGITDAAT----MKTFCGTPEYLAPEVLEDNDYGRAVDWWGL 332

Query: 190 HFLVWFLCVKGIRDTQCGFKLFTREAASRTFSSLHVERWAF------DVELLYIAQFFKI 243
             +++        +  CG   F  +   + F  + +E   F      D + L      K 
Sbjct: 333 GVVMY--------EMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384

Query: 244 PIAEIA-----------------VNWTEIEGSKLVP 262
           P   +                  VNW ++   KLVP
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP 420


>gi|189217895 KH domain-containing, RNA-binding, signal
           transduction-associated protein 2 [Homo sapiens]
          Length = 349

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 18/88 (20%)

Query: 70  VVPSYNEEKRLPVMMDEALSYLEKRQKYGSDK------VRVITLVKNRGKGGAI------ 117
           +VP YN+E R   + +  LSYL   +  G  +      +R+     +RG+GGAI      
Sbjct: 159 LVPDYNDEIRQEQLRE--LSYLNGSEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPP 216

Query: 118 RMGIFSSRGEKILMADADGATKFPDVEK 145
             G+ + RG  +      GA   P V +
Sbjct: 217 GRGVLTPRGSTV----TRGALPVPPVAR 240


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 20/91 (21%), Positives = 45/91 (49%), Gaps = 2/91 (2%)

Query: 53   KETLPSIWDSPTKQLSVVVPSYNEEKRLPVMMDEALSYLEKRQKYGSDKVRVITLVKN-- 110
            +E   S+ D   ++ S  +    + ++  +  ++     E+R+K    + RV+++++   
Sbjct: 2315 EEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVP 2374

Query: 111  RGKGGAIRMGIFSSRGEKILMADADGATKFP 141
             GKG AIR+G+  S  +K++    +   K P
Sbjct: 2375 HGKGRAIRLGVLKSPLKKLMSTALEMKEKTP 2405


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 149 GLNDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGF 208
           GL+ ++   + ++ ACG+  ++  E +AQ+ Y + +  +    + + L         CG+
Sbjct: 164 GLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILL--------CGY 215

Query: 209 KLFTREAASRTFSSLHVERWAFD 231
             F  E  ++ F  +    + FD
Sbjct: 216 PPFYDENDAKLFEQILKAEYEFD 238


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
           sapiens]
          Length = 476

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 8/72 (11%)

Query: 160 MAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRT 219
           M+ ACG+  ++  E +AQ+ Y + +  +    + + L         CG+  F  E  S+ 
Sbjct: 176 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILL--------CGYPPFYEETESKL 227

Query: 220 FSSLHVERWAFD 231
           F  +    + F+
Sbjct: 228 FEKIKEGYYEFE 239


>gi|218749848 family with sequence similarity 38, member A [Homo
           sapiens]
          Length = 2090

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 15/58 (25%), Positives = 24/58 (41%)

Query: 151 NDLQPWPNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGF 208
           + L P P Q   A G+R  L+++ +    YF     Y F   + FL    +   +  F
Sbjct: 525 HQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNF 582


>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
          Length = 862

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 15/94 (15%)

Query: 128 KILMADADGATK-FPDVEKLEKGLNDLQPWPNQMAIACGSRA--------HLEKESIAQR 178
           K+L+A   G++   P V+    G   L P P     +C  +         H EK    + 
Sbjct: 671 KVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQLHSEKTMYLKS 730

Query: 179 SYFRTLLMYGFHFLVWFLCV------KGIRDTQC 206
           S  R L+     F V FLC+      KG    QC
Sbjct: 731 SDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQC 764


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,305,392
Number of Sequences: 37866
Number of extensions: 429413
Number of successful extensions: 1233
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1226
Number of HSP's gapped (non-prelim): 14
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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