Guide to the Human Genome
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Search of human proteins with 11345492

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11345492 serine racemase [Homo sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11345492 serine racemase [Homo sapiens]                            672   0.0  
gi|33469958 serine dehydratase [Homo sapiens]                          97   3e-20
gi|19923959 serine dehydratase-like [Homo sapiens]                     94   2e-19
gi|4557415 cystathionine-beta-synthase [Homo sapiens]                  68   1e-11
gi|50897292 olfactory receptor, family 8, subfamily D, member 2 ...    31   1.4  
gi|168229161 coronin 7 [Homo sapiens]                                  29   5.3  
gi|110349719 titin isoform N2-A [Homo sapiens]                         28   9.0  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      28   9.0  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      28   9.0  
gi|110349715 titin isoform N2-B [Homo sapiens]                         28   9.0  

>gi|11345492 serine racemase [Homo sapiens]
          Length = 340

 Score =  672 bits (1735), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA 60
           MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA
Sbjct: 1   MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA 60

Query: 61  LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA 120
           LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA
Sbjct: 61  LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA 120

Query: 121 YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180
           YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL
Sbjct: 121 YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180

Query: 181 VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV 240
           VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV
Sbjct: 181 VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV 240

Query: 241 KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT 300
           KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT
Sbjct: 241 KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT 300

Query: 301 VSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV 340
           VSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV
Sbjct: 301 VSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV 340


>gi|33469958 serine dehydratase [Homo sapiens]
          Length = 328

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 87/307 (28%), Positives = 146/307 (47%), Gaps = 20/307 (6%)

Query: 26  TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSG 85
           TP+  S  L+++ G +++ K +  Q +GSFKIRG  +  +              V  S+G
Sbjct: 11  TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAH----FVCSSAG 66

Query: 86  NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-VYCEPSDESRENVAKRVTE 144
           N G A  YAA+  G+PA IVVP T P      ++  GA++ V  E  DE+ E +AK + +
Sbjct: 67  NAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFE-LAKALAK 125

Query: 145 ETEG-IMVHPNQEPAVIAGQGTIALEVLNQV-PLVDALVVPVGGGGMLAGIAITVKALK- 201
              G + + P  +P +  G  +I  E+   +     A+ + VGGGG+L G+   ++ +  
Sbjct: 126 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGW 185

Query: 202 PSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIAD--GVKSSIGLNTWPIIRDLVDDI 259
             V V A E   A   + +   GKL+ +L    ++A   GVK ++G     + ++     
Sbjct: 186 GDVPVIAMETFGAHSFHAATTAGKLV-SLPKITSVAKALGVK-TVGAQALKLFQEHPIFS 243

Query: 260 FTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTV-------SPEVKNICIVL 312
             +++ E   A +   +  K+L+EP  G  +AAV S   Q +       +P    + IV 
Sbjct: 244 EVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVC 303

Query: 313 SGGNVDL 319
            G N+ L
Sbjct: 304 GGSNISL 310


>gi|19923959 serine dehydratase-like [Homo sapiens]
          Length = 329

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 88/308 (28%), Positives = 146/308 (47%), Gaps = 28/308 (9%)

Query: 25  LTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSS 84
           +TP+L S  L+Q+ G  +F KCE  Q +GSFKIRG    +     +  ++  + +V  S 
Sbjct: 17  VTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRG----IGHFCQEMAKKGCRHLVCSSG 72

Query: 85  GNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-----VYCEPSDESRENVA 139
           GN G A  YAA+  GIPA IV+P++        +Q  GA +     V+ E +  ++E +A
Sbjct: 73  GNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQE-LA 131

Query: 140 KRVTEETEGIMVHPNQEPAVIAGQGTIALE---VLNQVPLVDALVVPVGGGGMLAG-IAI 195
           KR   E     V P   P +  G  ++  E   VL   P   ALV+ VGGGG+LAG +A 
Sbjct: 132 KRDGWEN----VPPFDHPLIWKGHASLVQELKAVLRTPP--GALVLAVGGGGLLAGVVAG 185

Query: 196 TVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV-KSSIGLNTWPIIRD 254
            ++     V + A E   A  C+ + +    +  L    ++A  +   ++       ++ 
Sbjct: 186 LLEVGWQHVPIIAMETHGA-HCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQV 244

Query: 255 LVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLS------QHFQTVSPEVKNI 308
                  V + E   A Q + +  ++L+EP  G  +AA+ S      Q    + P + ++
Sbjct: 245 CKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSV 304

Query: 309 CIVLSGGN 316
            +++ GGN
Sbjct: 305 VVIVCGGN 312


>gi|4557415 cystathionine-beta-synthase [Homo sapiens]
          Length = 551

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 75/270 (27%), Positives = 110/270 (40%), Gaps = 21/270 (7%)

Query: 42  LFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIP 101
           L  KCE F   GS K R +L  +     D   +    ++  +SGN G  L  AA + G  
Sbjct: 105 LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYR 164

Query: 102 AYIVVPQTAPDCKKLAIQAYGASIVYCE-----PSDESRENVAKRVTEE--TEGIMVHPN 154
             IV+P+     K   ++A GA IV         S ES   VA R+  E     I+    
Sbjct: 165 CIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYR 224

Query: 155 QEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSN 213
                +A   T A E+L Q    +D LV  VG GG + GIA  +K   P  ++   +P  
Sbjct: 225 NASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEG 284

Query: 214 ADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPII--RDLVDDIFTVTEDEIKCAT 271
           +      +L  +     Y  E         IG +  P +  R +VD  F   ++E     
Sbjct: 285 SILAEPEEL-NQTEQTTYEVE--------GIGYDFIPTVLDRTVVDKWFKSNDEEAFTFA 335

Query: 272 QLVWERMKLLIEPTAG--VGVAAVLSQHFQ 299
           +++  +  LL   +AG  V VA   +Q  Q
Sbjct: 336 RMLIAQEGLLCGGSAGSTVAVAVKAAQELQ 365


>gi|50897292 olfactory receptor, family 8, subfamily D, member 2
           [Homo sapiens]
          Length = 311

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 180 LVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETI 236
           +V  VG  GM+  IA++ + L P V  + +  S  D CY S +  K++ N  P E I
Sbjct: 36  VVTVVGNLGMIFLIALSSQ-LYPPVYYFLSHLSFIDLCYSSVITPKMLVNFVPEENI 91


>gi|168229161 coronin 7 [Homo sapiens]
          Length = 925

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 10/85 (11%)

Query: 105 VVPQTAPDCKKLAIQAYGASIVYCE---PSDESRENVAKRVTEET-EGIMVHPNQEPAVI 160
           +VP   PD   L +   G   +YC    P   +   V + V E    G  + P Q  AV+
Sbjct: 264 LVPLLDPDSGLLVLAGKGERQLYCYEVVPQQPALSPVTQCVLESVLRGAALVPRQALAVM 323

Query: 161 AGQGTIALEVLNQVPLVDALVVPVG 185
           +       EVL  + L D  +VP+G
Sbjct: 324 S------CEVLRVLQLSDTAIVPIG 342


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 61/274 (22%), Positives = 110/274 (40%), Gaps = 47/274 (17%)

Query: 39    GRNLFFKCEL-------FQKTGSFKIR-------GALNAVRSL-VPDALERKPKA-VVTH 82
             G+ L+  CEL       ++K G   +        G +  +R+L + DA +       VT 
Sbjct: 11227 GQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTV 11286

Query: 83    SSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRV 142
              + N+ +  +    +E I  ++V P      +   ++  G +I  C   D +++    + 
Sbjct: 11287 ENANNLECSSCVKVVEVIRDWLVKP-----IRDQHVKPKGTAIFAC---DIAKDTPNIKW 11338

Query: 143   TEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMLAGIAI---TVK 198
              +  + I   PN +  ++     + L++ N +P  +    V + G    A + +    V+
Sbjct: 11339 FKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVE 11398

Query: 199   ALKP--SVKVYA-------AEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLN-- 247
              LKP   V +Y        AE S AD   Q KLKG+L+      E  A+G K  + L+  
Sbjct: 11399 LLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKV 11458

Query: 248   --------TWPIIRDLVDDIFTVTEDEIKCATQL 273
                      +  +  +   I TV E E+  A  L
Sbjct: 11459 KLDQAGEVLYQALNAITTAILTVKEIELDFAVPL 11492


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 61/274 (22%), Positives = 110/274 (40%), Gaps = 47/274 (17%)

Query: 39   GRNLFFKCEL-------FQKTGSFKIR-------GALNAVRSL-VPDALERKPKA-VVTH 82
            G+ L+  CEL       ++K G   +        G +  +R+L + DA +       VT 
Sbjct: 4922 GQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTV 4981

Query: 83   SSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRV 142
             + N+ +  +    +E I  ++V P      +   ++  G +I  C   D +++    + 
Sbjct: 4982 ENANNLECSSCVKVVEVIRDWLVKP-----IRDQHVKPKGTAIFAC---DIAKDTPNIKW 5033

Query: 143  TEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMLAGIAI---TVK 198
             +  + I   PN +  ++     + L++ N +P  +    V + G    A + +    V+
Sbjct: 5034 FKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVE 5093

Query: 199  ALKP--SVKVYA-------AEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLN-- 247
             LKP   V +Y        AE S AD   Q KLKG+L+      E  A+G K  + L+  
Sbjct: 5094 LLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKV 5153

Query: 248  --------TWPIIRDLVDDIFTVTEDEIKCATQL 273
                     +  +  +   I TV E E+  A  L
Sbjct: 5154 KLDQAGEVLYQALNAITTAILTVKEIELDFAVPL 5187


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 61/274 (22%), Positives = 110/274 (40%), Gaps = 47/274 (17%)

Query: 39   GRNLFFKCEL-------FQKTGSFKIR-------GALNAVRSL-VPDALERKPKA-VVTH 82
            G+ L+  CEL       ++K G   +        G +  +R+L + DA +       VT 
Sbjct: 4855 GQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTV 4914

Query: 83   SSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRV 142
             + N+ +  +    +E I  ++V P      +   ++  G +I  C   D +++    + 
Sbjct: 4915 ENANNLECSSCVKVVEVIRDWLVKP-----IRDQHVKPKGTAIFAC---DIAKDTPNIKW 4966

Query: 143  TEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMLAGIAI---TVK 198
             +  + I   PN +  ++     + L++ N +P  +    V + G    A + +    V+
Sbjct: 4967 FKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVE 5026

Query: 199  ALKP--SVKVYA-------AEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLN-- 247
             LKP   V +Y        AE S AD   Q KLKG+L+      E  A+G K  + L+  
Sbjct: 5027 LLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKV 5086

Query: 248  --------TWPIIRDLVDDIFTVTEDEIKCATQL 273
                     +  +  +   I TV E E+  A  L
Sbjct: 5087 KLDQAGEVLYQALNAITTAILTVKEIELDFAVPL 5120


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 28.5 bits (62), Expect = 9.0
 Identities = 61/274 (22%), Positives = 110/274 (40%), Gaps = 47/274 (17%)

Query: 39   GRNLFFKCEL-------FQKTGSFKIR-------GALNAVRSL-VPDALERKPKA-VVTH 82
            G+ L+  CEL       ++K G   +        G +  +R+L + DA +       VT 
Sbjct: 4730 GQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTV 4789

Query: 83   SSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRV 142
             + N+ +  +    +E I  ++V P      +   ++  G +I  C   D +++    + 
Sbjct: 4790 ENANNLECSSCVKVVEVIRDWLVKP-----IRDQHVKPKGTAIFAC---DIAKDTPNIKW 4841

Query: 143  TEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMLAGIAI---TVK 198
             +  + I   PN +  ++     + L++ N +P  +    V + G    A + +    V+
Sbjct: 4842 FKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVE 4901

Query: 199  ALKP--SVKVYA-------AEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLN-- 247
             LKP   V +Y        AE S AD   Q KLKG+L+      E  A+G K  + L+  
Sbjct: 4902 LLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKV 4961

Query: 248  --------TWPIIRDLVDDIFTVTEDEIKCATQL 273
                     +  +  +   I TV E E+  A  L
Sbjct: 4962 KLDQAGEVLYQALNAITTAILTVKEIELDFAVPL 4995


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,403,516
Number of Sequences: 37866
Number of extensions: 514162
Number of successful extensions: 1193
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1175
Number of HSP's gapped (non-prelim): 16
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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