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Search of human proteins with 21314764
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
(734 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 1491 0.0
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 457 e-128
gi|157694526 Fc receptor-like 5 [Homo sapiens] 452 e-127
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 344 1e-94
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 344 1e-94
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens] 340 3e-93
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 318 1e-86
gi|50878302 Fc receptor-like B [Homo sapiens] 172 1e-42
gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64... 144 3e-34
gi|157057547 Fc receptor-like 6 [Homo sapiens] 133 7e-31
gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens] 124 2e-28
gi|110347451 platelet/endothelial cell adhesion molecule [Homo s... 111 3e-24
gi|4503675 Fc fragment of IgE, high affinity I, receptor for; al... 102 1e-21
gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isofo... 96 1e-19
gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isofo... 96 1e-19
gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Hom... 95 2e-19
gi|210031822 Fc fragment of IgG, low affinity IIa, receptor isof... 93 8e-19
gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isofo... 92 2e-18
gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isofo... 92 2e-18
gi|50511936 Fc fragment of IgG, low affinity IIa, receptor isofo... 91 4e-18
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 88 3e-17
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 88 3e-17
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 88 3e-17
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 85 3e-16
gi|132814489 low affinity immunoglobulin gamma Fc region recepto... 84 4e-16
gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor (CD... 82 2e-15
gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor (CD... 82 2e-15
gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD1... 82 2e-15
gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor (CD... 80 7e-15
gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor (CD... 80 7e-15
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 1491 bits (3860), Expect = 0.0
Identities = 734/734 (100%), Positives = 734/734 (100%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH
Sbjct: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
Query: 61 DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRC 120
DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRC
Sbjct: 61 DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRC 120
Query: 121 QGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKP 180
QGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKP
Sbjct: 121 QGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKP 180
Query: 181 LNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWS 240
LNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWS
Sbjct: 181 LNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWS 240
Query: 241 RSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLI 300
RSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLI
Sbjct: 241 RSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLI 300
Query: 301 EGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAA 360
EGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAA
Sbjct: 301 EGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAA 360
Query: 361 DNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE 420
DNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE
Sbjct: 361 DNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE 420
Query: 421 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTL 480
DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTL
Sbjct: 421 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTL 480
Query: 481 RAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSG 540
RAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSG
Sbjct: 481 RAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSG 540
Query: 541 NYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARAR 600
NYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARAR
Sbjct: 541 NYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARAR 600
Query: 601 RKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSNP 660
RKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSNP
Sbjct: 601 RKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSNP 660
Query: 661 IYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSRGRAHEEDDEE 720
IYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSRGRAHEEDDEE
Sbjct: 661 IYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSRGRAHEEDDEE 720
Query: 721 NYENVPRVLLASDH 734
NYENVPRVLLASDH
Sbjct: 721 NYENVPRVLLASDH 734
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 457 bits (1175), Expect = e-128
Identities = 227/374 (60%), Positives = 280/374 (74%), Gaps = 3/374 (0%)
Query: 100 DWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNS-VSRDN 158
D L L A VFEGD+++L+CQG+ N + Y+KD K+L + S V D+
Sbjct: 18 DSLTLVAPSSVFEGDSIVLKCQGEQNWKIQKMAYHKDNKELSVFKKFSDFLIQSAVLSDS 77
Query: 159 SKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQ 218
Y C+ + ++ D TS + I+VQELF PVL ASS PIEG P++L CET+LSPQ
Sbjct: 78 GNYFCSTKGQLFLWD--KTSNIVKIKVQELFQRPVLTASSFQPIEGGPVSLKCETRLSPQ 135
Query: 219 RPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQI 278
R DVQLQF FR++Q LG GWS SP LQI A+W+ED+GSYWC+ ETVTH I+K+SL+SQI
Sbjct: 136 RLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTGSYWCKAETVTHRIRKQSLQSQI 195
Query: 279 RVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRS 338
VQR+P+SNV+LEIR GGQ+ EG+ ++L+CSVA G+G VTFSW++E S+G+KTQRS
Sbjct: 196 HVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQRS 255
Query: 339 LLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGD 398
L AEL + VKESDAG+YYC ADN H PI S + + VRIPVS PVLT R+P A VGD
Sbjct: 256 LSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAVGD 315
Query: 399 LLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLG 458
LLELHCE+LRGSPPILY+FYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC+A+NGLG
Sbjct: 316 LLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNGLG 375
Query: 459 AQHSHGVSLRVTVP 472
AQ S V + ++ P
Sbjct: 376 AQCSEAVPVSISGP 389
Score = 263 bits (672), Expect = 4e-70
Identities = 192/510 (37%), Positives = 271/510 (53%), Gaps = 37/510 (7%)
Query: 199 STPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSY 258
S+ EG + L C+ + Q +Q + + +D++ L + + + I + DSG+Y
Sbjct: 26 SSVFEGDSIVLKCQGE---QNWKIQ-KMAYHKDNKELSV-FKKFSDFLIQSAVLSDSGNY 80
Query: 259 WCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLIC----SVAQG 314
+C + K S +I+VQ + V + + Q IEG + L C S +
Sbjct: 81 FCSTKGQLFLWDKTSNIVKIKVQELFQRPV---LTASSFQPIEGGPVSLKCETRLSPQRL 137
Query: 315 SGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRV 374
+ F + +E +V G + EL + V D G Y+C A+ V I ++
Sbjct: 138 DVQLQFCFFRENQVLGSGWSSS----PELQISAVWSEDTGSYWCKAETVTHRIRKQSLQS 193
Query: 375 TV---RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE--DVTLGNSSA 429
+ RIP+S+ L RAP G L L C G+ + + +Y E ++G +
Sbjct: 194 QIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAGGTGNVTFSWYREATGTSMGKKTQ 253
Query: 430 PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVV 489
S ++ +G Y C ADNG S V++ V +PVSRPVLTLR+PGAQA V
Sbjct: 254 RSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVNIPVRIPVSRPVLTLRSPGAQAAV 313
Query: 490 GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNG 549
GDLLELHCE+LRGS PILY FYHED TLGN SA SGGGASFNLSLT EHSGNYSCEA+NG
Sbjct: 314 GDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCEANNG 373
Query: 550 LGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSAT 609
LGAQ S+ V ++++G R L AG+ + +L A LL YA + G SAT
Sbjct: 374 LGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLGFTGVALLL-YALFHKISGESSAT 432
Query: 610 GTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPM-ELEPMYSNVNPGDSNPIYSQIWSI 668
EP + SR +PQE T+S P M EL+P+Y NV D + +YSQ+WS+
Sbjct: 433 ----------NEPRGA--SRPNPQEFTYSSPTPDMEELQPVYVNVGSVDVDVVYSQVWSM 480
Query: 669 QHTKENSANCPMMHQEHEELTVLYSELKKT 698
Q E+SAN + E+++ V+YS +KK+
Sbjct: 481 QQ-PESSANIRTL-LENKDSQVIYSSVKKS 508
Score = 82.8 bits (203), Expect = 1e-15
Identities = 95/390 (24%), Positives = 168/390 (43%), Gaps = 46/390 (11%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW LL+I EQ+ ++ L+ P S+ F+G+ + L C + Q Y
Sbjct: 1 MLLWSLLVIFDAVTEQAD----SLTLVAP--SSVFEGDSIVLKCQGEQNWKIQKMAYHKD 54
Query: 61 DEKLLKIKH------DKIQITEPGNYQCKTRG-----SSLSDAVHVE----FSPDWLILQ 105
+++L K +++ GNY C T+G S+ V ++ F L
Sbjct: 55 NKELSVFKKFSDFLIQSAVLSDSGNYFCSTKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
Query: 106 ALHPVFEGDNVILRCQGKDNKN----THQKVYYKDGKQLPNSYNLE-KITVNSV-SRDNS 159
+ P+ EG V L+C+ + + Q ++++ + L + ++ ++ +++V S D
Sbjct: 115 SFQPI-EGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSEDTG 173
Query: 160 KYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPV---LRASSSTPIEGSPMTLTCETQLS 216
Y C A + I S I VQ + + V +RA EG + L C S
Sbjct: 174 SYWCKAETVTH--RIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLC----S 227
Query: 217 PQRPDVQLQFSLFRDSQTLGLG----WSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKR 272
+ FS +R++ +G S S L+IPA+ D+G Y+C + I+ +
Sbjct: 228 VAGGTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSK 287
Query: 273 SLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
+ + R+PVS L +R G Q G+ + L C +GS + + ++ E +LG
Sbjct: 288 VVNIPV---RIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHED--VTLG 342
Query: 333 RKTQRSLLAELHVLTVKESDAGRYYCAADN 362
+ S L++ +G Y C A+N
Sbjct: 343 NSSAPSGGGASFNLSLTAEHSGNYSCEANN 372
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 452 bits (1163), Expect = e-127
Identities = 257/567 (45%), Positives = 332/567 (58%), Gaps = 11/567 (1%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW++LL+L P Q P+ ++ L PPW+T F+GE+V L C Q T WYH
Sbjct: 1 MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQ-KTKWYH 59
Query: 61 ---DEKLLKIKHDKI-QITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNV 116
+++L+ D I ++ E G Y+C+ +GS LS VH++FS LILQA VFEGD+V
Sbjct: 60 RYLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSV 119
Query: 117 ILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEV 176
+LRC+ K + +Y D + + ++ +DN Y CT Y++ V
Sbjct: 120 VLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCC---PV 176
Query: 177 TSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLG 236
+S + IQVQE F PVLRASS PI G+P+TLTCETQLS +R DV L+F FRD QTLG
Sbjct: 177 SSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLG 236
Query: 237 LGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
LGWS SP QI AMW++DSG YWC+ T+ +S+ S RS I+VQ +P S+ L + P
Sbjct: 237 LGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSPRSWIQVQ-IPASHPVLTLSPEK 295
Query: 297 GQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRY 356
EG + L C + S + ++ EG L K+ R ++ ++G Y
Sbjct: 296 ALNFEGTKVTLHCETQEDSLRTLYRFYHEG--VPLRHKSVRCERGASISFSLTTENSGNY 353
Query: 357 YCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYR 416
YC ADN S + ++V +PVSHPVL +P G + LHCE+ RGS PILY+
Sbjct: 354 YCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQ 413
Query: 417 FYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRP 476
F+HE L SA S GG + + SLTAEHSGNY C ADNG G Q S VSL VTVPVS P
Sbjct: 414 FHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHP 473
Query: 477 VLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTT 536
VLTL + A G + LHCE RGS ILY FYHED L + S S G SF+ SLT
Sbjct: 474 VLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTE 533
Query: 537 EHSGNYSCEADNGLGAQHSKVVTLNVT 563
HSGNY C ADNG G Q S+VV+L VT
Sbjct: 534 GHSGNYYCTADNGFGPQRSEVVSLFVT 560
Score = 420 bits (1079), Expect = e-117
Identities = 294/711 (41%), Positives = 383/711 (53%), Gaps = 70/711 (9%)
Query: 20 APKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHDKIQ------ 73
A VL L+P + F+G KV L C + SL + YH+ L+ K + +
Sbjct: 284 ASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRF-YHEGVPLRHKSVRCERGASIS 342
Query: 74 ----ITEPGNYQCKTR---GSSLSDAVHVEFSPDWLILQALHPV----------FEGDNV 116
GNY C G+ S AV + + + HPV FEG V
Sbjct: 343 FSLTTENSGNYYCTADNGLGAKPSKAVSLSVT-----VPVSHPVLNLSSPEDLIFEGAKV 397
Query: 117 ILRCQGKDNKNTHQKVYYKDGKQLP----NSYNLEKITVNSVSRDNSKYHCTAYRKFYIL 172
L C+ + ++ +G L NS I+ + + + Y+CTA F
Sbjct: 398 TLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCTADNGFG-- 455
Query: 173 DIEVTSKPLNIQVQELFLHPVLRASSSTPI--EGSPMTLTCETQLSPQRPDVQLQFSLFR 230
SK +++ V HPVL SS+ + EG+ +TL CE Q R Q+ + +
Sbjct: 456 --PQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQ----RGSPQILYQFYH 509
Query: 231 DSQTLGLGWSRSP----RLQIPAMWTED-SGSYWCEVETVTHSIKKRSLRSQIRVQRVPV 285
+ L WS S R+ TE SG+Y+C T + + VPV
Sbjct: 510 EDMPL---WSSSTPSVGRVSFSFSLTEGHSGNYYC---TADNGFGPQRSEVVSLFVTVPV 563
Query: 286 SNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHV 345
S L +R Q + G+ + L C +GS + + ++ E +LG + S
Sbjct: 564 SRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDV--TLGSSSAPSGGEASFN 621
Query: 346 LTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCE 405
L++ +G Y C A+N S I ++V +PVS P+LTFRAPRA VVGDLLELHCE
Sbjct: 622 LSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCE 681
Query: 406 SLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGV 465
+LRGS PILY FYHEDVTLG SAPSGGGASFNLSLT EHSG YSC+ADNGL AQ S V
Sbjct: 682 ALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMV 741
Query: 466 SLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSG 525
+L+V VPVSRPVLTLRAPG A VGDLLELHCE+LRGS ILY F+HED TLGN S+ S
Sbjct: 742 TLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSSPS- 800
Query: 526 GGASFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSIL 585
GGAS NLSLT EHSGNYSCEADNGLGAQ S+ VTL +TG + NR+G A G+ G +LSI
Sbjct: 801 GGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSIA 860
Query: 586 VLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPME 645
LAA A LL Y RK G A+ +P+ S PS D QEPT+ A E
Sbjct: 861 GLAAGALLL-YCWLSRKAGRKPAS-----------DPARS-PSDSDSQEPTYHNVPAWEE 907
Query: 646 LEPMYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELK 696
L+P+Y+N NP N +YS++ IQ K+++ H ++ ++YSE+K
Sbjct: 908 LQPVYTNANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVK 958
Score = 371 bits (953), Expect = e-102
Identities = 237/537 (44%), Positives = 308/537 (57%), Gaps = 36/537 (6%)
Query: 76 EPGNYQCKTRGSSLSDAVHVEFSPDWLILQ--ALHPV----------FEGDNVILRCQGK 123
+ G Y CK +++ +V + W+ +Q A HPV FEG V L C+ +
Sbjct: 254 DSGFYWCKA--ATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQ 311
Query: 124 DNKNTHQKVYYKDGKQLPN-SYNLEK---ITVNSVSRDNSKYHCTAYRKFYILDIEVTSK 179
++ +Y +G L + S E+ I+ + + ++ Y+CTA + S
Sbjct: 312 EDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSL 371
Query: 180 PLNIQVQELFLHPVLRASSSTPI--EGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGL 237
+ + V HPVL SS + EG+ +TL CE Q R + + + + L
Sbjct: 372 SVTVPVS----HPVLNLSSPEDLIFEGAKVTLHCEAQ----RGSLPILYQFHHEGAALER 423
Query: 238 GWSRSPR-LQIP-AMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPT 295
+ S + I ++ E SG+Y+C + + +++ + V PVS+ L +
Sbjct: 424 RSANSAGGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTV---PVSHPVLTLSSA 480
Query: 296 GGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGR 355
EG + L C V +GS + + ++ E L + S+ ++ E +G
Sbjct: 481 EALTFEGATVTLHCEVQRGSPQILYQFYHEDM--PLWSSSTPSVGRVSFSFSLTEGHSGN 538
Query: 356 YYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILY 415
YYC ADN P S + + V +PVS P+LT R PRA VVGDLLELHCE+ RGSPPILY
Sbjct: 539 YYCTADNGFGPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELHCEAPRGSPPILY 598
Query: 416 RFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSR 475
FYHEDVTLG+SSAPSGG ASFNLSLTAEHSGNYSC+A+NGL AQHS +SL V VPVSR
Sbjct: 599 WFYHEDVTLGSSSAPSGGEASFNLSLTAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSR 658
Query: 476 PVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLT 535
P+LT RAP AQAVVGDLLELHCE+LRGS PILYWFYHED TLG ISA SGGGASFNLSLT
Sbjct: 659 PILTFRAPRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLT 718
Query: 536 TEHSGNYSCEADNGLGAQHSKVVTLNV-TGTSRNRTGLTAAGITGLVLSILVLAAAA 591
TEHSG YSCEADNGL AQ S++VTL V SR L A G V +L L A
Sbjct: 719 TEHSGIYSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEA 775
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 344 bits (883), Expect = 1e-94
Identities = 172/279 (61%), Positives = 209/279 (74%), Gaps = 2/279 (0%)
Query: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253
L AS S P EGSP+TLTC+ Q D Q QF FRD++ LG GWS SP+LQI AMW E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313
D+GSYWCE +T+ + RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA
Sbjct: 80 DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373
G+G +TF W+K +L KTQRSL AE + +V+ESDA +YYC A+N + P S +
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433
+TVRIPVS P+L RAPRA V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVP 472
GASFNLSLT EHSGNYSC+A+NGLGAQ S V+L TVP
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 234 bits (598), Expect = 2e-61
Identities = 166/414 (40%), Positives = 219/414 (52%), Gaps = 34/414 (8%)
Query: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359
EG + L C + S F + R+LG S +L + + + D G Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
Query: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417
A + S +L S ++ V R+PV+ L + P + GD L L C G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468
Y V L S SLTAE+ + Y C A+NG G S VS+
Sbjct: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
Query: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588
SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN T + R+ +G+ +LS L A
Sbjct: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPA 320
Query: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648
A L Y +RK G SA ++P S PS + PQE T+ P +L+P
Sbjct: 321 TVALLFCYG-LKRKIGRRSA-----------RDPLRSLPSPL-PQEFTYLNSPTPGQLQP 367
Query: 649 MYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDD 702
+Y NVN + +YS + Q +E+ A H E + +YS L+K + D
Sbjct: 368 IYENVNVVSGDEVYSLAYYNQPEQESVAETLGTHMEDKVSLDIYSRLRKANITD 421
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 344 bits (883), Expect = 1e-94
Identities = 172/279 (61%), Positives = 209/279 (74%), Gaps = 2/279 (0%)
Query: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253
L AS S P EGSP+TLTC+ Q D Q QF FRD++ LG GWS SP+LQI AMW E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313
D+GSYWCE +T+ + RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA
Sbjct: 80 DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373
G+G +TF W+K +L KTQRSL AE + +V+ESDA +YYC A+N + P S +
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433
+TVRIPVS P+L RAPRA V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVP 472
GASFNLSLT EHSGNYSC+A+NGLGAQ S V+L TVP
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVP 297
Score = 231 bits (589), Expect = 2e-60
Identities = 166/415 (40%), Positives = 220/415 (53%), Gaps = 35/415 (8%)
Query: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359
EG + L C + S F + R+LG S +L + + + D G Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
Query: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417
A + S +L S ++ V R+PV+ L + P + GD L L C G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468
Y V L S SLTAE+ + Y C A+NG G S VS+
Sbjct: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
Query: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588
SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN T + R+ +G+ +LS L A
Sbjct: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPA 320
Query: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648
A L Y +RK G SA ++P S PS + PQE T+ P +L+P
Sbjct: 321 TVALLFCYG-LKRKIGRRSA-----------RDPLRSLPSPL-PQEFTYLNSPTPGQLQP 367
Query: 649 MYSNVNPGDSNPIYSQIWSIQHTKEN-SANCPMMHQEHEELTVLYSELKKTHPDD 702
+Y NVN + +YS + Q +E+ +A H E + +YS L+K + D
Sbjct: 368 IYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANITD 422
>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
Length = 366
Score = 340 bits (872), Expect = 3e-93
Identities = 170/277 (61%), Positives = 207/277 (74%), Gaps = 2/277 (0%)
Query: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253
L AS S P EGSP+TLTC+ Q D Q QF FRD++ LG GWS SP+LQI AMW E
Sbjct: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
Query: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313
D+GSYWCE +T+ + RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA
Sbjct: 80 DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
Query: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373
G+G +TF W+K +L KTQRSL AE + +V+ESDA +YYC A+N + P S +
Sbjct: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
Query: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433
+TVRIPVS P+L RAPRA V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
Query: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVT 470
GASFNLSLT EHSGNYSC+A+NGLGAQ S V+L T
Sbjct: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT 295
Score = 197 bits (502), Expect = 2e-50
Identities = 148/394 (37%), Positives = 190/394 (48%), Gaps = 76/394 (19%)
Query: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359
EG + L C + S F + R+LG S +L + + + D G Y+C
Sbjct: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
Query: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417
A + S +L S ++ V R+PV+ L + P + GD L L C G+ I + +
Sbjct: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
Query: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468
Y V L S SLTAE+ + Y C A+NG G S VS+
Sbjct: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
Query: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588
SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN TG
Sbjct: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTG------------------------ 296
Query: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648
RR ++P S PS + PQE T+ P +L+P
Sbjct: 297 -----------RR----------------SARDPLRSLPSPL-PQEFTYLNSPTPGQLQP 328
Query: 649 MYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMH 682
+Y N S ++ + QH+ E A P H
Sbjct: 329 IYENEPREQSVAVHGR---QQHSSEQKAQKPWGH 359
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 318 bits (815), Expect = 1e-86
Identities = 172/382 (45%), Positives = 234/382 (61%), Gaps = 9/382 (2%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW LL P QS A K V+ ++PPW+T FKGE+V L C+ A T WYH
Sbjct: 1 MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQF-YATEKTTWYH 59
Query: 61 ----DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNV 116
EKL + +++ E G Y+C+ RGS S+ V + FS D LILQA + VFEGD +
Sbjct: 60 RHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTL 119
Query: 117 ILRCQGKDNKNTHQKVYYKDGKQLP-NSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIE 175
+LRC + + Y +G L ++ + + + + S +N Y C Y D+
Sbjct: 120 VLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDEN--DVF 177
Query: 176 VTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL 235
++ + I++QELF HP L+A+ S P EG+ + L+CETQL P+R D L F+ FRD + +
Sbjct: 178 RSNFKI-IKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVI 236
Query: 236 GLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPT 295
WS P LQ+P +W E+SGSYWC ETV +I K S QI VQR+PVS V LE +P+
Sbjct: 237 LSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPS 296
Query: 296 GGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGR 355
GGQ +EGE +VL+CSVA+G+G TFSWH+E SLGRKTQRSL AEL + +++S AG
Sbjct: 297 GGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGG 356
Query: 356 YYCAADNVHSPILSTWIRVTVR 377
YYC ADN + P+ S + VTVR
Sbjct: 357 YYCTADNSYGPVQSMVLNVTVR 378
Score = 150 bits (380), Expect = 3e-36
Identities = 134/471 (28%), Positives = 215/471 (45%), Gaps = 52/471 (11%)
Query: 254 DSGSYWCEVETVTHSIKKRSL-RSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVA 312
+SG Y C+ S R L S + + P S + EG+ +VL C
Sbjct: 79 ESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYS------------VFEGDTLVLRCHRR 126
Query: 313 QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWI 372
+ + G + S+ K+ L+ + ++ G Y C + + +
Sbjct: 127 RKEKLTAVKYTWNGNILSISNKSWDLLIPQ-----ASSNNNGNYRCIGYGDENDVFRSNF 181
Query: 373 RVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESL----RGSPPILYRFYHE-DVTLGNS 427
++ ++I P +A + G+ + L CE+ R P+ + F+ + +V L +
Sbjct: 182 KI-IKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDW 240
Query: 428 SAPSGGGASFNLSLTA---EHSGNYSCDADNGLGAQHSHGVSLRVTV---PVSRPVLTLR 481
S L L E+SG+Y C A+ G H H SL++ V PVS +L +
Sbjct: 241 STYP------ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQ 294
Query: 482 APGAQAVVGDLLELHCESLRGSFPILYWFYHED--DTLGNISAHSGGGASFNLSLTTEHS 539
G QAV G++L L C G+ + ++ ED ++LG + S ++ H+
Sbjct: 295 PSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHA 354
Query: 540 GNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARA 599
G Y C ADN G S V+ + V T NR GL AAG TG +LS L+LA A LL +
Sbjct: 355 GGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVA--LLFHCWR 412
Query: 600 RRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSN 659
RRK G+ G + P P+ P E +HS A +EL+ +Y +V+P +
Sbjct: 413 RRK-SGVGFLGDETRLP-----PAPG------PGESSHSICPAQVELQSLYVDVHPKKGD 460
Query: 660 PIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSR 710
+YS+I + Q +E AN E ++++V+YSE+K HPD+SAG+ SS+
Sbjct: 461 LVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSK 511
>gi|50878302 Fc receptor-like B [Homo sapiens]
Length = 426
Score = 172 bits (435), Expect = 1e-42
Identities = 100/282 (35%), Positives = 152/282 (53%), Gaps = 13/282 (4%)
Query: 3 LWLL--LLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGD---TY 57
+W L LL+L P Q+ K +L L+PPW+T FKGE+V L C L + T
Sbjct: 1 MWPLTALLLLVPSSGQAATLEKPILSLHPPWTTIFKGERVTLKCDGYHPLLLELQPISTL 60
Query: 58 WYHDEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALH-PVFEGDNV 116
WY LL I++ PG Y+C+TRG+ +SD +H+ S DWLILQ + PVFEG+ +
Sbjct: 61 WYLGHLLLPSHKKSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPVFEGEPL 120
Query: 117 ILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITV-NSVSRDNSKYHCTAYRKFYILDIE 175
+LRC+G +K ++ YY DG+ + ++ TV + + D+ +Y C+ + +
Sbjct: 121 VLRCRGWYDKVVYKLHYYHDGQAVRYFHSSANYTVLQARASDSGRYQCSGTMRIPVESAP 180
Query: 176 VTSKPLNIQVQELFLHPVLRASSSTPIEGSPM---TLTCETQLSPQRPDVQLQFSLFRDS 232
+ S + + VQELF PVLR G+ + L C+T+L PQ+ D LQF+ ++ S
Sbjct: 181 MFSAKVAVTVQELFRAPVLRVMGPREARGAALGGVVLRCDTRLHPQKRDTPLQFAFYKYS 240
Query: 233 QTL-GLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRS 273
+ + W +P E+ SYWCE T T S++KRS
Sbjct: 241 RAVRRFDW--GAEYTVPEPEVEELESYWCEAATATRSVRKRS 280
Score = 33.5 bits (75), Expect = 0.72
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query: 285 VSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELH 344
VSN L ++ + EGE +VL C ++ +G+ + A
Sbjct: 100 VSNDWLILQVPYAPVFEGEPLVLRCRGWYDKVVYKLHYYHDGQAVRYFHSS-----ANYT 154
Query: 345 VLTVKESDAGRYYCAADN----VHSPILSTWIRVTVRIPVSHPVLTFRAPR 391
VL + SD+GRY C+ +P+ S + VTV+ PVL PR
Sbjct: 155 VLQARASDSGRYQCSGTMRIPVESAPMFSAKVAVTVQELFRAPVLRVMGPR 205
Score = 32.0 bits (71), Expect = 2.1
Identities = 50/233 (21%), Positives = 84/233 (36%), Gaps = 31/233 (13%)
Query: 290 LEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVK 349
L + P + +GE + L C G + + LG LL H +++
Sbjct: 25 LSLHPPWTTIFKGERVTLKCD---GYHPLLLELQPISTLWYLGH-----LLLPSHKKSIE 76
Query: 350 ESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRG 409
G Y C +P+ + + VS+ L + P A G+ L L C
Sbjct: 77 VQTPGVYRCQTRG--APVSDP-----IHLSVSNDWLILQVPYAPVFEGEPLVLRCRGWYD 129
Query: 410 SPPILYRFYHEDVTLGNSSAPSGGGASFN-LSLTAEHSGNYSCDADNGLGAQHSHGVSLR 468
+YH+ G + A++ L A SG Y C + + + S +
Sbjct: 130 KVVYKLHYYHD----GQAVRYFHSSANYTVLQARASDSGRYQCSGTMRIPVESAPMFSAK 185
Query: 469 VTVPVSR----PVLTLRAP--GAQAVVGDLLELHCES----LRGSFPILYWFY 511
V V V PVL + P A +G ++ L C++ + P+ + FY
Sbjct: 186 VAVTVQELFRAPVLRVMGPREARGAALGGVV-LRCDTRLHPQKRDTPLQFAFY 237
>gi|10835133 Fc fragment of IgG, high affinity Ia, receptor (CD64)
[Homo sapiens]
Length = 374
Score = 144 bits (363), Expect = 3e-34
Identities = 99/288 (34%), Positives = 147/288 (51%), Gaps = 18/288 (6%)
Query: 3 LWLL--LLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
+W L LL+ P Q KAV+ L PPW + F+ E V L C + H T W+
Sbjct: 1 MWFLTTLLLWVPVDGQVDTT-KAVITLQPPWVSVFQEETVTLHCE-VLHLPGSSSTQWFL 58
Query: 61 DEKLLKIKHDKIQIT-----EPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ + +IT + G Y+C+ S SD + +E WL+LQ VF EG+
Sbjct: 59 NGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGE 118
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVS-RDNSKYHCTAYRKFYILD 173
+ LRC +K + +YY++GK + +T+ + N YHC+ K
Sbjct: 119 PLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKH---- 174
Query: 174 IEVTSKPLNIQVQELFLHPVLRASSSTPI-EGSPMTLTCETQLSPQRPDVQLQFSLFRDS 232
TS +++ V+ELF PVL AS ++P+ EG+ +TL+CET+L QRP +QL FS + S
Sbjct: 175 -RYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGS 233
Query: 233 QTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRV 280
+TL G + S QI EDSG YWCE T ++ KRS +++V
Sbjct: 234 KTL-RGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQV 280
Score = 34.7 bits (78), Expect = 0.33
Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 44/241 (18%)
Query: 368 LSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLR--GSPPILYRFYHEDVTLG 425
L W+ V ++ + V+T + P + + LHCE L GS +
Sbjct: 7 LLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFL-------- 58
Query: 426 NSSAPSGGGASFNL-SLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPG 484
N +A S+ + S + SG Y C GL G S + + + R L L+
Sbjct: 59 NGTATQTSTPSYRITSASVNDSGEYRC--QRGLS-----GRSDPIQLEIHRGWLLLQVSS 111
Query: 485 AQAVVGDLLELHCESLRGS--FPILYW-------FYHEDDTLGNISAHSGGGASFNLSLT 535
G+ L L C + + + +LY+ F+H + L + N+S
Sbjct: 112 RVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKT--------NIS-- 161
Query: 536 TEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVL--SILVLAAAAAL 593
H+G Y C +G+G ++VT + A +T +L +++ L+ L
Sbjct: 162 --HNGTYHC---SGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKL 216
Query: 594 L 594
L
Sbjct: 217 L 217
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 133 bits (334), Expect = 7e-31
Identities = 94/266 (35%), Positives = 138/266 (51%), Gaps = 8/266 (3%)
Query: 101 WLILQAL-HPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVS-RDN 158
WL LQA +PVFEGD + LRCQG N Q +Y+DGK L S + +++ + + +
Sbjct: 19 WLYLQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATVQSR 78
Query: 159 SKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRA-SSSTPIEGSPMTLTCETQLSP 217
+Y C+ + TS+ +QVQELF PVL A S P EGS +TL C+T+L P
Sbjct: 79 GQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTKLHP 138
Query: 218 QRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQ 277
R ++L FS +D TL P L IP DSG YWCEV ++K+S + +
Sbjct: 139 LRSALRLLFSFHKDGHTL-QDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLE 197
Query: 278 IRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQR 337
+RVQ PVS L + G+ + L+C +GS + +S++ + ++ +G +
Sbjct: 198 VRVQ-APVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKI--VGNHSAP 254
Query: 338 SLLAELHVLTVK-ESDAGRYYCAADN 362
+ VK E DAG Y C A+N
Sbjct: 255 CGGTTSLLFPVKSEQDAGNYSCEAEN 280
Score = 122 bits (305), Expect = 2e-27
Identities = 120/435 (27%), Positives = 198/435 (45%), Gaps = 56/435 (12%)
Query: 299 LIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYC 358
+ EG+ + L C + + ++++G+ ++ Q + V G+Y C
Sbjct: 29 VFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFSKENQTLSMGAATV-----QSRGQYSC 83
Query: 359 AADNVHSPILSTWIRVTVRIPVSH----PVLTFRAPRAHTVVGDLLELHCES----LRGS 410
+ ++ P T T + V PVL+ P G L+ L C++ LR +
Sbjct: 84 SGQVMYIPQTFTQTSETAMVQVQELFPPPVLS-AIPSPEPREGSLVTLRCQTKLHPLRSA 142
Query: 411 PPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAE-HSGNYSCDA--DNGLGAQHSHGVSL 467
+L+ F H+D G++ G + E SG Y C+ + G + S + +
Sbjct: 143 LRLLFSF-HKD---GHTLQDRGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQKQSPQLEV 198
Query: 468 RVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGG 527
RV PVSRPVLTL A VGD+++L CE+ RGS PILY FY ++ +GN SA GG
Sbjct: 199 RVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGNHSAPCGGT 258
Query: 528 ASFNLSLTTEH-SGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSIL- 585
S + +E +GNYSCEA+N + + S+ L++ G+ T + + L S+L
Sbjct: 259 TSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKGSQVLFTPASNWLVPWLPASLLG 318
Query: 586 VLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPME 645
++ AAALL Y R+ RK G L PS+I P P E
Sbjct: 319 LMVIAAALLVYVRSWRKAGPL--------------------PSQIPPTAPGG-------E 351
Query: 646 LEPMYSNVN---PGDSNPIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDD 702
P+Y+NV+ D +YS + + +K + A ++ +++ +E++ P +
Sbjct: 352 QCPLYANVHHQKGKDEGVVYSVVH--RTSKRSEARSAEFTVGRKDSSIICAEVRCLQPSE 409
Query: 703 -SAGEASSRGRAHEE 716
S+ E + R R +E
Sbjct: 410 VSSTEVNMRSRTLQE 424
Score = 111 bits (278), Expect = 2e-24
Identities = 90/288 (31%), Positives = 136/288 (47%), Gaps = 41/288 (14%)
Query: 194 LRASSSTPIEGSPMTLTCE-------TQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQ 246
L+A + EG +TL C+ +Q+ R L FS +++QTL +G
Sbjct: 22 LQAWPNPVFEGDALTLRCQGWKNTPLSQVKFYRDGKFLHFS--KENQTLSMG-------- 71
Query: 247 IPAMWTEDSGSYWC--EVETVTHSIKKRSLRSQIRVQRV---PVSNVNLEIRPTGGQLIE 301
A + G Y C +V + + + S + ++VQ + PV + P G L+
Sbjct: 72 --AATVQSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLV- 128
Query: 302 GENMVLICSVA----QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYY 357
L C + + + FS+HK+G R EL + KE D+G Y+
Sbjct: 129 ----TLRCQTKLHPLRSALRLLFSFHKDGHTLQ-----DRGPHPELCIPGAKEGDSGLYW 179
Query: 358 C--AADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILY 415
C A + S + V V+ PVS PVLT A VGD+++L CE+ RGSPPILY
Sbjct: 180 CEVAPEGGQVQKQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILY 239
Query: 416 RFYHEDVTLGNSSAPSGGGASFNLSLTAEH-SGNYSCDADNGLGAQHS 462
FY ++ +GN SAP GG S + +E +GNYSC+A+N + + S
Sbjct: 240 SFYLDEKIVGNHSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERS 287
>gi|69885149 Fc receptor-like and mucin-like 1 [Homo sapiens]
Length = 376
Score = 124 bits (312), Expect = 2e-28
Identities = 83/219 (37%), Positives = 116/219 (52%), Gaps = 10/219 (4%)
Query: 69 HDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQA-LHPVFEGDNVILRCQGKDNKN 127
H + +T+ + + + S+ H+ S DWLILQ PVFEGD ++LRCQ +
Sbjct: 64 HTEDDLTDAREAGFQVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWP 123
Query: 128 THQKVYYKDGKQL-PNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQ 186
Q +Y+DG L P N E D+ YHC+ + I T+ + I VQ
Sbjct: 124 LTQVTFYRDGSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQ 183
Query: 187 ELFLHPVLRA-SSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDS---QTLGLGWSRS 242
ELF P+LRA S+ P GSPMTL+C+T+L QR +L FS ++D Q+ GL S
Sbjct: 184 ELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGL----S 239
Query: 243 PRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQ 281
QIP + SGSYWCE T + + K+S + +IRVQ
Sbjct: 240 SEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQ 278
Score = 58.2 bits (139), Expect = 3e-08
Identities = 59/200 (29%), Positives = 89/200 (44%), Gaps = 23/200 (11%)
Query: 380 VSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNL 439
VS+ L + P GDLL L C++ + P FY + LG P G F++
Sbjct: 92 VSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALG----PPGPNREFSI 147
Query: 440 SLTAE-HSGNYSCDA---DNGLGAQHSHGVSLRVTVPVSRPVLTLRA-PGAQAVVGDLLE 494
++ + SG+Y C G G + V + +TV P LRA P A+ G +
Sbjct: 148 TVVQKADSGHYHCSGIFQSPGPGIPETASV-VAITVQELFPAPILRAVPSAEPQAGSPMT 206
Query: 495 LHCES----LRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTE-HSGNYSCEA--- 546
L C++ R + +L+ FY + G I G + F + +E HSG+Y CEA
Sbjct: 207 LSCQTKLPLQRSAARLLFSFYKD----GRIVQSRGLSSEFQIPTASEDHSGSYWCEAATE 262
Query: 547 DNGLGAQHSKVVTLNVTGTS 566
DN + Q S + + V G S
Sbjct: 263 DNQVWKQ-SPQLEIRVQGAS 281
Score = 38.1 bits (87), Expect = 0.029
Identities = 47/207 (22%), Positives = 85/207 (41%), Gaps = 20/207 (9%)
Query: 178 SKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGL 237
S+P ++ V +L +L+ + EG + L C Q P Q+ F +RD LG
Sbjct: 85 SEPFHLIVSYDWL--ILQGPAKPVFEGDLLVLRC--QAWQDWPLTQVTF--YRDGSALGP 138
Query: 238 GWSRSPRLQIPAMWTEDSGSYWCE--VETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPT 295
+ I + DSG Y C ++ I + + I VQ + + + +
Sbjct: 139 P-GPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSA 197
Query: 296 GGQLIEGENMVLICS----VAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKES 351
Q G M L C + + + + FS++K+GR+ R L +E + T E
Sbjct: 198 EPQA--GSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQ-----SRGLSSEFQIPTASED 250
Query: 352 DAGRYYCAADNVHSPILSTWIRVTVRI 378
+G Y+C A + + ++ +R+
Sbjct: 251 HSGSYWCEAATEDNQVWKQSPQLEIRV 277
>gi|110347451 platelet/endothelial cell adhesion molecule [Homo
sapiens]
Length = 738
Score = 111 bits (277), Expect = 3e-24
Identities = 168/769 (21%), Positives = 301/769 (39%), Gaps = 129/769 (16%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALIC----SSISHSLAQGDT 56
+LL LLL G+E S + P W T G+ + L C S+ SH Q
Sbjct: 15 VLLTLLLCSSLEGQENSFTINSVDMKSLPDW-TVQNGKNLTLQCFADVSTTSHVKPQHQM 73
Query: 57 YWYHDEKLL----KIKHDK------IQITEPGNYQCKT-----RGSSLSDAVHVEFSPDW 101
+Y D+ L +K + ++I + G Y+C ++ + VE P
Sbjct: 74 LFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQLLVEGVPSP 133
Query: 102 LILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKY 161
+ +G V + C + K P + +EK+ +N +
Sbjct: 134 RVTLDKKEAIQGGIVRVNCSVPEEK-------------APIHFTIEKLELNEKMVKLKRE 180
Query: 162 HCTAYRKFYILDIEV-------------------------TSKPLNIQVQELFLHPVLRA 196
+ + F IL+ V ++K + V E F P
Sbjct: 181 KNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHI 240
Query: 197 SSSTPI-EGSPMTLTCE---TQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWT 252
S + I EG+ + + C T L+ + P++ +Q +D + + +
Sbjct: 241 SPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQ----KDKAIVAHNRHGNKAVYSVMAMV 296
Query: 253 EDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNL----EIRPTGGQLIEGENMVLI 308
E SG+Y C+VE+ S +V + V+ L E+ + L +GE + L
Sbjct: 297 EHSGNYTCKVESSRIS----------KVSSIVVNITELFSKPELESSFTHLDQGERLNLS 346
Query: 309 CSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPIL 368
CS+ G+ F+ KE + S + + +SD+G Y C A
Sbjct: 347 CSIP-GAPPANFTIQKEDTIVSQTQDFTK---------IASKSDSGTYICTAGIDKVVKK 396
Query: 369 STWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSS 428
S +++ V +S P +++ A + + G +E+ CES+ G+ PI Y+ L NS+
Sbjct: 397 SNTVQIVVCEMLSQPRISYDA-QFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENST 455
Query: 429 APSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHG------VSLRVTVPVSRPVLTLRA 482
S A F + T + Y C ADN HSH + ++V PV +++ +
Sbjct: 456 KNSNDPAVFKDNPTED--VEYQCVADN----CHSHAKMLSEVLRVKVIAPVDEVQISILS 509
Query: 483 PGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASF--NLSLTTEHSG 540
G+ + L C GS PI Y FY E + S +F + E G
Sbjct: 510 -SKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEG 568
Query: 541 NYSC----EADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHY 596
Y C A++ SK++T+ V + + GL A I G+++++L++AA L
Sbjct: 569 EYYCTAFNRANHASSVPRSKILTVRVI-LAPWKKGLIAVVIIGVIIALLIIAAKCYFLRK 627
Query: 597 ARARRKPGGLS--ATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVN 654
A+A++ P +S A + + + +P+ S H+ + ++P+ N
Sbjct: 628 AKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYG-----HNDDVRNHAMKPINDNKE 682
Query: 655 PGDSNPIYSQIWSIQHTKENSANCPMMHQE--HEELTVLYSELKKTHPD 701
P +S+ Y+++ + H++ ++ +YSE++K PD
Sbjct: 683 PLNSDVQYTEV---------QVSSAESHKDLGKKDTETVYSEVRKAVPD 722
>gi|4503675 Fc fragment of IgE, high affinity I, receptor for; alpha
polypeptide precursor [Homo sapiens]
Length = 257
Score = 102 bits (254), Expect = 1e-21
Identities = 67/191 (35%), Positives = 101/191 (52%), Gaps = 13/191 (6%)
Query: 2 LLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHD 61
LL + LL P + V K + LNPPW+ FKGE V L C+ ++ T W+H+
Sbjct: 10 LLCVALLFFAPDGVLA-VPQKPKVSLNPPWNRIFKGENVTLTCNG-NNFFEVSSTKWFHN 67
Query: 62 EKLLKIKHDKIQIT-----EPGNYQCKTRGSSLSDAVHVEFSPDWLILQA-LHPVFEGDN 115
L + + + I + G Y+C+ + + S+ V++E DWL+LQA V EG
Sbjct: 68 GSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQP 127
Query: 116 VILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITV-NSVSRDNSKYHCTAYRKFYILDI 174
+ LRC G N + ++ +YYKDG+ L Y I++ N+ D+ Y+CT K + LD
Sbjct: 128 LFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTG--KVWQLDY 185
Query: 175 EVTSKPLNIQV 185
E S+PLNI V
Sbjct: 186 E--SEPLNITV 194
Score = 47.8 bits (112), Expect = 4e-05
Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 21/166 (12%)
Query: 95 VEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSV 154
V +P W + +F+G+NV L C G + ++ +G L N VN+
Sbjct: 32 VSLNPPW------NRIFKGENVTLTCNGNNFFEVSSTKWFHNGS-LSEETNSSLNIVNAK 84
Query: 155 SRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQ 214
D+ +Y C + S+P+ ++V +L +L+AS+ +EG P+ L C
Sbjct: 85 FEDSGEYKCQHQQVN-------ESEPVYLEVFSDWL--LLQASAEVVMEGQPLFLRCHGW 135
Query: 215 LSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWC 260
+ DV + ++D + L W + + I EDSG+Y+C
Sbjct: 136 ---RNWDVY-KVIYYKDGEALKY-WYENHNISITNATVEDSGTYYC 176
Score = 33.5 bits (75), Expect = 0.72
Identities = 38/165 (23%), Positives = 60/165 (36%), Gaps = 23/165 (13%)
Query: 290 LEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVK 349
+ + P ++ +GEN+ L C+ + W G SL +T S L+++ K
Sbjct: 32 VSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNG---SLSEETNSS----LNIVNAK 84
Query: 350 ESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRG 409
D+G Y C V+ V + V L +A + G L L C R
Sbjct: 85 FEDSGEYKCQHQQVNE-------SEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRN 137
Query: 410 SPPILYRFYHEDVTLGNSSAPSGGGASFNLSL---TAEHSGNYSC 451
+Y + A + N+S+ T E SG Y C
Sbjct: 138 WDVYKVIYYKD------GEALKYWYENHNISITNATVEDSGTYYC 176
>gi|50511926 Fc fragment of IgG, low affinity IIb, receptor isoform
3 [Homo sapiens]
Length = 291
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/193 (31%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW +L L P PKAVL L P W + + V L C +HS W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRG-THSPESDSIQWFH 86
Query: 61 DEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F EG+
Sbjct: 87 NGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 146
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYILD 173
++LRC +K + ++++GK S + ++ + +S YHCT + +
Sbjct: 147 TIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTL-- 204
Query: 174 IEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 205 --YSSKPVTITVQ 215
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/205 (22%), Positives = 78/205 (38%), Gaps = 19/205 (9%)
Query: 398 DLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGL 457
D + L C +++H + + PS + SG Y+C
Sbjct: 65 DSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANNNDSGEYTCQTGQT- 118
Query: 458 GAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTL 517
+S V + V L L+ P + G+ + L C S + + F+
Sbjct: 119 ------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN---- 168
Query: 518 GNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAG 576
G S +F++ HSG+Y C + G SK VT+ V S + G+ A
Sbjct: 169 GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAV 228
Query: 577 ITGLVLSILVLAAAAALLHYARARR 601
+TG+ ++ +V AA L Y R +R
Sbjct: 229 VTGIAVAAIV--AAVVALIYCRKKR 251
Score = 37.0 bits (84), Expect = 0.066
Identities = 46/211 (21%), Positives = 83/211 (39%), Gaps = 37/211 (17%)
Query: 188 LFLHPVLRASSSTP-------------IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQT 234
LFL PV ++ P ++ +TLTC SP+ +Q F +
Sbjct: 35 LFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQW----FHNGNL 90
Query: 235 LGLGWSRSPRLQIPAMWTEDSGSYWCEV-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIR 293
+ S R + DSG Y C+ +T ++ S+ V + P +LE +
Sbjct: 91 IPTHTQPSYRFKAN---NNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ 143
Query: 294 PTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDA 353
EGE +VL C + V ++ + G+ + R + + + S +
Sbjct: 144 -------EGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQAN-----HSHS 191
Query: 354 GRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
G Y+C + ++ S + +TV+ P S P+
Sbjct: 192 GDYHCTGNIGYTLYSSKPVTITVQAPSSSPM 222
>gi|50511930 Fc fragment of IgG, low affinity IIb, receptor isoform
1 [Homo sapiens]
Length = 310
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/193 (31%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW +L L P PKAVL L P W + + V L C +HS W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRG-THSPESDSIQWFH 86
Query: 61 DEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F EG+
Sbjct: 87 NGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 146
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYILD 173
++LRC +K + ++++GK S + ++ + +S YHCT + +
Sbjct: 147 TIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTL-- 204
Query: 174 IEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 205 --YSSKPVTITVQ 215
Score = 52.8 bits (125), Expect = 1e-06
Identities = 56/241 (23%), Positives = 92/241 (38%), Gaps = 29/241 (12%)
Query: 398 DLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGL 457
D + L C +++H + + PS + SG Y+C
Sbjct: 65 DSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANNNDSGEYTCQTGQT- 118
Query: 458 GAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTL 517
+S V + V L L+ P + G+ + L C S + + F+
Sbjct: 119 ------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN---- 168
Query: 518 GNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAG 576
G S +F++ HSG+Y C + G SK VT+ V S + G+ A
Sbjct: 169 GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAV 228
Query: 577 ITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPT 636
+TG+ ++ +V AA L Y R +R +SA EC+E + P + P PT
Sbjct: 229 VTGIAVAAIV--AAVVALIYCRKKR----ISAL----PGYPECREMGETLPEK--PANPT 276
Query: 637 H 637
+
Sbjct: 277 N 277
Score = 37.0 bits (84), Expect = 0.066
Identities = 46/211 (21%), Positives = 83/211 (39%), Gaps = 37/211 (17%)
Query: 188 LFLHPVLRASSSTP-------------IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQT 234
LFL PV ++ P ++ +TLTC SP+ +Q F +
Sbjct: 35 LFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQW----FHNGNL 90
Query: 235 LGLGWSRSPRLQIPAMWTEDSGSYWCEV-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIR 293
+ S R + DSG Y C+ +T ++ S+ V + P +LE +
Sbjct: 91 IPTHTQPSYRFKAN---NNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ 143
Query: 294 PTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDA 353
EGE +VL C + V ++ + G+ + R + + + S +
Sbjct: 144 -------EGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQAN-----HSHS 191
Query: 354 GRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
G Y+C + ++ S + +TV+ P S P+
Sbjct: 192 GDYHCTGNIGYTLYSSKPVTITVQAPSSSPM 222
>gi|126116592 Fc fragment of IgG, low affinity IIc, receptor [Homo
sapiens]
Length = 323
Score = 95.1 bits (235), Expect = 2e-19
Identities = 60/193 (31%), Positives = 91/193 (47%), Gaps = 12/193 (6%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW +L L P PKAVL L P W + + V L C +HS W+H
Sbjct: 28 MLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRG-THSPESDSIPWFH 86
Query: 61 DEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F EG+
Sbjct: 87 NGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 146
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYILD 173
++LRC +K + ++++GK S + ++ + +S YHCT + +
Sbjct: 147 TIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTL-- 204
Query: 174 IEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 205 --YSSKPVTITVQ 215
Score = 52.8 bits (125), Expect = 1e-06
Identities = 58/253 (22%), Positives = 96/253 (37%), Gaps = 28/253 (11%)
Query: 430 PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVV 489
P+ S+ SG Y+C +S V + V L L+ P +
Sbjct: 92 PTHTQPSYRFKANNNDSGEYTCQTGQT-------SLSDPVHLTVLSEWLVLQTPHLEFQE 144
Query: 490 GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTE-HSGNYSCEADN 548
G+ + L C S + + F+ G S +F++ HSG+Y C +
Sbjct: 145 GETIVLRCHSWKDKPLVKVTFFQN----GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNI 200
Query: 549 GLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSA 608
G SK VT+ V S + G+ A +TG+ ++ +V AA L Y R +R +SA
Sbjct: 201 GYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIV--AAVVALIYCRKKR----ISA 254
Query: 609 TGTSSHSPSECQEPSSSRPS--RIDPQEPTHSKPLAPMELEPMYSNVNP----GDSNPIY 662
T ++ + P + + P+E + A + Y +NP D IY
Sbjct: 255 NSTDPVKAAQFEPPGRQMIAIRKRQPEETNNDYETA----DGGYMTLNPRAPTDDDKNIY 310
Query: 663 SQIWSIQHTKENS 675
+ H N+
Sbjct: 311 LTLPPNDHVNSNN 323
Score = 34.7 bits (78), Expect = 0.33
Identities = 45/211 (21%), Positives = 82/211 (38%), Gaps = 37/211 (17%)
Query: 188 LFLHPVLRASSSTP-------------IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQT 234
LFL PV ++ P ++ +TLTC SP+ + F +
Sbjct: 35 LFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPW----FHNGNL 90
Query: 235 LGLGWSRSPRLQIPAMWTEDSGSYWCEV-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIR 293
+ S R + DSG Y C+ +T ++ S+ V + P +LE +
Sbjct: 91 IPTHTQPSYRFKAN---NNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ 143
Query: 294 PTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDA 353
EGE +VL C + V ++ + G+ + R + + + S +
Sbjct: 144 -------EGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQAN-----HSHS 191
Query: 354 GRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
G Y+C + ++ S + +TV+ P S P+
Sbjct: 192 GDYHCTGNIGYTLYSSKPVTITVQAPSSSPM 222
>gi|210031822 Fc fragment of IgG, low affinity IIa, receptor isoform
1 [Homo sapiens]
Length = 317
Score = 93.2 bits (230), Expect = 8e-19
Identities = 61/196 (31%), Positives = 93/196 (47%), Gaps = 17/196 (8%)
Query: 3 LWLL-----LLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTY 57
LWLL LL+L Q+ PKAVL L PPW + + V L C + S
Sbjct: 16 LWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQG-ARSPESDSIQ 74
Query: 58 WYHDEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF- 111
W+H+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F
Sbjct: 75 WFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ 134
Query: 112 EGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFY 170
EG+ ++LRC +K + ++++GK S+ ++ + +S YHCT +
Sbjct: 135 EGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYT 194
Query: 171 ILDIEVTSKPLNIQVQ 186
+ +SKP+ I VQ
Sbjct: 195 LF----SSKPVTITVQ 206
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/246 (21%), Positives = 94/246 (38%), Gaps = 32/246 (13%)
Query: 384 VLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTA 443
VL P + + D + L C+ R +++H + + PS +
Sbjct: 42 VLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 96
Query: 444 EHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGS 503
SG Y+C +S V + V L L+ P + G+ + L C S +
Sbjct: 97 NDSGEYTCQTGQT-------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDK 149
Query: 504 FPILYWFYHEDDTLGNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNV 562
+ F+ G S +F++ HSG+Y C + G SK VT+ V
Sbjct: 150 PLVKVTFFQN----GKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITV 205
Query: 563 TGTSRNRTGLTAAGITGLVLSILVLAAAAAL------LHYARARRKPGGLSATGTSSHSP 616
S + ++ G+++++++ A AA+ L Y R +R +SA T
Sbjct: 206 QVPS-----MGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKR----ISANSTDPVKA 256
Query: 617 SECQEP 622
++ + P
Sbjct: 257 AQFEPP 262
Score = 31.6 bits (70), Expect = 2.8
Identities = 37/179 (20%), Positives = 72/179 (40%), Gaps = 24/179 (13%)
Query: 202 IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCE 261
++ +TLTC+ SP+ +Q F + + S R + DSG Y C+
Sbjct: 53 LQEDSVTLTCQGARSPESDSIQW----FHNGNLIPTHTQPSYRFKAN---NNDSGEYTCQ 105
Query: 262 V-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTF 320
+T ++ S+ V + P +LE + EGE ++L C + V
Sbjct: 106 TGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ-------EGETIMLRCHSWKDKPLVKV 154
Query: 321 SWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIP 379
++ + G+ + L + S +G Y+C + ++ S + +TV++P
Sbjct: 155 TFFQNGKSQKFSH-----LDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVP 208
>gi|50511928 Fc fragment of IgG, low affinity IIb, receptor isoform
4 [Homo sapiens]
Length = 309
Score = 91.7 bits (226), Expect = 2e-18
Identities = 60/193 (31%), Positives = 92/193 (47%), Gaps = 13/193 (6%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW +L L P + PKAVL L P W + + V L C +HS W+H
Sbjct: 28 MLLWTAVLFLAPVAG-TPAPPKAVLKLEPQWINVLQEDSVTLTCRG-THSPESDSIQWFH 85
Query: 61 DEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F EG+
Sbjct: 86 NGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 145
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYILD 173
++LRC +K + ++++GK S + ++ + +S YHCT + +
Sbjct: 146 TIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTL-- 203
Query: 174 IEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 204 --YSSKPVTITVQ 214
Score = 52.8 bits (125), Expect = 1e-06
Identities = 56/241 (23%), Positives = 92/241 (38%), Gaps = 29/241 (12%)
Query: 398 DLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGL 457
D + L C +++H + + PS + SG Y+C
Sbjct: 64 DSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANNNDSGEYTCQTGQT- 117
Query: 458 GAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTL 517
+S V + V L L+ P + G+ + L C S + + F+
Sbjct: 118 ------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN---- 167
Query: 518 GNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAG 576
G S +F++ HSG+Y C + G SK VT+ V S + G+ A
Sbjct: 168 GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAV 227
Query: 577 ITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPT 636
+TG+ ++ +V AA L Y R +R +SA EC+E + P + P PT
Sbjct: 228 VTGIAVAAIV--AAVVALIYCRKKR----ISAL----PGYPECREMGETLPEK--PANPT 275
Query: 637 H 637
+
Sbjct: 276 N 276
Score = 35.8 bits (81), Expect = 0.15
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 24/184 (13%)
Query: 202 IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCE 261
++ +TLTC SP+ +Q F + + S R + DSG Y C+
Sbjct: 61 LQEDSVTLTCRGTHSPESDSIQW----FHNGNLIPTHTQPSYRFKAN---NNDSGEYTCQ 113
Query: 262 V-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTF 320
+T ++ S+ V + P +LE + EGE +VL C + V
Sbjct: 114 TGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ-------EGETIVLRCHSWKDKPLVKV 162
Query: 321 SWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
++ + G+ + R + + + S +G Y+C + ++ S + +TV+ P
Sbjct: 163 TFFQNGKSKKFSRSDPNFSIPQAN-----HSHSGDYHCTGNIGYTLYSSKPVTITVQAPS 217
Query: 381 SHPV 384
S P+
Sbjct: 218 SSPM 221
>gi|50511932 Fc fragment of IgG, low affinity IIb, receptor isoform
2 [Homo sapiens]
Length = 290
Score = 91.7 bits (226), Expect = 2e-18
Identities = 60/193 (31%), Positives = 92/193 (47%), Gaps = 13/193 (6%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
MLLW +L L P + PKAVL L P W + + V L C +HS W+H
Sbjct: 28 MLLWTAVLFLAPVAG-TPAPPKAVLKLEPQWINVLQEDSVTLTCRG-THSPESDSIQWFH 85
Query: 61 DEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F EG+
Sbjct: 86 NGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 145
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYILD 173
++LRC +K + ++++GK S + ++ + +S YHCT + +
Sbjct: 146 TIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTL-- 203
Query: 174 IEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 204 --YSSKPVTITVQ 214
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/205 (22%), Positives = 78/205 (38%), Gaps = 19/205 (9%)
Query: 398 DLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGL 457
D + L C +++H + + PS + SG Y+C
Sbjct: 64 DSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPS-----YRFKANNNDSGEYTCQTGQT- 117
Query: 458 GAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTL 517
+S V + V L L+ P + G+ + L C S + + F+
Sbjct: 118 ------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQN---- 167
Query: 518 GNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAG 576
G S +F++ HSG+Y C + G SK VT+ V S + G+ A
Sbjct: 168 GKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAV 227
Query: 577 ITGLVLSILVLAAAAALLHYARARR 601
+TG+ ++ +V AA L Y R +R
Sbjct: 228 VTGIAVAAIV--AAVVALIYCRKKR 250
Score = 35.8 bits (81), Expect = 0.15
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 24/184 (13%)
Query: 202 IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCE 261
++ +TLTC SP+ +Q F + + S R + DSG Y C+
Sbjct: 61 LQEDSVTLTCRGTHSPESDSIQW----FHNGNLIPTHTQPSYRFKAN---NNDSGEYTCQ 113
Query: 262 V-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTF 320
+T ++ S+ V + P +LE + EGE +VL C + V
Sbjct: 114 TGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ-------EGETIVLRCHSWKDKPLVKV 162
Query: 321 SWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
++ + G+ + R + + + S +G Y+C + ++ S + +TV+ P
Sbjct: 163 TFFQNGKSKKFSRSDPNFSIPQAN-----HSHSGDYHCTGNIGYTLYSSKPVTITVQAPS 217
Query: 381 SHPV 384
S P+
Sbjct: 218 SSPM 221
>gi|50511936 Fc fragment of IgG, low affinity IIa, receptor isoform
2 [Homo sapiens]
Length = 316
Score = 90.9 bits (224), Expect = 4e-18
Identities = 59/195 (30%), Positives = 92/195 (47%), Gaps = 16/195 (8%)
Query: 3 LWLL----LLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYW 58
LWLL +L+L + PKAVL L PPW + + V L C + S W
Sbjct: 16 LWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLTCQG-ARSPESDSIQW 74
Query: 59 YHDEKLLKIKHD-----KIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-E 112
+H+ L+ K + G Y C+T +SLSD VH+ +WL+LQ H F E
Sbjct: 75 FHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQE 134
Query: 113 GDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNS-KYHCTAYRKFYI 171
G+ ++LRC +K + ++++GK S+ ++ + +S YHCT + +
Sbjct: 135 GETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTL 194
Query: 172 LDIEVTSKPLNIQVQ 186
+SKP+ I VQ
Sbjct: 195 F----SSKPVTITVQ 205
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/246 (21%), Positives = 94/246 (38%), Gaps = 32/246 (13%)
Query: 384 VLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTA 443
VL P + + D + L C+ R +++H + + PS +
Sbjct: 41 VLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPS-----YRFKANN 95
Query: 444 EHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGS 503
SG Y+C +S V + V L L+ P + G+ + L C S +
Sbjct: 96 NDSGEYTCQTGQT-------SLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDK 148
Query: 504 FPILYWFYHEDDTLGNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNV 562
+ F+ G S +F++ HSG+Y C + G SK VT+ V
Sbjct: 149 PLVKVTFFQN----GKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITV 204
Query: 563 TGTSRNRTGLTAAGITGLVLSILVLAAAAAL------LHYARARRKPGGLSATGTSSHSP 616
S + ++ G+++++++ A AA+ L Y R +R +SA T
Sbjct: 205 QVPS-----MGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKR----ISANSTDPVKA 255
Query: 617 SECQEP 622
++ + P
Sbjct: 256 AQFEPP 261
Score = 31.6 bits (70), Expect = 2.8
Identities = 37/179 (20%), Positives = 72/179 (40%), Gaps = 24/179 (13%)
Query: 202 IEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCE 261
++ +TLTC+ SP+ +Q F + + S R + DSG Y C+
Sbjct: 52 LQEDSVTLTCQGARSPESDSIQW----FHNGNLIPTHTQPSYRFKAN---NNDSGEYTCQ 104
Query: 262 V-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTF 320
+T ++ S+ V + P +LE + EGE ++L C + V
Sbjct: 105 TGQTSLSDPVHLTVLSEWLVLQTP----HLEFQ-------EGETIMLRCHSWKDKPLVKV 153
Query: 321 SWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIP 379
++ + G+ + L + S +G Y+C + ++ S + +TV++P
Sbjct: 154 TFFQNGKSQKFSH-----LDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVP 207
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 87.8 bits (216), Expect = 3e-17
Identities = 140/564 (24%), Positives = 225/564 (39%), Gaps = 76/564 (13%)
Query: 33 TAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHD-------------KIQITEPGN 79
TA V+L C +H + WY D + L + + + ++++ G
Sbjct: 1757 TAILNSSVSLPCDVHAHP--NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM 1814
Query: 80 YQCKTRGSSLSDAVHVEFSPDWLILQALHP----------VFEGDNVILRCQGKDNKNTH 129
Y C+ ++ D V+ S L+ A V GD +L C+ D
Sbjct: 1815 YTCEALNAAGRDQKLVQLSV--LVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TDALPEP 1871
Query: 130 QKVYYKDGKQLPNSYNLE--------KITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPL 181
+YKDG+ L + + +I VS D Y C + V + L
Sbjct: 1872 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-DKGLYSCKVSN---VAGEAVRTFTL 1927
Query: 182 NIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSR 241
+QV F +P + + + + GSP+ LTC+ P L+ + +S + SR
Sbjct: 1928 TVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR 1985
Query: 242 SPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE 301
RLQ+ + +G+Y C E +K + + + R+ S V E ++E
Sbjct: 1986 GGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVARE-----HHVLE 2040
Query: 302 GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLL-----AELHVLTVKESDAGRY 356
G+ + L C A G +W K+G LG+ L L + ++ SDAG Y
Sbjct: 2041 GQEVRLDCE-ADGQPPPDVAWLKDG--SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2097
Query: 357 YCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVV---GDLLELHCESLRGSPPI 413
C A H+P TV + V P + A + T+V G+L+ + C +RGSPPI
Sbjct: 2098 TCVA---HNPAGEDARLHTVNVLVP-PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPI 2152
Query: 414 LYRFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCDADNGLGAQHSHGVSLRVT 470
+ + + L S G G + +S + +G ++C A + G +L+V
Sbjct: 2153 HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVA-DRNFTLQVQ 2211
Query: 471 VPVSRPVLTLRAPGAQAVV--GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
VP PVL VV G L+EL CE+ P++ W + L S G
Sbjct: 2212 VP---PVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLL---SQSLEQGP 2265
Query: 529 SFNL-SLTTEHSGNYSCEADNGLG 551
S L ++ SG YSC A + G
Sbjct: 2266 SLQLEAVGAGDSGTYSCVAVSEAG 2289
Score = 82.4 bits (202), Expect = 1e-15
Identities = 90/357 (25%), Positives = 138/357 (38%), Gaps = 34/357 (9%)
Query: 205 SPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVET 264
+P+ LTC + P + ++ G S S L+I +G Y C
Sbjct: 2681 APVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN 2740
Query: 265 VTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHK 324
K + VQ PV ++ P+ + + E ++L C A G T +W K
Sbjct: 2741 SAGVAHKHVF---LTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPTITWQK 2792
Query: 325 EGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
EG + G TQ +L + DAG Y C A N + R+ V++P PV
Sbjct: 2793 EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PV 2848
Query: 385 LTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAP-SGGGASFNL---- 439
+ P T G L C++ RGSP ++T P SG F +
Sbjct: 2849 IENGLPDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSG 2900
Query: 440 -----SLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLE 494
+L + +G Y+C A+N +G V L + V PV T +GD L
Sbjct: 2901 ELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILV---LPVFTTLPGDRSLRLGDRLW 2956
Query: 495 LHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNGLG 551
L C + P + W ++ +S GG +++ E SG Y C A+N +G
Sbjct: 2957 LRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Score = 70.1 bits (170), Expect = 7e-12
Identities = 147/601 (24%), Positives = 241/601 (40%), Gaps = 90/601 (14%)
Query: 67 IKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPV-FEGDNVILR------ 119
++ K+Q+ + G + C +S + F+ + L PV F+ D V++R
Sbjct: 2178 LRISKVQLADAGIFTCVA--ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2235
Query: 120 -CQGKDNKNTHQKVYYKDGKQLPNSYNLEK---ITVNSVSR-DNSKYHCTAY-------R 167
C+ + + KDG+ L S +LE+ + + +V D+ Y C A R
Sbjct: 2236 PCEAR-GVPLPLVSWMKDGEPLL-SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARR 2293
Query: 168 KFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFS 227
F + +E + Q EL L P G+PM L C+ Q +PQ P++ +
Sbjct: 2294 HFQLTVMEPPHIEDSGQPTELSLTP-----------GAPMELLCDAQGTPQ-PNI----T 2337
Query: 228 LFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSN 287
+D Q L + S ++ + D+G Y C E+ +I+K ++RVQ P N
Sbjct: 2338 WHKDGQALTRLENNSRATRV--LRVRDAGLYTCLAESPAGAIEK---SFRVRVQAPP--N 2390
Query: 288 VNLEIRPTGGQLIEG---ENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQ---RSLLA 341
+ + P G + + G +VL CSV + +WH++G V TQ R
Sbjct: 2391 I---VGPRGPRFVVGLAPGQLVLECSV-EAEPAPKITWHRDGIVLQEDAHTQFPERGRFL 2446
Query: 342 ELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRA--PRAHTVVGDL 399
+L L+ +D+G Y C A N ST + V I H V T R+ P + V
Sbjct: 2447 QLQALST--ADSGDYSCTARNAAG---STSVAFRVEI---HTVPTIRSGPPAVNVSVNQT 2498
Query: 400 LELHCESLRGSPPILYRFYHEDVTLGNSS-----APSGGGASFNLS-LTAEHSGNYSCDA 453
L C++ G P L + + V L S P G S + + A+ +G+Y C A
Sbjct: 2499 ALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLA 2554
Query: 454 DNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHE 513
N G+ G LRV P P + L CE+ P++ W+
Sbjct: 2555 SNSAGSDR-QGRDLRVLEP---PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2610
Query: 514 DDTLGNISAHSGGGASFNLSLTT----EHSGNYSCEADNGLGAQHSKV-VTLNVTGT-SR 567
+ + N L T + S + C N +G H VT++V T +
Sbjct: 2611 QKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2670
Query: 568 NRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSH-SPSECQEPSSSR 626
++T T + +VL+ A + +++A + L A G+ SPS E +
Sbjct: 2671 DQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ---LGARGSGYRVSPSGALEIGQAL 2727
Query: 627 P 627
P
Sbjct: 2728 P 2728
Score = 68.6 bits (166), Expect = 2e-11
Identities = 84/323 (26%), Positives = 128/323 (39%), Gaps = 24/323 (7%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRS-QIRVQRVPVSNVNLEIRPTGGQLIEGE 303
L+I D G Y C V S + R Q+RV P + E TG + +
Sbjct: 274 LRITGSHVGDEGRYQC----VAFSPAGQQARDFQLRVHAPPTIWGSNE---TGEVAVMED 326
Query: 304 NMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLA-ELHVLTVKESDAGRYYCAADN 362
++V + A+G T +W K+G + K + +L + + SDAG Y C A N
Sbjct: 327 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 386
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDV 422
R+ V +P + R V G + L C + RG P ++HE +
Sbjct: 387 AVGAAEKA-TRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGL 444
Query: 423 TLG--NSSAPSGGGASFNLSLTAE-HSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLT 479
+ N S G+ L E SG YSC A + G L+ +V V P
Sbjct: 445 PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE-----AVLQYSVEVQVPPQL 499
Query: 480 LRAPG---AQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSL 534
L A G +VG LEL C++ P + W + + L + S G +
Sbjct: 500 LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHV 559
Query: 535 TTEHSGNYSCEADNGLGAQHSKV 557
+HSG ++C+A N G ++V
Sbjct: 560 ELDHSGLFACQATNEAGTAGAEV 582
Score = 65.9 bits (159), Expect = 1e-10
Identities = 128/506 (25%), Positives = 192/506 (37%), Gaps = 54/506 (10%)
Query: 75 TEPGNYQC---KTRGSSLSDAVHVEFSPDWLILQALH-PVFEGDNVILRCQGKDNKNTHQ 130
++ G Y C G D V P ++ + L+ V ++V L CQ
Sbjct: 852 SDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVL 911
Query: 131 KVYYKDGKQL---PNSYNLEKITVNSVSR----DNSKYHCTAYRKFYILDIEVTSKPLNI 183
++KDG+ L P + + V R D Y C A + + K N+
Sbjct: 912 S-WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-----AGRSEKHYNL 965
Query: 184 QVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL---GLGWS 240
V + P+ + + T EG P +L+CE + P + S +D Q L G G
Sbjct: 966 NVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFP-----KISWRKDGQPLPGEGAGLQ 1020
Query: 241 RSPR----LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
L + G+Y CE V + S Q+ V VP PT
Sbjct: 1021 HVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVH-VPPQIAGPREPPTQ 1076
Query: 297 GQLIEGENMVLICSVAQGSGTVTFSWHKEGRV--RSLGRKTQRSLLAELHVLTVKESDAG 354
+++ L C+ A G T +W ++G+ LG + Q + LHV + + G
Sbjct: 1077 VSVVQDGVATLECN-ATGKPPPTVTWERDGQPVGAELGLQLQNQGQS-LHVERAQAAHTG 1134
Query: 355 RYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDL---LELHCESLRGSP 411
RY C A+N+ + ++V +P P L + L L L CE++ G P
Sbjct: 1135 RYSCVAENL-AGRAERKFELSVLVP---PELIGDLDPLTNITAALHSPLTLLCEAM-GIP 1189
Query: 412 PILYRFY--HEDVTLGNSSAPSGGGASFNLSLTAEH-SGNYSCDADNGLGAQHSHGVSLR 468
P R++ E V+ G + GG ++ T E SG YSC A N G + S+
Sbjct: 1190 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG-EARRNFSVE 1248
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAH--SGG 526
V VP S L + + G L C P L WF + L AH S
Sbjct: 1249 VLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWF-KDGRPLARGDAHHISPD 1306
Query: 527 GASFN-LSLTTEHSGNYSCEADNGLG 551
G L +G+YSC A N +G
Sbjct: 1307 GVLLQVLQANLSSAGHYSCIAANAVG 1332
Score = 64.3 bits (155), Expect = 4e-10
Identities = 92/321 (28%), Positives = 131/321 (40%), Gaps = 25/321 (7%)
Query: 244 RLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGE 303
+L+I ED+G+Y C + S ++ ++ VQ PV L T EG
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPVIENGLPDLST----TEGS 2862
Query: 304 NMVLICSVAQGSGTVTFSWHKEGR-VRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADN 362
+ L C A+GS +W K+G+ V K EL V ++ DAG Y C A+N
Sbjct: 2863 HAFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 2921
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPP--ILYRFYHE 420
+ RV + I V PV T +GD L L C + RGSP I +
Sbjct: 2922 A---VGRARRRVHLTILVL-PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDR 2976
Query: 421 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSR-PVLT 479
VT G S GG +++ E SG Y C A+N +G + VS V V PVL
Sbjct: 2977 PVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSF---VHVKEAPVLQ 3030
Query: 480 LRAPGAQAV-VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTT-E 537
A VG ++L C P ++W G+ H S + T +
Sbjct: 3031 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 3090
Query: 538 HSGNYSCEADNGLGAQHSKVV 558
+G Y C A+N +G V+
Sbjct: 3091 DAGRYQCLAENEMGVAKKVVI 3111
Score = 62.4 bits (150), Expect = 1e-09
Identities = 90/348 (25%), Positives = 138/348 (39%), Gaps = 33/348 (9%)
Query: 227 SLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVS 286
SL+ + + + +S P LQI + D G Y C + KR + ++ V
Sbjct: 641 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE-SKREVALKVLVPP---- 695
Query: 287 NVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE-LHV 345
N+E P ++E ++ L C +A G SW K + S S+ L +
Sbjct: 696 --NIEPGPVNKAVLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 752
Query: 346 LTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCE 405
+ SDAG Y C A NV ST +R +R+ V + + +V + L C
Sbjct: 753 EQAQLSDAGSYRCVASNVAG---STELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 809
Query: 406 SLRGSPPILYRFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCDADNG 456
+ P L + +D GN +P+G GG L S A SG YSC A +
Sbjct: 810 ATGAPSPTL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 864
Query: 457 LGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDT 516
+G + V L+V +P P + V + + L C+S P+L W+
Sbjct: 865 VG-EDRQDVVLQVHMP---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPL 920
Query: 517 LGNISAH-SGGGASFNLS-LTTEHSGNYSCEADNGLGAQHSKVVTLNV 562
H S A + +G+Y+CEA N G + K LNV
Sbjct: 921 EPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAG-RSEKHYNLNV 967
Score = 59.7 bits (143), Expect = 9e-09
Identities = 131/588 (22%), Positives = 218/588 (37%), Gaps = 83/588 (14%)
Query: 55 DTYWYHDEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLI--------LQA 106
DTY +LK+ + Q + G Y C S+ + FS + L+ L+
Sbjct: 1207 DTYLLAGGWMLKMTQTQEQ--DSGLYSCLA--SNEAGEARRNFSVEVLVPPSIENEDLEE 1262
Query: 107 LHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQL---------PNSYNLEKITVNSVSRD 157
+ V +G L C + + ++KDG+ L P+ L+ + N S
Sbjct: 1263 VIKVLDGQTAHLMCNVTGHPQP-KLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 1321
Query: 158 NSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIE------GSPMTLTC 211
+ Y C A V K + Q+ L +L + + E +P++L C
Sbjct: 1322 H--YSCIAANA-------VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLIC 1372
Query: 212 ETQLSPQRPDVQLQ-----FSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVT 266
E P P++ F R+ Q L + LQI ED+G Y C VT
Sbjct: 1373 EALAFPS-PNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTC---VVT 1424
Query: 267 HSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE---GENMVLICSVAQGSGTVTFSWH 323
+ + + + V P + + + G + ++ + L C + T W+
Sbjct: 1425 NELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY 1483
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVKE---SDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
K+G+ + + Q +L E +L ++ SD+GRY C A NV + + P+
Sbjct: 1484 KDGQPVTPSSRLQ--VLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPM 1541
Query: 381 SHPVLTFRA-----PRAHTVVGDLLE-----------LHCESLRGSPPILYRFYHED--V 422
V F A R G + E L+C++ PP L +Y ED +
Sbjct: 1542 FQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPL 1600
Query: 423 TLGNSSAPSGGGASFNLSLT-AEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLR 481
+ G+ + GG + L AE++G YSC A N +G H L +T PV
Sbjct: 1601 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL 1660
Query: 482 APGAQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSLTTEHS 539
+ L C +L P + W + + G + +
Sbjct: 1661 VEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADA 1720
Query: 540 GNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVL 587
+Y C A+N G+ K+ TL V R GL +T ++ S + L
Sbjct: 1721 ASYMCVAENQAGSA-EKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSL 1766
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/335 (23%), Positives = 133/335 (39%), Gaps = 51/335 (15%)
Query: 157 DNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLH----PVLRASSSTP----IEGSPMT 208
D +Y C A+ P Q ++ L P + S+ T +E +
Sbjct: 283 DEGRYQCVAF------------SPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQ 330
Query: 209 LTCETQLSPQRPDVQLQFSLFRDSQTLGLG----WSRSPR-LQIPAMWTEDSGSYWCEVE 263
L CE + P P++ + F+D L ++R R LQ+ + D+G Y C+
Sbjct: 331 LLCEARGVPT-PNI----TWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS 385
Query: 264 TVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWH 323
+ +K + VP + RP + + G + L C VA+G + T SWH
Sbjct: 386 NAVGAAEKATRLDVY----VPPTIEGAGGRPYVVKAVAGRPVALEC-VARGHPSPTLSWH 440
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVK---ESDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
EG + + L + VL ++ E+ +G Y C A SP ++ +V + V
Sbjct: 441 HEG--LPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS---SPAGEAVLQYSVEVQV 495
Query: 381 SHPVLTFRA-PRAHTVVGDLLELHCESLRGSPPILYRFYHED---VTLGNSSAPSGGGAS 436
+L + T+VG LEL C++ GSP ++ L S G
Sbjct: 496 PPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPTIQWLQNGRPAEELAGVQVASQGTTL 554
Query: 437 FNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ +HSG ++C A N G + G + V+V
Sbjct: 555 HIDHVELDHSGLFACQATNEAG---TAGAEVEVSV 586
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/375 (23%), Positives = 143/375 (38%), Gaps = 38/375 (10%)
Query: 197 SSSTPIEGSPMTLTCETQLSPQ------RPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAM 250
S+ T +P L CE SP+ + +L F L + + L S L + A
Sbjct: 2580 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL----LPSNALLLTAP 2635
Query: 251 WTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICS 310
+DS + C V++ + + Q+ V P + T + +VL C
Sbjct: 2636 GPQDSAQFEC---VVSNEVGEAHRLYQVTVHVPPT----IADDQTDFTVTMMAPVVLTCH 2688
Query: 311 VAQGSGTVTFSWHKEG-RVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILS 369
+ G T SW K G ++ + G + S L + AGRY C+A N + +
Sbjct: 2689 -STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN-SAGVAH 2746
Query: 370 TWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLR-GSPPILYRFYHEDVTLGNSS 428
+ +TV+ + PV+ V + + L CE+ P I ++ +V G S+
Sbjct: 2747 KHVFLTVQ---ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST 2803
Query: 429 APSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAV 488
GG + E +GNY C A N G+ L V VP PV+ P
Sbjct: 2804 QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTT 2859
Query: 489 VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSG------GGASFNLSLTTEHSGNY 542
G L C++ P + W D +S G G +L + +G Y
Sbjct: 2860 EGSHAFLPCKARGSPEPNITW----DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 2915
Query: 543 SCEADNGLGAQHSKV 557
+C A+N +G +V
Sbjct: 2916 TCTAENAVGRARRRV 2930
Score = 46.6 bits (109), Expect = 8e-05
Identities = 86/333 (25%), Positives = 124/333 (37%), Gaps = 49/333 (14%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
LQ+ A+ T DSG Y C T ++ S+ ++ + VP + P + +
Sbjct: 2446 LQLQALSTADSGDYSC---TARNAAGSTSVAFRVEIHTVPT----IRSGPPAVNVSVNQT 2498
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE--LHVLTVKESDAGRYYCAADN 362
+L C A G SW K+ RV R + +L E L + V DAG Y C A N
Sbjct: 2499 ALLPCQ-ADGVPAPLVSWRKD-RVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2556
Query: 363 -VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE- 420
S +RV + P P + AHT L CE+ GSP L ++ +
Sbjct: 2557 SAGSDRQGRDLRV-LEPPAIAPSPSNLTLTAHTPA----LLPCEA-SGSPKPLVVWWKDG 2610
Query: 421 ---DVTLGNSS---APSGGGASFNLSLTA---EHSGNYSCDADNGLGAQHSHGVSLRVTV 471
D L + PS L LTA + S + C N +G H +VTV
Sbjct: 2611 QKLDFRLQQGAYRLLPSNA-----LLLTAPGPQDSAQFECVVSNEVGEAHR---LYQVTV 2662
Query: 472 PVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFN 531
V + + ++ ++ L C S P + W G G G +
Sbjct: 2663 HVPPTIADDQTDFTVTMMAPVV-LTCHSTGIPAPTVSW-----SKAGAQLGARGSGYRVS 2716
Query: 532 LSLTTE-------HSGNYSCEADNGLGAQHSKV 557
S E H+G Y+C A N G H V
Sbjct: 2717 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHV 2749
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/248 (22%), Positives = 93/248 (37%), Gaps = 32/248 (12%)
Query: 230 RDSQTLGLGWSRSPR--------------LQIPAMWTEDSGSYWCEVETVTHSIKKRSLR 275
R S T +GW+ + R LQ A+ EDSG+Y C E + + +
Sbjct: 2962 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAE---NRVGRTQAV 3018
Query: 276 SQIRVQRVPVSN---VNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
S + V+ PV + + P GG + L C V +G W K+G
Sbjct: 3019 SFVHVKEAPVLQGEAFSYLVEPVGGSI------QLDC-VVRGDPVPDIHWIKDGLPLRGS 3071
Query: 333 RKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRA 392
+ L + + DAGRY C A+N + +V + + S PV
Sbjct: 3072 HLRHQLQNGSLTIHRTERDDAGRYQCLAENE----MGVAKKVVILVLQSAPVFQVEPQDM 3127
Query: 393 HTVVGDLLELHCESL-RGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC 451
GD + L C++ +P I + + + G+ + ++ +G Y C
Sbjct: 3128 TVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC 3187
Query: 452 DADNGLGA 459
A N LG+
Sbjct: 3188 VAHNLLGS 3195
Score = 38.5 bits (88), Expect = 0.023
Identities = 85/354 (24%), Positives = 129/354 (36%), Gaps = 46/354 (12%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
L + + DSG Y C V S + + +P S + E+ + ++ E+
Sbjct: 844 LTLASARASDSGRYSC----VAVSAVGEDRQDVVLQVHMPPSILGEELNVS---VVANES 896
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESD---AGRYYCAAD 361
+ L C + SW K+GR L + L A+ +L V +D AG Y C A
Sbjct: 897 VALECQ-SHAMPPPVLSWWKDGR--PLEPRPGVHLSADKALLQVDRADVWDAGHYTCEAL 953
Query: 362 NVHSPI-----LSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYR 416
N L+ W+ + SH LT R G L CE RG P
Sbjct: 954 NQAGRSEKHYNLNVWVAPVFPLRESH-TLTVRE-------GHPTSLSCEC-RGVPFPKIS 1004
Query: 417 FYHEDVTLGNSSA-----PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ + L A + G + G Y+C+ N +G S + L V V
Sbjct: 1005 WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHV 1063
Query: 472 PVSRPVLTLRAPGAQ-AVVGD-LLELHCESLRGSFPILYWFYHEDDTLG---NISAHSGG 526
P + R P Q +VV D + L C + P + W + +G + + G
Sbjct: 1064 PPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW-ERDGQPVGAELGLQLQNQG 1120
Query: 527 GASFNLSLTTEHSGNYSCEADNGLGAQHSK-----VVTLNVTGTSRNRTGLTAA 575
+ H+G YSC A+N G K +V + G T +TAA
Sbjct: 1121 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAA 1174
Score = 36.2 bits (82), Expect = 0.11
Identities = 100/396 (25%), Positives = 152/396 (38%), Gaps = 63/396 (15%)
Query: 205 SPMTLTCETQLSPQRPDVQLQFSLFRDSQTLG-------LGWSRSPRLQIPAMWTEDSGS 257
S +TL CE+ P P ++ ++D Q + LG R LQI DSG
Sbjct: 1464 STLTLECESWAVPP-PTIRW----YKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGR 1516
Query: 258 YWCEVETVTHSIKKRSLRSQIRV----QRVPVSNVNLEI-----RPTGG-----QLIEGE 303
Y C V T + I+V Q+V + EI GG +++E
Sbjct: 1517 YLC-VATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1575
Query: 304 NMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLT---VKESDAGRYYCAA 360
L C +W++E + S G + S+L VL V+ +AGRY C A
Sbjct: 1576 PAYLYCDT-NAIPPPDLTWYREDQPLSAGDEV--SVLQGGRVLQIPLVRAENAGRYSCKA 1632
Query: 361 DNVHSPILSTWIRVTVRIPVSHPVL---TFRAPRAHTV-VGDLLELHCESLRGSPPILYR 416
N + W+ + + ++ PV+ T TV + L C +L P +
Sbjct: 1633 SN---EVGEDWLHYELLV-LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1688
Query: 417 FYHEDVTLGNSSAPSG------GGASFNLSLTAE--HSGNYSCDADNGLGAQHSHGVSLR 468
+ G +PS G +S TAE + +Y C A+N G+ +LR
Sbjct: 1689 LQN-----GLPFSPSPRLQVLEDGQVLQVS-TAEVADAASYMCVAENQAGSAEKL-FTLR 1741
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDD-TLGNISAHSGGG 527
V VP L L A++ + L C+ P + W+ +LG G
Sbjct: 1742 VQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGT 1799
Query: 528 ASFNLSLTT-EHSGNYSCEADNGLGAQHSKVVTLNV 562
+ L SG Y+CEA N G + K+V L+V
Sbjct: 1800 HTLQLGRARLSDSGMYTCEALNAAG-RDQKLVQLSV 1834
Score = 32.0 bits (71), Expect = 2.1
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
Query: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQA----VV 489
G+ F S++ SG+Y C A N +G+ S L V VP S +R G +A +
Sbjct: 57 GSLFLASVSPADSGDYECQATNEVGST-SRRAKLVVYVPPS-----IREDGRKANVSGMA 110
Query: 490 GDLLELHCESLRGSFPILYW 509
G L L C++ P + W
Sbjct: 111 GQSLTLECDANGFPVPEIVW 130
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 87.8 bits (216), Expect = 3e-17
Identities = 140/564 (24%), Positives = 225/564 (39%), Gaps = 76/564 (13%)
Query: 33 TAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHD-------------KIQITEPGN 79
TA V+L C +H + WY D + L + + + ++++ G
Sbjct: 2948 TAILNSSVSLPCDVHAHP--NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM 3005
Query: 80 YQCKTRGSSLSDAVHVEFSPDWLILQALHP----------VFEGDNVILRCQGKDNKNTH 129
Y C+ ++ D V+ S L+ A V GD +L C+ D
Sbjct: 3006 YTCEALNAAGRDQKLVQLSV--LVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TDALPEP 3062
Query: 130 QKVYYKDGKQLPNSYNLE--------KITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPL 181
+YKDG+ L + + +I VS D Y C + V + L
Sbjct: 3063 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-DKGLYSCKVSN---VAGEAVRTFTL 3118
Query: 182 NIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSR 241
+QV F +P + + + + GSP+ LTC+ P L+ + +S + SR
Sbjct: 3119 TVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR 3176
Query: 242 SPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE 301
RLQ+ + +G+Y C E +K + + + R+ S V E ++E
Sbjct: 3177 GGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVARE-----HHVLE 3231
Query: 302 GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLL-----AELHVLTVKESDAGRY 356
G+ + L C A G +W K+G LG+ L L + ++ SDAG Y
Sbjct: 3232 GQEVRLDCE-ADGQPPPDVAWLKDG--SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 3288
Query: 357 YCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVV---GDLLELHCESLRGSPPI 413
C A H+P TV + V P + A + T+V G+L+ + C +RGSPPI
Sbjct: 3289 TCVA---HNPAGEDARLHTVNVLVP-PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPI 3343
Query: 414 LYRFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCDADNGLGAQHSHGVSLRVT 470
+ + + L S G G + +S + +G ++C A + G +L+V
Sbjct: 3344 HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVA-DRNFTLQVQ 3402
Query: 471 VPVSRPVLTLRAPGAQAVV--GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
VP PVL VV G L+EL CE+ P++ W + L S G
Sbjct: 3403 VP---PVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLL---SQSLEQGP 3456
Query: 529 SFNL-SLTTEHSGNYSCEADNGLG 551
S L ++ SG YSC A + G
Sbjct: 3457 SLQLEAVGAGDSGTYSCVAVSEAG 3480
Score = 82.4 bits (202), Expect = 1e-15
Identities = 90/357 (25%), Positives = 138/357 (38%), Gaps = 34/357 (9%)
Query: 205 SPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVET 264
+P+ LTC + P + ++ G S S L+I +G Y C
Sbjct: 3872 APVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN 3931
Query: 265 VTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHK 324
K + VQ PV ++ P+ + + E ++L C A G T +W K
Sbjct: 3932 SAGVAHKHVF---LTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPTITWQK 3983
Query: 325 EGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
EG + G TQ +L + DAG Y C A N + R+ V++P PV
Sbjct: 3984 EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PV 4039
Query: 385 LTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAP-SGGGASFNL---- 439
+ P T G L C++ RGSP ++T P SG F +
Sbjct: 4040 IENGLPDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSG 4091
Query: 440 -----SLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLE 494
+L + +G Y+C A+N +G V L + V PV T +GD L
Sbjct: 4092 ELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILV---LPVFTTLPGDRSLRLGDRLW 4147
Query: 495 LHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNGLG 551
L C + P + W ++ +S GG +++ E SG Y C A+N +G
Sbjct: 4148 LRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Score = 70.1 bits (170), Expect = 7e-12
Identities = 147/601 (24%), Positives = 241/601 (40%), Gaps = 90/601 (14%)
Query: 67 IKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPV-FEGDNVILR------ 119
++ K+Q+ + G + C +S + F+ + L PV F+ D V++R
Sbjct: 3369 LRISKVQLADAGIFTCVA--ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 3426
Query: 120 -CQGKDNKNTHQKVYYKDGKQLPNSYNLEK---ITVNSVSR-DNSKYHCTAY-------R 167
C+ + + KDG+ L S +LE+ + + +V D+ Y C A R
Sbjct: 3427 PCEAR-GVPLPLVSWMKDGEPLL-SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARR 3484
Query: 168 KFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFS 227
F + +E + Q EL L P G+PM L C+ Q +PQ P++ +
Sbjct: 3485 HFQLTVMEPPHIEDSGQPTELSLTP-----------GAPMELLCDAQGTPQ-PNI----T 3528
Query: 228 LFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSN 287
+D Q L + S ++ + D+G Y C E+ +I+K ++RVQ P N
Sbjct: 3529 WHKDGQALTRLENNSRATRV--LRVRDAGLYTCLAESPAGAIEK---SFRVRVQAPP--N 3581
Query: 288 VNLEIRPTGGQLIEG---ENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQ---RSLLA 341
+ + P G + + G +VL CSV + +WH++G V TQ R
Sbjct: 3582 I---VGPRGPRFVVGLAPGQLVLECSV-EAEPAPKITWHRDGIVLQEDAHTQFPERGRFL 3637
Query: 342 ELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRA--PRAHTVVGDL 399
+L L+ +D+G Y C A N ST + V I H V T R+ P + V
Sbjct: 3638 QLQALST--ADSGDYSCTARNAAG---STSVAFRVEI---HTVPTIRSGPPAVNVSVNQT 3689
Query: 400 LELHCESLRGSPPILYRFYHEDVTLGNSS-----APSGGGASFNLS-LTAEHSGNYSCDA 453
L C++ G P L + + V L S P G S + + A+ +G+Y C A
Sbjct: 3690 ALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLA 3745
Query: 454 DNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHE 513
N G+ G LRV P P + L CE+ P++ W+
Sbjct: 3746 SNSAGSDR-QGRDLRVLEP---PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 3801
Query: 514 DDTLGNISAHSGGGASFNLSLTT----EHSGNYSCEADNGLGAQHSKV-VTLNVTGT-SR 567
+ + N L T + S + C N +G H VT++V T +
Sbjct: 3802 QKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 3861
Query: 568 NRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSH-SPSECQEPSSSR 626
++T T + +VL+ A + +++A + L A G+ SPS E +
Sbjct: 3862 DQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ---LGARGSGYRVSPSGALEIGQAL 3918
Query: 627 P 627
P
Sbjct: 3919 P 3919
Score = 68.6 bits (166), Expect = 2e-11
Identities = 84/323 (26%), Positives = 128/323 (39%), Gaps = 24/323 (7%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRS-QIRVQRVPVSNVNLEIRPTGGQLIEGE 303
L+I D G Y C V S + R Q+RV P + E TG + +
Sbjct: 1465 LRITGSHVGDEGRYQC----VAFSPAGQQARDFQLRVHAPPTIWGSNE---TGEVAVMED 1517
Query: 304 NMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLA-ELHVLTVKESDAGRYYCAADN 362
++V + A+G T +W K+G + K + +L + + SDAG Y C A N
Sbjct: 1518 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 1577
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDV 422
R+ V +P + R V G + L C + RG P ++HE +
Sbjct: 1578 AVGAAEKA-TRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGL 1635
Query: 423 TLG--NSSAPSGGGASFNLSLTAE-HSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLT 479
+ N S G+ L E SG YSC A + G L+ +V V P
Sbjct: 1636 PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE-----AVLQYSVEVQVPPQL 1690
Query: 480 LRAPG---AQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSL 534
L A G +VG LEL C++ P + W + + L + S G +
Sbjct: 1691 LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHV 1750
Query: 535 TTEHSGNYSCEADNGLGAQHSKV 557
+HSG ++C+A N G ++V
Sbjct: 1751 ELDHSGLFACQATNEAGTAGAEV 1773
Score = 68.2 bits (165), Expect = 3e-11
Identities = 104/376 (27%), Positives = 150/376 (39%), Gaps = 70/376 (18%)
Query: 242 SPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE 301
S L++ + DSG Y C T ++ S R + VQ P ++ P +++
Sbjct: 1081 SGSLRLAQVQVGDSGHYEC---TASNPAGSASHRYVLGVQVPP----QVQPGPRVLKVLV 1133
Query: 302 GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAAD 361
GE + L C VA+G+ SW K+G V GR Q S+ H ++ SDAGRY C A
Sbjct: 1134 GEALDLNC-VAEGNPEPQLSWSKDGVVLQ-GRGPQGSV----HFAAIRTSDAGRYRCEAS 1187
Query: 362 NVHSPILSTWIRVTVRI-PVSHPVLTFRAPRAHTVVGDLLELHCESLRGS--PPILYRFY 418
N S + W V +R+ H + V G+ L C + RG+ P + +R
Sbjct: 1188 N--SAGVDAW-EVELRVLEPPHWGADETSGLLERVAGENASLPCPA-RGTPKPQVTWR-- 1241
Query: 419 HEDVTLGNSSAPSGG---------GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRV 469
G SS P G G+ F S++ SG+Y C A N +G+ S L V
Sbjct: 1242 -----KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGST-SRRAKLVV 1295
Query: 470 TVPVSRPVLTLRAPGAQA----VVGDLLELHCESLRGSFPILYWF--------------Y 511
VP S +R G +A + G L L C++ P + W Y
Sbjct: 1296 YVPPS-----IREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGY 1350
Query: 512 HEDDTLGNISAHS--GGGASFNLSLTTE-HSGNYSCEADNGLGAQHSKVVTLNVT----- 563
D G + H G S + E SG YSC A+N G L +T
Sbjct: 1351 GWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVL 1410
Query: 564 --GTSRNRTGLTAAGI 577
G ++ GL A +
Sbjct: 1411 GAGAAQEVLGLAGADV 1426
Score = 67.0 bits (162), Expect = 6e-11
Identities = 136/593 (22%), Positives = 217/593 (36%), Gaps = 79/593 (13%)
Query: 8 LILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISH-----SLAQGDTYWYHDE 62
L+ G SGVAP A L+ P + + + + CS S L +G+ +
Sbjct: 412 LLRVSGVSYSGVAPGAPLVSMAPRIHGYLHQPLLVSCSVHSALPFRLQLRRGEARLGEER 471
Query: 63 KLLKIKHDKIQI-----TEPGNYQCKT---RGSSLSDAVHVEFSPDWLILQALH-PVFEG 113
+ + +I E G Y+C G+ + A V P ++ A + V G
Sbjct: 472 HFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPG 531
Query: 114 DNVILRCQGKDNKNTHQKVYYKDGKQLPNSY-------NLEKITVNSVSRDNSKYHCTAY 166
+ +L C+ + + + +D + LP S +L + D +Y C A
Sbjct: 532 ETAVLSCRVL-GEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVAS 590
Query: 167 RKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQF 226
+ V L + ++ +H SS +G + ++C P
Sbjct: 591 NANGVTRASVWL--LVREAPQVSIH----TSSQHFSQGVEVKVSCSASGYPTP-----HI 639
Query: 227 SLFRDSQTLGLGWSRSPRLQIPAMWT--------EDSGSYWCEVETVTHSIKKRSLRSQI 278
S R+SQ L R+ + A T ED+G+Y C+ T+ + +
Sbjct: 640 SWSRESQAL----QEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA---TNEVGTDQETVTL 692
Query: 279 RVQRVP-VSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQR 337
P VS VN + + GE VL+C A G W++ G L +
Sbjct: 693 YYTDPPSVSAVNAVVL-----VAVGEEAVLVCE-ASGVPPPRVIWYRGGLEMILAPEGSS 746
Query: 338 SLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTV-V 396
S +L + +E DAG Y C A N + +++ V H PR TV +
Sbjct: 747 S--GKLRIPAAQERDAGTYTCRAVNELGDASAE-----IQLAVGHAPQLTELPRDVTVEL 799
Query: 397 GDLLELHCESLRGSPPILYRFYHEDVTLG--------NSSAPSGGGASFNLSLTAEHSGN 448
G L C + PP + + LG + S G F S+ E
Sbjct: 800 GRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAP 859
Query: 449 YSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGS-FPIL 507
Y C+A N G + + + + P + AP + + G + L C L G P
Sbjct: 860 YVCEARNVFGKVQAE--ARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPER 917
Query: 508 YWFYHEDDTLGNISAHS---GGGASFNLSLTTEHSGNYSCEADNGLGAQHSKV 557
+W + L S HS G + +L EH+G YSC A N G+QH V
Sbjct: 918 HWL-KDGRPLPPGSRHSIRADGSLHLDRALQ-EHAGRYSCVATNTAGSQHRDV 968
Score = 65.9 bits (159), Expect = 1e-10
Identities = 128/506 (25%), Positives = 192/506 (37%), Gaps = 54/506 (10%)
Query: 75 TEPGNYQC---KTRGSSLSDAVHVEFSPDWLILQALH-PVFEGDNVILRCQGKDNKNTHQ 130
++ G Y C G D V P ++ + L+ V ++V L CQ
Sbjct: 2043 SDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVL 2102
Query: 131 KVYYKDGKQL---PNSYNLEKITVNSVSR----DNSKYHCTAYRKFYILDIEVTSKPLNI 183
++KDG+ L P + + V R D Y C A + + K N+
Sbjct: 2103 S-WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-----AGHSEKHYNL 2156
Query: 184 QVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL---GLGWS 240
V + P+ + + T EG P +L+CE + P + S +D Q L G G
Sbjct: 2157 NVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFP-----KISWRKDGQPLPGEGAGLQ 2211
Query: 241 RSPR----LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
L + G+Y CE V + S Q+ V VP PT
Sbjct: 2212 HVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVH-VPPQIAGPREPPTQ 2267
Query: 297 GQLIEGENMVLICSVAQGSGTVTFSWHKEGRV--RSLGRKTQRSLLAELHVLTVKESDAG 354
+++ L C+ A G T +W ++G+ LG + Q + LHV + + G
Sbjct: 2268 VSVVQDGVATLECN-ATGKPPPTVTWERDGQPVGAELGLQLQNQGQS-LHVERAQAAHTG 2325
Query: 355 RYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDL---LELHCESLRGSP 411
RY C A+N+ + ++V +P P L + L L L CE++ G P
Sbjct: 2326 RYSCVAENL-AGRAERKFELSVLVP---PELIGDLDPLTNITAALHSPLTLLCEAM-GIP 2380
Query: 412 PILYRFY--HEDVTLGNSSAPSGGGASFNLSLTAEH-SGNYSCDADNGLGAQHSHGVSLR 468
P R++ E V+ G + GG ++ T E SG YSC A N G + S+
Sbjct: 2381 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG-EARRNFSVE 2439
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAH--SGG 526
V VP S L + + G L C P L WF + L AH S
Sbjct: 2440 VLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWF-KDGRPLARGDAHHISPD 2497
Query: 527 GASFN-LSLTTEHSGNYSCEADNGLG 551
G L +G+YSC A N +G
Sbjct: 2498 GVLLQVLQANLSSAGHYSCIAANAVG 2523
Score = 64.3 bits (155), Expect = 4e-10
Identities = 92/321 (28%), Positives = 131/321 (40%), Gaps = 25/321 (7%)
Query: 244 RLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGE 303
+L+I ED+G+Y C + S ++ ++ VQ PV L T EG
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPVIENGLPDLST----TEGS 4053
Query: 304 NMVLICSVAQGSGTVTFSWHKEGR-VRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADN 362
+ L C A+GS +W K+G+ V K EL V ++ DAG Y C A+N
Sbjct: 4054 HAFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 4112
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPP--ILYRFYHE 420
+ RV + I V PV T +GD L L C + RGSP I +
Sbjct: 4113 A---VGRARRRVHLTILVL-PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDR 4167
Query: 421 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSR-PVLT 479
VT G S GG +++ E SG Y C A+N +G + VS V V PVL
Sbjct: 4168 PVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSF---VHVKEAPVLQ 4221
Query: 480 LRAPGAQAV-VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTT-E 537
A VG ++L C P ++W G+ H S + T +
Sbjct: 4222 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERD 4281
Query: 538 HSGNYSCEADNGLGAQHSKVV 558
+G Y C A+N +G V+
Sbjct: 4282 DAGRYQCLAENEMGVAKKVVI 4302
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/348 (25%), Positives = 137/348 (39%), Gaps = 33/348 (9%)
Query: 227 SLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVS 286
SL+ + + + +S P LQI + D G Y C + KR + ++ V
Sbjct: 1832 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE-SKREVALKVLVPP---- 1886
Query: 287 NVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE-LHV 345
N+E P ++E ++ L C +A G SW K + S S+ L +
Sbjct: 1887 --NIEPGPVNKAVLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 1943
Query: 346 LTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCE 405
+ SDAG Y C A NV ST +R +R+ V + + +V + L C
Sbjct: 1944 EQAQLSDAGSYRCVASNVAG---STELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 2000
Query: 406 SLRGSPPILYRFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCDADNG 456
+ P L + +D GN +P+G GG L S A SG YSC A +
Sbjct: 2001 ATGAPSPTL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 2055
Query: 457 LGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDT 516
+G + V L+V +P P + V + + L C+S P+L W+
Sbjct: 2056 VG-EDRQDVVLQVHMP---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPL 2111
Query: 517 LGNISAH-SGGGASFNLS-LTTEHSGNYSCEADNGLGAQHSKVVTLNV 562
H S A + +G+Y+CEA N G K LNV
Sbjct: 2112 EPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAG-HSEKHYNLNV 2158
Score = 59.7 bits (143), Expect = 9e-09
Identities = 131/588 (22%), Positives = 218/588 (37%), Gaps = 83/588 (14%)
Query: 55 DTYWYHDEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLI--------LQA 106
DTY +LK+ + Q + G Y C S+ + FS + L+ L+
Sbjct: 2398 DTYLLAGGWMLKMTQTQEQ--DSGLYSCLA--SNEAGEARRNFSVEVLVPPSIENEDLEE 2453
Query: 107 LHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQL---------PNSYNLEKITVNSVSRD 157
+ V +G L C + + ++KDG+ L P+ L+ + N S
Sbjct: 2454 VIKVLDGQTAHLMCNVTGHPQP-KLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 2512
Query: 158 NSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIE------GSPMTLTC 211
+ Y C A V K + Q+ L +L + + E +P++L C
Sbjct: 2513 H--YSCIAANA-------VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLIC 2563
Query: 212 ETQLSPQRPDVQLQ-----FSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVT 266
E P P++ F R+ Q L + LQI ED+G Y C VT
Sbjct: 2564 EALAFPS-PNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTC---VVT 2615
Query: 267 HSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE---GENMVLICSVAQGSGTVTFSWH 323
+ + + + V P + + + G + ++ + L C + T W+
Sbjct: 2616 NELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY 2674
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVKE---SDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
K+G+ + + Q +L E +L ++ SD+GRY C A NV + + P+
Sbjct: 2675 KDGQPVTPSSRLQ--VLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPM 2732
Query: 381 SHPVLTFRA-----PRAHTVVGDLLE-----------LHCESLRGSPPILYRFYHED--V 422
V F A R G + E L+C++ PP L +Y ED +
Sbjct: 2733 FQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPL 2791
Query: 423 TLGNSSAPSGGGASFNLSLT-AEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLR 481
+ G+ + GG + L AE++G YSC A N +G H L +T PV
Sbjct: 2792 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL 2851
Query: 482 APGAQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSLTTEHS 539
+ L C +L P + W + + G + +
Sbjct: 2852 VEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADA 2911
Query: 540 GNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVL 587
+Y C A+N G+ K+ TL V R GL +T ++ S + L
Sbjct: 2912 ASYMCVAENQAGSA-EKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSL 2957
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/335 (23%), Positives = 133/335 (39%), Gaps = 51/335 (15%)
Query: 157 DNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLH----PVLRASSSTP----IEGSPMT 208
D +Y C A+ P Q ++ L P + S+ T +E +
Sbjct: 1474 DEGRYQCVAF------------SPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQ 1521
Query: 209 LTCETQLSPQRPDVQLQFSLFRDSQTLGLG----WSRSPR-LQIPAMWTEDSGSYWCEVE 263
L CE + P P++ + F+D L ++R R LQ+ + D+G Y C+
Sbjct: 1522 LLCEARGVPT-PNI----TWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS 1576
Query: 264 TVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWH 323
+ +K + VP + RP + + G + L C VA+G + T SWH
Sbjct: 1577 NAVGAAEKATRLDVY----VPPTIEGAGGRPYVVKAVAGRPVALEC-VARGHPSPTLSWH 1631
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVK---ESDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
EG + + L + VL ++ E+ +G Y C A SP ++ +V + V
Sbjct: 1632 HEG--LPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS---SPAGEAVLQYSVEVQV 1686
Query: 381 SHPVLTFRA-PRAHTVVGDLLELHCESLRGSPPILYRFYHED---VTLGNSSAPSGGGAS 436
+L + T+VG LEL C++ GSP ++ L S G
Sbjct: 1687 PPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPTIQWLQNGRPAEELAGVQVASQGTTL 1745
Query: 437 FNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ +HSG ++C A N G + G + V+V
Sbjct: 1746 HIDHVELDHSGLFACQATNEAG---TAGAEVEVSV 1777
Score = 48.9 bits (115), Expect = 2e-05
Identities = 126/529 (23%), Positives = 195/529 (36%), Gaps = 77/529 (14%)
Query: 72 IQITEPGNYQCKTRGSSLSDAVHVEF----SPDWLI--LQALHPVFEGDNVILRCQGKDN 125
I+ ++ G Y+C+ S+ DA VE P W L G+N L C +
Sbjct: 1174 IRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGT 1233
Query: 126 KNTHQKVYYKDGKQ------LPNSYNLEK--ITVNSVS-RDNSKYHCTAYRKFYILDIEV 176
+V ++ G P LE+ + + SVS D+ Y C A ++
Sbjct: 1234 PK--PQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATN-----EVGS 1286
Query: 177 TSKPLNIQVQELFLHPVL----RASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDS 232
TS+ + V ++ P + R ++ + + G +TL C+ P V L +D+
Sbjct: 1287 TSRRAKLVV---YVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWL-----KDA 1338
Query: 233 QTLG--LGWS------------------RSPRLQIPAMWTEDSGSYWCEVETVTHSIKKR 272
Q +G LGW+ L P + DSG Y C E + ++
Sbjct: 1339 QLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRD 1398
Query: 273 SLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
+ V + E+ G +E L C + G T W K+ R L
Sbjct: 1399 FHLLVLTPPSVLGAGAAQEVLGLAGADVE-----LQCWTS-GVPTPQVEWTKD-RQPVLP 1451
Query: 333 RKTQRSLLAELHVLTVKES---DAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRA 389
+ + VL + S D GRY C A SP +R+ +
Sbjct: 1452 GGPHLQVQEDGQVLRITGSHVGDEGRYQCVA---FSPAGQQARDFQLRVHAPPTIWGSNE 1508
Query: 390 PRAHTVVGD-LLELHCESLRGSPPILYRFYHEDVTLGNSS--APSGGGASFNLS-LTAEH 445
V+ D L++L CE+ RG P ++ + L S+ + GG L +
Sbjct: 1509 TGEVAVMEDHLVQLLCEA-RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSD 1567
Query: 446 SGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFP 505
+G Y+C A N +GA L V VP + R +AV G + L C + P
Sbjct: 1568 AGVYTCKASNAVGAAEK-ATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 1626
Query: 506 ILYWFYHEDDTL--GNISAHSGGGASFNLSLTTE-HSGNYSCEADNGLG 551
L W +HE + N S G+ L E SG YSC A + G
Sbjct: 1627 TLSW-HHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAG 1674
Score = 48.5 bits (114), Expect = 2e-05
Identities = 113/551 (20%), Positives = 185/551 (33%), Gaps = 105/551 (19%)
Query: 76 EPGNYQCKTRGSSLSDAVHVEF----SPDWLILQALHPVFEGDNVILRCQGKDNKNTHQK 131
+ GNY C+ +D V P + A+ V G+ +L C+ +
Sbjct: 671 DAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEAS-GVPPPRV 729
Query: 132 VYYKDGKQL---PNSYNLEKITVNSVS-RDNSKYHCTAYRKFYILDIEVTSKPLNIQVQE 187
++Y+ G ++ P + K+ + + RD Y C A E+ IQ+
Sbjct: 730 IWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVN-------ELGDASAEIQLAV 782
Query: 188 LFLHPVLRASSSTPIE-GSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGL--GWSRSPR 244
+ +E G L C P P V + D Q LGL G R R
Sbjct: 783 GHAPQLTELPRDVTVELGRSALLACRATGRPP-PTVTWRRG---DGQPLGLRLGAGRGSR 838
Query: 245 LQIP--------AMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
+ P ++ ED Y CE V + Q + + + +I +
Sbjct: 839 SRQPDSGVLFFESVAPEDQAPYVCEARNVFGKV-------QAEARLIVTGHAPPQIASSA 891
Query: 297 G--QLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAG 354
+++EG+ + L C V G W K+GR G + LH+ + AG
Sbjct: 892 PTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAG 951
Query: 355 RYYCAADNVHSPILSTWIRVTVRIPVS-HPVLTFRAPRAHTVVGDLLELHCESLRGSPPI 413
RY C A N + + + V++P HP T H + + + + P
Sbjct: 952 RYSCVATNT-AGSQHRDVELVVQVPPRIHPTAT------HHITNEGVPASLPCVASGVPA 1004
Query: 414 LYRFYHEDVTLGNSSAP----SGGGASFNLSLTAEHSGNYSCDADNGLG----------- 458
+ ++ S P S G +A+ +G Y C A N +G
Sbjct: 1005 PTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN 1064
Query: 459 ----------------------AQHSHGVSLRVTVPVSRP--------VLTLRAPG---- 484
AQ G S S P VL ++ P
Sbjct: 1065 RLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQP 1124
Query: 485 ----AQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSG 540
+ +VG+ L+L+C + P L W +D + + G+ ++ T +G
Sbjct: 1125 GPRVLKVLVGEALDLNCVAEGNPEPQLSW--SKDGVV--LQGRGPQGSVHFAAIRTSDAG 1180
Query: 541 NYSCEADNGLG 551
Y CEA N G
Sbjct: 1181 RYRCEASNSAG 1191
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/375 (23%), Positives = 143/375 (38%), Gaps = 38/375 (10%)
Query: 197 SSSTPIEGSPMTLTCETQLSPQ------RPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAM 250
S+ T +P L CE SP+ + +L F L + + L S L + A
Sbjct: 3771 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL----LPSNALLLTAP 3826
Query: 251 WTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICS 310
+DS + C V++ + + Q+ V P + T + +VL C
Sbjct: 3827 GPQDSAQFEC---VVSNEVGEAHRLYQVTVHVPPT----IADDQTDFTVTMMAPVVLTCH 3879
Query: 311 VAQGSGTVTFSWHKEG-RVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILS 369
+ G T SW K G ++ + G + S L + AGRY C+A N + +
Sbjct: 3880 -STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN-SAGVAH 3937
Query: 370 TWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLR-GSPPILYRFYHEDVTLGNSS 428
+ +TV+ + PV+ V + + L CE+ P I ++ +V G S+
Sbjct: 3938 KHVFLTVQ---ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST 3994
Query: 429 APSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAV 488
GG + E +GNY C A N G+ L V VP PV+ P
Sbjct: 3995 QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTT 4050
Query: 489 VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSG------GGASFNLSLTTEHSGNY 542
G L C++ P + W D +S G G +L + +G Y
Sbjct: 4051 EGSHAFLPCKARGSPEPNITW----DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 4106
Query: 543 SCEADNGLGAQHSKV 557
+C A+N +G +V
Sbjct: 4107 TCTAENAVGRARRRV 4121
Score = 46.6 bits (109), Expect = 8e-05
Identities = 86/333 (25%), Positives = 124/333 (37%), Gaps = 49/333 (14%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
LQ+ A+ T DSG Y C T ++ S+ ++ + VP + P + +
Sbjct: 3637 LQLQALSTADSGDYSC---TARNAAGSTSVAFRVEIHTVPT----IRSGPPAVNVSVNQT 3689
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE--LHVLTVKESDAGRYYCAADN 362
+L C A G SW K+ RV R + +L E L + V DAG Y C A N
Sbjct: 3690 ALLPCQ-ADGVPAPLVSWRKD-RVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 3747
Query: 363 -VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE- 420
S +RV + P P + AHT L CE+ GSP L ++ +
Sbjct: 3748 SAGSDRQGRDLRV-LEPPAIAPSPSNLTLTAHTPA----LLPCEA-SGSPKPLVVWWKDG 3801
Query: 421 ---DVTLGNSS---APSGGGASFNLSLTA---EHSGNYSCDADNGLGAQHSHGVSLRVTV 471
D L + PS L LTA + S + C N +G H +VTV
Sbjct: 3802 QKLDFRLQQGAYRLLPSNA-----LLLTAPGPQDSAQFECVVSNEVGEAHR---LYQVTV 3853
Query: 472 PVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFN 531
V + + ++ ++ L C S P + W G G G +
Sbjct: 3854 HVPPTIADDQTDFTVTMMAPVV-LTCHSTGIPAPTVSW-----SKAGAQLGARGSGYRVS 3907
Query: 532 LSLTTE-------HSGNYSCEADNGLGAQHSKV 557
S E H+G Y+C A N G H V
Sbjct: 3908 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHV 3940
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/248 (22%), Positives = 93/248 (37%), Gaps = 32/248 (12%)
Query: 230 RDSQTLGLGWSRSPR--------------LQIPAMWTEDSGSYWCEVETVTHSIKKRSLR 275
R S T +GW+ + R LQ A+ EDSG+Y C E + + +
Sbjct: 4153 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAE---NRVGRTQAV 4209
Query: 276 SQIRVQRVPVSN---VNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
S + V+ PV + + P GG + L C V +G W K+G
Sbjct: 4210 SFVHVKEAPVLQGEAFSYLVEPVGGSI------QLDC-VVRGDPVPDIHWIKDGLPLRGS 4262
Query: 333 RKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRA 392
+ L + + DAGRY C A+N + +V + + S PV
Sbjct: 4263 HLRHQLQNGSLTIHRTERDDAGRYQCLAENE----MGVAKKVVILVLQSAPVFQVEPQDM 4318
Query: 393 HTVVGDLLELHCESL-RGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC 451
GD + L C++ +P I + + + G+ + ++ +G Y C
Sbjct: 4319 TVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC 4378
Query: 452 DADNGLGA 459
A N LG+
Sbjct: 4379 VAHNLLGS 4386
Score = 39.7 bits (91), Expect = 0.010
Identities = 87/354 (24%), Positives = 131/354 (37%), Gaps = 46/354 (12%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
L + + DSG Y C V S + + +P S + E+ + ++ E+
Sbjct: 2035 LTLASARASDSGRYSC----VAVSAVGEDRQDVVLQVHMPPSILGEELNVS---VVANES 2087
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESD---AGRYYCAAD 361
+ L C + SW K+GR L + L A+ +L V +D AG Y C A
Sbjct: 2088 VALECQ-SHAMPPPVLSWWKDGR--PLEPRPGVHLSADKALLQVDRADVWDAGHYTCEAL 2144
Query: 362 NV--HSPI---LSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYR 416
N HS L+ W+ + SH LT R G L CE RG P
Sbjct: 2145 NQAGHSEKHYNLNVWVAPVFPLRESH-TLTVRE-------GHPTSLSCEC-RGVPFPKIS 2195
Query: 417 FYHEDVTLGNSSA-----PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ + L A + G + G Y+C+ N +G S + L V V
Sbjct: 2196 WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHV 2254
Query: 472 PVSRPVLTLRAPGAQ-AVVGD-LLELHCESLRGSFPILYWFYHEDDTLG---NISAHSGG 526
P + R P Q +VV D + L C + P + W + +G + + G
Sbjct: 2255 PPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW-ERDGQPVGAELGLQLQNQG 2311
Query: 527 GASFNLSLTTEHSGNYSCEADNGLGAQHSK-----VVTLNVTGTSRNRTGLTAA 575
+ H+G YSC A+N G K +V + G T +TAA
Sbjct: 2312 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAA 2365
Score = 36.2 bits (82), Expect = 0.11
Identities = 100/396 (25%), Positives = 152/396 (38%), Gaps = 63/396 (15%)
Query: 205 SPMTLTCETQLSPQRPDVQLQFSLFRDSQTLG-------LGWSRSPRLQIPAMWTEDSGS 257
S +TL CE+ P P ++ ++D Q + LG R LQI DSG
Sbjct: 2655 STLTLECESWAVPP-PTIRW----YKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGR 2707
Query: 258 YWCEVETVTHSIKKRSLRSQIRV----QRVPVSNVNLEI-----RPTGG-----QLIEGE 303
Y C V T + I+V Q+V + EI GG +++E
Sbjct: 2708 YLC-VATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766
Query: 304 NMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLT---VKESDAGRYYCAA 360
L C +W++E + S G + S+L VL V+ +AGRY C A
Sbjct: 2767 PAYLYCDT-NAIPPPDLTWYREDQPLSAGDEV--SVLQGGRVLQIPLVRAENAGRYSCKA 2823
Query: 361 DNVHSPILSTWIRVTVRIPVSHPVL---TFRAPRAHTV-VGDLLELHCESLRGSPPILYR 416
N + W+ + + ++ PV+ T TV + L C +L P +
Sbjct: 2824 SN---EVGEDWLHYELLV-LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 2879
Query: 417 FYHEDVTLGNSSAPSG------GGASFNLSLTAE--HSGNYSCDADNGLGAQHSHGVSLR 468
+ G +PS G +S TAE + +Y C A+N G+ +LR
Sbjct: 2880 LQN-----GLPFSPSPRLQVLEDGQVLQVS-TAEVADAASYMCVAENQAGSAEKL-FTLR 2932
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDD-TLGNISAHSGGG 527
V VP L L A++ + L C+ P + W+ +LG G
Sbjct: 2933 VQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGT 2990
Query: 528 ASFNLSLTT-EHSGNYSCEADNGLGAQHSKVVTLNV 562
+ L SG Y+CEA N G + K+V L+V
Sbjct: 2991 HTLQLGRARLSDSGMYTCEALNAAG-RDQKLVQLSV 3025
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 87.8 bits (216), Expect = 3e-17
Identities = 140/564 (24%), Positives = 225/564 (39%), Gaps = 76/564 (13%)
Query: 33 TAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHD-------------KIQITEPGN 79
TA V+L C +H + WY D + L + + + ++++ G
Sbjct: 1666 TAILNSSVSLPCDVHAHP--NPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGM 1723
Query: 80 YQCKTRGSSLSDAVHVEFSPDWLILQALHP----------VFEGDNVILRCQGKDNKNTH 129
Y C+ ++ D V+ S L+ A V GD +L C+ D
Sbjct: 1724 YTCEALNAAGRDQKLVQLSV--LVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TDALPEP 1780
Query: 130 QKVYYKDGKQLPNSYNLE--------KITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPL 181
+YKDG+ L + + +I VS D Y C + V + L
Sbjct: 1781 TVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-DKGLYSCKVSN---VAGEAVRTFTL 1836
Query: 182 NIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSR 241
+QV F +P + + + + GSP+ LTC+ P L+ + +S + SR
Sbjct: 1837 TVQVPPTFENP--KTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSR 1894
Query: 242 SPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE 301
RLQ+ + +G+Y C E +K + + + R+ S V E ++E
Sbjct: 1895 GGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVARE-----HHVLE 1949
Query: 302 GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLL-----AELHVLTVKESDAGRY 356
G+ + L C A G +W K+G LG+ L L + ++ SDAG Y
Sbjct: 1950 GQEVRLDCE-ADGQPPPDVAWLKDG--SPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2006
Query: 357 YCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVV---GDLLELHCESLRGSPPI 413
C A H+P TV + V P + A + T+V G+L+ + C +RGSPPI
Sbjct: 2007 TCVA---HNPAGEDARLHTVNVLVP-PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPI 2061
Query: 414 LYRFYHEDVTLGNSSAP--SGGGASFNLS-LTAEHSGNYSCDADNGLGAQHSHGVSLRVT 470
+ + + L S G G + +S + +G ++C A + G +L+V
Sbjct: 2062 HVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVA-DRNFTLQVQ 2120
Query: 471 VPVSRPVLTLRAPGAQAVV--GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
VP PVL VV G L+EL CE+ P++ W + L S G
Sbjct: 2121 VP---PVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLL---SQSLEQGP 2174
Query: 529 SFNL-SLTTEHSGNYSCEADNGLG 551
S L ++ SG YSC A + G
Sbjct: 2175 SLQLEAVGAGDSGTYSCVAVSEAG 2198
Score = 82.4 bits (202), Expect = 1e-15
Identities = 90/357 (25%), Positives = 138/357 (38%), Gaps = 34/357 (9%)
Query: 205 SPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVET 264
+P+ LTC + P + ++ G S S L+I +G Y C
Sbjct: 2590 APVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN 2649
Query: 265 VTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHK 324
K + VQ PV ++ P+ + + E ++L C A G T +W K
Sbjct: 2650 SAGVAHKHVF---LTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPTITWQK 2701
Query: 325 EGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPV 384
EG + G TQ +L + DAG Y C A N + R+ V++P PV
Sbjct: 2702 EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PV 2757
Query: 385 LTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAP-SGGGASFNL---- 439
+ P T G L C++ RGSP ++T P SG F +
Sbjct: 2758 IENGLPDLSTTEGSHAFLPCKA-RGSP-------EPNITWDKDGQPVSGAEGKFTIQPSG 2809
Query: 440 -----SLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLE 494
+L + +G Y+C A+N +G V L + V PV T +GD L
Sbjct: 2810 ELLVKNLEGQDAGTYTCTAENAVGRARRR-VHLTILV---LPVFTTLPGDRSLRLGDRLW 2865
Query: 495 LHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNGLG 551
L C + P + W ++ +S GG +++ E SG Y C A+N +G
Sbjct: 2866 LRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Score = 70.1 bits (170), Expect = 7e-12
Identities = 147/601 (24%), Positives = 241/601 (40%), Gaps = 90/601 (14%)
Query: 67 IKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPV-FEGDNVILR------ 119
++ K+Q+ + G + C +S + F+ + L PV F+ D V++R
Sbjct: 2087 LRISKVQLADAGIFTCVA--ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2144
Query: 120 -CQGKDNKNTHQKVYYKDGKQLPNSYNLEK---ITVNSVSR-DNSKYHCTAY-------R 167
C+ + + KDG+ L S +LE+ + + +V D+ Y C A R
Sbjct: 2145 PCEAR-GVPLPLVSWMKDGEPLL-SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARR 2202
Query: 168 KFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFS 227
F + +E + Q EL L P G+PM L C+ Q +PQ P++ +
Sbjct: 2203 HFQLTVMEPPHIEDSGQPTELSLTP-----------GAPMELLCDAQGTPQ-PNI----T 2246
Query: 228 LFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSN 287
+D Q L + S ++ + D+G Y C E+ +I+K ++RVQ P N
Sbjct: 2247 WHKDGQALTRLENNSRATRV--LRVRDAGLYTCLAESPAGAIEK---SFRVRVQAPP--N 2299
Query: 288 VNLEIRPTGGQLIEG---ENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQ---RSLLA 341
+ + P G + + G +VL CSV + +WH++G V TQ R
Sbjct: 2300 I---VGPRGPRFVVGLAPGQLVLECSV-EAEPAPKITWHRDGIVLQEDAHTQFPERGRFL 2355
Query: 342 ELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRA--PRAHTVVGDL 399
+L L+ +D+G Y C A N ST + V I H V T R+ P + V
Sbjct: 2356 QLQALST--ADSGDYSCTARNAAG---STSVAFRVEI---HTVPTIRSGPPAVNVSVNQT 2407
Query: 400 LELHCESLRGSPPILYRFYHEDVTLGNSS-----APSGGGASFNLS-LTAEHSGNYSCDA 453
L C++ G P L + + V L S P G S + + A+ +G+Y C A
Sbjct: 2408 ALLPCQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLA 2463
Query: 454 DNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHE 513
N G+ G LRV P P + L CE+ P++ W+
Sbjct: 2464 SNSAGSDR-QGRDLRVLEP---PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2519
Query: 514 DDTLGNISAHSGGGASFNLSLTT----EHSGNYSCEADNGLGAQHSKV-VTLNVTGT-SR 567
+ + N L T + S + C N +G H VT++V T +
Sbjct: 2520 QKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2579
Query: 568 NRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSH-SPSECQEPSSSR 626
++T T + +VL+ A + +++A + L A G+ SPS E +
Sbjct: 2580 DQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ---LGARGSGYRVSPSGALEIGQAL 2636
Query: 627 P 627
P
Sbjct: 2637 P 2637
Score = 68.6 bits (166), Expect = 2e-11
Identities = 84/323 (26%), Positives = 128/323 (39%), Gaps = 24/323 (7%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRS-QIRVQRVPVSNVNLEIRPTGGQLIEGE 303
L+I D G Y C V S + R Q+RV P + E TG + +
Sbjct: 183 LRITGSHVGDEGRYQC----VAFSPAGQQARDFQLRVHAPPTIWGSNE---TGEVAVMED 235
Query: 304 NMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLA-ELHVLTVKESDAGRYYCAADN 362
++V + A+G T +W K+G + K + +L + + SDAG Y C A N
Sbjct: 236 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 295
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDV 422
R+ V +P + R V G + L C + RG P ++HE +
Sbjct: 296 AVGAAEKA-TRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVA-RGHPSPTLSWHHEGL 353
Query: 423 TLG--NSSAPSGGGASFNLSLTAE-HSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLT 479
+ N S G+ L E SG YSC A + G L+ +V V P
Sbjct: 354 PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGE-----AVLQYSVEVQVPPQL 408
Query: 480 LRAPG---AQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSL 534
L A G +VG LEL C++ P + W + + L + S G +
Sbjct: 409 LVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHV 468
Query: 535 TTEHSGNYSCEADNGLGAQHSKV 557
+HSG ++C+A N G ++V
Sbjct: 469 ELDHSGLFACQATNEAGTAGAEV 491
Score = 65.1 bits (157), Expect = 2e-10
Identities = 128/506 (25%), Positives = 191/506 (37%), Gaps = 54/506 (10%)
Query: 75 TEPGNYQC---KTRGSSLSDAVHVEFSPDWLILQALH-PVFEGDNVILRCQGKDNKNTHQ 130
++ G Y C G D V P ++ + L+ V ++V L CQ
Sbjct: 761 SDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVL 820
Query: 131 KVYYKDGKQL---PNSYNLEKITVNSVSR----DNSKYHCTAYRKFYILDIEVTSKPLNI 183
++KDG+ L P + + V R D Y C A + + K N+
Sbjct: 821 S-WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-----AGHSEKHYNL 874
Query: 184 QVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL---GLGWS 240
V + P+ + + T EG P L+CE + P + S +D Q L G G
Sbjct: 875 NVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFP-----KISWRKDGQPLPGEGAGLQ 929
Query: 241 RSPR----LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTG 296
L + G+Y CE V + S Q+ V VP PT
Sbjct: 930 HVSAVGRLLYLGQAQLAQEGTYTCECSNV---VGNSSQDLQLEVH-VPPQIAGPREPPTQ 985
Query: 297 GQLIEGENMVLICSVAQGSGTVTFSWHKEGRV--RSLGRKTQRSLLAELHVLTVKESDAG 354
+++ L C+ A G T +W ++G+ LG + Q + LHV + + G
Sbjct: 986 VSVVQDGVATLECN-ATGKPPPTVTWERDGQPVGAELGLQLQNQGQS-LHVERAQAAHTG 1043
Query: 355 RYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDL---LELHCESLRGSP 411
RY C A+N+ + ++V +P P L + L L L CE++ G P
Sbjct: 1044 RYSCVAENL-AGRAERKFELSVLVP---PELIGDLDPLTNITAALHSPLTLLCEAM-GIP 1098
Query: 412 PILYRFY--HEDVTLGNSSAPSGGGASFNLSLTAEH-SGNYSCDADNGLGAQHSHGVSLR 468
P R++ E V+ G + GG ++ T E SG YSC A N G + S+
Sbjct: 1099 PPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG-EARRNFSVE 1157
Query: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAH--SGG 526
V VP S L + + G L C P L WF + L AH S
Sbjct: 1158 VLVPPSIENEDLEEV-IKVLDGQTAHLMCNVTGHPQPKLTWF-KDGRPLARGDAHHISPD 1215
Query: 527 GASFN-LSLTTEHSGNYSCEADNGLG 551
G L +G+YSC A N +G
Sbjct: 1216 GVLLQVLQANLSSAGHYSCIAANAVG 1241
Score = 64.3 bits (155), Expect = 4e-10
Identities = 92/321 (28%), Positives = 131/321 (40%), Gaps = 25/321 (7%)
Query: 244 RLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGE 303
+L+I ED+G+Y C + S ++ ++ VQ PV L T EG
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKT---RLVVQVPPVIENGLPDLST----TEGS 2771
Query: 304 NMVLICSVAQGSGTVTFSWHKEGR-VRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADN 362
+ L C A+GS +W K+G+ V K EL V ++ DAG Y C A+N
Sbjct: 2772 HAFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 2830
Query: 363 VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPP--ILYRFYHE 420
+ RV + I V PV T +GD L L C + RGSP I +
Sbjct: 2831 A---VGRARRRVHLTILVL-PVFTTLPGDRSLRLGDRLWLRCAA-RGSPTPRIGWTVNDR 2885
Query: 421 DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSR-PVLT 479
VT G S GG +++ E SG Y C A+N +G + VS V V PVL
Sbjct: 2886 PVTEGVSEQ-DGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSF---VHVKEAPVLQ 2939
Query: 480 LRAPGAQAV-VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTT-E 537
A VG ++L C P ++W G+ H S + T +
Sbjct: 2940 GEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERD 2999
Query: 538 HSGNYSCEADNGLGAQHSKVV 558
+G Y C A+N +G V+
Sbjct: 3000 DAGRYQCLAENEMGVAKKVVI 3020
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/348 (25%), Positives = 137/348 (39%), Gaps = 33/348 (9%)
Query: 227 SLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVS 286
SL+ + + + +S P LQI + D G Y C + KR + ++ V
Sbjct: 550 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE-SKREVALKVLVPP---- 604
Query: 287 NVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE-LHV 345
N+E P ++E ++ L C +A G SW K + S S+ L +
Sbjct: 605 --NIEPGPVNKAVLENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRI 661
Query: 346 LTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCE 405
+ SDAG Y C A NV ST +R +R+ V + + +V + L C
Sbjct: 662 EQAQLSDAGSYRCVASNVAG---STELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 718
Query: 406 SLRGSPPILYRFYHEDVTLGNSSAPSG--------GGASFNL-SLTAEHSGNYSCDADNG 456
+ P L + +D GN +P+G GG L S A SG YSC A +
Sbjct: 719 ATGAPSPTL--MWLKD---GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSA 773
Query: 457 LGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDT 516
+G + V L+V +P P + V + + L C+S P+L W+
Sbjct: 774 VG-EDRQDVVLQVHMP---PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPL 829
Query: 517 LGNISAH-SGGGASFNLS-LTTEHSGNYSCEADNGLGAQHSKVVTLNV 562
H S A + +G+Y+CEA N G K LNV
Sbjct: 830 EPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAG-HSEKHYNLNV 876
Score = 60.1 bits (144), Expect = 7e-09
Identities = 131/588 (22%), Positives = 218/588 (37%), Gaps = 83/588 (14%)
Query: 55 DTYWYHDEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLI--------LQA 106
DTY +LK+ + Q + G Y C S+ + FS + L+ L+
Sbjct: 1116 DTYLLAGGWMLKMTQTQEQ--DSGLYSCLA--SNEAGEARRNFSVEVLVPPSIENEDLEE 1171
Query: 107 LHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQL---------PNSYNLEKITVNSVSRD 157
+ V +G L C + + ++KDG+ L P+ L+ + N S
Sbjct: 1172 VIKVLDGQTAHLMCNVTGHPQP-KLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 1230
Query: 158 NSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIE------GSPMTLTC 211
+ Y C A V K + Q+ L +L + + E +P++L C
Sbjct: 1231 H--YSCIAANA-------VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLIC 1281
Query: 212 ETQLSPQRPDVQLQ-----FSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVT 266
E P P++ F R+ Q L + LQI ED+G Y C VT
Sbjct: 1282 EALAFPS-PNITWMKDGAPFEASRNIQLL----PGTHGLQILNAQKEDAGQYTC---VVT 1333
Query: 267 HSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE---GENMVLICSVAQGSGTVTFSWH 323
+ + + + V P + + + G + ++ + L C + T W+
Sbjct: 1334 NELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY 1392
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVKE---SDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
K+G+ + + Q +L E +L ++ SD+GRY C A NV + + P+
Sbjct: 1393 KDGQPVTPSSRLQ--VLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPM 1450
Query: 381 SHPVLTFRA-----PRAHTVVGDLLE-----------LHCESLRGSPPILYRFYHED--V 422
V F A R G + E L+C++ PP L +Y ED +
Sbjct: 1451 FQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPL 1509
Query: 423 TLGNSSAPSGGGASFNLSLT-AEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLR 481
+ G+ + GG + L AE++G YSC A N +G H L +T PV
Sbjct: 1510 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL 1569
Query: 482 APGAQAVVGDLLELHCESLRGSFPILYWFYH--EDDTLGNISAHSGGGASFNLSLTTEHS 539
+ L C +L P + W + + G + +
Sbjct: 1570 VEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADA 1629
Query: 540 GNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVL 587
+Y C A+N G+ K+ TL V R GL +T ++ S + L
Sbjct: 1630 ASYMCVAENQAGSA-EKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSL 1675
Score = 51.6 bits (122), Expect = 3e-06
Identities = 80/335 (23%), Positives = 133/335 (39%), Gaps = 51/335 (15%)
Query: 157 DNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLH----PVLRASSSTP----IEGSPMT 208
D +Y C A+ P Q ++ L P + S+ T +E +
Sbjct: 192 DEGRYQCVAF------------SPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQ 239
Query: 209 LTCETQLSPQRPDVQLQFSLFRDSQTLGLG----WSRSPR-LQIPAMWTEDSGSYWCEVE 263
L CE + P P++ + F+D L ++R R LQ+ + D+G Y C+
Sbjct: 240 LLCEARGVPT-PNI----TWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKAS 294
Query: 264 TVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWH 323
+ +K + VP + RP + + G + L C VA+G + T SWH
Sbjct: 295 NAVGAAEKATRLDVY----VPPTIEGAGGRPYVVKAVAGRPVALEC-VARGHPSPTLSWH 349
Query: 324 KEGRVRSLGRKTQRSLLAELHVLTVK---ESDAGRYYCAADNVHSPILSTWIRVTVRIPV 380
EG + + L + VL ++ E+ +G Y C A SP ++ +V + V
Sbjct: 350 HEG--LPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS---SPAGEAVLQYSVEVQV 404
Query: 381 SHPVLTFRA-PRAHTVVGDLLELHCESLRGSPPILYRFYHED---VTLGNSSAPSGGGAS 436
+L + T+VG LEL C++ GSP ++ L S G
Sbjct: 405 PPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPTIQWLQNGRPAEELAGVQVASQGTTL 463
Query: 437 FNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ +HSG ++C A N G + G + V+V
Sbjct: 464 HIDHVELDHSGLFACQATNEAG---TAGAEVEVSV 495
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/375 (23%), Positives = 143/375 (38%), Gaps = 38/375 (10%)
Query: 197 SSSTPIEGSPMTLTCETQLSPQ------RPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAM 250
S+ T +P L CE SP+ + +L F L + + L S L + A
Sbjct: 2489 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL----LPSNALLLTAP 2544
Query: 251 WTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICS 310
+DS + C V++ + + Q+ V P + T + +VL C
Sbjct: 2545 GPQDSAQFEC---VVSNEVGEAHRLYQVTVHVPPT----IADDQTDFTVTMMAPVVLTCH 2597
Query: 311 VAQGSGTVTFSWHKEG-RVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILS 369
+ G T SW K G ++ + G + S L + AGRY C+A N + +
Sbjct: 2598 -STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARN-SAGVAH 2655
Query: 370 TWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLR-GSPPILYRFYHEDVTLGNSS 428
+ +TV+ + PV+ V + + L CE+ P I ++ +V G S+
Sbjct: 2656 KHVFLTVQ---ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST 2712
Query: 429 APSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAV 488
GG + E +GNY C A N G+ L V VP PV+ P
Sbjct: 2713 QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVP---PVIENGLPDLSTT 2768
Query: 489 VGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSG------GGASFNLSLTTEHSGNY 542
G L C++ P + W D +S G G +L + +G Y
Sbjct: 2769 EGSHAFLPCKARGSPEPNITW----DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTY 2824
Query: 543 SCEADNGLGAQHSKV 557
+C A+N +G +V
Sbjct: 2825 TCTAENAVGRARRRV 2839
Score = 46.6 bits (109), Expect = 8e-05
Identities = 86/333 (25%), Positives = 124/333 (37%), Gaps = 49/333 (14%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
LQ+ A+ T DSG Y C T ++ S+ ++ + VP + P + +
Sbjct: 2355 LQLQALSTADSGDYSC---TARNAAGSTSVAFRVEIHTVPT----IRSGPPAVNVSVNQT 2407
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAE--LHVLTVKESDAGRYYCAADN 362
+L C A G SW K+ RV R + +L E L + V DAG Y C A N
Sbjct: 2408 ALLPCQ-ADGVPAPLVSWRKD-RVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASN 2465
Query: 363 -VHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE- 420
S +RV + P P + AHT L CE+ GSP L ++ +
Sbjct: 2466 SAGSDRQGRDLRV-LEPPAIAPSPSNLTLTAHTPA----LLPCEA-SGSPKPLVVWWKDG 2519
Query: 421 ---DVTLGNSS---APSGGGASFNLSLTA---EHSGNYSCDADNGLGAQHSHGVSLRVTV 471
D L + PS L LTA + S + C N +G H +VTV
Sbjct: 2520 QKLDFRLQQGAYRLLPSNA-----LLLTAPGPQDSAQFECVVSNEVGEAHR---LYQVTV 2571
Query: 472 PVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFN 531
V + + ++ ++ L C S P + W G G G +
Sbjct: 2572 HVPPTIADDQTDFTVTMMAPVV-LTCHSTGIPAPTVSW-----SKAGAQLGARGSGYRVS 2625
Query: 532 LSLTTE-------HSGNYSCEADNGLGAQHSKV 557
S E H+G Y+C A N G H V
Sbjct: 2626 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHV 2658
Score = 45.8 bits (107), Expect = 1e-04
Identities = 57/248 (22%), Positives = 93/248 (37%), Gaps = 32/248 (12%)
Query: 230 RDSQTLGLGWSRSPR--------------LQIPAMWTEDSGSYWCEVETVTHSIKKRSLR 275
R S T +GW+ + R LQ A+ EDSG+Y C E + + +
Sbjct: 2871 RGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAE---NRVGRTQAV 2927
Query: 276 SQIRVQRVPVSN---VNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLG 332
S + V+ PV + + P GG + L C V +G W K+G
Sbjct: 2928 SFVHVKEAPVLQGEAFSYLVEPVGGSI------QLDC-VVRGDPVPDIHWIKDGLPLRGS 2980
Query: 333 RKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRA 392
+ L + + DAGRY C A+N + +V + + S PV
Sbjct: 2981 HLRHQLQNGSLTIRRTERDDAGRYQCLAENE----MGVAKKVVILVLQSAPVFQVEPQDM 3036
Query: 393 HTVVGDLLELHCESL-RGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSC 451
GD + L C++ +P I + + + G+ + ++ +G Y C
Sbjct: 3037 TVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDC 3096
Query: 452 DADNGLGA 459
A N LG+
Sbjct: 3097 VAHNLLGS 3104
Score = 39.7 bits (91), Expect = 0.010
Identities = 87/354 (24%), Positives = 131/354 (37%), Gaps = 46/354 (12%)
Query: 245 LQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGEN 304
L + + DSG Y C V S + + +P S + E+ + ++ E+
Sbjct: 753 LTLASARASDSGRYSC----VAVSAVGEDRQDVVLQVHMPPSILGEELNVS---VVANES 805
Query: 305 MVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESD---AGRYYCAAD 361
+ L C + SW K+GR L + L A+ +L V +D AG Y C A
Sbjct: 806 VALECQ-SHAMPPPVLSWWKDGR--PLEPRPGVHLSADKALLQVDRADVWDAGHYTCEAL 862
Query: 362 NV--HSPI---LSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYR 416
N HS L+ W+ + SH LT R G L CE RG P
Sbjct: 863 NQAGHSEKHYNLNVWVAPVFPLRESH-TLTVRE-------GHPTRLSCEC-RGVPFPKIS 913
Query: 417 FYHEDVTLGNSSA-----PSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTV 471
+ + L A + G + G Y+C+ N +G S + L V V
Sbjct: 914 WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG-NSSQDLQLEVHV 972
Query: 472 PVSRPVLTLRAPGAQ-AVVGD-LLELHCESLRGSFPILYWFYHEDDTLG---NISAHSGG 526
P + R P Q +VV D + L C + P + W + +G + + G
Sbjct: 973 PPQ--IAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW-ERDGQPVGAELGLQLQNQG 1029
Query: 527 GASFNLSLTTEHSGNYSCEADNGLGAQHSK-----VVTLNVTGTSRNRTGLTAA 575
+ H+G YSC A+N G K +V + G T +TAA
Sbjct: 1030 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAA 1083
Score = 36.6 bits (83), Expect = 0.086
Identities = 112/468 (23%), Positives = 180/468 (38%), Gaps = 78/468 (16%)
Query: 140 LPNSYNLEKITVNSVSRDNSKYHCT-------AYRKFYILDIEVTSKPLNIQVQELFLHP 192
LP ++ L+ +N+ D +Y C A + +++ + S + + E+ +
Sbjct: 1309 LPGTHGLQ--ILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKE 1366
Query: 193 VLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLG-------LGWSRSPRL 245
V +ST +TL CE+ P P ++ ++D Q + LG R L
Sbjct: 1367 VKTKVNST------LTLECESWAVPP-PTIRW----YKDGQPVTPSSRLQVLGEGRL--L 1413
Query: 246 QIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRV----QRVPVSNVNLEI-----RPTG 296
QI DSG Y C V T + I+V Q+V + EI G
Sbjct: 1414 QIQPTQVSDSGRYLC-VATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARG 1472
Query: 297 G-----QLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLT---V 348
G +++E L C +W++E + S G + S+L VL V
Sbjct: 1473 GVTEYREIVENNPAYLYCDT-NAIPPPDLTWYREDQPLSAGDEV--SVLQGGRVLQIPLV 1529
Query: 349 KESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVL---TFRAPRAHTV-VGDLLELHC 404
+ +AGRY C A N + W+ + + ++ PV+ T TV + L C
Sbjct: 1530 RAENAGRYSCKASN---EVGEDWLHYELLV-LTPPVILGDTEELVEEVTVNASSTVSLQC 1585
Query: 405 ESLRGSPPILYRFYHEDVTLGNSSAPSG------GGASFNLSLTAE--HSGNYSCDADNG 456
+L P + + G +PS G +S TAE + +Y C A+N
Sbjct: 1586 PALGNPVPTISWLQN-----GLPFSPSPRLQVLEDGQVLQVS-TAEVADAASYMCVAENQ 1639
Query: 457 LGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDD- 515
G+ +LRV VP L L A++ + L C+ P + W+
Sbjct: 1640 AGSAEKL-FTLRVQVPPRIAGLDLEQ--VTAILNSSVSLPCDVHAHPNPEVTWYKDSQAL 1696
Query: 516 TLGNISAHSGGGASFNLSLTT-EHSGNYSCEADNGLGAQHSKVVTLNV 562
+LG G + L SG Y+CEA N G + K+V L+V
Sbjct: 1697 SLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG-RDQKLVQLSV 1743
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 84.7 bits (208), Expect = 3e-16
Identities = 86/350 (24%), Positives = 141/350 (40%), Gaps = 45/350 (12%)
Query: 242 SPRLQIPAMWTEDSGSYWCEV-ETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLI 300
S LQI + ED GSY C VTH +K + ++ V R +V++ + PT Q +
Sbjct: 173 SGNLQILNVSLEDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVHI-LHPTHSQAL 231
Query: 301 E--GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYC 358
+ V + V G W K+G+ + G +R L + L +V +D+G Y C
Sbjct: 232 AVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRR-LYSHLATDSVDPADSGNYSC 290
Query: 359 AADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFY 418
A N + V V + H ++ +G + C+ + G+P ++
Sbjct: 291 MAGNKSGDVKYVTYMVNV---LEHASISKGLQDQIVSLGATVHFTCD-VHGNPAPNCTWF 346
Query: 419 HEDVTLGNSSAPSGGGASFNLS-LTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPV 477
H + S+ G +S +T E G Y C ADNG+G HS G +PV
Sbjct: 347 HNAQPIHPSARHLTAGNGLKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIENDGGFKPV 406
Query: 478 LTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAH-------------- 523
+ A+ GD + L C + P++ W+ D+ G I++H
Sbjct: 407 IITAPVSAKVADGDFVTLSCNASGLPVPVIRWY----DSHGLITSHPSQVLRSKSRKSQL 462
Query: 524 ----------------SGGGASFNL-SLTTEHSGNYSCEADNGLGAQHSK 556
G +S ++ ++T EH+G Y CEA N G ++
Sbjct: 463 SRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAE 512
Score = 44.3 bits (103), Expect = 4e-04
Identities = 86/383 (22%), Positives = 139/383 (36%), Gaps = 61/383 (15%)
Query: 143 SYNLEKITVNSVSRDNSKYHCTAYRKF-YILDIE------VTSKPLNIQVQELFLHPVLR 195
S NL+ + V+ D Y C AY + L +E + S+P + V LHP
Sbjct: 173 SGNLQILNVSL--EDKGSYKCAAYNPVTHQLKVEPIGRKLLVSRPSSDDVH--ILHPT-H 227
Query: 196 ASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL--GLGWSRS-PRLQIPAMWT 252
+ + + SP+TL C P Q +D Q + G W R L ++
Sbjct: 228 SQALAVLSRSPVTLECVVSGVPAP-----QVYWLKDGQDIAPGSNWRRLYSHLATDSVDP 282
Query: 253 EDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIE-GENMVLICSV 311
DSG+Y C + +K + + ++ +S + Q++ G + C V
Sbjct: 283 ADSGNYSCMAGNKSGDVKYVTYMVNV-LEHASIS------KGLQDQIVSLGATVHFTCDV 335
Query: 312 AQGSGTVTFSW-HKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILST 370
G+ +W H + R ++ +TV+ D G Y C ADN + ST
Sbjct: 336 -HGNPAPNCTWFHNAQPIHPSARHLTAGNGLKISGVTVE--DVGMYQCVADNGIGFMHST 392
Query: 371 WIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFY--------HEDV 422
PV+ A GD + L C + G P + R+Y H
Sbjct: 393 GRLEIENDGGFKPVIITAPVSAKVADGDFVTLSCNA-SGLPVPVIRWYDSHGLITSHPSQ 451
Query: 423 TLGNSSAPS-------------------GGGASFNL-SLTAEHSGNYSCDADNGLGAQHS 462
L + S S G +S ++ ++T EH+G Y C+A N G +
Sbjct: 452 VLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQA 511
Query: 463 HGVSLRVTVPVSRPVLTLRAPGA 485
+ V + T+ P A
Sbjct: 512 EASLMVVPFETNTKAETVTLPDA 534
Score = 42.7 bits (99), Expect = 0.001
Identities = 66/264 (25%), Positives = 96/264 (36%), Gaps = 23/264 (8%)
Query: 302 GENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAAD 361
G +VL CS T SW G+ + + L +L++ S G Y C A+
Sbjct: 43 GGPVVLHCSAQPV--TTRISWLHNGKTLDGNLEHVKIHQGTLTILSLNSSLLGYYQCLAN 100
Query: 362 NVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLE---LHCESLRGSPPILYRFY 418
N I+S V+V + + F + H + + + C +P R+
Sbjct: 101 NSIGAIVSGPATVSVAV-----LGDFGSSTKHVITAEEKSAGFIGCRVPESNPKAEVRYK 155
Query: 419 HEDVTLGNSS-----APSGGGASFNLSLTAEHSGNYSCDADNGLGAQ---HSHGVSLRVT 470
L +S+ PSG N+SL E G+Y C A N + Q G L V+
Sbjct: 156 IRGKWLEHSTENYLILPSGNLQILNVSL--EDKGSYKCAAYNPVTHQLKVEPIGRKLLVS 213
Query: 471 VPVSRPVLTLRAPGAQAVV---GDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGG 527
P S V L +QA+ + L C P +YW D +
Sbjct: 214 RPSSDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYS 273
Query: 528 ASFNLSLTTEHSGNYSCEADNGLG 551
S+ SGNYSC A N G
Sbjct: 274 HLATDSVDPADSGNYSCMAGNKSG 297
>gi|132814489 low affinity immunoglobulin gamma Fc region receptor
III-B precursor [Homo sapiens]
Length = 233
Score = 84.3 bits (207), Expect = 4e-16
Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 20/198 (10%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
+LL LL+L ++ PKAV+ L P W + + + V L C ++S T W+H
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQG-AYSPEDNSTQWFH 62
Query: 61 DEKLLKIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+E L+ + D + + G Y+C+T S+LSD V +E WL+LQA VF E D
Sbjct: 63 NENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEED 122
Query: 115 NVILRCQGKDNKNTHQKVYYKDGKQLP-----NSYNLEKITVNSVSRDNSKYHCTAYRKF 169
+ LRC N H+ Y ++GK + +++ K T+ +D+ Y C +
Sbjct: 123 PIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATL----KDSGSYFC----RG 174
Query: 170 YILDIEVTSKPLNIQVQE 187
+ V+S+ +NI + +
Sbjct: 175 LVGSKNVSSETVNITITQ 192
Score = 38.9 bits (89), Expect = 0.017
Identities = 57/234 (24%), Positives = 97/234 (41%), Gaps = 32/234 (13%)
Query: 85 RGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN-- 142
R L AV V P W + V E D+V L+CQG + + ++ + + +
Sbjct: 19 RTEDLPKAV-VFLEPQW------YSVLEKDSVTLKCQGAYSPEDNSTQWFHNENLISSQA 71
Query: 143 -SYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTP 201
SY ++ TVN D+ +Y C ++ S P+ ++V +L +L+A
Sbjct: 72 SSYFIDAATVN----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVF 118
Query: 202 IEGSPMTLTCETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWC 260
E P+ L C + + V LQ R + + IP +DSGSY+C
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKDRKY------FHHNSDFHIPKATLKDSGSYFC 172
Query: 261 EVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
+ ++ ++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 173 RGLVGSKNVSSETVNITI-TQGLAVSTIS-SFSPPGYQVSFCLVMVLLFAVDTG 224
>gi|189083840 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 8/170 (4%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
+LL LL+L ++ PKAV+ L P W + + V L C ++S T W+H
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG-AYSPEDNSTQWFH 62
Query: 61 DEKLLKIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+E L+ + D + + G Y+C+T S+LSD V +E WL+LQA VF E D
Sbjct: 63 NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEED 122
Query: 115 NVILRCQGKDNKNTHQKVYYKDGK-QLPNSYNLEKITVNSVSRDNSKYHC 163
+ LRC N H+ Y ++GK + +N + + +D+ Y C
Sbjct: 123 PIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFC 172
Score = 34.7 bits (78), Expect = 0.33
Identities = 56/234 (23%), Positives = 97/234 (41%), Gaps = 32/234 (13%)
Query: 85 RGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN-- 142
R L AV V P W + V E D+V L+CQG + + ++ + + +
Sbjct: 19 RTEDLPKAV-VFLEPQW------YRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQA 71
Query: 143 -SYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTP 201
SY ++ TV+ D+ +Y C ++ S P+ ++V +L +L+A
Sbjct: 72 SSYFIDAATVD----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVF 118
Query: 202 IEGSPMTLTCETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWC 260
E P+ L C + + V LQ R + + IP +DSGSY+C
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKY------FHHNSDFYIPKATLKDSGSYFC 172
Query: 261 EVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
+ ++ ++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 173 RGLFGSKNVSSETVNITI-TQGLAVSTIS-SFFPPGYQVSFCLVMVLLFAVDTG 224
>gi|189083838 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform c precursor [Homo sapiens]
Length = 254
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 8/170 (4%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
+LL LL+L ++ PKAV+ L P W + + V L C ++S T W+H
Sbjct: 4 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG-AYSPEDNSTQWFH 62
Query: 61 DEKLLKIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+E L+ + D + + G Y+C+T S+LSD V +E WL+LQA VF E D
Sbjct: 63 NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEED 122
Query: 115 NVILRCQGKDNKNTHQKVYYKDGK-QLPNSYNLEKITVNSVSRDNSKYHC 163
+ LRC N H+ Y ++GK + +N + + +D+ Y C
Sbjct: 123 PIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFC 172
Score = 34.7 bits (78), Expect = 0.33
Identities = 56/234 (23%), Positives = 97/234 (41%), Gaps = 32/234 (13%)
Query: 85 RGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN-- 142
R L AV V P W + V E D+V L+CQG + + ++ + + +
Sbjct: 19 RTEDLPKAV-VFLEPQW------YRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQA 71
Query: 143 -SYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTP 201
SY ++ TV+ D+ +Y C ++ S P+ ++V +L +L+A
Sbjct: 72 SSYFIDAATVD----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVF 118
Query: 202 IEGSPMTLTCETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWC 260
E P+ L C + + V LQ R + + IP +DSGSY+C
Sbjct: 119 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKY------FHHNSDFYIPKATLKDSGSYFC 172
Query: 261 EVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
+ ++ ++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 173 RGLFGSKNVSSETVNITI-TQGLAVSTIS-SFFPPGYQVSFCLVMVLLFAVDTG 224
>gi|50726979 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
isoform a precursor [Homo sapiens]
Length = 290
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 8/170 (4%)
Query: 1 MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH 60
+LL LL+L ++ PKAV+ L P W + + V L C ++S T W+H
Sbjct: 40 LLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQG-AYSPEDNSTQWFH 98
Query: 61 DEKLLKIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGD 114
+E L+ + D + + G Y+C+T S+LSD V +E WL+LQA VF E D
Sbjct: 99 NESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEED 158
Query: 115 NVILRCQGKDNKNTHQKVYYKDGK-QLPNSYNLEKITVNSVSRDNSKYHC 163
+ LRC N H+ Y ++GK + +N + + +D+ Y C
Sbjct: 159 PIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFC 208
Score = 34.7 bits (78), Expect = 0.33
Identities = 56/234 (23%), Positives = 97/234 (41%), Gaps = 32/234 (13%)
Query: 85 RGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN-- 142
R L AV V P W + V E D+V L+CQG + + ++ + + +
Sbjct: 55 RTEDLPKAV-VFLEPQW------YRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQA 107
Query: 143 -SYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTP 201
SY ++ TV+ D+ +Y C ++ S P+ ++V +L +L+A
Sbjct: 108 SSYFIDAATVD----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVF 154
Query: 202 IEGSPMTLTCETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWC 260
E P+ L C + + V LQ R + + IP +DSGSY+C
Sbjct: 155 KEEDPIHLRCHSWKNTALHKVTYLQNGKGRKY------FHHNSDFYIPKATLKDSGSYFC 208
Query: 261 EVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
+ ++ ++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 209 RGLFGSKNVSSETVNITI-TQGLAVSTIS-SFFPPGYQVSFCLVMVLLFAVDTG 260
>gi|189083842 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform d precursor [Homo sapiens]
Length = 253
Score = 80.1 bits (196), Expect = 7e-15
Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 10/165 (6%)
Query: 6 LLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHDEKLL 65
LLL+++ G PKAV+ L P W + + V L C ++S T W+H+E L+
Sbjct: 10 LLLLVSAGMRTD--LPKAVVFLEPQWYRVLEKDSVTLKCQG-AYSPEDNSTQWFHNESLI 66
Query: 66 KIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGDNVILR 119
+ D + + G Y+C+T S+LSD V +E WL+LQA VF E D + LR
Sbjct: 67 SSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLR 126
Query: 120 CQGKDNKNTHQKVYYKDGK-QLPNSYNLEKITVNSVSRDNSKYHC 163
C N H+ Y ++GK + +N + + +D+ Y C
Sbjct: 127 CHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFC 171
Score = 34.3 bits (77), Expect = 0.42
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 31/224 (13%)
Query: 95 VEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN---SYNLEKITV 151
V P W + V E D+V L+CQG + + ++ + + + SY ++ TV
Sbjct: 27 VFLEPQW------YRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATV 80
Query: 152 NSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTC 211
+ D+ +Y C ++ S P+ ++V +L +L+A E P+ L C
Sbjct: 81 D----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRC 127
Query: 212 ETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIK 270
+ + V LQ R + + IP +DSGSY+C + ++
Sbjct: 128 HSWKNTALHKVTYLQNGKGRKY------FHHNSDFYIPKATLKDSGSYFCRGLFGSKNVS 181
Query: 271 KRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 182 SETVNITI-TQGLAVSTIS-SFFPPGYQVSFCLVMVLLFAVDTG 223
>gi|189083836 Fc fragment of IgG, low affinity IIIa, receptor
(CD16a) isoform b precursor [Homo sapiens]
Length = 289
Score = 80.1 bits (196), Expect = 7e-15
Identities = 52/165 (31%), Positives = 81/165 (49%), Gaps = 10/165 (6%)
Query: 6 LLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHDEKLL 65
LLL+++ G PKAV+ L P W + + V L C ++S T W+H+E L+
Sbjct: 46 LLLLVSAGMRTD--LPKAVVFLEPQWYRVLEKDSVTLKCQG-AYSPEDNSTQWFHNESLI 102
Query: 66 KIKH-----DKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVF-EGDNVILR 119
+ D + + G Y+C+T S+LSD V +E WL+LQA VF E D + LR
Sbjct: 103 SSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLR 162
Query: 120 CQGKDNKNTHQKVYYKDGK-QLPNSYNLEKITVNSVSRDNSKYHC 163
C N H+ Y ++GK + +N + + +D+ Y C
Sbjct: 163 CHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFC 207
Score = 34.3 bits (77), Expect = 0.42
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 31/224 (13%)
Query: 95 VEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPN---SYNLEKITV 151
V P W + V E D+V L+CQG + + ++ + + + SY ++ TV
Sbjct: 63 VFLEPQW------YRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATV 116
Query: 152 NSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTC 211
+ D+ +Y C ++ S P+ ++V +L +L+A E P+ L C
Sbjct: 117 D----DSGEYRCQT-------NLSTLSDPVQLEVHIGWL--LLQAPRWVFKEEDPIHLRC 163
Query: 212 ETQLSPQRPDVQ-LQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIK 270
+ + V LQ R + + IP +DSGSY+C + ++
Sbjct: 164 HSWKNTALHKVTYLQNGKGRKY------FHHNSDFYIPKATLKDSGSYFCRGLFGSKNVS 217
Query: 271 KRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQG 314
++ I Q + VS ++ P G Q+ MVL+ +V G
Sbjct: 218 SETVNITI-TQGLAVSTIS-SFFPPGYQVSFCLVMVLLFAVDTG 259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,561,716
Number of Sequences: 37866
Number of extensions: 1472154
Number of successful extensions: 7844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 295
Number of HSP's that attempted gapping in prelim test: 5628
Number of HSP's gapped (non-prelim): 1486
length of query: 734
length of database: 18,247,518
effective HSP length: 110
effective length of query: 624
effective length of database: 14,082,258
effective search space: 8787328992
effective search space used: 8787328992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.