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Search of human proteins with 21264332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264332 sialyltransferase 7A [Homo sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264332 sialyltransferase 7A [Homo sapiens] 1230 0.0
gi|192448440 sialyltransferase 7B [Homo sapiens] 252 6e-67
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 97 4e-20
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 97 4e-20
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 97 4e-20
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 97 4e-20
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 97 4e-20
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 97 4e-20
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 88 3e-17
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 88 3e-17
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 83 8e-16
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 81 2e-15
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 80 4e-15
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 80 7e-15
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 80 7e-15
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 79 9e-15
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 75 2e-13
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 74 4e-13
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 72 2e-12
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 70 7e-12
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 64 3e-10
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 62 2e-09
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 62 2e-09
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 60 4e-09
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 59 1e-08
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 59 1e-08
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 55 2e-07
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 54 5e-07
gi|13569938 sialyltransferase 7E [Homo sapiens] 50 8e-06
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 49 2e-05
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 1230 bits (3182), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLA 60
MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLA
Sbjct: 1 MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLA 60
Query: 61 KPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQ 120
KPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQ
Sbjct: 61 KPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQ 120
Query: 121 RAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTV 180
RAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTV
Sbjct: 121 RAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTV 180
Query: 181 SEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPF 240
SEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPF
Sbjct: 181 SEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPF 240
Query: 241 QSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPN 300
QSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPN
Sbjct: 241 QSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPN 300
Query: 301 LTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSL 360
LTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSL
Sbjct: 301 LTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSL 360
Query: 361 RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ 420
RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ
Sbjct: 361 RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ 420
Query: 421 SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR
Sbjct: 421 SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG
Sbjct: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
Query: 541 FITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN 600
FITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN
Sbjct: 541 FITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN 600
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 252 bits (644), Expect = 6e-67
Identities = 135/330 (40%), Positives = 190/330 (57%), Gaps = 9/330 (2%)
Query: 264 FEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAP 323
F+ K S G C + + + + LF ++ + L F + WDRL
Sbjct: 51 FQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKA 110
Query: 324 PFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEI 383
P+G+ L++ ++ ++ +L +CI CAVVGNGGILN S G I
Sbjct: 111 PYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPP-KCIRCAVVGNGGILNGSRQGPNI 169
Query: 384 DSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLH 443
D+HDYVFRL+GA+IKG+E+DVGT+TSFYGFT ++ SL+ N GF +VP G+D++Y+
Sbjct: 170 DAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIF 229
Query: 444 FLEGTRDYEWLEALLMNQTV---MSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMK 500
RDY L + ++ V + K RP F ++ LLHPDF+ Y+
Sbjct: 230 IPSDIRDYVMLRSAILGVPVPEGLDKG-----DRPHAYFGPEASASKFKLLHPDFISYLT 284
Query: 501 NRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKR 560
RFL+SK ++ +Y P+TGAL+LLTAL CDQVSAYGFIT + +FSDHY++ K
Sbjct: 285 ERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKP 344
Query: 561 LIFYINHDFKLEREVWKRLHDEGIIRLYQR 590
LIFY NHD LE +W+ LH GI++LYQR
Sbjct: 345 LIFYANHDLSLEAALWRDLHKAGILQLYQR 374
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 146 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 195
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 196 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 243
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 244 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 299
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 300 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 359
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 360 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 400
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 92 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 141
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 142 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 189
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 190 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 245
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 246 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 305
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 306 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 346
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 162 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 211
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 212 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 259
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 260 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 315
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 316 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 375
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 376 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 416
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 123 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 172
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 173 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 220
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 221 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 276
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 277 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 336
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 337 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 377
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 177 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 226
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 227 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 274
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 275 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 330
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 331 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 390
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 391 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 431
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 97.1 bits (240), Expect = 4e-20
Identities = 82/291 (28%), Positives = 136/291 (46%), Gaps = 50/291 (17%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 108 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 157
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 158 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 205
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
I G P + L L G + D++WL+ ++ + V + + FW A R
Sbjct: 206 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFW----KSVATR 261
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+L+P F++ + +G R PT G++ + AL CD+V+ G
Sbjct: 262 VPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAG 321
Query: 541 FITEGHERFSD----HYYDT--------SWKRLIFYINHDFKLEREVWKRL 579
F G++ + HYY+T SW H+ + E+E ++L
Sbjct: 322 F---GYDMSTPNAPLHYYETVRMAAIKESW-------THNIQREKEFLRKL 362
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 87.8 bits (216), Expect = 3e-17
Identities = 68/233 (29%), Positives = 111/233 (47%), Gaps = 32/233 (13%)
Query: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
S+ C CAVVGN G L S G EIDSHD+V R++ A G+E DVGT+T+ +
Sbjct: 136 SVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHH------- 188
Query: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEA 478
++ F+ LG +V + T D EW+ + + T+ + P A
Sbjct: 189 -----LVYPESFRE--LGDNVSMILVPFKTIDLEWVVSAITTGTISHTYI------PVPA 235
Query: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
+ + D+ L+ HP F++Y+ + +L+ H R P+TG L ++ ++ +CD+V
Sbjct: 236 -KIRVKQDKILIYHPAFIKYVFDNWLQ------GHGRY--PSTGILSVIFSMHVCDEVDL 286
Query: 539 YGFITEGHERFSDHYYDTSWKRLIFYIN--HDFKLEREVWKRLHDEGIIRLYQ 589
YGF + + HY++ + F HD E V L IR+++
Sbjct: 287 YGFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 87.8 bits (216), Expect = 3e-17
Identities = 68/233 (29%), Positives = 111/233 (47%), Gaps = 32/233 (13%)
Query: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
S+ C CAVVGN G L S G EIDSHD+V R++ A G+E DVGT+T+ +
Sbjct: 136 SVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHH------- 188
Query: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEA 478
++ F+ LG +V + T D EW+ + + T+ + P A
Sbjct: 189 -----LVYPESFRE--LGDNVSMILVPFKTIDLEWVVSAITTGTISHTYI------PVPA 235
Query: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
+ + D+ L+ HP F++Y+ + +L+ H R P+TG L ++ ++ +CD+V
Sbjct: 236 -KIRVKQDKILIYHPAFIKYVFDNWLQ------GHGRY--PSTGILSVIFSMHVCDEVDL 286
Query: 539 YGFITEGHERFSDHYYDTSWKRLIFYIN--HDFKLEREVWKRLHDEGIIRLYQ 589
YGF + + HY++ + F HD E V L IR+++
Sbjct: 287 YGFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 82.8 bits (203), Expect = 8e-16
Identities = 64/230 (27%), Positives = 106/230 (46%), Gaps = 17/230 (7%)
Query: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
SLRC C VVGNG L NS +G I+ +D V RL+ A + GYE DVG++T+ F S
Sbjct: 110 SLRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESA 169
Query: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEA 478
+ N D + D+ W+E +L ++ + K FW Q
Sbjct: 170 HFDPKVENN---------PDTLLVLVAFKAMDFHWIETILSDKKRVRKG-FW----KQPP 215
Query: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCD--QV 536
++ + +L+P F+ ++ L S + +PTTG L + AL LCD +
Sbjct: 216 LIWDVNPKQIRILNPFFMEIAADKLL-SLPMQQPRKIKQKPTTGLLAITLALHLCDLVHI 274
Query: 537 SAYGFITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIR 586
+ +G+ +++ + HYY+ + + H+ E KR+ + G I+
Sbjct: 275 AGFGYPDAYNKKQTIHYYEQITLKSMAGSGHNVSQEALAIKRMLEMGAIK 324
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 81.3 bits (199), Expect = 2e-15
Identities = 58/197 (29%), Positives = 99/197 (50%), Gaps = 30/197 (15%)
Query: 361 RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ 420
+C CAVVGN G L S GQ++D H+++ R++ A G+EQDVG+RT+ + F +
Sbjct: 148 QCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTTHH----FMYPE 203
Query: 421 SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR 480
S KN+P +V ++ D W+ + L S F + P ++F
Sbjct: 204 SA--------KNLP--ANVSFVLVPFKVLDLLWIASAL------STGQIRFTYAPVKSFL 247
Query: 481 EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG 540
+ ++ + +P F +Y+ +R+ H R P+TG L+L AL +CD+V+ YG
Sbjct: 248 R-VDKEKVQIYNPAFFKYIHDRWTEH------HGRY--PSTGMLVLFFALHVCDEVNVYG 298
Query: 541 FITEGHERFSDHYYDTS 557
F + + HY++ +
Sbjct: 299 FGADSRGNW-HHYWENN 314
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 80.5 bits (197), Expect = 4e-15
Identities = 72/241 (29%), Positives = 110/241 (45%), Gaps = 46/241 (19%)
Query: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ---S 421
CAVVGN GIL S GQEID D+VFR + A + +++DVG +T+ F L + +
Sbjct: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNN 221
Query: 422 LLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMN-QTVMSKNL--FWFRHRPQEA 478
LL + +R + L K L+G W+ A + +++ L F+ HR Q
Sbjct: 222 LLTIQDRNNFFLSLKK-------LDGA--ILWIPAFFFHTSATVTRTLVDFFVEHRGQ-- 270
Query: 479 FREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
+ L ++ H + RY KN+ L K L +TG L+ A +C+++
Sbjct: 271 LKVQLAWPGNIMQHVN--RYWKNKHLSPKRL----------STGILMYTLASAICEEIHL 318
Query: 539 YGFITEG-----HERFSDHYYD-------TSWKRLIFYINHDFKLEREVWKRLHDEGIIR 586
YGF G E HYYD T W+ +H E ++ R+H EG+ +
Sbjct: 319 YGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQE-----SHQLPAEFQLLYRMHGEGLTK 373
Query: 587 L 587
L
Sbjct: 374 L 374
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 79.7 bits (195), Expect = 7e-15
Identities = 68/272 (25%), Positives = 120/272 (44%), Gaps = 27/272 (9%)
Query: 321 FAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMG 380
+ PPFGF + + S VQ ++ P + L A C C V+G+GGIL+ +G
Sbjct: 135 YDPPFGFRKFS-SKVQTLLELLPEHDLPEHLKAKT------CRRCVVIGSGGILHGLELG 187
Query: 381 QEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVR 440
++ D V RL+ A ++GY + VG +T T + ++ +
Sbjct: 188 HTLNQFDVVIRLNSAPVEGYSEHVGNKT----------TIRMTYPEGAPLSDLEYYSNDL 237
Query: 441 YLHFLEGTRDYEWLEALLMNQTVMSKNLFWFR--HRPQEAFREALHMDRYLLLHPDFLRY 498
++ L + D+ WL+A++ +T+ FW R Q A + L + +L+P ++
Sbjct: 238 FVAVLFKSVDFNWLQAMVKKETLP----FWVRLFFWKQVAEKIPLQPKHFRILNPVIIKE 293
Query: 499 MKNRFLRSKTLDGAHWRIYR--PTTGALLLLTALQLCDQVSAYGFITE-GHERFSDHYYD 555
L+ W + PT G + ++ A LCD+VS GF + R HY+D
Sbjct: 294 TAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFD 353
Query: 556 TS-WKRLIFYINHDFKLEREVWKRLHDEGIIR 586
+ + F H+ E + +L EG+++
Sbjct: 354 SQCMAAMNFQTMHNVTTETKFLLKLVKEGVVK 385
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 79.7 bits (195), Expect = 7e-15
Identities = 68/272 (25%), Positives = 120/272 (44%), Gaps = 27/272 (9%)
Query: 321 FAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMG 380
+ PPFGF + + S VQ ++ P + L A C C V+G+GGIL+ +G
Sbjct: 158 YDPPFGFRKFS-SKVQTLLELLPEHDLPEHLKAKT------CRRCVVIGSGGILHGLELG 210
Query: 381 QEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVR 440
++ D V RL+ A ++GY + VG +T T + ++ +
Sbjct: 211 HTLNQFDVVIRLNSAPVEGYSEHVGNKT----------TIRMTYPEGAPLSDLEYYSNDL 260
Query: 441 YLHFLEGTRDYEWLEALLMNQTVMSKNLFWFR--HRPQEAFREALHMDRYLLLHPDFLRY 498
++ L + D+ WL+A++ +T+ FW R Q A + L + +L+P ++
Sbjct: 261 FVAVLFKSVDFNWLQAMVKKETLP----FWVRLFFWKQVAEKIPLQPKHFRILNPVIIKE 316
Query: 499 MKNRFLRSKTLDGAHWRIYR--PTTGALLLLTALQLCDQVSAYGFITE-GHERFSDHYYD 555
L+ W + PT G + ++ A LCD+VS GF + R HY+D
Sbjct: 317 TAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFD 376
Query: 556 TS-WKRLIFYINHDFKLEREVWKRLHDEGIIR 586
+ + F H+ E + +L EG+++
Sbjct: 377 SQCMAAMNFQTMHNVTTETKFLLKLVKEGVVK 408
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 79.3 bits (194), Expect = 9e-15
Identities = 72/247 (29%), Positives = 112/247 (45%), Gaps = 29/247 (11%)
Query: 349 QLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRT 408
+LL + P + TCA+VGN G+L NS GQEID+H +V R + A ++ Y +DVG +T
Sbjct: 141 ELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKT 200
Query: 409 SFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLM---NQTVMS 465
+ ++ L N ++ K ++ LH L G+ W+ A + + V
Sbjct: 201 DLVTMNPSVIQRAFEDLVNATWRE----KLLQRLHSLNGS--ILWIPAFMARGGKERVEW 254
Query: 466 KNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALL 525
N +H R A R LLH ++ +L +K I RPTTG L+
Sbjct: 255 VNELILKHHVN--VRTAYPSLR--LLHA-----VRGYWLTNKV------HIKRPTTGLLM 299
Query: 526 LLTALQLCDQVSAYGF----ITEGHERFSDHYYDT-SWKRLIFYINHDFKLEREVWKRLH 580
A + C Q+ YGF + + HYYD+ + H LE + K LH
Sbjct: 300 YTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLH 359
Query: 581 DEGIIRL 587
++G ++L
Sbjct: 360 EQGALKL 366
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 24/163 (14%)
Query: 303 LFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRC 362
+FLD +W R+ F PPFG + +L++ +++ V ++ L +L SLRC
Sbjct: 108 MFLDDSF---RKWARIREFVPPFGIKGQD-NLIKAILS----VTKEYRLTPALD--SLRC 157
Query: 363 ITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSL 422
C +VGNGG+L N +G ID +D V RL+ A +KG+E+DVG++T +L
Sbjct: 158 RRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKT------------TL 205
Query: 423 LILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTV 463
I G P + L L G + D++WL+ ++ + V
Sbjct: 206 RITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERV 248
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 73.9 bits (180), Expect = 4e-13
Identities = 58/211 (27%), Positives = 91/211 (43%), Gaps = 28/211 (13%)
Query: 359 SLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSL 418
++ C C VVGNGG+L N +G++IDS+D + R++ + G+E++VG RT+F F S+
Sbjct: 112 NIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESV 171
Query: 419 TQSLLILGNRGFKNVPLGKDVRYLHFLEGTR--DYEWLEALLMNQTVMSKNLFWFRHRPQ 476
P+ D L + D WL LLM + + N FW +
Sbjct: 172 FSD------------PIHNDPNTTVILTAFKPHDLRWLLELLMGDKI-NTNGFW----KK 214
Query: 477 EAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQV 536
A + +L P +R L + + + PTTG + + A +C +V
Sbjct: 215 PALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEV 274
Query: 537 SAYGFITEGHERFSD-----HYYDTSWKRLI 562
GF FSD HYY + L+
Sbjct: 275 HLAGF----KYNFSDLKSPLHYYGNATMSLM 301
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 71.6 bits (174), Expect = 2e-12
Identities = 68/245 (27%), Positives = 111/245 (45%), Gaps = 39/245 (15%)
Query: 356 PAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTA 415
P + R TCAVVGN GIL +S G+EIDSH++V R + A + + DVGT++ F
Sbjct: 133 PMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDF----- 187
Query: 416 FSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRD-YEWLEALLMNQTVMSKNLFWFRHR 474
++ S++ GF+N +++H L D W+ A ++ K++ W
Sbjct: 188 ITMNPSVVQRAFGGFRNE--SDREKFVHRLSMLNDSVLWIPAFMVKGG--EKHVEWV--- 240
Query: 475 PQEAFREALHMDRYLLLHPDF-----LRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTA 529
AL + L + + + ++ +L +K I RP+TG L+ A
Sbjct: 241 ------NALILKNKLKVRTAYPSLRLIHAVRGYWLTNKV------PIKRPSTGLLMYTLA 288
Query: 530 LQLCDQVSAYGF----ITEGHERFSDHYYDTSWKRLIFYIN---HDFKLEREVWKRLHDE 582
+ CD++ YGF + HYYD R ++ N H LE + LH+
Sbjct: 289 TRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYR--YFSNASPHRMPLEFKTLNVLHNR 346
Query: 583 GIIRL 587
G ++L
Sbjct: 347 GALKL 351
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 69.7 bits (169), Expect = 7e-12
Identities = 71/234 (30%), Positives = 101/234 (43%), Gaps = 40/234 (17%)
Query: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKG-YEQDVGTRTSFYGFTAFSLTQSLL 423
CAVVGNGGILN S G EID D+VFR + G +DVG++T+ ++ S++
Sbjct: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNL-----VTINPSII 240
Query: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR--- 480
L K + FLE Y LL F FR +F+
Sbjct: 241 TLKYGNLKE-------KKALFLEDIATYGDAFFLL--------PAFSFRANTGTSFKVYY 285
Query: 481 ---EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVS 537
E+ + L HP +L+ + F R+K + YR +TG ++ A++LC V
Sbjct: 286 TLEESKARQKVLFFHPKYLKDLA-LFWRTKGVTA-----YRLSTGLMITSVAVELCKNVK 339
Query: 538 AYGF----ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRL 587
YGF T S HYYD + F H E +LH +GI++L
Sbjct: 340 LYGFWPFSKTVEDIPVSHHYYDNKLPKHGF---HQMPKEYSQILQLHMKGILKL 390
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 64.3 bits (155), Expect = 3e-10
Identities = 64/239 (26%), Positives = 97/239 (40%), Gaps = 48/239 (20%)
Query: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLS-GALIKGYEQDVGTRTSFYGFTAFSLTQSLL 423
CAVVGNGGIL NS G+EI+S D+VFR + + + Y DVG +T +T+
Sbjct: 164 CAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVVTVNPSIITER-- 221
Query: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREAL 483
H LE R + + + F+ + R
Sbjct: 222 ------------------FHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKY 263
Query: 484 HMDRY------LLLHPDFL----RYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLC 533
+D + HP +L RY + +R+K R +TG +L+ AL+LC
Sbjct: 264 VLDDFESPQAVYYFHPQYLVNVSRYWLSLGVRAK----------RISTGLILVTAALELC 313
Query: 534 DQVSAYGF----ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLY 588
++V +GF + + HYYD R F H E + LH GI+R++
Sbjct: 314 EEVHLFGFWAFPMNPSGLYITHHYYDNVKPRPGF---HAMPSEIFNFLHLHSRGILRVH 369
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/220 (27%), Positives = 100/220 (45%), Gaps = 37/220 (16%)
Query: 343 PPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQ 402
P VP QL P G LR +CAVV + G + NS +G+EIDSHD V R + A +GYE+
Sbjct: 281 PAVPLSQLH----PRG-LR--SCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333
Query: 403 DVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQT 462
DVG +T T + +L + F + L KDV + + +
Sbjct: 334 DVGNKT-----TIRIINSQILTNPSHHFIDSSLYKDVILVAW---------------DPA 373
Query: 463 VMSKNL-FWFRHRPQEAFREAL-HMDR-----YLLLHPDFLRYMKNRFLRSKTLDGAHWR 515
S NL W++ F + H R + +LHP F+ + + ++ T + +
Sbjct: 374 PYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWD-IIQENTKEKI--Q 430
Query: 516 IYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYD 555
P++G + +L + +C +V Y +I + HY++
Sbjct: 431 PNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHE 470
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/220 (27%), Positives = 100/220 (45%), Gaps = 37/220 (16%)
Query: 343 PPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQ 402
P VP QL P G LR +CAVV + G + NS +G+EIDSHD V R + A +GYE+
Sbjct: 281 PAVPLSQLH----PRG-LR--SCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333
Query: 403 DVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQT 462
DVG +T T + +L + F + L KDV + + +
Sbjct: 334 DVGNKT-----TIRIINSQILTNPSHHFIDSSLYKDVILVAW---------------DPA 373
Query: 463 VMSKNL-FWFRHRPQEAFREAL-HMDR-----YLLLHPDFLRYMKNRFLRSKTLDGAHWR 515
S NL W++ F + H R + +LHP F+ + + ++ T + +
Sbjct: 374 PYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWD-IIQENTKEKI--Q 430
Query: 516 IYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYD 555
P++G + +L + +C +V Y +I + HY++
Sbjct: 431 PNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHE 470
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 60.5 bits (145), Expect = 4e-09
Identities = 67/237 (28%), Positives = 109/237 (45%), Gaps = 28/237 (11%)
Query: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLS-GALIKGYEQDVGTRTSFYGFTAFSLTQSLL 423
CAVVGNGGIL S G++ID ++V R + L Y +DVG+++ +T +
Sbjct: 138 CAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQL-------VTANPS 190
Query: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREAL 483
I+ R F+N+ + + Y ++ A M +T +L R +
Sbjct: 191 IIRQR-FQNLLWSRKTFVDNMKIYNHSYIYMPAFSM-KTGTEPSL-----RVYYTLSDVG 243
Query: 484 HMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGF-- 541
L +P+FLR + +F +S+ G H + R +TG L+ AL LC++V+ YGF
Sbjct: 244 ANQTVLFANPNFLRSI-GKFWKSR---GIHAK--RLSTGLFLVSAALGLCEEVAIYGFWP 297
Query: 542 --ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTA 596
+ + S HYYD F+ + L ++W LH G +R+ P T+
Sbjct: 298 FSVNMHEQPISHHYYDNVLPFSGFHAMPEEFL--QLW-YLHKIGALRMQLDPCEDTS 351
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/289 (24%), Positives = 120/289 (41%), Gaps = 60/289 (20%)
Query: 330 LNYSLVQKVVTRFP--------PVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQ 381
+N S+V+ VT FP +P++ + + P G CAVV + G L +S +G+
Sbjct: 148 VNVSMVE--VTDFPFNTSEWEGYLPKESIRTKAGPWGR-----CAVVSSAGSLKSSQLGR 200
Query: 382 EIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRY 441
EID HD V R +GA ++QDVGT+T+ L S L+ + F KD Y
Sbjct: 201 EIDDHDAVLRFNGAPTANFQQDVGTKTT------IRLMNSQLVTTEKRFL-----KDSLY 249
Query: 442 LHFLEGTRDYEWLEALLMNQTVMSKNL-FWFRHRPQEAFREALHMDRYLLLHPDFLRYMK 500
+ ++ + +V ++ W+++ F + Y LHP+ +
Sbjct: 250 NEGI----------LIVWDPSVYHSDIPKWYQNPDYNFFN---NYKTYRKLHPN-----Q 291
Query: 501 NRFLRSKTLDGAHWRIYR-----------PTTGALLLLTALQLCDQVSAYGFITEGHERF 549
++ + W I + P++G L ++ + LCDQV Y F+ +
Sbjct: 292 PFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTD 351
Query: 550 SDHYYDTSW-KRLIFYINHDFKLEREVWKRLH---DEGIIRLYQRPGPG 594
+YY + H E+ + K L+ DE I L + PG
Sbjct: 352 VCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPG 400
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 58.9 bits (141), Expect = 1e-08
Identities = 71/289 (24%), Positives = 120/289 (41%), Gaps = 60/289 (20%)
Query: 330 LNYSLVQKVVTRFP--------PVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQ 381
+N S+V+ VT FP +P++ + + P G CAVV + G L +S +G+
Sbjct: 148 VNVSMVE--VTDFPFNTSEWEGYLPKESIRTKAGPWGR-----CAVVSSAGSLKSSQLGR 200
Query: 382 EIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRY 441
EID HD V R +GA ++QDVGT+T+ L S L+ + F KD Y
Sbjct: 201 EIDDHDAVLRFNGAPTANFQQDVGTKTT------IRLMNSQLVTTEKRFL-----KDSLY 249
Query: 442 LHFLEGTRDYEWLEALLMNQTVMSKNL-FWFRHRPQEAFREALHMDRYLLLHPDFLRYMK 500
+ ++ + +V ++ W+++ F + Y LHP+ +
Sbjct: 250 NEGI----------LIVWDPSVYHSDIPKWYQNPDYNFFN---NYKTYRKLHPN-----Q 291
Query: 501 NRFLRSKTLDGAHWRIYR-----------PTTGALLLLTALQLCDQVSAYGFITEGHERF 549
++ + W I + P++G L ++ + LCDQV Y F+ +
Sbjct: 292 PFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTD 351
Query: 550 SDHYYDTSW-KRLIFYINHDFKLEREVWKRLH---DEGIIRLYQRPGPG 594
+YY + H E+ + K L+ DE I L + PG
Sbjct: 352 VCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPG 400
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/67 (49%), Positives = 43/67 (64%), Gaps = 7/67 (10%)
Query: 343 PPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQ 402
P VP QL P G LR +CAVV + G + NS +G+EIDSHD V R + A +GYE+
Sbjct: 281 PAVPLSQLH----PRG-LR--SCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333
Query: 403 DVGTRTS 409
DVG +T+
Sbjct: 334 DVGNKTT 340
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 53.5 bits (127), Expect = 5e-07
Identities = 50/196 (25%), Positives = 85/196 (43%), Gaps = 29/196 (14%)
Query: 362 CITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQS 421
C +CAVV + G + S +G EIDS + VFR++ A G+E DVG R++ S T
Sbjct: 73 CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRST---LRVVSHTSV 129
Query: 422 LLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFRE 481
L+L N Y H+ + RD ++ V + R +R
Sbjct: 130 PLLLRN-------------YSHYFQKARDTLYM--------VWGQGRHMDRVLGGRTYRT 168
Query: 482 ALHMDRY---LLLHPDFLRYMK--NRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQV 536
L + R L ++ R M ++ + +T +TG ++ AL+LC+++
Sbjct: 169 LLQLTRMYPGLQVYTFTERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEI 228
Query: 537 SAYGFITEGHERFSDH 552
YG +++ + R H
Sbjct: 229 VVYGMVSDSYCREKSH 244
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 49.7 bits (117), Expect = 8e-06
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 27/203 (13%)
Query: 360 LRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLT 419
+ C CA+V + G L +S G +ID + V R++ A +GY +DVG RTS S+
Sbjct: 91 MHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQ 150
Query: 420 QSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAF 479
+ IL NR L+ +GT W + M + + Q
Sbjct: 151 R---ILRNRH----------DLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLP 197
Query: 480 R-EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSA 538
R +A + R+ +L D L K + + + W +TG + AL+LCD+++
Sbjct: 198 RLKAFMITRHKMLQFDEL--FKQETGKDRKISNT-WL----STGWFTMTIALELCDRINV 250
Query: 539 YGFI------TEGHERFSDHYYD 555
YG + H HYY+
Sbjct: 251 YGMVPPDFCRDPNHPSVPYHYYE 273
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 48.5 bits (114), Expect = 2e-05
Identities = 53/218 (24%), Positives = 83/218 (38%), Gaps = 31/218 (14%)
Query: 360 LRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLT 419
L C CA+V N G + +G EID ++R++ A KGYE+DVG T S T
Sbjct: 75 LDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTM---IRVVSHT 131
Query: 420 QSLLILGNRG--FKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQE 477
L+L N FK V + F +D + ++ +TV
Sbjct: 132 SVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVYNMLKKTV-------------- 177
Query: 478 AFREALHMDRYLLLHPD-FLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQV 536
++ + + + + + Y F + D Y +TG L A+ C +
Sbjct: 178 ----GIYPNAQIYVTTEKRMSYCDGVFKKETGKDRVQSGSYL-STGWFTFLLAMDACYGI 232
Query: 537 SAYGFI------TEGHERFSDHYYDTSWKRLIFYINHD 568
YG I TEG+ + HYY+ Y H+
Sbjct: 233 HVYGMINDTYCKTEGYRKVPYHYYEQGRDECDEYFLHE 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,236,161
Number of Sequences: 37866
Number of extensions: 1198735
Number of successful extensions: 6459
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 5790
Number of HSP's gapped (non-prelim): 760
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.