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Search of human proteins with 20270327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270327 transmembrane 4 L six family member 18 [Homo
sapiens]
(201 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens] 412 e-115
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens] 192 1e-49
gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens] 152 2e-37
gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens] 129 2e-30
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens] 77 1e-14
gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens] 48 5e-06
gi|91106202 G protein-coupled receptor 22 [Homo sapiens] 34 0.096
gi|52627166 olfactory receptor, family 52, subfamily H, member 1... 30 1.1
gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide ... 30 1.4
gi|239753676 PREDICTED: hypothetical protein [Homo sapiens] 29 2.4
gi|239748302 PREDICTED: hypothetical protein [Homo sapiens] 29 2.4
gi|239742200 PREDICTED: hypothetical protein [Homo sapiens] 29 2.4
gi|187828568 DNA-directed DNA polymerase delta 2 [Homo sapiens] 29 2.4
gi|5453924 DNA-directed DNA polymerase delta 2 [Homo sapiens] 29 2.4
gi|10092687 NIPA-like domain containing 3 [Homo sapiens] 28 4.0
gi|100913194 six transmembrane epithelial antigen of the prostat... 28 4.0
gi|100913196 six transmembrane epithelial antigen of the prostat... 28 4.0
gi|239749659 PREDICTED: hypothetical protein XP_002347139 [Homo ... 28 6.9
gi|239743930 PREDICTED: hypothetical protein XP_002342992 [Homo ... 28 6.9
>gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]
Length = 201
Score = 412 bits (1059), Expect = e-115
Identities = 201/201 (100%), Positives = 201/201 (100%)
Query: 1 MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM 60
MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM
Sbjct: 1 MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM 60
Query: 61 LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY 120
LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY
Sbjct: 61 LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY 120
Query: 121 CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV 180
CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV
Sbjct: 121 CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV 180
Query: 181 VMQLSKILCGSYSVIFQPGII 201
VMQLSKILCGSYSVIFQPGII
Sbjct: 181 VMQLSKILCGSYSVIFQPGII 201
>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
Length = 202
Score = 192 bits (489), Expect = 1e-49
Identities = 88/187 (47%), Positives = 125/187 (66%), Gaps = 1/187 (0%)
Query: 5 KCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVT 64
KC C+ L+ LAL I NILLYFPNG+T YAS N L+ +VW+F GI G++ML+
Sbjct: 5 KCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLMLLPA 64
Query: 65 TVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYC-RT 123
V + LE ++ CC ENC K+ L S++ + +GIA SGYC++++ALGL +GP C +
Sbjct: 65 FVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPLCLDS 124
Query: 124 LDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRVVMQ 183
L W Y F T G++L D+S W +C EP H+VEWN+ LFSIL+ L G++ I+CLI+V+
Sbjct: 125 LGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQVING 184
Query: 184 LSKILCG 190
+ +CG
Sbjct: 185 VLGGICG 191
>gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]
Length = 202
Score = 152 bits (384), Expect = 2e-37
Identities = 76/188 (40%), Positives = 114/188 (60%), Gaps = 7/188 (3%)
Query: 7 GGCLSCL---LIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIV 63
GGC CL LIPLA + + NILL+FP G+ ++ L+ +W+F GI SG++M+
Sbjct: 4 GGCARCLGGTLIPLAFFGFLANILLFFPGGKV-IDDNDHLSQEIWFFGGILGSGVLMIFP 62
Query: 64 TTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRT 123
V L L+NN+ CC +E C K++ S IF+ +G +GY +ISA+ + +GP C
Sbjct: 63 ALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLM 122
Query: 124 LDG-WEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRVVM 182
+ W Y F G +L D ++W +C EP +VV WN+ LFSIL+ + G+Q+++C I+VV
Sbjct: 123 ANSTWGYPFHD--GDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVN 180
Query: 183 QLSKILCG 190
L LCG
Sbjct: 181 GLLGTLCG 188
>gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]
Length = 197
Score = 129 bits (323), Expect = 2e-30
Identities = 67/190 (35%), Positives = 100/190 (52%), Gaps = 3/190 (1%)
Query: 1 MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM 60
M + KC C+ LI L L I+ N LL PNG+TS+ ++N L+ VW G G+M+
Sbjct: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
Query: 61 LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY 120
L + CC + C + L S+ S+ G+ + YCL +S GL GP
Sbjct: 61 LCPGIAAVRAGGKG---CCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPR 117
Query: 121 CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV 180
C W Y FE TAG +L + ++W +C P VV WN+ LFS+L+ S L++++C I++
Sbjct: 118 CLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQL 177
Query: 181 VMQLSKILCG 190
V + CG
Sbjct: 178 VNATIGVFCG 187
>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
Length = 209
Score = 76.6 bits (187), Expect = 1e-14
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 19/200 (9%)
Query: 3 SRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLI 62
SR C L L AL++ N+ L PN +Y L + G+ G+M+L
Sbjct: 11 SRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVL- 69
Query: 63 VTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSG--YCLVISALGLVQGPY 120
T +L+ Y C + +T L S G+A G C V S + L GP+
Sbjct: 70 -TAAILISLMGWRYGCFSKSGLCRSVLTALL----SGGLALLGALICFVTSGVALKDGPF 124
Query: 121 C-------RTLDGWEYAF---EGTAGRFLTDSSIWIQ-CLEPAHVVEWNIILFSILITLS 169
C W+Y + + + +L D S+W CLEP+ V W++ LFS L+ +S
Sbjct: 125 CMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCIS 184
Query: 170 GLQVIICLIRVVMQLSKILC 189
LQ+++ ++ V+ L + C
Sbjct: 185 LLQLLLVVVHVINSLLGLFC 204
>gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens]
Length = 229
Score = 48.1 bits (113), Expect = 5e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 12/118 (10%)
Query: 6 CGGCLSC----LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMML 61
C G SC LL+ L L ++ I L + S N ++ + W+F GI +G+M +
Sbjct: 4 CEGWTSCNGFSLLVLLLLGVVLNAIPLIVSLVEEDQFSQNPISCFEWWFPGIIGAGLMAI 63
Query: 62 IVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGP 119
TT+ L + C C+ + LS +FS + + + YC++IS L++GP
Sbjct: 64 PATTMSLTARK----RAC----CNNRTGMFLSSLFSVITVIGALYCMLISIQALLKGP 113
>gi|91106202 G protein-coupled receptor 22 [Homo sapiens]
Length = 433
Score = 33.9 bits (76), Expect = 0.096
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 19/135 (14%)
Query: 13 LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72
L I L L S + ++LY + SN +T + + I G + L + +LL LE+
Sbjct: 50 LEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLES 109
Query: 73 NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRTLDGWEYAFE 132
N CC E C + F+S+ A + + + + + P R L
Sbjct: 110 NTALICCFHEAC---------VSFASVSTAINVFAITLDRYDISVKPANRIL-------- 152
Query: 133 GTAGR-FLTDSSIWI 146
T GR + SIWI
Sbjct: 153 -TMGRAVMLMISIWI 166
>gi|52627166 olfactory receptor, family 52, subfamily H, member 1
[Homo sapiens]
Length = 320
Score = 30.4 bits (67), Expect = 1.1
Identities = 15/41 (36%), Positives = 28/41 (68%), Gaps = 4/41 (9%)
Query: 87 KYVTLLS---IIFSSLGIAFSGYCLVISALGLVQG-PYCRT 123
+Y T+L+ II S++GI+F +C+++ + L+ P+CRT
Sbjct: 139 RYTTILTPKTIIKSAMGISFRSFCIILPDVFLLTCLPFCRT 179
>gi|9845285 cytochrome P450, family 26, subfamily b, polypeptide 1
[Homo sapiens]
Length = 512
Score = 30.0 bits (66), Expect = 1.4
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 165 LITLSGLQVIICLIRVVMQLSKILCGSYSVIFQ 197
L TLSGL+ + C+I+ VM+L + G Y + Q
Sbjct: 345 LDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQ 377
>gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 29.3 bits (64), Expect = 2.4
Identities = 35/166 (21%), Positives = 65/166 (39%), Gaps = 29/166 (17%)
Query: 13 LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72
+L+ L + S+ ++ +FP S K W C L +TT +L+L
Sbjct: 11 ILVTLGILSVCSGVIAFFP------VFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
Query: 73 NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRTLDGWEYAFE 132
+ +++Y+ + F L I I+ + GPYC Y+F
Sbjct: 65 YREW--------TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCF------YSFS 110
Query: 133 GTAGRFLTDSSIW---------IQCLEPAHVVEWNIILFSILITLS 169
G AG ++ + C++P H E+++ L ++ + LS
Sbjct: 111 GIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLS 156
>gi|239748302 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 29.3 bits (64), Expect = 2.4
Identities = 35/166 (21%), Positives = 65/166 (39%), Gaps = 29/166 (17%)
Query: 13 LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72
+L+ L + S+ ++ +FP S K W C L +TT +L+L
Sbjct: 11 ILVTLGILSVCSGVIAFFP------VFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
Query: 73 NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRTLDGWEYAFE 132
+ +++Y+ + F L I I+ + GPYC Y+F
Sbjct: 65 YREW--------TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCF------YSFS 110
Query: 133 GTAGRFLTDSSIW---------IQCLEPAHVVEWNIILFSILITLS 169
G AG ++ + C++P H E+++ L ++ + LS
Sbjct: 111 GIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLS 156
>gi|239742200 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 29.3 bits (64), Expect = 2.4
Identities = 35/166 (21%), Positives = 65/166 (39%), Gaps = 29/166 (17%)
Query: 13 LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72
+L+ L + S+ ++ +FP S K W C L +TT +L+L
Sbjct: 11 ILVTLGILSVCSGVIAFFP------VFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLA 64
Query: 73 NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPYCRTLDGWEYAFE 132
+ +++Y+ + F L I I+ + GPYC Y+F
Sbjct: 65 YREW--------TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCF------YSFS 110
Query: 133 GTAGRFLTDSSIW---------IQCLEPAHVVEWNIILFSILITLS 169
G AG ++ + C++P H E+++ L ++ + LS
Sbjct: 111 GIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLS 156
>gi|187828568 DNA-directed DNA polymerase delta 2 [Homo sapiens]
Length = 469
Score = 29.3 bits (64), Expect = 2.4
Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 111 SALGLVQGPYCRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNI 159
S L LV PY T+DG F GT+G+ ++D + + ++EW +
Sbjct: 323 STLQLVTNPYQATIDG--VRFLGTSGQNVSDIFRYSSMEDHLEILEWTL 369
>gi|5453924 DNA-directed DNA polymerase delta 2 [Homo sapiens]
Length = 469
Score = 29.3 bits (64), Expect = 2.4
Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 111 SALGLVQGPYCRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNI 159
S L LV PY T+DG F GT+G+ ++D + + ++EW +
Sbjct: 323 STLQLVTNPYQATIDG--VRFLGTSGQNVSDIFRYSSMEDHLEILEWTL 369
>gi|10092687 NIPA-like domain containing 3 [Homo sapiens]
Length = 406
Score = 28.5 bits (62), Expect = 4.0
Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 7/98 (7%)
Query: 13 LLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLIVTTVLLVLEN 72
L++PL+ S+I + ++ + + + L YV + F G + +V T LLV
Sbjct: 101 LIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYV-----LSFVGCGLAVVGTYLLVTFA 155
Query: 73 NNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVI 110
N+++ EN ++ V+ +++ + I +CL++
Sbjct: 156 PNSHEKMTGENVTRHLVSWPFLLYMLVEIIL--FCLLL 191
>gi|100913194 six transmembrane epithelial antigen of the prostate 2
isoform a [Homo sapiens]
Length = 490
Score = 28.5 bits (62), Expect = 4.0
Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 29/121 (23%)
Query: 47 VWYFE-----GICFSGIMMLIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGI 101
VW E GI G++ L+ T + + N N++ S I S+LG
Sbjct: 354 VWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWR-------------EFSFIQSTLGY 400
Query: 102 AFSGYCLVISALGLVQGPYCRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIIL 161
L+IS ++ + GW+ AFE RF T + + + P+ V+ IIL
Sbjct: 401 V----ALLISTFHVL-------IYGWKRAFEEEYYRFYTPPNFVLALVLPSIVILGKIIL 449
Query: 162 F 162
F
Sbjct: 450 F 450
>gi|100913196 six transmembrane epithelial antigen of the prostate 2
isoform a [Homo sapiens]
Length = 490
Score = 28.5 bits (62), Expect = 4.0
Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 29/121 (23%)
Query: 47 VWYFE-----GICFSGIMMLIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGI 101
VW E GI G++ L+ T + + N N++ S I S+LG
Sbjct: 354 VWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWR-------------EFSFIQSTLGY 400
Query: 102 AFSGYCLVISALGLVQGPYCRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIIL 161
L+IS ++ + GW+ AFE RF T + + + P+ V+ IIL
Sbjct: 401 V----ALLISTFHVL-------IYGWKRAFEEEYYRFYTPPNFVLALVLPSIVILGKIIL 449
Query: 162 F 162
F
Sbjct: 450 F 450
>gi|239749659 PREDICTED: hypothetical protein XP_002347139 [Homo
sapiens]
Length = 369
Score = 27.7 bits (60), Expect = 6.9
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 76 YKCCQSENCSKKYVTLLSIIFSSLG 100
Y QSE C K + LLS+IFSS G
Sbjct: 71 YVLSQSEICKGKNIFLLSLIFSSPG 95
>gi|239743930 PREDICTED: hypothetical protein XP_002342992 [Homo
sapiens]
Length = 369
Score = 27.7 bits (60), Expect = 6.9
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 76 YKCCQSENCSKKYVTLLSIIFSSLG 100
Y QSE C K + LLS+IFSS G
Sbjct: 71 YVLSQSEICKGKNIFLLSLIFSSPG 95
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.143 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,410,963
Number of Sequences: 37866
Number of extensions: 282471
Number of successful extensions: 796
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 779
Number of HSP's gapped (non-prelim): 20
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.