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Search of human proteins with 198442844
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
(4471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 8915 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2437 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 2323 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 2314 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2290 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2287 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 2284 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 2199 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2172 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 2159 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2093 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 2056 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 2012 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1450 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1344 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 1093 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 764 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 478 e-134
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 197 2e-49
gi|156104908 myosin heavy chain 6 [Homo sapiens] 55 1e-06
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 54 5e-06
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 53 6e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 52 1e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 1e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 1e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 51 2e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 51 2e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 51 3e-05
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 50 4e-05
gi|55770834 centromere protein F [Homo sapiens] 50 7e-05
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 8915 bits (23133), Expect = 0.0
Identities = 4471/4471 (100%), Positives = 4471/4471 (100%)
Query: 1 MVPEEVEVEIDEIPVLSEEGEEEEETYSQKVESVDKVRAKRVSLRTESLGQPLNREDEEM 60
MVPEEVEVEIDEIPVLSEEGEEEEETYSQKVESVDKVRAKRVSLRTESLGQPLNREDEEM
Sbjct: 1 MVPEEVEVEIDEIPVLSEEGEEEEETYSQKVESVDKVRAKRVSLRTESLGQPLNREDEEM 60
Query: 61 DKEISEKLPSKRTAKHIMEKMHLHMLCTPLPEEFLDQNVVFFLRNTKEAISEATDMKEAM 120
DKEISEKLPSKRTAKHIMEKMHLHMLCTPLPEEFLDQNVVFFLRNTKEAISEATDMKEAM
Sbjct: 61 DKEISEKLPSKRTAKHIMEKMHLHMLCTPLPEEFLDQNVVFFLRNTKEAISEATDMKEAM 120
Query: 121 EIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHRTSTTVGVTSGEVSNSSEHESDL 180
EIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHRTSTTVGVTSGEVSNSSEHESDL
Sbjct: 121 EIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHRTSTTVGVTSGEVSNSSEHESDL 180
Query: 181 PPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAA 240
PPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAA
Sbjct: 181 PPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAA 240
Query: 241 DPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLP 300
DPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLP
Sbjct: 241 DPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLP 300
Query: 301 IVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVV 360
IVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVV
Sbjct: 301 IVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVV 360
Query: 361 LDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQ 420
LDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQ
Sbjct: 361 LDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQ 420
Query: 421 SKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQI 480
SKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQI
Sbjct: 421 SKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQI 480
Query: 481 LEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFK 540
LEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFK
Sbjct: 481 LEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFK 540
Query: 541 IEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDR 600
IEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDR
Sbjct: 541 IEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDR 600
Query: 601 GQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGA 660
GQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGA
Sbjct: 601 GQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGA 660
Query: 661 VFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIG 720
VFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIG
Sbjct: 661 VFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIG 720
Query: 721 TLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNA 780
TLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNA
Sbjct: 721 TLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNA 780
Query: 781 DDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLT 840
DDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLT
Sbjct: 781 DDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLT 840
Query: 841 KVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETIL 900
KVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETIL
Sbjct: 841 KVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETIL 900
Query: 901 TAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYN 960
TAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYN
Sbjct: 901 TAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYN 960
Query: 961 DISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVA 1020
DISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVA
Sbjct: 961 DISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVA 1020
Query: 1021 YDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEE 1080
YDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEE
Sbjct: 1021 YDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEE 1080
Query: 1081 LYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYN 1140
LYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYN
Sbjct: 1081 LYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYN 1140
Query: 1141 LFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKR 1200
LFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKR
Sbjct: 1141 LFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKR 1200
Query: 1201 FYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE 1260
FYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE
Sbjct: 1201 FYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE 1260
Query: 1261 MSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYY 1320
MSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYY
Sbjct: 1261 MSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYY 1320
Query: 1321 LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD 1380
LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD
Sbjct: 1321 LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD 1380
Query: 1381 VLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDN 1440
VLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDN
Sbjct: 1381 VLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDN 1440
Query: 1441 TFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQL 1500
TFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQL
Sbjct: 1441 TFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQL 1500
Query: 1501 PEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDS 1560
PEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDS
Sbjct: 1501 PEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDS 1560
Query: 1561 KRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISA 1620
KRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISA
Sbjct: 1561 KRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISA 1620
Query: 1621 EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMV 1680
EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMV
Sbjct: 1621 EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMV 1680
Query: 1681 VLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNT 1740
VLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNT
Sbjct: 1681 VLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNT 1740
Query: 1741 VLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMG 1800
VLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMG
Sbjct: 1741 VLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMG 1800
Query: 1801 LNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGE 1860
LNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGE
Sbjct: 1801 LNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGE 1860
Query: 1861 GMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQ 1920
GMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQ
Sbjct: 1861 GMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQ 1920
Query: 1921 EISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKT 1980
EISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKT
Sbjct: 1921 EISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKT 1980
Query: 1981 LAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMN 2040
LAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMN
Sbjct: 1981 LAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMN 2040
Query: 2041 LPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMF 2100
LPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMF
Sbjct: 2041 LPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMF 2100
Query: 2101 ETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTT 2160
ETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTT
Sbjct: 2101 ETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTT 2160
Query: 2161 RDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIR 2220
RDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIR
Sbjct: 2161 RDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIR 2220
Query: 2221 LQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSL 2280
LQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSL
Sbjct: 2221 LQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSL 2280
Query: 2281 FEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLEC 2340
FEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLEC
Sbjct: 2281 FEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLEC 2340
Query: 2341 YFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFD 2400
YFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFD
Sbjct: 2341 YFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFD 2400
Query: 2401 NKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTS 2460
NKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTS
Sbjct: 2401 NKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTS 2460
Query: 2461 KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVF 2520
KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVF
Sbjct: 2461 KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVF 2520
Query: 2521 MDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNE 2580
MDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNE
Sbjct: 2521 MDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNE 2580
Query: 2581 VDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIV 2640
VDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIV
Sbjct: 2581 VDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIV 2640
Query: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700
QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET
Sbjct: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700
Query: 2701 DKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQ 2760
DKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQ
Sbjct: 2701 DKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQ 2760
Query: 2761 EILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTA 2820
EILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTA
Sbjct: 2761 EILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTA 2820
Query: 2821 SCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTS 2880
SCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTS
Sbjct: 2821 SCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTS 2880
Query: 2881 GIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTL 2940
GIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTL
Sbjct: 2881 GIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTL 2940
Query: 2941 RTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSV 3000
RTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSV
Sbjct: 2941 RTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSV 3000
Query: 3001 DHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQ 3060
DHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQ
Sbjct: 3001 DHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQ 3060
Query: 3061 LDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAME 3120
LDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAME
Sbjct: 3061 LDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAME 3120
Query: 3121 KAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELN 3180
KAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELN
Sbjct: 3121 KAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELN 3180
Query: 3181 WKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKF 3240
WKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKF
Sbjct: 3181 WKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKF 3240
Query: 3241 VEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAI 3300
VEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAI
Sbjct: 3241 VEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAI 3300
Query: 3301 LEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLS 3360
LEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLS
Sbjct: 3301 LEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLS 3360
Query: 3361 YEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSV 3420
YEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSV
Sbjct: 3361 YEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSV 3420
Query: 3421 QNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFL 3480
QNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFL
Sbjct: 3421 QNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFL 3480
Query: 3481 FRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVF 3540
FRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVF
Sbjct: 3481 FRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVF 3540
Query: 3541 GKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLREL 3600
GKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLREL
Sbjct: 3541 GKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLREL 3600
Query: 3601 ATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFF 3660
ATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFF
Sbjct: 3601 ATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFF 3660
Query: 3661 VLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLF 3720
VLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLF
Sbjct: 3661 VLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLF 3720
Query: 3721 ERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILL 3780
ERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILL
Sbjct: 3721 ERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILL 3780
Query: 3781 SEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDR 3840
SEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDR
Sbjct: 3781 SEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDR 3840
Query: 3841 VYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSG 3900
VYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSG
Sbjct: 3841 VYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSG 3900
Query: 3901 FGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHP 3960
FGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHP
Sbjct: 3901 FGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHP 3960
Query: 3961 DFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPL 4020
DFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPL
Sbjct: 3961 DFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPL 4020
Query: 4021 VYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSL 4080
VYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSL
Sbjct: 4021 VYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSL 4080
Query: 4081 KYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKE 4140
KYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKE
Sbjct: 4081 KYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKE 4140
Query: 4141 KFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYI 4200
KFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYI
Sbjct: 4141 KFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYI 4200
Query: 4201 GQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRAL 4260
GQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRAL
Sbjct: 4201 GQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRAL 4260
Query: 4261 AGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEP 4320
AGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEP
Sbjct: 4261 AGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEP 4320
Query: 4321 SVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSG 4380
SVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSG
Sbjct: 4321 SVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSG 4380
Query: 4381 LYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM 4440
LYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM
Sbjct: 4381 LYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM 4440
Query: 4441 GVGLVFEADLFTTRHISHWVLQGVCLTLNSD 4471
GVGLVFEADLFTTRHISHWVLQGVCLTLNSD
Sbjct: 4441 GVGLVFEADLFTTRHISHWVLQGVCLTLNSD 4471
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2437 bits (6315), Expect = 0.0
Identities = 1481/4378 (33%), Positives = 2359/4378 (53%), Gaps = 246/4378 (5%)
Query: 196 IRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINW 255
IR+ F ++ KF + + T +LEG L +P ++ + + D E V LE +I+W
Sbjct: 193 IRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHW 252
Query: 256 LNQISTAVEAQ-LKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDS 314
QI + AQ +T + GPL EIEFWR R LS + +Q V+ V ++ + S
Sbjct: 253 TRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKS 312
Query: 315 MLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMV 374
+A + ++ +A N+ FLS ++ ++ + + +P ++S +R++
Sbjct: 313 SYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDIS-SKLPKLISLIRII 371
Query: 375 WIISRHYNKDERMIPLMERIA--------WEIAER--------------VCRVVNLRTLF 412
W+ S HYN ER+ L ++ WE ++ ++ + +F
Sbjct: 372 WVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIF 431
Query: 413 KENR---ASAQSKTLEARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMAT 469
+N + + L+ +NT W + Y RA I K L T + T
Sbjct: 432 HKNLHTLRAVRGGILDVKNTC--WHEDYNKFRAGI-------------KDLEVMTQNLIT 476
Query: 470 ----ICQDLSDVLQILEEFYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFS 525
+ +D+ + +L+ F+ + E T D K +D
Sbjct: 477 SAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVD---------------------- 514
Query: 526 IKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFRIKHT 585
Y++ F E+ + +N+ +N + P L +G W L RI
Sbjct: 515 -------LYML--FNSELAL--VNR--ERNKKWPDLEPYVAQYSGKARWVHILRRRIDRV 561
Query: 586 ILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTK 645
+ + G+E Y ++ + + E + +++W ++ + LL
Sbjct: 562 MTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRI 621
Query: 646 SSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYT 705
S E+ + +NF +L + E Y E+L F P NVA + +
Sbjct: 622 SQ---------EKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILR 672
Query: 706 AGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDY-ITGCKQ 764
+ + Y+ +I L+ E L K+ + L + G K+L+W G + IT C+
Sbjct: 673 ENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRI 732
Query: 765 AIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASD 824
K + +V++ + I R + L + + +L EF E RA+
Sbjct: 733 HASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDL----EFEEDQREHRAAV 788
Query: 825 VDHMVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFN 884
++ + + ++T + + + Y ++ + + L + +L +
Sbjct: 789 QQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELS 848
Query: 885 SLILGNV-----PLFHTETIL------TAPEIILHPN-------TNEIDKMCFHCVRNCV 926
I G+ PLF IL + ++ P N+I F +
Sbjct: 849 KAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFC 908
Query: 927 EITKHFV-RWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILIN 985
+ R ++ I+ ++ E+ + + + ++ N +++
Sbjct: 909 HLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQN-------------- 954
Query: 986 LMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEH 1045
YL+ W YR +W+++K + ++ PP ++ + Y+++A V + + +
Sbjct: 955 ---YLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQ 1011
Query: 1046 CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDL 1105
+ L HL ++ ++ W LL E A L LH ++ A+ + + P TLE+L
Sbjct: 1012 FVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEEL 1071
Query: 1106 KFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDS 1165
L + ++ +E + + E++ + Y + D+ E++D + W
Sbjct: 1072 GVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTL 1131
Query: 1166 VNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG--PGSVG--DDLDKGVELLG 1221
++ + L K F +++ + + F +G +VG LD+ ++
Sbjct: 1132 LDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRA 1191
Query: 1222 VYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEW 1281
+ +A E+ AN +F + +L ++KE+ L+ I+E+ + EW
Sbjct: 1192 ML---MAMREEENSLRANLG-IFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEW 1247
Query: 1282 SQTLWINLNVQILQEGIEGFLRALRKLPRPV--RGLSVTYYLEAKMKAFKDSIPLLLDLK 1339
++ L + ++ G R L KL + R + +K++ FK ++PL+ DL+
Sbjct: 1248 KTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLR 1307
Query: 1340 NEALRDRHWKELMEKTSVFFEM-TETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKA 1398
N ALR+RHW ++ ++ F+ +E+FTLE + + + +H + + EI +A KE+AIE A
Sbjct: 1308 NPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVA 1367
Query: 1399 VKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQ 1458
++ I TW+ + +V Y R L +E+ Q+L+DN L ++ SRFV F +
Sbjct: 1368 LQNIAKTWDVTQLDIVPYKDKGHHR---LRGTEEVFQALEDNQVALSTMKASRFVKAFEK 1424
Query: 1459 TVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIM 1518
V WE+ LSLI EVIE+ + VQR+WMYLE+IF+G DIR QLP E+ FD ++ +K IM
Sbjct: 1425 DVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIM 1484
Query: 1519 GETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLS 1578
KD R P L L ++ LE QKSL+ YL++KR+ FPRF+F+S+D+LL
Sbjct: 1485 DRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLE 1544
Query: 1579 ILGSS-DPLCVQEHMIKMYDNIASLRFND--GDSGEKLVSAMISAEGEVMEFRKILRAEG 1635
ILG S +P VQ H+ K +DNI LR G S + M S +GE ++F + EG
Sbjct: 1545 ILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEG 1604
Query: 1636 RVEDWMTAVLNEMRRTNRLITKE---AIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWE 1692
VE W+ V MR T R + + A+ ++ R + W+ + G VV+ ASQ+ WT +
Sbjct: 1605 PVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDK--WVKEWAGQVVITASQIQWTAD 1662
Query: 1693 VEDVFHKA-QKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDI 1751
V A ++ +K+ +K + +++ I L+K R K ++ I++HARD+
Sbjct: 1663 VTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDV 1722
Query: 1752 VDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLT 1811
++ + +++ FDW SQLRFYW+++ D+ IRQ F Y YEY+G +GRLVITPLT
Sbjct: 1723 LEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLT 1782
Query: 1812 DRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIF 1871
DR Y+TLT AL ++ GG+P GPAGTGKTET KDL KALG+ +V NC EG+DY+++G+++
Sbjct: 1783 DRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMY 1842
Query: 1872 SGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIF 1931
SGLAQ GAWGCFDEFNRI+ VLSV++ QI I +AL LT F F+G EI+L GIF
Sbjct: 1843 SGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIF 1902
Query: 1932 ITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKL 1991
ITMNPGYAGRTELPE++K++FRP+ ++VPD I EI+LF EGF K LAKK+ LY L
Sbjct: 1903 ITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSL 1962
Query: 1992 AREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPL 2051
A +QLS+Q HYDFGLRAL S+L AG+ +R DL ++ VL+ ++RDMN+ K D PL
Sbjct: 1963 AVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPL 2022
Query: 2052 FLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMV 2111
F ++ DLFP ++ P + Y + VEQ + + G P + KV Q++ET +RH+TM+
Sbjct: 2023 FNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMI 2082
Query: 2112 VGPTRGGKSVV-------INTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWT 2164
VG T GK+ +++LC+A + + LNPKA+S+ ELYG D +T +WT
Sbjct: 2083 VGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWT 2142
Query: 2165 DGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAH 2224
DG+LS++ R +K + K+ILFDG VD LW+ENMNSVMDDN++LTL NGERI +
Sbjct: 2143 DGILSSVMRTACAD-EKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQ 2201
Query: 2225 CALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKY 2284
+LLFEV DL ASPATVSRCGMVY D +L ++PY + W+ + P K E L +FEK
Sbjct: 2202 VSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRP-KAEVEPLQRMFEKL 2260
Query: 2285 VPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALL--EGEIEDLD------ 2336
+ ++ + + K +VP + + +T L K+ AL E + D
Sbjct: 2261 INKMLAF---------KKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYVT 2311
Query: 2337 LLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYD 2396
++E F+ ++ S+ AS+ E+GR + D Y++ + EG + N T+Y+
Sbjct: 2312 MVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI--------EGSFPNKD-------TVYE 2356
Query: 2397 FHFDNKRNQWVPWSKLVPE-YIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
+ D K W + +P+ + + P F I+V TVDT R +++ +V + P++ VG
Sbjct: 2357 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG 2416
Query: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
GT KT+ Q+ L++L VL+VN S++TTS ++Q +E+ VEKRTK Y P GK
Sbjct: 2417 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK 2476
Query: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
++ FMDD+NMP D +G+Q P+ L++L ++ G+ YDR K+ K IR++ +AAMG G
Sbjct: 2477 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYIREMFLMAAMGPPG 2535
Query: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLAL 2635
GGR + PR S F++ N+ FP++ + I+ +++ F E + + +T TL +
Sbjct: 2536 GGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDM 2595
Query: 2636 YKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDR 2695
Y +VQ PTP+K HY+FNLRD+S+VF G++ N + T + + R+W +EC RVF DR
Sbjct: 2596 YNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDR 2655
Query: 2696 LISETDKQ----LVQQHIGS---LVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYED 2748
L+ D + ++ +GS L H + P +FGDF EP++YED
Sbjct: 2656 LVDAADTEAFMGIISDKLGSFFDLTFHHLCPS-----KRPPIFGDFLK-----EPKVYED 2705
Query: 2749 IQDYEAAKALFQEILEEYNESNT--KMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGG 2806
+ D K + + L EYN S + M LVLF +A+EH+TR+ R+I RG+ LLVG+GG
Sbjct: 2706 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG 2765
Query: 2807 SGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVA 2866
SG+QSL+RLA+ F+I +++ Y + FR+D+K LY + G+E K F+F D +A
Sbjct: 2766 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA 2825
Query: 2867 EEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANN 2926
+E FLE INN+L+SG VP L+ +E E I S I +A + + + +S++ Y + + NN
Sbjct: 2826 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN 2885
Query: 2927 LHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENI 2986
LHIVL +SP+GD R W R +P +VN T I+WF WP +AL VA+ L + ENI
Sbjct: 2886 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI 2945
Query: 2987 ENVVKHV-VLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCK 3045
V + V +H SV YSQ+ L +LRR NYVTP YL+ ++ Y KLL EK Q +AQ
Sbjct: 2946 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN 3005
Query: 3046 RLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEE 3105
+L GL K+ E ++ ++ +L + K +AE CE L I A+E++K
Sbjct: 3006 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA 3065
Query: 3106 KAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQT 3165
+ +I + A+ L E +P LE A L+ L+K D+ EI+S+ +PP QV+
Sbjct: 3066 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI 3125
Query: 3166 VCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225
V + ++I++G E W AK + + NF++SL+ D D+I+ +K I + +
Sbjct: 3126 VMQAVMILRG-NEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD 3184
Query: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285
+ VS A + +V A+ Y ++R ++PKR ++ + L Q +L +
Sbjct: 3185 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV 3244
Query: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345
++LE L +Y+ + +K++L++++E ME +L A L+SGL E RW + L
Sbjct: 3245 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL 3304
Query: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEI 3405
L+GDCLL AAFLSY G F +RDE+VN+IW I E ++P S F +++ L + ++
Sbjct: 3305 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV 3364
Query: 3406 SRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDF 3465
W QGLP D S +NGI+ TR +R+ L IDPQ QAL WIK E L++ D+
Sbjct: 3365 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY 3424
Query: 3466 LKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLY 3525
L+ LE +I +G P L ++V EY+DP ++ +L K++ GR + +GDKEV+Y++NFR Y
Sbjct: 3425 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY 3484
Query: 3526 LNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSEN 3585
+ TKL+NP YSP K ++N+ V +GLE QLL ++V ER ELEEQ++ L+ +
Sbjct: 3485 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG 3544
Query: 3586 KNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLR 3645
K LK+LED +LR L +TG++LD+V LV+TL +K ATEV+E+L+ +E T ++ D R
Sbjct: 3545 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR 3604
Query: 3646 DGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMD 3705
+ YRP A+R +ILFFVL++M ++ MYQ+SL A++ +F LS+ KS + L R+ + D
Sbjct: 3605 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND 3664
Query: 3706 TLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEK-SKRKK 3764
T+++Y + C LFERHKLLFSF+M KI + G++ +E +FFL+G + L++ +
Sbjct: 3665 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN 3724
Query: 3765 PC-AWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823
PC +WL+D W++I L ++ NF L + E W WY + E+ +P ++N
Sbjct: 3725 PCSSWLADAYWDNITELDKL--TNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENA 3782
Query: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883
Q++LI+R R DRV VT ++ +G ++++PP+++ +++ E STP SP+VFILS
Sbjct: 3783 CNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILS 3842
Query: 3884 PGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVK 3943
PG DP + L++LAE G R L++GQGQ +A +LL V +G W+ L NCHL +
Sbjct: 3843 PGVDPTSALLQLAEHMGM-AQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLS 3901
Query: 3944 WLKDLEKSLE--RITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATY 4001
W+ +L+K +E ++ PHP FRLWL++ P FPI ILQ S+K+ TEPP GLK NM Y
Sbjct: 3902 WMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLY 3961
Query: 4002 FKISHEMLDQCPHPA-FKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEIL 4060
+S +C PA +K L++ L FFH+V+ ER+KF ++GWN+ Y FN+SDF+V +L
Sbjct: 3962 QLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLL 4021
Query: 4061 NTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQP 4120
+ YL + PW +LKYLI + YGG D +DRR+LT Y+++Y D T P
Sbjct: 4022 SLYLDEY-----EETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLST--P 4074
Query: 4121 FHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHL 4180
FH E Y IP + E I LP + PE FG HPNA++ A+ ++ L
Sbjct: 4075 FHRLSALET-YFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTL 4133
Query: 4181 LELQPQ-TGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQEL 4239
L LQPQ T + G +R++ + ++A +++ K+P++ D + +K L SP +VVLLQE+
Sbjct: 4134 LSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEI 4193
Query: 4240 ERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGN 4299
+R+N L+ + SL +L++ + G + MS L+++ +F H+P +W + P + K L
Sbjct: 4194 QRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYP-SQKPLAA 4252
Query: 4300 WMVYFLRRFSQYMLWVTESEPSVM-WLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQ 4358
W R Q+ LW + + P V+ WLSG P +LTA++Q++ R+N +D +
Sbjct: 4253 WTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFI 4312
Query: 4359 VTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAH 4418
V+ D++ V G +V GLYLEGA WD + CL++++P LV +P + P E+
Sbjct: 4313 VSTVDDSNLVYP-PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESR 4371
Query: 4419 RLKLQNTFRTPVY-----TTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTLNSD 4471
+ + + P Y S R + +G+ + T HW+ +G L ++ D
Sbjct: 4372 KKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTP---DHWIKRGTALLMSLD 4426
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 2323 bits (6020), Expect = 0.0
Identities = 1450/4563 (31%), Positives = 2407/4563 (52%), Gaps = 292/4563 (6%)
Query: 100 VFFLRNTKE-AISEATDMKEAMEIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHR 158
+FF+R + AI+ T +EA+ + + + G++N +++++ +FLPA+ +
Sbjct: 19 IFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNG-----IRDMLANIFLPAVLATNNW 72
Query: 159 TSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQL 218
G ++ S + ES+ + F + ++ S + +
Sbjct: 73 ---------GALNQSKQGESE-----------------KHIFTETINRYLSFLDGARISI 106
Query: 219 EGEIKLE------MPIISVEGEVSDLAADPETVDILEQCVINWLNQISTAV--EAQLKKT 270
EG +KL+ + EV+ A++ ETV LE+ ++ W QI + Q++K
Sbjct: 107 EGTVKLKTIDNVNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQIEQVLIESEQMRKE 166
Query: 271 PQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKF 330
GPL E+E W+ +A + + EQ K P + V++V+ + S L+ N + + +
Sbjct: 167 AGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDT 226
Query: 331 HTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPL 390
E+ DNVR+L T+E+ + + + + I +++A+RM+ +SR+YN ERM L
Sbjct: 227 ANESKDNVRYLYTLEKVCQPL-YNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSL 285
Query: 391 MERIAWEIAERVCRVV----NLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEA 446
++ ++ C+ L ++ + K + + ++ ++ TR I
Sbjct: 286 FIKVTNQMVT-ACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQASFHKTRKLISE 344
Query: 447 SGREDRWEFDRKRLF----------ERTDYMATICQDLS----------DVLQILEEFYN 486
S E +E +F E+ M T+ Q S D++ I +F N
Sbjct: 345 SSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI--KFRN 402
Query: 487 IFGPELKAVTG--DPKRID------DVLCRVDGLVTPMENLTFDPFS-IKSSQFWKYVMD 537
I+ K DP+R + D + +++GL ++ F I SSQ ++
Sbjct: 403 IYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQ 462
Query: 538 EFK--------------IEVLI-------DIINKIFVQNLENPPLYKNHPPVAGAIYWER 576
F+ IE ++ D K++ ++PPL +N PP+AG I W R
Sbjct: 463 RFQKLNIPCLGLEINHTIERILQYYVAELDATKKLYHSQKDDPPLARNMPPIAGKILWVR 522
Query: 577 SLFFRIKHTILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPA 636
L+ RI I F + +IL S G+ V ++Y ++ + E+E + W+ Q+ A
Sbjct: 523 QLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQLHYA 582
Query: 637 LMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVAL 696
L ++++ P T +NF P + E++ ETK + ++ VPE A+ +
Sbjct: 583 L-------QATLFVRHPET----GKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLK 631
Query: 697 QEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIG 756
E K +Q +L +Y L + L+ +++ V R G L W+SL +
Sbjct: 632 LESKLKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLE 691
Query: 757 DYITGCKQAIGKFESLVHQI----HKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKE 812
+ + + F L+ +I + D + + I+L + A K E+ L +
Sbjct: 692 SFFQEVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNET 751
Query: 813 FFEH---IERERASDVDHMVRWYLAIGPLLTKVE-------------GLVVHTNTGKAPK 856
+ + I ++ V+ VR ++I + +V+ +V + TG+
Sbjct: 752 YTKEWADILNHKSKHVEEAVRELISIFEQIYEVKYTGKVGKQSEQRKHVVFGSETGEGEN 811
Query: 857 ---------------LASYYKYWEKKIYEVLTKLILKNLQSFNSLILGN----------- 890
+K K+++ + +L +LQ L L
Sbjct: 812 NDYEANIVNEFDTHDKEDEFKKECKEVFAFFSHQLLDSLQKATRLSLDTMKRRIFVASLY 871
Query: 891 --------VPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNG---- 938
+ +E L P +++ P+ ++I + ++ +E+++ W
Sbjct: 872 GRKQSEDIISFIKSEVHLAIPNVVMIPSLDDIQQAINRMIQLTLEVSRGVAHWGQQQIRP 931
Query: 939 --SCIECPPQ------------KGEE---EEVV----IINFYNDISLNPQIIEQAVMIPQ 977
S I P K EE EE + + NFY ++ + I + +++
Sbjct: 932 IKSVIPSPTTTDVTHQNTGKLLKKEERSFEEAIPARKLKNFYPGVAEHKDISKLVLLLSS 991
Query: 978 NVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMR 1037
+V+ + + LQ +++Y+ LW D+ + +++F A P ++ Y+ E+
Sbjct: 992 SVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIDE 1051
Query: 1038 HPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRK 1097
I + L + + AK+W + L + LNE K+++ + + K L +
Sbjct: 1052 LKPIIVVGALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEYLKKLSR 1111
Query: 1098 IPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESI 1157
L+D++F + ++ IR + M++ ++E Y + + + E E VD +
Sbjct: 1112 PIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYS 1171
Query: 1158 WSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGV 1217
++ L + +V+V+ L ++ F + +R + FA+ + EGP +
Sbjct: 1172 FNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 1218 ELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVA 1277
L +++ + ++ E+LF LP+T Y L K +KE++ L+ +Y LY+ + +
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 1278 KEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLD 1337
+ + LW +++++ + + F RKLP+ ++ L+ ++ F +S PLL
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1338 LKNEALRDRHWKELMEKTSVFFEM-TETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIE 1396
+ N+A++ RHW + E T F++ +++F L N+ L KH D + +I +AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1397 KAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPF 1456
+ ++++ W N + + KG E EII ++D+ L S+ +R+ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAF-KGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1457 LQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKR 1516
+ + W LS ++IE W++VQ W+YLE++F+GGDI QLP+EAK+F NIDK + +
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1517 IMGETLKDPVIKRCCEAPNRLSDL-QNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDE 1575
IM ++P + CC + L ++ E LE CQKSL YL+ KR FPRFFF+SD
Sbjct: 1531 IMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPV 1590
Query: 1576 LLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAE 1634
LL ILG +SD +Q H+ + DNI + F+ D + A+IS EGE + + A+
Sbjct: 1591 LLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDR--IMAVISREGEKIVLDNSVMAK 1648
Query: 1635 GRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRV-DWMLLYQGMVVLAASQVWWTWEV 1693
G VE W+ +L + I + A ++ + ++ ++ + V L Q+ WT +
Sbjct: 1649 GPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDS 1708
Query: 1694 EDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVD 1753
E+ A K +++ M+ +K ++ L+++ T LSK DR K+ T++ I VH RDI D
Sbjct: 1709 EEALRNA-KDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIHVHQRDIFD 1767
Query: 1754 SFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDR 1813
++ I +F+W Q RFY+ + D+ + F Y E++G RLVITPLTDR
Sbjct: 1768 DLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDR 1827
Query: 1814 IYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSG 1873
Y+TL QAL M +GGAPAGPAGTGKTETTKD+ + LG VV NC + MD+R +G+IF G
Sbjct: 1828 CYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKG 1887
Query: 1874 LAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQF-EGQEISLDSRMGIFI 1932
LAQ G+WGCFDEFNRI+ VLSV + QI + A + F F +G + L+ GIF+
Sbjct: 1888 LAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFL 1947
Query: 1933 TMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLA 1992
TMNPGYAGR ELPE++K FR V ++VPD Q I + L S GFLE LA+K VLYKL
Sbjct: 1948 TMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLC 2007
Query: 1993 REQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLF 2052
EQL+KQ HYDFGLR + SVL G KR + E ++MR LRDMNL K V ED PLF
Sbjct: 2008 EEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLF 2067
Query: 2053 LGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVV 2112
L LI+DLFPGL Y + +AV ++ G P K+VQ++ET L RH M +
Sbjct: 2068 LSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTL 2127
Query: 2113 GPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIF 2172
GP+ GK+ VI L +AQT+ G + +NPKA++ +++G LD T DWTDG+ S ++
Sbjct: 2128 GPSGSGKTTVITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLW 2187
Query: 2173 REINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVG 2232
R+ K K E +++ DG VDA+W+EN+NSV+DDN+ LTLANG+RI + C LLFEV
Sbjct: 2188 RKTLK-AKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVH 2246
Query: 2233 DLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVI 2292
+++ ASPATVSR GMVY+ L +RP + W+ + + L +L+EK
Sbjct: 2247 NIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTAQEAAVFL-TLYEK--------- 2296
Query: 2293 VEGIVDGRQAEKLKTIVPQTDL---NMVTQLAKMLDALL----EGEIEDLDLLECYFLEA 2345
+ + + P+ L N + Q +L+ L+ EG + ++ L F+
Sbjct: 2297 ---VFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHKLFVFG 2353
Query: 2346 LYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELP-GQLPTLYDFHFDNKRN 2404
L SLGA L + R K + ++++ S + E+P G T+Y+F+ +
Sbjct: 2354 LMWSLGALLELESREKLEAFLRQHESKLDLP---------EIPKGSNQTMYEFYVTDY-G 2403
Query: 2405 QWVPWSKLVPEYIHAPER--KFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKT 2462
W W+K + Y + + ++ +ILV VD RT ++++ + K + V+ GE GT+KT
Sbjct: 2404 DWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKT 2463
Query: 2463 ATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMD 2522
+ +LK E + +NFSS T M QR +E+ V+KR TYGPP G+++ VF+D
Sbjct: 2464 VMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFID 2523
Query: 2523 DMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVD 2582
D+NMP ++E+G Q +++ ++E +Y K + +I D+ IAAM GGGRN++
Sbjct: 2524 DINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIP 2583
Query: 2583 PRFISLFSVFNVPFPSEESLHLIYSSILKGHTS---TFHESIVAVSGKLTFCTLALYKNI 2639
R F+VFN PS S+ I+ I G+ +F I + L L++
Sbjct: 2584 QRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWT 2643
Query: 2640 VQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISE 2699
+ PTPSKFHYIFNLRDLSR++ G++ E ++ ++ ++++EC RV DR I+
Sbjct: 2644 KVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITP 2703
Query: 2700 TDKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGE-----------PRIYED 2748
D+Q H+ V E+ D + F DF + E P+IYE
Sbjct: 2704 EDEQWFNAHLTRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYEL 2763
Query: 2749 IQDYEAAKALFQEILEEYNE--SNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGG 2806
+ ++ Q ++NE T ++LV F DA+ HL ++ RIIR G+ALLVGVGG
Sbjct: 2764 MPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGG 2823
Query: 2807 SGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVA 2866
SGKQSLSRLA+F A ++F+I L+R Y+ + +DLK+LY G + K + F+FTD+ +
Sbjct: 2824 SGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIK 2883
Query: 2867 EEGFLELINNMLTSGIVPALFSEEEKESI----LSQIGQEALKQGMGPAKESVWQYFVNK 2922
+E FLE +NN+L+SG + LF+ +E + I +S + +E + P +++++YF+++
Sbjct: 2884 DEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHP--PTFDNLYEYFISR 2941
Query: 2923 SANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLG-YNPMI 2981
S NLH+VL SPVG+ R FPG+++ +DWF WP +AL AVA FL YN +
Sbjct: 2942 SRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVC 3001
Query: 2982 PAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNI 3041
+E VV+ + L H V + + Q+ RR +VTPK+YL FIN Y + EK +
Sbjct: 3002 SSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFIN 3061
Query: 3042 AQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKK 3101
Q +R++ GLDKL EA+ + +L+Q LA ++ LA S + +L E+ V+ + + K
Sbjct: 3062 EQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKN 3121
Query: 3102 LAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPK 3161
+E + ++ I EK +AE+ L P LE A+ L + +D+ +R AKPP
Sbjct: 3122 EVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPH 3181
Query: 3162 QVQTVCECILIM-------------KGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQS 3208
+ + +C+L++ K + +W + +MS FL SL + D+I +
Sbjct: 3182 LIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEE 3241
Query: 3209 QVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNF 3268
V+ ++ + T E + V G+L + A+ + + RE+ P + +A+ E
Sbjct: 3242 TVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRL 3301
Query: 3269 YLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLG 3328
+ EL + Q L Q EL+ + AK++AA+ EK L +A+ +++ AA LI GL
Sbjct: 3302 AVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLS 3361
Query: 3329 SENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIP 3388
E IRW E + +L+GD LLC FLSY G F FR+ ++ W+ ++ R+IP
Sbjct: 3362 GEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIP 3421
Query: 3389 LSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKR 3448
++ L S+L D I WG QGLP D+LS+QNGI+ T+A+R+PL IDPQ Q WIK
Sbjct: 3422 FTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKS 3481
Query: 3449 KEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQF 3508
KE++N+L+V S N F LE S+ G P L D+ E +DP +DNVLEKN + G F
Sbjct: 3482 KEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTF 3540
Query: 3509 -IILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYE 3567
+ +GDKE D F+LY+ TKL NP ++P + K VI++TVT+KGLE+QLL ++ E
Sbjct: 3541 KVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTE 3600
Query: 3568 RRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEV 3627
++ELE +R L+++ + NK +K+LED+LL +L+ + G+++D+ L+ L TK A EV
Sbjct: 3601 KQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEV 3660
Query: 3628 SEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSL 3687
SEKL +A +T + I+ ++ +RPAA RG+IL+F+++EM++VN MYQ SL FL++F S+
Sbjct: 3661 SEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSM 3720
Query: 3688 KKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEEL 3747
+S + KR+ NI++ LT+ ++ + GL+E HK LF MT+KI+ G V E
Sbjct: 3721 ARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREF 3780
Query: 3748 DFFLKGNISLE-KSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWY 3806
+KG +L+ K+ KP W+ D W +++ LS++ F ++ + + N+ W+ W+
Sbjct: 3781 QALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKL--PQFAEIMNQISRNEKGWKSWF 3838
Query: 3807 DLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFE 3866
D D+ E+ +P GY++++ KLL++R + DR Y+ ++ EKY +P +++ E
Sbjct: 3839 DKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLE 3898
Query: 3867 AIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETA 3926
+E+S +P++ LS GSDP + LA++ + ++MGQGQE A +L++ +
Sbjct: 3899 KTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMS 3955
Query: 3927 VARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVV 3986
+ +G W++LQNCHL ++++++L ++L FR+W+TT+P FPI +LQ SLK
Sbjct: 3956 MQQGGWVLLQNCHLGLEFMEELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFT 4015
Query: 3987 TEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046
EPP G++ ++ T+ I+ ++LD P +KP++Y +AF H+ VQERRKFG +GWN+ Y
Sbjct: 4016 NEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPY 4075
Query: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106
+FN +DF ++ + +L + ++ + W +++Y+IGEV YGGR D FD+R+L +
Sbjct: 4076 EFNSADFSASVQFIQNHLDECDIKKG--VSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFA 4133
Query: 4107 DEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEI 4166
+ + +F+ F+ YKIP+ +++ E I++LP + PEVFGLHPNA+I
Sbjct: 4134 RVWFSEKMFEPSFCFY------TGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADI 4187
Query: 4167 GYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRL-- 4224
Y + A + + +QP+ G +R+ + ++++++ +K+P + +V+ RL
Sbjct: 4188 TYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIK 4247
Query: 4225 GTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPN 4284
L+ ++ L QE++R +++ + SL++L+ A+ G + MS L D +++ IP
Sbjct: 4248 MGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQ 4307
Query: 4285 IWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCR 4344
+W+R++ D+ +LG W L R +Q+ W+ E P+V W++G P+ +LTA+ Q R
Sbjct: 4308 LWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTR 4366
Query: 4345 KN-GWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVL 4403
+ GW LD T+ +V + Q +E+ G+G ++ GLY++GA WD G L++S PKVL
Sbjct: 4367 AHKGWALDTVTIHNEVLR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVL 4425
Query: 4404 VVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQG 4463
LP+L I I + K + P+Y R + + +V+ L T HW+L+G
Sbjct: 4426 FTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRG 4482
Query: 4464 VCL 4466
V L
Sbjct: 4483 VAL 4485
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 2314 bits (5997), Expect = 0.0
Identities = 1448/4447 (32%), Positives = 2374/4447 (53%), Gaps = 262/4447 (5%)
Query: 180 LPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLA 239
LP + E + +I ++ + ++ ++Q++G+ L +P S + E +D
Sbjct: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
Query: 240 A-------DPETVDILEQCVINWLNQISTAVEAQLKKTP-QGKGPL--AEIEFWRERNAT 289
+ D + +E VI W Q+ ++ + + QG+ P E+EFW+ R
Sbjct: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
Query: 290 LSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFK 349
L ++ Q + VR + ++ + S + ++ ++ EA D L ++R+ +
Sbjct: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
Query: 350 NITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLR 409
+ + F V + ++ + ++W + Y R+ L++ I + ++ ++
Sbjct: 322 ALENAE-FPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPE 380
Query: 410 TLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEASGREDR----WEFDRKRLFERTD 465
L + +Q K +TL +K+ + D R + +E++ W+F +F R D
Sbjct: 381 DLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVRLD 440
Query: 466 YMATICQDLSDVLQILEEFYNIFGPELKAVTGD--PKRIDDVLCRVDGLVTPMENLTFDP 523
+ +L+ +F+ + E V G+ +++ + + + + D
Sbjct: 441 GFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDC 500
Query: 524 FSIKSSQFWKYVMD-EFKIEVLIDIINKIFVQNLENPPLYKNH---PPVAGAIYWERSLF 579
++S+ F V + K+E L + IF+Q ++ P ++ +AG + ER L
Sbjct: 501 LYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLL-ERPLV 559
Query: 580 FR---IKHTILRFQEVQEILDSDR-------------------------------GQEVK 605
R K+ +L Q + LD+ R QE++
Sbjct: 560 ARDTSDKYLVL-IQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618
Query: 606 QKY-----------------LEVGRTMKEYED----------RKYEQWMEVTEQVLPALM 638
Q+ E R ++YED R YE W + +
Sbjct: 619 QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678
Query: 639 KKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFT-VPELARNVALQ 697
+ LL + +P T E INF+P L ++ E YLE +PE A +
Sbjct: 679 SQPLLKR------DPETKE----ITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSS 728
Query: 698 EDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGD 757
D + + A ++ M + Y+ ++ TL + E L+++ Q + R+ + LNW + GI D
Sbjct: 729 RDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICD 788
Query: 758 YITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHI 817
Y+T +I E + + N ++I + + + P K+++ G +E +
Sbjct: 789 YVTEITSSIHDLEQRIQKTKDNVEEIQN------IMKTWVTPIFKTKD---GKRESLLSL 839
Query: 818 ERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTG--KAPKLASYYKYWEKKIYEVL--- 872
+ D M ++Y I K+ L V N G A ++ +K + I +L
Sbjct: 840 DDRH----DRMEKYYNLIKESGLKIHAL-VQENLGLFSADPTSNIWKTYVNSIDNLLLNG 894
Query: 873 ----TKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEI 928
+ LK L G P+F + L PE++ +P+ K F C + VE
Sbjct: 895 FFLAIECSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGF-C--DIVEG 951
Query: 929 TKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK 988
+ + PQ G ++ D+ P + + + V R++
Sbjct: 952 LITSIFRIPSLVPRLSPQNGSP------HYQVDLDGIPDLANMRRTLMERVQRMMGLCCG 1005
Query: 989 YLQKWKRYRPLWKLDKAIVMEKF-------------------AAKKPPCVA-YDEKLQFY 1028
Y + +Y L+ D+ V+ +F + PP ++ + ++ Y
Sbjct: 1006 YQSTFSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSY 1065
Query: 1029 SKIAYEVMR-HPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEE 1087
+ EV R P+ + +++ +R ++ K W + + L + L NL
Sbjct: 1066 ETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAF 1125
Query: 1088 MEHLAKNLRK--IPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPD 1145
++ L K + L ++ + ++ + + + +++ + Y P+
Sbjct: 1126 IKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPE 1185
Query: 1146 AEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG 1205
+ ++++ W+N+ ++ V+ + ++ L R + + ++F ++F+ E
Sbjct: 1186 TVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEA 1245
Query: 1206 PGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLR 1265
P D ++L E+ + E + ++ + LF++ + Y +L + +KE+ L+
Sbjct: 1246 PFRF--DSIHPHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLK 1303
Query: 1266 MIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKM 1325
+++ + + W T W N+NV+ ++ + F R +R L + VR LE+ +
Sbjct: 1304 ELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTV 1363
Query: 1326 KAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEI 1385
S+ + +L+N A+R+RHW++LM+ T V F M + TL ++ ++LH + D + I
Sbjct: 1364 WNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGI 1423
Query: 1386 VTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQ 1445
V A KE+ +EK +KE+ TW M+F +Y + +L S +++I+ L+DN LQ
Sbjct: 1424 VDKAAKEMGMEKTLKELQTTWAGMEF---QYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQ 1480
Query: 1446 SISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEA 1504
++ S++V FL+ V W+K LS + VI IW VQR W +LESIF G DIR+QLP+++
Sbjct: 1481 NLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDS 1540
Query: 1505 KKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNA 1564
K+F+ ID FK + + K P + + P L+++ L C+K+L +YLD+KR A
Sbjct: 1541 KRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLA 1600
Query: 1565 FPRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRFNDGDSGE--KLVSAMISAE 1621
FPRF+F+S +LL IL + + P VQ H+ K++DN+A +RF SGE K M S E
Sbjct: 1601 FPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKE 1660
Query: 1622 GEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVV 1681
E + F + G+VE W+ VL M+ T R E + Y E++ R W+ + V
Sbjct: 1661 EEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAY-EEKPREQWLFDHPAQVA 1719
Query: 1682 LAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTV 1741
L +Q+WWT EV F + ++G + AMK+Y +K Q+ L+T + LSK DR+K T+
Sbjct: 1720 LTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTI 1779
Query: 1742 LIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGL 1801
IDVHARD+V I + A+ F W SQLR WD E C F Y YEY+G
Sbjct: 1780 CTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGN 1839
Query: 1802 NGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEG 1861
RLVITPLTDR Y+TLTQ+L + + GAPAGPAGTGKTETTKDL +ALG+L V NC E
Sbjct: 1840 TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQ 1899
Query: 1862 MDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQE 1921
MDY++ G I+ GLAQ GAWGCFDEFNRI VLSV++ Q+++I++A+ + F F G+E
Sbjct: 1900 MDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEE 1959
Query: 1922 ISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTL 1981
ISL+ +GIFITMNPGYAGRTELPE++K+LFRP ++VPD + ICEIML +EGF+EA++L
Sbjct: 1960 ISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSL 2019
Query: 1982 AKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNL 2041
A+K LY+L +E LSKQ HYD+GLRA+KSVLV+AG LKRG D ED VLMR+LRD N+
Sbjct: 2020 ARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNI 2079
Query: 2042 PKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFE 2101
PK V +D+P+F+GLI DLFP LD PR R P+F V + + + V KVVQ+ E
Sbjct: 2080 PKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEE 2139
Query: 2102 TMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTR 2161
+ RH+ VVG GKS V+ +L + + LNPKAV+ EL+GI++P T
Sbjct: 2140 LLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATG 2199
Query: 2162 DWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRL 2221
+W DG+ S+I RE+ T K+IL DGD+D +W+E++N+VMDDN++LTLA+ ERI L
Sbjct: 2200 EWKDGLFSSIMRELANITHDGP-KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPL 2258
Query: 2222 QAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLF 2281
LLFE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+ NL LF
Sbjct: 2259 NPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILF 2318
Query: 2282 EKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----L 2337
+KY+P +D + + K I+P + +MV + +L+ LL E D +
Sbjct: 2319 DKYLPTCLDTL---------RTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEI 2369
Query: 2338 LECYFLEALYCSLGASLLEDGRMKFDEYIKR--LASLSTVDTEGVWANPGELPGQLPTLY 2395
E YF+ A + G ++++D + + + L TV + P Q T++
Sbjct: 2370 YEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTV----------KFPSQ-GTIF 2418
Query: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
D++ D + ++ PWSKLVP++ PE LVHT +T R + +E+++ ++PV+ VG
Sbjct: 2419 DYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVG 2478
Query: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
+GT K+ L +L E +V V F+ TTS +Q LE +EK+ YGPP K
Sbjct: 2479 TAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNK 2538
Query: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
+L+ F+DDMNMP VD YGT QP +++ L+ G+ YDR K L+ K I ++ +++ M
Sbjct: 2539 KLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSK-LSLKEITNVQYVSCMNPTA 2597
Query: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTL 2633
G ++PR FSVF + FP ++L IYS IL H F S+ L L
Sbjct: 2598 GSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLAL 2656
Query: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693
A ++ I PT KFHYIFNLRD + +F G++ ++ E ++ ++R++ +E RV+
Sbjct: 2657 AFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYR 2716
Query: 2694 DRLISETDKQL---VQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQ 2750
D+++ E D L +Q + + +D VE + P L+ F + GEP+ Y +Q
Sbjct: 2717 DKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQT-QSPNLYCHFANGI--GEPK-YMPVQ 2772
Query: 2751 DYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQ 2810
+E E LE +NE NT M+LVLF+DA+ H+ ++RI+ RG+ALLVGVGGSGKQ
Sbjct: 2773 SWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQ 2832
Query: 2811 SLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGF 2870
SL+RLAAF +S +VF+I L +GY F+ DL SL LK G++N +FL TDA VA+E F
Sbjct: 2833 SLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERF 2892
Query: 2871 LELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIV 2930
L LIN++L SG +P L+S++E E+I+S + E QG+ +E+ W++F+++ L +
Sbjct: 2893 LVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVT 2952
Query: 2931 LGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVV 2990
L SPVG+ LR R FP +VN T I WF WP QAL +V+ FL I +++
Sbjct: 2953 LCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSIS 3012
Query: 2991 KHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGG 3050
K + VH SV+ SQ +L +R NY TPK++L+FI Y LL + + +RL+ G
Sbjct: 3013 KFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENG 3072
Query: 3051 LDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
L KL + Q+D+L KLA Q++ L +K+ + L++ + V T K++ EKAM
Sbjct: 3073 LLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVET------DKVSREKAMAD 3126
Query: 3111 EEQNKV------IAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
EE+ KV + ++ + E LA+ P L AA+ L L+K+++TE++SF PP V
Sbjct: 3127 EEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVS 3186
Query: 3165 TVCECILIM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLK 3218
V ++++ + K+ +WK AK M+ FL SL+ + ++I ++ +K I+ L+
Sbjct: 3187 NVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQ 3246
Query: 3219 TLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERI 3278
E + S A G+ +V ++ + +VF +++PKR+ + + + + +L I
Sbjct: 3247 DPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAI 3306
Query: 3279 QNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDL 3338
+ ++A + + L L A++E A +K K Q+EAE+ + A++L+ GL SEN+RW + +
Sbjct: 3307 KAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAV 3366
Query: 3339 DELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLE 3396
+ L GD LL AF+SY G FT ++R +++R W+ + L+ IP++
Sbjct: 3367 QNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPL 3426
Query: 3397 SLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLR 3456
+L DD +++ W ++GLP D +SV+N + R+PL +DPQ Q + WIK K + +LR
Sbjct: 3427 RMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGE-DLR 3485
Query: 3457 VASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEV 3516
V +L+ +E +++ G L +++E IDPV+ +L + + + +GR FI +GDKE
Sbjct: 3486 VTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREV-IKKGR-FIKIGDKEC 3543
Query: 3517 DYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQRE 3576
+Y+ FRL L+TKLANP Y P + +A +IN+TVT GLEDQLL+ +V+ ER +LE+ +
Sbjct: 3544 EYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKS 3603
Query: 3577 HLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEK 3636
L ++ + K LK LEDSLL L++++GN L LV LE TK A EV +K++ A+
Sbjct: 3604 DLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKV 3663
Query: 3637 TALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSIL 3696
T + I+ R+ YRPAA R ++L+F++++++ ++ MYQ+SL AF VF+ +++++ PD L
Sbjct: 3664 TEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESL 3723
Query: 3697 MKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNIS 3756
+R+ N++D++TFS+Y + GLFE KL + +T +I V ELDF L+ +
Sbjct: 3724 RERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV- 3782
Query: 3757 LEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPV 3816
++ P +LS Q W + +LS M + F L D+E + W+++ + + E+ +
Sbjct: 3783 --QTGTASPVEFLSHQAWGAVKVLSSM--EEFSNLDRDIEGSAKSWKKFVESECPEKEKL 3838
Query: 3817 PLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHS 3876
P + N T Q+L +LR R DR+ A+ D+V +G KYV + F FE+S P +
Sbjct: 3839 PQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPAT 3897
Query: 3877 PIVFILSPGSDPATDLMKLAERSGFGGNRLKF--LAMGQGQEKVALQLLETAVARGQWLM 3934
P+ FILSPG DP D+ + G+ N F +++GQGQE VA L+ A +G W++
Sbjct: 3898 PMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVI 3957
Query: 3935 LQNCHLLVKWLKDLEKSLERITK-PHPDFRLWLTTDPTKG-----FPIGILQKSLKVVTE 3988
LQN HL+ KWL LEK LE ++ HP+FR++++ +P P GIL+ S+K+ E
Sbjct: 3958 LQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNE 4017
Query: 3989 PPNGLKLNMRATYFKISHEMLDQCPHPA-FKPLVYVLAFFHAVVQERRKFGKIGWNVYYD 4047
PP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 4018 PPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
Query: 4048 FNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMD 4107
FN D + + +L +L + + ++P+ L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4078 FNTGDLTISVNVLYNFL-----EANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLG 4132
Query: 4108 EYLGDFIFD---TFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNA 4164
E++ + + + P + +P + + + I+A +P ++GLHPNA
Sbjct: 4133 EFIRPEMLEGELSLAP---------GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
Query: 4165 EIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQVAKEIENKMPKVFDLDQVRK 4222
EIG+ TQ + ++ +LELQP+ ++ +G +R++ + + +EI ++ F++ ++
Sbjct: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA 4243
Query: 4223 RLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHI 4282
++ +P VV QE R N L + +SL EL+ L GE+ M++ ++++ +L+ +
Sbjct: 4244 KV-EERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMV 4302
Query: 4283 PNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTE-SEPSVMWLSGLHIPESYLTALVQA 4341
P W R A + L W L R + W + + PS +WL+G P+S+LTA++Q+
Sbjct: 4303 PESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4362
Query: 4342 TCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPK 4401
T RKN WPLD+ L +TK ++ +E +G ++ GL++EGA WD + G + ++K K
Sbjct: 4363 TARKNEWPLDQMALQCDMTK-KNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLK 4421
Query: 4402 VLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHISHWVL 4461
L +P++ I I A + ++ + PVY TS R G V+ +L T + S WVL
Sbjct: 4422 DLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GPTYVWTFNLKTKENPSKWVL 4477
Query: 4462 QGVCLTL 4468
GV L L
Sbjct: 4478 AGVALLL 4484
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 2290 bits (5935), Expect = 0.0
Identities = 1431/4451 (32%), Positives = 2361/4451 (53%), Gaps = 290/4451 (6%)
Query: 194 QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248
Q++ ++ + V + + + +++G+ L +P + S++G + + P ++D L
Sbjct: 132 QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191
Query: 249 --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303
E +I+W +QI + AQ P E EFW R L +HEQ P V
Sbjct: 192 AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVN 251
Query: 304 KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363
K++++++++ S LQ V+T + + EA+D V +L + + + + F ++
Sbjct: 252 KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ-ADFTMLPTF 310
Query: 364 IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423
I ++ + +W S +YN R+I +++ +I E ++ + K + +
Sbjct: 311 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370
Query: 424 LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477
+ + K+ Y +D K+ +E WEF F R + Q + ++
Sbjct: 371 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430
Query: 478 LQILEEFYNIFGPELKAVTGD--PKRIDDVLCRVDGLVTPMENLTFDPF----------- 524
+ EF + EL V G+ + + V LV + +DP
Sbjct: 431 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSVGPRAG 490
Query: 525 --SIKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWERSLFFR- 581
+ S+ Y E KI+ L + IF Q ++ K+ A +Y L R
Sbjct: 491 LDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSS---AKLLYMCGGLMERP 547
Query: 582 --IKHTILRFQEVQEILDSD------------------------------RGQ------- 602
+ R+ + E+ D++ GQ
Sbjct: 548 LILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLEL 607
Query: 603 ----EVKQKYL-----------EVGRTMKEYE----------DRKYEQWMEVTEQVLPAL 637
EV K+L E T ++Y+ ++ Y+QW+ +Q
Sbjct: 608 QERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFN 667
Query: 638 MKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVAL 696
+ + L+ + + + + +NFS AL ++ E KYL Q +P+ A ++
Sbjct: 668 LGQPLILRDAASN----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFS 717
Query: 697 QEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIG 756
+ + F ++ ++ ++ Y+ + + E +L+K + + S L WN G+
Sbjct: 718 ENETFRKFVGNLELIVGWYNEV---MKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVF 774
Query: 757 DYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEH 816
YI ++ + ++ + + +N + IS + A LF+ K E L
Sbjct: 775 QYIQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL--------- 825
Query: 817 IERERASDVDHMVRWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEV 871
+ + ++ + Y A+ K++ +V + +A L+ Y Y + + +
Sbjct: 826 ---DLDGRIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDE 882
Query: 872 LTKLILKNLQ-SFNSLILGN--VPLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCV 926
+ I K+L +++++ PLF L + +P T E+ D+ + V
Sbjct: 883 FDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLV 941
Query: 927 EITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINL 986
+ R + P+ ++ +N+ D+ N +IE + + V ++IN
Sbjct: 942 NDIYNVARLI--------PRLAKDR----MNYKMDLEDNTDLIE----MREEVSSLVINA 985
Query: 987 MK----YLQKWKRYRPLWKLDKAIVMEKF-------------------AAKKPPCVA-YD 1022
MK Y ++RY LW + M+ F K PP +A +
Sbjct: 986 MKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQ 1045
Query: 1023 EKLQFYSKIAYEVMRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEEL 1081
E++ Y K+ EV + K H ++ R + + W + L+ L
Sbjct: 1046 EQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSL 1105
Query: 1082 YNLHEEMEHLAKNLRK--IPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMY 1139
+L M+ L K + L V+ + +++ + + + +++ + Y
Sbjct: 1106 ADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTY 1165
Query: 1140 NLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAK 1199
P+ + ++ W+N ++ V+ + ++ + R + + ++ EF +
Sbjct: 1166 GEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRE 1225
Query: 1200 RFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQK 1259
RF E P S D + L ++ ++ E + L+ + LF++P+ Y +L +
Sbjct: 1226 RFRREAPFSFSD--PNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHR 1283
Query: 1260 EMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTY 1319
E+ L+ ++++ + + E+W T W ++NV+ + + F + +R L + ++
Sbjct: 1284 EVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFV 1343
Query: 1320 YLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHT 1379
L+ +K S+ + +L+N A+R+RHW++LM+ T V F+M+E TL ++ + LH +
Sbjct: 1344 GLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYE 1403
Query: 1380 DVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLD 1438
D + IV A+KE +EK +K + TW M+F + + GT +L S + ++++L+
Sbjct: 1404 DEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLE 1459
Query: 1439 DNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIR 1497
DN LQ++ S+++ FL+ V W++ LS VI IW VQR W +LESIFIG DIR
Sbjct: 1460 DNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIR 1519
Query: 1498 SQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDY 1557
+QLP ++++FD+I++ FK +M + +K P + P + L+ + + L C+K+L +Y
Sbjct: 1520 TQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEY 1579
Query: 1558 LDSKRNAFPRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLV 1614
L++KR AFPRF+F+S +LL IL + +DP+ V H+ K++D++ L+F + D K+
Sbjct: 1580 LETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVG 1639
Query: 1615 SAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWML 1674
M S E E M F + G+VE W+ VL+ M T R EA+ Y E++ R W+L
Sbjct: 1640 LGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWIL 1698
Query: 1675 LYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKND 1734
Y V L +Q+WWT EV F + ++G + A+++Y +K Q++ L+T + L+ D
Sbjct: 1699 DYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGD 1758
Query: 1735 RKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGY 1794
R K T+ IDVHARD+V I + ++ F W++QLR WD E C Y
Sbjct: 1759 RMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQY 1818
Query: 1795 GYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCV 1854
YEY+G RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG +
Sbjct: 1819 SYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVY 1878
Query: 1855 VTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTT 1914
V NC E MDY++ G I+ GLAQ GAWGCFDEFNRI VLSVI+ Q++ +++A+ +
Sbjct: 1879 VFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1938
Query: 1915 FQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEG 1974
F F G+ I L +GIFITMNPGYAGR ELPE++KALFRP ++VPD + ICEIML +EG
Sbjct: 1939 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEG 1998
Query: 1975 FLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMR 2034
FLEA+ LA+K LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG ED VLMR
Sbjct: 1999 FLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMR 2058
Query: 2035 ALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVD 2094
ALRD N+PK V +D+P+F+GLI DLFP LD PR R +F ++Q + E V
Sbjct: 2059 ALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVL 2118
Query: 2095 KVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 2154
KVVQ+ E + RH+ +VG GKS V+ +L + L L+PKAV+ EL+G
Sbjct: 2119 KVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFG 2178
Query: 2155 ILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLA 2214
I++P TR+W DG+ S I R++ T K+I+ DGD+D +W+E++N+VMDDN++LTLA
Sbjct: 2179 IINPVTREWKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLA 2237
Query: 2215 NGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQ 2274
+ ERI L L+FE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+
Sbjct: 2238 SNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEK 2297
Query: 2275 YNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIED 2334
NL LF+KY+P +D + G K I P ++ ++ + +L+ LL +
Sbjct: 2298 ANLMILFDKYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVP 2348
Query: 2335 LD----LLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---EL 2387
D L E YF+ + + G ++ +D + + V+ W N +
Sbjct: 2349 PDSPRELYELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKF 2397
Query: 2388 PGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKI 2447
P Q T++D++ D +++PW+ VP + P+ LVHT +T R + ++ +++
Sbjct: 2398 PSQ-GTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEK 2456
Query: 2448 KQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKD 2507
PV+ VG +GT K+ + L++L+ + +V V F+ TTS +Q LE +EK++
Sbjct: 2457 SWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGR 2516
Query: 2508 TYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGF 2567
YGPP K+L+ F+DDMNMP VD+YGT P L++ ++ + YDR K L K I + +
Sbjct: 2517 NYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQY 2575
Query: 2568 IAAMGKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVS 2625
+A M G +D R F VF V FP +E+L IY++IL H + + +I +S
Sbjct: 2576 VACMNPTSGSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRIS 2634
Query: 2626 GKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWR 2685
+L LAL++ I PT KFHY+FNLRDLS +F GL+ + E +T +VR+W
Sbjct: 2635 SQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWL 2694
Query: 2686 NECLRVFHDRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEP 2743
+E RV+ D+++ E D++ + + + + F DD+ E++ P +F F + G+P
Sbjct: 2695 HETERVYGDKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDP 2751
Query: 2744 RIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVG 2803
+ Y + D L ++L+ YNE N MNLVLF+DA+ H+ R++RI+ RG+ALLVG
Sbjct: 2752 K-YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVG 2810
Query: 2804 VGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDA 2863
VGGSGKQSLSRLAA+ + +VF+I L +GY + DL + Y+K ++N +FL TD+
Sbjct: 2811 VGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDS 2870
Query: 2864 HVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKS 2923
VAEE FL LIN++L SG +P LF E+E E+I+S + + GM +E+ W++F+ K
Sbjct: 2871 QVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKV 2930
Query: 2924 ANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPA 2983
L ++L SPVG LR R FP +VN T IDWF WP AL +V+ FL IP
Sbjct: 2931 RRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPV 2990
Query: 2984 ENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQ 3043
++ + VH +V+ S+ +L RR NY TPK +L+ I Y LL +K +A+
Sbjct: 2991 IK-ASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAK 3049
Query: 3044 CKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLA 3103
+RL+ GL KL+ Q+D+L KLA Q+ L +K+ + + L++ + + ++K +A
Sbjct: 3050 IERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIA 3109
Query: 3104 EEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQV 3163
+++ +++E NK + ++ ET LA+ P L AA+ L L+K+++TE++SF PP V
Sbjct: 3110 DQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAV 3169
Query: 3164 QTVCECILIM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLL 3217
V ++I+ K K+ +WK AK +M FL SL + D + I ++ +K K
Sbjct: 3170 VNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQ 3229
Query: 3218 KTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELER 3277
E + + S A G+ + ++ + +V+ ++ PKR+ + + +L R
Sbjct: 3230 GNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSR 3289
Query: 3278 IQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLND 3337
I+N++A + L L + +E A EK K Q+EA+ R ++ A++L+ GL SENIRW
Sbjct: 3290 IKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAES 3349
Query: 3338 LDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRL 3395
++ + V L GD LL +AF+SY G FT ++R+E++ + W I L+ IP++
Sbjct: 3350 VENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDP 3409
Query: 3396 ESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNL 3455
SLLTDD +++ W +QGLP D +S +N + R+PL +D Q Q + WIK K ++ L
Sbjct: 3410 LSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSEL 3468
Query: 3456 RVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKE 3515
+ +L +E +I G L ++ E +DPV+D +L +N + +G+ +I +GDKE
Sbjct: 3469 KAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKE 3526
Query: 3516 VDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQR 3575
V+Y FRL L+TK NP Y P + + +IN+ VT GLEDQLL+ +VA ER +LE+ +
Sbjct: 3527 VEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLK 3586
Query: 3576 EHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAE 3635
+L + +E K +LK+LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+
Sbjct: 3587 ANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAK 3646
Query: 3636 KTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSI 3695
T + I+ R+ YRPAA R ++L+F+L+++ +N +YQ+SL AF VF +++++ P +
Sbjct: 3647 ITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANE 3706
Query: 3696 LMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNI 3755
+ +R+ N+ D +T+S+Y + GLFER KL+F +T ++ + + ELDF L+
Sbjct: 3707 VKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF 3766
Query: 3756 SLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFP 3815
K+ P +L QGW I LSEM D F L D+E + W++ + ++ E+
Sbjct: 3767 ---KAGVVSPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEI 3821
Query: 3816 VPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPH 3875
P + N T QKL ++RC R DR+ A+ ++V MG K+V+ + F +E+S+P
Sbjct: 3822 FPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPS 3880
Query: 3876 SPIVFILSPGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWL 3933
+ I FILSPG DP D+ L ++ GF +L +++GQGQE VA L+ A +G W+
Sbjct: 3881 TSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWV 3940
Query: 3934 MLQNCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987
+LQN HL+ +WL L+K LER T H D+R++++ +P T P GIL+ ++K+
Sbjct: 3941 ILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 4000
Query: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046
EPP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 4001 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4060
Query: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106
FN D + + +L YL + +P++PW L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4061 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4115
Query: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
EY+ GD + ++IP + + + E I+ +P ++GL
Sbjct: 4116 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4163
Query: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQVAKEIENKMPKVFDLD 4218
HPNAEIG+ T + ++ +LE+QP+ +S +G+SR++ + V +I K+P+ F++
Sbjct: 4164 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMA 4223
Query: 4219 QVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLF 4278
++ + +P VV QE ER N L M +SL EL L GE+ ++ +++D++ +LF
Sbjct: 4224 EIMAK-AAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALF 4282
Query: 4279 IGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTE-SEPSVMWLSGLHIPESYLTA 4337
+P+ W A ++ L W L R + W T+ + P+ +WL+G P+S+LTA
Sbjct: 4283 YDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTA 4342
Query: 4338 LVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIK 4397
++Q+ RKN WPLD+ L +VTK ++ +++ +G +V GL++EGA WD + G + +
Sbjct: 4343 IMQSMARKNEWPLDKMCLSVEVTK-KNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAE 4401
Query: 4398 SKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHIS 4457
++ K L +P++ I I R++ +N + PVY T +R G V+ +L T +
Sbjct: 4402 ARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR----GPTYVWTFNLKTKEKAA 4457
Query: 4458 HWVLQGVCLTL 4468
W+L V L L
Sbjct: 4458 KWILAAVALLL 4468
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 2287 bits (5927), Expect = 0.0
Identities = 1445/4480 (32%), Positives = 2366/4480 (52%), Gaps = 333/4480 (7%)
Query: 194 QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248
Q++ ++ + V + + + +++G+ L +P + S++G + + P ++D L
Sbjct: 132 QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191
Query: 249 --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303
E +I+W +QI + AQ P E EFW R L +HEQ P V
Sbjct: 192 AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCIHEQLNRPKVN 251
Query: 304 KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363
K++++++++ S LQ V+T + + EA+D V +L + + + F ++
Sbjct: 252 KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQAD-FTMLPTF 310
Query: 364 IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423
I ++ + +W S +YN R+I +++ +I E ++ + K + +
Sbjct: 311 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370
Query: 424 LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477
+ + K+ Y +D K+ +E WEF F R + Q + ++
Sbjct: 371 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430
Query: 478 LQILEEFYNIFGPELKAVTGD------PKRIDDVL--------CRVDGLVTPMENLT--- 520
+ EF + EL V G+ + D+V C+ D L N
Sbjct: 431 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 490
Query: 521 ---------------------FDPFS-IKSSQFWKYVMDEFKIEVLI--------DIINK 550
FD S IKSS Y+ LI ++ +
Sbjct: 491 ADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEVAPRYSVMLE 550
Query: 551 IFVQNLEN-----------------PPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQ 593
+F L+N P ++KN PPVAG + W L R++ ++ + V+
Sbjct: 551 LFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVE 610
Query: 594 EILDSDRGQEVK---QKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIAT 650
+ S G E K QKY E+ ++ + ++ Y+QW+ +Q + + L+ + + +
Sbjct: 611 HPVMS--GAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLILRDAASN 668
Query: 651 EEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVALQEDKFLRYTAGIQ 709
+ +NFS AL ++ E KYL Q +P+ A ++ + + F ++ ++
Sbjct: 669 ----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLE 718
Query: 710 RMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKF 769
++ Y+ + + E +L+K + + S L WN G+ YI ++ +
Sbjct: 719 LIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNL 778
Query: 770 ESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMV 829
++ + + +N + IS + A LF+ K E L + + ++
Sbjct: 779 QNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL------------DLDGRIANLN 826
Query: 830 RWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEVLTKLILKNLQSF- 883
+ Y A+ K++ +V + +A L+ Y Y + + + + I K+L
Sbjct: 827 KRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLM 886
Query: 884 -NSLILGNV-PLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCVEITKHFVRWMNGS 939
N +I ++ PLF L + +P T E+ D+ + V + R +
Sbjct: 887 DNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLVNDIYNVARLI--- 942
Query: 940 CIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK----YLQKWKR 995
P+ ++ +N+ D+ N +IE + V ++IN MK Y ++R
Sbjct: 943 -----PRLAKDR----MNYKMDLEDNTDLIEMR----EEVSSLVINAMKEAEEYQDSFER 989
Query: 996 YRPLWKLDKAIVMEKFAA-------------------KKPPCVA-YDEKLQFYSKIAYEV 1035
Y LW + M+ F K PP +A + E++ Y K+ EV
Sbjct: 990 YSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEV 1049
Query: 1036 MRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKN 1094
+ K H ++ R + + W + L+ L +L M+
Sbjct: 1050 SKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMG 1109
Query: 1095 LRKI--PNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVD 1152
L K + L V+ + +++ + + + +++ + Y P+ +
Sbjct: 1110 LTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQ 1169
Query: 1153 KIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD- 1211
++ W+N ++ V+ + ++ + R + + ++ EF +RF E P S D
Sbjct: 1170 ELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDP 1229
Query: 1212 ----DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMI 1267
L+K L G+ E L+ + LF++P+ Y +L +E+ L+ +
Sbjct: 1230 NPYKSLNKVFLLKGIMEA-----------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
Query: 1268 YELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKA 1327
+++ + + E+W T W ++NV+ + + F + +R L + ++ L+ +K
Sbjct: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
Query: 1328 FKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVT 1387
S+ + +L+N A+R+RHW++LM+ T V F+M+E TL ++ + LH + D + IV
Sbjct: 1339 VITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVD 1398
Query: 1388 AAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLDDNTFNLQS 1446
A+KE +EK +K + TW M+F + + GT +L S + ++++L+DN LQ+
Sbjct: 1399 KAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLEDNQVQLQN 1454
Query: 1447 ISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAK 1505
+ S+++ FL+ V W++ LS VI IW VQR W +LESIFIG DIR+QLP +++
Sbjct: 1455 LMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQ 1514
Query: 1506 KFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAF 1565
+FD+I++ FK +M + +K P + P + L+ + + L C+K+L +YL++KR AF
Sbjct: 1515 RFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAF 1574
Query: 1566 PRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLVSAMISAEG 1622
PRF+F+S +LL IL + +DP+ V H+ K++D++ L+F + D K+ M S E
Sbjct: 1575 PRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKED 1634
Query: 1623 EVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVL 1682
E M F + G+VE W+ VL+ M T R EA+ Y E++ R W+L Y
Sbjct: 1635 EYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWILDYP----- 1688
Query: 1683 AASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742
+Q+WWT EV F + ++G + A+K+Y +K Q++ L+T + L+ DR K T+
Sbjct: 1689 --AQIWWTTEVGLAFARLEEGYENAIKDYNKKQISQLNVLITLLIGNLNAGDRMKIMTIC 1746
Query: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLN 1802
IDVHARD+V I + ++ F W++QLR WD E C Y YEY+G
Sbjct: 1747 TIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
Query: 1803 GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGM 1862
RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG + V NC E M
Sbjct: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
Query: 1863 DYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEI 1922
DY++ G I+ GLAQ GAWGCFDEFNRI VLSVI+ Q++ +++A+ + F F G+ I
Sbjct: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEII 1923
Query: 1923 SLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLA 1982
L +GIFITMNPGYAGR ELPE++KALFRP ++VPD + ICEIML +EGFLEA+ LA
Sbjct: 1924 GLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLA 1983
Query: 1983 KKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLP 2042
+K LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG ED VLMRALRD N+P
Sbjct: 1984 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIP 2043
Query: 2043 KFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFET 2102
K V +D+P+F+GLI DLFP LD PR R +F ++Q + E V KVVQ+ E
Sbjct: 2044 KIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEEL 2103
Query: 2103 MLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRD 2162
+ RH+ +VG GKS V+ +L + L L+PKAV+ EL+GI++P TR+
Sbjct: 2104 LQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTRE 2163
Query: 2163 WTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQ 2222
W DG+ S I R++ T K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L
Sbjct: 2164 WKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
Query: 2223 AHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFE 2282
L+FE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+ NL LF+
Sbjct: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
Query: 2283 KYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LL 2338
KY+P +D + G K I P ++ ++ + +L+ LL + D L
Sbjct: 2283 KYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELY 2333
Query: 2339 ECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---ELPGQLPTLY 2395
E YF+ + + G ++ +D + + V+ W N + P Q T++
Sbjct: 2334 ELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKFPSQ-GTIF 2381
Query: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
D++ D +++PW+ VP + P+ LVHT +T R + ++ +++ PV+ VG
Sbjct: 2382 DYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVG 2441
Query: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
+GT K+ + L++L+ + +V V F+ TTS +Q LE +EK++ YGPP K
Sbjct: 2442 NAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTK 2501
Query: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
+L+ F+DDMNMP VD+YGT P L++ ++ + YDR K L K I + ++A M
Sbjct: 2502 KLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQYVACMNPTS 2560
Query: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVSGKLTFCTL 2633
G +D R F VF V FP +E+L IY++IL H + + +I +S +L L
Sbjct: 2561 GSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAAL 2619
Query: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693
AL++ I PT KFHY+FNLRDLS +F GL+ + E +T +VR+W +E RV+
Sbjct: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYG 2679
Query: 2694 DRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEPRIYEDIQD 2751
D+++ E D++ + + + + F DD+ E++ P +F F + G+P+ Y + D
Sbjct: 2680 DKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDPK-YVPVTD 2735
Query: 2752 YEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQS 2811
L ++L+ YNE N MNLVLF+DA+ H+ R++RI+ RG+ALLVGVGGSGKQS
Sbjct: 2736 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQS 2795
Query: 2812 LSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFL 2871
LSRLAA+ + +VF+I L +GY + DL + Y+K ++N +FL TD+ VAEE FL
Sbjct: 2796 LSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFL 2855
Query: 2872 ELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVL 2931
LIN++L SG +P LF E+E E+I+S + + GM +E+ W++F+ K L ++L
Sbjct: 2856 VLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL 2915
Query: 2932 GMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVK 2991
SPVG LR R FP +VN T IDWF WP AL +V+ FL IP E ++
Sbjct: 2916 CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISF 2975
Query: 2992 HVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGL 3051
+ VH +V+ S+ +L RR NY TPK +L+ I Y LL +K +A+ +RL+ GL
Sbjct: 2976 FMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035
Query: 3052 DKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIE 3111
KL+ Q+D+L KLA Q+ L +K+ + + L++ + + ++K +A+++ +++E
Sbjct: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE 3095
Query: 3112 EQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECIL 3171
NK + ++ ET LA+ P L AA+ L L+K+++TE++SF PP V V ++
Sbjct: 3096 VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVM 3155
Query: 3172 IM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225
I+ K K+ +WK AK +M FL SL + D + I ++ +K K E
Sbjct: 3156 ILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215
Query: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285
+ + S A G+ + ++ + +V+ ++ PKR+ + + +L RI+N++A +
Sbjct: 3216 FIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL 3275
Query: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345
L L + +E A EK K Q+EA+ R ++ A++L+ GL SENIRW ++ +
Sbjct: 3276 NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQG 3335
Query: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLESLLTDDV 3403
V L GD LL +AF+SY G FT ++R+E++ + W I L+ IP++ SLLTDD
Sbjct: 3336 VTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDA 3395
Query: 3404 EISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDP 3463
+++ W +QGLP D +S +N + R+PL +D Q Q + WIK K ++ L+
Sbjct: 3396 DVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQK 3454
Query: 3464 DFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFR 3523
+L +E +I G L ++ E +DPV+D +L +N + +G+ +I +GDKEV+Y FR
Sbjct: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKEVEYHPKFR 3512
Query: 3524 LYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETS 3583
L L+TK NP Y P + + +IN+ VT GLEDQLL+ +VA ER +LE+ + +L + +
Sbjct: 3513 LILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQN 3572
Query: 3584 ENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDR 3643
E K +LK+LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+ T + I+
Sbjct: 3573 EFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINE 3632
Query: 3644 LRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNI 3703
R+ YRPAA R ++L+F+L+++ +N +YQ+SL AF VF +++++ P + + +R+ N+
Sbjct: 3633 ARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINL 3692
Query: 3704 MDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRK 3763
D +T+S+Y + GLFER KL+F +T ++ + + ELDF L+ K+
Sbjct: 3693 TDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF---KAGVV 3749
Query: 3764 KPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823
P +L QGW I LSEM D F L D+E + W++ + ++ E+ P + N
Sbjct: 3750 SPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK 3807
Query: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883
T QKL ++RC R DR+ A+ ++V MG K+V+ + F +E+S+P + I FILS
Sbjct: 3808 -TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILS 3866
Query: 3884 PGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQ----- 3936
PG DP D+ L ++ GF +L +++GQGQE VA L+ A +G W++LQ
Sbjct: 3867 PGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQ 3926
Query: 3937 ---NCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987
N HL+ +WL L+K LER T H D+R++++ +P T P GIL+ ++K+
Sbjct: 3927 HCRNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 3986
Query: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046
EPP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 3987 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4046
Query: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106
FN D + + +L YL + +P++PW L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4047 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4101
Query: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
EY+ GD + ++IP + + + E I+ +P ++GL
Sbjct: 4102 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4149
Query: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQ---------------- 4202
HPNAEIG+ T + ++ +LE+QP+ +S +G+SR++ G
Sbjct: 4150 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELR 4209
Query: 4203 -------------VAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRM 4249
V +I K+P+ F++ ++ + +P VV QE ER N L M
Sbjct: 4210 RGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAK-AAEKTPYVVVAFQECERMNILTNEM 4268
Query: 4250 TKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFS 4309
+SL EL L GE+ ++ +++D++ +LF +P+ W A ++ L W L R
Sbjct: 4269 RRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIR 4328
Query: 4310 QYMLWVTE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEV 4368
+ W T+ + P+ +WL+G P+S+LTA++Q+ RKN WPLD+ L +VTK ++ +++
Sbjct: 4329 ELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDM 4387
Query: 4369 NERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRT 4428
+G +V GL++EGA WD + G + +++ K L +P++ I I R++ +N +
Sbjct: 4388 TAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC 4447
Query: 4429 PVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTL 4468
PVY T +R G V+ +L T + W+L V L L
Sbjct: 4448 PVYKTRIR----GPTYVWTFNLKTKEKAAKWILAAVALLL 4483
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 2284 bits (5919), Expect = 0.0
Identities = 1443/4480 (32%), Positives = 2365/4480 (52%), Gaps = 333/4480 (7%)
Query: 194 QLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMP--IISVEGEVSDLAADPETVDIL--- 248
Q++ ++ + V + + + +++G+ L +P + S++G + + P ++D L
Sbjct: 132 QVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERIPSSLDNLLLH 191
Query: 249 --EQCVINWLNQISTAVE---AQLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVR 303
E +I+W +QI + AQ P E EFW R L +HEQ P V
Sbjct: 192 AIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCIHEQLNRPKVN 251
Query: 304 KVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDT 363
K++++++++ S LQ V+T + + EA+D V +L + + + F ++
Sbjct: 252 KIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQAD-FTMLPTF 310
Query: 364 IPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKT 423
I ++ + +W S +YN R+I +++ +I E ++ + K + +
Sbjct: 311 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 370
Query: 424 LEARNTLRLWKKAY--FD---TRAKIEASGRED-RWEFDRKRLFERTDYMATICQDLSDV 477
+ + K+ Y +D K+ +E WEF F R + Q + ++
Sbjct: 371 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 430
Query: 478 LQILEEFYNIFGPELKAVTGD------PKRIDDVL--------CRVDGLVTPMENLT--- 520
+ EF + EL V G+ + D+V C+ D L N
Sbjct: 431 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 490
Query: 521 ---------------------FDPFS-IKSSQFWKYVMDEFKIEVLI--------DIINK 550
FD S IKSS Y+ LI ++ +
Sbjct: 491 ADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEVAPRYSVMLE 550
Query: 551 IFVQNLEN-----------------PPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQ 593
+F L+N P ++KN PPVAG + W L R++ ++ + V+
Sbjct: 551 LFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEVSMKHLKHVE 610
Query: 594 EILDSDRGQEVK---QKYLEVGRTMKEYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIAT 650
+ S G E K QKY E+ ++ + ++ Y+QW+ +Q + + L+ + + +
Sbjct: 611 HPVMS--GAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLILRDAASN 668
Query: 651 EEPSTLERGAVFAINFSPALREIINETKYLE-QLGFTVPELARNVALQEDKFLRYTAGIQ 709
+ +NFS AL ++ E KYL Q +P+ A ++ + + F ++ ++
Sbjct: 669 ----------LIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLE 718
Query: 710 RMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKF 769
++ Y+ + + E +L+K + + S L WN G+ YI ++ +
Sbjct: 719 LIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNL 778
Query: 770 ESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMV 829
++ + + +N + IS + A LF+ K E L + + ++
Sbjct: 779 QNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALL------------DLDGRIANLN 826
Query: 830 RWYLAIGPLLTKVEGLVV-HTNTGKAPKLA----SYYKYWEKKIYEVLTKLILKNLQSF- 883
+ Y A+ K++ +V + +A L+ Y Y + + + + I K+L
Sbjct: 827 KRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLM 886
Query: 884 -NSLILGNV-PLFHTETILTAPEIILHPNTNEI--DKMCFHCVRNCVEITKHFVRWMNGS 939
N +I ++ PLF L + +P T E+ D+ + V + R +
Sbjct: 887 DNMVIDESIAPLFEIRMELDEDGLTFNP-TLEVGSDRGFLALIEGLVNDIYNVARLI--- 942
Query: 940 CIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK----YLQKWKR 995
P+ ++ +N+ D+ N +IE + V ++IN MK Y ++R
Sbjct: 943 -----PRLAKDR----MNYKMDLEDNTDLIEMR----EEVSSLVINAMKEAEEYQDSFER 989
Query: 996 YRPLWKLDKAIVMEKFAA-------------------KKPPCVA-YDEKLQFYSKIAYEV 1035
Y LW + M+ F K PP +A + E++ Y K+ EV
Sbjct: 990 YSYLWTDNLQEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEV 1049
Query: 1036 MRHPLIKDEH-CIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKN 1094
+ K H ++ R + + W + L+ L +L M+
Sbjct: 1050 SKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMG 1109
Query: 1095 LRKI--PNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVD 1152
L K + L V+ + +++ + + + +++ + Y P+ +
Sbjct: 1110 LTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQ 1169
Query: 1153 KIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD- 1211
++ W+N ++ V+ + ++ + R + + ++ EF +RF E P S D
Sbjct: 1170 ELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDP 1229
Query: 1212 ----DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMI 1267
L+K L G+ E L+ + LF++P+ Y +L +E+ L+ +
Sbjct: 1230 NPYKSLNKVFLLKGIMEA-----------LSKSGGLFEVPVPDYKQLKACHREVRLLKEL 1278
Query: 1268 YELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKA 1327
+++ + + E+W T W ++NV+ + + F + +R L + ++ L+ +K
Sbjct: 1279 WDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKN 1338
Query: 1328 FKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVT 1387
S+ + +L+N A+R+RHW++LM+ T V F+M+E TL ++ + LH + D + IV
Sbjct: 1339 VITSLRAVSELQNPAIRERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVD 1398
Query: 1388 AAIKEVAIEKAVKEILDTWENMKFTVVKYCK-GTQERGYILGSVDEIIQSLDDNTFNLQS 1446
A+KE +EK +K + TW M+F + + GT +L S + ++++L+DN LQ+
Sbjct: 1399 KAVKESGMEKVLKALDSTWSMMEFQHEPHPRTGTM----MLKSSEVLVETLEDNQVQLQN 1454
Query: 1447 ISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAK 1505
+ S+++ FL+ V W++ LS VI IW VQR W +LESIFIG DIR+QLP +++
Sbjct: 1455 LMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQ 1514
Query: 1506 KFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAF 1565
+FD+I++ FK +M + +K P + P + L+ + + L C+K+L +YL++KR AF
Sbjct: 1515 RFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAF 1574
Query: 1566 PRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRF--NDGDSGEKLVSAMISAEG 1622
PRF+F+S +LL IL + +DP+ V H+ K++D++ L+F + D K+ M S E
Sbjct: 1575 PRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKED 1634
Query: 1623 EVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVL 1682
E M F + G+VE W+ VL+ M T R EA+ Y E++ R W+L Y
Sbjct: 1635 EYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPEAVVTY-EEKPREQWILDYP----- 1688
Query: 1683 AASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742
+Q+WWT EV F + ++G + A+++Y +K Q++ L+T + L+ DR K T+
Sbjct: 1689 --AQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTIC 1746
Query: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLN 1802
IDVHARD+V I + ++ F W++QLR WD E C Y YEY+G
Sbjct: 1747 TIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNT 1803
Query: 1803 GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGM 1862
RLVITPLTDR Y+TLTQ+L + +GGAPAGPAGTGKTETTKDL +ALG + V NC E M
Sbjct: 1804 PRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQM 1863
Query: 1863 DYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEI 1922
DY++ G I+ GLAQ GAWGCFDEFNRI VLSVI+ Q++ +++A+ + F F G+ I
Sbjct: 1864 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEII 1923
Query: 1923 SLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLA 1982
L +GIFITMNPGYAGR ELPE++KALFRP ++VPD + ICEIML +EGFLEA+ LA
Sbjct: 1924 GLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLA 1983
Query: 1983 KKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLP 2042
+K LY L +E LSKQ HYD+GLRA+KSVLV+AG LKRG ED VLMRALRD N+P
Sbjct: 1984 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIP 2043
Query: 2043 KFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFET 2102
K V +D+P+F+GLI DLFP LD PR R +F ++Q + E V KVVQ+ E
Sbjct: 2044 KIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEEL 2103
Query: 2103 MLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRD 2162
+ RH+ +VG GKS V+ +L + L L+PKAV+ EL+GI++P TR+
Sbjct: 2104 LQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTRE 2163
Query: 2163 WTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQ 2222
W DG+ S I R++ T K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L
Sbjct: 2164 WKDGLFSTIMRDLANITHDGP-KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2222
Query: 2223 AHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFE 2282
L+FE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+ NL LF+
Sbjct: 2223 RTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFD 2282
Query: 2283 KYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LL 2338
KY+P +D + G K I P ++ ++ + +L+ LL + D L
Sbjct: 2283 KYLPTCLDKLRFG---------FKKITPVPEITVIQTILYLLECLLTEKTVPPDSPRELY 2333
Query: 2339 ECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPG---ELPGQLPTLY 2395
E YF+ + + G ++ +D + + V+ W N + P Q T++
Sbjct: 2334 ELYFVFTCFWAFGGAMFQDQLVDY-----------RVEFSKWWINEFKTIKFPSQ-GTIF 2381
Query: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
D++ D +++PW+ VP + P+ LVHT +T R + ++ +++ PV+ VG
Sbjct: 2382 DYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLVG 2441
Query: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
+GT K+ + L++L+ + +V V F+ TTS +Q LE +EK++ YGPP K
Sbjct: 2442 NAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTK 2501
Query: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
+L+ F+DDMNMP VD+YGT P L++ ++ + YDR K L K I + ++A M
Sbjct: 2502 KLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHK-LTLKDIHNCQYVACMNPTS 2560
Query: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTS--TFHESIVAVSGKLTFCTL 2633
G +D R F VF V FP +E+L IY++IL H + + +I +S +L L
Sbjct: 2561 GSFT-IDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAAL 2619
Query: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693
AL++ I PT KFHY+FNLRDLS +F GL+ + E +T +VR+W +E RV+
Sbjct: 2620 ALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYG 2679
Query: 2694 DRLISETDKQLVQQHIGSLVVEHFKDDV--EVVMRDPILFGDFQMALHEGEPRIYEDIQD 2751
D+++ E D++ + + + + F DD+ E++ P +F F + G+P+ Y + D
Sbjct: 2680 DKMVDEKDQETLHR-VTMASTKKFFDDLGDELLFAKPNIFCHFAQGI--GDPK-YVPVTD 2735
Query: 2752 YEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQS 2811
L ++L+ YNE N MNLVLF+DA+ H+ R++RI+ RG+ALLVGVGGSGKQS
Sbjct: 2736 MAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQS 2795
Query: 2812 LSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFL 2871
LSRLAA+ + +VF+I L +GY + DL + Y+K ++N +FL TD+ VAEE FL
Sbjct: 2796 LSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFL 2855
Query: 2872 ELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVL 2931
LIN++L SG +P LF E+E E+I+S + + GM +E+ W++F+ K L ++L
Sbjct: 2856 VLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVIL 2915
Query: 2932 GMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVK 2991
SPVG LR R FP +VN T IDWF WP AL +V+ FL IP E ++
Sbjct: 2916 CFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISF 2975
Query: 2992 HVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGL 3051
+ VH +V+ S+ +L RR NY TPK +L+ I Y LL +K +A+ +RL+ GL
Sbjct: 2976 FMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGL 3035
Query: 3052 DKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIE 3111
KL+ Q+D+L KLA Q+ L +K+ + + L++ + + ++K +A+++ +++E
Sbjct: 3036 MKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVE 3095
Query: 3112 EQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECIL 3171
NK + ++ ET LA+ P L AA+ L L+K+++TE++SF PP V V ++
Sbjct: 3096 VINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVM 3155
Query: 3172 IM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE 3225
I+ K K+ +WK AK +M FL SL + D + I ++ +K K E
Sbjct: 3156 ILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPE 3215
Query: 3226 EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAI 3285
+ + S A G+ + ++ + +V+ ++ PKR+ + + +L RI+N++A +
Sbjct: 3216 FIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAEL 3275
Query: 3286 QKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRR 3345
L L + +E A EK K Q+EA+ R ++ A++L+ GL SENIRW ++ +
Sbjct: 3276 NANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQG 3335
Query: 3346 VKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLESLLTDDV 3403
V L GD LL +AF+SY G FT ++R+E++ + W I L+ IP++ SLLTDD
Sbjct: 3336 VTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDA 3395
Query: 3404 EISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDP 3463
+++ W +QGLP D +S +N + R+PL +D Q Q + WIK K ++ L+
Sbjct: 3396 DVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNK-YRSELKAIRLGQK 3454
Query: 3464 DFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFR 3523
+L +E +I G L ++ E +DPV+D +L +N + +G+ +I +GDKEV+Y FR
Sbjct: 3455 SYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRN-TIKKGK-YIKIGDKEVEYHPKFR 3512
Query: 3524 LYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETS 3583
L L+TK NP Y P + + +IN+ VT GLEDQLL+ +VA ER +LE+ + +L + +
Sbjct: 3513 LILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQN 3572
Query: 3584 ENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDR 3643
E K +LK+LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+ T + I+
Sbjct: 3573 EFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINE 3632
Query: 3644 LRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNI 3703
R+ YRPAA R ++L+F+L+++ +N +YQ+SL AF VF +++++ P + + +R+ N+
Sbjct: 3633 ARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINL 3692
Query: 3704 MDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRK 3763
D +T+S+Y + GLFER KL+F +T ++ + + ELDF L+ K+
Sbjct: 3693 TDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF---KAGVV 3749
Query: 3764 KPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNN 3823
P +L QGW I LSEM D F L D+E + W++ + ++ E+ P + N
Sbjct: 3750 SPVDFLQHQGWGGIKALSEM--DEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK 3807
Query: 3824 ITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILS 3883
T QKL ++RC R DR+ A+ ++V MG K+V+ + F +E+S+P + I FILS
Sbjct: 3808 -TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILS 3866
Query: 3884 PGSDPATDLMKLAERSGF--GGNRLKFLAMGQGQEKVALQLLETAVARGQWLMLQ----- 3936
PG DP D+ L ++ GF +L +++GQGQE VA L+ A +G W++LQ
Sbjct: 3867 PGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQ 3926
Query: 3937 ---NCHLLVKWLKDLEKSLERI-TKPHPDFRLWLTTDP-----TKGFPIGILQKSLKVVT 3987
N HL+ +WL L+K LE T H D+R++++ +P T P GIL+ ++K+
Sbjct: 3927 HCRNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 3986
Query: 3988 EPPNGLKLNMRATYFKISHEMLDQC-PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYY 4046
EPP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 3987 EPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSY 4046
Query: 4047 DFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYM 4106
FN D + + +L YL + +P++PW L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4047 PFNNGDLTISINVLYNYL-----EANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYL 4101
Query: 4107 DEYL------GDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
EY+ GD + ++IP + + + E I+ +P ++GL
Sbjct: 4102 AEYIRTEMLEGDVLL------------APGFQIPPNLDYKGYHEYIDENLPPESPYLYGL 4149
Query: 4161 HPNAEIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQ---------------- 4202
HPNAEIG+ T + ++ +LE+QP+ +S +G+SR++ G
Sbjct: 4150 HPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELR 4209
Query: 4203 -------------VAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRM 4249
V +I K+P+ F++ ++ + +P VV QE ER N L M
Sbjct: 4210 RGGCPGTGFQVKAVLDDILEKIPETFNMAEIMAK-AAEKTPYVVVAFQECERMNILTNEM 4268
Query: 4250 TKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFS 4309
+SL EL L GE+ ++ +++D++ +LF +P+ W A ++ L W L R
Sbjct: 4269 RRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIR 4328
Query: 4310 QYMLWVTE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEV 4368
+ W T+ + P+ +WL+G P+S+LTA++Q+ RKN WPLD+ L +VTK ++ +++
Sbjct: 4329 ELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDM 4387
Query: 4369 NERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRT 4428
+G +V GL++EGA WD + G + +++ K L +P++ I I R++ +N +
Sbjct: 4388 TAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYEC 4447
Query: 4429 PVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTL 4468
PVY T +R G V+ +L T + W+L V L L
Sbjct: 4448 PVYKTRIR----GPTYVWTFNLKTKEKAAKWILAAVALLL 4483
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 2199 bits (5699), Expect = 0.0
Identities = 1267/3673 (34%), Positives = 2035/3673 (55%), Gaps = 131/3673 (3%)
Query: 878 KNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRW-- 935
++ S +++ ++P+F L P I++ P ++ + V + + K +W
Sbjct: 994 RDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSS 1053
Query: 936 ----------------MNGSCIECPPQKGEEE-----EVVIIN---------FYNDISLN 965
+ + + GE E E+ +N +Y ++S N
Sbjct: 1054 ELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSEN 1113
Query: 966 PQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKL 1025
+I++ ++ ++ ++ + +KRY +W+ K ++ F + P ++ ++
Sbjct: 1114 KEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQI 1173
Query: 1026 QFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLH 1085
++ + E+ P I L L + K+W++ +G+ N+ + E+ N+
Sbjct: 1174 LYFQNLEQEINAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIF 1233
Query: 1086 EEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPD 1145
+E K L + L+D++ +A + EIR + + ++ + ++E Y + Y L
Sbjct: 1234 MLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAR 1293
Query: 1146 AEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG 1205
E + VD + W L + V++ L ++ +F + + + +F + G
Sbjct: 1294 EEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNG 1353
Query: 1206 PGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLR 1265
P + G + + L +++ + + E+LF LP T YP+LL+++K+++ L+
Sbjct: 1354 PMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQ 1413
Query: 1266 MIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKM 1325
IY LY + + LW +N++ + + F RKLPR ++ L+ +
Sbjct: 1414 KIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKII 1473
Query: 1326 KAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEM-TETFTLENMFAMELHKHTDVLNE 1384
F + PLL + ++A+ +RHW+ + T ++ E+F L N+ L K+ + + +
Sbjct: 1474 DDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIED 1533
Query: 1385 IVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYIL---GSVDEIIQSLDDNT 1441
I +A+KE IE+ +K++++ W+N FT + + RG +L S EII +++D+
Sbjct: 1534 ICISAVKERDIEQKLKQVINEWDNKTFTFGSF----KTRGELLLRGDSTSEIIANMEDSL 1589
Query: 1442 FNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLP 1501
L S+ +R+ PF + KW + LS ++IE WM VQ W+YLE++F+GGDI QLP
Sbjct: 1590 MLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLP 1649
Query: 1502 EEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDL-QNVSEGLEKCQKSLNDYLDS 1560
+EAK+F NIDK + +IM + P + +CC L L ++ + LE CQKSL YL+
Sbjct: 1650 KEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEK 1709
Query: 1561 KRNAFPRFFFISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMIS 1619
KR FPRFFF+SD LL ILG +SD +Q H++ ++DNI S++F+ EK+ ++S
Sbjct: 1710 KRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFH-----EKIYDRILS 1764
Query: 1620 A---EGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRV-DWMLL 1675
EGE +E K + AEG VE W+ ++L E + + L+ ++A E ++ +++
Sbjct: 1765 ISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSS 1824
Query: 1676 YQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDR 1735
+ V L Q+ WT + E+ A K +K+ M+ + ++ L+ T LS +R
Sbjct: 1825 FPAQVGLLGIQMIWTRDSEEALRNA-KFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTER 1883
Query: 1736 KKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYG 1795
KY T++ I VH RDI D I +F+W Q RFY++ + D++ I F Y
Sbjct: 1884 VKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQ 1943
Query: 1796 YEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVV 1855
E++G RLVITPLTDR Y+TL QAL M +GGAPAGPAGTGKTETTKD+ + LG VV
Sbjct: 1944 NEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVV 2003
Query: 1856 TNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTF 1915
NC + MD+R +G+IF GLAQ G+WGCFDEFNRID VLSV + QI I +F
Sbjct: 2004 FNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSF 2063
Query: 1916 QF-EGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEG 1974
F +G ++++ G+F+TMNPGYAGR ELPE++K FR V ++VPD Q I + L S G
Sbjct: 2064 IFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCG 2123
Query: 1975 FLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMR 2034
F++ LA+K LYKL EQLSKQ HYDFGLR + SVL G KR + E ++MR
Sbjct: 2124 FIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMR 2183
Query: 2035 ALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVD 2094
LRDMNL K + ED PLFL LI DLFP + + YP+ A+ + +EE G P
Sbjct: 2184 VLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKL 2243
Query: 2095 KVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYG 2154
KV+Q+FET RH M +GP+ GK+ I+TL +A T G + +NPKA++ +++G
Sbjct: 2244 KVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFG 2303
Query: 2155 ILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLA 2214
LD T DWTDG+ S ++R+ + K E +I+ DG VDA+W+EN+NSV+DDN+ LTLA
Sbjct: 2304 RLDVATNDWTDGIFSTLWRKTLR-AKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLA 2362
Query: 2215 NGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQ 2274
NG+RI + +C ++FE ++ ASPATVSR GMV++ L + P + ++ + + E
Sbjct: 2363 NGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKK-RSPQEA 2421
Query: 2275 YNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIED 2334
L L+ + P L ++ + + E L+ V +NM+ L + + GE+
Sbjct: 2422 EILRQLYTESFPDLYRFCIQNLE--YKMEVLEAFVITQSINMLQGLIPLKEQ--GGEVSQ 2477
Query: 2335 LDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTL 2394
L F+ AL S GA+L DGR + + ++ R T++ A PG+ T
Sbjct: 2478 AHLGRL-FVFALLWSAGAALELDGRRRLELWL-RSRPTGTLELPPP-AGPGD------TA 2528
Query: 2395 YDFHFDNKRNQWVPWSKLVPEYIHAPER--KFINILVHTVDTTRTTWILEQMVKIKQPVI 2452
+D++ W W+ EY++ + ++ +ILV VD RT ++++ + K + V+
Sbjct: 2529 FDYYVAPD-GTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVL 2587
Query: 2453 FVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPP 2512
+GE GT+KT + F+ E +++ +NFSS TT + QR +E+ V+KR TYGPP
Sbjct: 2588 LIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPP 2647
Query: 2513 MGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMG 2572
GK++ VF+DD+NMP ++E+G Q +++ L+E+ Y+ K SI D+ F+AAM
Sbjct: 2648 AGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMI 2707
Query: 2573 KAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTST---FHESIVAVSGKLT 2629
GGGRN++ R FS+FN PSE S+ I+ I GH T F E + KL
Sbjct: 2708 HPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLV 2767
Query: 2630 FCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECL 2689
T L++ + PTP+KFHY+FNLRDLSRV+ G++ T E + ++++W++EC
Sbjct: 2768 PLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECK 2827
Query: 2690 RVFHDRLISETDKQLVQQHIGSLVVEHFKDDVEVV------------MRD-PILFGDFQM 2736
RV DR +D + + SLV E F ++ +++ +RD P G+
Sbjct: 2828 RVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSE 2887
Query: 2737 ALHEGEPRIYEDIQDYEAAKALFQEILEEYNES--NTKMNLVLFDDALEHLTRVHRIIRM 2794
P+IYE I+ + K L+ YNES M++V F DA+ HL ++ R+IR
Sbjct: 2888 EADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRT 2947
Query: 2795 DRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENK 2854
+G+ALLVGVGGSGKQSL+RLA+F A F+I L+R Y+ ++ EDLK LY G + K
Sbjct: 2948 PQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGK 3007
Query: 2855 AMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMG--PAK 2912
+ F+FTD + +E FLE +NN+L+SG V LF+ +E + I S + K+ P
Sbjct: 3008 GITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTN 3067
Query: 2913 ESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAK 2972
E++ YF+++ NLHIVL SPVG+ R FP +++ IDWF WP AL AV++
Sbjct: 3068 ENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSE 3127
Query: 2973 SFL-GYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSK 3031
FL Y+ E + VV+ + V + Q+ RRS +VTPK+YL FI Y
Sbjct: 3128 HFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKF 3187
Query: 3032 LLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAV 3091
+ EK R++ GL+KLKEA+ + L+++L ++ L + + +L+E+ +
Sbjct: 3188 IYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTM 3247
Query: 3092 NTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT 3151
AE+ K ++ + I+ +KA AE L P LE A+ LQ + SD+
Sbjct: 3248 KAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIA 3307
Query: 3152 EIRSFAKPPKQVQTVCECILIM-------------KGYKELNWKTAKGVMSDPNFLRSLM 3198
+R+ +PP + + +C+L++ K +W+ + +M+ NFL++L
Sbjct: 3308 TVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQ 3367
Query: 3199 EIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKR 3258
+ D+I + ++ + + + E + V G+ + +A+ + + +E+ P +
Sbjct: 3368 QFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLK 3427
Query: 3259 EKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLI 3318
+ E L ++L++ Q EL Q EL+ + A+YE A+ EKQ L E+AE ++
Sbjct: 3428 ANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQ 3487
Query: 3319 AADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIW 3378
A LISGL E RW E + +L+GD LL AFLSY G F EFRD ++N W
Sbjct: 3488 TASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-W 3546
Query: 3379 QNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDP 3438
+ ++ R+IP + L +L D IS W QGLP D+LS+QNGI+ T+ASR+PL IDP
Sbjct: 3547 RKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDP 3606
Query: 3439 QQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEK 3498
Q Q WIK KE +N L++ S N F LE S+ G P L DV E +DP +DNVLE+
Sbjct: 3607 QTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLER 3666
Query: 3499 NIKVSQGRQFII-LGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLED 3557
N + G F + +GDKEVD FRLY+ TKL NP Y+P + + +I++TVT+KGLED
Sbjct: 3667 NF-IKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLED 3725
Query: 3558 QLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTL 3617
QLL ++ E++ELE++R HL+++ + NK +K+LED+LL L ++ G+++++ L+ L
Sbjct: 3726 QLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVL 3785
Query: 3618 EETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLI 3677
TK A EV++KL+++ +T + I+ R+ YRP A RG+IL+F+++EM LVN MYQ SL
Sbjct: 3786 SNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLR 3845
Query: 3678 AFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQ 3737
FL +F LSL +S+ I KR+ NI++ +T+ +Y + GL+E HK LF+ +T+KI+
Sbjct: 3846 QFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDI 3905
Query: 3738 AEGRVPQEELDFFLKGNISLE-KSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVE 3796
RV EE +KG SL+ K+ KP W+ D W +++ LS++ F + D +
Sbjct: 3906 QRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKL--RQFSDVLDQIS 3963
Query: 3797 NNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEK 3856
N+ +W+ W+D ++ E+ P+P YD ++ F++LL++R + DR Y+ +MGEK
Sbjct: 3964 RNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEK 4023
Query: 3857 YVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQE 3916
Y + ++ E +E+S P +P++ +LS GSDP ++ L +R ++++MGQGQE
Sbjct: 4024 YAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKI---ETRYVSMGQGQE 4080
Query: 3917 KVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPI 3976
A +LL+ +A G W +LQNCHL + ++ +L + H FRLW+TT+ K FPI
Sbjct: 4081 VHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPI 4140
Query: 3977 GILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRK 4036
+LQ S+K +PP GL+ ++ TY +S ++LD +KP++Y +AF H+ VQERRK
Sbjct: 4141 TLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRK 4200
Query: 4037 FGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDS 4096
FG +GWN+ Y+FN++DF ++ + +L ++ + W +++Y+IGE+ YGGR D
Sbjct: 4201 FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKG--VSWTTIRYMIGEIQYGGRVTDD 4258
Query: 4097 FDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPE 4156
+D+R+L + + + +F F F++ Y IP + +++ I++LP ++PE
Sbjct: 4259 YDKRLLNTFAKVWFSENMFG--PDFSFYQG----YNIPKCSTVDNYLQYIQSLPAYDSPE 4312
Query: 4157 VFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFD 4216
VFGLHPNA+I Y ++ A+D+ +L +QP+ +R+ + ++A ++ K+P +
Sbjct: 4313 VFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYV 4372
Query: 4217 LDQVRKRLGT--GLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVA 4274
+V++RL P ++ L QE++R +++ + +L EL+ A+ G + MS L D
Sbjct: 4373 PFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDAL 4432
Query: 4275 RSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESY 4334
+F IP W++ A +LG W + R SQ+ WV P W++G P+ +
Sbjct: 4433 DCMFDARIPAWWKK-ASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGF 4491
Query: 4335 LTALVQATCRKN-GWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKG 4393
LTA+ Q R N GW LD L +VTK+ D+++ +G +V GLYLEGA WD
Sbjct: 4492 LTAMRQEITRANKGWALDNMVLCNEVTKWM-KDDISAPPTEGVYVYGLYLEGAGWDKRNM 4550
Query: 4394 CLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTT 4453
LI+SKPKVL +P+++I E + L+ + P+Y +R + + + DL T
Sbjct: 4551 KLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSCPIYKKPVRTD---LNYIAAVDLRTA 4606
Query: 4454 RHISHWVLQGVCL 4466
+ HWVL+GV L
Sbjct: 4607 QTPEHWVLRGVAL 4619
Score = 180 bits (456), Expect = 3e-44
Identities = 164/741 (22%), Positives = 323/741 (43%), Gaps = 110/741 (14%)
Query: 100 VFFLR-NTKEAISEATDMKEAMEIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQHR 158
VFF+R + +AI+ +E M + + G++N+ ++ ++ +F+PAL H
Sbjct: 128 VFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNS-----VRRLLSDIFIPALRATSHG 182
Query: 159 TSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQL 218
G+ + +N IR EFL +++ F + + + L
Sbjct: 183 WGELEGLQ--DAAN-----------------------IRQEFLSSLEGFVNVLSGAQESL 217
Query: 219 EGEIKL------EMPIISVEGEVSDLAADPETVDILEQCVINWLNQIST--AVEAQLKKT 270
+ ++ L E+ + + LA +PET+ +E C+ W+ Q A QL K
Sbjct: 218 KEKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKE 277
Query: 271 PQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKF 330
GP AE+E W++R + + L EQ K P V+ VL V+ + S L+ + + +
Sbjct: 278 ADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDA 337
Query: 331 HTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPL 390
EA DNV++L T+E+ + + S ++D IP +++A++M++ IS +YN E++ L
Sbjct: 338 TNEAKDNVKYLYTLEKCCDPL-YSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSL 396
Query: 391 MERIAWEIAERVCRVV----NLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEA 446
++ +I C+ +++ + + + K L A + ++ + T+ K++
Sbjct: 397 FVKVTNQIIS-ACKAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQ 455
Query: 447 SGREDRWEFDR-----------KRLFERTDYMATI----------CQDLSD--------V 477
+ +++F +RL + D T+ + L D V
Sbjct: 456 NPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMATKYQGIV 515
Query: 478 LQILEEFYNIFGP----------ELKAVTGD-----PKRIDDVLCRVDG------LVTPM 516
I ++ YN E T D K +D ++ ++
Sbjct: 516 ATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKF 575
Query: 517 ENLTFDPFSIKSSQFWKYVMDEFKIEVLIDIINKIFVQNLENPPLYKNHPPVAGAIYWER 576
E L I ++ +++ + + ID+I+K++ + +PPL +N PP+AG I W R
Sbjct: 576 ERLNIPNLGIDDK--YQLILENYGAD--IDMISKLYTKQKYDPPLARNQPPIAGKILWAR 631
Query: 577 SLFFRIKHTILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPA 636
LF RI+ + FQ+ +L + + + + Y + + + E+E + W+ E++
Sbjct: 632 QLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVG 691
Query: 637 LMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVAL 696
L ++S+ + P T G +F +NF P + + ET+ + Q+G V LA ++
Sbjct: 692 L-------EASLLVKAPGT---GELF-VNFDPQILILFRETECMAQMGLEVSPLATSLFQ 740
Query: 697 QEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIG 756
+ D++ R + ++ ML Y + + A L+ H ++ + G L W SL I
Sbjct: 741 KRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIE 800
Query: 757 DYITGCKQAIGKFESLVHQIH 777
Y+ I E L+ +++
Sbjct: 801 AYLENTFAKIKDLELLLDRVN 821
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2172 bits (5627), Expect = 0.0
Identities = 1276/3693 (34%), Positives = 2039/3693 (55%), Gaps = 167/3693 (4%)
Query: 891 VPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIEC--PPQKG 948
+P+F TE +LT ++ P+ + V +C + S + P
Sbjct: 510 IPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSPYIN 569
Query: 949 EEEE-------VVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWK 1001
+ E + + D II Q I + + + Y +++++ +K
Sbjct: 570 NKLEGKTCGTGPSLAAVFEDDKNFHTIISQ---IKETIQAAFESARIYAATFEKFQIFFK 626
Query: 1002 LDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQEN 1061
++++ ++ ++P + E+L+ Y K + + ++ + + R L + +
Sbjct: 627 ENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREKLIPS 686
Query: 1062 AKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLV 1121
+ L +L +K+++ + E + L +P T + L + EI+ +
Sbjct: 687 PLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEIQERIES 746
Query: 1122 MELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTE 1181
+E V + Y+ M Y + P + + ++ + N ++ ++GD + + +
Sbjct: 747 LEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNA---IDKSVGDRESSIKQ 803
Query: 1182 LT---RGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELA 1238
++ ++ E + + D DK +L + LA +K +
Sbjct: 804 FCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQKRAFQYK 863
Query: 1239 NAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGI 1298
+ +K F + ++ + L +V E+ +++++ + ++EW ++ + L+ ++L +
Sbjct: 864 SYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQV 923
Query: 1299 EGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVF 1358
+ + + +L + + SV L+ K++ K+ +P+++DL+N L+ RHW + +
Sbjct: 924 SKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDAT 983
Query: 1359 FEMTET-FTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYC 1417
E TLE + + + + +I A E A+E +K++ D+W+ +F ++ +
Sbjct: 984 LVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHR 1043
Query: 1418 KGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIW 1477
+ILG D+I LDD+T N+ +++ SR++GP V +W+K L+L + +E W
Sbjct: 1044 DSKDV--FILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEW 1101
Query: 1478 MLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRL 1537
+ QR W+YLESIF DI+ QLP EAK F +DK +K IM + + P R P L
Sbjct: 1102 LTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLL 1161
Query: 1538 SDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMY 1596
QN + L++ QK L YL+SKR FPRF+F+S+DELL IL + +P VQ H+ K +
Sbjct: 1162 ETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCF 1221
Query: 1597 DNIASLRFN------------DGDSGEKL----VSAMISAEGEVMEFRKILRAEGRVEDW 1640
D+I+ L F DG+ EK+ + AM+S EGE + K L+A G VE+W
Sbjct: 1222 DSISKLEFALMPPAEGKIPGIDGEP-EKVYTNDILAMLSPEGERVSLGKGLKARGNVEEW 1280
Query: 1641 MTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLL-YQGMVVLAASQVWWTWEVEDVFHK 1699
+ V M + R + K AI Y + + R DW++ + V+L SQ+ W ++ +
Sbjct: 1281 LGKVEEAMFTSLRRLCKAAIADY-QGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLET 1339
Query: 1700 AQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGS 1759
QA+KN+ + +++ L + L K R ++ IDVHARDIV ++
Sbjct: 1340 EHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSK 1399
Query: 1760 ILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLT 1819
+ FDW+ QLR+YWD + D R + YGYEY+G RLVITPLTDR YL L
Sbjct: 1400 VETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLM 1459
Query: 1820 QALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGA 1879
AL + LGGAPAGPAGTGKTETTKDLAKAL + CVV NC +G+DY+ +G+ FSGLAQ GA
Sbjct: 1460 GALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGA 1519
Query: 1880 WGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYA 1939
W CFDEFNRID VLSVI+ Q+ TIRNA +L+ F FEG+EI L FITMNPGYA
Sbjct: 1520 WCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYA 1579
Query: 1940 GRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQ 1999
GRTELP+++KALFRP ++VP+ I E++L+SEGF +K LA+KMT +YKL EQLS+Q
Sbjct: 1580 GRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQ 1639
Query: 2000 YHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDL 2059
HYDFG+RA+KSVLVMAG LKR + DL EDVVL+RAL+D NLPKF+ +D LF G+ISDL
Sbjct: 1640 DHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDL 1699
Query: 2060 FPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGK 2119
FPG+ P Y + V+ V KV+Q +ETML RH M+VGPT GGK
Sbjct: 1700 FPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGK 1759
Query: 2120 SVVINTLCQA---QTKLGL------TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSN 2170
+ V L + KLG+ K Y+LNPK++++ ELYG ++ T +W DG+++
Sbjct: 1760 TTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMAL 1819
Query: 2171 IFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFE 2230
R T ++ K+I+ DG VDALW+ENMN+V+DDN++L LAN ERI+L +LFE
Sbjct: 1820 SVRAAVNDT-SEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFE 1878
Query: 2231 VGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKV----EQYNLNSLFEKYVP 2286
V DL+ ASPATVSRCGMV+VDP+ LK+ PY K W+ I K+ ++Y LN LF++YV
Sbjct: 1879 VQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILN-LFQRYVD 1937
Query: 2287 YLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEG--------EIEDLDLL 2338
+ I +K +PQ D++ VT L +L++L+ G E L+ +
Sbjct: 1938 EGLHFI---------NKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTI 1988
Query: 2339 ECY-FLEALYCSLGASLLEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDF 2397
C F+ SLG +L E+ FD +I+ NP L+
Sbjct: 1989 LCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD----------DNPDARLPNSGDLWSI 2038
Query: 2398 HFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGES 2457
H D + PW +++P + + + F +LV T DT R +++E+++ +K V+F G +
Sbjct: 2039 HMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGIT 2098
Query: 2458 GTSKTATTQNFLKNLSEETNIV-LMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKR 2516
G K+ + L + E V + +NFS++T+S Q +E+ +E++ K+ G P KR
Sbjct: 2099 GVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKR 2158
Query: 2517 LLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG 2576
+++F+DD+NMPR+D YG+Q PI LL+ + G YDR K L K I+D+ I+A GG
Sbjct: 2159 IVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK-LFWKEIQDVTIISACAPPGG 2217
Query: 2577 GRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALY 2636
GRN V PRFI FS+ +P PSE SL I+ +IL G S F ++ + + ++ +Y
Sbjct: 2218 GRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIY 2277
Query: 2637 KNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRL 2696
+ DL PTP+K HY+FNLRDLS+ G++ +P + Q+ R++ +EC RVFHDRL
Sbjct: 2278 NKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRL 2337
Query: 2697 ISETDKQLVQQHIGSLVVEHF--KDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEA 2754
I+ DK + + +HF D+E + PI+FGDF + RIY+D+ D E
Sbjct: 2338 INNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEK 2397
Query: 2755 AKALFQEILEEYNESNTK-MNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLS 2813
+ Q+ L++YN +N K + LV F DA+EH++R+ R+IR +RG+ALLVGVGG+GKQSL+
Sbjct: 2398 TANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLT 2457
Query: 2814 RLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLEL 2873
RLAA + +I LSRGY+ +SF EDL+ LY G+E+K M+FLFTD + E FLE
Sbjct: 2458 RLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLED 2517
Query: 2874 INNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPA-KESVWQYFVNKSANNLHIVLG 2932
INN+L SG VP LF ++E E +L+ A + G+ ++ V+QYF++K LHIVL
Sbjct: 2518 INNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLC 2577
Query: 2933 MSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKH 2992
MSPVG+ R+ CR FP +VN IDWF+ WP +AL +V+K+F E E +
Sbjct: 2578 MSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLM 2637
Query: 2993 VVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLD 3052
V VH SV ++++ +LRR Y TP +YL+ IN Y +L EK + I+ R+ GL
Sbjct: 2638 CVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLT 2697
Query: 3053 KLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEE 3112
KL E I +D++ L+ + VL KS EAL+E++AV+ A++ + +E +
Sbjct: 2698 KLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKV 2757
Query: 3113 QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILI 3172
+ + +A+ L E +P L+AA L LDK+D++EIR F KPP V TV E I I
Sbjct: 2758 KAEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISI 2817
Query: 3173 MKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSK 3232
+ K +W +AK ++ D NFL+ L+E D ++I + ++ + + E++E VSK
Sbjct: 2818 LLNAKP-DWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSK 2876
Query: 3233 AGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETL 3292
A M +V A+ Y V + ++PKR+K+ + +T L Q L ++ +++ L
Sbjct: 2877 ACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQAL 2936
Query: 3293 GAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDC 3352
+Y+ + EK+ L + + + RL+ A KL + L E +RW + + + G+
Sbjct: 2937 QDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNV 2996
Query: 3353 LLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQG 3412
+ AA ++Y GAFT ++R ++ W D EIP+ F L ++L D EI +W + G
Sbjct: 2997 FIAAACVAYYGAFTAQYRQSLI-ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDG 3055
Query: 3413 LPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMS 3472
LP D +S +NGIL T+ R+PL IDPQ QA WI+ KE K+ L++ D +FL+ LE S
Sbjct: 3056 LPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENS 3115
Query: 3473 IKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLAN 3532
I+ G P L ++ E +DP ++ +L K I +S GR I LGD ++DYD NFR Y+ TK+ N
Sbjct: 3116 IRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPN 3175
Query: 3533 PRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDL 3592
P Y P V K +IN+TVT GLEDQLLS +V E+ LEEQR LI + +KN LK +
Sbjct: 3176 PHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTI 3235
Query: 3593 EDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAA 3652
E+ +LR L TS GN+LDN +L+ TL+++K + + +L+ AE T I+ R+ YRP A
Sbjct: 3236 EEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVA 3295
Query: 3653 RRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIY 3712
+G++++FV++ ++ ++ MYQYSL F ++F +++ S+ L +RL +++ + Y
Sbjct: 3296 TQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAY 3355
Query: 3713 NHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCA-WLSD 3771
+ GLFE+HKL++SF + +++ + +G + E +FFL+G+ LEK + KP A WL
Sbjct: 3356 VNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPT 3415
Query: 3772 QGWEDIILLSEMFSDNFGQLPDDVEN-------------NQTVWQEW-----------YD 3807
W L E F G + + + N W+ + +
Sbjct: 3416 ATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQE 3475
Query: 3808 LDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEA 3867
++ Q P G ++ F KL++++C + ++V A+TD+V +G+++++ P +
Sbjct: 3476 KEAAHQDPWSAG----LSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPT 3531
Query: 3868 IFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAV 3927
+++ + ++P+VFILS GSDP + A SG+ R++ +++GQGQ +A ++++ A+
Sbjct: 3532 LYQDMSCNTPLVFILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAM 3590
Query: 3928 ARGQWLMLQNCHLLVKWLKDLEKSLERITKP----HPDFRLWLTTDPTKGFPIGILQKSL 3983
G W+ LQNCHL V W+ +E+ ++ T P FRL+L++ P+ FP+ +LQ S+
Sbjct: 3591 KSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSV 3650
Query: 3984 KVVTEPPNGLKLNMRATYFKISHEMLDQ-CPHPAFKPLVYVLAFFHAVVQERRKFGKIGW 4042
KV EPP GL+ N+R + +++ ++ ++ +++ + FFHA++QER+KFG +GW
Sbjct: 3651 KVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGW 3710
Query: 4043 NVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRIL 4102
N+ Y+FN+SD + + L Y ++ +IPW +L Y+ GE+ YGGR DS+D+R L
Sbjct: 3711 NICYEFNDSDRECALLNLKLYC------KEGKIPWDALIYITGEITYGGRVTDSWDQRCL 3764
Query: 4103 TIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHP 4162
+ + F +T + + + + Y P+ D ++F + IE LPL + PE+FG+H
Sbjct: 3765 RTILKRF---FSPETLEEDYKYSESGI-YFAPMADSLQEFKDYIENLPLIDDPEIFGMHE 3820
Query: 4163 NAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVR- 4221
NA + + + + +LE+QP++ G S D+ + ++ ++ ++P+ +++
Sbjct: 3821 NANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASE 3880
Query: 4222 ----KRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSL 4277
K L L+ + VL QE++RFN L+ + SL L +A+AG V MS E++ V S
Sbjct: 3881 SLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSF 3940
Query: 4278 FIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTA 4337
+P +W A +LK LG+W+ + R S LW+ +P W+SG P+ +LT
Sbjct: 3941 LNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTG 4000
Query: 4338 LVQATCRKNGWPLDR-STLFTQVTKFQDADEVNERA-----GQ-------------GCFV 4378
+Q RK P+D S ++ + ++D V E A GQ G V
Sbjct: 4001 TLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLV 4060
Query: 4379 SGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRN 4438
G++++ + WD ++ + + P + LP++ P + ++ + P+Y T R
Sbjct: 4061 HGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAG 4119
Query: 4439 AM-----GVGLVFEADLFTTRHISHWVLQGVCL 4466
+ V L + R +W+ +G L
Sbjct: 4120 TLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSAL 4152
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 2159 bits (5595), Expect = 0.0
Identities = 1404/4476 (31%), Positives = 2329/4476 (52%), Gaps = 257/4476 (5%)
Query: 149 LPALSFNQHRTSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFA 208
LPALS H ++ + +SN + H+S + +EYH I++++ + + K +
Sbjct: 151 LPALSLG-HVSAFLDEILVPVLSNKNNHKS-WSCFTSQDMEYH-IEVMKKKMYIFRGKMS 207
Query: 209 SNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINWLNQISTAVEAQ-L 267
+ + G++ L+ E + + + +E VI W +QI +E +
Sbjct: 208 RRTLLPIPTVAGKMDLDQNC----SENKPPSNERIILHAIESVVIEWSHQIQEIIERDSV 263
Query: 268 KKTPQGK--GPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFT 325
++ G P AE++FW R LS +++Q + P+V K++ ++ S L+ +F
Sbjct: 264 QRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFL 323
Query: 326 ELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDE 385
+ EA D +L + R+ + + + F I + + ++W S+ YN
Sbjct: 324 AVENALLEAQDVELYLRPLRRHIQCLQE-TEFPQTRILIAPLFHTICLIWSHSKFYNTPA 382
Query: 386 RMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIE 445
R+I L++ + ++ L + + K A N L+ +K ++F+ R K+
Sbjct: 383 RVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLA 442
Query: 446 A--SGREDR-WEFDRKRLFERTDYMATICQDLSDVLQILEEFYNI----FGPELKAV--- 495
+ GR+ R W+F +F R D + D+ EF + FG A+
Sbjct: 443 SYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNG 502
Query: 496 -------------------TGDP-----------------------KRIDDVLCRV---- 509
T DP +R+ ++C
Sbjct: 503 QVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNC 562
Query: 510 DGLVTPMENLT-FDPFSIKS------SQFWKYVMDEFKIEVLIDIINKIFVQNLE----- 557
+GL + LT F F K S + ++ F E +D+ +++ ++++
Sbjct: 563 NGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTE--LDVCKQLYNEHMKQIECG 620
Query: 558 NPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEI-LDSDRGQEVKQKYLEVGRTMK 616
+ L KN P +G + W + + R++ F ++ + L + V QKY+E+ +
Sbjct: 621 HVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLD 680
Query: 617 EYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINE 676
++E R Y +W +++ + + L+ S+I + +NF P L ++ E
Sbjct: 681 QFESRIYNEWKSNVDEICEFNLNQPLVKFSAI----------NGLLCVNFDPKLVAVLRE 730
Query: 677 TKYLEQLGFT-VPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQ 735
KYL L +P+ A + + + L+Y + ++ Y+ L TL + E L++D +
Sbjct: 731 VKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELR 790
Query: 736 ELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINL 795
+ + L W G YI + A + E V + KN I +
Sbjct: 791 AIDEQLTAATTWLTWQDDCWG-YIERVRAATSELEHRVERTQKNVKVIQQTMR------- 842
Query: 796 FKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNT--GK 853
+ LP +E D + Y I K+ LV
Sbjct: 843 -----GWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKA 897
Query: 854 APKLAS---YYKYWEKKIYEVLTKLILKNLQSF---NSLILGNVPLFHTETILTAPEIIL 907
P L + Y ++ + + E + I+ +L F L P F + IL PEI+
Sbjct: 898 NPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVF 957
Query: 908 HPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGE-EEEVVIINFYNDISLNP 966
P+ + R + V M + Q + I N+ ND+
Sbjct: 958 KPSLD----------REAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNML 1007
Query: 967 QIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAA------------- 1013
+ E I V ++ ++ + + + LW D+A M+ F
Sbjct: 1008 GLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAH 1067
Query: 1014 ------KKPPCVA-YDEKLQFYSKIAYEVMRHPLIKD-EHCIRLQLRHLANTVQENAKSW 1065
++PP + + E++ Y + ++ + + + ++ ++ ++ K W
Sbjct: 1068 ANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKW 1127
Query: 1066 VISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNT--LEDLKFVLATIAEIRSKSLVME 1123
+ L + L L E ++ L++ N + L ++ + +RS+ +
Sbjct: 1128 SWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATD 1187
Query: 1124 LRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELT 1183
+ ++E + Y P+ ++++ W + V H + + L
Sbjct: 1188 ELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLI 1247
Query: 1184 RGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKL 1243
R + + + + EF +RF P +G + + L EL E+ ++ + +L
Sbjct: 1248 RKKCILFDAKQAEFRERFRHYAP--LGFNAENPYTALDKANEELEALEEEMLQMQESTRL 1305
Query: 1244 FDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLR 1303
F++ + Y ++ + +KE+ L+ ++++ ++ + + W++T W ++V+ + + F +
Sbjct: 1306 FEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAK 1365
Query: 1304 A-----LRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVF 1358
A + L + VR LE +K S+ + +L++ ALRDRHW +LM+ V
Sbjct: 1366 ASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVK 1425
Query: 1359 FEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTV-VKYC 1417
F + E TL ++ A+ LH+ D + IV A+KE+ EK + EI TW MKF+ V Y
Sbjct: 1426 FLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYR 1485
Query: 1418 KGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIW 1477
G +L S +++ ++L+ N LQ++ S++V F++ V W+ L++ VI W
Sbjct: 1486 TGIP----LLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTW 1541
Query: 1478 MLVQRKWMYLESIFI-GGDIRSQLPEEAKKFDNIDKVFKRIMGETLK-DPVIKRCCEAPN 1535
M VQR W +LESIF+ DIR QL ++A++FD +D FK +M +T K + V++ C PN
Sbjct: 1542 MEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCR-PN 1600
Query: 1536 RLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGS-SDPLCVQEHMIK 1594
L+++ L C+K+L +YL++KR AFPRF+F+S +LL IL + P V H+ K
Sbjct: 1601 LYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAK 1660
Query: 1595 MYDNIASLRFNDG-DSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNR 1653
++D+IA L+F D D M S E E + F+ G VE W+ + M+ T R
Sbjct: 1661 LFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVR 1720
Query: 1654 LITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGR 1713
EAI Y E++ R W+ + V L +SQ+WWT +V F + ++G + A+K++ +
Sbjct: 1721 HSITEAIVAY-EEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHK 1779
Query: 1714 KMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFI--RGSILEAREFDWESQ 1771
K Q++ L+T + L DR+K T+ IDVHARD+V I + ++ + F W SQ
Sbjct: 1780 KQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQ 1839
Query: 1772 LRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPA 1831
LR W+ + C F Y YEY+G + RLVITPLTDR Y+TLTQ+L + + GAPA
Sbjct: 1840 LRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPA 1899
Query: 1832 GPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDA 1891
GPAGTGKTETTKDL +ALG++ V NC E MDY+++G I+ GL Q GAWGCFDEFNRI
Sbjct: 1900 GPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISV 1959
Query: 1892 SVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKAL 1951
VLSV++ Q++ I +A+ ++ F F G+ I+L +GIFITMNPGYAGRTELPE++KAL
Sbjct: 1960 EVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKAL 2019
Query: 1952 FRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKS 2011
FRP ++ PD++ ICEI+L +EGF++A+ LA+K LY L +E LSKQ HYD+GLRA+KS
Sbjct: 2020 FRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKS 2079
Query: 2012 VLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYP 2071
VLV+AG LKRG + ED VLMRALRD N+PK V +D+P+FLGL+ DLFP LD PR R
Sbjct: 2080 VLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKL 2139
Query: 2072 DFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQT 2131
F V Q E + KVVQ+ E + RH+ VVG GKS ++ TL +
Sbjct: 2140 HFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYV 2199
Query: 2132 KLGLTTKLYILNPKAVSVIELYGILDPTTRDWTD---------GVLSNIFRE-INKPTDK 2181
+ LNPKAV+ EL+G + TR+W D G+ S+I RE N D
Sbjct: 2200 NMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDG 2259
Query: 2182 KERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPAT 2241
K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L LLFE+ L+ A+PAT
Sbjct: 2260 P--KWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPAT 2317
Query: 2242 VSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQ 2301
VSR G++YV+P++L + PY W+++ ++ E+ NL LF+KYVP +D + R
Sbjct: 2318 VSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKL-------RT 2370
Query: 2302 AEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LLECYFLEALYCSLGASLLED 2357
+ K T +P++ L V L +L+ LL E D + E YF+ A + G +LL+D
Sbjct: 2371 SFKTITSIPESSL--VQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQD 2428
Query: 2358 GRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYI 2417
+ +Y + + + V + P Q T++D++ D+K + +PW+ + ++
Sbjct: 2429 ---QISDYQADFSRWWQKEMKAV-----KFPSQ-GTIFDYYVDHKTKKLLPWADKIAQFT 2479
Query: 2418 HAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETN 2477
P+ +LVHT +T R + +E +++ +P++ VG +G KT + L +LSE+
Sbjct: 2480 MDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-Y 2538
Query: 2478 IVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQP 2537
IV V F+ TTS +Q+ LE +EK+ YGP K+L+ F+DDMNMP VD YGT QP
Sbjct: 2539 IVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQP 2598
Query: 2538 IALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNVPFP 2597
L++ ++ G+ YDR K + K I + ++A M G ++PR F+VF FP
Sbjct: 2599 HTLIRQHIDYGHWYDRQKVM-LKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFP 2656
Query: 2598 SEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFN 2655
S ++L+ IY I H F SI+ L T+A ++ ++ + PT KFHYIFN
Sbjct: 2657 SLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFN 2716
Query: 2656 LRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVE 2715
LRDLS VF G++ +PE + ++ +W +E RV+ D+LI + D L Q+ + +
Sbjct: 2717 LRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYK 2776
Query: 2716 HFKD-DVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMN 2774
+F+ D ++++ P+++ F G+ Y ++D+E K + E L+ YNE N M+
Sbjct: 2777 YFEGIDSHMLLQQPLIYCHF---ADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMH 2833
Query: 2775 LVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYS 2834
LVLF+DA++H+ R+ RI+R +G ALLVGVGGSGKQSLSRLAA+ EVF+I L+ GY
Sbjct: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
Query: 2835 ENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKES 2894
R DL +LY++ G +N +FL TDA V +E FL LIN++L SG +P LFS+E+ +
Sbjct: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
Query: 2895 ILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNT 2954
I+S I E GM ++E+ W++F+ + L I+L SPVG TLR R FP +VN T
Sbjct: 2954 IISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013
Query: 2955 GIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRS 3014
IDWF WP +AL +V++ F+ I + +++ + VH +V+ S ++ Q RR
Sbjct: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRH 3073
Query: 3015 NYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIV 3074
NY TPK++L+ I+ + LL +K + +RL G+ KLK Q+ +L +LA Q+
Sbjct: 3074 NYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAE 3133
Query: 3075 LAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPI 3134
L ++ EAL+ +I + T +K +A+ + ++ + ++ E E L + P
Sbjct: 3134 LQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193
Query: 3135 LEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIM-----KGYKELNWKTAKGVMS 3189
L AA L L++ +++E+++F PP V V ++++ + K+ +WK AK M
Sbjct: 3194 LVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMG 3253
Query: 3190 D-PNFLRSLMEIDFDSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGY 3247
+FL++L+ D + I ++ +K + + LK + S A G+ +V ++ +
Sbjct: 3254 KVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKF 3313
Query: 3248 CDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQ 3307
+V+ +++PKR+ +A+ +LE I+ +L + + L L A +E A EK + Q
Sbjct: 3314 YEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQ 3373
Query: 3308 EEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTW 3367
EE + + A++L+ L ++ IRW + + L GD LL AAF+SY G FT
Sbjct: 3374 EEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTR 3433
Query: 3368 EFRDEMVNRIWQNDILER-EIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILT 3426
++R E+V+ W + ++ IPL++ L S+LTDD I+ W ++GLP D +S +N +
Sbjct: 3434 QYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAIL 3493
Query: 3427 TRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDE 3486
T R+PL IDPQQQ + WIK K +L+V FL +E ++ +G L +++E
Sbjct: 3494 THCERWPLVIDPQQQGIKWIKNKYGM-DLKVTHLGQKGFLNAIETALAFGDVILIENLEE 3552
Query: 3487 YIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVI 3546
IDPV+D +L +N + +G+ +I +GDKE +++ NFRL L+TKLANP Y P + + ++
Sbjct: 3553 TIDPVLDPLLGRN-TIKKGK-YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLL 3610
Query: 3547 NYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGN 3606
N+TVT GLE QLL+ +V+ ER +LE+ + L + ++ K LK LED LL L+ + G+
Sbjct: 3611 NFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGS 3670
Query: 3607 MLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMA 3666
LD+ LV LE TK+ E+ K+ A++ I+ R+ YRP A R ++L+FV++++
Sbjct: 3671 FLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQ 3730
Query: 3667 LVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLL 3726
+N +YQ+SL AF +F +++++ + R+ +M+++T +++ + LFE+ KL
Sbjct: 3731 KINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLT 3790
Query: 3727 FSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSD 3786
F M +I + + ELDF L+ + + P +L+ Q W I ++ M +
Sbjct: 3791 FLSQMAFQILLRKKEIDPLELDFLLRFTV---EHTHLSPVDFLTSQSWSAIKAIAVM--E 3845
Query: 3787 NFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVT 3846
F + DVE + W++W + + E+ +P + + QKL++LR R DR+ A+
Sbjct: 3846 EFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALR 3904
Query: 3847 DYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRL 3906
++V +G KYV+ + FE+S+P +PI FILSPG D DL L +R GF +
Sbjct: 3905 NFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSG 3964
Query: 3907 KF--LAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITK-PHPDFR 3963
KF +++GQGQE VA LE A G W++LQN HL+ KWL LEK LER ++ H D+R
Sbjct: 3965 KFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYR 4024
Query: 3964 LWLTTD--PTKG---FPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQC-PHPAF 4017
++++ + PT P G+L+ S+K+ EPP G+ N+ A + + L+ C F
Sbjct: 4025 VFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEF 4084
Query: 4018 KPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPW 4077
K +++ L +FHA V R +FG GW+ Y FN D +C +L YL + + ++PW
Sbjct: 4085 KSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL-----EANSKVPW 4139
Query: 4078 GSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGD 4137
L+YL GE+MYGG D +DR++ +Y++E++ + + + P
Sbjct: 4140 EDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELML------APGFAAPPYL 4193
Query: 4138 EKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSS--GIS 4195
+ + + IE + +P ++GLHPNAEI + T + ++ LLE+QP+ S G S
Sbjct: 4194 DYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQS 4253
Query: 4196 RDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAE 4255
++ + V +I K+P+ F++ ++ ++ + SP +V QE ER N L+ + SL +
Sbjct: 4254 TEEKVKNVLDDILEKLPEEFNMAEIMQK-NSNRSPYVLVCFQECERMNILIREIRISLEQ 4312
Query: 4256 LQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWV 4315
L +L GE+ +S ++ +L +P+ W +LA + L W L R + W
Sbjct: 4313 LDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT 4372
Query: 4316 TE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQ 4374
+ + P+V+WLSG P+S+LTA++Q RKN WPLD++ L VTK + ++ +
Sbjct: 4373 QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTK-KTKEDYGHPPRE 4431
Query: 4375 GCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTS 4434
G ++ GL++EGA WD + G +++++ K L +P++ R + + T+ PVY T
Sbjct: 4432 GAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTK 4491
Query: 4435 MRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTLNS 4470
+R G ++ L + + WVL GV L L +
Sbjct: 4492 LR----GPSYIWTFRLKSEEKTAKWVLAGVALLLEA 4523
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2093 bits (5424), Expect = 0.0
Identities = 1236/3607 (34%), Positives = 1978/3607 (54%), Gaps = 177/3607 (4%)
Query: 966 PQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAA--------KKPP 1017
P + E I V + +I L Y +++++Y L D A ++ + ++
Sbjct: 724 PLVEELRATIASAVSKAMIPLQAYAKEYRKYLELNNNDIASFLKTYQTQGLLAQEVREVV 783
Query: 1018 CVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESA 1077
EK S + ++ P + ++ ++ + K+ S+ +L ++
Sbjct: 784 LTHLREKEILDSSLPSSIIIGPFY-------INTDNVKQSLSKKRKALATSVLDILAKNL 836
Query: 1078 KEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMA 1137
+E+ ++ EE +++ + + PN++E+L + + I + + +E R V + Y+ M
Sbjct: 837 HKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLVGLEERIVKVMDDYQVMD 896
Query: 1138 --MYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1195
+YNL D + I S W + LG I+ + E ++QI
Sbjct: 897 EFLYNLSSDDFNDKW---IASNWPSKI---------LGQIELVQQQHVEDEEKFRKIQIM 944
Query: 1196 E---FAKRFYSEGPGSVGDDLDKGVELLGVYE-----RELARHEKSRQELA----NAEKL 1243
+ F ++ EG V VE+ +E R + + K Q+LA N E++
Sbjct: 945 DQNNFQEKL--EGLQLVVAGFSIHVEISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERI 1002
Query: 1244 FDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLR 1303
F LPIT Y +L ++ KE ++ E W ++ + L++ + +
Sbjct: 1003 FSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFK 1062
Query: 1304 ALRKLPRPVRGL----SVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFF 1359
+ K + + + V + A+++ FK IPL+ L+N +R RHW+ L + ++
Sbjct: 1063 TMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININV 1122
Query: 1360 EMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKG 1419
T M L H + ++++ A KE AIE+A+ ++ W + F V+ Y K
Sbjct: 1123 RPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPY-KA 1181
Query: 1420 TQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWML 1479
T YIL S DE Q LDD+ Q++S S + PF Q ++ WE L L EV+E W+
Sbjct: 1182 TDT--YILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLN 1239
Query: 1480 VQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSD 1539
QR W+YLE IF DI QLP E+K++ +++++K+IM ++ + C L
Sbjct: 1240 CQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDS 1299
Query: 1540 LQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDN 1598
L++ ++ L+ QK L++YL++KR+AFPRF+F+SDDELL IL + DP VQ H+ K ++N
Sbjct: 1300 LRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFEN 1359
Query: 1599 IASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKE 1658
IA L F + + ++ M SAEGE ++ + VEDW+ V M+ + I ++
Sbjct: 1360 IARLLFQE----DLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEK 1415
Query: 1659 AIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQ 1718
AI Y R W+L + G V +A Q +WT EV + ++ +Q
Sbjct: 1416 AIRAY-PTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAGN-----LRSQLFPQLCQQ 1469
Query: 1719 IDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDR 1778
+ +LV + LS+ R + +++I+VHA+D+V I+ +++ +F W SQLR+YW
Sbjct: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
Query: 1779 EPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGK 1838
++L IR F YGYEY+G +GRLVITPLTDR YLTLT AL + GGAPAGPAGTGK
Sbjct: 1530 --NDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
Query: 1839 TETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVIS 1898
TETTKDL KAL + VV NC + +D+ A+GK F GLA GAW CFDEFNRID VLSV++
Sbjct: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
Query: 1899 SQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVI 1958
QI TI+ A ++ F FEG EI L +FITMNPGYAGRTELP+++KALFRPV ++
Sbjct: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
Query: 1959 VPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGE 2018
VPD I EI L+S GF EA LAKK+T +KL+ EQLS Q HYDFG+RA+K+V+ AG
Sbjct: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
Query: 2019 LKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVE 2078
LKR + + E+++ +RA+RD+N+PKF+ ED+ LF G++SDLFP + Y ++A+
Sbjct: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIR 1827
Query: 2079 QVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKL----- 2133
+ + + + K +Q++ET + RH M+VGPT GKS L A T L
Sbjct: 1828 EACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPS 1887
Query: 2134 ---GL--TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYIL 2188
G+ Y+LNPK++++ +LYG D T +WTDG+ S+ R T +K+ +
Sbjct: 1888 ISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIR-AGAITSDTNKKWYM 1946
Query: 2189 FDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMV 2248
FDG VDA+W+ENMN+V+DDN+ L L++GE I+L ++FEV DL ASPATVSRCGMV
Sbjct: 1947 FDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMV 2006
Query: 2249 YVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTI 2308
Y++P L P+ + W+ ++P ++ Y E + + + E I R + +K +
Sbjct: 2007 YLEPSILGLMPFIECWLRKLPPLLKPYE-----EHFKALFVSFLEESISFVRSS--VKEV 2059
Query: 2309 VPQTDLNMVTQLAKMLDALL--------------EGEIEDLDLLECYFLEALYCSLGASL 2354
+ T+ N+ L K+LD E ++L+E +F+ +L S+GA+
Sbjct: 2060 IASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATG 2119
Query: 2355 LEDGRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDN------------- 2401
GR F +++ L + + P E ++D+ ++
Sbjct: 2120 DSSGRTSFSHWLR----LKMENEQLTLLFPEE-----GLVFDYRLEDAGISGTNDSEDEE 2170
Query: 2402 ---KRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESG 2458
K+ WV W + P+ + NI+V T+DT + + +L+ ++ K+PV+ +G +G
Sbjct: 2171 EEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTG 2230
Query: 2459 TSKTAT-TQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRL 2517
T KT T + LKNL+ + I + FS+RT++ Q +++ ++KR K +GPP+G+
Sbjct: 2231 TGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNF 2289
Query: 2518 LVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGG 2577
+ F+DD+NMP ++ YG Q PI LL+ ++ G YDR K++ D+ F+ AMG GGG
Sbjct: 2290 IFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGG 2349
Query: 2578 RNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKG------HTSTFHE------SIVAVS 2625
RN V PR + F+ + E S I+S+IL ++ E I +
Sbjct: 2350 RNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFT 2409
Query: 2626 GKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWR 2685
L T+ +Y I L PTP+K HY FNLRDLS+VF G+++ +P + + Q++R+W
Sbjct: 2410 EPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWY 2469
Query: 2686 NECLRVFHDRLISETDKQLVQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRI 2745
+E RVF DRL++E D+ Q + + + +V PIL+GDF + +
Sbjct: 2470 HENCRVFRDRLVNEEDRSWFDQLLKRCMEQWEVTFNKVCPFQPILYGDFMSP--GSDVKS 2527
Query: 2746 YEDIQDYEAAKALFQEILEEYNESNT-KMNLVLFDDALEHLTRVHRIIRMDRGHALLVGV 2804
YE I + +E +E+YN+ NT K+ LVLF DA+ H+ R+ R +R G+ALL+GV
Sbjct: 2528 YELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGV 2587
Query: 2805 GGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAH 2864
GGSG+ SL+RLA+ A E F+I LS+ Y + +R+D+K + LK G++N + FLF+D
Sbjct: 2588 GGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQ 2647
Query: 2865 VAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSA 2924
+ E FLE INN+L SG +P L++ +E++ I+S + +QG+ P K ++ + +
Sbjct: 2648 IKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVR 2707
Query: 2925 NNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPA- 2983
+N+H+VL MSP+G+ R R FP +VN IDWF WP +AL +VA FL P + +
Sbjct: 2708 SNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESS 2767
Query: 2984 -ENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIA 3042
E I+ +++ V +HQSV ++L +L R NYVTPK+YL+ ++ +S L+ +K
Sbjct: 2768 QEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKT 2827
Query: 3043 QCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKL 3102
R+ GLDKL + + ++ + L +L E + +E+I V+TA+AEE +
Sbjct: 2828 AKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNS 2887
Query: 3103 AEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQ 3162
+ + ++ E+ K +A+ L E +P L+AA L+ L+K+DVTE+R+ +PP
Sbjct: 2888 VQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPG 2947
Query: 3163 VQTVCECILIMKGYKELN-------------WKTAKGVMSDP-NFLRSLMEIDFDSITQS 3208
V+ V E + IMKG K W+ KG++ DP +FL SL + D D+I
Sbjct: 2948 VKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDV 3007
Query: 3209 QVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNF 3268
+K I+ + + VSKA + ++V A+ Y V + ++PKR+ + + +
Sbjct: 3008 VIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDL 3067
Query: 3269 YLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLG 3328
+T+R L+ + L ++ + T+ AKY I +K++L+ + E E+RL A KLI+GL
Sbjct: 3068 GVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLINGLS 3127
Query: 3329 SENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIP 3388
E +RW ++ L + + GD L+ A F++Y G FT ++R + + W + +P
Sbjct: 3128 DEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDS-WVKQLRSHNVP 3186
Query: 3389 LSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKR 3448
+ L L + V+I W GLP D LSV+NG++ + R+ IDPQ QA WIK
Sbjct: 3187 HTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKN 3246
Query: 3449 KEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQF 3508
E+ N L V +D DFL+ +E +I++G P L +V E +DP ++ VL K QG
Sbjct: 3247 MEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTV 3306
Query: 3509 IILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYER 3568
+ LGD + Y +FR+Y+ TKL NP Y+P + K +IN+T++ GLEDQLL +VA ER
Sbjct: 3307 LKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEER 3366
Query: 3569 RELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVS 3628
+LEE + LI ++ + LKD+ED +L L++S GN +D+++L+ LE +K KA E+
Sbjct: 3367 PDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQ 3426
Query: 3629 EKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLK 3688
K+++AE+T DID R Y P A R ILFF +S++A V+ MYQYSL FL +F +
Sbjct: 3427 AKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIA 3486
Query: 3689 KSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELD 3748
S L KR+ NI LT+S+Y++ C LFE+HKL+F+F + ++I EG++ Q E
Sbjct: 3487 NSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWR 3546
Query: 3749 FFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDL 3808
+ L G ++ P WLSD+ W DI+ LS + F D + + ++ +D
Sbjct: 3547 YLLSGGSISIMTENPAP-DWLSDRAWRDILALSNL--PTFSSFSSDFVKHLSEFRVIFDS 3603
Query: 3809 DSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAI 3868
+ P+P +D + FQKLL+LRC R D+V A+ D+V + ++++P + +
Sbjct: 3604 LEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVV 3663
Query: 3869 FEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVA 3928
F+ S +P++F+LSPG+DPA DL K AE F +L +++GQGQ A ++ +++
Sbjct: 3664 FKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRAEAMMRSSIE 3722
Query: 3929 RGQWLMLQNCHLLVKWLKDLEKSLERIT--KPHPDFRLWLTTDPTKGFPIGILQKSLKVV 3986
RG+W+ QNCHL W+ LE+ +E I K H DFRLWLT+ P+ FP+ ILQ K+
Sbjct: 3723 RGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMT 3782
Query: 3987 TEPPNGLKLNMRATYFKISHEMLDQCPH-PAFKPLVYVLAFFHAVVQERRKFGKIGWNVY 4045
EPP G++ N+ +Y + + L+ C FK L+ L FH ERRKFG +G+N+
Sbjct: 3783 IEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIP 3842
Query: 4046 YDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIY 4105
Y+F + D ++C+ L K F IP+ LKY GE+ YGGR D +DRR +
Sbjct: 3843 YEFTDGDLRICISQL-----KMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNI 3897
Query: 4106 MDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAE 4165
++++ D P H + + ++IP + ++ I++LPL + PE+FGLH NA
Sbjct: 3898 LEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 3954
Query: 4166 IGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLG 4225
I + + +++LQP++ + S R++ + V + I K+P+ +L V +
Sbjct: 3955 ITFAQNETFALLGTIIQLQPKSSSAGSQ-GREEIVEDVTQNILLKVPEPINLQWVMAKYP 4013
Query: 4226 TGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPN 4284
+ + VL+QE+ R+N+L+ +T++L +L +AL G V MS++L+ +A SL+ +P
Sbjct: 4014 VLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPE 4073
Query: 4285 IWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCR 4344
+W A +LK L +W++ L+R W+ + P+V W+SG P+++LT +Q R
Sbjct: 4074 LWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFAR 4133
Query: 4345 KNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLV 4404
K +D + F F+ E+ +R GC++ GL+LEGA WD E L +S+PK L
Sbjct: 4134 KFVISID-TISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELY 4192
Query: 4405 VDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTTRHISHW 4459
++ ++ ++P + + Q+ + P+Y T R + V ++ T + HW
Sbjct: 4193 TEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHW 4252
Query: 4460 VLQGVCL 4466
+ +GV L
Sbjct: 4253 IKRGVAL 4259
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 2056 bits (5328), Expect = 0.0
Identities = 1239/3557 (34%), Positives = 1961/3557 (55%), Gaps = 175/3557 (4%)
Query: 1028 YSKIAYEVMRHPLIKDE------HCIRLQL--RHLANTVQENAKSWVISLGKLLNESAKE 1079
Y KI E+ ++ + +E IRL + H ++ K I GKLL + ++
Sbjct: 519 YEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRD 578
Query: 1080 ELY---NLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLV-MELRYRDVQERYRT 1135
L +E E +A+ P +L + A I ++ ++ +E R D +
Sbjct: 579 HQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAF 638
Query: 1136 MAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIE 1195
+ Y F P A+ L + + + + + + + E + + ++E
Sbjct: 639 LIEYVNFSP-ADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELE 697
Query: 1196 EFAKRFYSEGPGSVGD--DLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPE 1253
+AK+ SE S GD D+ + ++ + +L ++ E+ F ++YP+
Sbjct: 698 SYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQ 755
Query: 1254 LLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVR 1313
K+Q ++ +YE W++ + +N ++ I + R L KL +
Sbjct: 756 RKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFH 815
Query: 1314 ----GLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLEN 1369
L++T + +K++ FK IPL+ + N LR RHW+ + + ++ T+ +
Sbjct: 816 DSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSS 875
Query: 1370 MFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERG-YILG 1428
M L + D I AA KE ++EKA+++++ W+ ++F + Y +E G +IL
Sbjct: 876 FLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSY----RETGTFILA 931
Query: 1429 SVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLE 1488
SVDEI LDD+ Q++ GS F+ P+ + + +WE L L+ E+++ W+ VQ W+YLE
Sbjct: 932 SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 991
Query: 1489 SIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLE 1548
IF DI SQ+PEE ++F +DK ++ IM ++D + L L+ +E LE
Sbjct: 992 PIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1051
Query: 1549 KCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDNIASLRFNDG 1607
K LN+YL+ KR FPRFFF+S+DELL IL + DP VQ H+ K ++ IA + F +
Sbjct: 1052 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1111
Query: 1608 DSGEKLVSAMISAEGEVMEFRKIL---RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYC 1664
++ M S+EGEV+E +I+ +A G+VE W+ + M + +T +A F Y
Sbjct: 1112 LD----ITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYT 1167
Query: 1665 EDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVT 1724
+ R++W+ + G VL SQ++WT EV+ K A++ Y + +RQID++VT
Sbjct: 1168 K-YERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK----ALEQYLKTCNRQIDDIVT 1222
Query: 1725 RITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELN 1784
+ LS +R ++++DVHARD++ S ++ +I + +F+W SQLR+YW + + L
Sbjct: 1223 LVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW--QENHLE 1280
Query: 1785 IRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKD 1844
+ YGYEY+G + RLVITPLTDR Y TL AL ++LGGAP GPAGTGKTETTKD
Sbjct: 1281 TKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKD 1340
Query: 1845 LAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTI 1904
LAKA+ CVV NC +G+DY A+GK F GL CGAW CFDEFNRID VLSV++ QI TI
Sbjct: 1341 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTI 1400
Query: 1905 RNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQ 1964
+ + FEG E+ LD +FITMNPGYAGR+ELP+++KALFR V ++VPD
Sbjct: 1401 QRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAM 1460
Query: 1965 ICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSS 2024
I EI+L+S GF+ A+ L+ K+ Y+L EQLS Q+HYD+G+RA+KSVL AG LK
Sbjct: 1461 IAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYP 1520
Query: 2025 DLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEEN 2084
+ E+++L+R++ D+NLPKF+ D+PLF G+ SDLFPG+ P+ PD+ND + + ++
Sbjct: 1521 NENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFPGVKLPK---PDYNDLLAAI--KD 1575
Query: 2085 GYAVLPIQV-----DKVVQMFETMLTRHTTMVVGPTRGGKSV-------VINTLCQAQTK 2132
A + +Q+ +K++Q++E M+ RH M+VG GGK+ +N +C+
Sbjct: 1576 NCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTSAYRVLAGALNDICEKGLM 1635
Query: 2133 LGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGD 2192
++ +LNPK+V++ +LYG D + +W+DGVL+ FR +RK+++FDG
Sbjct: 1636 EENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRAFASSV-TPDRKWLIFDGP 1694
Query: 2193 VDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDP 2252
VDA+W+ENMN+V+DDN+ L L +GE I++ L+FE DL+ ASPATVSRCGM+Y++P
Sbjct: 1695 VDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEP 1754
Query: 2253 KNLKYRPYWKKWVNQIP---NKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIV 2309
L +RP WVN +P + +++ + LF++ VP ++ I + K +
Sbjct: 1755 HMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI---------RKHTKELS 1805
Query: 2310 PQTDLNMVTQLAKMLDALLE-----------GEIEDLDLLECYFLEALYCSLGASLLEDG 2358
P +D N+V L ++D ++ + E LLE FL +L S+GAS +D
Sbjct: 1806 PTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIFLFSLIWSVGASCTDDD 1865
Query: 2359 RMKFDEYIKRLASLSTVD-----------TEGVWANPGELP-GQLPTLYDFHFDNKR-NQ 2405
R+KF++ ++ L D TE + +P + T+YD+ F + +
Sbjct: 1866 RLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIYDYQFVTEGIGK 1925
Query: 2406 WVPWSKLVPEYIHAPERKFIN-ILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTAT 2464
W PW K + E P+ N I+V T+DT R + ++E + ++P IFVG +GT K+
Sbjct: 1926 WEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVY 1985
Query: 2465 TQNFLKN-LSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDD 2523
NFL N L++E L++NFS++TT+ Q + + ++KR K +GPP+GKR++VF+DD
Sbjct: 1986 ITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPPLGKRMVVFVDD 2045
Query: 2524 MNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDP 2583
+NMP + YG Q PI LL+ L+ YD K+ + + D+ + AMG GGGRN V P
Sbjct: 2046 VNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKLVDIQIMCAMGPPGGGRNPVTP 2104
Query: 2584 RFISLFSVFNVPFPSEESLHLIYSSILKGHTS---TFHESIVAVSGKLTFCTLALYKNIV 2640
R++ F++ + S++S++ I+S IL H F + + ++ ++ T+ LYK +
Sbjct: 2105 RYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVNGTMTLYKEAM 2164
Query: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700
++L PTP+K HY+FNLRD SRV G+ L+ PE +T + R+W +E LRV++DRL+ T
Sbjct: 2165 KNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNT 2224
Query: 2701 DKQLVQQHIGSLVVEHFKDD---------------VEVVMRDPILFGDFQMALHEGEPRI 2745
D+ + +I ++ + +D VE ++F DF + E
Sbjct: 2225 DRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFHDP--KREDTN 2282
Query: 2746 YEDIQDYEAAKALFQEILEEYNESNTK-MNLVLFDDALEHLTRVHRIIRMDRGHALLVGV 2804
Y +I D + + + + LEEYN + K MNLVLF A+EH++R+ RI++ R HALLVGV
Sbjct: 2283 YREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGV 2342
Query: 2805 GGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAH 2864
GGSG+QS++RLAA A VF++ +S+GY + EDLK + K +FLFTD
Sbjct: 2343 GGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQ 2402
Query: 2865 VAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQ-----EALKQGMGPAKESVWQYF 2919
+ EE FLE ++N+L +G +P LF+ +EK+ I ++ Q + KQ G + +++ F
Sbjct: 2403 IKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDG-SPIALFNMF 2461
Query: 2920 VNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNP 2979
++ + LH+VL MSP+GD R R FP +VN IDWF WP AL AVA FL
Sbjct: 2462 IDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE 2521
Query: 2980 MIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQC 3039
M E + + H S S+ F +L+R NYVTP +YL+ I+T+ LL++K
Sbjct: 2522 M-SEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSE 2580
Query: 3040 NIAQCKRLDGGLDKLKEATIQLDELNQKLA---EQKIVLAEKSAACEALLEEIAVNTAVA 3096
+ KR + GL+KL A+ Q+ + +L Q V +++ ++E+ +V A
Sbjct: 2581 VMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKT 2640
Query: 3097 EEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156
E+ K E A E +K I K E + LA +PILE+A L L D+T ++S
Sbjct: 2641 EKIVKADETIANEQAMASKAI---KDECDADLAGALPILESALAALDTLTAQDITVVKSM 2697
Query: 3157 AKPPKQVQTVCECILIMKGYK--------------ELNWKTAKGVMSDPNFLRSLMEIDF 3202
PP V+ V E I I+KG K E W AK ++ D FL+SL E D
Sbjct: 2698 KSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDK 2757
Query: 3203 DSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKV 3261
D+I + + I K + + E++ S A G+ K+V A+ Y V + + PK+ K+
Sbjct: 2758 DNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKL 2817
Query: 3262 ARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAAD 3321
A E + L + Q L +Q +L L E +K L+ + ++ ++L A+
Sbjct: 2818 AAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAE 2877
Query: 3322 KLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQND 3381
+LI GLG E RW + EL + L GD L+ + ++Y GAFT +R W
Sbjct: 2878 QLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKE-WTTL 2936
Query: 3382 ILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQ 3441
R+IP S L L + V I W GLP D S+ NGI+ A R+PL IDPQ Q
Sbjct: 2937 CKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQ 2996
Query: 3442 ALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIK 3501
A WIK E+ N+L V ++PD+++ LE I++GTP L +V E +DP+++ +L K
Sbjct: 2997 ANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTF 3056
Query: 3502 VSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLS 3561
G I LGD ++Y +FR Y+ TKL NP Y P K ++N+ +T +G++DQLL
Sbjct: 3057 KQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLG 3116
Query: 3562 VLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETK 3621
++VA ER +LEE+++ LI + +ENK LK++ED +L L++S GN+L++ + L +K
Sbjct: 3117 IVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSK 3176
Query: 3622 SKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLE 3681
+ A E+S+K ++AE+T ID R GYRP A +ILFF L+++A + MYQYSL F+
Sbjct: 3177 ALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFIN 3236
Query: 3682 VFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGR 3741
+F LS++ S IL KRL+ + D T+S+Y + C LFE+ KLLFSF +TI + E
Sbjct: 3237 LFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERA 3296
Query: 3742 VPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTV 3801
+ + E F L G I L+ + C WL + W++I L ++ F + + +
Sbjct: 3297 INKAEWRFLLTGGIGLD-NPYANLCTWLPQKSWDEICRLDDL--PAFKTIRREFMRLKDG 3353
Query: 3802 WQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPP 3861
W++ YD P +++ FQ++LI+RC R D+V + +++ +G +++PP
Sbjct: 3354 WKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPP 3413
Query: 3862 MISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQ 3921
F S +P++F+LSPG+DP L+K A+ G+GG++L L++GQGQ +A++
Sbjct: 3414 PFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMK 3473
Query: 3922 LLETAVARGQWLMLQNCHLLVKWLKDLEKSLERIT--KPHPDFRLWLTTDPTKGFPIGIL 3979
+LE AV G W++LQNCHL W+ LEK E ++ HPDFR+WLT+ P+ FP+ +L
Sbjct: 3474 MLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVL 3533
Query: 3980 QKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCPHP-AFKPLVYVLAFFHAVVQERR 4035
Q +K+ E P GL+ N+ +Y E C P FK L+Y L FFHA+VQERR
Sbjct: 3534 QNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQERR 3593
Query: 4036 KFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAID 4095
KFG +GWN+ Y+FNE+D ++ ++ L+ +L + +P+ +L+Y+ GE YGGR D
Sbjct: 3594 KFGPLGWNIPYEFNETDLRISVQQLHMFLNQY-----EELPYEALRYMTGECNYGGRVTD 3648
Query: 4096 SFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTP 4155
+DRR L ++++ + + + F + + + P GD K ++E + LPL P
Sbjct: 3649 DWDRRTLRSILNKFFNPELVENSD--YKFDSSGIYFVPPSGDHK-SYIEYTKTLPLTPAP 3705
Query: 4156 EVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVF 4215
E+FG++ NA+I + ++ ++L Q ++ + S D+ + +VA +I K+P F
Sbjct: 3706 EIFGMNANADITKDQSETQLLFDNILLTQSRSA-GAGAKSSDEVVNEVASDILGKLPNNF 3764
Query: 4216 DLDQVRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVA 4274
D++ +R T + + + VL+QE+ RFNKL+ + S +Q+A+ G MS +L++V
Sbjct: 3765 DIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVV 3824
Query: 4275 RSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESY 4334
S+ IP +W + +LK LG+++ FL R W P V WLSG +++
Sbjct: 3825 SSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAF 3884
Query: 4335 LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGC 4394
LT Q RK P+D +V + E G F+ GL+L+GA W+ +
Sbjct: 3885 LTGAQQNYARKYTIPIDLLGFDYEV---MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKK 3941
Query: 4395 LIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEAD 4449
L +S PK+L +P++ + P + + + ++ P+Y TS RR + V
Sbjct: 3942 LAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMT 4001
Query: 4450 LFTTRHISHWVLQGVCL 4466
L + + HW+ +GV L
Sbjct: 4002 LPSDQPKEHWIGRGVAL 4018
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 2012 bits (5212), Expect = 0.0
Identities = 1223/3491 (35%), Positives = 1902/3491 (54%), Gaps = 148/3491 (4%)
Query: 1060 ENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKS 1119
+N K +I +N + N + H+A + ++P ++L ++ + + S
Sbjct: 680 QNLKDHLIQFQVDVNRDTNTSICN---QYSHIADKVSEVPANTKELVSLIEFLKK-SSAV 735
Query: 1120 LVMELR--YRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNV-EHALGDIK 1176
V +LR RD ER + Y +L +IE I+ N N ++ + A D+
Sbjct: 736 TVFKLRRQLRDASERLEFLMDY--------ADLPYQIEDIFDNSRNLLLHKRDQAEMDLI 787
Query: 1177 RTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQE 1236
+ +E + Y ++E F KR +++ VE L + L R +
Sbjct: 788 KRCSEFEL-RLEGYHRELESFRKREVM-----TTEEMKHNVEKLNELSKNLNRAFAEFEL 841
Query: 1237 LANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQE 1296
+ E+L + + YP L + K ++ + EEW LN + + E
Sbjct: 842 INKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAE 901
Query: 1297 GIEGFLRALRKLPRPVRGLSVTYYL----EAKMKAFKDSIPLLLDLKNEALRDRHWKELM 1352
I R KL + + + L + K+ FK IP+L N ++DRHW+++
Sbjct: 902 EIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQIS 961
Query: 1353 EKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFT 1412
E + TET L NM K + L I AA KE ++EK + + W N+ F+
Sbjct: 962 EIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFS 1021
Query: 1413 VVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGE 1472
VKY + T IL ++D+I LDD+ Q++ GS F+ P KWE+ L I +
Sbjct: 1022 FVKY-RDTDTN--ILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQD 1078
Query: 1473 VIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCE 1532
++ W+ Q W+YLE IF DI +Q+PEE +KF +D +K +M + +KD I +
Sbjct: 1079 NLDAWLKCQATWLYLEPIFSSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAAD 1138
Query: 1533 APNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEH 1591
P LQ + LE QK LNDYL+ KR FPRFFF+S+DELL IL + DPL VQ H
Sbjct: 1139 QPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPH 1198
Query: 1592 MIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEF-RKIL--RAEGRVEDWMTAVLNEM 1648
+ K ++ IA L F D + MIS+E E + F +KI A+G VE W+ V M
Sbjct: 1199 LKKCFEGIAKLEFTDNLE----IVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMM 1254
Query: 1649 RRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAM 1708
+ R + I Y + R W+L + G VV+ S ++WT EV +Q + +
Sbjct: 1255 LASMREVIGLGIEAYVKV-PRNHWVLQWPGQVVICVSSIFWTQEV------SQALAENTL 1307
Query: 1709 KNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDW 1768
++ +K + QI ++V + LS R + +IDVHARD+V + + +F W
Sbjct: 1308 LDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQW 1367
Query: 1769 ESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGG 1828
SQLR+YW + ++ ++ T YGYEY+G + RLVITPLTDR Y TL AL + LGG
Sbjct: 1368 ISQLRYYWVAK--DVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGG 1425
Query: 1829 APAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNR 1888
AP GPAGTGKTETTKDLAKAL CVV NC +G+DY+A+GK F GLAQ GAW CFDEFNR
Sbjct: 1426 APEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNR 1485
Query: 1889 IDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESV 1948
I+ VLSV++ QI +I+ A+I +L TF FEG E+SL+ +FITMNPGYAGR ELP+++
Sbjct: 1486 IEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNL 1545
Query: 1949 KALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRA 2008
KALFR V ++VPD I EI L+S GFL++++LA+K+ Y+L EQLS Q+HYD+G+RA
Sbjct: 1546 KALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGMRA 1605
Query: 2009 LKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRV 2068
+KSVL AG LK + E V+L+RAL D+NL KF+ +DVPLF G+ISDLFPG+ P+
Sbjct: 1606 VKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLPKP 1665
Query: 2069 RYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQ 2128
Y F + +++ +P + K++Q++E ML RH M+VG GGK+ L
Sbjct: 1666 DYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVLAA 1725
Query: 2129 AQTKLGLTTKL-------YILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDK 2181
A L ++ I+NPKA+++ +LYG D + +W DGVL+N FRE +
Sbjct: 1726 ALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFRE-QASSLS 1784
Query: 2182 KERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPAT 2241
+RK+I+FDG VDA+W+ENMN+V+DDN+ L L +GE I++ + +L+FE DL+ ASPAT
Sbjct: 1785 DDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPAT 1844
Query: 2242 VSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQ 2301
VSRCGM+Y++P L ++P +++ +P+ + + + + + ++ + + G + +
Sbjct: 1845 VSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCKF 1904
Query: 2302 AEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDL------------LECYFLEALYCS 2349
+ I +M+ + +LD + E E+++L L+ FL +L +
Sbjct: 1905 VVQTSPI--HLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWT 1962
Query: 2350 LGASLLEDGRMKFDEYIKRLASLSTVD-----TEGVWANPGELPGQLPTLYDFHFDNKRN 2404
+ ++ D R KFD + + L + +D + V + + ++YDF+F + +
Sbjct: 1963 VAGTINADSRKKFDVFFRNL--IMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQAS 2020
Query: 2405 -QWVPWSK-LVPEYIHAPE-RKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSK 2461
W W++ + E P K +++ T++T R ++ L+ + + P++FVG +GT K
Sbjct: 2021 GHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGK 2080
Query: 2462 TATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFM 2521
+A T NFL +L + T + +NFS+RT++ Q + + +++R K +GPP+GK+ +VF+
Sbjct: 2081 SAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFV 2140
Query: 2522 DDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEV 2581
DD+NMP + YG Q PI LL+ ++ GY +D+ K+ I D+ + AMG GGGRN++
Sbjct: 2141 DDLNMPAKEVYGAQPPIELLRQWIDHGYWFDK-KDTTRLDIVDMLLVTAMGPPGGGRNDI 2199
Query: 2582 DPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGK-LTFCTLALYKNIV 2640
RF ++ ++ ++ L I+SSI+ H + + GK L T +Y++ V
Sbjct: 2200 TGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMFLRYGKMLVQATKTIYRDAV 2259
Query: 2641 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 2700
++ PTPSK HY+FNLRD SRV G++L Q V + +R+W +E RVF+DRLI +
Sbjct: 2260 ENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKE 2319
Query: 2701 DKQLVQQHIGSLVVEHFKDDVEVVMRD-------------PILFGDFQMALHEGEPRIYE 2747
D+Q+ + FK +E V+ + FGD+ E + +IY+
Sbjct: 2320 DRQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKP--ESDQKIYD 2377
Query: 2748 DIQDYEAAKALFQEILEEYNE-SNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGG 2806
+I D + + + LEE+N S M+LV+F A+EH++R+ R+++ D+GH LLVG+GG
Sbjct: 2378 EITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGG 2437
Query: 2807 SGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVA 2866
SG+QS ++L+ F + E+++I +++ Y+ N +REDLK + L++G+ K+ +FLF D +
Sbjct: 2438 SGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIK 2497
Query: 2867 EEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQG--MGPAKESVWQYFVNKSA 2924
+E F+E IN +L +G VP +F +EK I+ ++ A QG + S++ +F+ +
Sbjct: 2498 DESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVI 2557
Query: 2925 NNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAE 2984
N + L MSP+GD R R FP ++N IDWF WP AL VA FL +
Sbjct: 2558 NKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNI 2617
Query: 2985 NIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQC 3044
+E VV +SV S + KLRR NYVTP +YL+ I T+ LL+ K Q
Sbjct: 2618 RVE-VVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMR 2676
Query: 3045 KRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
R GL KL A Q+ + ++L + L S ++ +I T A+ KK L +
Sbjct: 2677 NRYLTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQ 2736
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
E + K E E LAE MP LEAA L L+ +D++ ++S PP V+
Sbjct: 2737 ADEKEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVK 2796
Query: 3165 TVCECILIMKGYK--------------ELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQV 3210
V E I IMKG K E W +K ++ D FL SL D D+I +
Sbjct: 2797 LVMESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTM 2856
Query: 3211 KNIK-GLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFY 3269
K I+ + ++ VS A G+ K+V A+ Y V + + PKRE++ E
Sbjct: 2857 KRIRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLA 2916
Query: 3270 LTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGS 3329
++L + + EL + L+ L +E +K+ L+E EI ++L+ A+KLISGLG
Sbjct: 2917 AQMQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGG 2976
Query: 3330 ENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPL 3389
E RW +L R L GD LL + ++Y GAFT ++R + N+ W + ++ IP
Sbjct: 2977 EKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ-WLAECKDKVIPG 3035
Query: 3390 SQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRK 3449
F L L D ++I W GLP D S+ NGI+ + + R+ L IDP QA WIK
Sbjct: 3036 FSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNM 3095
Query: 3450 EEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFI 3509
E+ N L V F+D ++++ LE +++ GTP L ++ E +D I+ +L K QG +++
Sbjct: 3096 EKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYM 3155
Query: 3510 ILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERR 3569
LG+ ++Y +F+LY+ T+L NP Y P V K ++N+ +T GL+DQLL ++ A E+
Sbjct: 3156 RLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKP 3215
Query: 3570 ELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSE 3629
ELEE++ LI E+++NK LK++ED +L L+ S GN+L++ + L +K + E+SE
Sbjct: 3216 ELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISE 3275
Query: 3630 KLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKK 3689
K K+A T ID R GY+P A A +FF +S++A + MYQYSL F+ ++ SL
Sbjct: 3276 KQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTH 3335
Query: 3690 SLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDF 3749
S L R++ I+D T SIYN+ C LFE+ KLLFS +TI I + + + +E F
Sbjct: 3336 STKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYF 3395
Query: 3750 FLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYD-- 3807
L G I+L+ WLS++ W +I+ S + L + +E N W+ YD
Sbjct: 3396 LLTGGIALDNPYPNPAPQWLSEKAWAEIVRASAL--PKLHGLMEHLEQNLGEWKLIYDSA 3453
Query: 3808 LDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEA 3867
EQ P + + +K++ILRC R D++ AV +++ MG+ Y++ P +
Sbjct: 3454 WPHEEQLPGSWKFSQGL---EKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQG 3510
Query: 3868 IFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAV 3927
+ S+ +P++F+LSP +DP L+K A+ G GG R + +++GQGQ +A +++ A+
Sbjct: 3511 SYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAI 3570
Query: 3928 ARGQWLMLQNCHLLVKWLKDLEKSLERITKP---HPDFRLWLTTDPTKGFPIGILQKSLK 3984
G W++LQNCHL W+ LEK E + P + FRLWLT+ P++ FP+ ILQ +K
Sbjct: 3571 KDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIK 3630
Query: 3985 VVTEPPNGLKLNMRATYFK--ISHEMLDQCPHPA--FKPLVYVLAFFHAVVQERRKFGKI 4040
+ EPP GL+ N+ +Y IS + Q A ++ +++ L FFHAVVQERR FG +
Sbjct: 3631 MTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNFGPL 3690
Query: 4041 GWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRR 4100
GWN+ Y+FNESD ++ M + +L +P+ +L YL GE YGGR D DRR
Sbjct: 3691 GWNIPYEFNESDLRISMWQIQMFLNDY-----KEVPFDALTYLTGECNYGGRVTDDKDRR 3745
Query: 4101 ILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL 4160
+L L F + ++ Y IP + +++ + LP+ PEVFGL
Sbjct: 3746 LLL----SLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGL 3801
Query: 4161 HPNAEIGYYTQAARDMW-AHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQ 4219
H NA+I Q ++ LL L Q+G SG S + + ++A++I +K+P+ FDL++
Sbjct: 3802 HENADITKDNQETNQLFEGVLLTLPRQSG--GSGKSPQEVVEELAQDILSKLPRDFDLEE 3859
Query: 4220 VRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLF 4278
V K + + VL QEL RFN+L + +SL L RA+ G+V MS+EL++V S+
Sbjct: 3860 VMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSML 3919
Query: 4279 IGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTAL 4338
+G +P +W + +LK LG ++ L R + + W+ + P V W+SG + +S+LT +
Sbjct: 3920 VGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGV 3979
Query: 4339 VQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKS 4398
Q RK P+D +VT + E N G ++ GL+LEGA WD + + +S
Sbjct: 3980 SQNYARKYTIPIDHIGFEFEVTPQETVMENNPE--DGAYIKGLFLEGARWDRKTMQIGES 4037
Query: 4399 KPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTT 4453
PK+L LPI+ + P E+ Q+ + PVY TS RR + V +L T
Sbjct: 4038 LPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTD 4097
Query: 4454 RHISHWVLQGV 4464
HW+ +GV
Sbjct: 4098 MPQKHWINRGV 4108
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1450 bits (3753), Expect = 0.0
Identities = 1104/4136 (26%), Positives = 1980/4136 (47%), Gaps = 406/4136 (9%)
Query: 566 PPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRGQEVK-QKYLEVGRT--MKEYEDRK 622
PPV+G+I W + + ++ + R V+++L V+ QK + G + MK
Sbjct: 642 PPVSGSIIWAKQIDRQLTAYMKR---VEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEI 698
Query: 623 YEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAV-----FAINFSPALREIINET 677
++ W +Q ++L I T E ST RG +NF P + + E
Sbjct: 699 FDDWARKVQQ-------RNLGVSGRIFTIE-STRVRGRTGNVLKLKVNFLPEIITLSKEV 750
Query: 678 KYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAE--SVLLKDHSQ 735
+ L+ LGF VP N A Q ++ + + + Y + + S+L+ +
Sbjct: 751 RNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKK 810
Query: 736 ELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINL 795
E+ + G L W S + Y+ + + F+ V DD+ L + E I+L
Sbjct: 811 EVQALIAEGIA-LVWESYKLDPYVQRLAETVFNFQEKV-------DDL---LIIEEKIDL 859
Query: 796 FKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGKAP 855
+ DH +L +V+ V N
Sbjct: 860 --------------------EVRSLETCMYDHKT-----FSEILNRVQKAVDDLNLHSYS 894
Query: 856 KLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVP-LFHTETILTAPEIILHPNTNEI 914
L + + +I +L + L+++ ++LG + AP++ P
Sbjct: 895 NLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPK 954
Query: 915 DKMCFHCVRNCVEITKHFVRWMNGSCIEC------------------PPQKGE------- 949
K H +R IT + ++N EC P + +
Sbjct: 955 IKNVVHELR----ITNQVI-YLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVH 1009
Query: 950 ----EEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKA 1005
EEE N + P +E++ V I+ + +Y++ W +Y+ LW +
Sbjct: 1010 YELTEEEKFYRNALTRMPDGPVALEESYSA---VMGIVSEVEQYVKVWLQYQCLWDMQAE 1066
Query: 1006 IVMEKFAAKKPPCVAYDEKLQFYSKIAYEVMRH-------PLIKDEHCIRLQLRHLANTV 1058
+ + E L + + ++ + K+ + + + + V
Sbjct: 1067 NIYNRLG----------EDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKV 1116
Query: 1059 QENAKSW----VISLGKLLNESAKE---ELYNLHEEMEHLAKNLRKIPNTLEDLKFVLAT 1111
SW + G++L + E ++ +E+E + + + + + +V +
Sbjct: 1117 NLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSL 1176
Query: 1112 IAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHA 1171
+I+ +EL YR+ Q FPP +D IE W A
Sbjct: 1177 KRKIKQFEKQVEL-YRNGQRLLEKQRFQ--FPPSWL--YIDNIEGEWG-----------A 1220
Query: 1172 LGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPGSVGD-----------DLDKGVELL 1220
DI R + ++ N +++I + + S + D ++ ++ L
Sbjct: 1221 FNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQAL 1280
Query: 1221 GVYERELARHEKSRQELANAEKLFDLPIT--MYPELLKVQKEMSGLRMIYELYEGLKVAK 1278
+YE + R + R++ A A++ +L T + +VQ + L+ + ++ L
Sbjct: 1281 TIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVW 1340
Query: 1279 EEWSQTL---WINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLL 1335
E+ Q W+++ + L++ ++ L L+ P +R + +++ +K + L+
Sbjct: 1341 EQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLV 1400
Query: 1336 LDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAI 1395
++LK+EAL+DRHWK+LM++ V + ++E TL ++ ++L K+ ++ +++ A E+A+
Sbjct: 1401 IELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVDLQKNEAIVKDVLLVAQGEMAL 1459
Query: 1396 EKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGP 1455
E+ +K+I + W + +V Y Q + ++ D++ + ++ ++ ++ S +
Sbjct: 1460 EEFLKQIREVWNTYELDLVNY----QNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKV 1515
Query: 1456 FLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEAKKFDNIDKVF 1514
F + WE L+ I + ++W+ VQR+W+YLE IF G DI+ LP E ++F +I F
Sbjct: 1516 FEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEF 1575
Query: 1515 KRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDD 1574
+M + K P++ L+ +++ L K QK+L +YL+ +R++FPRF+F+ D+
Sbjct: 1576 LALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDE 1635
Query: 1575 ELLSILGSSDPLC-VQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRK--IL 1631
+LL I+G+S + +Q+H KM+ ++S+ N+ +S +V + S EGE + F+ +
Sbjct: 1636 DLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS---VVLGISSREGEEVMFKTPVSI 1692
Query: 1632 RAEGRVEDWMTAVLNEMRRTNRLITKEAIFRY--------CEDRSRVDWMLLYQGMVVLA 1683
++ +W+T V EMR T + E++ + + + W+ YQ +V+
Sbjct: 1693 TEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVL 1752
Query: 1684 ASQVWWTWEVEDVFHKAQKGEKQA-MKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 1742
++Q+ W+ VE G A + + + ++ L + M R+K ++
Sbjct: 1753 SAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLI 1812
Query: 1743 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREP----DELNIRQCTGTFGYGYEY 1798
VH RD+ S I+ I A+ F+W SQ+RFY+D + +L+I+ F YG+EY
Sbjct: 1813 TELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEY 1872
Query: 1799 MGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNC 1858
+G+ +LV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC
Sbjct: 1873 LGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNC 1932
Query: 1859 GEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLT----- 1913
E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S Q+Q I+ AL
Sbjct: 1933 DETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDK 1992
Query: 1914 -----TFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEI 1968
T + +++ + M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++
Sbjct: 1993 TSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQV 2052
Query: 1969 MLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRG------ 2022
ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR
Sbjct: 2053 MLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIK 2112
Query: 2023 ---------------SSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPR 2067
+ +L E +L++++ + +PK V ED+PL L+SD+FPG+ R
Sbjct: 2113 REKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHR 2172
Query: 2068 VRYPDFNDAVEQVLEE------NGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSV 2121
+ +++V +E +G V + V+KV+Q+++ H M+VGP+ GKS+
Sbjct: 2173 GEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSM 2232
Query: 2122 VINTLCQAQTKL-GLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPT- 2179
L +A +L G+ +I++PKA+S LYG LDP TR+WTDG+ +++ R+I
Sbjct: 2233 AWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVR 2292
Query: 2180 -DKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYAS 2238
+ ++R++I+FDGDVD WVEN+NSV+DDN+LLTL NGER+ L + ++FEV DL+YA+
Sbjct: 2293 GELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYAT 2352
Query: 2239 PATVSRCGMVYVDPKNLKYRPYWKKWVNQI----------------------------PN 2270
ATVSRCGMV+ L + ++ ++ P
Sbjct: 2353 LATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPM 2412
Query: 2271 KVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEG 2330
Q + ++ + Y + + +V ++ A +L+ I+ T L + L ML
Sbjct: 2413 LQIQRDAATIMQPY--FTSNGLVTKALE--HAFQLEHIMDLTRLRCLGSLFSMLHQACRN 2468
Query: 2331 EIE----------DLDLLECYFLEALYCSLGASLLEDGRMKF----DEYIKRLASLSTVD 2376
+ ++ LE Y L ++ SL D R+K EYI+R+ ++
Sbjct: 2469 VAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPT 2528
Query: 2377 TEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEY-IHAPERKFINILVHTVDTT 2435
+ + D+ +W PW VP+ + + +++V T+DT
Sbjct: 2529 APNI------------PIIDYEVSIS-GEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTV 2575
Query: 2436 RTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQR 2495
R +L + +P++ G G+ KT T + L+ L + V+ +NFSS TT + +
Sbjct: 2576 RHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDME--VVGLNFSSATTPELLLK 2633
Query: 2496 NLEANVE-KRTKD--TYGP-PMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLY 2551
+ E +RT + P +GK L++F D++N+P +D+YGTQ+ I+ ++ ++E G Y
Sbjct: 2634 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2693
Query: 2552 DRGKELNCKSIRDLGFIAAMGK-AGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSIL 2610
R + + + F+ A GR + RF+ V V +P SL IY +
Sbjct: 2694 -RTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFN 2752
Query: 2611 KG------HTSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFN 2664
+ T+ E + A + F T++ + QD P HYI++ R+++R
Sbjct: 2753 RAMLRLIPSLRTYAEPLTAAM--VEFYTMS-QERFTQDTQP-----HYIYSPREMTRWVR 2804
Query: 2665 GLV-LTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVEHFKD-DVE 2722
G+ P V ++R+W +E LR+F DRL+ + +++ ++I ++ ++HF + D E
Sbjct: 2805 GIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDRE 2864
Query: 2723 VVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDAL 2782
M PIL+ ++ + P E+++DY A+ L+ + E + LVLF++ L
Sbjct: 2865 KAMSRPILYSNWLSK--DYIPVDQEELRDYVKAR------LKVFYEEELDVPLVLFNEVL 2916
Query: 2783 EHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDL 2842
+H+ R+ RI R +GH LL+GV G+GK +LSR A+ V++I + R Y+ F EDL
Sbjct: 2917 DHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDL 2976
Query: 2843 KSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQE 2902
+++ + G +N+ + F+ +++V + GFLE +N +L +G VP LF +E ++++Q +
Sbjct: 2977 RTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEG 3036
Query: 2903 ALKQG-MGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMP 2961
A K+G M + E ++++F ++ NLH+V M+P + L+ P + N ++WF
Sbjct: 3037 AQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGD 3096
Query: 2962 WPPQALHAVAKSFLG-------------YNPMI------PAENIENVVKHVVLVHQSVDH 3002
W +AL+ V K F Y P++ P + E +V V VHQ++
Sbjct: 3097 WSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQ 3156
Query: 3003 YSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLD 3062
+ + ++ R+ +TP++YLDFIN Y+ L EK Q L+ GL K+KE Q++
Sbjct: 3157 ANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVE 3216
Query: 3063 ELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKA 3122
EL + L + L K+AA L+++ + AE+KK +++E ++ +Q +VIA ++
Sbjct: 3217 ELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQM 3276
Query: 3123 EAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWK 3182
+ L +V P + A+ ++ + K + E+RS A PP V+ E I ++ G +WK
Sbjct: 3277 SVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWK 3336
Query: 3183 TAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLG---MLK 3239
+ ++ NF+ +++ + I+ + + +K ++ + E V++A L M+K
Sbjct: 3337 QIRSIIMRENFIPTIVNFSAEEISDAIREKMKK--NYMSNPSYNYEIVNRASLACGPMVK 3394
Query: 3240 FVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAA 3299
+ A + Y D+ + ++P R ++ +LE + +++ ++ + ++ + +Y
Sbjct: 3395 WAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVL 3454
Query: 3300 ILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFL 3359
I E Q ++ + +E ++ + L+ L +E RW + ++ + GDCLL AAF+
Sbjct: 3455 ISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFI 3514
Query: 3360 SYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELS 3419
+Y G F + R + W + + + I L++ E RW + LP D+L
Sbjct: 3515 AYAGYFDQQMRQNLFTT-WSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLC 3573
Query: 3420 VQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPF 3479
+N I+ R +R+PL IDP QA +I + + + SF D F K LE ++++G P
Sbjct: 3574 TENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPL 3633
Query: 3480 LFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSV 3539
L +DV+ Y DPV++ VL + ++ + GR I LGD+++D +F ++L+T+ + P +
Sbjct: 3634 LVQDVESY-DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDL 3692
Query: 3540 FGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRE 3599
+ +N+TVT L+ Q L+ ++ ER +++E+R L++ E + L+ LE SLL+
Sbjct: 3693 CSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQA 3752
Query: 3600 LATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILF 3659
L G +LD+ ++ TLE K +A EV+ K++ + +++ + Y P + + ++
Sbjct: 3753 LNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIY 3812
Query: 3660 FVLSEMALVNSMYQYSLIAFLEVFRLSL-----KKSLPDSILMKRLRNIMDTLTFSIYNH 3714
F + + ++ +YQYSL FL+++ L K + D +RL I L +N
Sbjct: 3813 FTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDH--TQRLSIITKDLFQVAFNR 3870
Query: 3715 GCTGLFERHKLLFSFNMT-IKIEQAEGRVPQE-ELDFFLKGNISLEKSKRKKPCAWLSDQ 3772
G+ + + F+ + IK++ G + E FL+GN + + L+ +
Sbjct: 3871 VARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVE 3930
Query: 3773 GWEDIILLS--EMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQ-FPVPLGYDNNITP--- 3826
E ++ LS F D ++ D + + W D S EQ P + TP
Sbjct: 3931 QAEAVVRLSCLPAFKDLIAKVQADEQ-----FGIWLDSSSPEQTVPYLWSEETPATPIGQ 3985
Query: 3827 -FQKLLILRCFRVDRVYRAVTDYVTVTMGEKY---VQPPMISFEAIFEQSTPHSPIVFIL 3882
+LL+++ FR DR+ +V+ +GE + ++ P+ + + P++P++
Sbjct: 3986 AIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCS 4045
Query: 3883 SPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQE-KVALQLLETAVARGQWLMLQNCHLL 3941
PG D + + LA ++ +A+G + A + + TAV G+W+ML+N HL
Sbjct: 4046 VPGYDASGHVEDLAAEQ---NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLA 4102
Query: 3942 VKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATY 4001
WL LEK L + +PH FRL+LT + P+ +L+ V EPP G+K NM T+
Sbjct: 4103 PGWLMQLEKKLHSL-QPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTF 4161
Query: 4002 FKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILN 4061
I + + P+ + L ++LA+FHA++QER ++ +GW+ Y+F ESD + + ++
Sbjct: 4162 SSIPVSRICKSPNERAR-LYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVD 4220
Query: 4062 TYL---TKAFQQRDP-RIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDT 4117
T+L K Q P +IPW +LK L+ + +YGGR + FD+R+L +++ FD+
Sbjct: 4221 TWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDS 4280
Query: 4118 FQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMW 4177
+ D ++P G +E+FV+ +E LP TP GL NAE T DM
Sbjct: 4281 EFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMI 4340
Query: 4178 AHLLELQ--------------PQTGESSSGISRDDYIGQVAKEIENKMPKV-FDLDQVRK 4222
+ +L++Q +T S+ R ++ + N + + L +++
Sbjct: 4341 SKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKR 4400
Query: 4223 RLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHI 4282
+ P +E++ KL+ + + LA++ + G+ +N L + L G +
Sbjct: 4401 TVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGIL 4460
Query: 4283 PNIWRRLAPDTLKSLGNWMVYFLRRFSQYML--------WVTESEPSVMWLSGLHIPESY 4334
P W ++ W+ F R Q E + + L GL +PE+Y
Sbjct: 4461 PRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAY 4520
Query: 4335 LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGC 4394
+TA Q + N W L+ L VT Q A G V+GL L+GA + K
Sbjct: 4521 ITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFG----VTGLKLQGATCNNNK-- 4574
Query: 4395 LIKSKPKVLVVDLPILKIIPI-EAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEAD 4449
S + LP+ ++ + + + K + PVY R + L+F D
Sbjct: 4575 --LSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRAD-----LIFTVD 4623
Score = 36.6 bits (83), Expect = 0.58
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 234 EVSDLAADPETVDILEQCVINWLNQISTAVEAQLKKTPQGKGPLAEIEFWRERNATLSAL 293
+ D DP ++ L+ V W+ +I + L + P L EI FW L +
Sbjct: 231 DFGDKVEDPTFLNQLQSGVNRWIREIQKVTK--LDRDPASGTALQEISFWLNLERALYRI 288
Query: 294 HEQTKLPIVRKVLDVIK 310
E+ + P V LD++K
Sbjct: 289 QEKRESPEVLLTLDILK 305
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1344 bits (3478), Expect = 0.0
Identities = 1073/3959 (27%), Positives = 1853/3959 (46%), Gaps = 332/3959 (8%)
Query: 563 KNHPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRG--QEVKQKYLEVGRTMKEYED 620
KN V +I W R L ++ TI ++ E L SD + Q ++ +K YE
Sbjct: 477 KNLSEVVNSIVWVRQLELKVDDTI----KIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQ 532
Query: 621 RKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYL 680
+++ W + L + SS E S + +++S L ++ E + L
Sbjct: 533 EQFDDWSRDIQSGLSDSRSGLCIEASSRIMELDSN---DGLLKVHYSDRLVILLREVRQL 589
Query: 681 EQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRV 740
LGF +P + VA KF + ++++ Y+ + + ++ ++ + ++
Sbjct: 590 SALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQI 649
Query: 741 FRS------GYKRLNW-NSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAI 793
++ G ++ W N + YI + A + + ++ K ++ ++ I
Sbjct: 650 IKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNI 709
Query: 794 NLFKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGK 853
+L + +++R D +R LA V +
Sbjct: 710 DLLR--------------------QQQRWKDGLQELRTGLA-----------TVEAQGFQ 738
Query: 854 APKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNE 913
A + ++ ++W ++Y+ L L++ N N+P + + + P E
Sbjct: 739 ASDMHAWKQHWNHQLYKALEHQYQMGLEALNE----NLPEINIDLTYKQGRLQFRPPFEE 794
Query: 914 IDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAV 973
I + ++ + I F GE + I + D + + +
Sbjct: 795 IRAKYYREMKRFIGIPNQF------------KGVGEAGDESIFSIMIDRNASGFLT---- 838
Query: 974 MIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFYSKIAY 1033
I + L L + K + + ++D ++EK + L+ K
Sbjct: 839 -IFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGK--- 894
Query: 1034 EVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAK 1093
EV R P C+ + + + + + L L +S + L+ + + +
Sbjct: 895 EVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAME 954
Query: 1094 NLRKIPNTLE---DLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPDAEKEL 1150
L +P ++E D + + E + + L + D RT+A L K
Sbjct: 955 VLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAK 1014
Query: 1151 VDKIESIWSN---LFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEGPG 1207
DK E + + + D + V G++K + Y ++E+F R+ PG
Sbjct: 1015 WDKFELMMESHQLMIKDQIEVMK--GNVK--------SRLQIYYQELEKFKARWDQLKPG 1064
Query: 1208 S------VGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEM 1261
+ LDK +L+ + E E +R++L + F L + + K++
Sbjct: 1065 DDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDI 1124
Query: 1262 SGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSV-TYY 1320
I+ YE + +E + WI + E FL R V SV T
Sbjct: 1125 ESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYL--FEEFLMNWHDRLRKVEEHSVMTVK 1182
Query: 1321 LEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTD 1380
L++++ +K IP+L ++ E L HW +L + +LE + +L + D
Sbjct: 1183 LQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFR----LLGLPRGTSLEKLLFGDLLRVAD 1238
Query: 1381 V-------LNEIVTAAIKEVAIEKAVKEILDTWE-NMKFTVVKYCKGTQERGYILGSVDE 1432
L ++ + A EV I +A++E LD W FT++ Y ++ +
Sbjct: 1239 TIVAKAADLKDLNSRAQGEVTIREALRE-LDLWGVGAVFTLIDYEDSQSRTMKLIKDWKD 1297
Query: 1433 IIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFI 1492
I+ + DN LQS+ S + F V WE+ L+ + E ++ +QRKW+YLE IF
Sbjct: 1298 IVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG 1357
Query: 1493 GGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQK 1552
R LP+E +F+ +D+ F+ IM + KD + + L + + L++CQK
Sbjct: 1358 ----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQK 1413
Query: 1553 SLNDYLDSKRNAFPRFFFISDDELLSILG-SSDPLCVQEHMIKMYDNIASLRFNDGDSGE 1611
SLN++L+ KR+AFPRF+FI DD+LL ILG S++P +Q H+ K++ I S+ F D
Sbjct: 1414 SLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCF---DEKS 1470
Query: 1612 KLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVD 1671
K ++AM S EGEV+ F+ + VE W+ + EM++T + KE + + VD
Sbjct: 1471 KHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVD 1530
Query: 1672 WMLLYQGMVVLAASQVWWTWEVEDVF--HKAQKGEKQAMKNYGRKMHRQIDELVTRITMP 1729
L+ ++ A Q+ +T +VE+ H + E Q + + + ID
Sbjct: 1531 -PSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKL--EQYTNIDTSSEDPGNT 1587
Query: 1730 LSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCT 1789
S K +++ +H D+V + + ++ W+ QLRFY + ++
Sbjct: 1588 ESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYM-KSDHTCCVQMVD 1646
Query: 1790 GTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKAL 1849
F Y YEY G +LV TPLTD+ YLTLTQA+ M LGG P GPAGTGKTE+ K L L
Sbjct: 1647 SEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLL 1706
Query: 1850 GLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALI 1909
G +V NC EG+D +++G+IF GL +CGAWGCFDEFNR++ SVLS +S QIQTI++AL
Sbjct: 1707 GRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALK 1766
Query: 1910 HQLTTFQFEGQEISLDSRMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQIC 1966
+ T + G+E+ ++S GIFITMNP GY GR +LP+++K LFRPV + PD + I
Sbjct: 1767 NHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIA 1826
Query: 1967 EIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRG---- 2022
E++L+SEGF +AK L++K+ ++ L+RE L+ Q HYD+GLRALK+VL +G L R
Sbjct: 1827 EVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKS 1886
Query: 2023 --SSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQV 2080
+ + E ++++ALR + KF F D F LI D+FPG++ V Y + + A++QV
Sbjct: 1887 GTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQV 1946
Query: 2081 LEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLY 2140
EE Y ++P Q+ K ++++E + R ++VGP+ GKS + L A K G K Y
Sbjct: 1947 FEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQY 2006
Query: 2141 ILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREI-NKPTDKKERKYILFDGDVDALWVE 2199
+NPKA+ +L G +D TR+W+DGVL+N R++ +P D +I+ DGD+D W+E
Sbjct: 2007 TMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSS--WIICDGDIDPEWIE 2064
Query: 2200 NMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRP 2259
++NSV+DDNRLLT+ +GERI+ + +FE DL ASPAT+SR GM+++ +
Sbjct: 2065 SLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNS 2124
Query: 2260 YWKKWVNQIP----NKVEQYNLNSLFEKYVPYLM---DVIVEGIVDGRQAEKLKTIVPQT 2312
K W+ P N +E + + FEK + +++ D +VE + G T
Sbjct: 2125 LIKSWLRNQPAEYRNNLENW-IGDYFEKALQWVLKQNDYVVETSLVG------------T 2171
Query: 2313 DLNMVTQLAKMLDALLEGEIEDLDLLECYFLEALYCSLGASLLEDGRMKFDEYIKRLASL 2372
+N ++ L D F+ L LG +L R++F + +
Sbjct: 2172 VMNGLSHLHGCRD-------------HDEFIINLIRGLGGNLNMKSRLEFTKEVFH---- 2214
Query: 2373 STVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINIL---- 2428
WA E P D ++D+ R + + PE + A + F N L
Sbjct: 2215 --------WAR--ESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADD--FSNGLTLPV 2262
Query: 2429 VHTVDTTRTTWILEQMVK--IKQPVIFVGESGTSKTATTQNFLKNLSEETNIVLMVNFSS 2486
+ T D R + + KQP I VG G K + L + + V+ S+
Sbjct: 2263 IQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCSA 2320
Query: 2487 RTTSMDIQRNLEAN---VEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKL 2543
+TTS + + L + T Y P +RL++++ D+N+P++D++GT +A L+
Sbjct: 2321 QTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQ 2380
Query: 2544 LLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG--GRNEVDPRFISLFSVFNVPFPSEES 2601
+L YD + L + ++ +A+M AGG GR+++ RF S+ + ++ +P E
Sbjct: 2381 VLTYQGFYD--ENLEWVGLENIQIVASM-SAGGRLGRHKLTTRFTSIVRLCSIDYPEREQ 2437
Query: 2602 LHLIYSSILKG--HTSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKF------HYI 2653
L IY + L+ H + + SI S K+ L ++VQ +KF HY
Sbjct: 2438 LQTIYGAYLEPVLHKNLKNHSIWGSSSKI----YLLAGSMVQVYEQVRAKFTVDDYSHYF 2493
Query: 2654 FNLRDLSRVFNGLV---LTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQL------ 2704
F L++ GL L + ++ + E R+F D+++ + L
Sbjct: 2494 FTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILT 2553
Query: 2705 --VQQHIGSLVVEHFKDDVEVVM----RDPILFGDFQMALHEGEPRIYEDIQDYEAAKAL 2758
Q GS ++++ D V Q G+P + D K +
Sbjct: 2554 SVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTD---LKDV 2610
Query: 2759 FQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAF 2818
++ L Y N ++++LF + LE+++R+ R++ G LL G G G+++++ L +
Sbjct: 2611 IKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSH 2670
Query: 2819 TASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNML 2878
+F +SRGY F+ DLK + GIE + ++ L D FLE+IN++L
Sbjct: 2671 MHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLL 2730
Query: 2879 TSGIVPALFSEEEKESILSQIGQEALKQG-MGPAKESVWQYFVNKSANNLHIVLGMSPVG 2937
+SG VP L++ EE E +L + +A + G GP V+ YF + NLHIVL M
Sbjct: 2731 SSGEVPGLYTLEELEPLLLPLKDQASQDGFFGP----VFNYFTYRIQQNLHIVLIMDSAN 2786
Query: 2938 DTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLG-------YNPMIPAENIE--- 2987
C + P + + W W ++ + + YN E +
Sbjct: 2787 SNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNS 2846
Query: 2988 ---NVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQC 3044
+ +K +L+H+S Y TP Y+ F++ YS + K + + +
Sbjct: 2847 VDPDFLKSFLLIHESCKAYG------------ATPSRYMTFLHVYSAISSSKKKELLKRQ 2894
Query: 3045 KRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
L G+ KL EA +DELN+K EQ ++L K +A L+ I V+ A E+K E
Sbjct: 2895 SHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELE 2954
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
I E+ I K + + L EV P++ AKL + + ++EIRS PP ++
Sbjct: 2955 RLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIR 3014
Query: 3165 TVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTT 3224
+ E +L + G + +W + K ++ + D +I++ ++++ LL +
Sbjct: 3015 DILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSF 3074
Query: 3225 EEMEA--VSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNEL 3282
+ A S A + +V+A + Y V I P + A LE N T+ +++ L
Sbjct: 3075 DPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELL 3134
Query: 3283 AAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELM 3342
++ +++ L K+++ E KL+ E + + AA+ LI+ L E+ RW + E+
Sbjct: 3135 NSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEIT 3194
Query: 3343 HRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDD 3402
L L AAF++Y A R + ++ LE+ F L L +
Sbjct: 3195 EELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEK-------FDLRRFLCTE 3247
Query: 3403 VEISRWGSQGLPPDELSVQNGI-------LTTRASRFPLCIDPQQQALNWIKRKEEKNNL 3455
E W S+GLP D+LS++N + L + + P IDP QA W+K + + L
Sbjct: 3248 SEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRL 3307
Query: 3456 RVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFII-LGDK 3514
V + D +F+ LE+++++G + +++D ++PV+ +L +++ V+QG ++++ +GDK
Sbjct: 3308 EVINQQDSNFITALELAVRFGKTLIIQEMDG-VEPVLYPLLRRDL-VAQGPRYVVQIGDK 3365
Query: 3515 EVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQ 3574
+DY+ FRL+L+T+ NP P +N+T T GL QLL++ + +E+ +LEEQ
Sbjct: 3366 IIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQ 3425
Query: 3575 REHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLA 3634
+ L+Q+ + K L LE+SLL LATS GN+L+N DL+ +L +TK+ + + E LK +
Sbjct: 3426 KTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKES 3485
Query: 3635 EKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDS 3694
K + +D+ RD Y P A + ++F++S+++ +N+MY++SL AFL +F+ +L+
Sbjct: 3486 YKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSE 3545
Query: 3695 ILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFF---- 3750
+R+++++ +L +Y + C LF+ +L+F+ + + + E D F
Sbjct: 3546 NTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPE--LFQENEWDTFTGVV 3603
Query: 3751 ----LKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWY 3806
L+ S +K + + P +W+ + + L + L + +W+ +Y
Sbjct: 3604 VGDMLRKADSQQKIRDQLP-SWIDQERSWAVATLKIALPSLYQTL---CFEDAALWRTYY 3659
Query: 3807 DLDSLEQ-FPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISF 3865
+ EQ FP L ++ FQ++L+++ R DR+ A+ + T+G K V P ++
Sbjct: 3660 NNSMCEQEFPSILA--KKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNL 3717
Query: 3866 EAIFEQSTPHSPIVFILSPGSDPATDLMKL--AERSGFGGNRLKFLAMGQGQEKVALQLL 3923
+ +++++ PI+ I+SPG+DP+ +L +L AERSG ++ +AMGQGQ +A+Q+L
Sbjct: 3718 KRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQ---VAMGQGQADLAIQML 3774
Query: 3924 ETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSL 3983
+ G WL L+N HL+V WL LEK L + +P FRLWLT + F +LQ SL
Sbjct: 3775 KECARNGDWLCLKNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEVHPNFTPILLQSSL 3833
Query: 3984 KVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWN 4043
K+ E P GLK N+ TY + E + + + ++ LA+FHA QERR + GW
Sbjct: 3834 KITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWT 3893
Query: 4044 VYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILT 4103
+Y+F+ SD + I++ A + W + L+ +YGGR + FD R+L
Sbjct: 3894 KFYEFSLSDLRAGYNIIDRLFDGA-----KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQ 3948
Query: 4104 IYMDEYLGDFIFDTFQPFHFFRNKE----VDYKIPVGDEKEKFVEAIEALPLANTPEVFG 4159
Y+ ++ + D F RNK+ +P + IE +P + P FG
Sbjct: 3949 SYLKQFFNSSVIDVFNQ----RNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFG 4004
Query: 4160 LHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIE--NKMPKVFDL 4217
L N + + + L + ++ + S R+ + +++ + K+ + +L
Sbjct: 4005 LPANIARSSQRMISSQVISQ-LRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNL 4063
Query: 4218 DQVRKRLGTGLSPTSVVLLQELERFN--KLVVRMTKSLAELQRALAGEVGMSNELDDVAR 4275
+ + ++ LE+FN +LV + +SLA L + + G +S+E+ +A
Sbjct: 4064 IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLAS 4123
Query: 4276 SLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMW-----LSGLHI 4330
+L P W+ L ++ + R WV ++E + LS L
Sbjct: 4124 ALLNQKCPLAWQSKWEGPEDPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFH 4182
Query: 4331 PESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWD 4389
P+++L AL Q T R G +D S F K + + A +SGL LEG +D
Sbjct: 4183 PDTFLNALRQETARAVGRSVD-SLKFVASWKGR-----LQEAKLQIKISGLLLEGCSFD 4235
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 1093 bits (2828), Expect = 0.0
Identities = 694/2095 (33%), Positives = 1125/2095 (53%), Gaps = 115/2095 (5%)
Query: 828 MVRWYLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLI 887
M WY + L TK E L K KL ++Y + L L+ + ++ F L
Sbjct: 260 MNTWYPKVINLFTKKEAL----EGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLF 315
Query: 888 ----LGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKH---FVRWMNGSC 940
+P+F E ++ +P +++ V E ++ W++G+
Sbjct: 316 DPKDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTS 375
Query: 941 IECPPQKGEEEEVVIINFYNDISLNPQIIEQAV-MIPQNVHRILINLMKYLQKW-KRYRP 998
+N D L ++ AV + VHR L K+ + + ++Y
Sbjct: 376 TP-------------VNL--DTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYN- 419
Query: 999 LWKLDKAIV--MEKFAAKKPPCVAYDEKLQFYSKIAYEVMRHPLIKDEHCIRLQLRHLAN 1056
W LD V +E F + Y E ++ + +A E+M P +RL L
Sbjct: 420 -WLLDGTAVENIETFQTEDHTFDEYTEFIEKFLSLASEIMLLPQWIHYTMVRLDCEDLKT 478
Query: 1057 TVQENAKSWVISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNTLEDLKFVLATIAEIR 1116
+ AK++ L + ++E + E E + ++ K+P T E++ +++ + + R
Sbjct: 479 GLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKAR 538
Query: 1117 SKSLVMELRYRDVQERYRTMAMY-NLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDI 1175
+ + EL R +QE R M+ + ++F E ++ +W N + L +
Sbjct: 539 TVG-IEELILR-IQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKINPIFDENDELIEN 596
Query: 1176 KRTFTELTRGEIMNYR----VQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHE 1231
+ E E+M R ++IE+ ++R + + + + V + ++ + E
Sbjct: 597 AKHKKE---NELMAKREKLILEIEKESRRMEEFTEFAELERMQQYVTDVRQLQKRIQESE 653
Query: 1232 KSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNV 1291
++ Q + E+LF +T YPEL K++ + + + + +++ W +++LN
Sbjct: 654 EAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNG 713
Query: 1292 QILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIP---LLLDLKNEA------ 1342
+ ++ +E F R + K + + E + A K S+ + + K+ A
Sbjct: 714 ESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCR 773
Query: 1343 LRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEI 1402
+R RHWK++ E TL + + L + + I A KE ++EKA+ +
Sbjct: 774 MRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTM 833
Query: 1403 LDTWENMKFTVVKYCKGTQERGY-ILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVH 1461
+ TWE++ F + Y ++ G IL SVDEI LDD Q++ GS F+ PF +
Sbjct: 834 IGTWEDIAFHISLY----RDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIK 889
Query: 1462 KWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGET 1521
WE L I E I+ W+ VQ +W+YLE IF DI Q+PEE ++F +D+ ++ IM
Sbjct: 890 AWEDRLIRIQETIDEWLKVQAQWLYLEPIFCSEDIMQQMPEEGRQFQTVDRHWRDIMKFC 949
Query: 1522 LKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG 1581
KDP + L LQN +E LEK K LN YL+ KR FPRFFF+S+DE+L IL
Sbjct: 950 AKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILS 1009
Query: 1582 SS-DPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILR---AEGRV 1637
+ DPL VQ H+ K ++ IA L F + AM S+EGE +E ++ A G V
Sbjct: 1010 ETKDPLRVQPHLKKCFEGIAKLEFLPNLD----IKAMYSSEGERVELIALISTSAARGAV 1065
Query: 1638 EDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVF 1697
E W+ V + M R+ + A Y E R DW+ + G VVL SQ++WT E ++V
Sbjct: 1066 EKWLIQVEDLMLRSVHDVIAAARLAYPESARR-DWVREWPGQVVLCISQMFWTSETQEVI 1124
Query: 1698 HKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIR 1757
G + +K Y +++ Q++E+V + LSK R ++ IDVHARD+V I+
Sbjct: 1125 ----SGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMIK 1180
Query: 1758 GSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLT 1817
+ +F W +QLR+YW+ E + I C Y YEY+G + RLVITPLTDR Y T
Sbjct: 1181 MGVSHDTDFLWLAQLRYYWENENARVRIINCN--VKYAYEYLGNSPRLVITPLTDRCYRT 1238
Query: 1818 LTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQC 1877
L A + LGGAP GPAGTGKTETTKDLAKAL + CVV NC +G+DY A+GK F GLA
Sbjct: 1239 LIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASS 1298
Query: 1878 GAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPG 1937
GAW CFDEFNRI+ VLSV++ QI I+ A+ +L F FEG E+ L+ + ITMNPG
Sbjct: 1299 GAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPG 1358
Query: 1938 YAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLS 1997
YAGR+ELP+++K LFR V ++VP+ I EI L+S GFL A+ L+ K+ + Y+L EQLS
Sbjct: 1359 YAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLS 1418
Query: 1998 KQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLIS 2057
Q+HYD+G+RA+K+VLV AG LK + ED++L+R+++D+N PKF+ D+PLF G+ S
Sbjct: 1419 SQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITS 1478
Query: 2058 DLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRG 2117
DLFPG+ P Y +F + + + + ++K++Q +E M+ RH M+VG
Sbjct: 1479 DLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFA 1538
Query: 2118 GKSVVINTLCQAQTKL-----GLTTKLY--ILNPKAVSVIELYGILDPTTRDWTDGVLSN 2170
K+ V++ L T + G K+ +NPK++++ +L+G DP + +WTDG+++N
Sbjct: 1539 AKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTDGIVAN 1598
Query: 2171 IFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFE 2230
FRE ++ +RK+++FDG +D LW+E+MN+V+DDN+ L L +GE I++ +L+FE
Sbjct: 1599 TFREF-ALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQMSLIFE 1657
Query: 2231 VGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMD 2290
DL ASPATVSRCGM+Y++P L + P W+N + + + +L +L+
Sbjct: 1658 TMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGLFAWLIP 1717
Query: 2291 VIVEGIVDGRQAEKLKTIVPQTDLNM-----VTQLAKMLDALLEGEIEDLDL-LECYFLE 2344
+ V+ Q L T + L + ++ K + + L + F+
Sbjct: 1718 PSLNQRVELFQLNYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLHQQACFIF 1777
Query: 2345 ALYCSLGASLLEDGRMKFDEYIKRLA-----SLSTVDTEGVWANPGELPGQLPTLYDFHF 2399
+L S+G S DGR FD +I+ + D+ G W P + G +YD+ +
Sbjct: 1778 SLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKWECPFDEKG---LVYDYMY 1834
Query: 2400 DNK-RNQWVPWSKLVPE-YIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGES 2457
+ K + +WV W++L+ + + K +I+V T+DT R T++++ + +P++FVG +
Sbjct: 1835 ELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITYAKPLLFVGPT 1894
Query: 2458 GTSKTATTQNFLKN-LSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKR 2516
GT K+ ++ L N L ++ +N S+RT++ +Q + A ++KR K +GPPMGK+
Sbjct: 1895 GTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRKGVFGPPMGKK 1954
Query: 2517 LLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGG 2576
++F+DDMNMP +++YG Q PI LL+ + G+ YD K+ + ++ D+ IAAMG GG
Sbjct: 1955 CIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDL-KDTSKITLVDIELIAAMGPPGG 2013
Query: 2577 GRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTLA 2634
GRN V PR I F++ ++ S+E++ I+SSI+ + T F + ++ T+
Sbjct: 2014 GRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIGNQIVNGTME 2073
Query: 2635 LYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHD 2694
+YK V++L PTP+K HY FNLRD SRV G +L + M+R++ +E LRVF+D
Sbjct: 2074 IYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFVHEVLRVFYD 2133
Query: 2695 RLISETDKQLVQQHIGSLVVEHFKDDVEVVMRD--------------PILFGDFQMALHE 2740
RLI++ D++ + Q +++ +HFK+ + ++FGD+ E
Sbjct: 2134 RLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMFGDYMNPDLE 2193
Query: 2741 GEPRIYEDIQDYEAAKALFQEILEEYNESN-TKMNLVLFDDALEHLTRVHRIIRMDRGHA 2799
G+ R+Y +I + + + L+EYN+++ T+MNLV+F LEHL+R+ R+++ G+A
Sbjct: 2194 GDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICRVLKQSGGNA 2253
Query: 2800 LLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENK 2854
LLVG+GGSG+QSL+RLA A +F+ +S+ Y N +RED+KS ++ + + N+
Sbjct: 2254 LLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKS-FIAVPVTNR 2307
Score = 481 bits (1239), Expect = e-135
Identities = 268/790 (33%), Positives = 426/790 (53%), Gaps = 26/790 (3%)
Query: 3695 ILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGN 3754
IL KRLR + D T+++Y + C LFE+ KLLFSF + + A + +EL F L G
Sbjct: 2315 ILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGG 2374
Query: 3755 ISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQF 3814
+SL+ +++ WL D+ WE+I SE + F L + W+E YD
Sbjct: 2375 VSLKSAEKNPDPTWLQDKSWEEICRASEFPA--FRGLRQHFCEHIYEWREIYDSKEPHNA 2432
Query: 3815 PVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTP 3874
P D N+ QK++ILRC R D++ A+T+YVT +G+K+V+PP + S
Sbjct: 2433 KFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNC 2492
Query: 3875 HSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVARGQWLM 3934
P++F+LSPG+DP L+K A GN+ + +++GQGQ +A ++++ A+ G W+
Sbjct: 2493 TIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEGTWVC 2552
Query: 3935 LQNCHLLVKWLKDLEKSLERITKP--HPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNG 3992
LQNCHL V W+ LEK E T + FRLWLT+ P+ FP+ ILQ +K+ EPP G
Sbjct: 2553 LQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNEPPTG 2612
Query: 3993 LKLNMRATYFK---ISHEMLDQC--PHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYD 4047
L+LN+ +Y E C A++ L++ + FFHA+VQER+KFG +GWN+ Y
Sbjct: 2613 LRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYG 2672
Query: 4048 FNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMD 4107
FNESD ++ + L ++ + IP+ ++ YL GE YGGR D +DRR+L +
Sbjct: 2673 FNESDLRISIRQLQLFINEY-----DTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLA 2727
Query: 4108 EYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIG 4167
++ +I + H+ + +Y P E ++E I+ LP PE+FGLH N +I
Sbjct: 2728 DFYNLYIVEN---PHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDIS 2784
Query: 4168 YYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTG 4227
Q + ++ LL Q + ++ + S D + ++ K+I NK+P FD++ ++
Sbjct: 2785 KDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVR 2844
Query: 4228 LSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIW 4286
+ + VL+QE+ERFN L++ + +L +L++A+ G V M + L+ ++ SL +G +P IW
Sbjct: 2845 YEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIW 2904
Query: 4287 RRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESYLTALVQATCRKN 4346
+ + +LK LG+++ FL R + W +P V WLSG +++LT +Q RK
Sbjct: 2905 AKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKY 2964
Query: 4347 GWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVD 4406
P+D +V +D E G ++ GLYL+GA WD E G L + PK+L
Sbjct: 2965 TTPIDLLGYEFEVIPSDTSDTSPE---DGVYIHGLYLDGARWDRESGLLAEQYPKLLFDL 3021
Query: 4407 LPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAM-----GVGLVFEADLFTTRHISHWVL 4461
+PI+ I P + R+ + + P+Y TS R+ + V L T + HW+
Sbjct: 3022 MPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIK 3081
Query: 4462 QGVCLTLNSD 4471
+GV L D
Sbjct: 3082 RGVALLCQLD 3091
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 764 bits (1974), Expect = 0.0
Identities = 526/1885 (27%), Positives = 934/1885 (49%), Gaps = 235/1885 (12%)
Query: 2789 HRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLK 2848
+R++ + + +G+ G GK++ + LA + +++ + +S + F+E K +++
Sbjct: 2652 YRLLSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIH 2711
Query: 2849 LGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGM 2908
G++ K + + + ++ ++ FLE +N +++SG +P LF E +SI +I + G
Sbjct: 2712 AGLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGH 2771
Query: 2909 GPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALH 2968
++S+ +F + NLHI + MSP G + R CR +P M+++ IDW+ WP +AL
Sbjct: 2772 MDNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALL 2831
Query: 2969 AVAKSFLGYNPMIPAENIENVVKHV----VLVHQSVDHYSQQFLQKLRRSNYVTPKNYLD 3024
VA SFL + EN EN+ + + V +H+S+ ++++ ++ R Y TP +YL
Sbjct: 2832 IVANSFL--KEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQ 2889
Query: 3025 FINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEA 3084
F+ T++ +L + + + R GL + EAT + E+ ++L + +K+ E
Sbjct: 2890 FMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETET 2949
Query: 3085 LLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQK 3144
L+E++ ++ V E+ + L ++ + E+ +++ + L V+P + A + L
Sbjct: 2950 LMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNA 3009
Query: 3145 LDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDS 3204
LDK+DV E+R + +PP V TV + I+ K+ NW TAK ++S+ FL+ L+ +D DS
Sbjct: 3010 LDKADVAELRVYTRPPFLVLTVMNAVCILL-QKKPNWATAKLLLSETGFLKKLINLDKDS 3068
Query: 3205 ITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARL 3264
I +K ++ + ++ VS A + ++V A+ Y +V + + PK+ +VA
Sbjct: 3069 IPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQVAEA 3128
Query: 3265 ERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLI 3324
+ + ++ L Q L +++ L L A Y+ + EKQ L + RR A L+
Sbjct: 3129 QNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCASVLL 3188
Query: 3325 SGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILE 3384
+ L E RW ++++ ++ +LGD LL AA + Y G T EFR +VN+ W+ +E
Sbjct: 3189 TVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVNK-WETFCIE 3247
Query: 3385 REIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALN 3444
I LS F L ++ EISRW +QGLP + SV+N IL ++PL IDP +QA
Sbjct: 3248 NGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQAHK 3307
Query: 3445 WIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQ 3504
WI R+ E + L+ S D ++ K++E ++K G L +++ E + P + +L+K+I +
Sbjct: 3308 WI-RQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDIYQKK 3366
Query: 3505 GRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLV 3564
G FI +GD E +Y+SNFRLYL+T++ NP + PSV+ +IN+TVT +GL+DQLLS +V
Sbjct: 3367 GHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLLSTVV 3426
Query: 3565 AYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKA 3624
+E LE+QR L++ S + L++LE+ L L + G++LD+ +V TL ++K +
Sbjct: 3427 THEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKSKMTS 3486
Query: 3625 TEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFR 3684
E+S++++ +K +I +R Y P A RGA+L+F+++++ +N MYQ+SL F +VF
Sbjct: 3487 NEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFHQVFV 3546
Query: 3685 LSL-------------KKSLP------------------DSILMKRLRNIMDTLTFSIYN 3713
S+ +K P ++L K +++ +D LT SI+
Sbjct: 3547 SSVVSKSKEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTKSIFK 3606
Query: 3714 HGCTGLFERHKLLFSFNMTIKIEQAE----------GRVPQEELDFFLKGNI------SL 3757
+ LF KL FSF + I Q G +P+EE + FL I +L
Sbjct: 3607 VVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINIKSAL 3666
Query: 3758 EKSK--------RKKPCAWLSDQGW----------EDIILLSEMFSDNFGQLPDDVENNQ 3799
+S+ + WLSD W E LL + N Q D +N++
Sbjct: 3667 SQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQW-DTFKNSK 3725
Query: 3800 TVW---------------------QEWYDLDSLEQFPVPLGYD-NNITPFQKLLILRCFR 3837
V+ +E L+ ++ P+ + +T FQ+L++++ R
Sbjct: 3726 AVYSLISTPFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVKVLR 3785
Query: 3838 VDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAE 3897
+ + +V ++T MG KY+Q ++ + ++ S +P++ I + G D L++ A+
Sbjct: 3786 PESLNNSVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLRFAQ 3845
Query: 3898 RSGFGGNRLKFLAMGQGQEKVALQLLETAVAR-GQWLMLQNCHLLVKWLKDLEKSLERIT 3956
+ + +++G+ Q A L+ A+ + QW+ LQNCHL ++ L +E
Sbjct: 3846 ELKGTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMPRLCTIVESFN 3905
Query: 3957 KPH----PDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATY-----FKISHE 4007
P+ P+FRLWL++ FPI +L+K LK+ E P GLK N+ T+ +++ E
Sbjct: 3906 SPNVTIDPEFRLWLSSKSYSSFPIPVLKKGLKIAVESPQGLKSNLLQTFGCTGSGEVTEE 3965
Query: 4008 MLD--QCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLT 4065
+ + C +K L++ L FF+AV+ ER+ +G +GWN+ Y FN SD V +++L L
Sbjct: 3966 IFENPDCGQ-WWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVAIKVLENSL- 4023
Query: 4066 KAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFR 4125
+ P I W +L+YLIGEV+YGGR ID++D+R L + ++ + F F R
Sbjct: 4024 ----RGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLK--DDFSFSR 4077
Query: 4126 NKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQP 4185
+ + + ++ I++LP + PEV G+HP A + +L+ +QP
Sbjct: 4078 SASI----------KDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQP 4127
Query: 4186 QTGESSSGI----SRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVV------- 4234
+T ++ I S+D+ + ++ ++ ++P + +++ +GT + S++
Sbjct: 4128 KTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEI--AVGTPSTLKSMMSSSIWES 4185
Query: 4235 -------------------LLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVAR 4275
L QE++RF+KL+ + KSL +LQ A+ GE+ ++ EL+++
Sbjct: 4186 LSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFN 4245
Query: 4276 SLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFS---------------QYMLWVT---- 4316
S +P +W++ A + K L +W+ ++R + +YM +VT
Sbjct: 4246 SFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQ 4305
Query: 4317 --------------------ESEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLF 4356
E PS WL P+++L A++Q R G +D T F
Sbjct: 4306 SIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALT-F 4364
Query: 4357 TQ--VTKFQDADE-----------VNERAGQ-------GCFVSGLYLEGADWDIEKGCLI 4396
T ++ D DE + RA + G ++ GL++EGA W+ E+ L
Sbjct: 4365 THHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKILE 4424
Query: 4397 KSKPKVLVVDLPILKIIPIEAHRLKLQN----------TFRTPVYTTSMRRNAMG----- 4441
S P + D P + +P + K N F PVY T R +
Sbjct: 4425 DSLPLEMCCDFPDIYFLPTKI-STKTPNASNQTDSELYAFECPVYQTPERSRILATTGLP 4483
Query: 4442 VGLVFEADLFTTRHISHWVLQGVCL 4466
+ L T + SHW+ V L
Sbjct: 4484 TNFLTSVYLSTKKPPSHWITMRVAL 4508
Score = 681 bits (1757), Expect = 0.0
Identities = 454/1411 (32%), Positives = 703/1411 (49%), Gaps = 197/1411 (13%)
Query: 1232 KSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNV 1291
+S N E++ + ++ E+ ++ +++ + ++E E K A EW + +++V
Sbjct: 970 QSHMHSVNVEEITQIVLS---EISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDV 1026
Query: 1292 QILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKEL 1351
+ +Q + + + L + + + +L+ + FK +P+++ L N L+ RHW+ L
Sbjct: 1027 ESVQRNVSKLMHIISVLEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEAL 1086
Query: 1352 MEKTSVFFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKF 1411
E + + +EN+ A+++ ++ + +N++ T+A E A+EK + +I+D W
Sbjct: 1087 QEIIGKSVPLDKNCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPL 1146
Query: 1412 TVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIG 1471
++ + +I+ S+D+I L+++ L +I GS +GP V++W++ L+L
Sbjct: 1147 PLILHHTEIYSI-FIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFS 1205
Query: 1472 EVIEIWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCC 1531
+E WM QR W+YLE +F +IR QLP E + F + ++K+IM + +
Sbjct: 1206 YTLEEWMNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQNKQNALQIT 1265
Query: 1532 EAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQE 1590
+ L LQN + LE +KSL DYL+ KR FPRF+F+S+ ELL IL S +P VQ
Sbjct: 1266 TSAGVLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQP 1325
Query: 1591 HMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRR 1650
H++K ++NI L D G V +ISAEGE + K +R VE W+ V M
Sbjct: 1326 HLVKCFENIKQLLIWKQDIGPPAVKMLISAEGEGLVLPKKIRVRSAVEQWLVNVEKSMFD 1385
Query: 1651 TNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKN 1710
+ K+ + Y +++L SQ+ + + F + EK +
Sbjct: 1386 ----VLKKERYIY--------------NIILLFQSQIMFYNDCVKSFVSSYSREKLEKVH 1427
Query: 1711 YGRKMHRQIDELVTRITMPLSKNDRKKY-NTVLIIDVHARDIVDSFIRGSILEAREFDWE 1769
G H ++E+ + + S + K +LI+ VH RDIV + + +I A +F+W
Sbjct: 1428 AGLMCH--LEEVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWT 1485
Query: 1770 SQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGA 1829
L++ W+ + + Q +F YGYEY+G RLVITPLTDR +LTL +AL + LGG
Sbjct: 1486 RHLQYKWNEKQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGC 1545
Query: 1830 PAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRI 1889
PAGPAGTGKTET KDLAK+LG CVV NC E +DY+ V K F GL Q GAW CFDEFN I
Sbjct: 1546 PAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLI 1605
Query: 1890 DASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVK 1949
D VLSVI+SQI TI+ A + F EG+EI ++ +FITMNP Y G ELP+++K
Sbjct: 1606 DLEVLSVIASQILTIKAAKDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLK 1665
Query: 1950 ALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRAL 2009
+LFRPV ++VP Q I EI+LFS GF A +L+ K+T LY+LAR+QLS+Q HY+FGLR+L
Sbjct: 1666 SLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSL 1725
Query: 2010 KSVLVMAGELKRGS---SDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCP 2066
K VL+MAG KR S+ E ++++ A+R+ +LPK EDVPLF +I D+FP +
Sbjct: 1726 KIVLIMAGTKKREFKCLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVL 1785
Query: 2067 RVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTL 2126
+V + ++ G Q +K++Q + + M+VGPT GGK+ V L
Sbjct: 1786 KVNQLALEKVIYTATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRIL 1845
Query: 2127 CQAQTKLGLT--------------------TKLYILNPKAVSVIELYGILDPTTRDWTDG 2166
+A T L + + +LNPK V++ ELYG LDP T +WTDG
Sbjct: 1846 EKALTLLPIADFLSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDG 1905
Query: 2167 VLS----------------------------------------------NIFREINKPTD 2180
+LS NIF EI K
Sbjct: 1906 LLSATIRSYVYFNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVVK 1965
Query: 2181 KKER-----KYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQ 2235
E ++I+ DG VD WVEN+NSV+DD R L LAN ERI L ++FEV +L
Sbjct: 1966 IPENHNFDWQWIILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLS 2025
Query: 2236 YASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLF-------------- 2281
ASPATVSRC MVY+DP +L + PY K W+ + + Q ++ L
Sbjct: 2026 QASPATVSRCAMVYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFI 2085
Query: 2282 ---EKYVPYLMDVIVEGIVDGRQAEKLKTIVPQT-------DLNMVT--QLAKMLDALLE 2329
+K+ PY M+ I I R + + + DLN + + +++
Sbjct: 2086 RNRQKFQPYPMEDITVVITLCRILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVTF 2145
Query: 2330 GEIEDLD---------------LLECYFLEALYCSLGASLLEDGRMK------------- 2361
+IE D +++ F+ A + G +L + +
Sbjct: 2146 KDIEKRDENTWYPEKNPDKLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPSLEPDS 2205
Query: 2362 -------FDEYIKRLASLSTVDTEGVWANPGELPGQ--------LPT----LYDFHFDNK 2402
FD+ + L S+ + W + G+ G+ LPT ++ + D +
Sbjct: 2206 LAKVTYDFDKLVHELFGNSS---QVGWKHWGQSQGRRRKGNCINLPTGECSIFGYFVDIE 2262
Query: 2403 RNQWVPWSKLVPEYIHAPER-------------KFINIL--------VHTVDTTRTTWIL 2441
+ +++PWS LVP +R F+ I T DTT ++++
Sbjct: 2263 QCEFIPWSDLVPNDQTLIQRGTSLLTNLQRSGGNFLKITECGECINYTATRDTTCLSFLM 2322
Query: 2442 EQMVKIKQPVIFVGESGTSKTATTQNFLKNL 2472
++K PV+ GESG KTA L+ L
Sbjct: 2323 SLLLKNSCPVLLTGESGVGKTAAINQMLEKL 2353
Score = 153 bits (386), Expect = 4e-36
Identities = 93/273 (34%), Positives = 148/273 (54%), Gaps = 13/273 (4%)
Query: 2441 LEQMVKIKQPVIFVGESGTS-------KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDI 2493
L+Q + I P +G+S + T + LKN + +V +NFS+ T+
Sbjct: 2382 LKQNITILIPETHKTATGSSDNPTKKPEVRTNKKLLKNNDHKGVVVSTINFSTNVTAAKT 2441
Query: 2494 QRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDR 2553
+ + + +RTKDT G P R+L+F+DDMNMP D YG Q P+ L++ LL+ G +YD
Sbjct: 2442 KEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLELIRQLLDLGGVYDT 2501
Query: 2554 GKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGH 2613
K K+I+DL +AA N++ PR + FS+ +P PS++ L I+ + L +
Sbjct: 2502 EKN-TWKNIQDLSIVAACVPV---VNDISPRLLKHFSMLVLPHPSQDILCTIFQAHLGIY 2557
Query: 2614 TS--TFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNP 2671
S F + ++ C+LA+Y + Q++ PTP+K HY+FNLRD+ ++ GL+ +
Sbjct: 2558 FSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLRDMFKLLLGLLQADR 2617
Query: 2672 ERFQTVAQMVRVWRNECLRVFHDRLISETDKQL 2704
+ ++ +E RVFHDRLI TDK L
Sbjct: 2618 TVVNSKEMAALLFVHEATRVFHDRLIDFTDKSL 2650
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 478 bits (1229), Expect = e-134
Identities = 272/822 (33%), Positives = 456/822 (55%), Gaps = 41/822 (4%)
Query: 3662 LSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFE 3721
+++++ ++ MYQ+SL AF VF+ +++++ PD L +R+ N++D++TFS+Y + GLFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3722 RHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLS 3781
KL + +T +I V ELDF L+ + ++ P +LS Q W + +LS
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAWGAVKVLS 117
Query: 3782 EMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRV 3841
M + F L D+E + W+++ + + E+ +P + N T Q+L +LR R DR+
Sbjct: 118 SM--EEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRM 174
Query: 3842 YRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGF 3901
A+ D+V +G KYV + F FE+S P +P+ FILSPG DP D+ + G+
Sbjct: 175 TYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGY 234
Query: 3902 GGNRLKF--LAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITK-P 3958
N F +++GQGQE VA L+ A +G W++LQN HL+ KWL LEK LE ++
Sbjct: 235 TFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENS 294
Query: 3959 HPDFRLWLTTDPTKG-----FPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCP 4013
HP+FR++++ +P P GIL+ S+K+ EPP G+ N+ + + L+ C
Sbjct: 295 HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCS 354
Query: 4014 HPA-FKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRD 4072
FK +++ L +FHAVV ERRKFG GWN Y FN D + + +L +L + +
Sbjct: 355 RETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFL-----EAN 409
Query: 4073 PRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFD---TFQPFHFFRNKEV 4129
++P+ L+YL GE+MYGG D +DRR+ Y+ E++ + + + P
Sbjct: 410 AKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAP--------- 460
Query: 4130 DYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGE 4189
+ +P + + + I+A +P ++GLHPNAEIG+ TQ + ++ +LELQP+ +
Sbjct: 461 GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQ 520
Query: 4190 S--SSGISRDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVV 4247
+ +G +R++ + + +EI ++ F++ ++ ++ +P VV QE R N L
Sbjct: 521 ARDGAGATREEKVKALLEEILERVTDEFNIPELMAKV-EERTPYIVVAFQECGRMNILTR 579
Query: 4248 RMTKSLAELQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRR 4307
+ +SL EL+ L GE+ M++ ++++ +L+ +P W R A + L W L R
Sbjct: 580 EIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNR 639
Query: 4308 FSQYMLWVTE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDAD 4366
+ W + + PS +WL+G P+S+LTA++Q+T RKN WPLD+ L +TK ++ +
Sbjct: 640 IKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTK-KNRE 698
Query: 4367 EVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTF 4426
E +G ++ GL++EGA WD + G + ++K K L +P++ I I A + ++ +
Sbjct: 699 EFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVY 758
Query: 4427 RTPVYTTSMRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTL 4468
PVY TS R G V+ +L T + S WVL GV L L
Sbjct: 759 SCPVYKTSQR----GPTYVWTFNLKTKENPSKWVLAGVALLL 796
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 197 bits (501), Expect = 2e-49
Identities = 322/1711 (18%), Positives = 653/1711 (38%), Gaps = 255/1711 (14%)
Query: 1224 ERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQ 1283
ER+ EL +A +F T P + + + + I+ LY + EW
Sbjct: 978 ERQFQNTVSDLSELHHAYAIFTEDETPVPLPICGTRPIVQQQRIWHLYRVISENISEWKC 1037
Query: 1284 TLWINLNVQILQEGIEGFLRALRKLPRPVRGLS-VTYYLEAKMKAFKDSIPLLLDLKNEA 1342
+ + + QE EG+L ++ + S V + + F+ +PLL L +
Sbjct: 1038 MAFAKFSPAMAQEKTEGWLTEAARMSTTLELHSPVLQHCMRILGEFRSYLPLLTKLGSLH 1097
Query: 1343 LRDRHWKELMEKTSV-FFEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKE 1401
+ + + L+ + + E TL + L + D +N++ + + ++ ++
Sbjct: 1098 PQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRR 1157
Query: 1402 ILDTWENMKFTV------VKYCKGTQERG-------------------YILGSVDEIIQS 1436
+ WE + + V Y ER +IL + S
Sbjct: 1158 LQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDS 1217
Query: 1437 LDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGGDI 1496
+ ++ L I G + +W + +G ++E+W+ Q+KW++L + I
Sbjct: 1218 IQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVLHEMKI 1277
Query: 1497 RSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSD----------LQNVSEG 1546
+ + +F +D ++ +M ++ DP++ S LQ S
Sbjct: 1278 QFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVE 1337
Query: 1547 LEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKM-YDNIASLRFN 1605
LE SL L FPR FF+SD EL+++L + C + ++ + ++ ++ F
Sbjct: 1338 LEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVSFR 1397
Query: 1606 DGDSGEKLVS---------------AMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRR 1650
+GEK A++ A GE ++ + L + W+ ++ +R
Sbjct: 1398 SCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCLRL 1457
Query: 1651 T-----------------------NRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQV 1687
+L + ++ + +D + + VL A +V
Sbjct: 1458 ALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAEEV 1517
Query: 1688 WWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRI------TMPLSKNDRKKYNTV 1741
W E+E+ + G + + RK+ ++ + + ++P S + +
Sbjct: 1518 VWRAEMEEAL--LEWGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLP-SVRQTSLLSAL 1574
Query: 1742 LIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDR----------------------E 1779
L++ V RDI + + + +F W QL+++
Sbjct: 1575 LVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLS 1634
Query: 1780 PDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKT 1839
P I +F Y YEY+G + + L +R L L AL G GP G GK
Sbjct: 1635 PAACWIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKR 1694
Query: 1840 ETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISS 1899
LA+ALG V+ C ++ + + +G Q GAW ++ +++ +LS +
Sbjct: 1695 AIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQ 1754
Query: 1900 QIQTIRN--ALIHQ----------------LTTFQFEGQEISLDSRMGIFITMNPGYAGR 1941
++ + + A ++Q L + FE +S+ G + + A
Sbjct: 1755 RLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLR---ALS 1811
Query: 1942 TELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLS---- 1997
+ +P ++ L RPV + +PDL+Q+ E+ L G +A +A +++ + L RE +S
Sbjct: 1812 SAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLP 1871
Query: 1998 ------KQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKF-VFEDVP 2050
KQ D +R L K S E+ L+R+ P F + +
Sbjct: 1872 CRLPLLKQILEDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLRS------PLFSILNGLH 1924
Query: 2051 L--FLGLISDLFPGLD---CPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLT 2105
L GL+ LFP + Y V + L++ G P + + Q+ + +
Sbjct: 1925 LHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSR 1984
Query: 2106 RHTTMVVGPTRGGKSVVINTLCQAQTKLGLT----------TKLYILNPKAVSVIELYGI 2155
+++GP GK+ ++L + Q +L ++ L P +S E G
Sbjct: 1985 ASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGW 2044
Query: 2156 LDPTTRDWTDGVLSNIFR---EINKPTDKKERK-------YILFDGDVDALWVENMNSVM 2205
L+ + W G+ + R + N K++ + +I+ DG + W++++ ++
Sbjct: 2045 LEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLL 2102
Query: 2206 DDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWV 2265
+ L+L +G++I LL EV D SP V C +V+ + ++ +
Sbjct: 2103 SELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQ-TWQCILSALM 2161
Query: 2266 NQIPNKVEQYN-----LNSLFEKYVPYLMDVIV-EGIVDGRQAEKLKTIVPQTDLNMVTQ 2319
+P + + LN + E VP + + +G+ Q + + + VT
Sbjct: 2162 ASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVC--AGVAEVTS 2219
Query: 2320 LAKMLDALLEGEI----------EDL---DLLECYFLEALYCSLGASLLEDGRMKFDEYI 2366
+A++L +LL+ + EDL D + F + L S ++ + D+
Sbjct: 2220 MARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVP-DKCR 2278
Query: 2367 KRLASLSTVDTEGVWANPGELPGQL------------------------PTLYDFHFDNK 2402
+ L ++S+ +W LP + ++D H +
Sbjct: 2279 EHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPE 2338
Query: 2403 RNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKT 2462
VP++ +Y+ + + + ++ T R ++++ ++ QPV+ GE+ T K+
Sbjct: 2339 DGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAATGKS 2395
Query: 2463 ATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMD 2522
A + ++ + FSS + + R ++ + + + LL ++
Sbjct: 2396 AFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLLFLLE 2455
Query: 2523 DMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIR-DLGFIAAMGKAGGGRNEV 2581
D+++ D + QP+ G +Y L ++++ + F+A + G +
Sbjct: 2456 DLHLATSDPEKSCQPVLETLRQAMDGTVYAH-STLELQTLQPTVNFLATVTVPGYCERPL 2514
Query: 2582 DPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFH--ESIVAVSGKLTFCTLALYKNI 2639
PR LF+V + ++ +L + I++ F E A++ L ++ ++ +
Sbjct: 2515 CPRLFRLFTVLALESMTQATLLERHVPIIQAWLERFPSVERERALARGLVRASVEAWEAV 2574
Query: 2640 VQDLPPTPSKFHYIFNLRDLSRVFNGLVL--------------TNPERFQTVA------- 2678
P+P HY F+L +S + + L L + E + V+
Sbjct: 2575 CNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHLRRVSGLRGTCL 2634
Query: 2679 -------QMVRVWRNECLRVFHDRLISETDK 2702
+VR+W +E R F DRL S ++
Sbjct: 2635 TVMMATRNVVRLWLHEAQRTFCDRLDSPRER 2665
Score = 121 bits (303), Expect = 2e-26
Identities = 162/725 (22%), Positives = 302/725 (41%), Gaps = 89/725 (12%)
Query: 2783 EHLTRVHRIIRMDRGHALLV-GVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFRED 2841
+H+ R+ R++ R H LL+ G G+G+ + LA+ + C+ L G SE + +
Sbjct: 2870 QHVARLVRVLARPRQHGLLLSGALGTGRHTAITLAS--SICQAHFFHLPSG-SEEAILQC 2926
Query: 2842 LKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQ 2901
L+ G+ ++ + L + L + + TSG P ++E + + I + +
Sbjct: 2927 LRDASWHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPR 2984
Query: 2902 EALKQGMGPAKESVWQYFVNKSANNLHI--VLGMSPVGDTLRTWCRNFPGMVNNTGIDWF 2959
E L KE V Q F + ++LH+ ++G L + + ID +
Sbjct: 2985 ENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRY 3044
Query: 2960 MPWPPQALHAVAKSFLGYNPMIPAEN-----------IENVVKHVVLVHQSVDHYSQQFL 3008
PW AL VA+ L +P ++ I +V K + L+H S HY +
Sbjct: 3045 EPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLC 3104
Query: 3009 QKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIA-QCKRLDGGLDKLKEATIQLDELNQK 3067
L VTPK +LDF++T+ +L ++T I + +R+ L+ L+ +
Sbjct: 3105 PALP---LVTPKTFLDFLDTFL-MLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANL 3160
Query: 3068 LAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETT 3127
+ + + L + + +++ E+ K L +++ E Q +I + +
Sbjct: 3161 IFDLEQQLKDSGKSLSMFQQQL-------EQSKLLYKQQLEECRHQENLIENLARQRDAL 3213
Query: 3128 LAEVMPILEA---AKLE-LQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKT 3183
A+ LE A LE L +L +D EIRS+ PP+ V V + + + + E W +
Sbjct: 3214 QAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDLF-HHETGWAS 3272
Query: 3184 AKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEA 3243
AK ++ +F + L+ + IT S++ + +LK + AVS+ + ++ A
Sbjct: 3273 AKQLLCTEDFYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAWLWA 3332
Query: 3244 VMGYCDVFREIKPKREKVARLE--------RNFYLTKRELERIQNELAAIQKELETLGAK 3295
V+ Y P + ++E R Y + E +++ L A+ K +E A
Sbjct: 3333 VLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNL-ALAKMVEDAQAS 3391
Query: 3296 YEA---AILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDC 3352
+ + + Q Q M+ L+ + W L +L R + + GD
Sbjct: 3392 HNCVAKTLSQAQCGQYHKWPMKAALLTPMR----------AWTTQLQKLKGRCMTVFGDT 3441
Query: 3353 LLCAAFLSYEGAFTWEFRDEMVNR-----------IWQNDI---LERE------------ 3386
LLC+A + Y G F R E+++ + +D+ L+R+
Sbjct: 3442 LLCSAAIIYLGPFPPLRRQELLDEWLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPL 3501
Query: 3387 IPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTT-----RASRFPLCIDPQQQ 3441
+ PF + SLL+ + E +W P + + G+L + R+PL +DP +
Sbjct: 3502 LATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNE 3561
Query: 3442 ALNWI 3446
AL W+
Sbjct: 3562 ALIWL 3566
Score = 102 bits (254), Expect = 9e-21
Identities = 201/926 (21%), Positives = 340/926 (36%), Gaps = 104/926 (11%)
Query: 3455 LRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDK 3514
L V S DP+ QL+ + G P L +V+ + E+ + Q Q L
Sbjct: 3664 LSVLSGADPELGSQLQEAAACGLPVLLTNVELGLG------CEELQWLLQREQ---LSPP 3714
Query: 3515 EVDYDSNFRLYLNTKLANPRYSPSVFGKAM-----VINYTVTLKGLEDQLLSVLVAYERR 3569
+V F LYL+T L+ V G + V++ + ++ LE+Q+L ++ E
Sbjct: 3715 QVQ--PGFCLYLSTTLSLCAME-KVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYP 3771
Query: 3570 ELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSE 3629
ELE + + L + ++ E+ LL L + + + K ++
Sbjct: 3772 ELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRA 3831
Query: 3630 KLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKK 3689
+ E L L YRP G + LS++ + ++ S +L V + +L
Sbjct: 3832 HCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDS 3891
Query: 3690 SLPDSI-----LMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQ 3744
P I L L + LT + T L L + + QA G+ +
Sbjct: 3892 MKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKASE 3951
Query: 3745 EELDFFLKGNISLEKSKRKKPC------AWLSDQGWEDIILLSEMFSDNFGQLPDDVENN 3798
E G + + KP AWL + W + +L + F L + +
Sbjct: 3952 LERLALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELL--PPFVGLCASLAGH 4009
Query: 3799 QTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMG---- 3854
+ WQ + L S P P ++ QKL++ R R + + A+ D+ T +G
Sbjct: 4010 SSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLD 4069
Query: 3855 EKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPA------TDLMKLAERSGFGGNRLKF 3908
E P M F+ S P++ +L P P+ T + KLA + G +L+
Sbjct: 4070 ENTYAPTMP-----FKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQLQV 4124
Query: 3909 LAMGQ---GQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSL------------- 3952
+A+G V + L A+ G WL+L NCHL+ W K+L + L
Sbjct: 4125 IALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADL 4184
Query: 3953 -----------ERITKPHPDFRLWL--TTDPTKGFPIGILQKSLKVVTEPPNGLKL-NMR 3998
++ H DFRLWL + + P + Q S+ V L+L ++
Sbjct: 4185 ESEQLLDQPESRNVSTVHRDFRLWLIVPAESSASLPAVLTQHSMPVFWN--QSLELGHVL 4242
Query: 3999 ATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCME 4058
+++ ++L P PL+ H ++ R+ +G + +
Sbjct: 4243 IDSVELAQQVLYMQPPTQALPLL----LLHGLLLHRQLYGT---RLQAHRGRWSQVTLTQ 4295
Query: 4059 ILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTF 4118
+L T +PR +++ L V YGG D+ DR L L
Sbjct: 4296 VLQTQDQLWASLSNPR---AAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWV 4352
Query: 4119 QPFHFFRNKEVDYKIPVGDEKEKFVEA---IEALPLANTPEVFGLHPNAEIGYYTQAARD 4175
QP +P E + E + LP P + GL + + +R
Sbjct: 4353 QPHTPQSLLATLMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRA 4412
Query: 4176 MWAHLLELQP-QTGESSSGIS-RDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSV 4233
+ + L P ES G + + Q ++ ++ + DL R +P SV
Sbjct: 4413 LLSALQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSV 4472
Query: 4234 -----------VLLQELERFNKLVVRMTKSLAELQRALAGEVGM-SNELDDVARSLFIGH 4281
VL E ++LV + + L L + L G S VA +L+ G
Sbjct: 4473 LGPNARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGR 4532
Query: 4282 IPNIWRRLAPDTLKSLGNWMVYFLRR 4307
+P WR AP + +W+ RR
Sbjct: 4533 LPLPWRPHAPAGPQPPWHWLRQLSRR 4558
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 1e-06
Identities = 63/291 (21%), Positives = 122/291 (41%), Gaps = 29/291 (9%)
Query: 3054 LKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
LK+ IQLD+ N L E ++ ++ +A LEE+ E +KLAE++ +E
Sbjct: 1652 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 1711
Query: 3111 EE-------QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD---KSDVTEIRSFAKPP 3160
E QN + +K + E+ L ++ +E A E + + K +T+ A+
Sbjct: 1712 SERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEEL 1771
Query: 3161 KQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTL 3220
K+ Q + MK E K ++ D Q +K K L+ L
Sbjct: 1772 KKEQDTSAHLERMKKNMEQTIKD--------------LQHRLDEAEQIALKGGKKQLQKL 1817
Query: 3221 NTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQN 3280
E+E +A + E+V G R IK + ++N + ++++Q
Sbjct: 1818 EARVRELEGELEA--EQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQL 1875
Query: 3281 ELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSEN 3331
++ A +++ E + + + +K+Q E + E R A+ ++ L +++
Sbjct: 1876 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
Score = 47.0 bits (110), Expect = 4e-04
Identities = 73/336 (21%), Positives = 146/336 (43%), Gaps = 36/336 (10%)
Query: 3033 LDEKTQCNIAQCKRLDGGLDKLKEATIQLD----ELNQKLAEQKIVLAEKSAACEALLEE 3088
L +K + N A+ + L+ L+ + A +++ +L+++L E L E A +E
Sbjct: 1106 LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165
Query: 3089 IAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQK---- 3144
A ++ ++ EE ++ E + + A++ L E + L+ K +L+K
Sbjct: 1166 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSE 1225
Query: 3145 --LDKSDVTE-IRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEID 3201
L+ DVT + K ++ V + + + A+ ++D R+ ++ +
Sbjct: 1226 FKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE 1285
Query: 3202 FDSITQSQVKNIKGLLKTLN----TTTEEMEAVS-------KAGLGMLKFVEAVMGYCDV 3250
+ + Q++ + L+ L + T++ME + KA + +++ CD+
Sbjct: 1286 NGELAR-QLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
Query: 3251 FREIKPKREKVARLERNFYLTKRELE----RIQNELAAIQKELETLGAKYEAAILEKQKL 3306
RE + + E A+ E L+K E R + E AIQ+ E AK + A Q+L
Sbjct: 1345 LRE-QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRL 1399
Query: 3307 QEEAEIMERRLIAADKLISGLGSENIRWLNDLDELM 3342
Q+ E +E A + S L R N++++LM
Sbjct: 1400 QDAEEAVE----AVNAKCSSLEKTKHRLQNEIEDLM 1431
Score = 45.1 bits (105), Expect = 0.002
Identities = 60/309 (19%), Positives = 127/309 (41%), Gaps = 41/309 (13%)
Query: 3052 DKLKEATIQLDELNQKLAEQKIV-------LAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
+KLK+ +++ N K+ +++++ L E A E L EE+ + +KL
Sbjct: 1080 EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRS 1139
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT---EIRSFAKPPK 3161
+ + E+EE ++ +E+A T++ M A+ + + D + T E + A K
Sbjct: 1140 DLSRELEEISE--RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 3162 QVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQS--QVKNIKGLLKT 3219
+V E + + + K K +S +++ D +T + Q+ K L+
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKE--------KSEFKLELDDVTSNMEQIIKAKANLEK 1249
Query: 3220 LNTTTEEMEAVSKAGLGMLKFVEAVMGYCD--------------VFREIKPKREKVARLE 3265
++ T E+ +A +K EA D + R+++ K +++L
Sbjct: 1250 VSRTLED-----QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLT 1304
Query: 3266 RNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLIS 3325
R +++E ++ +L K L ++A + L+E+ E +++S
Sbjct: 1305 RGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1364
Query: 3326 GLGSENIRW 3334
SE +W
Sbjct: 1365 KANSEVAQW 1373
Score = 34.7 bits (78), Expect = 2.2
Identities = 59/268 (22%), Positives = 121/268 (45%), Gaps = 35/268 (13%)
Query: 3060 QLDELNQKLAEQKIVLAEKSAACEAL-LEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIA 3118
++ +L ++L E + E + L +E++ + +A+ E + L E+ + Q +
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 3119 MEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKE 3178
+ KAE E LAE +E AK Q++ S T + + + +V L +K E
Sbjct: 1570 I-KAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV-------LRVKKKME 1621
Query: 3179 LNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGML 3238
+ + +S N + + Q QVK+++ LLK T +++ +A +
Sbjct: 1622 GDLNEMEIQLSHANRMA--------AEAQKQVKSLQSLLK---DTQIQLDDAVRANDDLK 1670
Query: 3239 KFVEAVMGYCDVFR-EIKPKREKVARLERNFYLTKREL----ERIQ----------NELA 3283
+ + V ++ + E++ R V + ER+ L ++EL ER+Q N+
Sbjct: 1671 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKK 1730
Query: 3284 AIQKELETLGAKYEAAILEKQKLQEEAE 3311
++ +L L ++ E A+ E + +E+A+
Sbjct: 1731 KMESDLTQLQSEVEEAVQECRNAEEKAK 1758
Score = 33.5 bits (75), Expect = 4.9
Identities = 63/300 (21%), Positives = 125/300 (41%), Gaps = 38/300 (12%)
Query: 3032 LLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAV 3091
LL EK + ++ D L +A + D+L + + + + E + E L +E +
Sbjct: 882 LLQEKNDLQL----QVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMN---ERLEDEEEM 934
Query: 3092 NTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT 3151
N + +K+KL E++ E+++ + + E TLA+V A + +++ L +
Sbjct: 935 NAELTAKKRKL-EDECSELKK-------DIDDLELTLAKVEKEKHATENKVKNLTEEMAG 986
Query: 3152 EIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVK 3211
AK K+ K +E + + + + + + SL + + QV
Sbjct: 987 LDEIIAKLTKE----------KKALQEAHQQALDDLQVEEDKVNSLSKSKVK--LEQQVD 1034
Query: 3212 NIKGLLKTLNTTTEEMEAVSKAGLGMLKFV-EAVMGYCDVFREIKPKREKVARLERNFYL 3270
+++G L+ ++E + G LK E++M D+ + EK+ + E +
Sbjct: 1035 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM---DLENDKLQLEEKLKKKEFDINQ 1091
Query: 3271 TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSE 3330
++E Q +QK+L+ A+ E +L+EE E +KL S L E
Sbjct: 1092 QNSKIEDEQVLALQLQKKLKENQARIE-------ELEEELEAERTARAKVEKLRSDLSRE 1144
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 53.5 bits (127), Expect = 5e-06
Identities = 98/494 (19%), Positives = 190/494 (38%), Gaps = 88/494 (17%)
Query: 3179 LNWKTAKGVMSDP---------NFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTE---- 3225
+NWK V D N L SL +++ + + + +N+ L + + +
Sbjct: 5 INWKEIMKVDPDDLPRQEELADNLLISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQ 64
Query: 3226 ----EMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTK-----RELE 3276
+E V KAG KF + + KV +LE + + R+
Sbjct: 65 EVELALEEVEKAGEEQAKFENQL-------------KTKVMKLENELEMAQQSAGGRDTR 111
Query: 3277 RIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLN 3336
++NE+ ++K+LE + E E +K ++ E + R A+ S L EN R
Sbjct: 112 FLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKK 171
Query: 3337 DLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRI-----WQNDILEREIPLSQ 3391
++L C + Y+ + ++ +++R +++ + ++ L Q
Sbjct: 172 KNEQL-------------CQDIIDYQKQIDSQ-KETLLSRRGEDSDYRSQLSKKNYELIQ 217
Query: 3392 PFRLESLLTDDVEISRWGSQGLPPD-ELSVQN-GILTTRASRFPLCIDPQQQALNWIKRK 3449
LT+ E +Q + + E SVQ +T +R + ++ +K++
Sbjct: 218 YLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKE 277
Query: 3450 EEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFI 3509
+ L+V D L + +E DP++ V N KV + + +
Sbjct: 278 NDHYQLQVQELTD-----------------LLKSKNEEDDPIMVAV---NAKVEEWKLIL 317
Query: 3510 ILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERR 3569
D E+ L KL N + A N +G++++ + +
Sbjct: 318 SSKDDEIIEYQQMLHNLREKLKNAQLD------ADKSNVMALQQGIQERDSQI------K 365
Query: 3570 ELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSE 3629
L EQ E +E +N +++DL++ L R ST + ++ + TL+ K K E
Sbjct: 366 MLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAER 425
Query: 3630 KLKLAEKTALDIDR 3643
+LAE A + D+
Sbjct: 426 TAELAEADAREKDK 439
Score = 41.6 bits (96), Expect = 0.018
Identities = 66/352 (18%), Positives = 152/352 (43%), Gaps = 34/352 (9%)
Query: 3005 QQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDEL 3064
Q+ L+K R K + + ++ L+ + ++ + K+ L K + ++
Sbjct: 1560 QRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKH 1619
Query: 3065 NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIE------EQNKVIA 3118
+LAE + +AE+ + +LL ++ + E ++++ E K E E ++N
Sbjct: 1620 FIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDE 1679
Query: 3119 MEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKE 3178
++K +AE + ++ +L+ ++ E Q L + + ++ P T+ + +K
Sbjct: 1680 VKKVKAE--VEDLKYLLDQSQKESQCLKSELQAQKEANSRAP--TTTMRNLVERLKSQLA 1735
Query: 3179 LNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGML 3238
L K K + R+L+E+ + ++ + I + T + EA L +
Sbjct: 1736 LKEKQQKALS------RALLELRAEMTAAAEERII--------SATSQKEA----HLNVQ 1777
Query: 3239 KFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEA 3298
+ V+ ++ +++ E + +L+ +K + + L + EL+ Y
Sbjct: 1778 QIVDRHTR--ELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNK 1835
Query: 3299 AILEKQKLQEEAEIMERRLIAADKLISGL-GSENIRWLNDLDELMHRRVKLL 3349
+ EK+++ +E + ++R++ +L SGL G L E + R+VK L
Sbjct: 1836 ILREKEEIDQENDELKRQI---KRLTSGLQGKPLTDNKQSLIEELQRKVKKL 1884
Score = 33.1 bits (74), Expect = 6.4
Identities = 68/324 (20%), Positives = 127/324 (39%), Gaps = 30/324 (9%)
Query: 3031 KLLDEKTQCNIAQCKRLDGGLDKLKEATIQ---------LDELNQKLAEQKIVLAEKS-- 3079
K + EK Q Q K+ G L K A I+ L++L L Q + E
Sbjct: 2138 KKVVEKVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTK 2197
Query: 3080 ------AACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVM- 3132
A E L +E+ T AE K ++A+ +EI + + +E+ AE
Sbjct: 2198 GTEKIIAENERLRKELKKETDAAE-KLRIAKNN-LEILNEKMTVQLEETGKRLQFAESRG 2255
Query: 3133 PILEAAKLELQK---LDKSDVTEIRSFAKP-PKQVQTVCECILIMKGYKELNWKTAKGVM 3188
P LE A + K + + T+++ K+ Q++ + ++K E K K
Sbjct: 2256 PQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNE 2315
Query: 3189 SDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC 3248
++ L + + T+ + +K L+ L +++ + ++ + G
Sbjct: 2316 DLEQQIKILKHVPEGAETE---QGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAE 2372
Query: 3249 DVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQE 3308
+ +EK+ LE ++ E + ++ E+ ++KELE + I E K
Sbjct: 2373 STIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEI-EDLKYNY 2431
Query: 3309 EAEIMERRLI--AADKLISGLGSE 3330
+ E+ + L+ KL LG E
Sbjct: 2432 KEEVKKNILLEEKVKKLSEQLGVE 2455
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 53.1 bits (126), Expect = 6e-06
Identities = 62/291 (21%), Positives = 121/291 (41%), Gaps = 29/291 (9%)
Query: 3054 LKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
LK+ IQLD+ N L E ++ ++ +A LEE+ E +KLAE++ +E
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 1709
Query: 3111 EE-------QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD---KSDVTEIRSFAKPP 3160
E QN + +K + + L+++ +E A E + + K +T+ A+
Sbjct: 1710 SERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEEL 1769
Query: 3161 KQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTL 3220
K+ Q + MK E K ++ D Q +K K L+ L
Sbjct: 1770 KKEQDTSAHLERMKKNMEQTIKD--------------LQHRLDEAEQIALKGGKKQLQKL 1815
Query: 3221 NTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQN 3280
E+E +A + E+V G R IK + +N + ++++Q
Sbjct: 1816 EARVRELENELEA--EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQL 1873
Query: 3281 ELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSEN 3331
++ A +++ E + + + +K+Q E + E R A+ ++ L +++
Sbjct: 1874 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1924
Score = 42.0 bits (97), Expect = 0.014
Identities = 63/304 (20%), Positives = 127/304 (41%), Gaps = 31/304 (10%)
Query: 3052 DKLKEATIQLDELNQKLAEQKIV-------LAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
++LK+ +L+ LN ++ +++ + L E A E L EE+ + +KL
Sbjct: 1078 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 1137
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT---EIRSFAKPPK 3161
+ + E+EE ++ +E+A T++ M A+ + + D + T E + A K
Sbjct: 1138 DLSRELEEISE--RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1195
Query: 3162 QVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIK---GLLK 3218
+V E + + + K K +S +++ D +T + + IK L K
Sbjct: 1196 HADSVAELGEQIDNLQRVKQKLEKE--------KSEFKLELDDVTSNMEQIIKAKANLEK 1247
Query: 3219 TLNTTTEEM-EAVSKA-----GLGMLKFVEAVM--GYCDVFREIKPKREKVARLERNFYL 3270
T ++M E SKA + L A + ++ R++ K +++L R
Sbjct: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLT 1307
Query: 3271 TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSE 3330
++LE ++ +L K L ++A + L+E+ E +++S SE
Sbjct: 1308 YTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367
Query: 3331 NIRW 3334
+W
Sbjct: 1368 VAQW 1371
Score = 37.7 bits (86), Expect = 0.26
Identities = 85/407 (20%), Positives = 172/407 (42%), Gaps = 52/407 (12%)
Query: 3030 SKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEI 3089
S+ LDEK + I+Q R KL T QL++L ++L E+ + A ++ +
Sbjct: 1288 SRQLDEK-EALISQLTR-----GKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSARHDC 1340
Query: 3090 AVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLEL-QKLDKS 3148
+ EE+ + E + + N +A + + ET + LE AK +L Q+L ++
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400
Query: 3149 DVT------EIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDF 3202
+ + S K ++Q E +++ ++ A D + +F
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMV-----DVERSNAAAAALDKK------QRNF 1449
Query: 3203 DSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVF-REIKPKREKV 3261
D I + + L ++ +E ++S + E + + + F RE K +E++
Sbjct: 1450 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1509
Query: 3262 ARLERNFYL---TKRELERIQNELAAIQKELETLGAKYEAAI-LEKQKL--------QEE 3309
+ L T ELE+++ +L A + EL++ + EA++ E+ K+ Q +
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Query: 3310 AEIMERRLIAADKLISGLGSENIRWLNDL-----------DELMHRRVKLLGDCLLCAAF 3358
AEI ER+L D+ + ++R ++ L +E + + K+ GD
Sbjct: 1570 AEI-ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 3359 LSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEI 3405
LS+ E + ++ + Q+ + + +I L R L +++ I
Sbjct: 1629 LSHANRMAAEAQKQV--KSLQSLLKDTQIQLDDAVRANDDLKENIAI 1673
Score = 36.2 bits (82), Expect = 0.75
Identities = 66/320 (20%), Positives = 133/320 (41%), Gaps = 33/320 (10%)
Query: 3041 IAQCKRLDGGLDKLK-EATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEK 3099
I +R+ L+K K E ++LD++ + + A C L +++ + + AEE
Sbjct: 1207 IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEET 1266
Query: 3100 KKLAEE---KAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156
++ + + +++ +N ++ + E E ++++ +L+ L + E+++
Sbjct: 1267 QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326
Query: 3157 AKPPKQVQTVC-ECILIMKGYKELNWKTAK--GVMSDPNF----LRSLMEIDFDSITQSQ 3209
+Q+ +C L+ + Y+E A+ V+S N R+ E D T+
Sbjct: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEEL 1386
Query: 3210 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLE--- 3265
+ K L + L E +EAV+ + K + D+ +++ A L+
Sbjct: 1387 EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ 1446
Query: 3266 RNFYL-----------TKRELERIQNELAAIQKELETLGAKYEAAI-------LEKQKLQ 3307
RNF ++ ELE Q E ++ EL L YE ++ E + LQ
Sbjct: 1447 RNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQ 1506
Query: 3308 EEAEIMERRLIAADKLISGL 3327
EE + +L ++ K I L
Sbjct: 1507 EEISDLTEQLGSSGKTIHEL 1526
Score = 33.5 bits (75), Expect = 4.9
Identities = 61/300 (20%), Positives = 126/300 (42%), Gaps = 38/300 (12%)
Query: 3032 LLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAV 3091
LL EK + ++ D L +A + D+L + + + + E + E L +E +
Sbjct: 880 LLQEKNDLQL----QVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMN---ERLEDEEEM 932
Query: 3092 NTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT 3151
N + +K+KL E++ E++ + + E TLA+V A + +++ L +
Sbjct: 933 NAELTAKKRKL-EDECSELKR-------DIDDLELTLAKVEKEKHATENKVKNLTEEMAG 984
Query: 3152 EIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVK 3211
AK K+ K +E + + + ++ + + +L + + QV
Sbjct: 985 LDEIIAKLTKE----------KKALQEAHQQALDDLQAEEDKVNTLTKAKVK--LEQQVD 1032
Query: 3212 NIKGLLKTLNTTTEEMEAVSKAGLGMLKFV-EAVMGYCDVFREIKPKREKVARLERNFYL 3270
+++G L+ ++E + G LK E++M D+ + + E++ + +
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM---DLENDKQQLDERLKKKDFELNA 1089
Query: 3271 TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSE 3330
+E Q + +QK+L+ L A+ E +L+EE E +KL S L E
Sbjct: 1090 LNARIEDEQALGSQLQKKLKELQARIE-------ELEEELEAERTARAKVEKLRSDLSRE 1142
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 52.4 bits (124), Expect = 1e-05
Identities = 65/325 (20%), Positives = 133/325 (40%), Gaps = 46/325 (14%)
Query: 3051 LDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALL---EEIAVNTAV-----------A 3096
+ K++E + L++ N K ++K ++ ++ A C + L EE A N A
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL 1039
Query: 3097 EEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDK--------- 3147
EE+ K E+ E+E+ + + E + + +AE+ ++ KL+L K ++
Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
Query: 3148 SDVT-----EIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDF 3202
D T ++ + Q+ + E K + K + + + L++ +E
Sbjct: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 3203 DSITQSQ------VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKP 3256
D+ Q + + L K L T+ EA + + + E+
Sbjct: 1160 DTTAAQQELRTKREQEVAELKKALEEETKNHEA---------QIQDMRQRHATALEELSE 1210
Query: 3257 KREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERR 3316
+ E+ R + N K+ LE ELA K L+ + A+ E +++KL + + + +
Sbjct: 1211 QLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEH---KRKKLDAQVQELHAK 1267
Query: 3317 LIAADKLISGLGSENIRWLNDLDEL 3341
+ D+L L + + N+LD +
Sbjct: 1268 VSEGDRLRVELAEKASKLQNELDNV 1292
Score = 42.0 bits (97), Expect = 0.014
Identities = 61/296 (20%), Positives = 119/296 (40%), Gaps = 34/296 (11%)
Query: 3046 RLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEE 3105
+++G L++++ QL E LAEQ E A E + +A EE E
Sbjct: 870 KVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLES 929
Query: 3106 KAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQV-- 3163
+ E EE+N+++ EK + + + ++ L+ + QKL VT K +++
Sbjct: 930 RVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILL 989
Query: 3164 ----------------QTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLME-IDFDSIT 3206
+ EC + +E AK + L E + + T
Sbjct: 990 LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT 1049
Query: 3207 QSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVAR--- 3263
+ +++ K L T ++ A +A + LK + ++ + + +AR
Sbjct: 1050 RQELEKAKRKLDGETTDLQDQIAELQAQIDELKL--------QLAKKEEELQGALARGDD 1101
Query: 3264 --LERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRL 3317
L +N L + + +Q ++A +Q++ E+ A A +K+ L EE E ++ L
Sbjct: 1102 ETLHKNNAL--KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Score = 37.7 bits (86), Expect = 0.26
Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 3569 RELEEQREHLIQETSENKNLLKDLEDSLL---RELATSTGNMLDNVDLVHTLEETKSKAT 3625
R+LEE++ L ++ E + K+LE +L +LA + + D++ + +LEE K K
Sbjct: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
Query: 3626 EVSEKL-KLAEKTALDIDRL 3644
+ +E L + E+ AL D+L
Sbjct: 1399 KDAEALSQRLEEKALAYDKL 1418
Score = 37.4 bits (85), Expect = 0.34
Identities = 73/325 (22%), Positives = 129/325 (39%), Gaps = 52/325 (16%)
Query: 3048 DGGLDKLKEATIQLDELNQ----------KLAEQKIVLAEKSAACEALLEEIAVNTAVAE 3097
+ L ++E Q+ EL + K +QK L+E+ A + LE+ TA +
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
Query: 3098 E-----KKKLAE-EKAMEIEEQNKVIAME--KAEAETTLAEVMPILEAAKLELQKLDK-- 3147
E ++++AE +KA+E E +N ++ + T L E+ LE AK L+K
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Query: 3148 ----SDVTEIRSFAKPPKQVQTVCE--CILIMKGYKELNWKTAKGVMSDPNFLRSLMEID 3201
+D E+ K +QV+ E + +EL+ K ++G
Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEG--------------- 1271
Query: 3202 FDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKV 3261
D + + L L+ + +E K G +KF + ++ + ++
Sbjct: 1272 -DRLRVELAEKASKLQNELDNVSTLLEEAEKKG---IKFAKDAASLESQLQDTQELLQEE 1327
Query: 3262 ARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAAD 3321
R + N R+LE +N L Q+E E LEKQ L ++++ + + D
Sbjct: 1328 TRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN-----LEKQVLALQSQLADTKKKVDD 1382
Query: 3322 KL--ISGLGSENIRWLNDLDELMHR 3344
L I L + L D + L R
Sbjct: 1383 DLGTIESLEEAKKKLLKDAEALSQR 1407
Score = 33.5 bits (75), Expect = 4.9
Identities = 66/310 (21%), Positives = 138/310 (44%), Gaps = 20/310 (6%)
Query: 3026 INTYSKLLDEKTQCNIAQCKRLDGGLDKLK---EATIQL-DELNQKLAEQKIVLAEKSAA 3081
+ T + L+++ Q RL+ + +K E +Q DE N+ E+K +L ++
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNE---EKKRLLIKQVRE 1600
Query: 3082 CEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLE 3141
EA LE+ A+A KK E ++E Q + + E L ++ ++ + E
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 3142 LQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEID 3201
L++ S + K+++++ IL ++ + + + + + L EI
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELAD--EIT 1718
Query: 3202 FDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGML--KFVEAVMGYCDVFREIKPKRE 3259
+ +S + + K L+ EE ++ + +L +F + + + E+ +R
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 3260 KVARLERNFYLTKRELERIQNELAAIQKELE-TLGAKYEAAI--LEKQ--KLQEEAEIME 3314
+ + +++LER EL A +ELE + +K++A I LE + +L+E+ E
Sbjct: 1779 AAQKSDN----ARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 3315 RRLIAADKLI 3324
+ AA+KL+
Sbjct: 1835 KERAAANKLV 1844
Score = 33.5 bits (75), Expect = 4.9
Identities = 49/264 (18%), Positives = 105/264 (39%), Gaps = 20/264 (7%)
Query: 3053 KLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEE 3112
+L+EA DE+ + E + L A L EE+A + ++ +E A EI
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 3113 Q---NKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCEC 3169
+ EK E +A++ LE + ++ L+ F K QV T+
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDR-------FRKTTLQVDTLNAE 1772
Query: 3170 ILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVK-NIKGLLKTLNTTTEEME 3228
+ + + + + + L++ ++ + + +S+ K I L + E++E
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQ-ELEGAVKSKFKATISALEAKIGQLEEQLE 1831
Query: 3229 AVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQK 3287
+K K V ++F +++ +R + K ++E+ + +++
Sbjct: 1832 QEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY-------KEQMEKANARMKQLKR 1884
Query: 3288 ELETLGAKYEAAILEKQKLQEEAE 3311
+LE + A ++KLQ E +
Sbjct: 1885 QLEEAEEEATRANASRRKLQRELD 1908
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.0 bits (123), Expect = 1e-05
Identities = 60/288 (20%), Positives = 121/288 (42%), Gaps = 31/288 (10%)
Query: 3054 LKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
LK+ I LD+ + L EQ ++ ++ +A +EE+ E +K+AE++ ++
Sbjct: 1656 LKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1715
Query: 3111 EE-------QNKVIAMEKAEAETTLA----EVMPILEAAKLELQKLDKSDVTEIRSFAKP 3159
E QN + K + ET ++ E+ IL+ A+ +K K+ +T+ A+
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA-ITDAAMMAEE 1774
Query: 3160 PKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKT 3219
K+ Q + MK E K +++ D Q +K K ++
Sbjct: 1775 LKKEQDTSAHLERMKKNMEQTVKD--------------LQLRLDEAEQLALKGGKKQIQK 1820
Query: 3220 LNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQ 3279
L E+E ++ + EAV G R +K + +N + ++++Q
Sbjct: 1821 LEARVRELEGEVES--EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 3280 NELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGL 3327
++ + +++ E + + + +KLQ E E E R A+ ++ L
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926
Score = 45.1 bits (105), Expect = 0.002
Identities = 83/380 (21%), Positives = 156/380 (41%), Gaps = 56/380 (14%)
Query: 3000 VDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQ--CKRLDGGLDKLKE- 3056
+++ QQ +KL++ + + N SK+ DE+ Q K L +++L+E
Sbjct: 1075 IENEKQQLDEKLKKKEF-------EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 3057 ----------ATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEK 3106
A Q +L+++L E L E A A +E A ++ ++ EE
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 3107 AMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTV 3166
++ E + + A++ L E + L+ K +L+K EI A V+TV
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS---NVETV 1244
Query: 3167 CECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKT----LNT 3222
+ KG E +T + +S+ + + +T +G L+T +
Sbjct: 1245 SKA----KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ-----RGRLQTESGEFSR 1295
Query: 3223 TTEEMEA-VSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLERNFY---LTKRELER 3277
+E EA VS+ G F + + + EIK K L+ + + L + + E
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 3278 IQNELAAIQKELETLGA-------KYEA-AILEKQKLQEEAEIMERRLIAADKLISGLGS 3329
Q A +Q+ L KYE AI ++L+E + + +RL AA++ + + +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 3330 E-------NIRWLNDLDELM 3342
+ R N++++LM
Sbjct: 1416 KCASLEKTKQRLQNEVEDLM 1435
Score = 35.0 bits (79), Expect = 1.7
Identities = 67/306 (21%), Positives = 126/306 (41%), Gaps = 46/306 (15%)
Query: 3067 KLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAE- 3125
K AE + +A + + +E+A + A ++K+L E+ ++E+N + +AEAE
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEA---KRKELEEKMVTLLKEKNDLQLQVQAEAEG 903
Query: 3126 -TTLAEVMPILEAAKLELQKLDK------SDVTEIRSFAKPPKQVQTVCECILIMKGYKE 3178
E L K++L+ K D EI + K+ + EC + K +
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR-KLEDECSELKKDIDD 962
Query: 3179 LNW---KTAKGVMSDPNFLRSLME--IDFDSITQSQVKNIKGLLKTLNTTTEEMEA---- 3229
L K K + N +++L E D K K L + T ++++A
Sbjct: 963 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 3230 ---VSKAGLGMLKFVEAVMGYCDVFREIKPKREKVAR-LERNFYLTKRELERIQNELAAI 3285
++KA + + + V+ + G + ++++ E+ R LE + L + + I+NE +
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082
Query: 3286 QKEL-----------------ETLGAKYEAAILEKQ----KLQEEAEIMERRLIAADKLI 3324
++L + LG + + I E Q +L+EE E A+K
Sbjct: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
Query: 3325 SGLGSE 3330
S L E
Sbjct: 1143 SDLSRE 1148
Score = 33.9 bits (76), Expect = 3.7
Identities = 66/327 (20%), Positives = 126/327 (38%), Gaps = 71/327 (21%)
Query: 3034 DEKTQCNIAQCKR-LDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVN 3092
++K + ++ + KR L+G L +E+ + ++ Q+L E+ L +K L +I
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK---LKKKEFEISNLQSKIEDE 1103
Query: 3093 TAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTE 3152
A+ + +K +E IEE + I E+A AK E Q+ D S E
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASR-------------AKAEKQRSDLS--RE 1148
Query: 3153 IRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLR-----SLMEIDFDSITQ 3207
+ ++ ++ + M +E ++ + + + +L + DS+ +
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
Query: 3208 --SQVKNIKGLLKTLNTTTEEM-----------EAVSKAGLGMLKFVEAVMGYCDVFREI 3254
Q+ N++ + + L EM E VSKA + K + D E+
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE---DQLSEL 1265
Query: 3255 KPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 3314
K K E E +R+ N+L A ++ +LQ E+
Sbjct: 1266 KSKEE--------------EQQRLINDLTA-----------------QRGRLQTESGEFS 1294
Query: 3315 RRLIAADKLISGLGSENIRWLNDLDEL 3341
R+L + L+S L + ++EL
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Score = 33.1 bits (74), Expect = 6.4
Identities = 57/303 (18%), Positives = 128/303 (42%), Gaps = 26/303 (8%)
Query: 3041 IAQCKRLDGGLDKLK-EATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEK 3099
I +R+ L+K K E +++D+L + C L ++++ + EE+
Sbjct: 1213 IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQ 1272
Query: 3100 KKLAEEKAME---IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156
++L + + ++ ++ + + E E ++++ +A ++++L + EI++
Sbjct: 1273 QRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332
Query: 3157 AKPPKQVQTVC-ECILIMKGYKELNWKTAK--GVMSDPNF----LRSLMEIDFDSITQSQ 3209
+Q+ +C L+ + Y+E A+ +S N R+ E D T+
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 3210 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLE--- 3265
+ K L + L E +EAV+ + K + + D+ +++ A L+
Sbjct: 1393 EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452
Query: 3266 RNFYL-----------TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 3314
RNF T ELE Q E ++ EL + YE ++ + + L+ E + ++
Sbjct: 1453 RNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 3315 RRL 3317
+ +
Sbjct: 1513 QEI 1515
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.0 bits (123), Expect = 1e-05
Identities = 60/288 (20%), Positives = 121/288 (42%), Gaps = 31/288 (10%)
Query: 3054 LKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
LK+ I LD+ + L EQ ++ ++ +A +EE+ E +K+AE++ ++
Sbjct: 1656 LKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1715
Query: 3111 EE-------QNKVIAMEKAEAETTLA----EVMPILEAAKLELQKLDKSDVTEIRSFAKP 3159
E QN + K + ET ++ E+ IL+ A+ +K K+ +T+ A+
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA-ITDAAMMAEE 1774
Query: 3160 PKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKT 3219
K+ Q + MK E K +++ D Q +K K ++
Sbjct: 1775 LKKEQDTSAHLERMKKNMEQTVKD--------------LQLRLDEAEQLALKGGKKQIQK 1820
Query: 3220 LNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQ 3279
L E+E ++ + EAV G R +K + +N + ++++Q
Sbjct: 1821 LEARVRELEGEVES--EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 3280 NELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGL 3327
++ + +++ E + + + +KLQ E E E R A+ ++ L
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926
Score = 45.1 bits (105), Expect = 0.002
Identities = 83/380 (21%), Positives = 156/380 (41%), Gaps = 56/380 (14%)
Query: 3000 VDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQ--CKRLDGGLDKLKE- 3056
+++ QQ +KL++ + + N SK+ DE+ Q K L +++L+E
Sbjct: 1075 IENEKQQLDEKLKKKEF-------EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE 1127
Query: 3057 ----------ATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEK 3106
A Q +L+++L E L E A A +E A ++ ++ EE
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 3107 AMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTV 3166
++ E + + A++ L E + L+ K +L+K EI A V+TV
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS---NVETV 1244
Query: 3167 CECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKT----LNT 3222
+ KG E +T + +S+ + + +T +G L+T +
Sbjct: 1245 SKA----KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ-----RGRLQTESGEFSR 1295
Query: 3223 TTEEMEA-VSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLERNFY---LTKRELER 3277
+E EA VS+ G F + + + EIK K L+ + + L + + E
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 3278 IQNELAAIQKELETLGA-------KYEA-AILEKQKLQEEAEIMERRLIAADKLISGLGS 3329
Q A +Q+ L KYE AI ++L+E + + +RL AA++ + + +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 3330 E-------NIRWLNDLDELM 3342
+ R N++++LM
Sbjct: 1416 KCASLEKTKQRLQNEVEDLM 1435
Score = 35.0 bits (79), Expect = 1.7
Identities = 67/306 (21%), Positives = 126/306 (41%), Gaps = 46/306 (15%)
Query: 3067 KLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAE- 3125
K AE + +A + + +E+A + A ++K+L E+ ++E+N + +AEAE
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEA---KRKELEEKMVTLLKEKNDLQLQVQAEAEG 903
Query: 3126 -TTLAEVMPILEAAKLELQKLDK------SDVTEIRSFAKPPKQVQTVCECILIMKGYKE 3178
E L K++L+ K D EI + K+ + EC + K +
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR-KLEDECSELKKDIDD 962
Query: 3179 LNW---KTAKGVMSDPNFLRSLME--IDFDSITQSQVKNIKGLLKTLNTTTEEMEA---- 3229
L K K + N +++L E D K K L + T ++++A
Sbjct: 963 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 3230 ---VSKAGLGMLKFVEAVMGYCDVFREIKPKREKVAR-LERNFYLTKRELERIQNELAAI 3285
++KA + + + V+ + G + ++++ E+ R LE + L + + I+NE +
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL 1082
Query: 3286 QKEL-----------------ETLGAKYEAAILEKQ----KLQEEAEIMERRLIAADKLI 3324
++L + LG + + I E Q +L+EE E A+K
Sbjct: 1083 DEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142
Query: 3325 SGLGSE 3330
S L E
Sbjct: 1143 SDLSRE 1148
Score = 33.9 bits (76), Expect = 3.7
Identities = 66/327 (20%), Positives = 126/327 (38%), Gaps = 71/327 (21%)
Query: 3034 DEKTQCNIAQCKR-LDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVN 3092
++K + ++ + KR L+G L +E+ + ++ Q+L E+ L +K L +I
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEK---LKKKEFEISNLQSKIEDE 1103
Query: 3093 TAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTE 3152
A+ + +K +E IEE + I E+A AK E Q+ D S E
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASR-------------AKAEKQRSDLS--RE 1148
Query: 3153 IRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLR-----SLMEIDFDSITQ 3207
+ ++ ++ + M +E ++ + + + +L + DS+ +
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
Query: 3208 --SQVKNIKGLLKTLNTTTEEM-----------EAVSKAGLGMLKFVEAVMGYCDVFREI 3254
Q+ N++ + + L EM E VSKA + K + D E+
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE---DQLSEL 1265
Query: 3255 KPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 3314
K K E E +R+ N+L A ++ +LQ E+
Sbjct: 1266 KSKEE--------------EQQRLINDLTA-----------------QRGRLQTESGEFS 1294
Query: 3315 RRLIAADKLISGLGSENIRWLNDLDEL 3341
R+L + L+S L + ++EL
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Score = 33.1 bits (74), Expect = 6.4
Identities = 57/303 (18%), Positives = 128/303 (42%), Gaps = 26/303 (8%)
Query: 3041 IAQCKRLDGGLDKLK-EATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEK 3099
I +R+ L+K K E +++D+L + C L ++++ + EE+
Sbjct: 1213 IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQ 1272
Query: 3100 KKLAEEKAME---IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156
++L + + ++ ++ + + E E ++++ +A ++++L + EI++
Sbjct: 1273 QRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332
Query: 3157 AKPPKQVQTVC-ECILIMKGYKELNWKTAK--GVMSDPNF----LRSLMEIDFDSITQSQ 3209
+Q+ +C L+ + Y+E A+ +S N R+ E D T+
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 3210 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLE--- 3265
+ K L + L E +EAV+ + K + + D+ +++ A L+
Sbjct: 1393 EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452
Query: 3266 RNFYL-----------TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 3314
RNF T ELE Q E ++ EL + YE ++ + + L+ E + ++
Sbjct: 1453 RNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Query: 3315 RRL 3317
+ +
Sbjct: 1513 QEI 1515
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 51.2 bits (121), Expect = 2e-05
Identities = 80/378 (21%), Positives = 157/378 (41%), Gaps = 52/378 (13%)
Query: 3000 VDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQ--CKRLDGGLDKLKEA 3057
+++ QQ +KL++ + + +K+ DE+ Q K L +++L+E
Sbjct: 1073 LENDKQQIEEKLKKKEF-------ELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEE 1125
Query: 3058 TIQLDELNQKLAEQKIVLAEKSAACEALLEEI--AVNTAVAEEKKKLAE---------EK 3106
L K+ +Q+ LA + LEE A + + KK+ AE E
Sbjct: 1126 IEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 3107 AMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDV--------TEIRSFAK 3158
++ E + ++A++ L E + L+ K +L+K +KS++ + I + +K
Sbjct: 1186 TLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEK-EKSELKMEIDDMASNIEALSK 1244
Query: 3159 PPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEI----------DFDSITQS 3208
++ C + + + ++ D N ++ ++ + +S+
Sbjct: 1245 SKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQ 1304
Query: 3209 QVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNF 3268
K+ + L + L +ME +KA M +++ CD+ RE + + E+ A+ E
Sbjct: 1305 LTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE-QYEEEQEAKAELQR 1363
Query: 3269 YLTKRELE----RIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLI 3324
L+K E R + E AIQ+ E AK + A Q+LQE E E A+
Sbjct: 1364 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA----QRLQEAEENTE----TANSKC 1415
Query: 3325 SGLGSENIRWLNDLDELM 3342
+ L R ++++LM
Sbjct: 1416 ASLEKTKQRLQGEVEDLM 1433
Score = 42.7 bits (99), Expect = 0.008
Identities = 52/292 (17%), Positives = 123/292 (42%), Gaps = 29/292 (9%)
Query: 3053 KLKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAME 3109
+LK++ + LD+ N+ L EQ ++ ++ LEE+ V E ++L+E++ ++
Sbjct: 1653 QLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLD 1712
Query: 3110 -------IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD---KSDVTEIRSFAKP 3159
+ QN + K + E +A+ +E + E + + K +T+ A+
Sbjct: 1713 ASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEE 1772
Query: 3160 PKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKT 3219
K+ Q + MK K + + D ++ D Q +K K ++
Sbjct: 1773 LKKEQDTSAHLERMK-------KNLEQTVKD-------LQHRLDEAEQLALKGGKKQIQK 1818
Query: 3220 LNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQ 3279
L E+E ++ + + EA+ G R++K + +N + ++++Q
Sbjct: 1819 LENRVRELE--NELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQ 1876
Query: 3280 NELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSEN 3331
++ + +++ E + + +++Q E E R A+ ++ L +++
Sbjct: 1877 AKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKS 1928
Score = 36.2 bits (82), Expect = 0.75
Identities = 58/314 (18%), Positives = 129/314 (41%), Gaps = 26/314 (8%)
Query: 3041 IAQCKRLDGGLDKLK-EATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEK 3099
I +R+ L+K K E +++D++ + + C + ++ + A E++
Sbjct: 1211 IDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQ 1270
Query: 3100 KKLAEEKAME---IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSF 3156
+L + M+ ++ QN ++ E E+ ++++ +A +L++L + E ++
Sbjct: 1271 TQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAK 1330
Query: 3157 AKPPKQVQTVC-ECILIMKGYKELNWKTAK------GVMSDPNFLRSLMEIDFDSITQSQ 3209
+Q+ +C L+ + Y+E A+ S+ R+ E D T+
Sbjct: 1331 NAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEEL 1390
Query: 3210 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLE--- 3265
+ K L + L E E + + K + + G D+ R+++ A L+
Sbjct: 1391 EEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQ 1450
Query: 3266 RNFYL-----------TKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 3314
RNF ++ ELE Q E ++ EL + YE + + + L+ E + ++
Sbjct: 1451 RNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510
Query: 3315 RRLIAADKLISGLG 3328
+ + I+ G
Sbjct: 1511 EEISDLTEQIAETG 1524
Score = 34.7 bits (78), Expect = 2.2
Identities = 54/293 (18%), Positives = 125/293 (42%), Gaps = 26/293 (8%)
Query: 3031 KLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVL-AEKSAACEALLEEI 3089
K L+EK + + L + E + +E + L + KI+L A+ E L EE
Sbjct: 875 KELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEE 934
Query: 3090 AVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSD 3149
+N+ + +K+ L E++ + + + E TL +V A + +++ L +
Sbjct: 935 EMNSELVAKKRNL--------EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEM 986
Query: 3150 VTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQ 3209
+ +K K+ K +E + +T + + + + L++I ++ + Q
Sbjct: 987 TALEENISKLTKE----------KKSLQEAHQQTLDDLQVEEDKVNGLIKI--NAKLEQQ 1034
Query: 3210 VKNIKGLLKTLNTTTEEMEAVSKAGLGMLKF-VEAVMGY----CDVFREIKPKREKVARL 3264
+++G L+ ++E + G LK E++M + ++K K ++++L
Sbjct: 1035 TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQL 1094
Query: 3265 ERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRL 3317
+ + + Q ++ +Q +E L + EA + K++++ + R L
Sbjct: 1095 QAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLAREL 1147
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 51.2 bits (121), Expect = 2e-05
Identities = 58/287 (20%), Positives = 118/287 (41%), Gaps = 29/287 (10%)
Query: 3054 LKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
LK+ + LD+ L EQ ++ ++ +A +EE+ + E +K+AE++ ++
Sbjct: 1654 LKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDA 1713
Query: 3111 EE-------QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD---KSDVTEIRSFAKPP 3160
E QN + K + ET ++++ +E E + + K +T+ A+
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773
Query: 3161 KQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTL 3220
K+ Q + MK E K +++ D Q +K K ++ L
Sbjct: 1774 KKEQDTSAHLERMKKNMEQTVKD--------------LQLRLDEAEQLALKGGKKQIQKL 1819
Query: 3221 NTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQN 3280
E+E S+ VEAV G R +K + +N + ++++Q
Sbjct: 1820 EARVRELE--SEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877
Query: 3281 ELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGL 3327
++ A +++ E + + + +KLQ E E + R A+ ++ L
Sbjct: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKL 1924
Score = 42.0 bits (97), Expect = 0.014
Identities = 63/302 (20%), Positives = 124/302 (41%), Gaps = 27/302 (8%)
Query: 3052 DKLKEATIQLDELNQKLAEQKIV-------LAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
+KLK+ ++ L K+ +++ + + E A E L EEI A + +K
Sbjct: 1082 EKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS 1141
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT---EIRSFAKPPK 3161
+ + E+EE ++ +E+A T+ M A+ + + D + T E + A K
Sbjct: 1142 DLSRELEEISE--RLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKK 1199
Query: 3162 QVQTVCEC---ILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVK-NIKGLL 3217
+V E I ++ K+ K + + N L S ME T S+ K N + +
Sbjct: 1200 HADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNME------TVSKAKANFEKMC 1253
Query: 3218 KTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-----DVFREIKPKREKVARLERNFYLTK 3272
+TL E++ + ++ + A + R++ K V++L R
Sbjct: 1254 RTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFT 1313
Query: 3273 RELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENI 3332
+++E ++ +L K TL ++A + L+E+ E + + +S SE
Sbjct: 1314 QQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVA 1373
Query: 3333 RW 3334
+W
Sbjct: 1374 QW 1375
Score = 39.3 bits (90), Expect = 0.089
Identities = 64/349 (18%), Positives = 147/349 (42%), Gaps = 47/349 (13%)
Query: 3029 YSKLLDEKTQCNIAQCKRLDGGLDKLKEA-TIQLDELNQKLAEQKIVLAEKSAACEALLE 3087
+S+ LDEK A +L G K+A T Q++EL ++L E+ + + A ++
Sbjct: 1291 FSRQLDEKD----AMVSQLSRG----KQAFTQQIEELKRQLEEETKAKSTLAHALQSARH 1342
Query: 3088 EIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLEL-QKLD 3146
+ + EE+++ E + + N +A + + ET + LE AK +L Q+L
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1402
Query: 3147 KSDV------TEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEI 3200
++ ++ S K +++Q E ++I ++ A + D +
Sbjct: 1403 DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMI-----DVERSNAACIALDKK------QR 1451
Query: 3201 DFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFR-------- 3252
+FD + + + L + +E ++S + E + + + +
Sbjct: 1452 NFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQ 1511
Query: 3253 EIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQ-------- 3304
EI E++A ++ + ELE+++ +L + EL+T + EA++ ++
Sbjct: 1512 EISDLTEQIAEGGKHIH----ELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQL 1567
Query: 3305 KLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCL 3353
+L + ++R++ D+ + L ++R + + + ++ D L
Sbjct: 1568 ELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDAL 1616
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 50.8 bits (120), Expect = 3e-05
Identities = 61/296 (20%), Positives = 122/296 (41%), Gaps = 29/296 (9%)
Query: 3045 KRLDGGLDKLKEATIQLDEL---NQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKK 3101
K L +LK+ + LD+ + L EQ ++ ++ +A +EE+ E +K
Sbjct: 1642 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARK 1701
Query: 3102 LAEEKAMEIEE-------QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD---KSDVT 3151
LAE++ ++ E QN + K + ET L ++ +E A + + + K +T
Sbjct: 1702 LAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAIT 1761
Query: 3152 EIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVK 3211
+ A+ K+ Q + MK K + + D ++ D Q +K
Sbjct: 1762 DAAMMAEELKKEQDTSAHLERMK-------KNLEQTVKD-------LQHRLDEAEQLALK 1807
Query: 3212 NIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLT 3271
K ++ L T E+E + K E+V G R +K + +N
Sbjct: 1808 GGKKQIQKLETRIRELEFELEG--EQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRL 1865
Query: 3272 KRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGL 3327
+ ++++Q ++ + +++ E + A + + +K Q E E E R A+ ++ L
Sbjct: 1866 QDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKL 1921
Score = 39.3 bits (90), Expect = 0.089
Identities = 63/290 (21%), Positives = 125/290 (43%), Gaps = 33/290 (11%)
Query: 3029 YSKLLDE-KTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLE 3087
+ K+L E KT+C +Q + L+ L + + + +L +L E L + L +
Sbjct: 1450 FDKVLAEWKTKCEESQAE-LEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQ 1508
Query: 3088 EIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDK 3147
EIA T E K E +E+ K I +EKA+ + L E LE + ++ ++ +
Sbjct: 1509 EIADLTEQIAENGKTIHE----LEKSRKQIELEKADIQLALEEAEAALEHEEAKILRI-Q 1563
Query: 3148 SDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQ 3207
++T+++S + +++ E I +K + +T ++S ++ + S +
Sbjct: 1564 LELTQVKS--EIDRKIAEKDEEIEQLKRNYQRTVET----------MQSALDAEVRSRNE 1611
Query: 3208 SQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC--------DVFREIKPKRE 3259
+ ++ K + LN ++ ++ LK + +V G D R + +E
Sbjct: 1612 A-IRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKE 1670
Query: 3260 KVARLERNFYLTKRELERI-----QNELAAIQKELETLGAKYEAAILEKQ 3304
++A +ER L + E+E + Q E A E E L + +L Q
Sbjct: 1671 QLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQ 1720
Score = 38.5 bits (88), Expect = 0.15
Identities = 59/286 (20%), Positives = 115/286 (40%), Gaps = 44/286 (15%)
Query: 3052 DKLKEATIQLDELNQKLAEQKIV-------LAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
++LK+ + +L K+ +++ + + E A E L EEI A + +K
Sbjct: 1079 ERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS 1138
Query: 3105 EKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT---EIRSFAKPPK 3161
+ A E+EE ++ + E +T E+ EA L+L++ D + T E A K
Sbjct: 1139 DYARELEELSERLE-EAGGVTSTQIELNKKREAEFLKLRR-DLEEATLQHEAMVAALRKK 1196
Query: 3162 QVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLN 3221
+V E + + + K K +S +++ D ++ S
Sbjct: 1197 HADSVAELGEQIDNLQRVKQKLEKE--------KSEFKLEIDDLSSS------------- 1235
Query: 3222 TTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNE 3281
ME+VSK+ + K + D E + K E++ +R+ + R+Q E
Sbjct: 1236 -----MESVSKSKANLEKICRTLE---DQLSEARGKNEEI---QRSLSELTTQKSRLQTE 1284
Query: 3282 LAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGL 3327
+ ++LE + KQ ++ E ++R+L +K + L
Sbjct: 1285 AGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 1330
Score = 33.9 bits (76), Expect = 3.7
Identities = 68/333 (20%), Positives = 133/333 (39%), Gaps = 51/333 (15%)
Query: 3053 KLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEE 3112
+L E L + QKL ++K + + +E ++ + A E+ + E++ E
Sbjct: 1203 ELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARG 1262
Query: 3113 QNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTV------ 3166
+N+ I +E T + + EA +L Q +K + S +K QT
Sbjct: 1263 KNEEIQRSLSELTTQKSRLQT--EAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
Query: 3167 ------------------CECILIMKGYKELNWKTAK------GVMSDPNFLRSLMEIDF 3202
+C L+ + Y+E A+ S+ R+ E D
Sbjct: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
Query: 3203 DSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKV 3261
T+ + K L + L + E++EAV+ + K + + G D+ +++
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 3262 ARLE---RNF------YLTK-----RELERIQNELAAIQKELETLGAKYEAAILEKQKLQ 3307
A L+ RNF + TK ELE E ++ EL L YE A+ + + ++
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 3308 EEAEIMERRLIAADKLISGLGSENIRWLNDLDE 3340
E + +E+ + + I +EN + +++L++
Sbjct: 1501 RENKNLEQEIADLTEQI----AENGKTIHELEK 1529
Score = 32.7 bits (73), Expect = 8.3
Identities = 55/266 (20%), Positives = 111/266 (41%), Gaps = 32/266 (12%)
Query: 3067 KLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAET 3126
K AE + +A + +E+A + A ++K+L E+ ++E+N + +AE+E
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEA---KRKELEEKLVTLVQEKNDLQLQVQAESEN 898
Query: 3127 TL--AEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTA 3184
L E L AK +L+ + + E+ A+ +++ + K E
Sbjct: 899 LLDAEERCDQLIKAKFQLE----AKIKEVTERAEDEEEINAE---LTAKKRKLEDECSEL 951
Query: 3185 KGVMSDPNFLRSLMEIDFDSITQSQVKN----IKGLLKTLNTTTEEMEAVSKAGLGMLKF 3240
K + D + +E + T+++VKN + GL +T+ T E +A+ +A L
Sbjct: 952 KKDIDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
Query: 3241 VEAVMGYCDVFREIKPKREKVAR---------------LERNFYLTKRELERIQNELAAI 3285
++A + + K K E+ LERN + +L+ Q + +
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
Query: 3286 QKELETLGAKYEAAILEKQKLQEEAE 3311
+ + + L + + E +LQ + E
Sbjct: 1071 ENDKQQLDERLKKKDFEYCQLQSKVE 1096
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 50.4 bits (119), Expect = 4e-05
Identities = 58/283 (20%), Positives = 119/283 (42%), Gaps = 19/283 (6%)
Query: 3042 AQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKK 3101
AQ K G D+ + +L E Q L + +LA + A LE+ + +AE++
Sbjct: 1697 AQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELL 1756
Query: 3102 LAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAA---KLELQKLDKSDVTEIRSFAK 3158
A E+ + QN + +K + E LA++ +E A + E ++ K +T+ A+
Sbjct: 1757 EATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAE 1816
Query: 3159 PPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLK 3218
K+ Q + MK KT + + + ++ + Q+ ++ K ++
Sbjct: 1817 ELKKEQDTSAHLERMK-------KTLEQTVRE-------LQARLEEAEQAALRGGKKQVQ 1862
Query: 3219 TLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERI 3278
L E+EA A K EA+ G R +K + +N + ++++
Sbjct: 1863 KLEAKVRELEAELDA--EQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKL 1920
Query: 3279 QNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAAD 3321
Q+++ + +++ E + + + +K Q E + E R A+
Sbjct: 1921 QSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963
Score = 46.2 bits (108), Expect = 7e-04
Identities = 65/312 (20%), Positives = 134/312 (42%), Gaps = 31/312 (9%)
Query: 3032 LLDEKTQCN--IAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEI 3089
L D + +C+ I +L+G + +L E +E+N LA ++ L ++ + ++++
Sbjct: 947 LADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDL 1006
Query: 3090 AVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKL--DK 3147
+ A AE++K+ E K + E+ + A++++ A T E + EA + L L ++
Sbjct: 1007 KLTLAKAEKEKQATENKVKNLTEE--MAALDESVARLT-KEKKALQEAHQQALGDLQAEE 1063
Query: 3148 SDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQ 3207
V+ + +Q EC L + ++ + AK + L D Q
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123
Query: 3208 SQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYC-DVFREIKPKREKVARLER 3266
+ +K L+ + +E G M K ++ + ++ E++ +R AR+E+
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183
Query: 3267 NFYLTKRELERI---------------------QNELAAIQKELETLGAKYEA--AILEK 3303
RELE + + EL +++ELE ++EA A L +
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243
Query: 3304 QKLQEEAEIMER 3315
++ + AE+ E+
Sbjct: 1244 KQAEGAAELGEQ 1255
Score = 41.2 bits (95), Expect = 0.023
Identities = 78/329 (23%), Positives = 126/329 (38%), Gaps = 40/329 (12%)
Query: 3052 DKLKEATIQLDELNQKLAE---QKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAM 3108
D+L EA I+++EL ++LA+ Q+ L +S LLEE + K LA +
Sbjct: 1303 DQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE 1362
Query: 3109 EIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCE 3168
E+ Q + E+++A++ LA + L + D +R + + Q +
Sbjct: 1363 ELRRQLE----EESKAKSALAHAVQAL-----------RHDCDLLREQHEEEAEAQAELQ 1407
Query: 3169 CILIMKGYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEME 3228
+L + W RS E D T+ + K L L E +E
Sbjct: 1408 RLLSKANAEVAQW-------------RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVE 1454
Query: 3229 AVS-------KAGLGMLKFVEAVMGYCDVFREIKPKREKVAR-LERNFYLTKRELERIQN 3280
A + KA L + E V + +K R LER +R+ E +Q
Sbjct: 1455 AANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQR 1514
Query: 3281 ELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDE 3340
EL A Q+E LG + ++ E E ++R + IS L + + E
Sbjct: 1515 ELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQE 1574
Query: 3341 LMHRRVKLLGD-CLLCAAFLSYEGAFTWE 3368
L + L G+ + AA EGA E
Sbjct: 1575 LEKTKKALEGEKSEIQAALEEAEGALELE 1603
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 49.7 bits (117), Expect = 7e-05
Identities = 70/375 (18%), Positives = 162/375 (43%), Gaps = 39/375 (10%)
Query: 2986 IENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDF-INTYSKLLDEKTQCNIAQC 3044
+EN K + L++ V+ Q +Q+L++SN++ + + + + + L++K +I
Sbjct: 906 LENKEKELQLLNDKVET-EQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISL 964
Query: 3045 KRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAE 3104
+ + +++L + L E+N L ++K+ L +KS + ++E +++E + +
Sbjct: 965 NKRE--IEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDER--EKSISELSDQYKQ 1020
Query: 3105 EKAM-------------EIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVT 3151
EK + ++ ++ K + ++ E L E + E K EL++L ++
Sbjct: 1021 EKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAK 1080
Query: 3152 EIR------SFAKPPKQ-----VQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLMEI 3200
E + +FA+ Q ++TV + + + N K+ G + +
Sbjct: 1081 EHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQN 1140
Query: 3201 DFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREK 3260
++ + L+K + T E S+ +K E+ C+ ++ + ++
Sbjct: 1141 KMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKE 1200
Query: 3261 VARLERNFYLTKRE---------LERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAE 3311
++ N L + E L+ + E +Q EL+T+ E + L+ + QE +
Sbjct: 1201 ISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISG 1260
Query: 3312 IMERRLIAADKLISG 3326
+ + + A +K ISG
Sbjct: 1261 LKDCEIDAEEKYISG 1275
Score = 47.4 bits (111), Expect = 3e-04
Identities = 67/330 (20%), Positives = 128/330 (38%), Gaps = 73/330 (22%)
Query: 3033 LDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAAC---------- 3082
L+E+ ++ +L G LD + + T LD+L++K+ E+ L + C
Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAE 2008
Query: 3083 ----EALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEV-----MP 3133
LL+ ++ + + + K +EK +E+ ++ +++ K E E +A++ +
Sbjct: 2009 VKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 3134 ILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNF 3193
+ E+ L+ +L +SD ++ V E L+ KG L
Sbjct: 2069 VKESESLQA-RLSESDYEKLN--------VSKALEAALVEKGEFALRL------------ 2107
Query: 3194 LRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFRE 3253
S TQ +V ++ ++ L E E LK E RE
Sbjct: 2108 ----------SSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERE---------RE 2148
Query: 3254 IKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAIL------------ 3301
++KV LER +++ E + + + E+ETL + E
Sbjct: 2149 NDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTL 2208
Query: 3302 --EKQKLQEEAEIMERRLIAADKLISGLGS 3329
EK+ L ++ + + +L DKL+S S
Sbjct: 2209 RSEKENLTKQIQEKQGQLSELDKLLSSFKS 2238
Score = 47.0 bits (110), Expect = 4e-04
Identities = 73/329 (22%), Positives = 139/329 (42%), Gaps = 27/329 (8%)
Query: 3052 DKLKEATIQLDELNQKLA--EQKIVLAEKSAACEALLEEIA---VNTAVAEEKKKLAEEK 3106
D+L T Q D+ + K EQK+ + +C+ E A + + E++K+ EE
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEEL 400
Query: 3107 AME---IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQV 3163
+ + + ++ KA L + + + EL KL S ++ + + KQ
Sbjct: 401 SRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLT-SVKQQLENNLEEFKQK 459
Query: 3164 QTVCECILIMKGYKELNWKTAKGVMS-DPNFLRSLMEIDFDSIT--QSQVKNIKGLLKTL 3220
E KE + + M + N L+S E + ++++KNIK L
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Query: 3221 NTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLER-----NFYLTKRE- 3274
EEM+A + + ML+ ++ + + ++ + VA LE+ L KRE
Sbjct: 520 QNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREH 579
Query: 3275 -LERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIR 3333
+E++ ++L+ +KE + L + E E ++L+EE + +KL++ + SE
Sbjct: 580 HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEK-- 637
Query: 3334 WLNDLDELMHRRVKLLGDCLLCAAFLSYE 3362
E + ++ L CL S+E
Sbjct: 638 ------ENLQSKINHLETCLKTQQIKSHE 660
Score = 42.7 bits (99), Expect = 0.008
Identities = 50/239 (20%), Positives = 110/239 (46%), Gaps = 21/239 (8%)
Query: 3104 EEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKP-PKQ 3162
+EK + ++ ++K++ + + + ++E+ +++ K E L T +R+F K+
Sbjct: 1408 QEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLS----TNLRNFQGDLVKE 1463
Query: 3163 VQTVCECILIMKGYKE-LNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLN 3221
+Q E L+ + ++ + D +F R+L+E D S + N++G +
Sbjct: 1464 MQLGLEEGLVPSLSSSCVPDSSSLSSLGDSSFYRALLEQTGD---MSLLSNLEGAVSANQ 1520
Query: 3222 TTTEEMEAVS---------KAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTK 3272
+ +E+ S + K VE + C+V+R+ K E+ ++E +
Sbjct: 1521 CSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLCEVYRQSLEKLEE--KMESQGIMKN 1578
Query: 3273 RELERIQNELAAIQKELETLGAKYEAAILE-KQKLQEEAEIMERRLIAADKLISGLGSE 3330
+E++ ++ L++ ++EL+ L +Y + + +QKL ME +L A K L E
Sbjct: 1579 KEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLE 1637
Score = 42.7 bits (99), Expect = 0.008
Identities = 72/330 (21%), Positives = 140/330 (42%), Gaps = 43/330 (13%)
Query: 3034 DEKTQCNIAQ-CKRLDGGLDKLK------EATIQLDELNQKLAEQKIVLAEKSAACEALL 3086
DEK Q +IA+ K + D LK E +Q+ E NQ+L I+ AE S +A +
Sbjct: 2131 DEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV---ILDAENS---KAEV 2184
Query: 3087 EEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLD 3146
E + K+ E + + + + + + E + L+E+ +L + K L++ +
Sbjct: 2185 ETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE 2244
Query: 3147 KSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGVMSDPNFLRSLME-IDFDSI 3205
++++ +I+ +K + ++ KELN A + D +++ + +D
Sbjct: 2245 QAEI-QIKEESKTAVE--------MLQNQLKELNEAVA-ALCGDQEIMKATEQSLDPPIE 2294
Query: 3206 TQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLE 3265
+ Q++N ++ +EA K L +L+ ++ + D+ + +V LE
Sbjct: 2295 EEHQLRN------SIEKLRARLEADEKKQLCVLQQLKESEHHADLLKG------RVENLE 2342
Query: 3266 RNFYLTKRELERIQNELAAIQKELETLGAKYEAAI-------LEKQKLQEEAEIMERRLI 3318
R + + E E + E+ETL AK E L+ ++ E E + L
Sbjct: 2343 RELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQ 2402
Query: 3319 AADKLISGLGSENIRWLNDLDELMHRRVKL 3348
+ IS L N + N L E +V++
Sbjct: 2403 KEQERISELEIINSSFENILQEKEQEKVQM 2432
Score = 35.4 bits (80), Expect = 1.3
Identities = 69/325 (21%), Positives = 133/325 (40%), Gaps = 72/325 (22%)
Query: 3034 DEKTQCNIAQCKRLDGGLDKLK-------EATIQLDELNQKLAEQKIVLAEK----SAAC 3082
D K + + + K LD L + EA I+L+++ +L ++ L+EK S
Sbjct: 1794 DRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDH 1853
Query: 3083 EALLEEIAVNTAVAEEKKKLAE-------------------EKAMEIEEQNKVIAMEKAE 3123
+ LL+ + + + + + A+ E+ +++E + I EKA
Sbjct: 1854 QELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKAS 1913
Query: 3124 AETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKT 3183
E + LE + E L+K + + Q V C+ +EL+
Sbjct: 1914 IEHEALYLEADLEVVQTEKLCLEKDN-----------ENKQKVIVCL-----EEELS--- 1954
Query: 3184 AKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEA 3243
V S+ N LR E+D S + + L + + T+E+E+ L ++ EA
Sbjct: 1955 --VVTSERNQLRG--ELDTMS---KKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEA 2007
Query: 3244 VMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLG-----AKYEA 3298
E+K K E + L + ++ +Q +L +++K+ + L + +
Sbjct: 2008 ---------EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQI 2058
Query: 3299 AILEKQK--LQEEAEIMERRLIAAD 3321
A L K+K L +E+E ++ RL +D
Sbjct: 2059 AQLNKEKELLVKESESLQARLSESD 2083
Score = 33.1 bits (74), Expect = 6.4
Identities = 59/297 (19%), Positives = 123/297 (41%), Gaps = 38/297 (12%)
Query: 3041 IAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKK 3100
+++ +++G KE ++L L +L ++ VL K+A+ + LE + + E +
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENEL 2597
Query: 3101 KLAE-EKAMEIEEQNKVIAMEKA------EAETTLAEVMPILEAAKL----ELQKL---D 3146
+L + +K +E+ NK+ A E E AE+ L K ELQ L
Sbjct: 2598 ELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEI 2657
Query: 3147 KSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGV------MSDPNFLRSLMEI 3200
KS +++ +++ +C+ K E K + + + + + +
Sbjct: 2658 KSSKDQLKELTLENSELKKSLDCM--HKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLL 2715
Query: 3201 DFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREK 3260
D + + +++ + L T+ EE + K + +LK + E+ +
Sbjct: 2716 DTNKQYEVEIQTYREKL----TSKEECLSSQKLEIDLLKSSK---------EELNNSLKA 2762
Query: 3261 VARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRL 3317
++ TK + + N+L +KE E K + I ++L+EE EI+++ L
Sbjct: 2763 TTQILEELKKTKMDNLKYVNQL---KKENERAQGKMKLLIKSCKQLEEEKEILQKEL 2816
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,457,524
Number of Sequences: 37866
Number of extensions: 6989818
Number of successful extensions: 25491
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 246
Number of HSP's that attempted gapping in prelim test: 21736
Number of HSP's gapped (non-prelim): 3083
length of query: 4471
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4348
effective length of database: 13,590,000
effective search space: 59089320000
effective search space used: 59089320000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.