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Search of human proteins with 19743875
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743875 fumarate hydratase precursor [Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743875 fumarate hydratase precursor [Homo sapiens] 1006 0.0
gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens] 46 9e-05
gi|183227688 adenylosuccinate lyase isoform b [Homo sapiens] 43 8e-04
gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo sapi... 34 0.28
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi... 34 0.28
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi... 34 0.28
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 32 1.8
gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens] 30 6.8
>gi|19743875 fumarate hydratase precursor [Homo sapiens]
Length = 510
Score = 1006 bits (2602), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGEL 60
MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGEL
Sbjct: 1 MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGEL 60
Query: 61 KVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAI 120
KVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAI
Sbjct: 61 KVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAI 120
Query: 121 MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDH 180
MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDH
Sbjct: 121 MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDH 180
Query: 181 VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAV 240
VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAV
Sbjct: 181 VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAV 240
Query: 241 PLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL 300
PLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL
Sbjct: 241 PLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL 300
Query: 301 TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE 360
TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE
Sbjct: 301 TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE 360
Query: 361 NEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA 420
NEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA
Sbjct: 361 NEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA 420
Query: 421 RLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS 480
RLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS
Sbjct: 421 RLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS 480
Query: 481 TLKETAIELGYLTAEQFDEWVKPKDMLGPK 510
TLKETAIELGYLTAEQFDEWVKPKDMLGPK
Sbjct: 481 TLKETAIELGYLTAEQFDEWVKPKDMLGPK 510
>gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens]
Length = 484
Score = 45.8 bits (107), Expect = 9e-05
Identities = 64/293 (21%), Positives = 115/293 (39%), Gaps = 22/293 (7%)
Query: 205 EVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKA 264
++LLP L ++ L +KE A + +G TH Q A T+G+ ++Q + + +K
Sbjct: 129 DLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKR 188
Query: 265 AMPRIYELAAGGTAVGT---------GLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEAL 315
+ GT GT G + ++ +K+ + A +T +
Sbjct: 189 VRDDLRFRGVKGT-TGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKV 247
Query: 316 AAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILP--ENEPGSSIMPGKVN 373
+E+ + + S+ KI DIR L + L E+ P + + GSS MP K N
Sbjct: 248 D-----IEVLSVLASLGASVHKICTDIRLL-----ANLKEMEEPFEKQQIGSSAMPYKRN 297
Query: 374 PTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTEN 433
P + E +A +M + S FE + + L A L D ++ +N
Sbjct: 298 PMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQN 357
Query: 434 CVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETA 486
G+ + I + + + L + N + KA + H+ L + A
Sbjct: 358 ISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQA 410
>gi|183227688 adenylosuccinate lyase isoform b [Homo sapiens]
Length = 425
Score = 42.7 bits (99), Expect = 8e-04
Identities = 59/267 (22%), Positives = 106/267 (39%), Gaps = 22/267 (8%)
Query: 205 EVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKA 264
++LLP L ++ L +KE A + +G TH Q A T+G+ ++Q + + +K
Sbjct: 129 DLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKR 188
Query: 265 AMPRIYELAAGGTAVGT---------GLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEAL 315
+ GT GT G + ++ +K+ + A +T +
Sbjct: 189 VRDDLRFRGVKGT-TGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKV 247
Query: 316 AAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILP--ENEPGSSIMPGKVN 373
+E+ + + S+ KI DIR L + L E+ P + + GSS MP K N
Sbjct: 248 D-----IEVLSVLASLGASVHKICTDIRLL-----ANLKEMEEPFEKQQIGSSAMPYKRN 297
Query: 374 PTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTEN 433
P + E +A +M + S FE + + L A L D ++ +N
Sbjct: 298 PMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQN 357
Query: 434 CVVGIQANTERINKLMNESLMLVTALN 460
G+ + I + + + L + N
Sbjct: 358 ISEGLVVYPKVIERRIRQELPFMATEN 384
>gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo
sapiens]
Length = 337
Score = 34.3 bits (77), Expect = 0.28
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 10/136 (7%)
Query: 263 KAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALV 322
K+ + + E+A G +G + F +++ ++ A AP A AA +
Sbjct: 134 KSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRA--------APPAPNAPAAGEDTT 185
Query: 323 ELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTM 382
E + A T A +D+R L R LG P+ P + GK ++ +
Sbjct: 186 ETAPAPGTPARGPRMTPSDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVG--DSSLL 243
Query: 383 VAAQVMGNHVAVTVGG 398
+ +V+ +HV V VGG
Sbjct: 244 IFVRVLRSHVMVRVGG 259
>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 34.3 bits (77), Expect = 0.28
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 10/136 (7%)
Query: 263 KAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALV 322
K+ + + E+A G +G + F +++ ++ A AP A AA +
Sbjct: 134 KSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRA--------APPAPNAPAAGEDTT 185
Query: 323 ELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTM 382
E + A T A +D+R L R LG P+ P + GK ++ +
Sbjct: 186 ETAPAPGTPARGPRMTPSDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVG--DSSLL 243
Query: 383 VAAQVMGNHVAVTVGG 398
+ +V+ +HV V VGG
Sbjct: 244 IFVRVLRSHVMVRVGG 259
>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
sapiens]
Length = 681
Score = 34.3 bits (77), Expect = 0.28
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 10/136 (7%)
Query: 263 KAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALV 322
K+ + + E+A G +G + F +++ ++ A AP A AA +
Sbjct: 134 KSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRA--------APPAPNAPAAGEDTT 185
Query: 323 ELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTM 382
E + A T A +D+R L R LG P+ P + GK ++ +
Sbjct: 186 ETAPAPGTPARGPRMTPSDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVG--DSSLL 243
Query: 383 VAAQVMGNHVAVTVGG 398
+ +V+ +HV V VGG
Sbjct: 244 IFVRVLRSHVMVRVGG 259
>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
member 2 [Homo sapiens]
Length = 812
Score = 31.6 bits (70), Expect = 1.8
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 228 IIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRI 287
I+ G + DAV + L F + Q + A + + + GG +G L
Sbjct: 237 ILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIA 296
Query: 288 GFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSL 335
F + + + L FV + + A + LSG M TAC++
Sbjct: 297 AFTTRFTHNIRVIEPL-FVFLYSYLSYITAE--MFHLSGIMAITACAM 341
>gi|55742678 glucocorticoid induced transcript 1 [Homo sapiens]
Length = 547
Score = 29.6 bits (65), Expect = 6.8
Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 11 SRPLVRAPAAALASAPGLGGAAVP---SFWPPNAARMASQ 47
+RP V A AA+L S PG G A P S PP AA A Q
Sbjct: 81 TRPPVAAAAASLGSLPGPGAARGPSPSSPTPPAAAAPAEQ 120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,548,127
Number of Sequences: 37866
Number of extensions: 709306
Number of successful extensions: 2016
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2013
Number of HSP's gapped (non-prelim): 8
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.