Search of human proteins with 194473657

Search of human proteins with 194473657

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194473657 deoxyribonuclease II beta isoform 1 precursor
[Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo...   756   0.0  
gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]        326   2e-89
gi|4503349 deoxyribonuclease II, lysosomal precursor [Homo sapiens]   236   3e-62
gi|5174421 copine 6 [Homo sapiens]                                     29   7.5  
gi|52630419 sterol regulatory element binding transcription fact...    28   9.8  
gi|22547195 sterol regulatory element binding transcription fact...    28   9.8  
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo...    28   9.8  
gi|147904340 WD repeat domain 82 [Homo sapiens]                        28   9.8  

>gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo
           sapiens]
          Length = 361

 Score =  756 bits (1953), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNKESGETG 60
           MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNKESGETG
Sbjct: 1   MKQKMMARLLRTSFALLFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPKRQNKESGETG 60

Query: 61  LEYLYLDSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNY 120
           LEYLYLDSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNY
Sbjct: 61  LEYLYLDSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKPVNY 120

Query: 121 SRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYE 180
           SRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYE
Sbjct: 121 SRKYGHTKGLLLWNRVQGFWLIHSIPQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYE 180

Query: 181 AIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHF 240
           AIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHF
Sbjct: 181 AIDSQLLVCNPNVYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHF 240

Query: 241 AKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFS 300
           AKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFS
Sbjct: 241 AKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFS 300

Query: 301 SYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC 360
           SYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC
Sbjct: 301 SYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC 360

Query: 361 K 361
           K
Sbjct: 361 K 361


>gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]
          Length = 153

 Score =  326 bits (835), Expect = 2e-89
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 209 MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW 268
           MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW
Sbjct: 1   MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETW 60

Query: 269 QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS 328
           QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS
Sbjct: 61  QRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRS 120

Query: 329 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK 361
           PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
Sbjct: 121 PHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK 153


>gi|4503349 deoxyribonuclease II, lysosomal precursor [Homo sapiens]
          Length = 360

 Score =  236 bits (601), Expect = 3e-62
 Identities = 129/350 (36%), Positives = 190/350 (54%), Gaps = 12/350 (3%)

Query: 17  LFLGLFGVLGAATISCRNEEGKAVDWFTFYKLPK-RQNKESGETGLEYLYLDSTTRSWRK 75
           L L     + A  ++C  + G+ VDWF  YKLP  R + E+ + GL+Y YLD ++  WR 
Sbjct: 4   LLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRD 63

Query: 76  SEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYNDGVPKP--VNYSRKYGHTKGLLLW 133
              L+N  +  +GR+LQ LY    S ++  A+L+YND  P+P     S   GHTKG+LL 
Sbjct: 64  GRALINSPEGAVGRSLQPLYR---SNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLL 120

Query: 134 NRVQGFWLIHSIPQFPP-IPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPN 192
           +   GFWL+HS+P FPP      Y +P +    GQ+ +C++F + Q+  +  QL    P 
Sbjct: 121 DHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPW 180

Query: 193 VYSCSIPATFHQELIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFA 252
           VY+  +   F QE   +  +      S+ P     TL S  G  F  FAK   F DD+++
Sbjct: 181 VYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYS 240

Query: 253 AWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHS--YFSSYQDHAKWCI 310
            W+A  L T+L  + W +    LPSNCS  + V N+  I     +   F+S +DH+KWC+
Sbjct: 241 GWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCV 300

Query: 311 SQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESC 360
           S KG    WTC+GD+NR+  +  R GG +C Q   +++AFQ LV  Y+ C
Sbjct: 301 SPKGP---WTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPC 347


>gi|5174421 copine 6 [Homo sapiens]
          Length = 557

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 24/119 (20%)

Query: 240 FAKSDSFLDDIFA--------AWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAI 291
           F+KSD F++             W  + +K +L   +W+  R  L S CS   H    + +
Sbjct: 169 FSKSDPFMEIYKTNEDQSDQLVWRTEVVKNNL-NPSWEPFRLSLHSLCSCDVH----RPL 223

Query: 292 KLSRHSYFSSYQDH------AKWCISQKGTKN-----RWTCIGDLNRSPHQAFRSGGFI 339
           K   + Y SS +        + +   Q+GT N     +W CI    R   + ++S G +
Sbjct: 224 KFLVYDYDSSGKHDFIGEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKNYKSSGTV 282


>gi|52630419 sterol regulatory element binding transcription factor
           1 isoform a [Homo sapiens]
          Length = 1177

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 9/104 (8%)

Query: 146 PQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQE 205
           PQF   P  GY  PP G   G          N  + +    L   P V   S+  T  Q 
Sbjct: 185 PQFSSTPVLGYPSPPGGFSTGSP------PGNTQQPLPGLPLASPPGVPPVSL-HTQVQS 237

Query: 206 LIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFL--HFAKSDSFL 247
           ++    L   A+ +  P     T Q  Q    L  HF K+DS L
Sbjct: 238 VVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLL 281


>gi|22547195 sterol regulatory element binding transcription factor
           1 isoform b [Homo sapiens]
          Length = 1147

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 9/104 (8%)

Query: 146 PQFPPIPEEGYDYPPTGRRNGQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQE 205
           PQF   P  GY  PP G   G          N  + +    L   P V   S+  T  Q 
Sbjct: 155 PQFSSTPVLGYPSPPGGFSTGSP------PGNTQQPLPGLPLASPPGVPPVSL-HTQVQS 207

Query: 206 LIHMPQLCTRASSSEIPGRLLTTLQSAQGQKFL--HFAKSDSFL 247
           ++    L   A+ +  P     T Q  Q    L  HF K+DS L
Sbjct: 208 VVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLL 251


>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
           sapiens]
          Length = 859

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 14/77 (18%)

Query: 146 PQFPPIPEEGYDYPPTGRRN-GQSGICITFKYNQYEAIDSQLLVCNPNVYSCSIPATFHQ 204
           P  PP P +GY + P  R + G SG  I  + N +E    ++ +             +H 
Sbjct: 11  PPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDI-------------YHY 57

Query: 205 ELIHMPQLCTRASSSEI 221
           EL   P+ C R  + EI
Sbjct: 58  ELDIKPEKCPRRVNREI 74


>gi|147904340 WD repeat domain 82 [Homo sapiens]
          Length = 313

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 67  DSTTRSWRKSEQLMNDTKSVLGRTLQQLYEAYASKSNNTAYLIYN--DGVPKPVNYSRKY 124
           DS  RS+R ++    ++  +         E   S S++ + ++Y+  +G PK   YS+KY
Sbjct: 5   DSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKY 64

Query: 125 G 125
           G
Sbjct: 65  G 65


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,865,012
Number of Sequences: 37866
Number of extensions: 699585
Number of successful extensions: 1376
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1367
Number of HSP's gapped (non-prelim): 8
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.