Guide to the Human Genome
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Search of human proteins with 194394146

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]
         (892 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]                    1851   0.0  
gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]          1108   0.0  
gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]          1108   0.0  
gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]          1010   0.0  
gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]           779   0.0  
gi|18765694 dipeptidylpeptidase IV [Homo sapiens]                     153   8e-37
gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]      143   6e-34
gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]       143   6e-34
gi|86792863 dipeptidyl-peptidase 6 isoform 3 [Homo sapiens]           140   4e-33
gi|86792778 dipeptidyl-peptidase 6 isoform 2 [Homo sapiens]           140   4e-33
gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens]           140   4e-33
gi|16933540 fibroblast activation protein, alpha subunit [Homo s...   137   3e-32
gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]           72   2e-12
gi|41349456 prolyl endopeptidase [Homo sapiens]                        37   0.063
gi|40538788 neuroligin 4, Y-linked [Homo sapiens]                      36   0.18 
gi|30840978 neuroligin 2 [Homo sapiens]                                35   0.24 
gi|33563374 carboxylesterase 3 [Homo sapiens]                          33   0.90 
gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo sa...    33   1.2  
gi|122939159 peptidyl arginine deiminase, type II [Homo sapiens]       32   2.0  
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]                32   2.6  
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]                32   2.6  
gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]        32   3.4  
gi|81295416 sushi domain containing 4 isoform b [Homo sapiens]         32   3.4  
gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]            31   5.9  
gi|46094081 development and differentiation enhancing factor 1 [...    30   10.0 

>gi|194394146 dipeptidylpeptidase 9 [Homo sapiens]
          Length = 892

 Score = 1851 bits (4794), Expect = 0.0
 Identities = 892/892 (100%), Positives = 892/892 (100%)

Query: 1   MRKVKKLRLDKENTGSWRSFSLNSEGAERMATTGTPTADRGDAAATDDPAARFQVQKHSW 60
           MRKVKKLRLDKENTGSWRSFSLNSEGAERMATTGTPTADRGDAAATDDPAARFQVQKHSW
Sbjct: 1   MRKVKKLRLDKENTGSWRSFSLNSEGAERMATTGTPTADRGDAAATDDPAARFQVQKHSW 60

Query: 61  DGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEI 120
           DGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEI
Sbjct: 61  DGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEI 120

Query: 121 PKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLF 180
           PKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLF
Sbjct: 121 PKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLF 180

Query: 181 LFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWV 240
           LFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWV
Sbjct: 181 LFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWV 240

Query: 241 ANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLK 300
           ANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLK
Sbjct: 241 ANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLK 300

Query: 301 TLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIV 360
           TLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIV
Sbjct: 301 TLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIV 360

Query: 361 STQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTE 420
           STQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTE
Sbjct: 361 STQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTE 420

Query: 421 NEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGF 480
           NEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGF
Sbjct: 421 NEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGF 480

Query: 481 CHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETK 540
           CHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETK
Sbjct: 481 CHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETK 540

Query: 541 LVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPC 600
           LVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPC
Sbjct: 541 LVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPC 600

Query: 601 VHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAL 660
           VHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAL
Sbjct: 601 VHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAL 660

Query: 661 QPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEG 720
           QPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEG
Sbjct: 661 QPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEG 720

Query: 721 ALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAI 780
           ALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAI
Sbjct: 721 ALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAI 780

Query: 781 AGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENV 840
           AGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENV
Sbjct: 781 AGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENV 840

Query: 841 HFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           HFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL
Sbjct: 841 HFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892


>gi|37577089 dipeptidyl peptidase 8 isoform 3 [Homo sapiens]
          Length = 898

 Score = 1108 bits (2867), Expect = 0.0
 Identities = 517/840 (61%), Positives = 651/840 (77%), Gaps = 2/840 (0%)

Query: 53  FQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRE 112
           F V+++SW  L+ ++  +RKY G ++ KAPHDF FV++ D  GPHS R+YYL M   +RE
Sbjct: 51  FYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRE 110

Query: 113 NSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYD 172
           N+L YSEIPK + + A+L+LSWK +LD FQAT  +G+YSREEELLRERKR+G  GI SYD
Sbjct: 111 NTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYD 170

Query: 173 FHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSF 232
           +H  SG FLFQA + ++H +DGG  GF   P++P  ++T C   RMDPK+CPADP + +F
Sbjct: 171 YHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAF 230

Query: 233 INNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTAS 292
           I+++D+W++NI T EERRLT+ H  L+N+ +D +SAGVATFV+QEEFDR++GYWWCP A 
Sbjct: 231 IHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAE 290

Query: 293 WEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQ 352
              S G K LRILYEE DESEVE+IHV SP LE R+ DS+RYP+TG+ NPK+  K++E  
Sbjct: 291 TTPSGG-KILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIM 349

Query: 353 TDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPP 412
            D++G+I+   +KEL+QPF  LF  VEYIARAGWT +GKYAW++ LDR Q  LQ+VL+ P
Sbjct: 350 IDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISP 409

Query: 413 ALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLR 472
            LFIP  ++  +R     +VP +V P ++YEE T++WIN+HDIF+ FPQS  E+E+ F+ 
Sbjct: 410 ELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSH-EEEIEFIF 468

Query: 473 ANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSK 532
           A+ECKTGF HLYK+T++LK   Y  S    P   +FKCPIKEEIA+TSGEWEVL RHGS 
Sbjct: 469 ASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSN 528

Query: 533 IWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHY 592
           I V+E  +LVYF+GTKD+PLEHHLYVVSY   GE+ RLT  G+SHSC +SQ+ D F+S Y
Sbjct: 529 IQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKY 588

Query: 593 SSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYG 652
           S+   P CV +YKLS P+DDP  K   FWA+++++A   PDY PPEIF F + +   LYG
Sbjct: 589 SNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYG 648

Query: 653 MIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSC 712
           M+YKPH LQPGKK+PTVLF+YGGPQVQLVNN FKG+KY RLNTLASLGY VVVID RGSC
Sbjct: 649 MLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSC 708

Query: 713 QRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHK 772
            RGL+FEGA K +MGQ+EI+DQVEGLQ++A +Y FIDL RV IHGWSYGG+LSLM L+ +
Sbjct: 709 HRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQR 768

Query: 773 PQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLIL 832
             +F+VAIAGAPVT+W+ YDTGYTERYM  P+ N+ GY  GSVA+  EK P+EPNRLL+L
Sbjct: 769 SDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLL 828

Query: 833 HGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           HGFLDENVHF HT+ L+S L+RAGKPY LQIYP ERHSIR PESGEHYE+ LLH+LQE L
Sbjct: 829 HGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENL 888


>gi|18450280 dipeptidyl peptidase 8 isoform 1 [Homo sapiens]
          Length = 882

 Score = 1108 bits (2867), Expect = 0.0
 Identities = 517/840 (61%), Positives = 651/840 (77%), Gaps = 2/840 (0%)

Query: 53  FQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRE 112
           F V+++SW  L+ ++  +RKY G ++ KAPHDF FV++ D  GPHS R+YYL M   +RE
Sbjct: 35  FYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRE 94

Query: 113 NSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYD 172
           N+L YSEIPK + + A+L+LSWK +LD FQAT  +G+YSREEELLRERKR+G  GI SYD
Sbjct: 95  NTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYD 154

Query: 173 FHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSF 232
           +H  SG FLFQA + ++H +DGG  GF   P++P  ++T C   RMDPK+CPADP + +F
Sbjct: 155 YHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAF 214

Query: 233 INNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTAS 292
           I+++D+W++NI T EERRLT+ H  L+N+ +D +SAGVATFV+QEEFDR++GYWWCP A 
Sbjct: 215 IHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAE 274

Query: 293 WEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQ 352
              S G K LRILYEE DESEVE+IHV SP LE R+ DS+RYP+TG+ NPK+  K++E  
Sbjct: 275 TTPSGG-KILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIM 333

Query: 353 TDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPP 412
            D++G+I+   +KEL+QPF  LF  VEYIARAGWT +GKYAW++ LDR Q  LQ+VL+ P
Sbjct: 334 IDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISP 393

Query: 413 ALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLR 472
            LFIP  ++  +R     +VP +V P ++YEE T++WIN+HDIF+ FPQS  E+E+ F+ 
Sbjct: 394 ELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSH-EEEIEFIF 452

Query: 473 ANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSK 532
           A+ECKTGF HLYK+T++LK   Y  S    P   +FKCPIKEEIA+TSGEWEVL RHGS 
Sbjct: 453 ASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSN 512

Query: 533 IWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHY 592
           I V+E  +LVYF+GTKD+PLEHHLYVVSY   GE+ RLT  G+SHSC +SQ+ D F+S Y
Sbjct: 513 IQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKY 572

Query: 593 SSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYG 652
           S+   P CV +YKLS P+DDP  K   FWA+++++A   PDY PPEIF F + +   LYG
Sbjct: 573 SNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYG 632

Query: 653 MIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSC 712
           M+YKPH LQPGKK+PTVLF+YGGPQVQLVNN FKG+KY RLNTLASLGY VVVID RGSC
Sbjct: 633 MLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSC 692

Query: 713 QRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHK 772
            RGL+FEGA K +MGQ+EI+DQVEGLQ++A +Y FIDL RV IHGWSYGG+LSLM L+ +
Sbjct: 693 HRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQR 752

Query: 773 PQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLIL 832
             +F+VAIAGAPVT+W+ YDTGYTERYM  P+ N+ GY  GSVA+  EK P+EPNRLL+L
Sbjct: 753 SDIFRVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLL 812

Query: 833 HGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           HGFLDENVHF HT+ L+S L+RAGKPY LQIYP ERHSIR PESGEHYE+ LLH+LQE L
Sbjct: 813 HGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENL 872


>gi|37577091 dipeptidyl peptidase 8 isoform 4 [Homo sapiens]
          Length = 847

 Score = 1010 bits (2611), Expect = 0.0
 Identities = 484/840 (57%), Positives = 608/840 (72%), Gaps = 53/840 (6%)

Query: 53  FQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRE 112
           F V+++SW  L+ ++  +RKY G ++ KAPHDF FV++ D  GPHS R+YYL M   +RE
Sbjct: 51  FYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRE 110

Query: 113 NSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYD 172
           N+L YSEIPK + + A+L+LSWK +LD FQAT  +G+YSREEELLRERKR+G  GI SYD
Sbjct: 111 NTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYD 170

Query: 173 FHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSF 232
           +H  SG FLFQA + ++H +DGG  GF   P++P  ++T C   RMDPK+CPADP + +F
Sbjct: 171 YHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAF 230

Query: 233 INNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTAS 292
           I+++D+W++NI T EERRLT+ H  L+N+ +D +SAGVATFV+QEEFDR++GYWWCP A 
Sbjct: 231 IHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAE 290

Query: 293 WEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQ 352
              S G K LRILYEE DESEVE+IHV SP LE R+ DS+RYP+TG+ NPK+  K++E  
Sbjct: 291 TTPSGG-KILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIM 349

Query: 353 TDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPP 412
            D++G+I+   +KEL+QPF  LF  VEYIARAGWT +GKYAW++ LDR Q  LQ+VL+ P
Sbjct: 350 IDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISP 409

Query: 413 ALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLR 472
            LFIP  ++  +R     +VP +V P ++YEE T++WIN+HDIF+ FPQS  E+E+ F+ 
Sbjct: 410 ELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSH-EEEIEFIF 468

Query: 473 ANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSK 532
           A+ECKTGF HLYK+T++LK   Y  S    P   +FKCPIKEEIA+TSGEWEVL RHGS 
Sbjct: 469 ASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSN 528

Query: 533 IWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHY 592
           I V+E  +LVYF+GTKD+PLEHHLYVVSY   GE+ RLT  G+SHSC +SQ+ D F+S Y
Sbjct: 529 IQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKY 588

Query: 593 SSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYG 652
           S+   P CV +YKLS P+DDP  K   FWA+++++A   PDY PPEIF F + +   LYG
Sbjct: 589 SNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYG 648

Query: 653 MIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSC 712
           M+YKPH LQPGKK+PTVLF+YGGPQVQLVNN FKG+KY RLNTLASLGY VVVID RGSC
Sbjct: 649 MLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSC 708

Query: 713 QRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHK 772
            RGL+FEGA K +M                                              
Sbjct: 709 HRGLKFEGAFKYKM---------------------------------------------- 722

Query: 773 PQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLIL 832
                VAIAGAPVT+W+ YDTGYTERYM  P+ N+ GY  GSVA+  EK P+EPNRLL+L
Sbjct: 723 -----VAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLL 777

Query: 833 HGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           HGFLDENVHF HT+ L+S L+RAGKPY LQIYP ERHSIR PESGEHYE+ LLH+LQE L
Sbjct: 778 HGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENL 837


>gi|18450278 dipeptidyl peptidase 8 isoform 2 [Homo sapiens]
          Length = 782

 Score =  779 bits (2011), Expect = 0.0
 Identities = 361/628 (57%), Positives = 471/628 (75%), Gaps = 2/628 (0%)

Query: 53  FQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRE 112
           F V+++SW  L+ ++  +RKY G ++ KAPHDF FV++ D  GPHS R+YYL M   +RE
Sbjct: 35  FYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRE 94

Query: 113 NSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYD 172
           N+L YSEIPK + + A+L+LSWK +LD FQAT  +G+YSREEELLRERKR+G  GI SYD
Sbjct: 95  NTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYD 154

Query: 173 FHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSF 232
           +H  SG FLFQA + ++H +DGG  GF   P++P  ++T C   RMDPK+CPADP + +F
Sbjct: 155 YHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAF 214

Query: 233 INNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTAS 292
           I+++D+W++NI T EERRLT+ H  L+N+ +D +SAGVATFV+QEEFDR++GYWWCP A 
Sbjct: 215 IHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAE 274

Query: 293 WEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQ 352
              S G K LRILYEE DESEVE+IHV SP LE R+ DS+RYP+TG+ NPK+  K++E  
Sbjct: 275 TTPSGG-KILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIM 333

Query: 353 TDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPP 412
            D++G+I+   +KEL+QPF  LF  VEYIARAGWT +GKYAW++ LDR Q  LQ+VL+ P
Sbjct: 334 IDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISP 393

Query: 413 ALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLR 472
            LFIP  ++  +R     +VP +V P ++YEE T++WIN+HDIF+ FPQS  E+E+ F+ 
Sbjct: 394 ELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSH-EEEIEFIF 452

Query: 473 ANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSK 532
           A+ECKTGF HLYK+T++LK   Y  S    P   +FKCPIKEEIA+TSGEWEVL RHGS 
Sbjct: 453 ASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSN 512

Query: 533 IWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHY 592
           I V+E  +LVYF+GTKD+PLEHHLYVVSY   GE+ RLT  G+SHSC +SQ+ D F+S Y
Sbjct: 513 IQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKY 572

Query: 593 SSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYG 652
           S+   P CV +YKLS P+DDP  K   FWA+++++A   PDY PPEIF F + +   LYG
Sbjct: 573 SNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYG 632

Query: 653 MIYKPHALQPGKKHPTVLFVYGGPQVQL 680
           M+YKPH LQPGKK+PTVLF+YGGPQV +
Sbjct: 633 MLYKPHDLQPGKKYPTVLFIYGGPQVAI 660



 Score =  184 bits (466), Expect = 4e-46
 Identities = 85/116 (73%), Positives = 98/116 (84%)

Query: 777 KVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFL 836
           +VAIAGAPVT+W+ YDTGYTERYM  P+ N+ GY  GSVA+  EK P+EPNRLL+LHGFL
Sbjct: 657 QVAIAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFL 716

Query: 837 DENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           DENVHF HT+ L+S L+RAGKPY LQIYP ERHSIR PESGEHYE+ LLH+LQE L
Sbjct: 717 DENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENL 772


>gi|18765694 dipeptidylpeptidase IV [Homo sapiens]
          Length = 766

 Score =  153 bits (386), Expect = 8e-37
 Identities = 169/677 (24%), Positives = 273/677 (40%), Gaps = 97/677 (14%)

Query: 231 SFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEE-FDRFTGYWWCP 289
           +++ N+D++V         R+T+  +      +D    G+  +V +EE F  ++  WW P
Sbjct: 165 AYVWNNDIYVKIEPNLPSYRITWTGK------EDIIYNGITDWVYEEEVFSAYSALWWSP 218

Query: 290 TASWEGSEGLKTLRILYEEVDESEVEVIHVP---SPALEERKTDSYRYPRTGSKNPKIAL 346
             ++          + Y + +++EV +I        +L+  KT    YP+ G+ NP +  
Sbjct: 219 NGTF----------LAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTV-- 266

Query: 347 KLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQ 406
           K     TDS   + +    ++  P S L     Y+    W    + +         QWL+
Sbjct: 267 KFFVVNTDSLSSVTNATSIQITAPASMLIGD-HYLCDVTWATQERISL--------QWLR 317

Query: 407 LVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGED 466
            +     + I   +    R     A           E  T  W+     F P       D
Sbjct: 318 RIQNYSVMDICDYDESSGRWNCLVARQH-------IEMSTTGWVGR---FRPSEPHFTLD 367

Query: 467 ELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVL 526
              F +    + G+ H+                        F+   K+   +T G WEV+
Sbjct: 368 GNSFYKIISNEEGYRHICY----------------------FQIDKKDCTFITKGTWEVI 405

Query: 527 ARHGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSM-SQN 584
                 I       L Y     K  P   +LY +      ++  L+       C   S +
Sbjct: 406 G-----IEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVS 460

Query: 585 FDMFVSHYSSVSTPPCVHVYKLSGPDDDP---LHKQPRFWASMMEAASCPPDYVPPEIFH 641
           F     +Y    + P + +Y L    +D    + +       M++        +P +   
Sbjct: 461 FSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQ-----MPSKKLD 515

Query: 642 FHTRSDVRL-YGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLN---TLA 697
           F   ++ +  Y MI  PH     KK+P +L VY GP  Q  +  F      RLN    LA
Sbjct: 516 FIILNETKFWYQMILPPH-FDKSKKYPLLLDVYAGPCSQKADTVF------RLNWATYLA 568

Query: 698 SLGYAVVV-IDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGL-QFVAEKYGFIDLSRVAI 755
           S    +V   DGRGS  +G +   A+  ++G  E+EDQ+E   QF   K GF+D  R+AI
Sbjct: 569 STENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF--SKMGFVDNKRIAI 626

Query: 756 HGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDV--PENNQHGYEAG 813
            GWSYGG+++ M L     VFK  IA APV+ W  YD+ YTERYM +  PE+N   Y   
Sbjct: 627 WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNS 686

Query: 814 SVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRC 873
           +V    E    +    L++HG  D+NVHF  +  +   L+  G  +Q   Y +E H I  
Sbjct: 687 TVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744

Query: 874 PESGEHYEVTLLHFLQE 890
             + +H    + HF+++
Sbjct: 745 STAHQHIYTHMSHFIKQ 761


>gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]
          Length = 789

 Score =  143 bits (361), Expect = 6e-34
 Identities = 159/629 (25%), Positives = 257/629 (40%), Gaps = 77/629 (12%)

Query: 269 GVATFVIQEEF-DRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVP--SPALE 325
           G+A ++ +EE       +WW P             R+ +  +++S V  + +P  + AL 
Sbjct: 218 GIADWLYEEELLHSHIAHWWSPDGE----------RLAFLMINDSLVPTMVIPRFTGALY 267

Query: 326 ERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAG 385
             K   Y YP+ G  NP I L +             T   EL+ P  S   +  YI    
Sbjct: 268 P-KGKQYPYPKAGQVNPTIKLYVVNLYGP-------THTLELMPP-DSFKSREYYITMVK 318

Query: 386 WTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEV 445
           W  + K     +L+R Q    L +        S +                     YE  
Sbjct: 319 WVSNTKTV-VRWLNRAQNISILTVCETTTGACSKK---------------------YEMT 356

Query: 446 TNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGE 505
           ++ W+           S+  +E  F R           + +T  +K  G       +   
Sbjct: 357 SDTWL-----------SQQNEEPVFSRDGS-------KFFMTVPVKQGGRGEFHHIAMFL 398

Query: 506 DEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAG 565
            + K        LTSG WEV+      +  +E T+ +YF  T+ +P    LY  S E   
Sbjct: 399 IQSKSEQITVRHLTSGNWEVI----KILAYDETTQKIYFLSTESSPRGRQLYSASTEGLL 454

Query: 566 EIVRLTTPGFSHSCS-MSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASM 624
               ++       C+    +F     H+      P V V  L   D+ P         SM
Sbjct: 455 NRQCISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDN-PAKYFILESNSM 513

Query: 625 MEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNS 684
           ++ A        PEI   H   D  L   +  P       ++  +L +   P  QLV + 
Sbjct: 514 LKEAILKKKIGKPEIKILHI-DDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDK 572

Query: 685 FKGIKYLRLNTLASLGYAVVV-IDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAE 743
           F  I +   + L  +   +V   DGRGS  +GL+    +  ++G VE++DQ+  ++F+  
Sbjct: 573 FH-IDWD--SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLL- 628

Query: 744 KYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVP 803
           K  +ID  R++I G  YGG+++ M L    ++FK     AP+T    Y + ++ERY+ +P
Sbjct: 629 KLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMP 688

Query: 804 ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQI 863
              +  Y+A SV  +V  L  E   +LI+HG  D  VHF H+  L+  LI+AG  Y +Q+
Sbjct: 689 SKEESTYQAASVLHNVHGLKEE--NILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQV 746

Query: 864 YPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           YP+E H++   +S  H   T+L F  + L
Sbjct: 747 YPDEGHNV-SEKSKYHLYSTILKFFSDCL 774


>gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]
          Length = 796

 Score =  143 bits (361), Expect = 6e-34
 Identities = 159/629 (25%), Positives = 257/629 (40%), Gaps = 77/629 (12%)

Query: 269 GVATFVIQEEF-DRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVP--SPALE 325
           G+A ++ +EE       +WW P             R+ +  +++S V  + +P  + AL 
Sbjct: 225 GIADWLYEEELLHSHIAHWWSPDGE----------RLAFLMINDSLVPTMVIPRFTGALY 274

Query: 326 ERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAG 385
             K   Y YP+ G  NP I L +             T   EL+ P  S   +  YI    
Sbjct: 275 P-KGKQYPYPKAGQVNPTIKLYVVNLYGP-------THTLELMPP-DSFKSREYYITMVK 325

Query: 386 WTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEV 445
           W  + K     +L+R Q    L +        S +                     YE  
Sbjct: 326 WVSNTKTV-VRWLNRAQNISILTVCETTTGACSKK---------------------YEMT 363

Query: 446 TNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGE 505
           ++ W+           S+  +E  F R           + +T  +K  G       +   
Sbjct: 364 SDTWL-----------SQQNEEPVFSRDGS-------KFFMTVPVKQGGRGEFHHIAMFL 405

Query: 506 DEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAG 565
            + K        LTSG WEV+      +  +E T+ +YF  T+ +P    LY  S E   
Sbjct: 406 IQSKSEQITVRHLTSGNWEVI----KILAYDETTQKIYFLSTESSPRGRQLYSASTEGLL 461

Query: 566 EIVRLTTPGFSHSCS-MSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASM 624
               ++       C+    +F     H+      P V V  L   D+ P         SM
Sbjct: 462 NRQCISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDN-PAKYFILESNSM 520

Query: 625 MEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNS 684
           ++ A        PEI   H   D  L   +  P       ++  +L +   P  QLV + 
Sbjct: 521 LKEAILKKKIGKPEIKILHI-DDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDK 579

Query: 685 FKGIKYLRLNTLASLGYAVVV-IDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAE 743
           F  I +   + L  +   +V   DGRGS  +GL+    +  ++G VE++DQ+  ++F+  
Sbjct: 580 FH-IDWD--SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLL- 635

Query: 744 KYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVP 803
           K  +ID  R++I G  YGG+++ M L    ++FK     AP+T    Y + ++ERY+ +P
Sbjct: 636 KLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMP 695

Query: 804 ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQI 863
              +  Y+A SV  +V  L  E   +LI+HG  D  VHF H+  L+  LI+AG  Y +Q+
Sbjct: 696 SKEESTYQAASVLHNVHGLKEE--NILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQV 753

Query: 864 YPNERHSIRCPESGEHYEVTLLHFLQEYL 892
           YP+E H++   +S  H   T+L F  + L
Sbjct: 754 YPDEGHNV-SEKSKYHLYSTILKFFSDCL 781


>gi|86792863 dipeptidyl-peptidase 6 isoform 3 [Homo sapiens]
          Length = 801

 Score =  140 bits (354), Expect = 4e-33
 Identities = 162/640 (25%), Positives = 270/640 (42%), Gaps = 99/640 (15%)

Query: 269 GVATFVIQEEFDR-FTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEER 327
           G++ ++ +EE  +    +WW P  +          R+ Y  +++S V ++ +P+      
Sbjct: 223 GLSDWLYEEEILKTHIAHWWSPDGT----------RLAYAAINDSRVPIMELPTYTGSIY 272

Query: 328 KT-DSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGW 386
            T   Y YP+ GS+NP I+L +        G    T + E++ P      +  YI    W
Sbjct: 273 PTVKPYHYPKAGSENPSISLHVI-------GLNGPTHDLEMMPPDDPRMREY-YITMVKW 324

Query: 387 TRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVT 446
               K A   +L+R Q    L L      + + ++E++                     +
Sbjct: 325 ATSTKVA-VTWLNRAQNVSILTLCDATTGVCTKKHEDE---------------------S 362

Query: 447 NVWI---NVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSP 503
             W+   N   +F     S+   +  F+RA   + G    Y +T          S+P S 
Sbjct: 363 EAWLHRQNEEPVF-----SKDGRKFFFIRAIP-QGGRGKFYHITV-------SSSQPNSS 409

Query: 504 GEDEFKCPIKEEIALTSGEWEVLARHGSKIWV-NEETKLVYFQGTKDTPLEHHLYVVSYE 562
            ++          ++TSG+W+V     +KI   +E+   +YF  T+D P    LY  S  
Sbjct: 410 NDNIQ--------SITSGDWDV-----TKILAYDEKGNKIYFLSTEDLPRRRQLY--SAN 454

Query: 563 AAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPD------DDPLHK 616
             G   R        SC + +N   F + +S         + K  GP        +   K
Sbjct: 455 TVGNFNRQCL-----SCDLVENCTYFSASFSHSMD---FFLLKCEGPGVPMVTVHNTTDK 506

Query: 617 QPRFWASMME-AASCPPDYVPPEIFHFHTR-SDVRLYGMIYKPHALQPGKKHPTVLFVYG 674
           +  F     E       D   P++ +      D  L   I KP        +P +L V G
Sbjct: 507 KKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDG 566

Query: 675 GPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQ 734
            P  Q V   F+ + +  +  ++S G  VV  DGRGS  +G +    ++ ++G +E +DQ
Sbjct: 567 TPGSQSVAEKFE-VSWETV-MVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQ 624

Query: 735 VEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKP----QVFKVAIAGAPVTVWMA 790
           +E ++ + ++  +ID +RVA+ G  YGG+LS   L  K     Q F    A +P+T +  
Sbjct: 625 MEAVRTMLKEQ-YIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKL 683

Query: 791 YDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVS 850
           Y + ++ERY+ +   +   YE   VA  V  L  E  + LI+H   DE +HF HT  L++
Sbjct: 684 YASAFSERYLGLHGLDNRAYEMTKVAHRVSAL--EEQQFLIIHPTADEKIHFQHTAELIT 741

Query: 851 QLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQE 890
           QLIR    Y LQIYP+E H        +H   ++++F  E
Sbjct: 742 QLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINFFVE 781


>gi|86792778 dipeptidyl-peptidase 6 isoform 2 [Homo sapiens]
          Length = 803

 Score =  140 bits (354), Expect = 4e-33
 Identities = 162/640 (25%), Positives = 270/640 (42%), Gaps = 99/640 (15%)

Query: 269 GVATFVIQEEFDR-FTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEER 327
           G++ ++ +EE  +    +WW P  +          R+ Y  +++S V ++ +P+      
Sbjct: 225 GLSDWLYEEEILKTHIAHWWSPDGT----------RLAYAAINDSRVPIMELPTYTGSIY 274

Query: 328 KT-DSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGW 386
            T   Y YP+ GS+NP I+L +        G    T + E++ P      +  YI    W
Sbjct: 275 PTVKPYHYPKAGSENPSISLHVI-------GLNGPTHDLEMMPPDDPRMREY-YITMVKW 326

Query: 387 TRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVT 446
               K A   +L+R Q    L L      + + ++E++                     +
Sbjct: 327 ATSTKVA-VTWLNRAQNVSILTLCDATTGVCTKKHEDE---------------------S 364

Query: 447 NVWI---NVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSP 503
             W+   N   +F     S+   +  F+RA   + G    Y +T          S+P S 
Sbjct: 365 EAWLHRQNEEPVF-----SKDGRKFFFIRAIP-QGGRGKFYHITV-------SSSQPNSS 411

Query: 504 GEDEFKCPIKEEIALTSGEWEVLARHGSKIWV-NEETKLVYFQGTKDTPLEHHLYVVSYE 562
            ++          ++TSG+W+V     +KI   +E+   +YF  T+D P    LY  S  
Sbjct: 412 NDNIQ--------SITSGDWDV-----TKILAYDEKGNKIYFLSTEDLPRRRQLY--SAN 456

Query: 563 AAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPD------DDPLHK 616
             G   R        SC + +N   F + +S         + K  GP        +   K
Sbjct: 457 TVGNFNRQCL-----SCDLVENCTYFSASFSHSMD---FFLLKCEGPGVPMVTVHNTTDK 508

Query: 617 QPRFWASMME-AASCPPDYVPPEIFHFHTR-SDVRLYGMIYKPHALQPGKKHPTVLFVYG 674
           +  F     E       D   P++ +      D  L   I KP        +P +L V G
Sbjct: 509 KKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDG 568

Query: 675 GPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQ 734
            P  Q V   F+ + +  +  ++S G  VV  DGRGS  +G +    ++ ++G +E +DQ
Sbjct: 569 TPGSQSVAEKFE-VSWETV-MVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQ 626

Query: 735 VEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKP----QVFKVAIAGAPVTVWMA 790
           +E ++ + ++  +ID +RVA+ G  YGG+LS   L  K     Q F    A +P+T +  
Sbjct: 627 MEAVRTMLKEQ-YIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKL 685

Query: 791 YDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVS 850
           Y + ++ERY+ +   +   YE   VA  V  L  E  + LI+H   DE +HF HT  L++
Sbjct: 686 YASAFSERYLGLHGLDNRAYEMTKVAHRVSAL--EEQQFLIIHPTADEKIHFQHTAELIT 743

Query: 851 QLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQE 890
           QLIR    Y LQIYP+E H        +H   ++++F  E
Sbjct: 744 QLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINFFVE 783


>gi|86792774 dipeptidyl-peptidase 6 isoform 1 [Homo sapiens]
          Length = 865

 Score =  140 bits (354), Expect = 4e-33
 Identities = 162/640 (25%), Positives = 270/640 (42%), Gaps = 99/640 (15%)

Query: 269 GVATFVIQEEFDR-FTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEER 327
           G++ ++ +EE  +    +WW P  +          R+ Y  +++S V ++ +P+      
Sbjct: 287 GLSDWLYEEEILKTHIAHWWSPDGT----------RLAYAAINDSRVPIMELPTYTGSIY 336

Query: 328 KT-DSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGW 386
            T   Y YP+ GS+NP I+L +        G    T + E++ P      +  YI    W
Sbjct: 337 PTVKPYHYPKAGSENPSISLHVI-------GLNGPTHDLEMMPPDDPRMREY-YITMVKW 388

Query: 387 TRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVT 446
               K A   +L+R Q    L L      + + ++E++                     +
Sbjct: 389 ATSTKVA-VTWLNRAQNVSILTLCDATTGVCTKKHEDE---------------------S 426

Query: 447 NVWI---NVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSP 503
             W+   N   +F     S+   +  F+RA   + G    Y +T          S+P S 
Sbjct: 427 EAWLHRQNEEPVF-----SKDGRKFFFIRAIP-QGGRGKFYHITV-------SSSQPNSS 473

Query: 504 GEDEFKCPIKEEIALTSGEWEVLARHGSKIWV-NEETKLVYFQGTKDTPLEHHLYVVSYE 562
            ++          ++TSG+W+V     +KI   +E+   +YF  T+D P    LY  S  
Sbjct: 474 NDNIQ--------SITSGDWDV-----TKILAYDEKGNKIYFLSTEDLPRRRQLY--SAN 518

Query: 563 AAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPD------DDPLHK 616
             G   R        SC + +N   F + +S         + K  GP        +   K
Sbjct: 519 TVGNFNRQCL-----SCDLVENCTYFSASFSHSMD---FFLLKCEGPGVPMVTVHNTTDK 570

Query: 617 QPRFWASMME-AASCPPDYVPPEIFHFHTR-SDVRLYGMIYKPHALQPGKKHPTVLFVYG 674
           +  F     E       D   P++ +      D  L   I KP        +P +L V G
Sbjct: 571 KKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDG 630

Query: 675 GPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQ 734
            P  Q V   F+ + +  +  ++S G  VV  DGRGS  +G +    ++ ++G +E +DQ
Sbjct: 631 TPGSQSVAEKFE-VSWETV-MVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQ 688

Query: 735 VEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKP----QVFKVAIAGAPVTVWMA 790
           +E ++ + ++  +ID +RVA+ G  YGG+LS   L  K     Q F    A +P+T +  
Sbjct: 689 MEAVRTMLKEQ-YIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKL 747

Query: 791 YDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVS 850
           Y + ++ERY+ +   +   YE   VA  V  L  E  + LI+H   DE +HF HT  L++
Sbjct: 748 YASAFSERYLGLHGLDNRAYEMTKVAHRVSAL--EEQQFLIIHPTADEKIHFQHTAELIT 805

Query: 851 QLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQE 890
           QLIR    Y LQIYP+E H        +H   ++++F  E
Sbjct: 806 QLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINFFVE 845


>gi|16933540 fibroblast activation protein, alpha subunit [Homo
           sapiens]
          Length = 760

 Score =  137 bits (346), Expect = 3e-32
 Identities = 150/633 (23%), Positives = 263/633 (41%), Gaps = 84/633 (13%)

Query: 269 GVATFVIQEEFDRFTGY--WWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEE 326
           G+  +V +EE    T Y  WW P   +          + Y E +++++ VI       E+
Sbjct: 195 GIPDWVYEEEM-LATKYALWWSPNGKF----------LAYAEFNDTDIPVIAYSYYGDEQ 243

Query: 327 R-KTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAG 385
             +T +  YP+ G+KNP + + + +    +    V  QE  +    +S      Y +   
Sbjct: 244 YPRTINIPYPKAGAKNPVVRIFIID---TTYPAYVGPQEVPVPAMIAS---SDYYFSWLT 297

Query: 386 WTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEV 445
           W  D +           QWL+ V     L I     + Q     +      Q ++  EE 
Sbjct: 298 WVTDERVCL--------QWLKRVQNVSVLSICDFREDWQTWDCPKT-----QEHI--EES 342

Query: 446 TNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGE 505
              W     +  P       D + + +    K G+ H++ +                   
Sbjct: 343 RTGWAGGFFVSTPV---FSYDAISYYKIFSDKDGYKHIHYI------------------- 380

Query: 506 DEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAA 564
              K  ++  I +TSG+WE +      I+   +  L Y     ++ P   ++Y +S  + 
Sbjct: 381 ---KDTVENAIQITSGKWEAI-----NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSY 432

Query: 565 GEIVRLTTPGF-SHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWA 622
               +  T       C   + +F  +  +Y+ V   P + +  L    D    ++ +   
Sbjct: 433 PPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLH---DGRTDQEIKILE 489

Query: 623 SMMEAASCPPDY-VPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLV 681
              E  +   +  +P E        ++ L+  +  P      KK+P ++ VYGGP  Q V
Sbjct: 490 ENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSV 549

Query: 682 NNSF--KGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQ 739
            + F    I YL     +  G  + ++DGRG+  +G +   A+  ++G  E+EDQ+  ++
Sbjct: 550 RSVFAVNWISYLA----SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVR 605

Query: 740 FVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERY 799
              E  GFID  R+AI GWSYGG++S + L     +FK  IA APV+ W  Y + YTER+
Sbjct: 606 KFIEM-GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERF 664

Query: 800 MDVP--ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGK 857
           M +P  ++N   Y+  +V    E   N     L++HG  D+NVHF ++  +   L+ A  
Sbjct: 665 MGLPTKDDNLEHYKNSTVMARAEYFRNVD--YLLIHGTADDNVHFQNSAQIAKALVNAQV 722

Query: 858 PYQLQIYPNERHSIRCPESGEHYEVTLLHFLQE 890
            +Q   Y ++ H +    S  H    + HFL++
Sbjct: 723 DFQAMWYSDQNHGL-SGLSTNHLYTHMTHFLKQ 754


>gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
          Length = 732

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 86/335 (25%), Positives = 147/335 (43%), Gaps = 49/335 (14%)

Query: 565 GEIVRLTTPGFSHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWAS 623
           G +  LT  G   S  + + + D+ V+ +S+ S PP + V  L     +    Q   W S
Sbjct: 396 GTVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPTLKVGFLPSAGKE----QSVLWVS 451

Query: 624 MMEAASCPPDY-------VPPEIFHFHTRSDVRLYGMIYKPHALQPGK-----KHPTVLF 671
           + EA   P  +        PPE      + +V+  G+ ++   LQPG      + P V+ 
Sbjct: 452 LEEAEPIPDIHWGIRVLQPPPE------QENVQYAGLDFEAILLQPGSPPDKTQVPMVVM 505

Query: 672 VYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEI 731
            +GGP     ++SF     L    L  +G+AV++++ RGS   G     +L   +G  ++
Sbjct: 506 PHGGP-----HSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDV 560

Query: 732 EDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAY 791
           +D    ++ V ++  F D S VA+ G S+GGF+S   +   P+ ++  +A  PV + +A 
Sbjct: 561 KDVQFAVEQVLQEEHF-DASHVALMGGSHGGFISCHLIGQYPETYRACVARNPV-INIAS 618

Query: 792 DTGYTERYMDVPE--NNQHGYEAGS-----VALHVEKLPNEPNR--------LLILHGFL 836
             G T    D+P+    + G+   S     +++  E L   P R        LL++ G  
Sbjct: 619 MLGST----DIPDWCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYIPQVKTPLLLMLGQE 674

Query: 837 DENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSI 871
           D  V F         L     P +L +YP   H++
Sbjct: 675 DRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHAL 709


>gi|41349456 prolyl endopeptidase [Homo sapiens]
          Length = 710

 Score = 37.4 bits (85), Expect = 0.063
 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 16/170 (9%)

Query: 617 QPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGP 676
           +PR +  +        DY   +IF + ++   ++   I     ++    HP  L+ YGG 
Sbjct: 418 EPRVFREVTVKGIDASDYQTVQIF-YPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGF 476

Query: 677 QVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFE--GALKNQMGQVEIEDQ 734
            + +  N        RL  +  +G  + V + RG  + G  +   G L N+      ++ 
Sbjct: 477 NISITPN----YSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANK------QNC 526

Query: 735 VEGLQFVAE---KYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIA 781
            +  Q  AE   K G+    R+ I+G S GG L       +P +F   IA
Sbjct: 527 FDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIA 576


>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
          Length = 816

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 20/150 (13%)

Query: 650 LYGMIYKP---HALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVI 706
           LY  IY P      +   K P +++++GG  ++   N   G      + LAS G  +V+ 
Sbjct: 147 LYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDG------SILASYGNVIVIT 200

Query: 707 DGRGSCQRGLRFEGALKNQ--MGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHGWSYG- 761
               +C+ G+    +  +Q   G   + DQ++ L+++ E  G    D  RV I G   G 
Sbjct: 201 I---NCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGA 257

Query: 762 GFLSLMGLIHKPQ-VFKVAI--AGAPVTVW 788
             +SL+ L H  + +F+ AI  +G  ++ W
Sbjct: 258 SCVSLLTLSHYSEGLFQKAIIQSGTALSSW 287


>gi|30840978 neuroligin 2 [Homo sapiens]
          Length = 835

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 14/133 (10%)

Query: 662 PGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGA 721
           PGKK P +LF++GG  ++   N F G      + LA+ G  +V          G    G 
Sbjct: 174 PGKK-PVMLFLHGGSYMEGTGNMFDG------SVLAAYGNVIVATLNYRLGVLGFLSTGD 226

Query: 722 LKNQMGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHGWSYG-GFLSLMGLIHKPQ-VFK 777
            +   G   + DQ++ L++++E       D  R+ I G   G   ++L+ L H  + +F+
Sbjct: 227 -QAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQ 285

Query: 778 VAIA--GAPVTVW 788
            AIA  G  ++ W
Sbjct: 286 KAIAQSGTAISSW 298


>gi|33563374 carboxylesterase 3 [Homo sapiens]
          Length = 571

 Score = 33.5 bits (75), Expect = 0.90
 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 22/180 (12%)

Query: 608 GPDDDPLHKQPRFWASMMEAASCPP----DYVPPEIFHFHTRSDVRLYGM--------IY 655
           GPD        + W  + +A++ PP    D        F      +++ +        +Y
Sbjct: 71  GPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVY 130

Query: 656 KPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRG 715
            P  +  G   P +++V+GG  +     S+ G      + LA+ G  VVV         G
Sbjct: 131 SPAEVPAGSGRPVMVWVHGGALITGAATSYDG------SALAAYGDVVVVTVQYRLGVLG 184

Query: 716 LRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHGWSYGGFLSLMGLIHKP 773
             F    ++  G     D V  L++V E       DL+ V + G S GG + + GL+  P
Sbjct: 185 F-FSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSI-ISGLVLSP 242


>gi|4758878 platelet-activating factor acetylhydrolase 2 [Homo
           sapiens]
          Length = 392

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 5/53 (9%)

Query: 737 GLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWM 789
           GL  +  K G ID+SRVA+ G S+GG  +++ L  + Q F+ A+A   +  WM
Sbjct: 215 GLDLMTLK-GNIDMSRVAVMGHSFGGATAILALAKETQ-FRCAVA---LDAWM 262


>gi|122939159 peptidyl arginine deiminase, type II [Homo sapiens]
          Length = 665

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 15/90 (16%)

Query: 197 NGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVAN-IETGEERRLTFCH 255
           N   +  +K L  KT C     + K+C      F ++N  D W+ + IE G    +   H
Sbjct: 317 NYLFLKEVKNLVEKTNC-----ELKVC------FQYLNRGDRWIQDEIEFGY---IEAPH 362

Query: 256 QGLSNVLDDPKSAGVATFVIQEEFDRFTGY 285
           +G   VLD P+   +  F ++E      GY
Sbjct: 363 KGFPVVLDSPRDGNLKDFPVKELLGPDFGY 392


>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
          Length = 607

 Score = 32.0 bits (71), Expect = 2.6
 Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 10/136 (7%)

Query: 640 FHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASL 699
           F   + S+  LY  IY P     G   P +++++GG  V  + + + G      + LA+L
Sbjct: 178 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDG------SMLAAL 231

Query: 700 GYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHG 757
              VVVI        G  F    K+  G     DQV  L++V +       +  RV I G
Sbjct: 232 ENVVVVIIQYRLGVLGF-FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFG 290

Query: 758 WSYGGFLSLMGLIHKP 773
            S GG  S+  L+  P
Sbjct: 291 ESAGG-TSVSSLVVSP 305


>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
          Length = 623

 Score = 32.0 bits (71), Expect = 2.6
 Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 10/136 (7%)

Query: 640 FHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASL 699
           F   + S+  LY  IY P     G   P +++++GG  V  + + + G      + LA+L
Sbjct: 178 FPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDG------SMLAAL 231

Query: 700 GYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFI--DLSRVAIHG 757
              VVVI        G  F    K+  G     DQV  L++V +       +  RV I G
Sbjct: 232 ENVVVVIIQYRLGVLGF-FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFG 290

Query: 758 WSYGGFLSLMGLIHKP 773
            S GG  S+  L+  P
Sbjct: 291 ESAGG-TSVSSLVVSP 305


>gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]
          Length = 490

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 167 GITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPAD 226
           GI    F + SG   F+ S + FHC+DG K       +              D  IC  +
Sbjct: 61  GIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQE 120

Query: 227 PAFFSFINNSDLWVANIETGEERRLTFCHQG 257
                 I ++++       GE+  +T CH+G
Sbjct: 121 DCRIPQIEDAEIHNKTYRHGEKLIIT-CHEG 150


>gi|81295416 sushi domain containing 4 isoform b [Homo sapiens]
          Length = 290

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 167 GITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPAD 226
           GI    F + SG   F+ S + FHC+DG K       +              D  IC  +
Sbjct: 61  GIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQE 120

Query: 227 PAFFSFINNSDLWVANIETGEERRLTFCHQG 257
                 I ++++       GE+  +T CH+G
Sbjct: 121 DCRIPQIEDAEIHNKTYRHGEKLIIT-CHEG 150


>gi|40254439 endothelial PAS domain protein 1 [Homo sapiens]
          Length = 870

 Score = 30.8 bits (68), Expect = 5.9
 Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 17/77 (22%)

Query: 587 MFVSHYSSVSTPPC-----VHVYKLSG------PDDDPLHKQPRFWA------SMMEAAS 629
           +F    S  S PPC       +  + G      P D PLH  P  WA        + AA 
Sbjct: 607 IFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAP 666

Query: 630 CPPDYVPPEIFHFHTRS 646
             P   PP +  F TRS
Sbjct: 667 LGPPVSPPHVSTFKTRS 683


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score = 30.0 bits (66), Expect = 10.0
 Identities = 16/47 (34%), Positives = 25/47 (53%)

Query: 307 EEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQT 353
           EE+DES+ ++   PSP  +ER      +  + S +P+  L L  F T
Sbjct: 712 EEIDESDDDLDDKPSPIKKERSPRPQSFCHSSSISPQDKLALPGFST 758


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,668,985
Number of Sequences: 37866
Number of extensions: 1790839
Number of successful extensions: 3543
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3480
Number of HSP's gapped (non-prelim): 40
length of query: 892
length of database: 18,247,518
effective HSP length: 111
effective length of query: 781
effective length of database: 14,044,392
effective search space: 10968670152
effective search space used: 10968670152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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