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Search of human proteins with 192448440
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|192448440 sialyltransferase 7B [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|192448440 sialyltransferase 7B [Homo sapiens] 775 0.0
gi|21264332 sialyltransferase 7A [Homo sapiens] 252 3e-67
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 97 3e-20
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 92 1e-18
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 92 1e-18
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 80 3e-15
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 80 3e-15
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 80 3e-15
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 80 3e-15
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 80 3e-15
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 80 3e-15
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 73 4e-13
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 71 2e-12
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 71 2e-12
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 69 5e-12
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 69 5e-12
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 69 9e-12
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 67 2e-11
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 67 3e-11
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 63 4e-10
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 61 2e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 61 2e-09
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 60 4e-09
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 55 1e-07
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 54 3e-07
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 54 3e-07
gi|13569938 sialyltransferase 7E [Homo sapiens] 52 9e-07
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 50 3e-06
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 49 1e-05
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 45 1e-04
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 775 bits (2002), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWT 60
MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWT
Sbjct: 1 MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWT 60
Query: 61 GKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQ 120
GKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQ
Sbjct: 61 GKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQ 120
Query: 121 VIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNG 180
VIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNG
Sbjct: 121 VIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNG 180
Query: 181 AVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVML 240
AVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVML
Sbjct: 181 AVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVML 240
Query: 241 RSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDL 300
RSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDL
Sbjct: 241 RSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDL 300
Query: 301 YMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALW 360
YMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALW
Sbjct: 301 YMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALW 360
Query: 361 RDLHKAGILQLYQR 374
RDLHKAGILQLYQR
Sbjct: 361 RDLHKAGILQLYQR 374
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 252 bits (644), Expect = 3e-67
Identities = 135/330 (40%), Positives = 190/330 (57%), Gaps = 9/330 (2%)
Query: 51 FQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKA 110
F+ K S G C + + + + LF ++ + L F + WDRL
Sbjct: 264 FEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAP 323
Query: 111 PYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPP-KCIRCAVVGNGGILNGSRQGPNI 169
P+G+ L++ ++ ++ +L +CI CAVVGNGGILN S G I
Sbjct: 324 PFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEI 383
Query: 170 DAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIF 229
D+HDYVFRL+GA+IKG+E+DVGT+TSFYGFT ++ SL+ N GF +VP G+D++Y+
Sbjct: 384 DSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLH 443
Query: 230 IPSDIRDYVMLRSAILGVPVPEGLDKG-----DRPHAYFGPEASASKFKLLHPDFISYLT 284
RDY L + ++ V + K RP F ++ LLHPDF+ Y+
Sbjct: 444 FLEGTRDYEWLEALLMNQTV---MSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMK 500
Query: 285 ERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKP 344
RFL+SK ++ +Y P+TGAL+LLTAL CDQVSAYGFIT + +FSDHY++ K
Sbjct: 501 NRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKR 560
Query: 345 LIFYANHDLSLEAALWRDLHKAGILQLYQR 374
LIFY NHD LE +W+ LH GI++LYQR
Sbjct: 561 LIFYINHDFKLEREVWKRLHDEGIIRLYQR 590
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 96.7 bits (239), Expect = 3e-20
Identities = 102/381 (26%), Positives = 162/381 (42%), Gaps = 55/381 (14%)
Query: 8 FFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFE------AFFQSKASNSWTG 61
+F + L LLF ++ P +GA D T A Q + +G
Sbjct: 8 WFLSVAFLLVFIMSLLFTYSHHSMATLPYLDSGALDGTHRVKLVPGYAGLQRLSKERLSG 67
Query: 62 KGQACRHLLHLAIQRH---PHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLS 118
K ACR + A HF G N+S PV ++ P R P +
Sbjct: 68 KSCACRRCMGDAGASDWFDSHFDG--NIS-PVWTRENMDLPPDVQRWWMMLQPQFKSHNT 124
Query: 119 HQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRL 178
++V+ ++ G + RD P +C RCAVVGN G L GS G ++D H+++ R+
Sbjct: 125 NEVLEKLFQIVPGENPYRF----RD-PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRM 179
Query: 179 NGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYV 238
N A GFE+DVG++T+ + + KN +P ++ ++ +P + D +
Sbjct: 180 NQAPTVGFEQDVGSRTTHHFMYPESAKN------------LP--ANVSFVLVPFKVLDLL 225
Query: 239 MLRSAILGVPVPEGLDKGDRPHAYFGPEA----SASKFKLLHPDFISYLTERFLKSKLIN 294
+ SA L G Y ++ K ++ +P F Y+ +R+ +
Sbjct: 226 WIASA---------LSTGQIRFTYAPVKSFLRVDKEKVQIYNPAFFKYIHDRWTE----- 271
Query: 295 THFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYAN--HD 352
H G PSTG L+L ALH CD+V+ YGF + + HY+E F HD
Sbjct: 272 -HHG--RYPSTGMLVLFFALHVCDEVNVYGFGADSRGNW-HHYWENNRYAGEFRKTGVHD 327
Query: 353 LSLEAALWRDLHKAGILQLYQ 373
EA + L KA +++Y+
Sbjct: 328 ADFEAHIIDMLAKASKIEVYR 348
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 91.7 bits (226), Expect = 1e-18
Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 38/232 (16%)
Query: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNS 207
C RCAVVGN G L S GP ID+HD+V R+N A GFE DVGTKT+ + + +
Sbjct: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRE- 197
Query: 208 LVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEA 267
G ++ I +P D + SAI G H Y A
Sbjct: 198 -------------LGDNVSMILVPFKTIDLEWVVSAI---------TTGTISHTYIPVPA 235
Query: 268 ----SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
K + HP FI Y+ + +L+ G PSTG L ++ ++H CD+V Y
Sbjct: 236 KIRVKQDKILIYHPAFIKYVFDNWLQ--------GHGRYPSTGILSVIFSMHVCDEVDLY 287
Query: 324 GFITSNYWKFSDHYFERKMKPLIFYAN--HDLSLEAALWRDLHKAGILQLYQ 373
GF + + HY+E F HD E+ + L +++++
Sbjct: 288 GFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 91.7 bits (226), Expect = 1e-18
Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 38/232 (16%)
Query: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNS 207
C RCAVVGN G L S GP ID+HD+V R+N A GFE DVGTKT+ + + +
Sbjct: 139 CRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRE- 197
Query: 208 LVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEA 267
G ++ I +P D + SAI G H Y A
Sbjct: 198 -------------LGDNVSMILVPFKTIDLEWVVSAI---------TTGTISHTYIPVPA 235
Query: 268 ----SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
K + HP FI Y+ + +L+ G PSTG L ++ ++H CD+V Y
Sbjct: 236 KIRVKQDKILIYHPAFIKYVFDNWLQ--------GHGRYPSTGILSVIFSMHVCDEVDLY 287
Query: 324 GFITSNYWKFSDHYFERKMKPLIFYAN--HDLSLEAALWRDLHKAGILQLYQ 373
GF + + HY+E F HD E+ + L +++++
Sbjct: 288 GFGADSKGNW-HHYWENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFK 338
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 155 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 208
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 209 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 256
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 257 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 312
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 313 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 372
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 373 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 406
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 101 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 154
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 155 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 202
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 203 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 258
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 259 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 318
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 319 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 352
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 171 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 224
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 225 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 272
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 273 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 328
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 329 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 388
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 389 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 422
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 132 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 185
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 186 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 233
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 234 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 289
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 290 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 349
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 350 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 383
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 186 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 239
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 240 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 287
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 288 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 343
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 344 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 403
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 404 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 437
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 80.1 bits (196), Expect = 3e-15
Identities = 73/274 (26%), Positives = 125/274 (45%), Gaps = 28/274 (10%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 117 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 170
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQ 221
G ID +D V RLN A +KGFE+DVG+KT+ ++Y G P+
Sbjct: 171 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLR-----------ITYPE-GAMQRPE 218
Query: 222 GQDLQYIFIPSDIR--DYVMLRSAILG--VPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
+ +F+ + + D+ L+ + V +G K P + ++L+P
Sbjct: 219 QYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPP----EIRILNP 274
Query: 278 DFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDH 336
FI + N G +P+ G++ + ALH CD+V+ GF + H
Sbjct: 275 YFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLH 334
Query: 337 YFER-KMKPLIFYANHDLSLEAALWRDLHKAGIL 369
Y+E +M + H++ E R L KA ++
Sbjct: 335 YYETVRMAAIKESWTHNIQREKEFLRKLVKARVI 368
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 73.2 bits (178), Expect = 4e-13
Identities = 63/267 (23%), Positives = 116/267 (43%), Gaps = 22/267 (8%)
Query: 106 SQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQ 165
S ++ PYG +G S ++ L++ + S P +C RC VVGNG L S
Sbjct: 78 SAYELPYGTKG-SEDLLLRVLAITSSS------IPKNIQSLRCRRCVVVGNGHRLRNSSL 130
Query: 166 GPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDL 225
G I+ +D V RLN A + G+E DVG+KT+ F + V D
Sbjct: 131 GDAINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPESAHFD---------PKVENNPDT 181
Query: 226 QYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTE 285
+ + D+ + + + + + KG + + + ++L+P F+ +
Sbjct: 182 LLVLVAFKAMDFHWIETILSD---KKRVRKGFWKQPPLIWDVNPKQIRILNPFFMEIAAD 238
Query: 286 RFLKSKLINTHFGDLYMPSTGALMLLTALHTCD--QVSAYGFITSNYWKFSDHYFERKMK 343
+ L + P+TG L + ALH CD ++ +G+ + K + HY+E+
Sbjct: 239 KLLSLPMQQPR-KIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYEQITL 297
Query: 344 PLIFYANHDLSLEAALWRDLHKAGILQ 370
+ + H++S EA + + + G ++
Sbjct: 298 KSMAGSGHNVSQEALAIKRMLEMGAIK 324
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 70.9 bits (172), Expect = 2e-12
Identities = 69/236 (29%), Positives = 97/236 (41%), Gaps = 38/236 (16%)
Query: 151 CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVS 210
CAVVGN GIL GS+ G ID D+VFR N A + F+RDVG KT+ F + ++
Sbjct: 162 CAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILE----K 217
Query: 211 YWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHA---YFGPEA 267
Y+N T QD F+ L AIL +P +F
Sbjct: 218 YYNNLLTI----QDRNNFFL-----SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHR 268
Query: 268 SASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFIT 327
K +L P I R+ K+K ++ STG LM A C+++ YGF
Sbjct: 269 GQLKVQLAWPGNIMQHVNRYWKNKHLSPK-----RLSTGILMYTLASAICEEIHLYGF-- 321
Query: 328 SNYWKFS----------DHYFERKMKPLI--FYANHDLSLEAALWRDLHKAGILQL 371
W F HY+++K + +H L E L +H G+ +L
Sbjct: 322 ---WPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKL 374
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 70.9 bits (172), Expect = 2e-12
Identities = 77/287 (26%), Positives = 128/287 (44%), Gaps = 57/287 (19%)
Query: 106 SQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTP---PKCIRCAVVGNGGILNG 162
+Q P G + L ++V S + +N E ++F P+D P + +CAVVGNGGIL
Sbjct: 120 TQKNTPLGTK-LKYEVDTSGIYHIN-QEIFRMF--PKDMPYYRSQFKKCAVVGNGGILKN 175
Query: 163 SRQGPNIDAHDYVFRLN-GAVIKGFERDVGTKTSFYGFTVN----TMKNSLVSYWNLGFT 217
SR G I++ D+VFR N + + + DVG KT TVN T + + W F
Sbjct: 176 SRCGREINSADFVFRCNLPPISEKYTMDVGVKTDV--VTVNPSIITERFHKLEKWRRPFY 233
Query: 218 SVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHP 277
V Q + + +P+ + R+ + + V LD + P A + HP
Sbjct: 234 RVLQVYENASVLLPA----FYNTRNTDVSIRVKYVLDDFESPQAVY----------YFHP 279
Query: 278 DFISYLTERFL----KSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKF 333
++ ++ +L ++K I STG +++ AL C++V +GF W F
Sbjct: 280 QYLVNVSRYWLSLGVRAKRI----------STGLILVTAALELCEEVHLFGF-----WAF 324
Query: 334 S--------DHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLY 372
H++ +KP + H + E + LH GIL+++
Sbjct: 325 PMNPSGLYITHHYYDNVKPRPGF--HAMPSEIFNFLHLHSRGILRVH 369
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 69.3 bits (168), Expect = 5e-12
Identities = 69/274 (25%), Positives = 117/274 (42%), Gaps = 30/274 (10%)
Query: 106 SQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPK-----CIRCAVVGNGGIL 160
S++ P+G+R S +V + L LL P D P C RC V+G+GGIL
Sbjct: 133 SKYDPPFGFRKFSSKV-QTLLELL----------PEHDLPEHLKAKTCRRCVVIGSGGIL 181
Query: 161 NGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVP 220
+G G ++ D V RLN A ++G+ VG KT+ S + Y++
Sbjct: 182 HGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYS------- 234
Query: 221 QGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFI 280
DL ++ + D+ L++ + +P + F++L+P I
Sbjct: 235 --NDL-FVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVII 291
Query: 281 SYLTERFLKSKLINTHF--GDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDHY 337
L+ + F D +P+ G + ++ A H CD+VS GF N + HY
Sbjct: 292 KETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHY 351
Query: 338 FERK-MKPLIFYANHDLSLEAALWRDLHKAGILQ 370
F+ + M + F H+++ E L K G+++
Sbjct: 352 FDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVK 385
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 69.3 bits (168), Expect = 5e-12
Identities = 69/274 (25%), Positives = 117/274 (42%), Gaps = 30/274 (10%)
Query: 106 SQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPK-----CIRCAVVGNGGIL 160
S++ P+G+R S +V + L LL P D P C RC V+G+GGIL
Sbjct: 156 SKYDPPFGFRKFSSKV-QTLLELL----------PEHDLPEHLKAKTCRRCVVIGSGGIL 204
Query: 161 NGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVP 220
+G G ++ D V RLN A ++G+ VG KT+ S + Y++
Sbjct: 205 HGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYS------- 257
Query: 221 QGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFI 280
DL ++ + D+ L++ + +P + F++L+P I
Sbjct: 258 --NDL-FVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVII 314
Query: 281 SYLTERFLKSKLINTHF--GDLYMPSTGALMLLTALHTCDQVSAYGF-ITSNYWKFSDHY 337
L+ + F D +P+ G + ++ A H CD+VS GF N + HY
Sbjct: 315 KETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHY 374
Query: 338 FERK-MKPLIFYANHDLSLEAALWRDLHKAGILQ 370
F+ + M + F H+++ E L K G+++
Sbjct: 375 FDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVK 408
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 68.6 bits (166), Expect = 9e-12
Identities = 73/235 (31%), Positives = 106/235 (45%), Gaps = 42/235 (17%)
Query: 150 RCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKG-FERDVGTKTSFYGFTVNTMKNSL 208
+CAVVGNGGILN S G ID D+VFR N G +DVG+KT+ T+N +L
Sbjct: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNL--VTINPSIITL 242
Query: 209 VSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPV-PEGLDKGDRPHAYFGPEA 267
Y NL ++ + +F+ DI Y A +P + G Y+ E
Sbjct: 243 -KYGNL--------KEKKALFL-EDIATY---GDAFFLLPAFSFRANTGTSFKVYYTLEE 289
Query: 268 SASKFKLL--HPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF 325
S ++ K+L HP ++ L F ++K + Y STG ++ A+ C V YGF
Sbjct: 290 SKARQKVLFFHPKYLKDLA-LFWRTKGVTA-----YRLSTGLMITSVAVELCKNVKLYGF 343
Query: 326 ITSNYWKF---------SDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQL 371
W F S HY++ K+ + H + E + LH GIL+L
Sbjct: 344 -----WPFSKTVEDIPVSHHYYDNKLPK---HGFHQMPKEYSQILQLHMKGILKL 390
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 6/94 (6%)
Query: 102 WDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILN 161
W R+ + P+G +G + + A +L+ ++ +L P D+ +C RC +VGNGG+L
Sbjct: 117 WARIREFVPPFGIKGQDNLIKA----ILSVTKEYRL-TPALDSL-RCRRCIIVGNGGVLA 170
Query: 162 GSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTS 195
G ID +D V RLN A +KGFE+DVG+KT+
Sbjct: 171 NKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTT 204
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 66.6 bits (161), Expect = 3e-11
Identities = 68/236 (28%), Positives = 98/236 (41%), Gaps = 41/236 (17%)
Query: 151 CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVS 210
CAVVGN GIL S G ID+H++V R N A + F DVGTK+ F TM S+V
Sbjct: 142 CAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFI-----TMNPSVVQ 196
Query: 211 YWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPE---A 267
GF + + + ML ++L +P + KG H +
Sbjct: 197 RAFGGFRNESDREKF--------VHRLSMLNDSVLWIPA--FMVKGGEKHVEWVNALILK 246
Query: 268 SASKFKLLHPD--FISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF 325
+ K + +P I + +L +K+ + PSTG LM A CD++ YGF
Sbjct: 247 NKLKVRTAYPSLRLIHAVRGYWLTNKV------PIKRPSTGLLMYTLATRFCDEIHLYGF 300
Query: 326 ITSNYWKFSD---------HYF-ERKMKPLIFYANHDLSLEAALWRDLHKAGILQL 371
W F HY+ + K + + H + LE LH G L+L
Sbjct: 301 -----WPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKL 351
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 63.2 bits (152), Expect = 4e-10
Identities = 65/246 (26%), Positives = 102/246 (41%), Gaps = 30/246 (12%)
Query: 111 PYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNID 170
PYG R S + LS L +S LF + P C +C VVGNGG+L G ID
Sbjct: 84 PYGMR-TSAEYFRLALSKL---QSCDLFDEFDNIP--CKKCVVVGNGGVLKNKTLGEKID 137
Query: 171 AHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFI 230
++D + R+N + G E +VG +T+F F ++ + + + P + F
Sbjct: 138 SYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIH-------NDPNTTVILTAFK 190
Query: 231 PSDIRDYVMLRSAILGVPV-PEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLK 289
P D+R L ++G + G K + + P + ++L P I L
Sbjct: 191 PHDLR---WLLELLMGDKINTNGFWKKPALNLIYKP----YQIRILDPFIIRTAAYELLH 243
Query: 290 SKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYA 349
+ P+TG + + A + C +V GF + FSD PL +Y
Sbjct: 244 FPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGF----KYNFSD-----LKSPLHYYG 294
Query: 350 NHDLSL 355
N +SL
Sbjct: 295 NATMSL 300
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 27/197 (13%)
Query: 150 RCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLV 209
RCAVV + G L S+ G ID HD V R NGA F++DVGTKT T+ M + LV
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKT-----TIRLMNSQLV 237
Query: 210 SYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASA 269
+ + + ++ PS + +P+ D + +F +
Sbjct: 238 TTEKRFLKDSLYNEGILIVWDPS-----------VYHSDIPKWYQNPD--YNFFN---NY 281
Query: 270 SKFKLLHPDFISYLTERFLKSKL------INTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
++ LHP+ Y+ + + +L I+ PS+G L ++ + CDQV Y
Sbjct: 282 KTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIY 341
Query: 324 GFITSNYWKFSDHYFER 340
F+ S +Y+++
Sbjct: 342 EFLPSKRKTDVCYYYQK 358
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 27/197 (13%)
Query: 150 RCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLV 209
RCAVV + G L S+ G ID HD V R NGA F++DVGTKT T+ M + LV
Sbjct: 183 RCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKT-----TIRLMNSQLV 237
Query: 210 SYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASA 269
+ + + ++ PS + +P+ D + +F +
Sbjct: 238 TTEKRFLKDSLYNEGILIVWDPS-----------VYHSDIPKWYQNPD--YNFFN---NY 281
Query: 270 SKFKLLHPDFISYLTERFLKSKL------INTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
++ LHP+ Y+ + + +L I+ PS+G L ++ + CDQV Y
Sbjct: 282 KTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIY 341
Query: 324 GFITSNYWKFSDHYFER 340
F+ S +Y+++
Sbjct: 342 EFLPSKRKTDVCYYYQK 358
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 59.7 bits (143), Expect = 4e-09
Identities = 64/247 (25%), Positives = 96/247 (38%), Gaps = 40/247 (16%)
Query: 141 PRDTPPKCIR---CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFY 197
PR +P K CA+VGN G+L S G IDAH +V R N A ++ + RDVG KT
Sbjct: 144 PRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLV 203
Query: 198 GFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGD 257
TM S++ + + L ++ L +IL +P +
Sbjct: 204 -----TMNPSVIQRAFEDLVNATWREKL--------LQRLHSLNGSILWIPAFMARGGKE 250
Query: 258 RPH--------AYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALM 309
R + + +LLH +LT + + P+TG LM
Sbjct: 251 RVEWVNELILKHHVNVRTAYPSLRLLHAVRGYWLTNKV-----------HIKRPTTGLLM 299
Query: 310 LLTALHTCDQVSAYGF----ITSNYWKFSDHYFERKMKPLIFYAN-HDLSLEAALWRDLH 364
A C Q+ YGF + N HY++ A+ H + LE + LH
Sbjct: 300 YTLATRFCKQIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLH 359
Query: 365 KAGILQL 371
+ G L+L
Sbjct: 360 EQGALKL 366
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 55.1 bits (131), Expect = 1e-07
Identities = 61/240 (25%), Positives = 105/240 (43%), Gaps = 32/240 (13%)
Query: 139 APPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKG-FERDVGTKTSFY 197
A P P K +CAVVGNGGIL S G ID ++V R N + + +DVG+K+
Sbjct: 128 ATPFQLPLK--KCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV 185
Query: 198 GFTVNTMKNSLVS-YWN-LGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDK 255
+ ++ + W+ F + + YI++P+ + G +
Sbjct: 186 TANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPA--------------FSMKTGTEP 231
Query: 256 GDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALH 315
R + + +P+F+ + +F KS+ I+ STG ++ AL
Sbjct: 232 SLRVYYTLSDVGANQTVLFANPNFLRSI-GKFWKSRGIHAK-----RLSTGLFLVSAALG 285
Query: 316 TCDQVSAYGF----ITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQL 371
C++V+ YGF + + S HY++ + F+A + L+ LW LHK G L++
Sbjct: 286 LCEEVAIYGFWPFSVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQ--LWY-LHKIGALRM 342
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 53.5 bits (127), Expect = 3e-07
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 21/198 (10%)
Query: 146 PKCIR-CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTM 204
P+ +R CAVV + G + S G ID+HD V R N A +G+E+DVG KT T+ +
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKT-----TIRII 344
Query: 205 KNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFG 264
+ +++ + F +D+ I + D Y SA L + + P+
Sbjct: 345 NSQILTNPSHHFIDSSLYKDV--ILVAWDPAPY----SANLNLWYKKPDYNLFTPYIQHR 398
Query: 265 PEASASKFKLLHPDFISYL---TERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVS 321
F +LHP FI L + K K+ PS+G + +L + C +V
Sbjct: 399 QRNPNQPFYILHPKFIWQLWDIIQENTKEKI------QPNPPSSGFIGILIMMSMCREVH 452
Query: 322 AYGFITSNYWKFSDHYFE 339
Y +I S HY E
Sbjct: 453 VYEYIPSVRQTELCHYHE 470
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 53.5 bits (127), Expect = 3e-07
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 21/198 (10%)
Query: 146 PKCIR-CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTM 204
P+ +R CAVV + G + S G ID+HD V R N A +G+E+DVG KT T+ +
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKT-----TIRII 344
Query: 205 KNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFG 264
+ +++ + F +D+ I + D Y SA L + + P+
Sbjct: 345 NSQILTNPSHHFIDSSLYKDV--ILVAWDPAPY----SANLNLWYKKPDYNLFTPYIQHR 398
Query: 265 PEASASKFKLLHPDFISYL---TERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVS 321
F +LHP FI L + K K+ PS+G + +L + C +V
Sbjct: 399 QRNPNQPFYILHPKFIWQLWDIIQENTKEKI------QPNPPSSGFIGILIMMSMCREVH 452
Query: 322 AYGFITSNYWKFSDHYFE 339
Y +I S HY E
Sbjct: 453 VYEYIPSVRQTELCHYHE 470
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 52.0 bits (123), Expect = 9e-07
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 25/193 (12%)
Query: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNS 207
C CA+V + G L SRQG ID + V R+N A +G+ RDVG +TS ++++
Sbjct: 93 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI 152
Query: 208 LVSYWNLGFTSVPQGQDLQY----IFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYF 263
L + +L +V QG + ++ D + V +L +P R A+
Sbjct: 153 LRNRHDL--LNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLP-------RLKAFM 203
Query: 264 GPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAY 323
++ K+L D + + E K+ NT STG + AL CD+++ Y
Sbjct: 204 -----ITRHKMLQFDEL-FKQETGKDRKISNTWL------STGWFTMTIALELCDRINVY 251
Query: 324 GFITSNYWKFSDH 336
G + ++ + +H
Sbjct: 252 GMVPPDFCRDPNH 264
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 50.1 bits (118), Expect = 3e-06
Identities = 50/232 (21%), Positives = 88/232 (37%), Gaps = 52/232 (22%)
Query: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSF----------- 196
C CAVV + G + GS G ID+ + VFR+N A GFE DVG +++
Sbjct: 73 CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 132
Query: 197 ---YGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGL 253
Y +++L W QG+ + + R + L G+ V
Sbjct: 133 LRNYSHYFQKARDTLYMVWG-------QGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFT 185
Query: 254 DKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTA 313
++ ++Y + F N ++ STG ++ A
Sbjct: 186 ER-----------------------MMAYCDQIFQDETGKNRRQSGSFL-STGWFTMILA 221
Query: 314 LHTCDQVSAYGFITSNYWKFSD------HYFER-KMKPLIFYANHDLSLEAA 358
L C+++ YG ++ +Y + HYFE+ ++ Y H+ + +A
Sbjct: 222 LELCEEIVVYGMVSDSYCREKSHPSVPYHYFEKGRLDECQMYLAHEQAPRSA 273
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/51 (47%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 146 PKCIR-CAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTS 195
P+ +R CAVV + G + S G ID+HD V R N A +G+E+DVG KT+
Sbjct: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTT 340
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 44.7 bits (104), Expect = 1e-04
Identities = 20/47 (42%), Positives = 27/47 (57%)
Query: 148 CIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKT 194
C CA+V N G + G + G ID ++R+N A KG+E DVG T
Sbjct: 77 CDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMT 123
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,968,613
Number of Sequences: 37866
Number of extensions: 679914
Number of successful extensions: 1761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1692
Number of HSP's gapped (non-prelim): 60
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.