Guide to the Human Genome
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Search of human proteins with 189571669

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189571669 sprouty-related protein with EVH-1 domain 2
isoform a [Homo sapiens]
         (418 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform...   899   0.0  
gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform...   882   0.0  
gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa...   427   e-120
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a...   272   5e-73
gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b ...   134   1e-31
gi|27501452 sprouty homolog 3 [Homo sapiens]                           70   3e-12
gi|56549694 enabled homolog isoform a [Homo sapiens]                   67   4e-11
gi|39930375 enabled homolog isoform b [Homo sapiens]                   67   4e-11
gi|5032115 sprouty 2 [Homo sapiens]                                    62   1e-09
gi|7706687 Enah/Vasp-like [Homo sapiens]                               62   1e-09
gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo...    60   5e-09
gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo...    60   5e-09
gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]                59   1e-08
gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]                 59   1e-08
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]        59   1e-08
gi|14210518 PAR-6 gamma protein [Homo sapiens]                         39   0.007
gi|7662022 lipin 2 [Homo sapiens]                                      33   0.63 
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti...    32   0.82 
gi|239750462 PREDICTED: similar to hCG2033802 [Homo sapiens]           32   1.1  
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]              31   2.4  
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]              31   2.4  
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]              31   2.4  
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]              31   2.4  
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]              31   2.4  
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]              31   2.4  
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]    31   2.4  
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]    31   2.4  
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    30   3.1  
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s...    30   4.1  
gi|15042949 PR domain containing 12 [Homo sapiens]                     30   4.1  

>gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a
           [Homo sapiens]
          Length = 418

 Score =  899 bits (2324), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIH 60
           MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIH
Sbjct: 1   MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIH 60

Query: 61  GERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIE 120
           GERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIE
Sbjct: 61  GERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIE 120

Query: 121 DLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTL 180
           DLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTL
Sbjct: 121 DLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTL 180

Query: 181 GHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKY 240
           GHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKY
Sbjct: 181 GHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKY 240

Query: 241 PDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRR 300
           PDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRR
Sbjct: 241 PDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRR 300

Query: 301 KEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD 360
           KEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD
Sbjct: 301 KEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD 360

Query: 361 YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 418
           YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
Sbjct: 361 YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 418


>gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b
           [Homo sapiens]
          Length = 415

 Score =  882 bits (2278), Expect = 0.0
 Identities = 410/412 (99%), Positives = 410/412 (99%)

Query: 7   PDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD 66
           P  DSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD
Sbjct: 4   PGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKD 63

Query: 67  KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS 126
           KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS
Sbjct: 64  KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGS 123

Query: 127 TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS 186
           TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS
Sbjct: 124 TTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDS 183

Query: 187 YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED 246
           YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED
Sbjct: 184 YPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSED 243

Query: 247 ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER 306
           ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER
Sbjct: 244 ADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGER 303

Query: 307 SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS 366
           SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS
Sbjct: 304 SRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS 363

Query: 367 CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 418
           CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
Sbjct: 364 CDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA 415


>gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo
           sapiens]
          Length = 444

 Score =  427 bits (1098), Expect = e-120
 Identities = 237/457 (51%), Positives = 289/457 (63%), Gaps = 54/457 (11%)

Query: 1   MTEETHP-DDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLI 59
           M+EET   D+D+   RV+AVVMTRDDSSGGW P  G G+S V V KV H E NG + F I
Sbjct: 1   MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFI 60

Query: 60  HGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAI 119
            GER +DK+VVLEC ++KDL+Y K  PTFHHWK+D++KFGLTFQSPADARAFDRG+R+AI
Sbjct: 61  RGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAI 120

Query: 120 EDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKR--EQPTRTISSPTSCEH--- 174
           ED+ +G   S     NEAE G DD+     DSSS+  +    +Q T   S P    +   
Sbjct: 121 EDISQGCPESK----NEAE-GADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRP 175

Query: 175 --------RRIYTLGHLHD----------------------SYPTDHYHLDQPMP-RPYR 203
                   RR+Y     +                       S           +P +  R
Sbjct: 176 SPFEDLNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIR 235

Query: 204 QVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSEDADSSYVRFAKGEVPKHD 263
            VSF D+DE IVRINPR+ I +  Y DYRH P   K     +DADSS ++F+K +  K D
Sbjct: 236 HVSFQDEDE-IVRINPRD-ILIRRYADYRH-PDMWKNDLERDDADSS-IQFSKPDSKKSD 291

Query: 264 YNYPYVDSSDFGLGEDPKGRGGSVIKTQPSR---GKSRRRKEDGERSRCVYCRDMFNHEE 320
           Y Y   D +     +D       V KTQPS     KS+RRKEDGERSRCVYC++ FNHEE
Sbjct: 292 YLYSCGDETKLSSPKD-----SVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEE 346

Query: 321 NRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMA 380
           N RG CQDAPD ++ CI +VSCM CA+SMLYHCMSD EGD++DPCSCDTSD+KFCLRW+A
Sbjct: 347 NVRGKCQDAPDPIKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLA 406

Query: 381 LIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAA 417
           L+ALSF+ PCMCCY+PLR C+ CG  C CCGGKHKAA
Sbjct: 407 LVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAA 443


>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
           [Homo sapiens]
          Length = 410

 Score =  272 bits (695), Expect = 5e-73
 Identities = 163/422 (38%), Positives = 220/422 (52%), Gaps = 29/422 (6%)

Query: 13  IVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVM--HPEGNGRSG-FLIHGERQKDKLV 69
           +VRV+AVVM RDDSSGGW P  GGG+S+V VC+V    PEG  R G ++IHGER +D+  
Sbjct: 1   MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60

Query: 70  VLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTS 129
            LEC ++  LVY K NP FHHW + + KFGLTFQSPA+A  F + +  A+  L  GS T 
Sbjct: 61  TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120

Query: 130 SSTIHNEAELGDDDV----FTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHD 185
           SS+  + +   D        T+  DS S+SS  R++      +P S     I T+     
Sbjct: 121 SSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQE------TPPSAAAAPIITMESASG 174

Query: 186 SYPTDHYHLDQPMPRPYRQV----SFPDDDEEIVRINPREKIWM-TGYEDYRHAPVRGKY 240
             PT      +   + Y  +      P+  E +         W   GYEDYR +      
Sbjct: 175 FGPTTPPQRRRSSAQSYPPLLPFTGIPEPSEPLAGAGGLG--WGGRGYEDYRRSG----- 227

Query: 241 PDPSEDADSSYVRFAK-GEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRR 299
           P       +  VRFAK G +       P    +       P           PS   ++ 
Sbjct: 228 PPAPLALSTCVVRFAKTGALRGAALGPPAALPAPLTEAAPPAPPARPPPGPGPSSAPAKA 287

Query: 300 RKEDGERSRCVYCRDMFNHE-ENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPE 358
             E  E +RCV+CR +F    + R G C +APD  R  +RR+SC+WCA+S+LYHC+SD E
Sbjct: 288 SPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAE 347

Query: 359 GDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRC--CGGKHKA 416
           GD++DPC+C+    +   RW AL ALS   PC+CCY PLRAC+     C C  CGG+H+ 
Sbjct: 348 GDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEE 407

Query: 417 AA 418
           AA
Sbjct: 408 AA 409


>gi|88853871 sprouty-related, EVH1 domain containing 3 isoform b
           [Homo sapiens]
          Length = 152

 Score =  134 bits (338), Expect = 1e-31
 Identities = 67/123 (54%), Positives = 85/123 (69%), Gaps = 3/123 (2%)

Query: 13  IVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVM--HPEGNGRSG-FLIHGERQKDKLV 69
           +VRV+AVVM RDDSSGGW P  GGG+S+V VC+V    PEG  R G ++IHGER +D+  
Sbjct: 1   MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKT 60

Query: 70  VLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTS 129
            LEC ++  LVY K NP FHHW + + KFGLTFQSPA+A  F + +  A+  L  GS T 
Sbjct: 61  TLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTP 120

Query: 130 SST 132
           SS+
Sbjct: 121 SSS 123


>gi|27501452 sprouty homolog 3 [Homo sapiens]
          Length = 288

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 25/145 (17%)

Query: 280 PKGRGGSVIKTQPSRGKSRRR----KEDGERSRCVYCRDMFNHEENRRGHC--------- 326
           P   G S+I+TQP  G   +     K + E+S       +F  EE  R  C         
Sbjct: 105 PSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPL 164

Query: 327 -------QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFC-LR 377
                  Q    S  + +   +C+ C   + YHC +D E +  D PCSC  S    C +R
Sbjct: 165 PSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS---CFVR 221

Query: 378 WMALIALSFLAPCMCCYLPLRACYH 402
           W A+  +S   PC+CCYLP R C H
Sbjct: 222 WAAMSLISLFLPCLCCYLPTRGCLH 246


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 6/111 (5%)

Query: 13  IVRVKAVVMTRDDSSGGWFPQEGG-GISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVL 71
           I + +A VM  DD++  W P  G  G SRV    + H  GN    F + G + +D  VV+
Sbjct: 6   ICQARAAVMVYDDANKKWVPAGGSTGFSRV---HIYHHTGNNT--FRVVGRKIQDHQVVI 60

Query: 72  ECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 122
            C + K L Y +A  TFH W+   + +GL F S  DA  F   +  A+E L
Sbjct: 61  NCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 111


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 6/111 (5%)

Query: 13  IVRVKAVVMTRDDSSGGWFPQEGG-GISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVL 71
           I + +A VM  DD++  W P  G  G SRV    + H  GN    F + G + +D  VV+
Sbjct: 6   ICQARAAVMVYDDANKKWVPAGGSTGFSRV---HIYHHTGNNT--FRVVGRKIQDHQVVI 60

Query: 72  ECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 122
            C + K L Y +A  TFH W+   + +GL F S  DA  F   +  A+E L
Sbjct: 61  NCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVL 111


>gi|5032115 sprouty 2 [Homo sapiens]
          Length = 315

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 6/80 (7%)

Query: 332 SVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFCLRWMALIALSFLAPC 390
           S +  I   +C+ C   + YHC +D E +  D PCSC  S    C RW A+  +S   PC
Sbjct: 208 SAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSC--SQSHCCTRWSAMGVMSLFLPC 265

Query: 391 MCCYLPLRACYHCGVMCRCC 410
           + CYLP + C     +C+ C
Sbjct: 266 LWCYLPAKGCLK---LCQGC 282


>gi|7706687 Enah/Vasp-like [Homo sapiens]
          Length = 418

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 48/179 (26%), Positives = 76/179 (42%), Gaps = 24/179 (13%)

Query: 13  IVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVV 70
           I + +A VM  DD+S  W P + G  G SR+ +           + F + G + +D+ VV
Sbjct: 8   ICQARASVMVYDDTSKKWVPIKPGQQGFSRINIY-----HNTASNTFRVVGVKLQDQQVV 62

Query: 71  LECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKA--IEDLIEGSTT 128
           +   + K L Y +A PTFH W+   + +GL F S  +A  F   +  A  I +  EG  +
Sbjct: 63  INYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPS 122

Query: 129 SSSTIHN-----EAELGDDDVFTTATDSSSNSSQKRE----------QPTRTISSPTSC 172
           S   + N     E ++    V          S ++R            P+   S+P SC
Sbjct: 123 SQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAASAPVSC 181


>gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo
           sapiens]
          Length = 319

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 7/81 (8%)

Query: 332 SVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTD-PCSCDTSDEKFCLRWMALIALSFLAP 389
           S  + +   +CM     + YHC +D EGD Y+D PCSC  S    C R++ + A+S   P
Sbjct: 211 SAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSC--SQSHCCSRYLCMGAMSLFLP 268

Query: 390 CMCCYLPLRACYHCGVMCRCC 410
           C+ CY P + C     +CR C
Sbjct: 269 CLLCYPPAKGCLK---LCRRC 286


>gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo
           sapiens]
          Length = 319

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 7/81 (8%)

Query: 332 SVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTD-PCSCDTSDEKFCLRWMALIALSFLAP 389
           S  + +   +CM     + YHC +D EGD Y+D PCSC  S    C R++ + A+S   P
Sbjct: 211 SAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSC--SQSHCCSRYLCMGAMSLFLP 268

Query: 390 CMCCYLPLRACYHCGVMCRCC 410
           C+ CY P + C     +CR C
Sbjct: 269 CLLCYPPAKGCLK---LCRRC 286


>gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]
          Length = 299

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 327 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 384
           Q+   S +T +   +CM     + YHC + D EG   D PCSC  S+   C RW  + AL
Sbjct: 184 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 241

Query: 385 SFLAPCMCCYLPLRAC 400
           S + PC+ CYLP   C
Sbjct: 242 SVVLPCLLCYLPATGC 257


>gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]
          Length = 322

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 327 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 384
           Q+   S +T +   +CM     + YHC + D EG   D PCSC  S+   C RW  + AL
Sbjct: 207 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 264

Query: 385 SFLAPCMCCYLPLRAC 400
           S + PC+ CYLP   C
Sbjct: 265 SVVLPCLLCYLPATGC 280


>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
          Length = 380

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 8/119 (6%)

Query: 10  DSYIVRVKAVVMTRDDSSGGWFPQEGG--GISRVGVCKVMHPEGNGRSGFLIHGER-QKD 66
           ++ I   +A VM  DD +  W P   G    SRV +    +P  N    F + G + Q D
Sbjct: 3   ETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYH--NPTANS---FRVVGRKMQPD 57

Query: 67  KLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEG 125
           + VV+ C + + + Y +A P FH W+   + +GL F S  DA  F  G+  A+E L  G
Sbjct: 58  QQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGG 116


>gi|14210518 PAR-6 gamma protein [Homo sapiens]
          Length = 376

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 8/140 (5%)

Query: 96  RKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEA-ELGDDDVFTTATDSSSN 154
           R+F L    P     F + V           T   + +H +   + +DD F  A  S++ 
Sbjct: 30  RRFSLDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANP 89

Query: 155 SS----QKREQPTR-TISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMPRPYRQVSFPD 209
                 QKRE+  R ++ + + C  RR   LG L D  P    HLD  +PR +R VS   
Sbjct: 90  LLRVFIQKREEAERGSLGAGSLCRRRR--ALGALRDEGPRRRAHLDIGLPRDFRPVSSII 147

Query: 210 DDEEIVRINPREKIWMTGYE 229
           D + +   + R ++   G E
Sbjct: 148 DVDLVPETHRRVRLHRHGCE 167


>gi|7662022 lipin 2 [Homo sapiens]
          Length = 896

 Score = 32.7 bits (73), Expect = 0.63
 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 26/130 (20%)

Query: 101 TFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELG---DDDVFTTATDSSSNSSQ 157
           T  +P+  +   R  +K  +D  +    +S+   +  ++G   DDD    A   SSN+S 
Sbjct: 145 TIFTPSSVKKKKRRRKKYKQDSKKEEQAASAAAEDTCDVGVSSDDDKGAQAARGSSNASL 204

Query: 158 KREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLD----QPMPRPYRQVSFPDDDEE 213
           K E+          C+   ++  G        DHY L      P+   Y Q + P  D E
Sbjct: 205 KEEE----------CKEPLLFHSG--------DHYPLSDGDWSPLETTYPQTACPKSDSE 246

Query: 214 IVRINPREKI 223
           +  + P E +
Sbjct: 247 L-EVKPAESL 255


>gi|4757886 pituitary tumor-transforming gene 1 protein-interacting
           protein precursor [Homo sapiens]
          Length = 180

 Score = 32.3 bits (72), Expect = 0.82
 Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 6/88 (6%)

Query: 327 QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCS-CDTSDEKFCLRWMALIALS 385
           Q+   +   C++ VSC+WC  +    C+  P      P S C  S  ++ + W+   AL 
Sbjct: 42  QNTNKTCEECLKNVSCLWCNTNKA--CLDYPVTSVLPPASLCKLSSARWGVCWVNFEALI 99

Query: 386 FLAPCMCCYLPLRACYHCGVMCRCCGGK 413
                +   L L     C   C CC  K
Sbjct: 100 ITMSVVGGTLLLGIAICC---CCCCRRK 124


>gi|239750462 PREDICTED: similar to hCG2033802 [Homo sapiens]
          Length = 188

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 16/104 (15%)

Query: 326 CQDAPDSVRTCIRRVSCMWCADSM--LYHCMSDPEGDYT-------DPCSCDTSDEKFCL 376
           C D    + T ++ ++C  CA +   +  CM      YT       D C C  +    C+
Sbjct: 20  CMDVCVCLYTMLKEITCDVCARACACVCECMDVCMCLYTMLKDVTCDVCMCTCTCMCVCV 79

Query: 377 R-WMALIALSFLAPCMCCYLP-LRACYH-----CGVMCRCCGGK 413
             WM +   + L    C      RAC       C  +C CCGG+
Sbjct: 80  SAWMCVCMYTMLKEVTCDVCARARACVRECMDVCAPVCVCCGGQ 123


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2709 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2767


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 344  WCADSMLYHCMSDPEGD--YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRAC 400
            W AD   +HC S P G      P SC   +E  C +    +  S    C  C    R+C
Sbjct: 2781 WIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSC 2839


>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
          Length = 725

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 239 KYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSR 298
           K+   SE   +    F++ E P    + P   +S        +G  G+    +P +  S+
Sbjct: 470 KHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAA-GLEPRKLSSK 528

Query: 299 RRKEDGERSRCVYCRDMFNHEENRRGHCQ 327
            R+ D E+  C  C + FN    RR HC+
Sbjct: 529 TRR-DKEKQSCKSCGETFNSITKRRHHCK 556


>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
          Length = 725

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 239 KYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSR 298
           K+   SE   +    F++ E P    + P   +S        +G  G+    +P +  S+
Sbjct: 470 KHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAA-GLEPRKLSSK 528

Query: 299 RRKEDGERSRCVYCRDMFNHEENRRGHCQ 327
            R+ D E+  C  C + FN    RR HC+
Sbjct: 529 TRR-DKEKQSCKSCGETFNSITKRRHHCK 556


>gi|148806908 fibronectin type III domain containing 1 [Homo
           sapiens]
          Length = 1894

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 19/85 (22%)

Query: 237 RGKYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGED----------------- 279
           RG    PS    S+    A   VP H  ++P + S   G  ED                 
Sbjct: 839 RGPRLQPSSSPQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSSS 898

Query: 280 --PKGRGGSVIKTQPSRGKSRRRKE 302
             P  RG   ++  P RG S  RKE
Sbjct: 899 RQPISRGWEDLRRSPQRGASLHRKE 923


>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
           sapiens]
          Length = 908

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 124 EGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGH 182
           + S +SSS+  + +E    D  + ++DSSS SS + E  + +ISS +S     +   GH
Sbjct: 665 KSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSE-ESDSSSISSHSSASANDVRKKGH 722


>gi|15042949 PR domain containing 12 [Homo sapiens]
          Length = 367

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 17/40 (42%), Positives = 18/40 (45%), Gaps = 4/40 (10%)

Query: 306 RSRCVYCRDMFNHEENRRGHCQ----DAPDSVRTCIRRVS 341
           R RCV C   FN   N R H +    D P   R C RR S
Sbjct: 242 RMRCVICHRGFNSRSNLRSHMRIHTLDKPFVCRFCNRRFS 281


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,804,342
Number of Sequences: 37866
Number of extensions: 958347
Number of successful extensions: 2683
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 2610
Number of HSP's gapped (non-prelim): 80
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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