Guide to the Human Genome
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Search of human proteins with 189217874

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189217874 neurensin 1 [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189217874 neurensin 1 [Homo sapiens]                               394   e-110
gi|13376447 neurensin 2 [Homo sapiens]                                108   4e-24
gi|23308545 transmembrane protein 74 [Homo sapiens]                    40   0.002
gi|8922927 hypothetical protein LOC55321 [Homo sapiens]                30   1.00 
gi|55743118 RAB3 GTPase-activating protein [Homo sapiens]              29   2.2  
gi|4758406 fucosyltransferase 7 [Homo sapiens]                         28   3.8  
gi|187423910 solute carrier family 7, member 9 [Homo sapiens]          28   4.9  
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]            28   4.9  
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    28   4.9  
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    28   4.9  
gi|22748623 Fanconi anemia-associated protein, 24 kDa [Homo sapi...    28   4.9  
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...    27   8.4  
gi|24308382 leukocyte receptor cluster member 8 [Homo sapiens]         27   8.4  

>gi|189217874 neurensin 1 [Homo sapiens]
          Length = 195

 Score =  394 bits (1013), Expect = e-110
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSV 60
           MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSV
Sbjct: 1   MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSV 60

Query: 61  FWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGA 120
           FWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGA
Sbjct: 61  FWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGA 120

Query: 121 VLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP 180
           VLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP
Sbjct: 121 VLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP 180

Query: 181 VTLSRVQNVQPLLAT 195
           VTLSRVQNVQPLLAT
Sbjct: 181 VTLSRVQNVQPLLAT 195


>gi|13376447 neurensin 2 [Homo sapiens]
          Length = 204

 Score =  108 bits (269), Expect = 4e-24
 Identities = 54/139 (38%), Positives = 78/139 (56%), Gaps = 3/139 (2%)

Query: 1   MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNR-WSS 59
           M SC+  C   +  +  +G +  YGVRSYLH FYEDC  +    + +      P R W S
Sbjct: 2   MPSCNRSCSCSRGPSVEDGKW--YGVRSYLHLFYEDCAGTALSDDPEGPPVLCPRRPWPS 59

Query: 60  VFWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAG 119
           + WK+ L SGT+ ++LG+  L  G+ VPPK+E  GE +F+V+D  A  +N AL   +LAG
Sbjct: 60  LCWKISLSSGTLLLLLGVAALTTGYAVPPKLEGIGEGEFLVLDQRAADYNQALGTCRLAG 119

Query: 120 AVLFCIGGTSMAGCLLMSV 138
             L    G  +A CL  ++
Sbjct: 120 TALCVAAGVLLAICLFWAM 138


>gi|23308545 transmembrane protein 74 [Homo sapiens]
          Length = 305

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 23/127 (18%), Positives = 60/127 (47%), Gaps = 6/127 (4%)

Query: 31  HQFYEDCTASIWEYEDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPKI 90
           +++ ++   S+   E+D     + +   S+ +  G IS  +F++ G+ ++ + ++VP ++
Sbjct: 145 NEWSQEAAISLISEEEDDTSSEATSSGKSIDY--GFISAILFLVTGILLVIISYIVPREV 202

Query: 91  ----EAFGEADFVVVDTHAVQFNSALDMYKLAGAVLFCIGGTSMAGCLLMSVFVKSYSKE 146
                     +   ++  + +  + LD   +AG  L  +GG  ++  L+MS++     + 
Sbjct: 203 TVDPNTVAAREMERLEKESARLGAHLDRCVIAGLCLLTLGGVILSCLLMMSMWKGELYRR 262

Query: 147 EKFLQQK 153
            +F   K
Sbjct: 263 NRFASSK 269


>gi|8922927 hypothetical protein LOC55321 [Homo sapiens]
          Length = 256

 Score = 30.4 bits (67), Expect = 1.00
 Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 65  GLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVV------VDTHAVQFNSALDMYKLA 118
           G +S  VF++ G+ ++   + +P   EA    D V       ++ +  +  S LD   +A
Sbjct: 122 GFVSALVFLVSGILLVVTAYAIPR--EARVNPDTVTAREMERLEMYYARLGSHLDRCIIA 179

Query: 119 GAVLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQK 153
           G  L  +GG  ++  L++S+      +   F+  K
Sbjct: 180 GLGLLTVGGMLLSVLLMVSLCKGELYRRRTFVPGK 214


>gi|55743118 RAB3 GTPase-activating protein [Homo sapiens]
          Length = 981

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 133 CLLMSVFVKSYSKEEKFLQQ--KFKERIADIKAHTQPVTKAPGPGETKIPVTLSRVQNVQ 190
           C++ +  +K   KEE+ L+     K+ I  I +H+  V   P P + K+   + ++ NV+
Sbjct: 783 CVIHAAVLKV--KEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVE 840

Query: 191 PLLA 194
            L+A
Sbjct: 841 ALIA 844


>gi|4758406 fucosyltransferase 7 [Homo sapiens]
          Length = 342

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 15/56 (26%)

Query: 61  FWKVGLISGTVFVILGLTVLAVGFLVPPK--IEAFGEADFVVVDTHAVQFNSALDM 114
           FW+  L++GTV V+LG          PP+   EAF  AD  V   H   F SA ++
Sbjct: 241 FWRNALVAGTVPVVLG----------PPRATYEAFVPADAFV---HVDDFGSAREL 283


>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 2/45 (4%)

Query: 45 EDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPK 89
          ED+  IQ    + +S+  ++GLISG + +I+G T++  G  V PK
Sbjct: 11 EDEKSIQSQEPKTTSLQKELGLISG-ISIIVG-TIIGSGIFVSPK 53


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 2/45 (4%)

Query: 45 EDDFQIQRSPNRWSSVFWKVGLISGTVFVILGLTVLAVGFLVPPK 89
          ED+  IQ    + +S+  ++GLISG + +I+G T++  G  V PK
Sbjct: 11 EDEKSIQSQEPKTTSLQKELGLISG-ISIIVG-TIIGSGIFVSPK 53


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 142 SYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP 180
           S S +E  ++ K  E+I  ++A + P    PG G T  P
Sbjct: 204 SSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP 242


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 142 SYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP 180
           S S +E  ++ K  E+I  ++A + P    PG G T  P
Sbjct: 204 SSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP 242


>gi|22748623 Fanconi anemia-associated protein, 24 kDa [Homo
           sapiens]
          Length = 215

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 7/90 (7%)

Query: 105 AVQFNSALDMYKLAGAVLFCIGGTSMAGCLLMSVFVKSYSKE--EKFLQQKFKERIADIK 162
           A+Q  + LD+    G VL  +     A CL++ + V+  +KE  +  L  K +  +    
Sbjct: 103 ALQKFTVLDL----GMVLLPVASQMEASCLVIQL-VQEQTKEPSKNPLLGKKRALLLSEP 157

Query: 163 AHTQPVTKAPGPGETKIPVTLSRVQNVQPL 192
           +  + V + PG G+ K P+ L +  ++Q L
Sbjct: 158 SLLRTVQQIPGVGKVKAPLLLQKFPSIQQL 187


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 13/30 (43%), Positives = 17/30 (56%)

Query: 165  TQPVTKAPGPGETKIPVTLSRVQNVQPLLA 194
            T PV +  GPGE + P  L+R Q   P L+
Sbjct: 2212 TPPVVRPAGPGEAQEPEELARRQRRHPELS 2241


>gi|24308382 leukocyte receptor cluster member 8 [Homo sapiens]
          Length = 800

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 14/40 (35%), Positives = 23/40 (57%)

Query: 145 KEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIPVTLS 184
           + EK L++  + R+ D  A+T   ++ P PG T+ PV  S
Sbjct: 312 RTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAES 351


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,395,679
Number of Sequences: 37866
Number of extensions: 283359
Number of successful extensions: 863
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 855
Number of HSP's gapped (non-prelim): 13
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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