Search of human proteins with 189217845

Search of human proteins with 189217845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189217845 spastic paraplegia 21 isoform a [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189217845 spastic paraplegia 21 isoform a [Homo sapiens]           632   0.0  
gi|7706174 spastic paraplegia 21 isoform a [Homo sapiens]             632   0.0  
gi|189217847 spastic paraplegia 21 isoform b [Homo sapiens]           556   e-159
gi|31542303 abhydrolase domain containing 5 [Homo sapiens]             32   0.71 
gi|150010540 FERM domain containing 4B [Homo sapiens]                  31   1.6  
gi|49355818 plexin A1 [Homo sapiens]                                   30   3.5  
gi|32698730 nuclear fragile X mental retardation protein interac...    30   3.5  
gi|94721313 mesoderm induction early response 1, family member 3...    29   4.6  
gi|113722116 plexin A2 [Homo sapiens]                                  29   6.0  

>gi|189217845 spastic paraplegia 21 isoform a [Homo sapiens]
          Length = 308

 Score =  632 bits (1629), Expect = 0.0
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120
           RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE
Sbjct: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120

Query: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180
           YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA
Sbjct: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180

Query: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240
           IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK
Sbjct: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240

Query: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300
           LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS
Sbjct: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300

Query: 301 LGISQEEQ 308
           LGISQEEQ
Sbjct: 301 LGISQEEQ 308


>gi|7706174 spastic paraplegia 21 isoform a [Homo sapiens]
          Length = 308

 Score =  632 bits (1629), Expect = 0.0
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120
           RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE
Sbjct: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120

Query: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180
           YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA
Sbjct: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180

Query: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240
           IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK
Sbjct: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240

Query: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300
           LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS
Sbjct: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300

Query: 301 LGISQEEQ 308
           LGISQEEQ
Sbjct: 301 LGISQEEQ 308


>gi|189217847 spastic paraplegia 21 isoform b [Homo sapiens]
          Length = 281

 Score =  556 bits (1434), Expect = e-159
 Identities = 281/308 (91%), Positives = 281/308 (91%), Gaps = 27/308 (8%)

Query: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60
           MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF
Sbjct: 1   MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFF 60

Query: 61  RQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAE 120
           RQILALTGWGYRVIA                           VHLFGASLGGFLAQKFAE
Sbjct: 61  RQILALTGWGYRVIA---------------------------VHLFGASLGGFLAQKFAE 93

Query: 121 YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 180
           YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA
Sbjct: 94  YTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADA 153

Query: 181 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 240
           IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK
Sbjct: 154 IDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYK 213

Query: 241 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 300
           LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS
Sbjct: 214 LYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGS 273

Query: 301 LGISQEEQ 308
           LGISQEEQ
Sbjct: 274 LGISQEEQ 281


>gi|31542303 abhydrolase domain containing 5 [Homo sapiens]
          Length = 349

 Score = 32.0 bits (71), Expect = 0.71
 Identities = 40/126 (31%), Positives = 52/126 (41%), Gaps = 32/126 (25%)

Query: 29  SKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVY-WDHLEF 87
           +KIW+L  +   S + PL+ L    G         L L    +  +    PVY +D L F
Sbjct: 61  NKIWTLKFSHNISNKTPLVLLHGFGGG--------LGLWALNFGDLCTNRPVYAFDLLGF 112

Query: 88  CDGFRKLLDH-------------------LQLDKVHLFGASLGGFLAQKFAEYTHKSP-R 127
               R   D                    L LDK+ L G +LGGFLA   A Y+ K P R
Sbjct: 113 GRSSRPRFDSDAEEVENQFVESIEEWRCALGLDKMILLGHNLGGFLA---AAYSLKYPSR 169

Query: 128 VHSLIL 133
           V+ LIL
Sbjct: 170 VNHLIL 175


>gi|150010540 FERM domain containing 4B [Homo sapiens]
          Length = 1034

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 17/123 (13%)

Query: 92  RKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTAN- 150
           RKL    QL+ ++        F  +KFA   H   R+   +   +F  + +F QTW AN 
Sbjct: 291 RKLFQWKQLENLY--------FREKKFAVEVHDPRRIS--VSRRTFGQSGLFVQTWYANS 340

Query: 151 ----SFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQN 206
               S W+M A    +  L    S    P  A ++D +   L   G    +  +TL  ++
Sbjct: 341 SLIKSIWVM-AISQHQFYLDRKQSKAKIP-SARSLDEIAMDLTETGTQRASKLVTLEAKS 398

Query: 207 SYV 209
            ++
Sbjct: 399 QFI 401


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 156  PAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIR 215
            P FML   +      GP+D +  +A  + +   + + Q      LTLNC N   E     
Sbjct: 1437 PLFMLYCAIKQQMEKGPIDAITGEA-RYSLSEDKLIRQQIDYKTLTLNCVNP--ENENAP 1493

Query: 216  DIPVTIMDVFDQSALSTEAKEEMYKLYPNARR 247
            ++PV  +D    +    +  +  YK  P ++R
Sbjct: 1494 EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQR 1525


>gi|32698730 nuclear fragile X mental retardation protein
           interacting protein 2 [Homo sapiens]
          Length = 695

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 115 AQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWL--MPAFMLKKIVLGNFSSGP 172
           A K  E  +K+ +  S+   +S S +S   +T T +S  L  +P   LK +   NFS+GP
Sbjct: 359 ASKVKENLNKTIQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGP 418

Query: 173 V 173
           V
Sbjct: 419 V 419


>gi|94721313 mesoderm induction early response 1, family member 3
           [Homo sapiens]
          Length = 549

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 6/57 (10%)

Query: 175 PMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALS 231
           P + D +D +VD  E+LG +  AS LT N       P  I D  + I++ F  S L+
Sbjct: 347 PGVTDYMDRLVDETEALGGTVNASALTSN------RPEPIPDQQLNILNSFTASDLT 397


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 156  PAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIR 215
            P FML   +      GP+D +  +A  + +   + + Q      L LNC N   +     
Sbjct: 1457 PLFMLYCAIKQQMEKGPIDAITGEA-RYSLSEDKLIRQQIEYKTLILNCVNP--DNENSP 1513

Query: 216  DIPVTIMDVFDQSALSTEAKEEMYKLYPNARR 247
            +IPV +++    + +  +  + +YK  P ++R
Sbjct: 1514 EIPVKVLNCDTITQVKEKILDAVYKNVPYSQR 1545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,497,840
Number of Sequences: 37866
Number of extensions: 464508
Number of successful extensions: 800
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 796
Number of HSP's gapped (non-prelim): 9
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.