Search of human proteins with 188536094

Search of human proteins with 188536094

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188536094 deafness, autosomal dominant 5 protein isoform b
[Homo sapiens]
         (332 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758154 deafness, autosomal dominant 5 protein isoform a [Hom...   655   0.0  
gi|188536094 deafness, autosomal dominant 5 protein isoform b [H...   655   0.0  
gi|188536092 deafness, autosomal dominant 5 protein isoform a [H...   655   0.0  
gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]           51   2e-06
gi|57222563 colonic and hepatic tumor over-expressed protein iso...    31   1.3  
gi|57164942 colonic and hepatic tumor over-expressed protein iso...    31   1.3  

>gi|4758154 deafness, autosomal dominant 5 protein isoform a [Homo
           sapiens]
          Length = 496

 Score =  655 bits (1689), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 60
           MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL
Sbjct: 165 MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 224

Query: 61  YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 120
           YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV
Sbjct: 225 YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 284

Query: 121 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 180
           LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV
Sbjct: 285 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 344

Query: 181 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 240
           LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL
Sbjct: 345 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 404

Query: 241 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 300
           GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS
Sbjct: 405 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 464

Query: 301 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 332
           SVKAVILKDSKVFPLLLCITLNGLCALGREHS
Sbjct: 465 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 496


>gi|188536094 deafness, autosomal dominant 5 protein isoform b [Homo
           sapiens]
          Length = 332

 Score =  655 bits (1689), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 60
           MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL
Sbjct: 1   MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 60

Query: 61  YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 120
           YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV
Sbjct: 61  YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 120

Query: 121 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 180
           LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV
Sbjct: 121 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 180

Query: 181 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 240
           LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL
Sbjct: 181 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 240

Query: 241 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 300
           GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS
Sbjct: 241 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 300

Query: 301 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 332
           SVKAVILKDSKVFPLLLCITLNGLCALGREHS
Sbjct: 301 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 332


>gi|188536092 deafness, autosomal dominant 5 protein isoform a [Homo
           sapiens]
          Length = 496

 Score =  655 bits (1689), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 60
           MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL
Sbjct: 165 MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIEL 224

Query: 61  YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 120
           YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV
Sbjct: 225 YVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSV 284

Query: 121 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 180
           LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV
Sbjct: 285 LKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAV 344

Query: 181 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 240
           LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL
Sbjct: 345 LGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALL 404

Query: 241 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 300
           GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS
Sbjct: 405 GTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKS 464

Query: 301 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 332
           SVKAVILKDSKVFPLLLCITLNGLCALGREHS
Sbjct: 465 SVKAVILKDSKVFPLLLCITLNGLCALGREHS 496


>gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]
          Length = 352

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 3/83 (3%)

Query: 4   CVISEHMQVEEKCGGIV--GIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELY 61
           CV+ E ++   +C   V  GI+ + ++    ++ N  K  +  +  PA TTIA+ V EL+
Sbjct: 157 CVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQN-PKGRDKAIVFPAHTTIAFSVFELF 215

Query: 62  VKLDGQFEFCLLRGKQGGFENKK 84
           + LDG F+ C+    +GGFE ++
Sbjct: 216 IYLDGAFDLCVTSVSKGGFEREE 238


>gi|57222563 colonic and hepatic tumor over-expressed protein isoform
            b [Homo sapiens]
          Length = 1972

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 15/42 (35%), Positives = 23/42 (54%)

Query: 137  ELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTV 178
            E+PE  Q  L DIF+ VL  +  +  + P  DD+ S  + T+
Sbjct: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTI 1542


>gi|57164942 colonic and hepatic tumor over-expressed protein isoform
            a [Homo sapiens]
          Length = 2032

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 15/42 (35%), Positives = 23/42 (54%)

Query: 137  ELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTV 178
            E+PE  Q  L DIF+ VL  +  +  + P  DD+ S  + T+
Sbjct: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTI 1542


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,268,321
Number of Sequences: 37866
Number of extensions: 520613
Number of successful extensions: 1077
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1069
Number of HSP's gapped (non-prelim): 8
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.