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Search of human proteins with 188536067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo
sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 918 0.0
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 365 e-101
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 354 1e-97
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 318 6e-87
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 316 2e-86
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 309 3e-84
gi|27436871 carboxypeptidase O [Homo sapiens] 304 1e-82
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 296 3e-80
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 296 3e-80
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 294 1e-79
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 293 2e-79
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 226 2e-59
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 205 6e-53
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 54 2e-07
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 54 2e-07
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 54 2e-07
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 50 4e-06
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 49 7e-06
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 46 8e-05
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 45 1e-04
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 45 1e-04
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 45 1e-04
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 41 0.002
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 37 0.035
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 33 0.51
gi|120444924 ATP/GTP binding protein-like 1 [Homo sapiens] 32 1.1
gi|45237195 Janus kinase and microtubule interacting protein 2 [... 31 2.5
gi|239752401 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|239754336 PREDICTED: hypothetical protein [Homo sapiens] 30 4.3
gi|239748878 PREDICTED: similar to serine/threonine-protein kina... 30 4.3
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 918 bits (2373), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS 60
MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS
Sbjct: 1 MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKIS 60
Query: 61 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS 120
YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS
Sbjct: 61 YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGS 120
Query: 121 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLG 180
SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLG
Sbjct: 121 SLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLG 180
Query: 181 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV 240
RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV
Sbjct: 181 RRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNV 240
Query: 241 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE 300
DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE
Sbjct: 241 DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESE 300
Query: 301 PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS 360
PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS
Sbjct: 301 PEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQS 360
Query: 361 VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE 420
VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE
Sbjct: 361 VYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE 420
Query: 421 TMLAVKNITMHLLKKCP 437
TMLAVKNITMHLLKKCP
Sbjct: 421 TMLAVKNITMHLLKKCP 437
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 365 bits (937), Expect = e-101
Identities = 171/418 (40%), Positives = 261/418 (62%), Gaps = 5/418 (1%)
Query: 17 LCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYV 76
L L L + +H + G+KV R + E +++++ ++D W+P S++ +
Sbjct: 2 LALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQI 61
Query: 77 SEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNY 136
+ D + + + L++ +QYKVLI +L+ +E +R +G++Y
Sbjct: 62 KPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFD-----SRVRATGHSY 116
Query: 137 EVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIH 196
E Y+ E I+ W + + LI IG ++EGR++++LK+G+ + K A+++DCG H
Sbjct: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
Query: 197 AREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKT 256
AREWI PAFCQWFV+EA+ TY + + ++L+ L FY++PV N+DGY ++WT RFWRKT
Sbjct: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
Query: 257 RSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKH 316
RS ++ C G D NRN+ WC+ GAS +PCD+TYCGP ESE E KA+A+F+R
Sbjct: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
Query: 317 IRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLY 376
I+AYL+ H+Y+QM++YPYSY Y N + + A V L S++G +Y YGP +TT+Y
Sbjct: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
Query: 377 VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434
++G S DWAY GI Y+F FELRDTG +GFLLPE I+ TC ET LA+K + ++L+
Sbjct: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 354 bits (908), Expect = 1e-97
Identities = 170/399 (42%), Positives = 244/399 (61%), Gaps = 4/399 (1%)
Query: 36 RYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALL 95
R+ +KV R P+ E++A +K ++ ++D W P + +V+ + D + + S+A+
Sbjct: 20 RFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQ 79
Query: 96 AFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKT 155
+ L + + Y++LI DLQ+ +EK + R ++Y Y++ E+I W +
Sbjct: 80 SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGR----HSYAKYNNWEKIVAWTEKMMDK 135
Query: 156 HSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
+ ++ IG + E L++LK+G ++ ++A++ DCGIHAREW+ PAFCQWFV +A
Sbjct: 136 YPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATK 195
Query: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
TY + M K+L+ + FYI+PVFNVDGY +SWT +R WRK RS+N +C G D NRN+
Sbjct: 196 TYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFN 255
Query: 276 VKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYS 335
W + PC D Y G PESE E KAV NF+R H I+ Y++FH+Y+QMLL+PY
Sbjct: 256 ASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYG 315
Query: 336 YKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAF 395
Y PN + A + L + Y RY YGP +T+Y SGSS+DWAY GI + F
Sbjct: 316 YTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTF 375
Query: 396 AFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434
AFELRD G FGFLLPE IKPTC ETMLAVK I ++LK
Sbjct: 376 AFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 318 bits (815), Expect = 6e-87
Identities = 161/401 (40%), Positives = 232/401 (57%), Gaps = 5/401 (1%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLA 96
+ +V+ +P+T + L+ ++ ++ LWQP + + + + + + A
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82
Query: 97 FLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTH 156
L + I VL+ D++ +++ S T R S S YE YHSL EI +W+ + + H
Sbjct: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS--YYEQYHSLNEIYSWIEFITERH 140
Query: 157 SGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 141 PDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQ 200
Query: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
Y +L + FY+MPV NVDGY +SW +R WRK RS + C G D NRN+
Sbjct: 201 FYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFA 260
Query: 276 VK-WCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
K WC+EGAS C +TYCG +PESEPEVKAVA+FLR++ I+AY+S H+Y+Q +++PY
Sbjct: 261 SKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY 320
Query: 335 SYKYATIPNFRCVESAAYKAVNALQSV-YGVRYRYGPASTTLYVSSGSSMDWAYKNGIPY 393
SY + + + A +AV A++ RY +G S TLY++ G DW Y GI Y
Sbjct: 321 SYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKY 380
Query: 394 AFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434
+F ELRDTG +GFLLPE IKPTC E AV I H+++
Sbjct: 381 SFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 316 bits (810), Expect = 2e-86
Identities = 163/406 (40%), Positives = 243/406 (59%), Gaps = 10/406 (2%)
Query: 31 HLYN-NRYAGDKVIRFIPKTEEEAYALKKISYQ--LKVDLWQPSSISYVSEGTVTDVHIP 87
H+Y + GD+V+ +P EE+ L ++ Q L++D W+ S + G V +P
Sbjct: 15 HIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWK----SPTTPGETAHVRVP 70
Query: 88 QNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSG-YNYEVYHSLEEIQ 146
+A+ FL+ I Y ++IED+Q L+K + RR SG +N+ YH+LEEI
Sbjct: 71 FVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEIS 130
Query: 147 NWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFC 206
M +L H GL+ +IG S+E R + +LK K A+W+D GIHAREW+ A
Sbjct: 131 QEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-KPAIWLDAGIHAREWVTQATA 189
Query: 207 QWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCR 266
W + + Y DP++ +L+ L +++PV N DGY FS T +R WRKTRS+ S C
Sbjct: 190 LWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCV 249
Query: 267 GVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAY 326
GVD NRNW + GAS +PC D+Y GP SE EVK++ +F++ H K ++A+++ H+Y
Sbjct: 250 GVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK-VKAFITLHSY 308
Query: 327 AQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWA 386
+Q+L++PY YK + +F + A KA +L+S++G +Y+ GP + +Y +SG S+DW+
Sbjct: 309 SQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWS 368
Query: 387 YKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 432
Y GI Y+FAFELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 369 YDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 309 bits (792), Expect = 3e-84
Identities = 163/410 (39%), Positives = 235/410 (57%), Gaps = 10/410 (2%)
Query: 28 GHSHLYNNRYAGDKVIRFIPKTEEEAYALKKI--SYQLKVDLWQPSSISYVSEGTVTDVH 85
G S ++ GD+V+R + +E L ++ S LK++ W+ S S DV
Sbjct: 12 GSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPS----SFNRPVDVL 67
Query: 86 IPQNGSRALLAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLE 143
+P +A +FL+ ++Y V IEDLQ L E H + RS + +NY YHSLE
Sbjct: 68 VPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLE 127
Query: 144 EIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKR-AVWIDCGIHAREWIG 202
I + M ++ L IG S+E R +++LK ++R AVW++ GIH+REWI
Sbjct: 128 AIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWIS 187
Query: 203 PAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSR 262
A W ++ + Y+ DPA+ +L + +++PV N DGY ++ T +R WRKTRSRN
Sbjct: 188 QATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPG 247
Query: 263 FRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLS 322
C G D NRNW + +GAS +PC + Y GP SE EVK+V +F++KH + + ++
Sbjct: 248 SSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKH-GNFKGFID 306
Query: 323 FHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSS 382
H+Y+Q+L+YPY Y P+ ++ A A AL SV G Y+ GP TT+Y +SGSS
Sbjct: 307 LHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSS 366
Query: 383 MDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 432
+DWAY NGI +AF FELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 367 IDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHV 416
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 304 bits (778), Expect = 1e-82
Identities = 139/300 (46%), Positives = 196/300 (65%), Gaps = 1/300 (0%)
Query: 130 SLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRS-RLKRA 188
SL Y+Y +YH + EI WM +++ + ++ +G +YE ++ LK+ + S K+
Sbjct: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
Query: 189 VWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWT 248
+W+DCGIHAREWI PAFCQWFVKE L +K + ++RK+L +L FY++PV N+DGY ++WT
Sbjct: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
Query: 249 NDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVAN 308
DR WRK+RS ++ C G D NRN+ WC GAS + D T+CG P SEPE KAVA+
Sbjct: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
Query: 309 FLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRY 368
F+ + I +L+ H+Y Q++L PY Y N + KA NAL++ YG YR
Sbjct: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
Query: 369 GPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNI 428
G ++ LY SSGSS DWA GIP+++ FELRD+G +GF+LPE I+PTC ETM AV ++
Sbjct: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 296 bits (757), Expect = 3e-80
Identities = 154/401 (38%), Positives = 233/401 (58%), Gaps = 9/401 (2%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94
+ GD+V+R + K E++ L + KVD W+ + D+ +P + + +
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RPSLPVDMRVPFSELKDI 92
Query: 95 LAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHL 152
A+L+ + Y ++I+D+Q L E+ + ++R RS + ++Y YH+LEEI +W+ +
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212
HS ++ IG S+E +S+ +LK A+WID GIH+REWI A W +
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANK 212
Query: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272
+ Y D + +LN + +I V N DG+ F+ + +R WRK +S C GVD NR
Sbjct: 213 IVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNR 272
Query: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332
NWK + G++ +PC +TY GP P+SEPEV A+ NF+ H + +A +S H+Y+QML+Y
Sbjct: 273 NWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMY 331
Query: 333 PYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIP 392
PY + N R + A AV AL V+G+ Y +G STTLYV+SG ++DWAY +GI
Sbjct: 332 PYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIK 391
Query: 393 YAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLL 433
YAF+FELRDTG +GFLLP I PT ET +A++ I H L
Sbjct: 392 YAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTL 432
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 296 bits (757), Expect = 3e-80
Identities = 154/401 (38%), Positives = 233/401 (58%), Gaps = 9/401 (2%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94
+ GD+V+R + K E++ L + KVD W+ + D+ +P + + +
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RPSLPVDMRVPFSELKDI 92
Query: 95 LAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHL 152
A+L+ + Y ++I+D+Q L E+ + ++R RS + ++Y YH+LEEI +W+ +
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212
HS ++ IG S+E +S+ +LK A+WID GIH+REWI A W +
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANK 212
Query: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272
+ Y D + +LN + +I V N DG+ F+ + +R WRK +S C GVD NR
Sbjct: 213 IVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNR 272
Query: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332
NWK + G++ +PC +TY GP P+SEPEV A+ NF+ H + +A +S H+Y+QML+Y
Sbjct: 273 NWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMY 331
Query: 333 PYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIP 392
PY + N R + A AV AL V+G+ Y +G STTLYV+SG ++DWAY +GI
Sbjct: 332 PYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIK 391
Query: 393 YAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLL 433
YAF+FELRDTG +GFLLP I PT ET +A++ I H L
Sbjct: 392 YAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTL 432
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 294 bits (752), Expect = 1e-79
Identities = 155/401 (38%), Positives = 233/401 (58%), Gaps = 9/401 (2%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94
+ G +V+R E + +K++ L++D W+ + G+ DV +P +A+
Sbjct: 20 FVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPA----HPGSPIDVRVPFPSIQAV 75
Query: 95 LAFLQEANIQYKVLIEDLQKTL-EKGSSLHTQRNR-RSLSGYNYEVYHSLEEIQNWMHHL 152
FL+ I Y+ +IED+Q L E+ + R+R RS +NY YH+LEEI +++ L
Sbjct: 76 KIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLL 135
Query: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212
+ L+ IG +YEGR +++LK + A+WID GIH+REW+ A WF K+
Sbjct: 136 VAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKK 195
Query: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272
Y D A +L+ L ++ V N DG+ F+ + +R WRKTRS + C GVD NR
Sbjct: 196 ITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNR 255
Query: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332
NW + GAS +PC +TY G F SE EVK++ +F++ H +I+A++S H+Y+Q+L+Y
Sbjct: 256 NWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH-GNIKAFISIHSYSQLLMY 314
Query: 333 PYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIP 392
PY YK +P+ ++ + AV AL S+YG ++ YG +Y +SGS++DW Y GI
Sbjct: 315 PYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIK 374
Query: 393 YAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLL 433
Y+F FELRDTG +GFLLP I PT ET LA+ I H L
Sbjct: 375 YSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 293 bits (750), Expect = 2e-79
Identities = 135/139 (97%), Positives = 136/139 (97%), Gaps = 2/139 (1%)
Query: 149 MHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQW 208
MHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQW
Sbjct: 1 MHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQW 60
Query: 209 FVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGV 268
FVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGV
Sbjct: 61 FVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGV 120
Query: 269 DANRNWKVKWCD--EGASM 285
DANRNWKVKWCD G+SM
Sbjct: 121 DANRNWKVKWCDVSSGSSM 139
Score = 130 bits (328), Expect = 2e-30
Identities = 61/61 (100%), Positives = 61/61 (100%)
Query: 377 VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKC 436
VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKC
Sbjct: 133 VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKC 192
Query: 437 P 437
P
Sbjct: 193 P 193
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 226 bits (577), Expect = 2e-59
Identities = 124/361 (34%), Positives = 188/361 (52%), Gaps = 42/361 (11%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLA 96
+ +V+ +P+T + L+ ++ ++ LWQP + + + + + + A
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82
Query: 97 FLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTH 156
L + I VL+ D++ +++ S T R S S YE YHSL EI +W+ + + H
Sbjct: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS--YYEQYHSLNEIYSWIEFITERH 140
Query: 157 SGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 141 PDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG---- 196
Query: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
++R WRK RS + C G D NRN+
Sbjct: 197 ---------------------------------HNRMWRKNRSFYANNHCIGTDLNRNFA 223
Query: 276 VK-WCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
K WC+EGAS C +TYCG +PESEPEVKAVA+FLR++ I+AY+S H+Y+Q +++PY
Sbjct: 224 SKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY 283
Query: 335 SYKYATIPNFRCVESAAYKAVNALQSV-YGVRYRYGPASTTLYVSSGSSMDWAYKNGIPY 393
SY + + + A +AV A++ RY +G S TLY++ G DW Y GI Y
Sbjct: 284 SYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKY 343
Query: 394 A 394
+
Sbjct: 344 S 344
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 205 bits (522), Expect = 6e-53
Identities = 107/313 (34%), Positives = 173/313 (55%), Gaps = 9/313 (2%)
Query: 37 YAGDKVIRFIPKTEEEAYALKKIS--YQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRAL 94
+ GD+V+R + K E++ L + KVD W+ + D+ +P + + +
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RPSLPVDMRVPFSELKDI 92
Query: 95 LAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHL 152
A+L+ + Y ++I+D+Q L E+ + ++R RS + ++Y YH+LEEI +W+ +
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 153 NKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKE 212
HS ++ IG S+E +S+ +LK A+WID GIH+REWI A W +
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANK 212
Query: 213 ALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 272
+ Y D + +LN + +I V N DG+ F+ + +R WRK +S C GVD NR
Sbjct: 213 IVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNR 272
Query: 273 NWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLY 332
NWK + G++ +PC +TY GP P+SEPEV A+ NF+ H + +A +S H+Y+QML+Y
Sbjct: 273 NWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMY 331
Query: 333 PYSYKYATIPNFR 345
PY + N R
Sbjct: 332 PYGRLLEPVSNQR 344
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWID----CG 194
YH E ++ ++ + + +S + H+ SIG+S +GR+L++L +GR + R +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
+H E +G + + + DP + ++N +IMP N DG+ D ++
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
R +++ D NRN+ D + +PE AV +L+
Sbjct: 142 IGRENYNQY-----DLNRNF--------------PDAFEYNNVSRQPETVAVMKWLKTET 182
Query: 315 KHIRAYLSFHAYAQMLLYPY 334
+ A L H A + YP+
Sbjct: 183 FVLSANL--HGGALVASYPF 200
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWID----CG 194
YH E ++ ++ + + +S + H+ SIG+S +GR+L++L +GR + R +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
+H E +G + + + DP + ++N +IMP N DG+ D ++
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
R +++ D NRN+ D + +PE AV +L+
Sbjct: 142 IGRENYNQY-----DLNRNF--------------PDAFEYNNVSRQPETVAVMKWLKTET 182
Query: 315 KHIRAYLSFHAYAQMLLYPY 334
+ A L H A + YP+
Sbjct: 183 FVLSANL--HGGALVASYPF 200
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWID----CG 194
YH E ++ ++ + + +S + H+ SIG+S +GR+L++L +GR + R +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
+H E +G + + + DP + ++N +IMP N DG+ D ++
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
R +++ D NRN+ D + +PE AV +L+
Sbjct: 142 IGRENYNQY-----DLNRNF--------------PDAFEYNNVSRQPETVAVMKWLKTET 182
Query: 315 KHIRAYLSFHAYAQMLLYPY 334
+ A L H A + YP+
Sbjct: 183 FVLSANL--HGGALVASYPF 200
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 50.1 bits (118), Expect = 4e-06
Identities = 48/227 (21%), Positives = 94/227 (41%), Gaps = 34/227 (14%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCG 194
+H+ + ++ M + + + ++SIG+SY+G L+++++ G + V G
Sbjct: 299 HHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAG 358
Query: 195 IHAREWIGP----AFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTND 250
+H E +G Q+ E L + +P + ++L+ + +++P N DGY ++
Sbjct: 359 MHGNEALGRELLLLLMQFLCHEFL---RGNPRVTRLLSEMRIHLLPSMNPDGYEIAY--H 413
Query: 251 RFWRKTRSRNSRFRCRGVDANRN--------WKVKWCDEGASMH-------PCDDTYCGP 295
R R+ + +D N N W+ + D+G H P Y P
Sbjct: 414 RGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQ--DDGKVPHIVPNHHLPLPTYYTLP 471
Query: 296 FPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIP 342
PE +AV ++ K I LS + + L+ Y + P
Sbjct: 472 NATVAPETRAVIKWM----KRIPFVLSANLHGGELVVSYPFDMTRTP 514
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 49.3 bits (116), Expect = 7e-06
Identities = 51/263 (19%), Positives = 108/263 (41%), Gaps = 33/263 (12%)
Query: 104 QYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMF 163
+++ LI+DL + E G R+ +L+ Y YHS +++ ++ L + + ++
Sbjct: 901 EFETLIKDL--SAENGLESLMLRSSSNLALALYR-YHSYKDLSEFLRGLVMNYPHITNLT 957
Query: 164 SIGRSYEGRSLFILKLGRRSRLKRA----VWIDCGIHAREWIGPAFCQWFVKEALLTYKS 219
++G+S E R ++ L++ + + + GIH +G + L YK
Sbjct: 958 NLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKK 1017
Query: 220 DPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWC 279
+PA+ ++++ I+P N DG + D S+ + RG D + ++
Sbjct: 1018 NPAVTQLVDRTRIVIVPSLNPDGRERAQEKD-----CTSKIGQTNARGKDLDTDFTNN-- 1070
Query: 280 DEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYA 339
S+PE KA+ L + ++ ++ + ++ YPY
Sbjct: 1071 ------------------ASQPETKAIIENLIQ-KQDFSLSVALDGGSMLVTYPYDKPVQ 1111
Query: 340 TIPNFRCVESAAYKAVNALQSVY 362
T+ N ++ A N S++
Sbjct: 1112 TVENKETLKHLASLYANNHPSMH 1134
Score = 47.4 bits (111), Expect = 3e-05
Identities = 52/226 (23%), Positives = 96/226 (42%), Gaps = 40/226 (17%)
Query: 136 YEVYHSLEEIQNWMHHLNKTH-SGLIHMFSIGRSYEGRSLFILKL--GRRSRLKRA---- 188
++ Y+ EE+++ + GL +FSIGRS EGR L++L+L G S +
Sbjct: 55 FDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGP 114
Query: 189 -----------------VWIDCGIHAREWIGPAFCQWFVKEALLTYK-SDPAMRKMLNHL 230
V + +H E + + +E Y+ DP + ++LN
Sbjct: 115 DAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTT 174
Query: 231 YFYIMPVFNVDGYHFSWTNDRFWRK--TRSRNSRFRCRGVDANRNWKVKWCDEGASMHPC 288
Y++P N DG+ + D + + R RG D NR++ D+ ++ P
Sbjct: 175 DVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFP----DQFSTGEP- 229
Query: 289 DDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
P + PEV+A+ ++R+++ + L H + + YP+
Sbjct: 230 ------PALDEVPEVRALIEWIRRNKFVLSGNL--HGGSVVASYPF 267
Score = 45.8 bits (107), Expect = 8e-05
Identities = 36/200 (18%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDC----G 194
+H +++ ++ + + ++S+G+S E R L+++++ + +
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 195 IHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWR 254
+H E +G ++ + +DP + ++++ ++MP N DGY S D
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
Query: 255 KTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHR 314
R+ ++ F D NRN+ D + ++PE AV ++++ +
Sbjct: 623 IGRNNSNNF-----DLNRNF--------------PDQFVQITDPTQPETIAVMSWMKSYP 663
Query: 315 KHIRAYLSFHAYAQMLLYPY 334
+ A L H + ++ YP+
Sbjct: 664 FVLSANL--HGGSLVVNYPF 681
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 45.8 bits (107), Expect = 8e-05
Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 24/215 (11%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCG 194
+H +++ ++ + G+ ++SIGRS EGR L++L+ G L+ V
Sbjct: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
Query: 195 IHAREWIGPAFCQWFVKEALLTYKS-DPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFW 253
+H E +G + +++ + + +++ +I+P N DGY +
Sbjct: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 142
Query: 254 RKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCG-----PFPES-----EPEV 303
K R GVD NRN+ D ++ ++ Y G P P++ EPE
Sbjct: 143 NKPGYLVGRNNANGVDLNRNFP----DLNTYIY-YNEKYGGPNHHLPLPDNWKSQVEPET 197
Query: 304 KAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKY 338
+AV ++ + A L H A + YPY +
Sbjct: 198 RAVIRWMHSFNFVLSANL--HGGAVVANYPYDKSF 230
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 152 LNKTHSGLIHM---FSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCGIHAREWIGPA 204
L +T S H+ +SIGRS++GR L +++ G+ ++ V + IH E G
Sbjct: 60 LRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGRE 119
Query: 205 ----FCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRN 260
Q+ E LL +P ++++LN +++P N DGY + + S
Sbjct: 120 MLIYLAQYLCSEYLL---GNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTS-- 174
Query: 261 SRFRCRGVDANRNW 274
R + +D NRN+
Sbjct: 175 GRQNAQNLDLNRNF 188
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 152 LNKTHSGLIHM---FSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCGIHAREWIGPA 204
L +T S H+ +SIGRS++GR L +++ G+ ++ V + IH E G
Sbjct: 186 LRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGRE 245
Query: 205 ----FCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRN 260
Q+ E LL +P ++++LN +++P N DGY + + S
Sbjct: 246 MLIYLAQYLCSEYLL---GNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTS-- 300
Query: 261 SRFRCRGVDANRNW 274
R + +D NRN+
Sbjct: 301 GRQNAQNLDLNRNF 314
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 152 LNKTHSGLIHM---FSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCGIHAREWIGPA 204
L +T S H+ +SIGRS++GR L +++ G+ ++ V + IH E G
Sbjct: 197 LRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGRE 256
Query: 205 ----FCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRN 260
Q+ E LL +P ++++LN +++P N DGY + + S
Sbjct: 257 MLIYLAQYLCSEYLL---GNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTS-- 311
Query: 261 SRFRCRGVDANRNW 274
R + +D NRN+
Sbjct: 312 GRQNAQNLDLNRNF 325
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 17/169 (10%)
Query: 117 EKGSSLHTQRNRRSLS---GYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRS 173
E G+ R RR L G ++E YH E++ + + + + ++++GRS+EGR
Sbjct: 29 EPGAPAAGMRRRRRLQQEDGISFE-YHRYPELREALVSVWLQCTAISRIYTVGRSFEGRE 87
Query: 174 LFILKLGRRSRLKRAVWIDC----GIHAREWIGPAFCQWFVKEALLTY-KSDPAMRKMLN 228
L +++L + + +H E +G + + Y K + + +++
Sbjct: 88 LLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIH 147
Query: 229 HLYFYIMPVFNVDGYHFSWTND---RFWRKTRSRNSRFRCRGVDANRNW 274
+IMP N DG+ + + + W RS +G+D NRN+
Sbjct: 148 STRIHIMPSLNPDGFEKAASQPGELKDWFVGRS-----NAQGIDLNRNF 191
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 37.0 bits (84), Expect = 0.035
Identities = 22/110 (20%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCG 194
+HS ++++ M +N+ + +S+G+S G ++ +++ G + G
Sbjct: 564 HHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAG 623
Query: 195 IHAREWIGPAFCQWFVKEALLTYK-SDPAMRKMLNHLYFYIMPVFNVDGY 243
IH E +G ++ Y+ +P +R ++ +++P N DGY
Sbjct: 624 IHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGY 673
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 33.1 bits (74), Expect = 0.51
Identities = 22/110 (20%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Query: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCG 194
+H+ +E++ M +N+ + +++IG+S++G L+ +++ G + G
Sbjct: 318 HHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAG 377
Query: 195 IHAREWIGPAFCQWFVKEALLTYKSDPA-MRKMLNHLYFYIMPVFNVDGY 243
H E +G V+ Y + A + ++ +++P N DGY
Sbjct: 378 AHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGY 427
>gi|120444924 ATP/GTP binding protein-like 1 [Homo sapiens]
Length = 1066
Score = 32.0 bits (71), Expect = 1.1
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 14/81 (17%)
Query: 195 IHAREWIGPAFCQWFVKEAL-LTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFW 253
I AR G + W +K L SDP R + + F I+P+ N DG
Sbjct: 753 ITARVHPGESNASWVMKGTLEFLVSSDPVARLLRENFIFKIIPMLNPDG----------- 801
Query: 254 RKTRSRNSRFRCRGVDANRNW 274
+ N R G D NR W
Sbjct: 802 --VINGNHRCSLSGEDLNRQW 820
>gi|45237195 Janus kinase and microtubule interacting protein 2
[Homo sapiens]
Length = 810
Score = 30.8 bits (68), Expect = 2.5
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 98 LQEANIQYKVLIEDLQKTL-EKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNK 154
LQ ++YK IEDL+ TL +KG H +++ N E+ +E+ + H L +
Sbjct: 515 LQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQ 572
>gi|239752401 PREDICTED: hypothetical protein [Homo sapiens]
Length = 250
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/61 (29%), Positives = 24/61 (39%)
Query: 317 IRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLY 376
I AY+ H Y M Y Y+Y Y + + + AY + VY Y Y Y
Sbjct: 23 IYAYVCIHIYVYMRTYVYTYMYICVRMYTHICMYAYVYICTCMCVYMHMYVYVHMHVYAY 82
Query: 377 V 377
V
Sbjct: 83 V 83
>gi|239754336 PREDICTED: hypothetical protein [Homo sapiens]
Length = 232
Score = 30.0 bits (66), Expect = 4.3
Identities = 13/42 (30%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 315 KHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVN 356
+HI Y+ H Y + +Y Y Y Y + + CV + AY ++
Sbjct: 15 RHIYVYIHIHTY--VYIYMYIYTYICMYTYICVYTHAYLCIH 54
>gi|239748878 PREDICTED: similar to serine/threonine-protein kinase,
putative [Homo sapiens]
Length = 230
Score = 30.0 bits (66), Expect = 4.3
Identities = 14/54 (25%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 315 KHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRY 368
+HI Y+ H Y + +Y Y Y Y + + CV + Y ++ ++ Y Y
Sbjct: 15 RHIYVYIHIHTY--VYIYMYIYTYILMYTYICVYTHTYLCIHTYVYIHMHTYVY 66
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,028,091
Number of Sequences: 37866
Number of extensions: 736486
Number of successful extensions: 2283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2154
Number of HSP's gapped (non-prelim): 94
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.