Guide to the Human Genome
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Search of human proteins with 187281517

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187281517 cytosolic phosphoenolpyruvate carboxykinase 1
[Homo sapiens]
         (622 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187281517 cytosolic phosphoenolpyruvate carboxykinase 1 [Homo...  1291   0.0  
gi|66346721 mitochondrial phosphoenolpyruvate carboxykinase 2 is...   942   0.0  
gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2 is...   600   e-172
gi|13129110 WD repeat domain 77 [Homo sapiens]                         31   3.9  
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]         30   5.1  
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]          30   5.1  
gi|241982689 ADP-ribosylation factor-like 13 isoform b [Homo sap...    30   6.6  
gi|241982687 ADP-ribosylation factor-like 13 isoform a [Homo sap...    30   6.6  
gi|124248533 ADP-ribosylation factor-like 13 isoform a [Homo sap...    30   6.6  
gi|223633959 proline-rich acidic protein 1 isoform 1 [Homo sapiens]    30   8.7  
gi|223633957 proline-rich acidic protein 1 isoform 2 [Homo sapiens]    30   8.7  
gi|21265037 ADAM metallopeptidase with thrombospondin type 1 mot...    30   8.7  

>gi|187281517 cytosolic phosphoenolpyruvate carboxykinase 1 [Homo
           sapiens]
          Length = 622

 Score = 1291 bits (3340), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQM 60
           MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQM
Sbjct: 1   MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQM 60

Query: 61  EEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEE 120
           EEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEE
Sbjct: 61  EEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEE 120

Query: 121 DFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV 180
           DFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV
Sbjct: 121 DFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV 180

Query: 181 LEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL 240
           LEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL
Sbjct: 181 LEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL 240

Query: 241 LGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSL 300
           LGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSL
Sbjct: 241 LGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSL 300

Query: 301 PGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV 360
           PGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV
Sbjct: 301 PGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV 360

Query: 361 AETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAW 420
           AETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAW
Sbjct: 361 AETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAW 420

Query: 421 ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPF 480
           ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPF
Sbjct: 421 ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPF 480

Query: 481 AMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM 540
           AMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM
Sbjct: 481 AMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM 540

Query: 541 FNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQV 600
           FNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQV
Sbjct: 541 FNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQV 600

Query: 601 NADLPCEIEREILALKQRISQM 622
           NADLPCEIEREILALKQRISQM
Sbjct: 601 NADLPCEIEREILALKQRISQM 622


>gi|66346721 mitochondrial phosphoenolpyruvate carboxykinase 2
           isoform 1 precursor [Homo sapiens]
          Length = 640

 Score =  942 bits (2436), Expect = 0.0
 Identities = 436/610 (71%), Positives = 517/610 (84%), Gaps = 1/610 (0%)

Query: 14  KVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYD 73
           +V+ G L  LP  +R+F+E++A LCQP+ IHICDG+E EN   L  +E++G++R+L KY+
Sbjct: 31  RVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYN 90

Query: 74  NCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGL-SQLGRWMSEEDFEKAFNARFPG 132
           NCWLA TDP+DVAR+ESKTVIVT  QRDTV +P  G   QLG WMS  DF++A + RFPG
Sbjct: 91  NCWLARTDPKDVARVESKTVIVTPSQRDTVQLPPGGARGQLGNWMSPADFQRAVDERFPG 150

Query: 133 CMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKC 192
           CM+GRTMYV+PFSMGP+GSPLS+IG++LTDS YVVASMRIMTR+GTPVL+A+GDG+FVKC
Sbjct: 151 CMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGDGDFVKC 210

Query: 193 LHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMAS 252
           LHSVG PL  Q   V+ WPCNPE TLI H+PD+REIISFGSGYGGNSLLGKKCFALR+AS
Sbjct: 211 LHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIAS 270

Query: 253 RLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDI 312
           RLA++EGWLAEHMLILGIT+P G+K+Y+AAAFPSACGKTNLAMM P+LPGWKVECVGDDI
Sbjct: 271 RLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDI 330

Query: 313 AWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEG 372
           AWM+FD++G LRAINPENGFFGVAPGTS  TNPNA+ TIQ NTIFTNVAETSDGGVYWEG
Sbjct: 331 AWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEG 390

Query: 373 IDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGII 432
           ID+PL  GVT+TSW  K W   D EPCAHPNSRFC PA QCPI+D AWE+PEGVPI+ II
Sbjct: 391 IDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAII 450

Query: 433 FGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGK 492
           FGGRRP GVPLVYEA +W+HGVFVG+AMRSE+TAAAEHKGKIIMHDPFAMRPFFGYNFG 
Sbjct: 451 FGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGH 510

Query: 493 YLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKL 552
           YL HWLSM     A+LP+IFHVNWFR+D+ G FLWPGFGEN+RVL+W+  R++G+ S + 
Sbjct: 511 YLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARVLDWICRRLEGEDSARE 570

Query: 553 TPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREI 612
           TPIG +PKE AL+L GL  I+  +LFS+ K+FWE+EV DI  YL +QVN DLP E+  E+
Sbjct: 571 TPIGLVPKEGALDLSGLRAIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAEL 630

Query: 613 LALKQRISQM 622
            AL++R+ +M
Sbjct: 631 EALERRVHKM 640


>gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2
           isoform 2 precursor [Homo sapiens]
          Length = 441

 Score =  600 bits (1548), Expect = e-172
 Identities = 283/392 (72%), Positives = 332/392 (84%), Gaps = 3/392 (0%)

Query: 14  KVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYD 73
           +V+ G L  LP  +R+F+E++A LCQP+ IHICDG+E EN   L  +E++G++R+L KY+
Sbjct: 31  RVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYN 90

Query: 74  NCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGL-SQLGRWMSEEDFEKAFNARFPG 132
           NCWLA TDP+DVAR+ESKTVIVT  QRDTV +P  G   QLG WMS  DF++A + RFPG
Sbjct: 91  NCWLARTDPKDVARVESKTVIVTPSQRDTVQLPPGGARGQLGNWMSPADFQRAVDERFPG 150

Query: 133 CMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKC 192
           CM+GRTMYV+PFSMGP+GSPLS+IG++LTDS YVVASMRIMTR+GTPVL+A+GDG+FVKC
Sbjct: 151 CMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGDGDFVKC 210

Query: 193 LHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMAS 252
           LHSVG PL  Q   V+ WPCNPE TLI H+PD+REIISFGSGYGGNSLLGKKCFALR+AS
Sbjct: 211 LHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIAS 270

Query: 253 RLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDI 312
           RLA++EGWLAEHMLILGIT+P G+K+Y+AAAFPSACGKTNLAMM P+LPGWKVECVGDDI
Sbjct: 271 RLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDI 330

Query: 313 AWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEG 372
           AWM+FD++G LRAINPENGFFGVAPGTS  TNPNA+ TIQ NTIFTNVAETSDGGVYWEG
Sbjct: 331 AWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEG 390

Query: 373 IDEPLASGVTITSWKNKEWSSE--DGEPCAHP 402
           ID+PL  GVT+TSW  K W      GE  A P
Sbjct: 391 IDQPLPPGVTVTSWLGKPWKPGMCGGEGVAQP 422


>gi|13129110 WD repeat domain 77 [Homo sapiens]
          Length = 342

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 4/51 (7%)

Query: 378 ASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPA--SQCPIIDAAWESPEGV 426
           AS ++   W    W  +D  PCA PN  FC+    ++  + D  W    G+
Sbjct: 46  ASSLSGRCWAGSLWLFKD--PCAAPNEGFCSAGVQTEAGVADLTWVGERGI 94


>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
          Length = 525

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 199 PLPLQKPLVNNW-PCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKE 257
           PLP ++P+ N+  P +P L       ++ E ++   G+  +SLL +K        RL ++
Sbjct: 408 PLPAERPIFNSMAPASPRLL------NQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEK 461

Query: 258 EGWLAEHMLILGITNPEGEKKYL 280
           + WL     +     P+ E + L
Sbjct: 462 KTWLTNGFDVFECPPPKTENELL 484


>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
          Length = 525

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 199 PLPLQKPLVNNW-PCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKE 257
           PLP ++P+ N+  P +P L       ++ E ++   G+  +SLL +K        RL ++
Sbjct: 408 PLPAERPIFNSMAPASPRLL------NQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEK 461

Query: 258 EGWLAEHMLILGITNPEGEKKYL 280
           + WL     +     P+ E + L
Sbjct: 462 KTWLTNGFDVFECPPPKTENELL 484


>gi|241982689 ADP-ribosylation factor-like 13 isoform b [Homo
           sapiens]
          Length = 256

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 96  TQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMK 135
           T+E R  V IP  GL+  G+ +  E F+K   ++   CMK
Sbjct: 15  TEETRRNVTIPIIGLNNSGKTVLVEAFQKLLPSKTDHCMK 54


>gi|241982687 ADP-ribosylation factor-like 13 isoform a [Homo
           sapiens]
          Length = 290

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 96  TQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMK 135
           T+E R  V IP  GL+  G+ +  E F+K   ++   CMK
Sbjct: 15  TEETRRNVTIPIIGLNNSGKTVLVEAFQKLLPSKTDHCMK 54


>gi|124248533 ADP-ribosylation factor-like 13 isoform a [Homo
           sapiens]
          Length = 290

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 96  TQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMK 135
           T+E R  V IP  GL+  G+ +  E F+K   ++   CMK
Sbjct: 15  TEETRRNVTIPIIGLNNSGKTVLVEAFQKLLPSKTDHCMK 54


>gi|223633959 proline-rich acidic protein 1 isoform 1 [Homo sapiens]
          Length = 151

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 93  VIVTQEQRDTVPIPKTGLS-QLGRWMSEEDFEKAFNAR 129
           V+V   +   VP PK  +  Q+  W SE+D EKA+ AR
Sbjct: 11  VVVLLWEAGAVPAPKVPIKMQVKHWPSEQDPEKAWGAR 48


>gi|223633957 proline-rich acidic protein 1 isoform 2 [Homo sapiens]
          Length = 142

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 93  VIVTQEQRDTVPIPKTGLS-QLGRWMSEEDFEKAFNAR 129
           V+V   +   VP PK  +  Q+  W SE+D EKA+ AR
Sbjct: 11  VVVLLWEAGAVPAPKVPIKMQVKHWPSEQDPEKAWGAR 48


>gi|21265037 ADAM metallopeptidase with thrombospondin type 1 motif,
           3 proprotein [Homo sapiens]
          Length = 1205

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 9/62 (14%)

Query: 188 EFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFA 247
           E  + +HS  C L    P  ++WP  PEL  I +  D +    FG GY       K C A
Sbjct: 445 ELKRYIHSYDCLL--DDPFDHDWPKLPELPGINYSMDEQCRFDFGVGY-------KMCTA 495

Query: 248 LR 249
            R
Sbjct: 496 FR 497


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,000,576
Number of Sequences: 37866
Number of extensions: 1269052
Number of successful extensions: 2630
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2620
Number of HSP's gapped (non-prelim): 12
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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