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Search of human proteins with 10518344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
(183 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 364 e-101
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 338 2e-93
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 331 2e-91
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 227 5e-60
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 227 5e-60
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 223 9e-59
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 223 9e-59
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 177 3e-45
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 177 3e-45
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 176 1e-44
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 176 1e-44
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 175 2e-44
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 175 2e-44
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 172 2e-43
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 167 5e-42
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 165 2e-41
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 165 2e-41
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 164 3e-41
gi|21703367 Di-Ras2 [Homo sapiens] 162 2e-40
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 160 4e-40
gi|145386506 muscle RAS oncogene homolog [Homo sapiens] 156 8e-39
gi|145386562 muscle RAS oncogene homolog [Homo sapiens] 156 8e-39
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 156 1e-38
gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo... 133 1e-31
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 132 1e-31
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 130 8e-31
gi|169160721 PREDICTED: similar to related RAS viral (r-ras) onc... 129 1e-30
gi|169161589 PREDICTED: similar to related RAS viral (r-ras) onc... 129 1e-30
gi|169161292 PREDICTED: similar to related RAS viral (r-ras) onc... 129 1e-30
gi|22027486 RASD family, member 2 [Homo sapiens] 118 3e-27
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 364 bits (935), Expect = e-101
Identities = 183/183 (100%), Positives = 183/183 (100%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180
ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
Sbjct: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180
Query: 181 NIQ 183
NIQ
Sbjct: 181 NIQ 183
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 338 bits (866), Expect = 2e-93
Identities = 167/183 (91%), Positives = 176/183 (96%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI+RVKRYEKVP+ILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180
E EREV SSEGRALA+EWGCPFMETSAKSK+MVDELFAEIVRQMNY++ P+K D CC+ C
Sbjct: 121 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC 180
Query: 181 NIQ 183
+Q
Sbjct: 181 VVQ 183
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 331 bits (849), Expect = 2e-91
Identities = 166/182 (91%), Positives = 173/182 (95%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYKVVVLGSGGVGKSALTVQFVTG+FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
Sbjct: 1 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYE+VP+ILVGNKVDL
Sbjct: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC 180
E EREVS EG+ALAEEW CPFMETSAK+K VDELFAEIVRQMNYAAQP+ D+ CCSAC
Sbjct: 121 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC 180
Query: 181 NI 182
I
Sbjct: 181 VI 182
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 227 bits (578), Expect = 5e-60
Identities = 113/181 (62%), Positives = 140/181 (77%), Gaps = 1/181 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK E VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSA 179
E ER V +G+ LA +W C F+E+SAKSK V+E+F ++VRQ+N +K P +
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 C 180
C
Sbjct: 181 C 181
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 227 bits (578), Expect = 5e-60
Identities = 113/181 (62%), Positives = 140/181 (77%), Gaps = 1/181 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK E VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSA 179
E ER V +G+ LA +W C F+E+SAKSK V+E+F ++VRQ+N +K P +
Sbjct: 121 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 180
Query: 180 C 180
C
Sbjct: 181 C 181
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 223 bits (567), Expect = 9e-59
Identities = 109/166 (65%), Positives = 136/166 (81%), Gaps = 1/166 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD+ +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK + VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMN 165
E ER V +G+ LA +W C F+E+SAKSK V+E+F ++VRQ+N
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 223 bits (567), Expect = 9e-59
Identities = 109/166 (65%), Positives = 136/166 (81%), Gaps = 1/166 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
MREYK+VVLGSGGVGKSALTVQFV G F+EKYDPTIED YRK++EVD+ +LEILDTAG
Sbjct: 1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
TEQF +MRDLY+KNGQGF LVYS+ Q +F D++ +R+QI+RVK + VP+ILVGNK DL
Sbjct: 61 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMN 165
E ER V +G+ LA +W C F+E+SAKSK V+E+F ++VRQ+N
Sbjct: 121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN 166
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 177 bits (450), Expect = 3e-45
Identities = 86/185 (46%), Positives = 131/185 (70%), Gaps = 6/185 (3%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQ-----MNYAAQPDKDDP 175
+ R V S + + LA +G P++ETSAK++ V++ F +VR+ + PD+ P
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP 179
Query: 176 CCSAC 180
C +C
Sbjct: 180 GCMSC 184
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 177 bits (450), Expect = 3e-45
Identities = 86/185 (46%), Positives = 131/185 (70%), Gaps = 6/185 (3%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQ-----MNYAAQPDKDDP 175
+ R V S + + LA +G P++ETSAK++ V++ F +VR+ + PD+ P
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGP 179
Query: 176 CCSAC 180
C +C
Sbjct: 180 GCMSC 184
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 176 bits (446), Expect = 1e-44
Identities = 84/164 (51%), Positives = 124/164 (75%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK E VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
S R V + + + LA +G PF+ETSAK++ VD+ F +VR++
Sbjct: 121 PS-RTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREI 163
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 176 bits (446), Expect = 1e-44
Identities = 81/163 (49%), Positives = 121/163 (74%)
Query: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61
REYK+V+LG+GGVGKSA+T+QF++ F E +DPTIED Y+ I +D P+ L+ILDTAG
Sbjct: 20 REYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKIRIRIDDEPANLDILDTAGQ 79
Query: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
+F +MRD Y++ G+GFI+ YS+ +++SF +++ + I RV+R + PV+LVGNK DL+
Sbjct: 80 AEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVRRTDDTPVVLVGNKSDLK 139
Query: 122 SEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
R+V+ EG ALA E+ CPF ETSA + +D++F +VR++
Sbjct: 140 QLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVREI 182
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 175 bits (444), Expect = 2e-44
Identities = 83/164 (50%), Positives = 124/164 (75%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK E VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
S R V + + + LA +G PF+ETSAK++ V++ F +VR++
Sbjct: 121 PS-RTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREI 163
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 175 bits (443), Expect = 2e-44
Identities = 78/163 (47%), Positives = 124/163 (76%)
Query: 2 REYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61
REYKVV+LG+GGVGKSA+T+QF++ F + +DPTIED Y+ ++ +D+ P+ L+ILDTAG
Sbjct: 19 REYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQ 78
Query: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
+F +MR+ Y++ G+GFI+ YS+ ++QSFQ+ ++ I +V+ ++P++LVGNK+DLE
Sbjct: 79 AEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLE 138
Query: 122 SEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
R+VS+ EG +LA+E+ C F ETSA + +D+ F +VR++
Sbjct: 139 QFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREI 181
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 172 bits (435), Expect = 2e-43
Identities = 81/164 (49%), Positives = 123/164 (75%), Gaps = 1/164 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
+ R V + + LA+ +G PF+ETSAK++ V++ F +VR++
Sbjct: 121 PT-RTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREI 163
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 167 bits (423), Expect = 5e-42
Identities = 79/172 (45%), Positives = 122/172 (70%), Gaps = 1/172 (0%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+KV+++GSGGVGKSALT+QF+ F+E Y+PT D YRK++ +D ++ILDTAG E
Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYE-KVPVILVGNKVDLES 122
+A++RD Y ++G+GF+LV+S+ +SF R+QI+RVK E K+P+++VGNK DLE
Sbjct: 75 YAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEE 134
Query: 123 EREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDD 174
R+V E R+ AEEWG ++ETSAK++ VD++F +++R++ + D
Sbjct: 135 RRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKD 186
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 165 bits (417), Expect = 2e-41
Identities = 77/171 (45%), Positives = 119/171 (69%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+KV+++GSGGVGKSALT+QF+ F+E Y+PT D YRK++ +D ++ILDTAG E
Sbjct: 15 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQED 74
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
+A++RD Y ++G+GF+ V+S+ +SF R+QI+RVK E VP +LVGNK DLE +
Sbjct: 75 YAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDK 134
Query: 124 REVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDD 174
R+VS E + AE+W ++ETSAK++ VD++F +++R++ D +
Sbjct: 135 RQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKE 185
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 165 bits (417), Expect = 2e-41
Identities = 77/160 (48%), Positives = 117/160 (73%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y++VV+G GGVGKSALT+QF+ F+ YDPTIED Y K+ +D + L+ILDTAG E
Sbjct: 14 KYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQE 73
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLES 122
+F +MR+ Y++ G+GF+LV+S+ ++ SF++I + QI+RVK ++ P+IL+GNK DL+
Sbjct: 74 EFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDH 133
Query: 123 EREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVR 162
+R+V+ EG+ LA + +ME SAK + VD+ F E+VR
Sbjct: 134 QRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVR 173
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 164 bits (416), Expect = 3e-41
Identities = 77/150 (51%), Positives = 115/150 (76%), Gaps = 1/150 (0%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
M EYK+VV+G+GGVGKSALT+Q + F+++YDPTIED YRK++ +D +L+ILDTAG
Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG 60
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
E++++MRD Y++ G+GF+ V+++ N +SF+DI R+QI RVK + VP++LVGNK DL
Sbjct: 61 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL 120
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSK 150
+ R V S + + LA +G P++ETSAK++
Sbjct: 121 -AARTVESRQAQDLARSYGIPYIETSAKTR 149
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 162 bits (409), Expect = 2e-40
Identities = 82/160 (51%), Positives = 108/160 (67%), Gaps = 1/160 (0%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y+V V G+GGVGKS+L ++FV GTF E Y PT+ED YR+ I D S L+I DT G+
Sbjct: 7 DYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSH 66
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVK-RYEKVPVILVGNKVDLE 121
QF +M+ L I G FILVYS+ ++QS +++KP+ +QI +K E +P++LVGNK D
Sbjct: 67 QFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDES 126
Query: 122 SEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIV 161
REV SSE ALA W C FMETSAK V ELF E++
Sbjct: 127 PSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELL 166
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 160 bits (406), Expect = 4e-40
Identities = 79/159 (49%), Positives = 110/159 (69%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
+K+VV+G GGVGKSALT+QF+ F+ YDPTIED Y K VD P+ L+ILDTAG E+
Sbjct: 30 HKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEE 89
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
F +MR+ Y++ G GF+LV+++ ++QSF ++ + QI+RVK + PV+LVGNK DLES+
Sbjct: 90 FGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQ 149
Query: 124 REVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVR 162
R+V SE A + E SAK + VDE F ++VR
Sbjct: 150 RQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVR 188
>gi|145386506 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 156 bits (395), Expect = 8e-39
Identities = 75/160 (46%), Positives = 113/160 (70%), Gaps = 1/160 (0%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
YK+VV+G GGVGKSALT+QF F+ YDPTIED Y K E+D+ ++L++LDTAG E+
Sbjct: 14 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEE 73
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
F++MR+ Y++ G GF++VYS+ ++ SF+ + I+RVK E P+ILV NKVDL
Sbjct: 74 FSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHL 133
Query: 124 REVSSSEGRALAEEWGCPFMETSAKSKTM-VDELFAEIVR 162
R+++ +G+ +A + P++ETSAK + VD+ F ++VR
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVR 173
>gi|145386562 muscle RAS oncogene homolog [Homo sapiens]
Length = 208
Score = 156 bits (395), Expect = 8e-39
Identities = 75/160 (46%), Positives = 113/160 (70%), Gaps = 1/160 (0%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
YK+VV+G GGVGKSALT+QF F+ YDPTIED Y K E+D+ ++L++LDTAG E+
Sbjct: 14 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEE 73
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
F++MR+ Y++ G GF++VYS+ ++ SF+ + I+RVK E P+ILV NKVDL
Sbjct: 74 FSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHL 133
Query: 124 REVSSSEGRALAEEWGCPFMETSAKSKTM-VDELFAEIVR 162
R+++ +G+ +A + P++ETSAK + VD+ F ++VR
Sbjct: 134 RKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVR 173
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 156 bits (394), Expect = 1e-38
Identities = 80/160 (50%), Positives = 113/160 (70%), Gaps = 2/160 (1%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
+Y+VVV G+GGVGKS+L ++FV GTF + Y PTIED YR+ I D S L+I DT G+
Sbjct: 7 DYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSH 66
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVK-RYEKVPVILVGNKVDLE 121
QF +M+ L I G FILV+S+ ++QS +++ P+ I+++K E +PV+LVGNK D E
Sbjct: 67 QFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCD-E 125
Query: 122 SEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIV 161
++REV + E +A+A+EW C FMETSAK V ELF E++
Sbjct: 126 TQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELL 165
>gi|14249704 RAS-like, estrogen-regulated, growth inhibitor [Homo
sapiens]
Length = 199
Score = 133 bits (334), Expect = 1e-31
Identities = 68/163 (41%), Positives = 106/163 (65%), Gaps = 2/163 (1%)
Query: 3 EYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTE 62
E K+ + G GVGKSAL V+F+T FI +YDPT+E YR + +D +EILDTAG E
Sbjct: 6 EVKLAIFGRAGVGKSALVVRFLTKRFIWEYDPTLESTYRHQATIDDEVVSMEILDTAGQE 65
Query: 63 QFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLES 122
R+ +++ G+GF+LVY + ++ SF+++ P+++ + +K+ + V +ILVGNK DL+
Sbjct: 66 D-TIQREGHMRWGEGFVLVYDITDRGSFEEVLPLKNILDEIKKPKNVTLILVGNKADLDH 124
Query: 123 EREVSSSEGRALAEEWGCPFMETSA-KSKTMVDELFAEIVRQM 164
R+VS+ EG LA E C F E SA + + E+F E+ R++
Sbjct: 125 SRQVSTEEGEKLATELACAFYECSACTGEGNITEIFYELCREV 167
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 132 bits (333), Expect = 1e-31
Identities = 70/181 (38%), Positives = 113/181 (62%), Gaps = 8/181 (4%)
Query: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQF 64
K+ +LG VGKS+LT+QFV G F++ YDPTIE+ + K I V+ L+++DTAG +++
Sbjct: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEY 67
Query: 65 ASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESER 124
+ Y + G+ILVYS+ + +SF+ IK + +++ + ++P++LVGNK DL ER
Sbjct: 68 SIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMER 127
Query: 125 EVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIV---RQMNYAAQPDKDDPCCSACN 181
+S EG+ALAE W F+E+SAK ++F I+ +M+ AA K S+C+
Sbjct: 128 VISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGK-----SSCS 182
Query: 182 I 182
+
Sbjct: 183 V 183
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 130 bits (326), Expect = 8e-31
Identities = 65/164 (39%), Positives = 103/164 (62%)
Query: 1 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG 60
+R KVV+LG VGK++L QFV G F E YDPT+E+ Y K + + L ++DTAG
Sbjct: 4 VRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTLGKDEFHLHLVDTAG 63
Query: 61 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL 120
++++ + +I G++LVYS+ + SFQ I+ + ++ +VPV+LVGNK DL
Sbjct: 64 QDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADL 123
Query: 121 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
EREV + EG+ LAE WG FME+SA+ + +F ++++++
Sbjct: 124 SPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEI 167
>gi|169160721 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 1e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V+ EGR LA + +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKTMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|169161589 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 1e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V+ EGR LA + +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKTMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|169161292 PREDICTED: similar to related RAS viral (r-ras)
oncogene homolog 2 [Homo sapiens]
Length = 185
Score = 129 bits (324), Expect = 1e-30
Identities = 61/135 (45%), Positives = 94/135 (69%)
Query: 28 FIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQ 87
F+ YDPT ED Y K+ +D + L+ILDTAG E+ +MR+ Y++ G+GF+LV+S+ ++
Sbjct: 20 FVTDYDPTNEDSYTKQCVIDDRAARLDILDTAGQEELGAMREQYMRTGEGFLLVFSVTDR 79
Query: 88 QSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSA 147
SF++I + QI+RVK ++ P+IL+GNK DL+ +R+V+ EGR LA + +ME SA
Sbjct: 80 GSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGRQLARQLKVTYMEASA 139
Query: 148 KSKTMVDELFAEIVR 162
K + VD+ F E+VR
Sbjct: 140 KIRMNVDQAFHELVR 154
>gi|22027486 RASD family, member 2 [Homo sapiens]
Length = 266
Score = 118 bits (295), Expect = 3e-27
Identities = 68/164 (41%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 20 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 79
Query: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEK--------VPVILVG 115
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 80 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 139
Query: 116 NKVDL-ESEREVSSSEGRALAE-EWGCPFMETSAKSKTMVDELF 157
NK D E R+V ++E L + C + E SAK T VDE+F
Sbjct: 140 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,211,923
Number of Sequences: 37866
Number of extensions: 233484
Number of successful extensions: 1089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 217
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 650
Number of HSP's gapped (non-prelim): 268
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.