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Search of human proteins with 18087825
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18087825 aspartoacylase 3 [Homo sapiens]
(319 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18087825 aspartoacylase 3 [Homo sapiens] 650 0.0
gi|4557335 aspartoacylase [Homo sapiens] 289 3e-78
gi|189339202 aspartoacylase [Homo sapiens] 289 3e-78
gi|148806932 kyphoscoliosis peptidase [Homo sapiens] 37 0.023
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 32 0.98
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 32 0.98
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 32 0.98
gi|139394604 bromo adjacent homology domain containing 1 [Homo s... 31 1.3
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 31 1.7
gi|20302168 toll-like receptor 8 [Homo sapiens] 30 2.2
gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [... 30 3.7
gi|39777610 semaphorin 4B precursor [Homo sapiens] 29 6.3
gi|39777608 semaphorin 4B precursor [Homo sapiens] 29 6.3
gi|239756555 PREDICTED: hypothetical protein XP_002344930 [Homo ... 28 8.3
gi|239751056 PREDICTED: hypothetical protein [Homo sapiens] 28 8.3
gi|239745519 PREDICTED: hypothetical protein XP_002343478 [Homo ... 28 8.3
gi|27881501 ATP-binding cassette, sub-family A, member 12 isofor... 28 8.3
gi|30795238 ATP-binding cassette, sub-family A, member 12 isofor... 28 8.3
gi|4757956 cadherin 16 precursor [Homo sapiens] 28 8.3
>gi|18087825 aspartoacylase 3 [Homo sapiens]
Length = 319
Score = 650 bits (1677), Expect = 0.0
Identities = 319/319 (100%), Positives = 319/319 (100%)
Query: 1 MCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSG 60
MCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSG
Sbjct: 1 MCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSG 60
Query: 61 CRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTA 120
CRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTA
Sbjct: 61 CRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTA 120
Query: 121 NMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELG 180
NMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELG
Sbjct: 121 NMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELG 180
Query: 181 PQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLA 240
PQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLA
Sbjct: 181 PQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLA 240
Query: 241 GTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEK 300
GTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEK
Sbjct: 241 GTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEK 300
Query: 301 FTFTVPAMPALTPAPSPAS 319
FTFTVPAMPALTPAPSPAS
Sbjct: 301 FTFTVPAMPALTPAPSPAS 319
>gi|4557335 aspartoacylase [Homo sapiens]
Length = 313
Score = 289 bits (739), Expect = 3e-78
Identities = 138/308 (44%), Positives = 192/308 (62%)
Query: 1 MCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSG 60
M S + E +++VA+ GGTHGNE++GV+L +HWL AE+QR P + NP A
Sbjct: 1 MTSCHIAEEHIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKK 60
Query: 61 CRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTA 120
C RY+D DLNR F L + + D PYEV RA+E+N L GPK S ++D + DLHNTT+
Sbjct: 61 CTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTS 120
Query: 121 NMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELG 180
NMG LI + S F + + +++ L C V+L + + S+AK +G+E+G
Sbjct: 121 NMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVG 180
Query: 181 PQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLA 240
PQPQGVLRADI +MR ++ LDFI FN+G FP +E Y+ + VD+PR E G +A
Sbjct: 181 PQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIA 240
Query: 241 GTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEK 300
+HP LQD+D++PL PG P+F G+ + G+ TVYPVF+NEAAYYEK AF +T K
Sbjct: 241 AIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTK 300
Query: 301 FTFTVPAM 308
T ++
Sbjct: 301 LTLNAKSI 308
>gi|189339202 aspartoacylase [Homo sapiens]
Length = 313
Score = 289 bits (739), Expect = 3e-78
Identities = 138/308 (44%), Positives = 192/308 (62%)
Query: 1 MCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSG 60
M S + E +++VA+ GGTHGNE++GV+L +HWL AE+QR P + NP A
Sbjct: 1 MTSCHIAEEHIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLEVKPFITNPRAVKK 60
Query: 61 CRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTA 120
C RY+D DLNR F L + + D PYEV RA+E+N L GPK S ++D + DLHNTT+
Sbjct: 61 CTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTS 120
Query: 121 NMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELG 180
NMG LI + S F + + +++ L C V+L + + S+AK +G+E+G
Sbjct: 121 NMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVG 180
Query: 181 PQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLA 240
PQPQGVLRADI +MR ++ LDFI FN+G FP +E Y+ + VD+PR E G +A
Sbjct: 181 PQPQGVLRADILDQMRKMIKHALDFIHHFNEGKEFPPCAIEVYKIIEKVDYPRDENGEIA 240
Query: 241 GTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEK 300
+HP LQD+D++PL PG P+F G+ + G+ TVYPVF+NEAAYYEK AF +T K
Sbjct: 241 AIIHPNLQDQDWKPLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTK 300
Query: 301 FTFTVPAM 308
T ++
Sbjct: 301 LTLNAKSI 308
>gi|148806932 kyphoscoliosis peptidase [Homo sapiens]
Length = 661
Score = 37.0 bits (84), Expect = 0.023
Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 7/78 (8%)
Query: 154 VFLYQRSGEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRT-LVATVLDF---IELF 209
+F++ +G++ + L S+ KNG+ LE+ P G + IF++ + + ++VL++
Sbjct: 379 LFMFMLNGKQEHGLLSLRKNGMKLEVYPPTMGTHKLQIFAKGNSDIYSSVLEYTLKCNYV 438
Query: 210 NQGTAFPAFEMEAYRPVG 227
+ G PA E ++PVG
Sbjct: 439 DMGVQLPA---ELHQPVG 453
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 31.6 bits (70), Expect = 0.98
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 161 GEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIEL--FNQGTAFPAF 218
GE SY L++V K+ L +P+G R IF + V + + L F FP
Sbjct: 145 GENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN 204
Query: 219 EMEAYRPV 226
+ Y P+
Sbjct: 205 GWKLYDPL 212
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 31.6 bits (70), Expect = 0.98
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 161 GEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIEL--FNQGTAFPAF 218
GE SY L++V K+ L +P+G R IF + V + + L F FP
Sbjct: 73 GENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN 132
Query: 219 EMEAYRPV 226
+ Y P+
Sbjct: 133 GWKLYDPL 140
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 31.6 bits (70), Expect = 0.98
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 161 GEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIEL--FNQGTAFPAF 218
GE SY L++V K+ L +P+G R IF + V + + L F FP
Sbjct: 73 GENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN 132
Query: 219 EMEAYRPV 226
+ Y P+
Sbjct: 133 GWKLYDPL 140
>gi|139394604 bromo adjacent homology domain containing 1 [Homo
sapiens]
Length = 780
Score = 31.2 bits (69), Expect = 1.3
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 218 FEMEAYRPVGVVDFPRTEAGHLAGTVHPQL 247
F E R +G ++FP EAGH A HP L
Sbjct: 475 FAAEGCRSLGQLEFPLPEAGHPASPAHPLL 504
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 30.8 bits (68), Expect = 1.7
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 24/97 (24%)
Query: 84 PDDPYEVTRARE----------------LNQLLGPKASGQAFDF------VLDLHNTTAN 121
P +P E T A E + +LLG K Q F F +L L T
Sbjct: 428 PSEPVEWTGAEESLFRVFHGTYFNNFCSIARLLGTKTCKQVFQFAVKESLILKLP-TDEL 486
Query: 122 MGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQ 158
M K H ++A H CR +QL+ S QV+ YQ
Sbjct: 487 MNPSQKKKRKHRLWAAH-CRKIQLKKDNSSTQVYNYQ 522
>gi|20302168 toll-like receptor 8 [Homo sapiens]
Length = 1041
Score = 30.4 bits (67), Expect = 2.2
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 17/75 (22%)
Query: 238 HLAGTVHPQLQDRDFQPL-----------------QPGAPIFQMFSGEDLLYEGESTVYP 280
HL G V +L++ DFQPL Q +FQ FS +++Y E+ + P
Sbjct: 373 HLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISP 432
Query: 281 VFINEAAYYEKGVAF 295
+ + Y +F
Sbjct: 433 LVKDTRQSYANSSSF 447
>gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [Homo
sapiens]
Length = 2799
Score = 29.6 bits (65), Expect = 3.7
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 9 EPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSGCRRYVD-H 67
EPL R T +H N + + W + QRA+ +A + PAA+S Y+D
Sbjct: 1693 EPLERT--TNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPS 1750
Query: 68 DLNRTFTSS 76
+L R+ T S
Sbjct: 1751 NLRRSGTIS 1759
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 28.9 bits (63), Expect = 6.3
Identities = 12/49 (24%), Positives = 27/49 (55%)
Query: 123 GTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVA 171
G CL+A+ + ++ C+H+ L P+L+ + ++ G + +L S +
Sbjct: 533 GDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSAS 581
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 28.9 bits (63), Expect = 6.3
Identities = 12/49 (24%), Positives = 27/49 (55%)
Query: 123 GTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVA 171
G CL+A+ + ++ C+H+ L P+L+ + ++ G + +L S +
Sbjct: 533 GDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSAS 581
>gi|239756555 PREDICTED: hypothetical protein XP_002344930 [Homo
sapiens]
Length = 345
Score = 28.5 bits (62), Expect = 8.3
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 41 LQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLL 100
L SFS P A+PAA + C R + + R ++ + +R + P RE N
Sbjct: 120 LVAGSFS--PPRASPAAAASCARQNESESVRVGFAAAILARASDSAPLLAADPRERNWKT 177
Query: 101 GPKASGQAFDFVLDLHNTTANM--GTC 125
G K+SG A L L + TA M G+C
Sbjct: 178 G-KSSGTA---SLTLFSATAVMQVGSC 200
>gi|239751056 PREDICTED: hypothetical protein [Homo sapiens]
Length = 345
Score = 28.5 bits (62), Expect = 8.3
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 41 LQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLL 100
L SFS P A+PAA + C R + + R ++ + +R + P RE N
Sbjct: 120 LVAGSFS--PPRASPAAAASCARQNESESVRVGFAAAILARASDSAPLLAADPRERNWKT 177
Query: 101 GPKASGQAFDFVLDLHNTTANM--GTC 125
G K+SG A L L + TA M G+C
Sbjct: 178 G-KSSGTA---SLTLFSATAVMQVGSC 200
>gi|239745519 PREDICTED: hypothetical protein XP_002343478 [Homo
sapiens]
Length = 345
Score = 28.5 bits (62), Expect = 8.3
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 41 LQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLL 100
L SFS P A+PAA + C R + + R ++ + +R + P RE N
Sbjct: 120 LVAGSFS--PPRASPAAAASCARQNESESVRVGFAAAILARASDSAPLLAADPRERNWKT 177
Query: 101 GPKASGQAFDFVLDLHNTTANM--GTC 125
G K+SG A L L + TA M G+C
Sbjct: 178 G-KSSGTA---SLTLFSATAVMQVGSC 200
>gi|27881501 ATP-binding cassette, sub-family A, member 12 isoform b
[Homo sapiens]
Length = 2277
Score = 28.5 bits (62), Expect = 8.3
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 9/76 (11%)
Query: 68 DLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAF----DFVLDLHNTTANMG 123
+LN F + S P+ + T L L G A G F D DLH NMG
Sbjct: 1045 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASA-GTIFVYGKDIKTDLHTVRKNMG 1103
Query: 124 TCLIAKSSHEVFAMHL 139
C+ H+V +L
Sbjct: 1104 VCM----QHDVLFSYL 1115
>gi|30795238 ATP-binding cassette, sub-family A, member 12 isoform a
[Homo sapiens]
Length = 2595
Score = 28.5 bits (62), Expect = 8.3
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 9/76 (11%)
Query: 68 DLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAF----DFVLDLHNTTANMG 123
+LN F + S P+ + T L L G A G F D DLH NMG
Sbjct: 1363 NLNLNFYEGHITSLLGPNGAGKTTTISMLTGLFGASA-GTIFVYGKDIKTDLHTVRKNMG 1421
Query: 124 TCLIAKSSHEVFAMHL 139
C+ H+V +L
Sbjct: 1422 VCM----QHDVLFSYL 1433
>gi|4757956 cadherin 16 precursor [Homo sapiens]
Length = 829
Score = 28.5 bits (62), Expect = 8.3
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 29/133 (21%)
Query: 37 APAELQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRAREL 96
APA+ F P L A + +DH L RT+ + + +++
Sbjct: 171 APAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQL--------------LVQVKDM 216
Query: 97 NQLLGPKASGQAFDFVLDLHNTTANMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFL 156
G +ASG H TA + +I + + +HL +L++ YP QV
Sbjct: 217 ----GDQASG---------HQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQV-- 261
Query: 157 YQRSGEESYNLDS 169
+ G+ Y+L+S
Sbjct: 262 HWSGGDVHYHLES 274
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,227,298
Number of Sequences: 37866
Number of extensions: 605577
Number of successful extensions: 1252
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1241
Number of HSP's gapped (non-prelim): 19
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.