Guide to the Human Genome
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Search of human proteins with 170784863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170784863 hedgehog acyltransferase [Homo sapiens]
         (493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170784861 hedgehog acyltransferase [Homo sapiens]                 1042   0.0  
gi|170784863 hedgehog acyltransferase [Homo sapiens]                 1042   0.0  
gi|239582769 hedgehog acyltransferase-like [Homo sapiens]             182   6e-46
gi|30102940 otopetrin 3 [Homo sapiens]                                 33   0.59 
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    30   3.8  
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         30   3.8  
gi|19923957 major facilitator superfamily domain containing 3 [H...    30   3.8  
gi|116686114 kindlin-1 [Homo sapiens]                                  30   5.0  
gi|4506979 solute carrier family 13, member 2 isoform b [Homo sa...    30   6.6  
gi|225637549 solute carrier family 13, member 2 isoform a [Homo ...    30   6.6  
gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]          30   6.6  
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]       29   8.6  

>gi|170784861 hedgehog acyltransferase [Homo sapiens]
          Length = 493

 Score = 1042 bits (2695), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW 60
           MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW
Sbjct: 1   MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW 60

Query: 61  SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH 120
           SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH
Sbjct: 61  SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH 120

Query: 121 TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY 180
           TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY
Sbjct: 121 TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY 180

Query: 181 TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS 240
           TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS
Sbjct: 181 TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS 240

Query: 241 LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY 300
           LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY
Sbjct: 241 LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY 300

Query: 301 LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG 360
           LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG
Sbjct: 301 LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG 360

Query: 361 LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS 420
           LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS
Sbjct: 361 LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS 420

Query: 421 PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS 480
           PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS
Sbjct: 421 PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS 480

Query: 481 HVGIAWAQTYATD 493
           HVGIAWAQTYATD
Sbjct: 481 HVGIAWAQTYATD 493


>gi|170784863 hedgehog acyltransferase [Homo sapiens]
          Length = 493

 Score = 1042 bits (2695), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW 60
           MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW
Sbjct: 1   MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEW 60

Query: 61  SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH 120
           SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH
Sbjct: 61  SFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLH 120

Query: 121 TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY 180
           TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY
Sbjct: 121 TTISFCVAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYY 180

Query: 181 TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS 240
           TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS
Sbjct: 181 TSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKAS 240

Query: 241 LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY 300
           LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY
Sbjct: 241 LCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY 300

Query: 301 LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG 360
           LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG
Sbjct: 301 LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG 360

Query: 361 LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS 420
           LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS
Sbjct: 361 LLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFS 420

Query: 421 PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS 480
           PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS
Sbjct: 421 PQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYS 480

Query: 481 HVGIAWAQTYATD 493
           HVGIAWAQTYATD
Sbjct: 481 HVGIAWAQTYATD 493


>gi|239582769 hedgehog acyltransferase-like [Homo sapiens]
          Length = 504

 Score =  182 bits (462), Expect = 6e-46
 Identities = 139/487 (28%), Positives = 225/487 (46%), Gaps = 25/487 (5%)

Query: 2   LPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWS 61
           LP  EL LY L   G   Y+   + + S++          +     + G K D  DFEW 
Sbjct: 7   LPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWV 66

Query: 62  FWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHT 121
            W    +  +++ L GH++ +++ T++A K R W+  +YG  A   V+GT G   +LL  
Sbjct: 67  MWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALA---VMGTMGPWYLLL-- 121

Query: 122 TISFCVAQFRSQLL--TWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTL------ 173
            +  CV  + + LL   WLC  L L++L    ++ +           + LQ  L      
Sbjct: 122 LLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSS 181

Query: 174 --TVRCLYYTSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQ 231
              +RC   TSF+LE C          YS   +L Y FY P    GPI++F  F  Q+ Q
Sbjct: 182 FTVLRC---TSFALESCAHP----DRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQ 234

Query: 232 QEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALA 291
            E    +  L  +    G  +      ++  H  Y+  I S +     +    L GLA +
Sbjct: 235 VEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYS 294

Query: 292 QVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVY 351
            +++ +VK  VLFGV   +  LD L PP  P+C++ ++ F     +FD G++++L +YVY
Sbjct: 295 NLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAET--HFDRGINDWLCKYVY 352

Query: 352 IPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCI 411
             +GG    ++  L +T  TFA  + W G  D ++ W+ LN  G+  E  +++L E   +
Sbjct: 353 NHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPL 412

Query: 412 QDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLS 471
              +    S Q  RR  A   + +   +I+ NLV L   +  +    R+ + G+P  TLS
Sbjct: 413 A-RIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLS 471

Query: 472 VLGFLYC 478
           +L   YC
Sbjct: 472 ILFVTYC 478


>gi|30102940 otopetrin 3 [Homo sapiens]
          Length = 596

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 4/81 (4%)

Query: 415 LARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQ-GWPWV---TL 470
           L R+FS   RR   A  A    S L+  N+VFLGG  +    +N++ +  G  W+   TL
Sbjct: 69  LVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDVWILLATL 128

Query: 471 SVLGFLYCYSHVGIAWAQTYA 491
            VL  L+   +V     + +A
Sbjct: 129 KVLSLLWLLYYVASTTRRPHA 149


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 8/79 (10%)

Query: 331 FTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTL-FSTAMTFAFVSYWHGGYD-YLWCW 388
           FTG    F++  + ++ RY++      +   LG    S  ++  F++ WHG +  YL C+
Sbjct: 330 FTGTIASFNINTNAWVARYIF-----KRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCF 384

Query: 389 AALNWLGVTVENGVRRLVE 407
             + +L V VE    RL++
Sbjct: 385 -QMEFLIVIVERQAARLIQ 402


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 42/189 (22%), Positives = 78/189 (41%), Gaps = 35/189 (18%)

Query: 248 LGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGVP 307
           LG ++  +W A+++  ++    ++S++ L   + C+++       + F+ V++L + G  
Sbjct: 226 LGSIIFGYWCAKIIQCILA--DVFSNM-LTNIILCFSM-----VYMTFYIVEFLGMSGTL 277

Query: 308 ALL---MRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHG---- 360
           AL    + LD LT       V T F      R F     + +  +  I +G  +      
Sbjct: 278 ALAAVGLNLDSLTFKPKIELVITKFL-----RIFSSVYEHLIYAFFGIVIGCGELSHYEF 332

Query: 361 ----LLGTLFSTA-----MTFAFVS--YWHGGYDYLWCW-AALNWLGVTVENGVRRLVET 408
                +  LF+T      +T   VS    H  Y+Y W W   + W G+    GV  L+  
Sbjct: 333 HTIPFIFILFTTVNLVRLLTILLVSPILMHSNYEYNWRWGVVITWSGI---KGVFNLLWA 389

Query: 409 PCIQDSLAR 417
           P + +   R
Sbjct: 390 PDVYNLAER 398


>gi|19923957 major facilitator superfamily domain containing 3 [Homo
           sapiens]
          Length = 412

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 247 GLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKYLVLFGV 306
           G+G ++C    + L   L+  H  +  +PLL +V  + LGGLA    L F++  L     
Sbjct: 255 GVGAVVCSIAGSSLGGTLLAKH--WKLLPLLRSVLRFRLGGLACQTALVFHLDTLGASMD 312

Query: 307 PALLMRLDGLTPPALPRCVS---TMFSFTGMWR 336
              ++R   L    L   +    T  +FTGM R
Sbjct: 313 AGTILRGSALLSLCLQHFLGGLVTTVTFTGMMR 345


>gi|116686114 kindlin-1 [Homo sapiens]
          Length = 677

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 32/146 (21%)

Query: 11  LLASLGFHFYSFYEVYKVSREHEEEL-DQEFELETDTLFGGLKKDATDF-----EWSFWM 64
           +L+S  F F S+  V +V   +EE+  D    +  D   GG+     +      +WS + 
Sbjct: 1   MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFA 60

Query: 65  EWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMV------- 117
            W +Q   WLL  H                W L  YG+ A   +L TP   M+       
Sbjct: 61  LWWEQKHCWLLKTH----------------WTLDKYGVQADAKLLFTPQHKMLRLRLPNL 104

Query: 118 -LLHTTISFCVAQFRSQLLTWLCSLL 142
            ++   +SF    F++  ++ +C +L
Sbjct: 105 KMVRLRVSFSAVVFKA--VSDICKIL 128


>gi|4506979 solute carrier family 13, member 2 isoform b [Homo
           sapiens]
          Length = 592

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 8/55 (14%)

Query: 281 SCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMW 335
           +CW        Q L+ Y  YL++F VP LL+ L  L P     C   +      W
Sbjct: 3   TCW--------QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFW 49


>gi|225637549 solute carrier family 13, member 2 isoform a [Homo
           sapiens]
          Length = 641

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 8/55 (14%)

Query: 281 SCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMW 335
           +CW        Q L+ Y  YL++F VP LL+ L  L P     C   +      W
Sbjct: 3   TCW--------QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFW 49


>gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]
          Length = 307

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 12/27 (44%), Positives = 19/27 (70%), Gaps = 1/27 (3%)

Query: 63  WMEWG-KQWLVWLLLGHMVVSQMATLL 88
           W++W    W+ WLLLG +++S + TLL
Sbjct: 121 WLKWRFPGWVPWLLLGSVLISFIITLL 147


>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
          Length = 1136

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 15/34 (44%), Positives = 18/34 (52%)

Query: 264 LMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFY 297
           L  MH I S  PLL TV   T  G  +A+V  F+
Sbjct: 158 LRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFH 191


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.140    0.484 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,488,276
Number of Sequences: 37866
Number of extensions: 787440
Number of successful extensions: 2182
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2167
Number of HSP's gapped (non-prelim): 13
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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