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Search of human proteins with 170296790
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
(304 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 644 0.0
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 492 e-139
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 442 e-124
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 432 e-121
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 218 4e-57
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 214 8e-56
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 209 2e-54
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 209 2e-54
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 209 2e-54
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 207 1e-53
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 204 1e-52
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 204 1e-52
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 204 1e-52
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 202 4e-52
gi|11496281 kallikrein 13 precursor [Homo sapiens] 200 1e-51
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 199 2e-51
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 199 2e-51
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 198 4e-51
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 198 4e-51
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 194 6e-50
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 192 4e-49
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 192 4e-49
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 189 2e-48
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 187 8e-48
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 179 3e-45
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 179 3e-45
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 179 3e-45
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 177 1e-44
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 177 1e-44
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 174 7e-44
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 644 bits (1660), Expect = 0.0
Identities = 304/304 (100%), Positives = 304/304 (100%)
Query: 1 MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAAR 60
MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAAR
Sbjct: 1 MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAAR 60
Query: 61 DADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAH 120
DADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAH
Sbjct: 61 DADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAH 120
Query: 121 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 180
CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV
Sbjct: 121 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 180
Query: 181 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 240
STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM
Sbjct: 181 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 240
Query: 241 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 300
FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI
Sbjct: 241 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 300
Query: 301 AANS 304
AANS
Sbjct: 301 AANS 304
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 492 bits (1267), Expect = e-139
Identities = 234/234 (100%), Positives = 234/234 (100%)
Query: 71 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 130
VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL
Sbjct: 14 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 73
Query: 131 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 190
GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP
Sbjct: 74 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 133
Query: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK
Sbjct: 134 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 193
Query: 251 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS
Sbjct: 194 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 442 bits (1138), Expect = e-124
Identities = 210/234 (89%), Positives = 222/234 (94%)
Query: 71 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 130
VA PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLISEQWVVSA HCYK+RIQVRL
Sbjct: 14 VAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRL 73
Query: 131 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 190
GEHNI+VLEGNEQFINAAKIIRHPKYN TLDNDI+LIKLSSPAVIN+RVS ISLPTAPP
Sbjct: 74 GEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPP 133
Query: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
AAGTE LISGWGNTLS GADYPDEL+CLDAPVL+QAEC+ASYPGKITN+MFCVGFLEGGK
Sbjct: 134 AAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGK 193
Query: 251 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
DSCQ DSGGPVV NG+LQG+VSWG+GCA KNRPGVYTKVYNYVDWIKDTIAANS
Sbjct: 194 DSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 432 bits (1112), Expect = e-121
Identities = 204/234 (87%), Positives = 221/234 (94%)
Query: 71 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 130
+A PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLI+EQWVVSA HCYK+RIQVRL
Sbjct: 14 LAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRL 73
Query: 131 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 190
GEHNI+VLEGNEQFINAAKIIRHP+Y+R TL+NDIMLIKLSS AVINARVSTISLPTAPP
Sbjct: 74 GEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPP 133
Query: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
A GT+CLISGWGNT S GADYPDEL+CLDAPVL+QA+C+ASYPGKIT++MFCVGFLEGGK
Sbjct: 134 ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGK 193
Query: 251 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
DSCQ DSGGPVVCNGQLQGVVSWG GCA KN+PGVYTKVYNYV WIK+TIAANS
Sbjct: 194 DSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 247
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 218 bits (556), Expect = 4e-57
Identities = 112/260 (43%), Positives = 157/260 (60%), Gaps = 9/260 (3%)
Query: 50 LLGGRTWRAARDADGC-EALGTVAVPF----DDDDKIVGGYTCEENSLPYQVSLNSGSH- 103
+LG TW +A AL +A+ +D++KI+GG+TC +S P+Q +L +G
Sbjct: 5 VLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRR 64
Query: 104 --FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL 161
CGG+L+S QWV++AAHC + +QV LG+HN++ E +Q + + + HP YN T
Sbjct: 65 RFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTH 124
Query: 162 DNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAP 221
DND+ML++L PA I V I + A + GT C +SGWG S A YP L+C++
Sbjct: 125 DNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNIN 184
Query: 222 VLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWK 280
+ C+ +YP IT M C G +GGKDSCQ DSGGP+VC GQLQG+VSWG CA
Sbjct: 185 ISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALP 244
Query: 281 NRPGVYTKVYNYVDWIKDTI 300
PGVYT + Y WI++T+
Sbjct: 245 GYPGVYTNLCKYRSWIEETM 264
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 214 bits (545), Expect = 8e-56
Identities = 110/250 (44%), Positives = 152/250 (60%), Gaps = 15/250 (6%)
Query: 69 GTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQ 127
GT A P +IVGG+ CE++S P+Q +L S F CGG L+ QWV++AAHC Q
Sbjct: 14 GTGAAP-PIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQ 72
Query: 128 VRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIKLSSPA-V 175
+ LG HN+ E QF++ ++ HP +N L+N D+ML++L+ PA
Sbjct: 73 LWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADT 132
Query: 176 INARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGK 235
I V + LPT P G+ CL SGWG+ +PD+L+C+D +L ECK ++ K
Sbjct: 133 ITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQK 192
Query: 236 ITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVD 294
+T+ M CVG LEGGKD+C DSGGP++C+G LQGV SWG+ C N+P V +V +YV
Sbjct: 193 VTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVK 252
Query: 295 WIKDTIAANS 304
WI+DTIA NS
Sbjct: 253 WIEDTIAENS 262
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 209 bits (533), Expect = 2e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 137 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 192
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 253 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 209 bits (533), Expect = 2e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 51 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
Query: 137 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 192
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
Query: 253 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 209 bits (533), Expect = 2e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 137 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 192
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 253 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 207 bits (526), Expect = 1e-53
Identities = 103/239 (43%), Positives = 144/239 (60%), Gaps = 12/239 (5%)
Query: 77 DDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 135
D DK++ G C +S P+QV+L F CG SLIS WV+SAAHC ++VRLGEHN+
Sbjct: 18 DGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNL 77
Query: 136 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTE 195
+ +G EQ +++I HP+Y + NDIML++L PA +N +V LPT P G
Sbjct: 78 RKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEA 137
Query: 196 CLISGWG----------NTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGF 245
C++SGWG + PD L C + +++ C SYPG++TN+M C G
Sbjct: 138 CVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGA 197
Query: 246 LEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
G +SC+ DSGGP+VC G LQG+VSWG C +PGVYTKV +Y++WI++T+ N
Sbjct: 198 EGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 1e-52
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 76 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 133
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 134 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 192
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 253 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 1e-52
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 76 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 133
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 134 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 192
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 253 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 1e-52
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 76 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 133
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 134 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 192
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 253 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 202 bits (513), Expect = 4e-52
Identities = 111/247 (44%), Positives = 141/247 (57%), Gaps = 14/247 (5%)
Query: 70 TVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQV 128
T AVP +IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K QV
Sbjct: 15 TGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQV 73
Query: 129 RLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVIN 177
LG HN+ E Q + + HP YN L +D+ML++LS PA I
Sbjct: 74 WLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT 133
Query: 178 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 237
V + LPT PA GT C SGWG+ P L+C+ +L+ C +Y K+T
Sbjct: 134 DVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 193
Query: 238 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWI 296
M C G GGKD+C DSGGP+VCNG LQG+ SWG CA +P VYTKV +Y WI
Sbjct: 194 EFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWI 253
Query: 297 KDTIAAN 303
KDTIAAN
Sbjct: 254 KDTIAAN 260
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 200 bits (508), Expect = 1e-51
Identities = 102/225 (45%), Positives = 137/225 (60%), Gaps = 7/225 (3%)
Query: 83 GGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGN 141
GGYTC +S P+Q +L G CGG L+ +WV++AAHC K ++V LG+H + +E
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 142 EQFINAAKIIRHPKYNRDTL----DNDIMLIKLSSPAVINARVSTISLP-TAPPAAGTEC 196
EQ I HP+Y R D+DIML++L SP + + T+ L GT C
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 197 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 256
+SGWG T S +YP L+C + + + EC+ YPGKIT++M C G EGGKDSC+ D
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 257 SGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300
SGGP+VCN L G+VSWG C +RPGVYT+V YV WI++TI
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
Query: 137 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 193
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
Query: 194 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 253
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
Query: 254 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 302
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
Query: 137 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 193
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
Query: 194 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 253
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
Query: 254 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 302
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 198 bits (504), Expect = 4e-51
Identities = 96/229 (41%), Positives = 144/229 (62%), Gaps = 4/229 (1%)
Query: 76 DDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHN 134
++ +K+V G C++ S PYQ +L + H CGG LI WV++AAHC K +QV LG+HN
Sbjct: 17 EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHN 76
Query: 135 IKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGT 194
++ E +++ + + + HP Y+ + D DIML++L+ PA ++ + + L A T
Sbjct: 77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTT 136
Query: 195 ECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQ 254
C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M C G + GKDSCQ
Sbjct: 137 SCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQ 194
Query: 255 RDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAA 302
DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ TI A
Sbjct: 195 GDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 198 bits (504), Expect = 4e-51
Identities = 96/229 (41%), Positives = 144/229 (62%), Gaps = 4/229 (1%)
Query: 76 DDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHN 134
++ +K+V G C++ S PYQ +L + H CGG LI WV++AAHC K +QV LG+HN
Sbjct: 17 EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHN 76
Query: 135 IKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGT 194
++ E +++ + + + HP Y+ + D DIML++L+ PA ++ + + L A T
Sbjct: 77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTT 136
Query: 195 ECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQ 254
C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M C G + GKDSCQ
Sbjct: 137 SCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQ 194
Query: 255 RDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAA 302
DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ TI A
Sbjct: 195 GDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 194 bits (494), Expect = 6e-50
Identities = 101/237 (42%), Positives = 135/237 (56%), Gaps = 13/237 (5%)
Query: 80 KIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
+IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++
Sbjct: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
Query: 139 EGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIKLSSPAVINARVSTISLPT 187
E Q + HP Y+ L N D+ML++LS PA + V + LPT
Sbjct: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
Query: 188 APPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLE 247
PA GT C SGWG+ P +L+C+D V++ C +P K+T M C G
Sbjct: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
Query: 248 GGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN
Sbjct: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 192 bits (487), Expect = 4e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 79 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 137
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
Query: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
Query: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
Query: 258 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 192 bits (487), Expect = 4e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 79 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 137
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
Query: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
Query: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
Query: 258 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 189 bits (481), Expect = 2e-48
Identities = 102/240 (42%), Positives = 139/240 (57%), Gaps = 6/240 (2%)
Query: 65 CEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAAHCYK 123
C L +A D + +G C NS P+Q L + FCG +LIS++W+++AAHC K
Sbjct: 7 CALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRK 66
Query: 124 TRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDND----IMLIKLSSPAVINAR 179
+ VRLGEH++ EG EQ HP +N+D ND IMLI+L A ++
Sbjct: 67 PYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPA 126
Query: 180 VSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNS 239
V ++L + G +CLISGWG S A +P L+C + +L C +YPG I++S
Sbjct: 127 VQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDS 186
Query: 240 MFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKD 298
M C G EGG+ SCQ DSGGP+VCNG L GVVS G C+ RP VYT V +Y+DWI++
Sbjct: 187 MLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 187 bits (476), Expect = 8e-48
Identities = 97/223 (43%), Positives = 135/223 (60%), Gaps = 6/223 (2%)
Query: 80 KIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
KI G C NS P+QV L G+ CGG LI +WV++AAHC +R VRLGEH++ L
Sbjct: 21 KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQL 80
Query: 139 EGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTEC 196
+ EQ ++ + HP Y + ++D+ L++L P + + V + LP AGTEC
Sbjct: 81 DWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTEC 140
Query: 197 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 256
+SGWG T +PD L+CL+ +++ A C YPG+IT++M C G + G+D+CQ D
Sbjct: 141 HVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGD 199
Query: 257 SGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYNYVDWIK 297
SGGP+VC G LQG+VSWG C PGVYT + YVDWI+
Sbjct: 200 SGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIR 242
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 3e-45
Identities = 99/270 (36%), Positives = 146/270 (54%), Gaps = 24/270 (8%)
Query: 46 ELHPLLGGRTWRAARDADGCEALGTVAVPFDDD--DKIVGGYTCEENSLPYQVSLNSGSH 103
+L PLL + W A +P +D D G C S P+QVSL +G
Sbjct: 19 KLLPLLMAQLWAAE----------AALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLS 68
Query: 104 F-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN----- 157
F C G L+ + WV++AAHC + R+G+ ++ +L+G EQ + + HPKY+
Sbjct: 69 FHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGP 127
Query: 158 ---RDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDE 214
R T ++D+ML+KL+ P V+ RV + LP G +C ++GWG T + Y
Sbjct: 128 ILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKG 187
Query: 215 LKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG 274
L C +L+ EC+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG
Sbjct: 188 LTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWG 246
Query: 275 -HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
+ C P VYT++ Y+ WI I +N
Sbjct: 247 VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 3e-45
Identities = 99/270 (36%), Positives = 146/270 (54%), Gaps = 24/270 (8%)
Query: 46 ELHPLLGGRTWRAARDADGCEALGTVAVPFDDD--DKIVGGYTCEENSLPYQVSLNSGSH 103
+L PLL + W A +P +D D G C S P+QVSL +G
Sbjct: 19 KLLPLLMAQLWAAE----------AALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLS 68
Query: 104 F-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN----- 157
F C G L+ + WV++AAHC + R+G+ ++ +L+G EQ + + HPKY+
Sbjct: 69 FHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGP 127
Query: 158 ---RDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDE 214
R T ++D+ML+KL+ P V+ RV + LP G +C ++GWG T + Y
Sbjct: 128 ILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKG 187
Query: 215 LKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG 274
L C +L+ EC+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG
Sbjct: 188 LTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWG 246
Query: 275 -HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
+ C P VYT++ Y+ WI I +N
Sbjct: 247 VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 3e-45
Identities = 99/270 (36%), Positives = 146/270 (54%), Gaps = 24/270 (8%)
Query: 46 ELHPLLGGRTWRAARDADGCEALGTVAVPFDDD--DKIVGGYTCEENSLPYQVSLNSGSH 103
+L PLL + W A +P +D D G C S P+QVSL +G
Sbjct: 19 KLLPLLMAQLWAAE----------AALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLS 68
Query: 104 F-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN----- 157
F C G L+ + WV++AAHC + R+G+ ++ +L+G EQ + + HPKY+
Sbjct: 69 FHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGP 127
Query: 158 ---RDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDE 214
R T ++D+ML+KL+ P V+ RV + LP G +C ++GWG T + Y
Sbjct: 128 ILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKG 187
Query: 215 LKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG 274
L C +L+ EC+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG
Sbjct: 188 LTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWG 246
Query: 275 -HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
+ C P VYT++ Y+ WI I +N
Sbjct: 247 VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 177 bits (449), Expect = 1e-44
Identities = 88/235 (37%), Positives = 134/235 (57%), Gaps = 12/235 (5%)
Query: 80 KIVGGYTCEENSLPYQVSLNSGS-HFCGGSLISEQWVVSAAHCYK----TRIQVRLGEHN 134
++VGG+ +P+QVSL GS HFCG +++ ++W++SAAHC+ +++ LG +
Sbjct: 503 RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTAS 562
Query: 135 IKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA--A 192
+ L G+ I +++ HP YN LD D+ +++L+SP N + + LP A
Sbjct: 563 LLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPV 622
Query: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252
G +C+ISGWGNT A P+ L+ ++ Q C Y +T+ M C GFLEG DS
Sbjct: 623 GRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDS 682
Query: 253 CQRDSGGPVVCNG-----QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAA 302
CQ DSGGP+ C L G+VSWG GCA +PGVYT++ WI + +++
Sbjct: 683 CQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS 737
Score = 162 bits (409), Expect = 4e-40
Identities = 89/232 (38%), Positives = 124/232 (53%), Gaps = 17/232 (7%)
Query: 80 KIVGGYTCEENSLPYQVSLNSGS-HFCGGSLISEQWVVSAAHCYK-----TRIQVRLGEH 133
+IVGG P+Q SL HFCG ++I+ +W+VSAAHC+ T+ +G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGAT 261
Query: 134 NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA----P 189
+ E + +I++HP YN DT D D+ +++L+SP + + LP A P
Sbjct: 262 YLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFP 321
Query: 190 PAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGG 249
P+ +CLISGWG P+ L+ +L QA C + Y +T+ M C G+L+G
Sbjct: 322 PSK--KCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGK 379
Query: 250 KDSCQRDSGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 296
DSCQ DSGGP+VC L G+VSWG GCA RPGVY +V DWI
Sbjct: 380 VDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431
Score = 148 bits (374), Expect = 5e-36
Identities = 89/231 (38%), Positives = 124/231 (53%), Gaps = 17/231 (7%)
Query: 80 KIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVR-----LGE 132
+IVGG P+QVSL H CG L++E+W++SAAHC+ + LG
Sbjct: 826 RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885
Query: 133 HNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT-AP-P 190
+ EG Q A+I +HP YN TLD D+ L++L+ P + V I LP AP P
Sbjct: 886 PFLSGAEG--QLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRP 943
Query: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
GT C+I+GWG+ G +L+ +L++ C+ YP +I++ M C GF +GG
Sbjct: 944 PDGTRCVITGWGSVRE-GGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGV 1002
Query: 251 DSCQRDSGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 296
DSC D+GGP+ C L GV SWG+GC + PGVYT+V WI
Sbjct: 1003 DSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 177 bits (448), Expect = 1e-44
Identities = 93/217 (42%), Positives = 130/217 (59%), Gaps = 6/217 (2%)
Query: 80 KIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
KI G C NS P+QV L G+ CGG LI +WV++AAHC +R VRLGEH++ L
Sbjct: 21 KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQL 80
Query: 139 EGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTEC 196
+ EQ ++ + HP Y + ++D+ L++L P + + V + LP AGTEC
Sbjct: 81 DWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTEC 140
Query: 197 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 256
+SGWG T +PD L+CL+ +++ A C YPG+IT++M C G + G+D+CQ D
Sbjct: 141 HVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGD 199
Query: 257 SGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYN 291
SGGP+VC G LQG+VSWG C PGVYT + N
Sbjct: 200 SGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICN 236
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 174 bits (442), Expect = 7e-44
Identities = 90/227 (39%), Positives = 131/227 (57%), Gaps = 5/227 (2%)
Query: 80 KIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV- 137
+I+ G C +S P+Q +L + FC G L+ QWV+SAAHC++ + LG H+++
Sbjct: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
Query: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197
E Q + A+ +RHP+YNR L ND+MLIKL + + +IS+ + P AG CL
Sbjct: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149
Query: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257
+SGWG L P L+C++ V+++ C Y SMFC G KDSC DS
Sbjct: 150 VSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207
Query: 258 GGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303
GGP++CNG LQG+VS+G C PGVYT + + +WI+ T+ A+
Sbjct: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,914,339
Number of Sequences: 37866
Number of extensions: 686123
Number of successful extensions: 2393
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1655
Number of HSP's gapped (non-prelim): 211
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.