Guide to the Human Genome
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Search of human proteins with 169217946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169217946 PREDICTED: similar to PML protein [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169217946 PREDICTED: similar to PML protein [Homo sapiens]         584   e-167
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]   509   e-144
gi|187960059 syndecan 3 [Homo sapiens]                                 31   1.5  
gi|239756547 PREDICTED: hypothetical protein [Homo sapiens]            28   7.5  
gi|169210434 PREDICTED: hypothetical protein [Homo sapiens]            28   7.5  
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                28   9.8  

>gi|169217946 PREDICTED: similar to PML protein [Homo sapiens]
          Length = 298

 Score =  584 bits (1506), Expect = e-167
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MGWRAKFKQPGISRSELHLGADVWLLPADPKVRSLDAQKISQLAAVNRESKFRVVIQPEA 60
           MGWRAKFKQPGISRSELHLGADVWLLPADPKVRSLDAQKISQLAAVNRESKFRVVIQPEA
Sbjct: 1   MGWRAKFKQPGISRSELHLGADVWLLPADPKVRSLDAQKISQLAAVNRESKFRVVIQPEA 60

Query: 61  FFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAI 120
           FFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAI
Sbjct: 61  FFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAI 120

Query: 121 SGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQ 180
           SGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQ
Sbjct: 121 SGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQ 180

Query: 181 LAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYS 240
           LAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYS
Sbjct: 181 LAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYS 240

Query: 241 RYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS 298
           RYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS
Sbjct: 241 RYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS 298


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score =  509 bits (1310), Expect = e-144
 Identities = 261/263 (99%), Positives = 262/263 (99%)

Query: 36  DAQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKL 95
           + QKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKL
Sbjct: 620 ETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKL 679

Query: 96  WGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMS 155
           WGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMS
Sbjct: 680 WGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMS 739

Query: 156 ERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLA 215
           ERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLA
Sbjct: 740 ERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLA 799

Query: 216 LHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPAL 275
           LHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPAL
Sbjct: 800 LHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPAL 859

Query: 276 ARAEGVSTPLAGRGLAERASQQS 298
           ARAEGVSTPLAGRGLAERASQQS
Sbjct: 860 ARAEGVSTPLAGRGLAERASQQS 882


>gi|187960059 syndecan 3 [Homo sapiens]
          Length = 442

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 4/62 (6%)

Query: 238 KYSRYLSLQTTTLPPAQPAFNLQALGTYFEGL-LEGPALARAEGVSTPLAGRGLAERASQ 296
           ++S  ++L  +T P   P  N+Q +GT FE L  E P L   E  ++PL    + E  SQ
Sbjct: 98  RFSPDVALAVSTTPAVLPTTNIQPVGTPFEELPSERPTL---EPATSPLVVTEVPEEPSQ 154

Query: 297 QS 298
           ++
Sbjct: 155 RA 156


>gi|239756547 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 240

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 9/48 (18%)

Query: 224 LLSAHRRDRQGGLKKYSRYLSLQTTT---------LPPAQPAFNLQAL 262
           LL A+RR R  GL K +  +S  TTT         L PA+P F+ + +
Sbjct: 191 LLPANRRCRSRGLTKMAAAVSAATTTTTTTTRSESLSPARPVFSRETI 238


>gi|169210434 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 301

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 9/48 (18%)

Query: 224 LLSAHRRDRQGGLKKYSRYLSLQTTT---------LPPAQPAFNLQAL 262
           LL A+RR R  GL K +  +S  TTT         L PA+P F+ + +
Sbjct: 252 LLPANRRCRSRGLTKMAAAVSAATTTTTTTTRSESLSPARPVFSRETI 299


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 229  RRDRQGGLKKYSRYLSLQTTTLPPAQPAF 257
            R D QGG +++S      TTT+ P  P+F
Sbjct: 1137 RADPQGGRRRHSSETFSSTTTVTPVSPSF 1165


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,628,404
Number of Sequences: 37866
Number of extensions: 412048
Number of successful extensions: 940
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 937
Number of HSP's gapped (non-prelim): 6
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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