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Search of human proteins with 169171979
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo
sapiens]
(1492 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapi... 3115 0.0
gi|221316699 maltase-glucoamylase [Homo sapiens] 2506 0.0
gi|157364974 sucrase-isomaltase [Homo sapiens] 1645 0.0
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens] 625 e-179
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens] 625 e-179
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens] 625 e-179
gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens] 253 1e-66
gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens] 253 1e-66
gi|66346737 glucosidase, alpha; neutral C [Homo sapiens] 248 4e-65
gi|153791946 hypothetical protein LOC57462 [Homo sapiens] 69 3e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 32 6.0
gi|211058421 zinc finger protein 844 [Homo sapiens] 32 6.0
gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 31 7.8
>gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapiens]
Length = 1492
Score = 3115 bits (8076), Expect = 0.0
Identities = 1492/1492 (100%), Positives = 1492/1492 (100%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG 60
MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG
Sbjct: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG 60
Query: 61 FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRA 120
FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRA
Sbjct: 61 FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRA 120
Query: 121 YVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRD 180
YVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRD
Sbjct: 121 YVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRD 180
Query: 181 ASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQ 240
ASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQ
Sbjct: 181 ASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQ 240
Query: 241 EVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQTGADICGFFQ 300
EVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQTGADICGFFQ
Sbjct: 241 EVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQTGADICGFFQ 300
Query: 301 DAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLPYLYT 360
DAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLPYLYT
Sbjct: 301 DAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLPYLYT 360
Query: 361 LMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRAR 420
LMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRAR
Sbjct: 361 LMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRAR 420
Query: 421 WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLGLIIALD 480
WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLGLIIALD
Sbjct: 421 WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLGLIIALD 480
Query: 481 ENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAFNEIKIL 540
ENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAFNEIKIL
Sbjct: 481 ENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAFNEIKIL 540
Query: 541 GMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEEKID 600
GMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEEKID
Sbjct: 541 GMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEEKID 600
Query: 601 CYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSV 660
CYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSV
Sbjct: 601 CYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKSSV 660
Query: 661 HANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQLYDV 720
HANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQLYDV
Sbjct: 661 HANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQLYDV 720
Query: 721 LIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTSYRRD 780
LIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTSYRRD
Sbjct: 721 LIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTSYRRD 780
Query: 781 LEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTY 840
LEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTY
Sbjct: 781 LEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTY 840
Query: 841 RTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEISSLYDE 900
RTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEISSLYDE
Sbjct: 841 RTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEISSLYDE 900
Query: 901 MVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNET 960
MVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNET
Sbjct: 901 MVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNET 960
Query: 961 QPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDF 1020
QPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDF
Sbjct: 961 QPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDF 1020
Query: 1021 FRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPP 1080
FRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPP
Sbjct: 1021 FRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPP 1080
Query: 1081 YMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQEVTGQRG 1140
YMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQEVTGQRG
Sbjct: 1081 YMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQEVTGQRG 1140
Query: 1141 VVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEY 1200
VVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEY
Sbjct: 1141 VVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEY 1200
Query: 1201 EMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHK 1260
EMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHK
Sbjct: 1201 EMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLYTLMHK 1260
Query: 1261 AHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDY 1320
AHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDY
Sbjct: 1261 AHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDY 1320
Query: 1321 YTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGT 1380
YTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGT
Sbjct: 1321 YTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGT 1380
Query: 1381 AGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVG 1440
AGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVG
Sbjct: 1381 AGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVG 1440
Query: 1441 SVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL 1492
SVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL
Sbjct: 1441 SVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL 1492
>gi|221316699 maltase-glucoamylase [Homo sapiens]
Length = 1857
Score = 2506 bits (6495), Expect = 0.0
Identities = 1226/1498 (81%), Positives = 1307/1498 (87%), Gaps = 24/1498 (1%)
Query: 4 YWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTL-SPKFAGFP 62
YW+LGF L RY Y + + + AAQ+PYDVQ++DIDYM+ + DFT S F GFP
Sbjct: 375 YWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFP 434
Query: 63 ALINRMKADGMRVILILDPAISGNET--QPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRA 120
+N + +G ++++I+DPAIS N + +PY + RG + +++ + + G+++
Sbjct: 435 EFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPG 494
Query: 121 YVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRD 180
FPD+ + A WW +E E +N ++FDG+WIDMNE S+FV+G+VS GC
Sbjct: 495 QTVFPDYTNPNCAVWWTKEFELFHNQ-------VEFDGIWIDMNEVSNFVDGSVS-GCST 546
Query: 181 ASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQ 240
+LN+PP+ P + D L KTLCM++ Q + Y++HNLYG+S T EA +
Sbjct: 547 NNLNNPPFTPRI--LDGYLFCKTLCMDAVQ-----HWGKQYDIHNLYGYSMAVATAEAAK 599
Query: 241 EV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLF---QTGADIC 296
V +R ++TRSTF SG++A HWLGDNTA WD L+ SI G F LF G DIC
Sbjct: 600 TVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDIC 659
Query: 297 GFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DAAFVNISRNVLQTRYTL 354
GF D E+C RWMQLGAFYPFSRNHN G + QDP S+ D+ +N SR+ L RYTL
Sbjct: 660 GFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTL 719
Query: 355 LPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 414
LPYLYTL +AH+ G TV RPLLHEF D TWD+ QFL GP L++PVL+ A V A
Sbjct: 720 LPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMA 779
Query: 415 YFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRKNPLG 474
Y P A WYDY TG + R + + P D I LH+RGGYI P Q+P T SRKNPLG
Sbjct: 780 YVPDAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLG 839
Query: 475 LIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLAF 534
LIIALDENKEAKGELFWD+G+TKDTVA KVYLLCEFSVTQN LEV ISQSTYKDPNNLAF
Sbjct: 840 LIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAF 899
Query: 535 NEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIR 594
NEIKILG EEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDI+L LGEAYTVEWSIKIR
Sbjct: 900 NEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIR 959
Query: 595 DEEKIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADI 654
DEEKIDCYPDENG SAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADI
Sbjct: 960 DEEKIDCYPDENGASAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADI 1019
Query: 655 SLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPE 714
SLKSSV+ANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPN NRYEVPVPLNIPS+PSSTPE
Sbjct: 1020 SLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPE 1079
Query: 715 GQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEH 774
GQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTF+DMFIRISTRLPSKYLYGFGETEH
Sbjct: 1080 GQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETEH 1139
Query: 775 TSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQP 834
SYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQP
Sbjct: 1140 RSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQP 1199
Query: 835 LPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEI 894
LPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEI
Sbjct: 1200 LPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEI 1259
Query: 895 SSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPA 954
+SLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPA
Sbjct: 1260 ASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPA 1319
Query: 955 ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAY 1014
ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAY
Sbjct: 1320 ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAY 1379
Query: 1015 VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA 1074
VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA
Sbjct: 1380 VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA 1439
Query: 1075 SLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAVQE 1134
SLNHPPYMP+LESRDRGLSSKTLCMESQQILPDGS VQHYNVHNLYGWSQTRPTYEAVQE
Sbjct: 1440 SLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQE 1499
Query: 1135 VTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGF 1194
VTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGF
Sbjct: 1500 VTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGF 1559
Query: 1195 FQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYL 1254
FQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYL
Sbjct: 1560 FQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYL 1619
Query: 1255 YTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPR 1314
YTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPR
Sbjct: 1620 YTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPR 1679
Query: 1315 ARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIA 1374
ARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIA
Sbjct: 1680 ARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIA 1739
Query: 1375 LDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYI 1434
LDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYI
Sbjct: 1740 LDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYI 1799
Query: 1435 EIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL 1492
EIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL
Sbjct: 1800 EIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL 1857
Score = 1007 bits (2604), Expect = 0.0
Identities = 502/618 (81%), Positives = 526/618 (85%), Gaps = 31/618 (5%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG 60
MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG
Sbjct: 1238 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAG 1297
Query: 61 FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGK---- 116
FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGK
Sbjct: 1298 FPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPD 1357
Query: 117 -----------------LYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGM 159
LYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGM
Sbjct: 1358 FPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGM 1417
Query: 160 WIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQ 219
WIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQ
Sbjct: 1418 WIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQ 1477
Query: 220 HYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKS 279
HYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKS
Sbjct: 1478 HYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKS 1537
Query: 280 IIGSFYFLLF---QTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW 336
IIG F LF TGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW
Sbjct: 1538 IIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW 1597
Query: 337 DAAFVNISRNVLQTRYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLG 396
D AFVNISR VLQTRYTLLPYLYTLM KAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLG
Sbjct: 1598 DVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLG 1657
Query: 397 PAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYIL 456
PAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYIL
Sbjct: 1658 PAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYIL 1717
Query: 457 PWQEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNH 516
PWQEPALNTHLSR+ +G IALD+ A G LFWDDGQ+ DT K +Y L FS +QN
Sbjct: 1718 PWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNT 1777
Query: 517 LEVTISQSTY---KDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAI 573
++ I + Y +P L + EI +G ++V++ +G+ +P+ D +V
Sbjct: 1778 MQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGM--VITPSFNNDPTTQVLS 1835
Query: 574 I--TDINLFLGEAYTVEW 589
I TD N+ L ++ W
Sbjct: 1836 IDVTDRNISLHNFTSLTW 1853
Score = 684 bits (1766), Expect = 0.0
Identities = 385/912 (42%), Positives = 529/912 (58%), Gaps = 66/912 (7%)
Query: 593 IRDEEKIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFV-NDLYSVSDVQYNSH-GA 650
+ + E+I+C PD+ A C RGC W + VP+CY+ N Y V N++ G
Sbjct: 93 VNELERINCIPDQPPTKA-TCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGF 151
Query: 651 TADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPS 710
TA LK+ + F S N L L Y + FK+ D NNR+EVP ++ S
Sbjct: 152 TA--RLKNLPSSPVFGSNVDNVL-LTAEYQTSNRFHFKLTDQTNNRFEVPHE-HVQSFSG 207
Query: 711 STPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFG 770
+ Y V I + PF I++ R+S +++DS + F D F+++STRLPS +YG G
Sbjct: 208 NAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLG 267
Query: 771 ETEHTSYRRDLEWHTWGMFSRDQPP-GYKKNSYGVHPYYMGLEE-DGSAHGVLLLNSNAM 828
E H YR D+ W TW +F+RD P G N YG +++ LE+ G + GV L+NSNAM
Sbjct: 268 EHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAM 327
Query: 829 DVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGY 888
+V QP PA+TYRT GG+LDFYVFLG TPE V Q+Y ELIGRP + YW+LGF L RY Y
Sbjct: 328 EVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEY 387
Query: 889 QNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTL-SPKFAGFPALINRMKADGMRV 947
+ + + AAQ+PYDVQ++DIDYM+ + DFT S F GFP +N + +G ++
Sbjct: 388 GTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKL 447
Query: 948 ILILDPAISGN--ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWD 1005
++I+DPAIS N ++PY + RG + +++ + + G+VWP
Sbjct: 448 VIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWP-------------- 493
Query: 1006 SQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNG 1065
FPD+ + A WW +E E +N ++FDG+WIDMNE S+FV+G
Sbjct: 494 -------GQTVFPDYTNPNCAVWWTKEFELFHN-------QVEFDGIWIDMNEVSNFVDG 539
Query: 1066 AVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQH----YNVHNLYG 1121
+VS GC +LN+PP+ P + D L KTLCM++ VQH Y++HNLYG
Sbjct: 540 SVS-GCSTNNLNNPPFTPRI--LDGYLFCKTLCMDA---------VQHWGKQYDIHNLYG 587
Query: 1122 WSQTRPTYEAVQEV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFS 1180
+S T EA + V +R ++TRSTF SG++A HWLGDNTA WD L+ SI G++EF+
Sbjct: 588 YSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFN 647
Query: 1181 LFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DVAFVN 1238
LFGI G DICGF D E+C RWMQLGAFYPFSRNHN G + QDP S+ D +N
Sbjct: 648 LFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLN 707
Query: 1239 ISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVS 1298
SR L RYTLLPYLYTL +AH+ G TV RPLLHEF D TWD+ QFL GP L++
Sbjct: 708 SSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLIT 767
Query: 1299 PVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPA 1358
PVL+ A V AY P A WYDY TG + R + + P D I LH+RGGYI P Q+P
Sbjct: 768 PVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPN 827
Query: 1359 LNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHII 1418
T SR+ +G IALD+ A G LFWD+G++ DT +Y L FS +QN ++ +I
Sbjct: 828 TTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNIS 887
Query: 1419 FNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGM--VITPSFNNDPTTQVLSIDVTDR 1476
+ Y +P L + EI +G+ ++V++ +G+ +P+ D +V I TD
Sbjct: 888 QSTY---KDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAII--TDI 942
Query: 1477 NISLHNFTSLTW 1488
++ L ++ W
Sbjct: 943 DLLLGEAYTVEW 954
>gi|157364974 sucrase-isomaltase [Homo sapiens]
Length = 1827
Score = 1645 bits (4260), Expect = 0.0
Identities = 802/1503 (53%), Positives = 1032/1503 (68%), Gaps = 38/1503 (2%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFA 59
M YW+LGFQL R+ Y++ + + A IP+D Q +DIDYME + DFT F
Sbjct: 347 MPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFN 406
Query: 60 GFPALINRMKADGMRVILILDPAIS----GNETQPYPAFTRGVEDDVFIKYPNDGDIVWG 115
G P + + G + ++ILDPAIS N T Y + RG V+I + + G
Sbjct: 407 GLPQFVQDLHDHGQKYVIILDPAISIGRRANGTT-YATYERGNTQHVWINESDGSTPIIG 465
Query: 116 KLYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVS 175
+++ +PDF + WW E + Q +DG+WIDMNE SSF+ G+
Sbjct: 466 EVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQ-------YDGLWIDMNEVSSFIQGSTK 518
Query: 176 PGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPT 235
GC LN+PP+ P + D+ + SKT+CM++ Q + + Y+VH+LYG+S T
Sbjct: 519 -GCNVNKLNYPPFTPDI--LDKLMYSKTICMDAVQ-----NWGKQYDVHSLYGYSMAIAT 570
Query: 236 YEAVQEV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQ---T 291
+AVQ+V +R ++TRSTF SGR A HWLGDNTA+W+Q++ SI G F LF
Sbjct: 571 EQAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLV 630
Query: 292 GADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DAAFVNISRNVLQ 349
GADICGF + E+C RWMQLGAFYPFSRNHN+ G QDP + ++ V SR L
Sbjct: 631 GADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLT 690
Query: 350 TRYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNA 409
RYTLLP+LYTL KAH G TV RP+LHEF D +W D++FL GPA L++PVL++ A
Sbjct: 691 IRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGA 750
Query: 410 RNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSR 469
V+AY P A WYDY +G R + + P D I LH+RGGYI+P QEP + T SR
Sbjct: 751 DTVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASR 810
Query: 470 KNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDP 529
KNPLGLI+AL EN AKG+ FWDDG+TKDT+ Y+L FSV+ N L++ + S+Y++
Sbjct: 811 KNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEG 870
Query: 530 NNLAFNEIKILGMEEP-SNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVE 588
LAF +KILG+ + + V V N P TYD++ +V +I D+ L LG ++V+
Sbjct: 871 TTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQ 930
Query: 589 WSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNS-SGVPFCYFV--NDLYSVSDVQY 645
W+ + E+ +CYPD + + + CT RGC+W +S S P CYF ++ YSV+ +Y
Sbjct: 931 WNQIFSENERFNCYPDADLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARY 990
Query: 646 NSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNI 705
+S G TAD+ L ++ PS P++ LR++V YHKN+MLQFKIYDP RYEVPVPLNI
Sbjct: 991 SSMGITADLQLNTANARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNI 1050
Query: 706 PSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKY 765
P+ P ST E +LYDV IK+NPFGI+IRR+S+G +IWDS L GF FND FI+ISTRLPS+Y
Sbjct: 1051 PTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEY 1110
Query: 766 LYGFGETEHTSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNS 825
+YGFGE EHT+++RDL W+TWGMF+RDQPPGYK NSYG HPYYM LEE+G+AHGV LLNS
Sbjct: 1111 IYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNS 1170
Query: 826 NAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCR 885
NAMDVTFQP PALTYRT GG+LDFY+FLGPTPE+ T+QY E+IG PVM YW+LGFQLCR
Sbjct: 1171 NAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCR 1230
Query: 886 YGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGM 945
YGY N SE+ LYD MVAA IPYDVQY+DIDYMERQLDFT+ F P +++++ +GM
Sbjct: 1231 YGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGM 1290
Query: 946 RVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWD 1005
R I+ILDPAISGNET+ YPAF RG ++DVF+K+PN DI W KVWPD P++ ++ +L D
Sbjct: 1291 RYIIILDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTED 1350
Query: 1006 SQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNG 1065
V RA+VAFPDFFR STA+WW REI + YN +KFDG+WIDMNEPSSFVNG
Sbjct: 1351 EAVNASRAHVAFPDFFRTSTAEWWAREIVDFYN------EKMKFDGLWIDMNEPSSFVNG 1404
Query: 1066 AVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQT 1125
+ CR+ LN+PPY P L R GL +T+CME++QIL DG+ V HY+VHNLYGWSQ
Sbjct: 1405 TTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQM 1464
Query: 1126 RPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGIS 1185
+PT++A+Q+ TG+RG+VI+RST+P+SGRW GHWLGDN A WD + KSIIGMMEFSLFG+S
Sbjct: 1465 KPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMS 1524
Query: 1186 YTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQ 1245
YTGADICGFF ++EY +C RWMQLGAFYP+SRNHN TRRQDP SW+ F +SR +L
Sbjct: 1525 YTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILN 1584
Query: 1246 TRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNA 1305
RYTLLPY YT MH+ H G TV+RPLLHEF ++ TWDI QFL GPAF+V+PVLE
Sbjct: 1585 IRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYV 1644
Query: 1306 RNVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSR 1365
+ V AY P ARW+DY+TG DI RG+++T A D INLHVRGG+ILP QEPA NT SR
Sbjct: 1645 QTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSR 1704
Query: 1366 QKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITG 1425
QK M +A DD A G LFWDDG+SIDTY + LY F+ +Q T+ S I+ YI
Sbjct: 1705 QKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKRGYI-N 1763
Query: 1426 TNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTS 1485
+ +LG + +WG G+ PV +V+++ +G + FN D T +L ID+T N++L
Sbjct: 1764 KSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIE 1823
Query: 1486 LTW 1488
+ W
Sbjct: 1824 INW 1826
Score = 657 bits (1696), Expect = 0.0
Identities = 372/903 (41%), Positives = 514/903 (56%), Gaps = 57/903 (6%)
Query: 598 KIDCYPDENGDSAENCTARGCIWEASNSSGVPFCYFV-NDLYSVSDVQYNSHGATADISL 656
+I+C P E + C RGC W N S +P+C+FV N Y+V D+ S G A ++
Sbjct: 74 RINCIP-EQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAKLN- 131
Query: 657 KSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNNNRYEVPVPLNIPSVPSSTPEGQ 716
+ + +N + +FKI DPNN RYEVP + T
Sbjct: 132 --RIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQY-VKEFTGPTVSDT 188
Query: 717 LYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTS 776
LYDV + +NPF I++ RKS G ++D+ + ++D +++ISTRLPS Y+YG GE H
Sbjct: 189 LYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKR 248
Query: 777 YRRDLEWHTWGMFSRDQPPGYKKNS-YGVHPYYMGLEE-DGSAHGVLLLNSNAMDVTFQP 834
+R DL W TW +F+RDQ PG N+ YG ++M +E+ G + GV L+NSNAM++ QP
Sbjct: 249 FRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQP 308
Query: 835 LPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEI 894
P +TYR TGG+LDFY+ LG TPE V QQY +L+G P M YW+LGFQL R+ Y++ +
Sbjct: 309 TPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVV 368
Query: 895 SSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILDP 953
+ A IP+D Q +DIDYME + DFT F G P + + G + ++ILDP
Sbjct: 369 KEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDP 428
Query: 954 AIS----GNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVE 1009
AIS N T Y + RG V+I + + G+VWP
Sbjct: 429 AISIGRRANGT-TYATYERGNTQHVWINESDGSTPIIGEVWP------------------ 469
Query: 1010 LYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSP 1069
+PDF + WW E + + +++DG+WIDMNE SSF+ G+ +
Sbjct: 470 ---GLTVYPDFTNPNCIDWWANECSIFH-------QEVQYDGLWIDMNEVSSFIQGS-TK 518
Query: 1070 GCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTY 1129
GC LN+PP+ P + D+ + SKT+CM++ Q + + Y+VH+LYG+S T
Sbjct: 519 GCNVNKLNYPPFTP--DILDKLMYSKTICMDAVQ-----NWGKQYDVHSLYGYSMAIATE 571
Query: 1130 EAVQEV-TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTG 1188
+AVQ+V +R ++TRSTF SGR A HWLGDNTA+W+Q++ SI GM+EFSLFGI G
Sbjct: 572 QAVQKVFPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVG 631
Query: 1189 ADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSW--DVAFVNISRTVLQT 1246
ADICGF + E+C RWMQLGAFYPFSRNHN+ G QDP + + V SR L
Sbjct: 632 ADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTI 691
Query: 1247 RYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNAR 1306
RYTLLP+LYTL +KAH G TV RP+LHEF D +W D++FL GPA L++PVL++ A
Sbjct: 692 RYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGAD 751
Query: 1307 NVTAYFPRARWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQ 1366
V+AY P A WYDY +G R + + P D I LH+RGGYI+P QEP + T SR+
Sbjct: 752 TVSAYIPDAIWYDYESGAKRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRK 811
Query: 1367 KFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGT 1426
+G +AL + TA G FWDDG++ DT G Y L +FS S NT+ ++Y GT
Sbjct: 812 NPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGT 871
Query: 1427 NPLKLGYIEIWGV-GSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTS 1485
L ++I G+ SV V+ + M +F D + QVL I D ++L S
Sbjct: 872 T-LAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLI--ADLKLNLGRNFS 928
Query: 1486 LTW 1488
+ W
Sbjct: 929 VQW 931
>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 625 bits (1612), Expect = e-179
Identities = 358/921 (38%), Positives = 497/921 (53%), Gaps = 81/921 (8%)
Query: 582 GEAYTVEWSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNSS------GVPFCYFVN 635
G V + + DC PD+ + E C ARGC + + G P+C+F
Sbjct: 73 GRPRAVPTQCDVPPNSRFDCAPDK-AITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPP 131
Query: 636 DL--YSVSDVQYNSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPN 693
Y + ++ + G TA ++ + FP + LRLDV L F I DP
Sbjct: 132 SYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHFTIKDPA 187
Query: 694 NNRYEVPVPLNIPSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDM 753
N RYEVP L P V S P LY V + PFG+ +RR+ G ++ ++ + F D
Sbjct: 188 NRRYEVP--LETPHVHSRAPS-PLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQ 244
Query: 754 FIRISTRLPSKYLYGFGETEHTS-YRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLE 812
F+++ST LPS+Y+ G E H S W +++RD P N YG HP+Y+ LE
Sbjct: 245 FLQLSTSLPSQYITGLAE--HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALE 302
Query: 813 EDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPV 872
+ GSAHGV LLNSNAMDV QP PAL++R+TGG+LD Y+FLGP P+ V QQY +++G P
Sbjct: 303 DGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPF 362
Query: 873 MVPYWSLGFQLCRYGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 931
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 932 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVW 990
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GKVW
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 991 PDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFD 1050
P GS AFPDF + WW+ + E ++ + FD
Sbjct: 482 P--------GS-------------TAFPDFTNPTALAWWEDMVAEFHDQ-------VPFD 513
Query: 1051 GMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSP 1110
GMWIDMNEPS+F+ G+ GC + L +PPY+P + L + T+C S Q L
Sbjct: 514 GMWIDMNEPSNFIRGS-EDGCPNNELENPPYVPGVVGGT--LQAATICASSHQFLST--- 567
Query: 1111 VQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLK 1170
HYN+HNLYG ++ ++ A+ + G R VI+RSTF GR+AGHW GD ++W+QL
Sbjct: 568 --HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLA 625
Query: 1171 KSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPV 1230
S+ +++F+L G+ GAD+CGF + E+CVRW QLGAFYPF RNHN++ + Q+P
Sbjct: 626 SSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPY 685
Query: 1231 SWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFL 1290
S+ R L RY LLP+LYTL H+AH G TV RPL EF D TW +D Q L
Sbjct: 686 SFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLL 745
Query: 1291 LGPAFLVSPVLERNARNVTAYFPRARWYDYYT-----------------GVDINARGEWK 1333
G A L++PVL+ VT YFP WYD T I++ G+W
Sbjct: 746 WGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWV 805
Query: 1334 TLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSI 1393
TLPAPLD IN+H+R GYI+P Q P L T SRQ+ M +AL G A G LFWDDG+S+
Sbjct: 806 TLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESL 865
Query: 1394 DTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSG 1453
+ +G Y F A NT+ + ++ + L+L + + GV + P +S V
Sbjct: 866 EVLERGAYTQVIFLARNNTIVNELV--RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVP- 922
Query: 1454 MVITPSFNNDPTTQVLSIDVT 1474
+F P T+VL I V+
Sbjct: 923 ---VSNFTYSPDTKVLDICVS 940
Score = 431 bits (1107), Expect = e-120
Identities = 238/611 (38%), Positives = 333/611 (54%), Gaps = 44/611 (7%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 59
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 60 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLY 118
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GK++
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 119 RAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGC 178
AFPDF + WW+ + E ++ + FDGMWIDMNEPS+F+ G+ GC
Sbjct: 482 PGSTAFPDFTNPTALAWWEDMVAEFHDQ-------VPFDGMWIDMNEPSNFIRGS-EDGC 533
Query: 179 RDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEA 238
+ L +PPY+P + L + T+C S Q L HYN+HNLYG ++ ++ A
Sbjct: 534 PNNELENPPYVPGVVGGT--LQAATICASSHQFLST-----HYNLHNLYGLTEAIASHRA 586
Query: 239 VQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQT---GADI 295
+ + G R VI+RSTF GR+AGHW GD ++W+QL S+ F L GAD+
Sbjct: 587 LVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADV 646
Query: 296 CGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLL 355
CGF + E+CVRW QLGAFYPF RNHN++ + Q+P S+ R L RY LL
Sbjct: 647 CGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALL 706
Query: 356 PYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAY 415
P+LYTL +AH G TV RPL EF D TW +D Q L G A L++PVL+ VT Y
Sbjct: 707 PHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGY 766
Query: 416 FPRARWYDYYT-----------------GVDINARGEWKTLPAPLDHINLHVRGGYILPW 458
FP WYD T I++ G+W TLPAPLD IN+H+R GYI+P
Sbjct: 767 FPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPL 826
Query: 459 QEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLE 518
Q P L T SR+ P+ L +AL + EA+GELFWDDG++ + + + Y F N +
Sbjct: 827 QGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIV 886
Query: 519 VTISQSTYKDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIN 578
+ + T + L ++ +LG+ V NGVP TY + KV I ++
Sbjct: 887 NELVRVT-SEGAGLQLQKVTVLGVATAPQ-QVLSNGVPVS---NFTYSPDTKVLDIC-VS 940
Query: 579 LFLGEAYTVEW 589
L +GE + V W
Sbjct: 941 LLMGEQFLVSW 951
>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 625 bits (1612), Expect = e-179
Identities = 358/921 (38%), Positives = 497/921 (53%), Gaps = 81/921 (8%)
Query: 582 GEAYTVEWSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNSS------GVPFCYFVN 635
G V + + DC PD+ + E C ARGC + + G P+C+F
Sbjct: 73 GRPRAVPTQCDVPPNSRFDCAPDK-AITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPP 131
Query: 636 DL--YSVSDVQYNSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPN 693
Y + ++ + G TA ++ + FP + LRLDV L F I DP
Sbjct: 132 SYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHFTIKDPA 187
Query: 694 NNRYEVPVPLNIPSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDM 753
N RYEVP L P V S P LY V + PFG+ +RR+ G ++ ++ + F D
Sbjct: 188 NRRYEVP--LETPHVHSRAPS-PLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQ 244
Query: 754 FIRISTRLPSKYLYGFGETEHTS-YRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLE 812
F+++ST LPS+Y+ G E H S W +++RD P N YG HP+Y+ LE
Sbjct: 245 FLQLSTSLPSQYITGLAE--HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALE 302
Query: 813 EDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPV 872
+ GSAHGV LLNSNAMDV QP PAL++R+TGG+LD Y+FLGP P+ V QQY +++G P
Sbjct: 303 DGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPF 362
Query: 873 MVPYWSLGFQLCRYGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 931
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 932 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVW 990
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GKVW
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 991 PDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFD 1050
P GS AFPDF + WW+ + E ++ + FD
Sbjct: 482 P--------GS-------------TAFPDFTNPTALAWWEDMVAEFHDQ-------VPFD 513
Query: 1051 GMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSP 1110
GMWIDMNEPS+F+ G+ GC + L +PPY+P + L + T+C S Q L
Sbjct: 514 GMWIDMNEPSNFIRGS-EDGCPNNELENPPYVPGVVGGT--LQAATICASSHQFLST--- 567
Query: 1111 VQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLK 1170
HYN+HNLYG ++ ++ A+ + G R VI+RSTF GR+AGHW GD ++W+QL
Sbjct: 568 --HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLA 625
Query: 1171 KSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPV 1230
S+ +++F+L G+ GAD+CGF + E+CVRW QLGAFYPF RNHN++ + Q+P
Sbjct: 626 SSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPY 685
Query: 1231 SWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFL 1290
S+ R L RY LLP+LYTL H+AH G TV RPL EF D TW +D Q L
Sbjct: 686 SFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLL 745
Query: 1291 LGPAFLVSPVLERNARNVTAYFPRARWYDYYT-----------------GVDINARGEWK 1333
G A L++PVL+ VT YFP WYD T I++ G+W
Sbjct: 746 WGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWV 805
Query: 1334 TLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSI 1393
TLPAPLD IN+H+R GYI+P Q P L T SRQ+ M +AL G A G LFWDDG+S+
Sbjct: 806 TLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESL 865
Query: 1394 DTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSG 1453
+ +G Y F A NT+ + ++ + L+L + + GV + P +S V
Sbjct: 866 EVLERGAYTQVIFLARNNTIVNELV--RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVP- 922
Query: 1454 MVITPSFNNDPTTQVLSIDVT 1474
+F P T+VL I V+
Sbjct: 923 ---VSNFTYSPDTKVLDICVS 940
Score = 431 bits (1107), Expect = e-120
Identities = 238/611 (38%), Positives = 333/611 (54%), Gaps = 44/611 (7%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 59
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 60 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLY 118
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GK++
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 119 RAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGC 178
AFPDF + WW+ + E ++ + FDGMWIDMNEPS+F+ G+ GC
Sbjct: 482 PGSTAFPDFTNPTALAWWEDMVAEFHDQ-------VPFDGMWIDMNEPSNFIRGS-EDGC 533
Query: 179 RDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEA 238
+ L +PPY+P + L + T+C S Q L HYN+HNLYG ++ ++ A
Sbjct: 534 PNNELENPPYVPGVVGGT--LQAATICASSHQFLST-----HYNLHNLYGLTEAIASHRA 586
Query: 239 VQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQT---GADI 295
+ + G R VI+RSTF GR+AGHW GD ++W+QL S+ F L GAD+
Sbjct: 587 LVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADV 646
Query: 296 CGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLL 355
CGF + E+CVRW QLGAFYPF RNHN++ + Q+P S+ R L RY LL
Sbjct: 647 CGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALL 706
Query: 356 PYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAY 415
P+LYTL +AH G TV RPL EF D TW +D Q L G A L++PVL+ VT Y
Sbjct: 707 PHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGY 766
Query: 416 FPRARWYDYYT-----------------GVDINARGEWKTLPAPLDHINLHVRGGYILPW 458
FP WYD T I++ G+W TLPAPLD IN+H+R GYI+P
Sbjct: 767 FPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPL 826
Query: 459 QEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLE 518
Q P L T SR+ P+ L +AL + EA+GELFWDDG++ + + + Y F N +
Sbjct: 827 QGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIV 886
Query: 519 VTISQSTYKDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIN 578
+ + T + L ++ +LG+ V NGVP TY + KV I ++
Sbjct: 887 NELVRVT-SEGAGLQLQKVTVLGVATAPQ-QVLSNGVPVS---NFTYSPDTKVLDIC-VS 940
Query: 579 LFLGEAYTVEW 589
L +GE + V W
Sbjct: 941 LLMGEQFLVSW 951
>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 625 bits (1612), Expect = e-179
Identities = 358/921 (38%), Positives = 497/921 (53%), Gaps = 81/921 (8%)
Query: 582 GEAYTVEWSIKIRDEEKIDCYPDENGDSAENCTARGCIWEASNSS------GVPFCYFVN 635
G V + + DC PD+ + E C ARGC + + G P+C+F
Sbjct: 73 GRPRAVPTQCDVPPNSRFDCAPDK-AITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPP 131
Query: 636 DL--YSVSDVQYNSHGATADISLKSSVHANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPN 693
Y + ++ + G TA ++ + FP + LRLDV L F I DP
Sbjct: 132 SYPSYKLENLSSSEMGYTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHFTIKDPA 187
Query: 694 NNRYEVPVPLNIPSVPSSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFNDM 753
N RYEVP L P V S P LY V + PFG+ +RR+ G ++ ++ + F D
Sbjct: 188 NRRYEVP--LETPHVHSRAPS-PLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQ 244
Query: 754 FIRISTRLPSKYLYGFGETEHTS-YRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLE 812
F+++ST LPS+Y+ G E H S W +++RD P N YG HP+Y+ LE
Sbjct: 245 FLQLSTSLPSQYITGLAE--HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALE 302
Query: 813 EDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPV 872
+ GSAHGV LLNSNAMDV QP PAL++R+TGG+LD Y+FLGP P+ V QQY +++G P
Sbjct: 303 DGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPF 362
Query: 873 MVPYWSLGFQLCRYGYQNDSEISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 931
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 932 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVW 990
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GKVW
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 991 PDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFD 1050
P GS AFPDF + WW+ + E ++ + FD
Sbjct: 482 P--------GS-------------TAFPDFTNPTALAWWEDMVAEFHDQ-------VPFD 513
Query: 1051 GMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSP 1110
GMWIDMNEPS+F+ G+ GC + L +PPY+P + L + T+C S Q L
Sbjct: 514 GMWIDMNEPSNFIRGS-EDGCPNNELENPPYVPGVVGGT--LQAATICASSHQFLST--- 567
Query: 1111 VQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLK 1170
HYN+HNLYG ++ ++ A+ + G R VI+RSTF GR+AGHW GD ++W+QL
Sbjct: 568 --HYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLA 625
Query: 1171 KSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPV 1230
S+ +++F+L G+ GAD+CGF + E+CVRW QLGAFYPF RNHN++ + Q+P
Sbjct: 626 SSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPY 685
Query: 1231 SWDVAFVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFL 1290
S+ R L RY LLP+LYTL H+AH G TV RPL EF D TW +D Q L
Sbjct: 686 SFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLL 745
Query: 1291 LGPAFLVSPVLERNARNVTAYFPRARWYDYYT-----------------GVDINARGEWK 1333
G A L++PVL+ VT YFP WYD T I++ G+W
Sbjct: 746 WGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWV 805
Query: 1334 TLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSI 1393
TLPAPLD IN+H+R GYI+P Q P L T SRQ+ M +AL G A G LFWDDG+S+
Sbjct: 806 TLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESL 865
Query: 1394 DTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSG 1453
+ +G Y F A NT+ + ++ + L+L + + GV + P +S V
Sbjct: 866 EVLERGAYTQVIFLARNNTIVNELV--RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVP- 922
Query: 1454 MVITPSFNNDPTTQVLSIDVT 1474
+F P T+VL I V+
Sbjct: 923 ---VSNFTYSPDTKVLDICVS 940
Score = 431 bits (1107), Expect = e-120
Identities = 238/611 (38%), Positives = 333/611 (54%), Gaps = 44/611 (7%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FA 59
M PYW LGF LCR+GY + + + + M A P DVQ++D+DYM+ + DFT + F
Sbjct: 363 MPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFR 422
Query: 60 GFPALINRMKADGMRVILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLY 118
FPA++ + G R ++I+DPAIS + Y + G+ VFI ++ GK++
Sbjct: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI-GKVW 481
Query: 119 RAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGC 178
AFPDF + WW+ + E ++ + FDGMWIDMNEPS+F+ G+ GC
Sbjct: 482 PGSTAFPDFTNPTALAWWEDMVAEFHDQ-------VPFDGMWIDMNEPSNFIRGS-EDGC 533
Query: 179 RDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEA 238
+ L +PPY+P + L + T+C S Q L HYN+HNLYG ++ ++ A
Sbjct: 534 PNNELENPPYVPGVVGGT--LQAATICASSHQFLST-----HYNLHNLYGLTEAIASHRA 586
Query: 239 VQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQT---GADI 295
+ + G R VI+RSTF GR+AGHW GD ++W+QL S+ F L GAD+
Sbjct: 587 LVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADV 646
Query: 296 CGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLL 355
CGF + E+CVRW QLGAFYPF RNHN++ + Q+P S+ R L RY LL
Sbjct: 647 CGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALL 706
Query: 356 PYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAY 415
P+LYTL +AH G TV RPL EF D TW +D Q L G A L++PVL+ VT Y
Sbjct: 707 PHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGY 766
Query: 416 FPRARWYDYYT-----------------GVDINARGEWKTLPAPLDHINLHVRGGYILPW 458
FP WYD T I++ G+W TLPAPLD IN+H+R GYI+P
Sbjct: 767 FPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPL 826
Query: 459 QEPALNTHLSRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLE 518
Q P L T SR+ P+ L +AL + EA+GELFWDDG++ + + + Y F N +
Sbjct: 827 QGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIV 886
Query: 519 VTISQSTYKDPNNLAFNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIN 578
+ + T + L ++ +LG+ V NGVP TY + KV I ++
Sbjct: 887 NELVRVT-SEGAGLQLQKVTVLGVATAPQ-QVLSNGVPVS---NFTYSPDTKVLDIC-VS 940
Query: 579 LFLGEAYTVEW 589
L +GE + V W
Sbjct: 941 LLMGEQFLVSW 951
>gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens]
Length = 966
Score = 253 bits (645), Expect = 1e-66
Identities = 191/652 (29%), Positives = 302/652 (46%), Gaps = 70/652 (10%)
Query: 834 PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 893
P + + + G++D ++ LGP+ V +QY L G + P +SLG+ R+ Y+++++
Sbjct: 371 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 430
Query: 894 ISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILD 952
+ + +P DV + DI++ + + FT P +F ++ R+ + +++ I+D
Sbjct: 431 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 490
Query: 953 PAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYR 1012
P I + R + +++K DG G WP GS
Sbjct: 491 PHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWP--------GS----------- 528
Query: 1013 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1072
+PDF + WW Y+N + +L +W DMNEPS F V
Sbjct: 529 --AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVFNGPEV----- 576
Query: 1073 DASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAV 1132
T+ ++Q +H +VHN+YG T + +
Sbjct: 577 -----------------------TMLKDAQHY----GGWEHRDVHNIYGLYVHMATADGL 609
Query: 1133 QEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1190
++ +G +R V+ R+ F S R+ W GDNTA WD LK SI + L G+S+ GAD
Sbjct: 610 RQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGAD 669
Query: 1191 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1250
+ GFF++ E E+ VRW Q+GA+ PF R H + T R++P +I R L RY+L
Sbjct: 670 VGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSL 729
Query: 1251 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1310
LP+ YTL+++AH EG+ V+RPL ++ D T++ID Q+LLG A LV PV + A V
Sbjct: 730 LPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQV 789
Query: 1311 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRQK 1367
Y P WYD + + + LP L I + RGG I+P W ++ +
Sbjct: 790 YLPGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDD 848
Query: 1368 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTN 1427
+ +AL +GTA G LF DDG + + + + L FS S NT+ S T
Sbjct: 849 PITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFET- 907
Query: 1428 PLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1479
P+ + + I G G P V + SF +DP T VL + N++
Sbjct: 908 PIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVA 958
Score = 234 bits (598), Expect = 4e-61
Identities = 174/601 (28%), Positives = 285/601 (47%), Gaps = 55/601 (9%)
Query: 3 PYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGF 61
P +SLG+ R+ Y++++++ + +P DV + DI++ + + FT P +F
Sbjct: 412 PLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQP 471
Query: 62 PALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRAY 121
++ R+ + +++ I+DP I + R + +++K DG G +
Sbjct: 472 RTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWPGS 528
Query: 122 VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA 181
+PDF + WW Y+N + +L +W DMNEPS F NG +DA
Sbjct: 529 AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVF-NGPEVTMLKDA 582
Query: 182 SLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQE 241
H + H +VHN+YG T + +++
Sbjct: 583 Q--------HYGGWE-----------------------HRDVHNIYGLYVHMATADGLRQ 611
Query: 242 VTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSI---IGSFYFLLFQTGADIC 296
+G +R V+ R+ F S R+ W GDNTA WD LK SI + L GAD+
Sbjct: 612 RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 671
Query: 297 GFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLP 356
GFF++ E E+ VRW Q+GA+ PF R H + T R++P + +I R+ L RY+LLP
Sbjct: 672 GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 731
Query: 357 YLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYF 416
+ YTL+ +AH EG+ V+RPL ++ D T++ID Q+LLG A LV PV + A V Y
Sbjct: 732 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 791
Query: 417 PRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRKNPL 473
P WYD + + + LP L I + RGG I+P W ++ + +P+
Sbjct: 792 PGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPI 850
Query: 474 GLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLA 533
L +AL A+GELF DDG T + ++ +LL FS + N L + + +
Sbjct: 851 TLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIW 910
Query: 534 FNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKI 593
+ I+G +P+ V ++ G P ++ + +D V ++ + + +WSI +
Sbjct: 911 IERVVIIGAGKPAAVVLQTKGSP-ESRLSFQHDPETSVLVLRKPGINVAS----DWSIHL 965
Query: 594 R 594
R
Sbjct: 966 R 966
>gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens]
Length = 944
Score = 253 bits (645), Expect = 1e-66
Identities = 191/652 (29%), Positives = 302/652 (46%), Gaps = 70/652 (10%)
Query: 834 PLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSE 893
P + + + G++D ++ LGP+ V +QY L G + P +SLG+ R+ Y+++++
Sbjct: 349 PQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEAD 408
Query: 894 ISSLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILD 952
+ + +P DV + DI++ + + FT P +F ++ R+ + +++ I+D
Sbjct: 409 VLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVD 468
Query: 953 PAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYR 1012
P I + R + +++K DG G WP GS
Sbjct: 469 PHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWP--------GS----------- 506
Query: 1013 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1072
+PDF + WW Y+N + +L +W DMNEPS F V
Sbjct: 507 --AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVFNGPEV----- 554
Query: 1073 DASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAV 1132
T+ ++Q +H +VHN+YG T + +
Sbjct: 555 -----------------------TMLKDAQHY----GGWEHRDVHNIYGLYVHMATADGL 587
Query: 1133 QEVTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1190
++ +G +R V+ R+ F S R+ W GDNTA WD LK SI + L G+S+ GAD
Sbjct: 588 RQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGAD 647
Query: 1191 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1250
+ GFF++ E E+ VRW Q+GA+ PF R H + T R++P +I R L RY+L
Sbjct: 648 VGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSL 707
Query: 1251 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1310
LP+ YTL+++AH EG+ V+RPL ++ D T++ID Q+LLG A LV PV + A V
Sbjct: 708 LPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQV 767
Query: 1311 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRQK 1367
Y P WYD + + + LP L I + RGG I+P W ++ +
Sbjct: 768 YLPGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDD 826
Query: 1368 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTN 1427
+ +AL +GTA G LF DDG + + + + L FS S NT+ S T
Sbjct: 827 PITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFET- 885
Query: 1428 PLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1479
P+ + + I G G P V + SF +DP T VL + N++
Sbjct: 886 PIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVA 936
Score = 234 bits (598), Expect = 4e-61
Identities = 174/601 (28%), Positives = 285/601 (47%), Gaps = 55/601 (9%)
Query: 3 PYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGF 61
P +SLG+ R+ Y++++++ + +P DV + DI++ + + FT P +F
Sbjct: 390 PLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQP 449
Query: 62 PALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYRAY 121
++ R+ + +++ I+DP I + R + +++K DG G +
Sbjct: 450 RTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNL--GLYVK-TRDGSDYEGWCWPGS 506
Query: 122 VAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDA 181
+PDF + WW Y+N + +L +W DMNEPS F NG +DA
Sbjct: 507 AGYPDFTNPTMRAWWANMFS--YDNYEGSAPNLF---VWNDMNEPSVF-NGPEVTMLKDA 560
Query: 182 SLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQE 241
H + H +VHN+YG T + +++
Sbjct: 561 Q--------HYGGWE-----------------------HRDVHNIYGLYVHMATADGLRQ 589
Query: 242 VTG--QRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSI---IGSFYFLLFQTGADIC 296
+G +R V+ R+ F S R+ W GDNTA WD LK SI + L GAD+
Sbjct: 590 RSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVG 649
Query: 297 GFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRYTLLP 356
GFF++ E E+ VRW Q+GA+ PF R H + T R++P + +I R+ L RY+LLP
Sbjct: 650 GFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLP 709
Query: 357 YLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYF 416
+ YTL+ +AH EG+ V+RPL ++ D T++ID Q+LLG A LV PV + A V Y
Sbjct: 710 FWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYL 769
Query: 417 PRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILP-WQEPALNTHLSRKNPL 473
P WYD + + + LP L I + RGG I+P W ++ + +P+
Sbjct: 770 PGQGEVWYDIQS-YQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPI 828
Query: 474 GLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDPNNLA 533
L +AL A+GELF DDG T + ++ +LL FS + N L + + +
Sbjct: 829 TLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIW 888
Query: 534 FNEIKILGMEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKI 593
+ I+G +P+ V ++ G P ++ + +D V ++ + + +WSI +
Sbjct: 889 IERVVIIGAGKPAAVVLQTKGSP-ESRLSFQHDPETSVLVLRKPGINVAS----DWSIHL 943
Query: 594 R 594
R
Sbjct: 944 R 944
>gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
Length = 914
Score = 248 bits (632), Expect = 4e-65
Identities = 199/716 (27%), Positives = 320/716 (44%), Gaps = 104/716 (14%)
Query: 798 KKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTT-------------- 843
K YG PY + + G G+ LN++ V PA+ Y T
Sbjct: 261 KMGIYGSVPYLLA-HKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSR 319
Query: 844 --------GGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIS 895
G++D ++ GPTP V +QY+ L G M P +SLG+ CR+ Y+++ ++
Sbjct: 320 THVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVK 379
Query: 896 SLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILDPA 954
++ IPYD + DI++ E + FT +F + +++ ++++I DP
Sbjct: 380 AVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPH 439
Query: 955 ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQV--ELYR 1012
I + Y + + + F+K +G+ G WP ++ LD+ + E Y
Sbjct: 440 IKIDPD--YSVYVKAKDQGFFVKN-QEGEDFEGVCWPG-----LSSYLDFTNPKVREWYS 491
Query: 1013 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1072
+ AFP ++ ST + F +W DMNEPS F G +
Sbjct: 492 SLFAFP-VYQGST--------------------DILF--LWNDMNEPSVF-RGPEQTMQK 527
Query: 1073 DASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAV 1132
+A ++H + +H +HN+YG+ T E +
Sbjct: 528 NA-IHHGNW------------------------------EHRELHNIYGFYHQMATAEGL 556
Query: 1133 --QEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1190
+ +R V+TRS F S ++ W GDNTA W LK SI ++ S+ GIS+ GAD
Sbjct: 557 IKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGAD 616
Query: 1191 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1250
I GF + E E+ VRW Q GA+ PF R H T+ T+R++P + + R ++ RY L
Sbjct: 617 IGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGL 676
Query: 1251 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1310
LPY Y+L + AH V+RPL EF + T+D++ +++LG A LV PV E A V
Sbjct: 677 LPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDV 736
Query: 1311 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEP-ALNTHLSRQK 1367
+ P + WYDY T G +P LD I + RGG ++P + +T +
Sbjct: 737 FLPGSNEVWYDYKTFAHWEG-GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTES 795
Query: 1368 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYI--TG 1425
G ++AL +G++ G L+ DDG S + + FS S ++ N++ G
Sbjct: 796 SYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFS-----FCSSVLINSFADQRG 850
Query: 1426 TNPLK--LGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1479
P K + I + G P + + S G +F T +LS++ NI+
Sbjct: 851 HYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIA 906
Score = 216 bits (550), Expect = 1e-55
Identities = 168/605 (27%), Positives = 277/605 (45%), Gaps = 60/605 (9%)
Query: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFA 59
M P +SLG+ CR+ Y+++ ++ ++ IPYD + DI++ E + FT +F
Sbjct: 357 MPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFP 416
Query: 60 GFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYR 119
+ +++ ++++I DP I + Y + + + F+K +G+ G +
Sbjct: 417 NPKRMQELLRSKKRKLVVISDPHIKIDPD--YSVYVKAKDQGFFVKN-QEGEDFEGVCWP 473
Query: 120 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 179
++ DF +W+ L+ P + S +W DMNEPS F G +
Sbjct: 474 GLSSYLDFTNPKVREWYS----SLFAFPVY-QGSTDILFLWNDMNEPSVF-RGPEQTMQK 527
Query: 180 DASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAV 239
+A ++H + +H +HN+YG+ T E +
Sbjct: 528 NA-IHHGNW------------------------------EHRELHNIYGFYHQMATAEGL 556
Query: 240 --QEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGSFYFLLFQTG----- 292
+ +R V+TRS F S ++ W GDNTA W LK SI L TG
Sbjct: 557 IKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISI--PMLLTLSITGISFCG 614
Query: 293 ADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQTRY 352
ADI GF + E E+ VRW Q GA+ PF R H T+ T+R++P + + R ++ RY
Sbjct: 615 ADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERY 674
Query: 353 TLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNV 412
LLPY Y+L AH V+RPL EF + T+D++ +++LG A LV PV E A V
Sbjct: 675 GLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTV 734
Query: 413 TAYFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEP-ALNTHLSR 469
+ P + WYDY T G +P LD I + RGG ++P + +T
Sbjct: 735 DVFLPGSNEVWYDYKTFAHWEG-GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMT 793
Query: 470 KNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYKDP 529
++ GL +AL + GEL+ DDG + + +K +L +FS + L + + P
Sbjct: 794 ESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYP 853
Query: 530 NNLAFNEIKILGM-EEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVE 588
+ +I +LG +EPS+VT H+ TY + + + ++L + +
Sbjct: 854 SKCVVEKILVLGFRKEPSSVTT-HSSDGKDQPVAFTYCAKTSILSLEKLSLNI----ATD 908
Query: 589 WSIKI 593
W ++I
Sbjct: 909 WEVRI 913
>gi|153791946 hypothetical protein LOC57462 [Homo sapiens]
Length = 714
Score = 69.3 bits (168), Expect = 3e-11
Identities = 96/394 (24%), Positives = 151/394 (38%), Gaps = 69/394 (17%)
Query: 36 YDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAISGNETQPYPAFT 95
Y Y D D+ E KF + R++ G RV L + P ++ N ++ F
Sbjct: 356 YTPAYGDFDFDE--------VKFPNASDMFRRLRDAGFRVTLWVHPFVNYNSSR----FG 403
Query: 96 RGVEDDVFIKYPNDGDIVWGKLYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLK 155
GVE ++F++ P + + A DF W++ + L + + S K
Sbjct: 404 EGVERELFVREPTGRLPALVRWWNGIGAVLDFTHPKARDWFQGHLRRLRS--RYSVASFK 461
Query: 156 FDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDG 215
FD G VS RD S P P + SR ++ LP
Sbjct: 462 FDA-------------GEVSYLPRDFSTYRPLPDPSVWSR----------RYTEMALPFF 498
Query: 216 SLVQHYNVHNLYGWSQTRPTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQ 275
SL ++ R Y++ Q ++ +V S + G+ LG +
Sbjct: 499 SL------------AEVRVGYQS-QNISCFFRLVDRDSVW-------GYDLGLRSLIPAV 538
Query: 276 LKKSIIGSFYFLLFQTGADIC----GFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQ 331
L S++G + L G + E E+ +RW+++ AF P +
Sbjct: 539 LTVSMLGYPFILPDMVGGNAVPQRTAGGDVPERELYIRWLEVAAFMPAMQFSIP------ 592
Query: 332 DPVSWDAAFVNISRNVLQTRYTLL-PYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDID 390
P +DA V I++ R +L+ P L L + G +VRPL D+ ID
Sbjct: 593 -PWRYDAEVVAIAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRID 651
Query: 391 SQFLLGPAFLVSPVLERNARNVTAYFPRARWYDY 424
SQFL+G LV+PVLE + Y P +W Y
Sbjct: 652 SQFLIGDTLLVAPVLEPGKQERDVYLPAGKWRSY 685
Score = 59.7 bits (143), Expect = 2e-08
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Query: 1199 EYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLL-PYLYTL 1257
E E+ +RW+++ AF P + P +D V I++ R +L+ P L L
Sbjct: 570 ERELYIRWLEVAAFMPAMQFSIP-------PWRYDAEVVAIAQKFAALRASLVAPLLLEL 622
Query: 1258 MHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARW 1317
+ G +VRPL D+ IDSQFL+G LV+PVLE + Y P +W
Sbjct: 623 AGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEPGKQERDVYLPAGKW 682
Query: 1318 YDY 1320
Y
Sbjct: 683 RSY 685
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 31.6 bits (70), Expect = 6.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 550 VKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYTVEWSIKIRDEE-KIDCY 602
+ H+ P+ + VT+D K+ II+ + GE T ++ D++ KI C+
Sbjct: 5473 INHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCH 5526
>gi|211058421 zinc finger protein 844 [Homo sapiens]
Length = 666
Score = 31.6 bits (70), Expect = 6.0
Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 24/100 (24%)
Query: 993 FPDVVVNGSLD-WD----SQVELYRAYVAFPDFFRNSTA---KWWKREIEELYNNPQNPE 1044
F DV VN + + W SQ LYR + + RN + KW + IE+ Y NP+N
Sbjct: 6 FEDVAVNFTQEEWSLLDPSQKNLYREVMQ--ETLRNLASIGEKWKDQNIEDQYKNPRNNL 63
Query: 1045 RSLKFDGMWIDMNE------------PSSFVNGAVSPGCR 1072
RSL G +D N P +N SPG +
Sbjct: 64 RSLL--GERVDENTEENHCGETSSQIPDDTLNKKTSPGVK 101
>gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E
subunit [Homo sapiens]
Length = 2270
Score = 31.2 bits (69), Expect = 7.8
Identities = 14/47 (29%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 101 DVFIKYPNDGDIVWGKLYRAYVAFPDFFRNSTAKWWKREIEELYNNP 147
D+ + P D+ GK+Y A + D+++ S K ++++EE N P
Sbjct: 1852 DLLVPMPKASDLTVGKIYAAMMIM-DYYKQSKVKKQRQQLEEQKNAP 1897
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,838,115
Number of Sequences: 37866
Number of extensions: 2891752
Number of successful extensions: 5403
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5240
Number of HSP's gapped (non-prelim): 39
length of query: 1492
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1377
effective length of database: 13,892,928
effective search space: 19130561856
effective search space used: 19130561856
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.