Search of human proteins with 167860116

Search of human proteins with 167860116

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|167860116 geranylgeranyltransferase type 1 beta [Homo
sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167860116 geranylgeranyltransferase type 1 beta [Homo sapiens]     780   0.0  
gi|21359854 RAB geranylgeranyltransferase, beta subunit [Homo sa...   136   4e-32
gi|10835059 farnesyltransferase, CAAX box, beta [Homo sapiens]        115   5e-26
gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens]          31   2.1  
gi|189217876 sal-like 1 isoform b [Homo sapiens]                       29   6.1  
gi|118442837 sal-like 1 isoform a [Homo sapiens]                       29   6.1  
gi|24432026 kelch-like [Homo sapiens]                                  29   6.1  

>gi|167860116 geranylgeranyltransferase type 1 beta [Homo sapiens]
          Length = 377

 Score =  780 bits (2015), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDM 60
           MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDM
Sbjct: 1   MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDM 60

Query: 61  LDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSG 120
           LDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSG
Sbjct: 61  LDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSG 120

Query: 121 HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
           HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC
Sbjct: 121 HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180

Query: 181 ICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240
           ICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF
Sbjct: 181 ICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVF 240

Query: 241 SEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILS 300
           SEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILS
Sbjct: 241 SEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILS 300

Query: 301 TQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQS 360
           TQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQS
Sbjct: 301 TQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQS 360

Query: 361 WKTKDSKQCSENVHIST 377
           WKTKDSKQCSENVHIST
Sbjct: 361 WKTKDSKQCSENVHIST 377


>gi|21359854 RAB geranylgeranyltransferase, beta subunit [Homo
           sapiens]
          Length = 331

 Score =  136 bits (342), Expect = 4e-32
 Identities = 95/317 (29%), Positives = 152/317 (47%), Gaps = 34/317 (10%)

Query: 40  YSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSS 99
           Y   E  R++  ++ L+ +D++  L  +N+++I+ +I S Q          + CG     
Sbjct: 39  YCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQ----------HECG----- 83

Query: 100 YLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDG 159
             GI  +    P         H+  T + +  L +  D ++ ++    +  ++ LQ EDG
Sbjct: 84  --GISASIGHDP---------HLLYTLSAVQILTLY-DSINVIDVNKVVEYVKGLQKEDG 131

Query: 160 SFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESH 219
           SF     G E D RF +CA     +L     ++++KAI ++   M++D G     G ESH
Sbjct: 132 SFAGDIWG-EIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESH 190

Query: 220 GGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQ--QNGYHGRPNKPVDTCYSFWVG 277
            G  +C    L +  +L +V S+     +  W   RQ    G +GRP K  D CYS+WV 
Sbjct: 191 AGQIYCCTGFLAITSQLHQVNSDL----LGWWLCERQLPSGGLNGRPEKLPDVCYSWWVL 246

Query: 278 ATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGI 337
           A+LK++    + + EK RN+IL+ QD   GGFA  P    D  H  FGI GLSL+ E  I
Sbjct: 247 ASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQI 306

Query: 338 CKVHPALNVSTRTSERL 354
             V+P   +     +R+
Sbjct: 307 KPVNPVFCMPEEVLQRV 323


>gi|10835059 farnesyltransferase, CAAX box, beta [Homo sapiens]
          Length = 437

 Score =  115 bits (289), Expect = 5e-26
 Identities = 95/335 (28%), Positives = 150/335 (44%), Gaps = 42/335 (12%)

Query: 17  RLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWI 76
           RL   R++H  + +R L+ L + Y  L+ SR  + ++ L  L++LD        + I  I
Sbjct: 70  RLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLD--------EPIPQI 121

Query: 77  YSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILG 136
            +  V    +       GF G         P + P         H+A TY  ++ L I+G
Sbjct: 122 VATDVCQFLELCQSPEGGFGGG--------PGQYP---------HLAPTYAAVNALCIIG 164

Query: 137 DDLSR--VNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMK 194
            + +   +N+E  L  L +L+  DGSF  +  G E D+R  YCA+ +  + N  +    +
Sbjct: 165 TEEAYDIINREKLLQYLYSLKQPDGSFL-MHVGGEVDVRSAYCAASVASLTNIITPDLFE 223

Query: 195 KAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIM 254
               +I R  +++ G+    G+E+HGG TFCG+A+L ++ K E   + K L +      M
Sbjct: 224 GTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVIL-KRERSLNLKSLLQWVTSRQM 282

Query: 255 RQQNGYHGRPNKPVDTCYSFWVGATLKLLK-----------IFQYTNFEKN--RNYILST 301
           R + G+ GR NK VD CYSFW    L LL               +  F +   + YIL  
Sbjct: 283 RFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMC 342

Query: 302 QDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESG 336
                GG    P    D  H  + + GLS+ +  G
Sbjct: 343 CQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFG 377


>gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens]
          Length = 535

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 105 FNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAV 164
           F+P+ APG A  YDS    +  +G   +  L ++L ++ K+    G       +G    V
Sbjct: 346 FDPNSAPGVARVYDS----VQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANV 401

Query: 165 PEGS 168
           P+GS
Sbjct: 402 PDGS 405


>gi|189217876 sal-like 1 isoform b [Homo sapiens]
          Length = 1227

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 41  SSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSY 100
           SS  TS +T +   L  L  L +  V+N + IIE + S +V   +  S   RCG      
Sbjct: 68  SSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQ-FSQEARCGGASGGK 126

Query: 101 LGIP 104
           L +P
Sbjct: 127 LAVP 130


>gi|118442837 sal-like 1 isoform a [Homo sapiens]
          Length = 1324

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 41  SSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSY 100
           SS  TS +T +   L  L  L +  V+N + IIE + S +V   +  S   RCG      
Sbjct: 165 SSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQ-FSQEARCGGASGGK 223

Query: 101 LGIP 104
           L +P
Sbjct: 224 LAVP 227


>gi|24432026 kelch-like [Homo sapiens]
          Length = 634

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 12/120 (10%)

Query: 24  RHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDII--EWIYSLQV 81
           RH R+FQ  +Q L + ++ L    +    +A++G D  + L+ V + D     W Y   +
Sbjct: 375 RHNRWFQ--IQSLQQEHADLSVCVVGRYIYAVAGRDYHNDLNAVERYDPATNSWAYVAPL 432

Query: 82  L--------PTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLV 133
                     T +      CG RG  YL           T H    G +   + G++ L+
Sbjct: 433 KREVYAHAGATLEGKMYITCGRRGEDYLKETHCYDPGSNTWHTLADGPVRRAWHGMATLL 492


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,125,451
Number of Sequences: 37866
Number of extensions: 665200
Number of successful extensions: 1242
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1226
Number of HSP's gapped (non-prelim): 8
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.