Guide to the Human Genome
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Search of human proteins with 110671314

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110671314 protection of telomeres 1 isoform 4 [Homo sapiens]
         (503 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110671314 protection of telomeres 1 isoform 4 [Homo sapiens]      1021   0.0  
gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]       1021   0.0  
gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    35   0.16 
gi|239756270 PREDICTED: StAR-related lipid transfer (START) doma...    33   0.61 
gi|239750815 PREDICTED: StAR-related lipid transfer (START) doma...    33   0.61 
gi|239745175 PREDICTED: StAR-related lipid transfer (START) doma...    33   0.61 
gi|22726201 inositol polyphosphate multikinase [Homo sapiens]          33   0.61 
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             33   0.79 
gi|7661878 kinesin family member 14 [Homo sapiens]                     32   1.0  
gi|5032223 plexin C1 [Homo sapiens]                                    32   1.8  
gi|116284392 mucin 2 precursor [Homo sapiens]                          31   2.3  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              31   2.3  
gi|40217794 hypothetical protein LOC151050 [Homo sapiens]              30   3.9  

>gi|110671314 protection of telomeres 1 isoform 4 [Homo sapiens]
          Length = 503

 Score = 1021 bits (2641), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF 60
           MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF
Sbjct: 1   MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF 60

Query: 61  PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM 120
           PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM
Sbjct: 61  PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM 120

Query: 121 NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP 180
           NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP
Sbjct: 121 NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP 180

Query: 181 DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP 240
           DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP
Sbjct: 181 DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP 240

Query: 241 RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG 300
           RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG
Sbjct: 241 RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG 300

Query: 301 RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP 360
           RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP
Sbjct: 301 RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP 360

Query: 361 FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG 420
           FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG
Sbjct: 361 FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG 420

Query: 421 TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN 480
           TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN
Sbjct: 421 TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN 480

Query: 481 VTNGTDNQICYQIFDTTVAEDVI 503
           VTNGTDNQICYQIFDTTVAEDVI
Sbjct: 481 VTNGTDNQICYQIFDTTVAEDVI 503


>gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]
          Length = 634

 Score = 1021 bits (2641), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF 60
           MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF
Sbjct: 132 MVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPF 191

Query: 61  PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM 120
           PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM
Sbjct: 192 PSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSM 251

Query: 121 NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP 180
           NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP
Sbjct: 252 NSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEP 311

Query: 181 DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP 240
           DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP
Sbjct: 312 DDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKP 371

Query: 241 RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG 300
           RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG
Sbjct: 372 RRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG 431

Query: 301 RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP 360
           RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP
Sbjct: 432 RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAP 491

Query: 361 FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG 420
           FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG
Sbjct: 492 FLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDG 551

Query: 421 TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN 480
           TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN
Sbjct: 552 TGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYN 611

Query: 481 VTNGTDNQICYQIFDTTVAEDVI 503
           VTNGTDNQICYQIFDTTVAEDVI
Sbjct: 612 VTNGTDNQICYQIFDTTVAEDVI 634


>gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
            [Homo sapiens]
          Length = 1704

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 30/129 (23%)

Query: 72   LEGDLSHIHRLQNLTIDILVYDNH-VHVARSLKVGSFLRIYSLHTKL------------- 117
            ++GD  H+ RLQ LTI  +V +   + V   ++ G  L I+  HTKL             
Sbjct: 1053 VQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHG-HTKLDFTVWHTAIEKAA 1111

Query: 118  --------QSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSD-------VDQLKKDLE 162
                        S+N   + +   +   T YG G + + + N D       ++  KKD  
Sbjct: 1112 GTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDAR 1171

Query: 163  SANLTANQH 171
            S  L A +H
Sbjct: 1172 SFKLRAGKH 1180


>gi|239756270 PREDICTED: StAR-related lipid transfer (START) domain
            containing 9 [Homo sapiens]
          Length = 4614

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 15/118 (12%)

Query: 135  HGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSD---------------VICQSE 179
            H  T    G+  +PE      Q   +LE+A+  A  +S+                +CQ+ 
Sbjct: 2986 HSATDGSVGLIGVPEKKVAEKQASTELEAASFPAGMYSEPLRQFRDSSVGDQNAQVCQTN 3045

Query: 180  PDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRS 237
            P+    + G  +L   E   +    +   H+ LE T  C + K +   + R   +L S
Sbjct: 3046 PEPPATTQGPHTLDLSEGSAESKLVVEPQHECLENTTRCFLEKPQFSTELRDHNRLDS 3103


>gi|239750815 PREDICTED: StAR-related lipid transfer (START) domain
            containing 9 [Homo sapiens]
          Length = 4614

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 15/118 (12%)

Query: 135  HGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSD---------------VICQSE 179
            H  T    G+  +PE      Q   +LE+A+  A  +S+                +CQ+ 
Sbjct: 2986 HSATDGSVGLIGVPEKKVAEKQASTELEAASFPAGMYSEPLRQFRDSSVGDQNAQVCQTN 3045

Query: 180  PDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRS 237
            P+    + G  +L   E   +    +   H+ LE T  C + K +   + R   +L S
Sbjct: 3046 PEPPATTQGPHTLDLSEGSAESKLVVEPQHECLENTTRCFLEKPQFSTELRDHNRLDS 3103


>gi|239745175 PREDICTED: StAR-related lipid transfer (START) domain
            containing 9 [Homo sapiens]
          Length = 4614

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 15/118 (12%)

Query: 135  HGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSD---------------VICQSE 179
            H  T    G+  +PE      Q   +LE+A+  A  +S+                +CQ+ 
Sbjct: 2986 HSATDGSVGLIGVPEKKVAEKQASTELEAASFPAGMYSEPLRQFRDSSVGDQNAQVCQTN 3045

Query: 180  PDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRS 237
            P+    + G  +L   E   +    +   H+ LE T  C + K +   + R   +L S
Sbjct: 3046 PEPPATTQGPHTLDLSEGSAESKLVVEPQHECLENTTRCFLEKPQFSTELRDHNRLDS 3103


>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
          Length = 416

 Score = 33.1 bits (74), Expect = 0.61
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 19/97 (19%)

Query: 46  ASFLLKVWDGTRTPFPSW---RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSL 102
           AS LL V++G+  P  +    R L +  + +G LS          ++L Y+N+ HV  S 
Sbjct: 250 ASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDT--------EVLEYNNNFHVLSST 301

Query: 103 KVG--------SFLRIYSLHTKLQSMNSENQTMLSLE 131
             G        S  ++Y+ H K+ +    +QT L +E
Sbjct: 302 ANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVE 338


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 19   LLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSH 78
            LL+L  V P    + +CQ+ G +    AS L+ +   +  P P+   L Q + +E   SH
Sbjct: 2877 LLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPA-PGLAQPIYIEASSSH 2935

Query: 79   IHRLQNLTIDILV 91
            +   Q L ++ +V
Sbjct: 2936 VTEGQTLDLNCVV 2948


>gi|7661878 kinesin family member 14 [Homo sapiens]
          Length = 1648

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 4/124 (3%)

Query: 213 ERTPLC----AILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDI 268
           ER  LC      L+ K  QQ R  A+++     +  Q+ K    +   LQ+      +D 
Sbjct: 739 ERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDN 798

Query: 269 IFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGT 328
              +      D +L    LY  K  TT   K +  + H ++ +G+L   + C +   GGT
Sbjct: 799 HLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGT 858

Query: 329 LSEI 332
           +S I
Sbjct: 859 VSII 862


>gi|5032223 plexin C1 [Homo sapiens]
          Length = 1568

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 32/144 (22%)

Query: 250 HCPKCHLLQEVPHEGD----------LDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQK 299
           HC  CH LQ    +GD          LDI    GA K P +++    +  SK  TT    
Sbjct: 471 HCGWCHSLQRCTFQGDCVHSENLENWLDI--SSGAKKCPKIQI----IRSSKEKTTVTMV 524

Query: 300 GRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSV----IPVRSGHEDLELL 355
           G              P  ++C++     +  E+C+  ++ N      IP R+ ++D+ ++
Sbjct: 525 G-----------SFSPRHSKCMVK-NVDSSRELCQNKSQPNRTCTCSIPTRATYKDVSVV 572

Query: 356 DLSAPFLIQGTIHHYGCKQCSSLR 379
           ++   F        +    CSSL+
Sbjct: 573 NVMFSFGSWNLSDRFNFTNCSSLK 596


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 11/134 (8%)

Query: 103 KVGSFLRIYSLHTKLQSMNSENQTMLSLEF----HLHGGTSYGRGIRVLPESNSDVDQLK 158
           K  ++ ++YS        N E+  ML L+     H  G      G++   E  SD   L 
Sbjct: 130 KSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLF 188

Query: 159 KDLESANLTANQHSDVICQSEPDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLC 218
             LE  N+      DV+C+   ++  P+S S    E ER   L+A    D Q L   PL 
Sbjct: 189 SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERL--LTAEAFADCQDL--VPLE 244

Query: 219 AILKQKAPQQYRIR 232
             L  +A QQ R R
Sbjct: 245 PYL--RACQQDRCR 256


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 11/134 (8%)

Query: 103 KVGSFLRIYSLHTKLQSMNSENQTMLSLEF----HLHGGTSYGRGIRVLPESNSDVDQLK 158
           K  ++ ++YS        N E+  ML L+     H  G      G++   E  SD   L 
Sbjct: 130 KSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLF 188

Query: 159 KDLESANLTANQHSDVICQSEPDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLC 218
             LE  N+      DV+C+   ++  P+S S    E ER   L+A    D Q L   PL 
Sbjct: 189 SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERL--LTAEAFADCQDL--VPLE 244

Query: 219 AILKQKAPQQYRIR 232
             L  +A QQ R R
Sbjct: 245 PYL--RACQQDRCR 256


>gi|40217794 hypothetical protein LOC151050 [Homo sapiens]
          Length = 987

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 11/128 (8%)

Query: 109 RIYSLHTKLQSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLE------ 162
           R+ S  T LQ+  S+ +  +     +H      +GI VL E     D LKK ++      
Sbjct: 377 RVGSRWTWLQAQISDLECKIQQLTDIHRQIRASKGIVVLEECQLPKDILKKQMQFADQAA 436

Query: 163 SANLTANQHSDVICQSE-PDDSF---PSSGSVSLYEVER-CQQLSATILTDHQYLERTPL 217
           S N+  N      CQ   P+  F   PSS ++ L  +E+   QL+  I +    L  +P 
Sbjct: 437 SLNILGNPQVPQECQDPVPEQDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPT 496

Query: 218 CAILKQKA 225
            + L  K+
Sbjct: 497 SSPLSSKS 504


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,533,545
Number of Sequences: 37866
Number of extensions: 857570
Number of successful extensions: 1680
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1672
Number of HSP's gapped (non-prelim): 16
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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