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Search of human proteins with 167001643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167001643 mevalonate kinase [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167001643 mevalonate kinase [Homo sapiens] 786 0.0
gi|4557769 mevalonate kinase [Homo sapiens] 786 0.0
gi|4503895 galactokinase 1 [Homo sapiens] 48 1e-05
gi|48527957 galactokinase 2 isoform 2 [Homo sapiens] 37 0.041
gi|4503897 galactokinase 2 isoform 1 [Homo sapiens] 37 0.041
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 32 1.3
gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens] 31 1.7
gi|122114658 hypothetical protein LOC23053 [Homo sapiens] 31 2.2
gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isofor... 30 5.0
gi|154354996 inositol 1,4,5-triphosphate receptor, type 1 isofor... 30 5.0
gi|41399285 chaperonin [Homo sapiens] 29 6.5
gi|31542947 chaperonin [Homo sapiens] 29 6.5
gi|63175654 fucokinase [Homo sapiens] 29 6.5
gi|161019170 mucin 5AC [Homo sapiens] 29 8.5
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 29 8.5
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 29 8.5
>gi|167001643 mevalonate kinase [Homo sapiens]
Length = 396
Score = 786 bits (2029), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC
Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE
Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP
Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM
Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396
TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL
Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396
>gi|4557769 mevalonate kinase [Homo sapiens]
Length = 396
Score = 786 bits (2029), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR
Sbjct: 1 MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR 60
Query: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC
Sbjct: 61 AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC 120
Query: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE
Sbjct: 121 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 180
Query: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP
Sbjct: 181 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 240
Query: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM
Sbjct: 241 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM 300
Query: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL
Sbjct: 301 NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL 360
Query: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396
TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL
Sbjct: 361 TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396
>gi|4503895 galactokinase 1 [Homo sapiens]
Length = 392
Score = 48.1 bits (113), Expect = 1e-05
Identities = 96/374 (25%), Positives = 140/374 (37%), Gaps = 80/374 (21%)
Query: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65
L VSAPG+V L GEH + + L ++L L T L P +G V L + G A +
Sbjct: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEG---ADEPQ 86
Query: 66 RLQ-SLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQR 124
RLQ L T+ Q + T +K V + Y
Sbjct: 87 RLQFPLPTA---QRSLEPGTPRWANYVKGV------------------IQYY-----PAA 120
Query: 125 ALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLEL 184
LP VV S +P G GL SSA+ V L +C + G R
Sbjct: 121 PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPD------SGTIAAR-------- 166
Query: 185 INKWAFQGERMIHGNPSGV-DNAVSTWGGALRYHQGKISSLKRS------PALQILLTNT 237
+ Q E G P G+ D +S G SL+ S P L +L+TN+
Sbjct: 167 -AQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNS 225
Query: 238 KVPRNTRALVAGVRNRLLKFPEIVAPL----LTSIDAISLECER-------------VLG 280
V + + VR R + E+ L L + LE R V+G
Sbjct: 226 NVRHSLASSEYPVRRR--QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVG 283
Query: 281 EMGEAPAPEQYLVLEE-------LIDMNQHHLNALGVGHASLDQLCQVTRA-RGLH-SKL 331
E+ L + +++ ++ + V LDQL + A G++ S++
Sbjct: 284 EIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRM 343
Query: 332 TGAGGGGCGITLLK 345
TG G GGC +TLL+
Sbjct: 344 TGGGFGGCTVTLLE 357
>gi|48527957 galactokinase 2 isoform 2 [Homo sapiens]
Length = 447
Score = 36.6 bits (83), Expect = 0.041
Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 7/63 (11%)
Query: 287 APEQYL-VLEELIDMNQHHLNALGVGHAS---LDQLCQVTRARGLH-SKLTGAGGGGCGI 341
APE + +L EL MNQ H++ + S LDQL + R G S+LTGAG GGC +
Sbjct: 341 APENMVQLLGEL--MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTV 398
Query: 342 TLL 344
+++
Sbjct: 399 SMV 401
>gi|4503897 galactokinase 2 isoform 1 [Homo sapiens]
Length = 458
Score = 36.6 bits (83), Expect = 0.041
Identities = 26/63 (41%), Positives = 37/63 (58%), Gaps = 7/63 (11%)
Query: 287 APEQYL-VLEELIDMNQHHLNALGVGHAS---LDQLCQVTRARGLH-SKLTGAGGGGCGI 341
APE + +L EL MNQ H++ + S LDQL + R G S+LTGAG GGC +
Sbjct: 352 APENMVQLLGEL--MNQSHMSCRDMYECSCPELDQLVDICRKFGAQGSRLTGAGWGGCTV 409
Query: 342 TLL 344
+++
Sbjct: 410 SMV 412
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 31.6 bits (70), Expect = 1.3
Identities = 14/35 (40%), Positives = 20/35 (57%)
Query: 201 SGVDNAVSTWGGALRYHQGKISSLKRSPALQILLT 235
+G D V W G+L +G + SL SPAL + L+
Sbjct: 1902 AGEDGKVQVWSGSLGRPRGHLGSLSLSPALSVALS 1936
>gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]
Length = 786
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 27 VALAVSLNLRTFL---RLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTP 83
+ + ++L++R + ++P N K + L I +A +A +S ++G+VTT
Sbjct: 427 IGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEGEVTTM 486
Query: 84 TSEQVEKLKEVAGLPDD 100
E + LKE+ P D
Sbjct: 487 NHEDLSLLKEILKRPVD 503
>gi|122114658 hypothetical protein LOC23053 [Homo sapiens]
Length = 1842
Score = 30.8 bits (68), Expect = 2.2
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 316 DQLCQVTR-----ARGLHSKLTGAGGGGCGITLLKPGLEQPEVE-ATKQALTSCGFDCLE 369
+ LCQ R + G +S G GGGG G T ++ GL P VE + KQ F+ +E
Sbjct: 35 ESLCQNWRGWRKQSAGPNSPTGGGGGGGSGGTRMRDGLVIPLVELSAKQVAFHIPFEVVE 94
>gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isoform 1
[Homo sapiens]
Length = 2710
Score = 29.6 bits (65), Expect = 5.0
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 275 CERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVT-RARGLHSKLTG 333
C GE +PAP + LV E + ++ H +C VT + GL S
Sbjct: 2457 CRVESGENCSSPAPREELVPAEETEQDKEHT-------CETLLMCIVTVLSHGLRS---- 2505
Query: 334 AGGGGCGITLLKPGLEQP 351
GGG G L KP E+P
Sbjct: 2506 --GGGVGDVLRKPSKEEP 2521
>gi|154354996 inositol 1,4,5-triphosphate receptor, type 1 isoform 2
[Homo sapiens]
Length = 2695
Score = 29.6 bits (65), Expect = 5.0
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 275 CERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVT-RARGLHSKLTG 333
C GE +PAP + LV E + ++ H +C VT + GL S
Sbjct: 2442 CRVESGENCSSPAPREELVPAEETEQDKEHT-------CETLLMCIVTVLSHGLRS---- 2490
Query: 334 AGGGGCGITLLKPGLEQP 351
GGG G L KP E+P
Sbjct: 2491 --GGGVGDVLRKPSKEEP 2506
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 29.3 bits (64), Expect = 6.5
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 18/113 (15%)
Query: 4 EVLLVSAPG---------KVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLP 54
+V+ V APG K + V G+ L ++L +QPH GKV +
Sbjct: 296 QVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLE-----DVQPHDLGKVGEVIV 350
Query: 55 N----IGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAV 103
+ +K D A+++ +EQ DVTT E+ + + +A L D AV
Sbjct: 351 TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAV 403
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 29.3 bits (64), Expect = 6.5
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 18/113 (15%)
Query: 4 EVLLVSAPG---------KVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLP 54
+V+ V APG K + V G+ L ++L +QPH GKV +
Sbjct: 296 QVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLE-----DVQPHDLGKVGEVIV 350
Query: 55 N----IGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAV 103
+ +K D A+++ +EQ DVTT E+ + + +A L D AV
Sbjct: 351 TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAV 403
>gi|63175654 fucokinase [Homo sapiens]
Length = 1084
Score = 29.3 bits (64), Expect = 6.5
Identities = 13/28 (46%), Positives = 19/28 (67%)
Query: 130 DIVVWSELPPGAGLGSSAAYSVCLAAAL 157
++ WSELP G+GLG+S+ + AAL
Sbjct: 827 ELHTWSELPHGSGLGTSSILAGTALAAL 854
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 28.9 bits (63), Expect = 8.5
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 300 MNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGIT 342
++ H L V SL+ ++ RARG+ S GA GG C +T
Sbjct: 5653 ISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLT 5695
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 28.9 bits (63), Expect = 8.5
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 300 MNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGIT 342
++ H L V SL+ ++ RARG+ S GA GG C +T
Sbjct: 5319 ISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLT 5361
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 4/37 (10%)
Query: 135 SELPPGAGLGSSAAYSVCLAAA----LLTVCEEIPNP 167
S LP G GLGS+AA S + AA LL +P+P
Sbjct: 1155 SSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDP 1191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,032,242
Number of Sequences: 37866
Number of extensions: 753646
Number of successful extensions: 1650
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1637
Number of HSP's gapped (non-prelim): 25
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.