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Search of human proteins with 157674356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157674356 nexin-related serine protease inhibitor [Homo
sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157674356 nexin-related serine protease inhibitor [Homo sapiens] 860 0.0
gi|211904156 plasminogen activator inhibitor type 1, member 2 is... 188 7e-48
gi|211904154 plasminogen activator inhibitor type 1, member 2 is... 188 7e-48
gi|211904152 plasminogen activator inhibitor type 1, member 2 is... 188 7e-48
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] 188 9e-48
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso... 187 2e-47
gi|170295807 neuroserpin precursor [Homo sapiens] 180 2e-45
gi|4826904 neuroserpin precursor [Homo sapiens] 180 2e-45
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 163 2e-40
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 158 1e-38
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 152 6e-37
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 149 5e-36
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 143 3e-34
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 140 2e-33
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 137 2e-32
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 136 3e-32
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 136 3e-32
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 134 2e-31
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 134 2e-31
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 130 2e-30
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 130 3e-30
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 126 3e-29
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 124 2e-28
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 123 3e-28
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 123 3e-28
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 122 6e-28
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 122 8e-28
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 119 4e-27
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 119 4e-27
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 119 4e-27
>gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]
Length = 424
Score = 860 bits (2221), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP
Sbjct: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
Query: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG
Sbjct: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
Query: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVS 180
TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVS
Sbjct: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVS 180
Query: 181 AAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTA 240
AAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTA
Sbjct: 181 AAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTA 240
Query: 241 GHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPR 300
GHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPR
Sbjct: 241 GHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPR 300
Query: 301 FRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASG 360
FRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASG
Sbjct: 301 FRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASG 360
Query: 361 ATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRIQIIYQCLSSNKGSFVHYPLKN 420
ATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRIQIIYQCLSSNKGSFVHYPLKN
Sbjct: 361 ATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRIQIIYQCLSSNKGSFVHYPLKN 420
Query: 421 KHSF 424
KHSF
Sbjct: 421 KHSF 424
>gi|211904156 plasminogen activator inhibitor type 1, member 2
isoform c precursor [Homo sapiens]
Length = 409
Score = 188 bits (478), Expect = 7e-48
Identities = 125/400 (31%), Positives = 192/400 (48%), Gaps = 11/400 (2%)
Query: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
+P FL+ S C N E L + + ++ + R N VISP G++
Sbjct: 17 LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 73
Query: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
L +LQ GA+G T +QLA + Y V+ V L + + + + +A ++FV+
Sbjct: 74 LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 131
Query: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179
+ + FV + + +P S + ET + P + +
Sbjct: 132 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 186
Query: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239
+LVLV+ + F+G W+ RF +T+ F A G QVPM+ Q + G
Sbjct: 187 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 246
Query: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299
+ELPY G ++S+ + LP + TPLS I PH++ TI W + + R+ V LP
Sbjct: 247 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 306
Query: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKAS 359
+F Q +LK L G+TD+FD KAN I+ + +VS + KAKIEV E+GTKAS
Sbjct: 307 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS 366
Query: 360 GATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399
AT +L+ RS P F DRPF++F+R TG +F +I
Sbjct: 367 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 406
>gi|211904154 plasminogen activator inhibitor type 1, member 2
isoform b precursor [Homo sapiens]
Length = 397
Score = 188 bits (478), Expect = 7e-48
Identities = 125/400 (31%), Positives = 192/400 (48%), Gaps = 11/400 (2%)
Query: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
+P FL+ S C N E L + + ++ + R N VISP G++
Sbjct: 5 LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 61
Query: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
L +LQ GA+G T +QLA + Y V+ V L + + + + +A ++FV+
Sbjct: 62 LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 119
Query: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179
+ + FV + + +P S + ET + P + +
Sbjct: 120 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 174
Query: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239
+LVLV+ + F+G W+ RF +T+ F A G QVPM+ Q + G
Sbjct: 175 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 234
Query: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299
+ELPY G ++S+ + LP + TPLS I PH++ TI W + + R+ V LP
Sbjct: 235 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 294
Query: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKAS 359
+F Q +LK L G+TD+FD KAN I+ + +VS + KAKIEV E+GTKAS
Sbjct: 295 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS 354
Query: 360 GATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399
AT +L+ RS P F DRPF++F+R TG +F +I
Sbjct: 355 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 394
>gi|211904152 plasminogen activator inhibitor type 1, member 2
isoform b precursor [Homo sapiens]
Length = 397
Score = 188 bits (478), Expect = 7e-48
Identities = 125/400 (31%), Positives = 192/400 (48%), Gaps = 11/400 (2%)
Query: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
+P FL+ S C N E L + + ++ + R N VISP G++
Sbjct: 5 LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 61
Query: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
L +LQ GA+G T +QLA + Y V+ V L + + + + +A ++FV+
Sbjct: 62 LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 119
Query: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179
+ + FV + + +P S + ET + P + +
Sbjct: 120 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 174
Query: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239
+LVLV+ + F+G W+ RF +T+ F A G QVPM+ Q + G
Sbjct: 175 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 234
Query: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299
+ELPY G ++S+ + LP + TPLS I PH++ TI W + + R+ V LP
Sbjct: 235 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 294
Query: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKAS 359
+F Q +LK L G+TD+FD KAN I+ + +VS + KAKIEV E+GTKAS
Sbjct: 295 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKAS 354
Query: 360 GATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399
AT +L+ RS P F DRPF++F+R TG +F +I
Sbjct: 355 AATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 394
>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
Length = 402
Score = 188 bits (477), Expect = 9e-48
Identities = 116/371 (31%), Positives = 189/371 (50%), Gaps = 5/371 (1%)
Query: 29 LKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKR 88
L ++F + ++Q VA + N V SP GV+ L +LQ G T QQ+ A+G+ + DK
Sbjct: 34 LASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKG 93
Query: 89 VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPN 148
+ L +Y L E+ ++FVQ L F+ H S+++ D SE
Sbjct: 94 MAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVE 153
Query: 149 STAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQ 208
++ T G S G +Q++ +LVLV+ + F G W+ F + T
Sbjct: 154 RARFIINDWVKTHTKGM-ISNLLGKGAVDQLT----RLVLVNALYFNGQWKTPFPDSSTH 208
Query: 209 ILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDT 268
F + G + VPMM QT + NY +F GH +LELPY G +S+F+ P +K+
Sbjct: 209 RRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEV 268
Query: 269 PLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKAN 328
PLS + L+A I W ++ R + LP+F ++ + +L+ L + G+TD+F +A+
Sbjct: 269 PLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQAD 328
Query: 329 LKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFIYFLREP 388
+S Q+ +V++A+ K KIEV E GT AS +TA+++ R DRPF++ +R
Sbjct: 329 FTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHN 388
Query: 389 NTGITVFFDRI 399
TG +F ++
Sbjct: 389 PTGTVLFMGQV 399
>gi|24307907 plasminogen activator inhibitor type 1, member 2
isoform a precursor [Homo sapiens]
Length = 398
Score = 187 bits (474), Expect = 2e-47
Identities = 126/401 (31%), Positives = 193/401 (48%), Gaps = 12/401 (2%)
Query: 1 MPPFLITLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLP 60
+P FL+ S C N E L + + ++ + R N VISP G++
Sbjct: 5 LPLFLLASVTLPSICSHFNPLSLEE---LGSNTGIQVFNQIVKSRPHDNIVISPHGIASV 61
Query: 61 LEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVG 120
L +LQ GA+G T +QLA + Y V+ V L + + + + +A ++FV+
Sbjct: 62 LGMLQLGADGRTKKQLAMVMRYGVNG--VGKILKKINKAIVSKKNKDIVTVANAVFVKNA 119
Query: 121 TPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSE-GPGGWPWEQV 179
+ + FV + + +P S + ET + P + +
Sbjct: 120 SEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSP-----DLI 174
Query: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239
+LVLV+ + F+G W+ RF +T+ F A G QVPM+ Q + G
Sbjct: 175 DGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAP 234
Query: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299
+ELPY G ++S+ + LP + TPLS I PH++ TI W + + R+ V LP
Sbjct: 235 NDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILP 294
Query: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGI-SGQDGFYVSEAIHKAKIEVLEEGTKA 358
+F Q +LK L G+TD+FD KAN I +G + +VS + KAKIEV E+GTKA
Sbjct: 295 KFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKA 354
Query: 359 SGATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399
S AT +L+ RS P F DRPF++F+R TG +F +I
Sbjct: 355 SAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQI 395
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 180 bits (456), Expect = 2e-45
Identities = 107/378 (28%), Positives = 203/378 (53%), Gaps = 21/378 (5%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY-TVHDKRVK 90
+ ++++Y + A + N + SP ++L + +++ GA+GST +++ ++GY ++ +
Sbjct: 28 DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
Query: 91 DFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNST 150
FL + M++A SLFVQ G ++ F++ + + N+++ D S+ +
Sbjct: 88 SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAV 147
Query: 151 AIQTSEGASRETAGGGPSEGPGGWPWEQVSA----AFAQLVLVSTMSFQGTWRKRFSSTD 206
A ++ T + VS A L L++ + F+G W+ +F +
Sbjct: 148 ANYINKWVENNT---------NNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
Query: 207 TQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVG---VLELPYLGSAVSLFLVLP 263
T+ FT +Q+PMM+Q E YG+F D + G VLE+PY G +S+ LVL
Sbjct: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
Query: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
R ++ PL+ +EP + A + W S+++ +++V+LPRF ++ + +LK +L + G+T++F
Sbjct: 259 R-QEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFI 317
Query: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI--PIFKADRPF 381
ANL G+S ++S+AIHK+ +EV EEG++A+ + ++ + R + P D PF
Sbjct: 318 K-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPF 376
Query: 382 IYFLREPNTGITVFFDRI 399
+ +R TG +F R+
Sbjct: 377 FFLIRNRRTGTILFMGRV 394
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 180 bits (456), Expect = 2e-45
Identities = 107/378 (28%), Positives = 203/378 (53%), Gaps = 21/378 (5%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY-TVHDKRVK 90
+ ++++Y + A + N + SP ++L + +++ GA+GST +++ ++GY ++ +
Sbjct: 28 DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
Query: 91 DFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNST 150
FL + M++A SLFVQ G ++ F++ + + N+++ D S+ +
Sbjct: 88 SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAV 147
Query: 151 AIQTSEGASRETAGGGPSEGPGGWPWEQVSA----AFAQLVLVSTMSFQGTWRKRFSSTD 206
A ++ T + VS A L L++ + F+G W+ +F +
Sbjct: 148 ANYINKWVENNT---------NNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPEN 198
Query: 207 TQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVG---VLELPYLGSAVSLFLVLP 263
T+ FT +Q+PMM+Q E YG+F D + G VLE+PY G +S+ LVL
Sbjct: 199 TRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS 258
Query: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
R ++ PL+ +EP + A + W S+++ +++V+LPRF ++ + +LK +L + G+T++F
Sbjct: 259 R-QEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFI 317
Query: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI--PIFKADRPF 381
ANL G+S ++S+AIHK+ +EV EEG++A+ + ++ + R + P D PF
Sbjct: 318 K-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPF 376
Query: 382 IYFLREPNTGITVFFDRI 399
+ +R TG +F R+
Sbjct: 377 FFLIRNRRTGTILFMGRV 394
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 163 bits (413), Expect = 2e-40
Identities = 116/381 (30%), Positives = 190/381 (49%), Gaps = 22/381 (5%)
Query: 31 TEFALHLYQSVAACRNET-NFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRV 89
+ FA YQ +A +N+ N +SP +S + + GA T QQL + + ++
Sbjct: 88 SRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKT 147
Query: 90 KDFLHAVYATLPT-----SSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADL 144
D +H +A L +++ +++ A LF + + + + L+P D
Sbjct: 148 SDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDF 207
Query: 145 SE-PNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFS 203
E + ++ S +T G P + LVLV+T+ F+G W+ +FS
Sbjct: 208 KENAEQSRAAINKWVSNKTEGRITDVIPS-----EAINELTVLVLVNTIYFKGLWKSKFS 262
Query: 204 STDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLP 263
+T+ F A G MM+Q + Y + + G QV LELP+ G +++ L+LP
Sbjct: 263 PENTRKELFYKADGESCSASMMYQEGKFRYRRVAE--GTQV--LELPFKGDDITMVLILP 318
Query: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
+ + + L+ +E LT + W L + V +PRFRI++ F+LK L G+ DLF
Sbjct: 319 KPEKS-LAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFS 377
Query: 324 PLKANLKGI--SGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIP---IFKAD 378
P K+ L GI G+D YVS+A HKA +EV EEG++A+ +TA+++ RS P FKA+
Sbjct: 378 PEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKAN 437
Query: 379 RPFIYFLREPNTGITVFFDRI 399
RPF+ F+RE +F R+
Sbjct: 438 RPFLVFIREVPLNTIIFMGRV 458
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 158 bits (399), Expect = 1e-38
Identities = 109/405 (26%), Positives = 195/405 (48%), Gaps = 30/405 (7%)
Query: 7 TLFLFHSCCLRANGHLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQF 66
T+FL+ L TEFA+ LYQ V+ + N + SP G++L LE++Q
Sbjct: 3 TIFLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQL 61
Query: 67 GAEGSTGQQLADALGYTVHDKRVKDF-LHAVYATLPTSSQGTEMELACSLFVQVGTPLSP 125
GA+G QQ+ L + F L + ++ + Q LA +L++Q G +
Sbjct: 62 GAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKE 121
Query: 126 CFVEHVSWWANSSLEPADLSEPNSTAIQTSEGASRETAG------GGPSEGPGGWPWEQV 179
++ + S+++ D + + A S R+T G G GP
Sbjct: 122 QYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGP-------- 173
Query: 180 SAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT 239
+LVLV+ + F+G W+++F DTQ++ FT G +++PMM YG F ++
Sbjct: 174 ---LTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSES 230
Query: 240 AGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLP 299
+ VLEL Y G SL ++LP + + +E +TA I W + ++ +++ LP
Sbjct: 231 S-LNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQEEEVEISLP 288
Query: 300 RFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKAS 359
RF+++ + + K +L S +T++F +L GI+ YVS+ K E+ E+G++A+
Sbjct: 289 RFKVEQKVDFKDVLYSLNITEIFSG-GCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAA 347
Query: 360 GAT-----ALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399
+T ++ L +S+ F A+ PF++ ++ T +F R+
Sbjct: 348 TSTGIHIPVIMSLAQSQ---FIANHPFLFIMKHNPTESILFMGRV 389
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 152 bits (384), Expect = 6e-37
Identities = 113/383 (29%), Positives = 185/383 (48%), Gaps = 17/383 (4%)
Query: 24 EGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT 83
E ++ T FAL L+ +++ N ISP +S + ++ G G+T QL+ +
Sbjct: 2 EQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 61
Query: 84 VHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPAD 143
++ V ++ A + ++LA L+ + P F+ + L D
Sbjct: 62 TVEE-VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
Query: 144 LSEPNSTAIQT-SEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRF 202
+ A +T ++ +T G P G + +LVLV+ + F+G W+ +F
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASG-----MVDNMTKLVLVNAIYFKGNWKDKF 175
Query: 203 SSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVL 262
T PF V MM+Q + YG +D + VLELPY G +S+ ++L
Sbjct: 176 MKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDL---KCRVLELPYQGEELSMVILL 232
Query: 263 P---RDKDTPLSHIEPHLTASTIHLWTT--SLRRARMDVFLPRFRIQNQFNLKSILNSWG 317
P D+ T L IE LT +H WT +L ++V LPRF+++ + L S L G
Sbjct: 233 PDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLG 292
Query: 318 VTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIP--IF 375
V DLF+ KA+L G+SG ++S+ +HK+ +EV EEGT+A+ ATA + +P F
Sbjct: 293 VQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENF 352
Query: 376 KADRPFIYFLREPNTGITVFFDR 398
AD PF++F+R ++G +F R
Sbjct: 353 TADHPFLFFIRHNSSGSILFLGR 375
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 149 bits (376), Expect = 5e-36
Identities = 112/399 (28%), Positives = 188/399 (47%), Gaps = 38/399 (9%)
Query: 26 MTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVH 85
++ EF L +++ + + N S + L ++ GA G T +QL L H
Sbjct: 4 LSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVL----H 59
Query: 86 DKRVKDFLHAVYATLPTSSQGTEMELACSL-FVQVGTPLSPCFVE-------------HV 131
D L + P SQ + + F Q+ P S C + H
Sbjct: 60 FSHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQ 119
Query: 132 SW------WANSSLEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQ 185
+ W + L+ D + +T G + G + S
Sbjct: 120 QYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSV---- 175
Query: 186 LVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVG 245
+VLV+ + F+G W+ +F +T PF + G + V MM+Q ++ Q+
Sbjct: 176 MVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEP---QMQ 232
Query: 246 VLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTS--LRRARMDVFLPRFRI 303
VLELPY+ + +S+ ++LP L IE L + T H WT+S + ++V LPRF++
Sbjct: 233 VLELPYVNNKLSMIILLPVGIAN-LKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKL 291
Query: 304 QNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATA 363
+ ++ L S+L S GVTDLF+ +KA+L G+S G Y+S+AIHK+ ++V EEGT+A+ AT
Sbjct: 292 ETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATG 351
Query: 364 LLLLKRSRIPI---FKADRPFIYFLREPNTGITVFFDRI 399
+ +S +P+ FKA+ PF++F+R +T +F ++
Sbjct: 352 DSIAVKS-LPMRAQFKANHPFLFFIRHTHTNTILFCGKL 389
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 143 bits (360), Expect = 3e-34
Identities = 107/389 (27%), Positives = 188/389 (48%), Gaps = 32/389 (8%)
Query: 31 TEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY-------- 82
T+F L+Q + E N SP ++ L ++ GA+ +T QQ+ L +
Sbjct: 9 TKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTT 67
Query: 83 ----TVHDKRVKDFLHAVYATLPTSSQGT---EMELACSLFVQVGTPLSPCFVEHVSWWA 135
T H R + H L ++ T E+++A LF + +++ + +
Sbjct: 68 GKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFY 127
Query: 136 NSSLEPADLSE-PNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSF 194
+S+E D + P + + + +T + P G + LVLV+ + F
Sbjct: 128 QTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTT-----LVLVNAIYF 182
Query: 195 QGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGS 254
+G W K+F+ DT+ F + MM Q T ++ +D Q VLE+PY G
Sbjct: 183 KGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDV---QAKVLEIPYKGK 239
Query: 255 AVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTT--SLRRARMDVFLPRFRIQNQFNLKSI 312
+S+ ++LP + D L +E LTA + WT+ ++R R+D+ LPRF+++ ++LK
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDT 298
Query: 313 LNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI 372
L + G+ D+F+ A+L G++G G +S +HKA +EV EEG +A+ ATA++ S
Sbjct: 299 LRTMGMVDIFNG-DADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPT 357
Query: 373 PI---FKADRPFIYFLREPNTGITVFFDR 398
F + PF++F+R+ T +F+ R
Sbjct: 358 STNEEFHCNHPFLFFIRQNKTNSILFYGR 386
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 140 bits (353), Expect = 2e-33
Identities = 102/348 (29%), Positives = 168/348 (48%), Gaps = 20/348 (5%)
Query: 29 LKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY----TV 84
L T+FA LY+ + N SP VS L +L GA T Q+ LG+ T
Sbjct: 65 LNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTP 124
Query: 85 HDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADL 144
+ F H V++ L S+ +++ +LFV+ L F+ +V + + D
Sbjct: 125 ESAIHQGFQHLVHS-LTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDF 183
Query: 145 SEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSS 204
S P+ + + ++T G G +VLV+ + F+ W K F
Sbjct: 184 SNPSIAQARINSHVKKKTQGKVVDIIQG-------LDLLTAMVLVNHIFFKAKWEKPFHP 236
Query: 205 TDTQI-LPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLP 263
T+ PF + + VPMMHQ + +G + VL++ Y G AV+ F++
Sbjct: 237 EYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTEL---NCFVLQMDYKGDAVAFFVLPS 293
Query: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
+ K + +E L+A T+ W+ SL++ ++VF+PRF I +NL++IL G+ ++FD
Sbjct: 294 KGK---MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFD 350
Query: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSR 371
A+ GI+ +D VS+A HKA ++V EEGT+A+ AT + RS+
Sbjct: 351 K-NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSK 397
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 137 bits (344), Expect = 2e-32
Identities = 104/389 (26%), Positives = 188/389 (48%), Gaps = 32/389 (8%)
Query: 31 TEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGY-------- 82
T+F L+Q + E N SP ++ L ++ GA+ +T QQ++ L +
Sbjct: 9 TKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTT 67
Query: 83 ----TVHDKRVKDFLHAVYATLPTSSQGT---EMELACSLFVQVGTPLSPCFVEHVSWWA 135
T H R + H L ++ T E+++A LF + +++ + +
Sbjct: 68 EKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFY 127
Query: 136 NSSLEPADLSE-PNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSF 194
+S+E D + P + + + +T + P G + LVLV+ + F
Sbjct: 128 QTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTT-----LVLVNAIYF 182
Query: 195 QGTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGS 254
+G W +F +T+ F V MM Q N+ +D Q VLE+PY G
Sbjct: 183 KGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDV---QAKVLEIPYKGK 239
Query: 255 AVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTT--SLRRARMDVFLPRFRIQNQFNLKSI 312
+S+ ++LP + D L +E LTA + WT+ ++R +D+ LPRF+++ ++LK
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDT 298
Query: 313 LNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI 372
L + G+ ++F+ A+L G++ G VS+ +HKA +EV EEG +A+ ATA+++++ S
Sbjct: 299 LRTMGMVNIFNG-DADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSP 357
Query: 373 PI---FKADRPFIYFLREPNTGITVFFDR 398
F + PF++F+R+ T +F+ R
Sbjct: 358 STNEEFCCNHPFLFFIRQNKTNSILFYGR 386
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 136 bits (343), Expect = 3e-32
Identities = 107/382 (28%), Positives = 180/382 (47%), Gaps = 38/382 (9%)
Query: 33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDF 92
FA+ L++ + N N SP +S L ++ GA+GST Q++ AL + F
Sbjct: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGF 70
Query: 93 LHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEP----- 147
+ T +Q + A LF + P F E+ + + LE +E
Sbjct: 71 QSLLSEVNRTGTQYL-LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129
Query: 148 ---NSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSS 204
N + +EG E G + +LVLV+ + F+G W ++F
Sbjct: 130 KHINDWVAEKTEGKISEVLDAGTVD------------PLTKLVLVNAIYFKGKWNEQFDR 177
Query: 205 TDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGH----QVGVLELPYLGSAVSLFL 260
T+ G++ + +T ++ + + + G+ VLELPY+ +S+ +
Sbjct: 178 KYTR--------GMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229
Query: 261 VLPRDKDTPLSHIEPHLTASTIHLWTTS--LRRARMDVFLPRFRIQNQFNLKSILNSWGV 318
+LP D +T L+ +E LT WT S L ++++ VFLPR +++ ++L+ L G+
Sbjct: 230 LLP-DDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGM 288
Query: 319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKR-SRI-PIFK 376
D FD KA+ G+S + +S+ HK +EV EEGT+A+ ATA++ R SR+ P F
Sbjct: 289 IDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFC 348
Query: 377 ADRPFIYFLREPNTGITVFFDR 398
AD PF++F+R T +F R
Sbjct: 349 ADHPFLFFIRHHKTNCILFCGR 370
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 136 bits (343), Expect = 3e-32
Identities = 107/382 (28%), Positives = 180/382 (47%), Gaps = 38/382 (9%)
Query: 33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDF 92
FA+ L++ + N N SP +S L ++ GA+GST Q++ AL + F
Sbjct: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGF 70
Query: 93 LHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEP----- 147
+ T +Q + A LF + P F E+ + + LE +E
Sbjct: 71 QSLLSEVNRTGTQYL-LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129
Query: 148 ---NSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSS 204
N + +EG E G + +LVLV+ + F+G W ++F
Sbjct: 130 KHINDWVAEKTEGKISEVLDAGTVD------------PLTKLVLVNAIYFKGKWNEQFDR 177
Query: 205 TDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGH----QVGVLELPYLGSAVSLFL 260
T+ G++ + +T ++ + + + G+ VLELPY+ +S+ +
Sbjct: 178 KYTR--------GMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229
Query: 261 VLPRDKDTPLSHIEPHLTASTIHLWTTS--LRRARMDVFLPRFRIQNQFNLKSILNSWGV 318
+LP D +T L+ +E LT WT S L ++++ VFLPR +++ ++L+ L G+
Sbjct: 230 LLP-DDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGM 288
Query: 319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKR-SRI-PIFK 376
D FD KA+ G+S + +S+ HK +EV EEGT+A+ ATA++ R SR+ P F
Sbjct: 289 IDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFC 348
Query: 377 ADRPFIYFLREPNTGITVFFDR 398
AD PF++F+R T +F R
Sbjct: 349 ADHPFLFFIRHHKTNCILFCGR 370
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 134 bits (337), Expect = 2e-31
Identities = 105/419 (25%), Positives = 189/419 (45%), Gaps = 53/419 (12%)
Query: 24 EGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT 83
E + + T FAL+L++ +A N +SP +S + ++ G+ GST Q+A L +
Sbjct: 2 EDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFN 61
Query: 84 --------------------------------VHDKRVKDFLHAVYATLPTSSQGTE--- 108
+ + D +H+ + +L ++ +
Sbjct: 62 EVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNY 121
Query: 109 -MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQT-SEGASRETAGGG 166
+E LF + ++ + +S + D E A + + +T G
Sbjct: 122 LLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKI 181
Query: 167 PSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMH 226
P+ P G ++VLV+ + F+G W+ F + PF V MM+
Sbjct: 182 PNLLPEG-----SVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMY 236
Query: 227 QTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLP---RDKDTPLSHIEPHLTASTIH 283
++N G +D +LELPY G VS+FL+LP D T L +E +T ++
Sbjct: 237 LREKLNIGYIEDLKAQ---ILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLN 292
Query: 284 LWTTSLRRAR--MDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVS 341
WT+ + A ++V++P+F+++ + L+SIL S G+ D F+ +AN G+S ++ ++S
Sbjct: 293 KWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLS 352
Query: 342 EAIHKAKIEVLEEGTKASGATALLLLKRSRI--PIFKADRPFIYFLREPNTGITVFFDR 398
E H+A ++V EEGT+A+ T ++ R+ P F AD PF++ + T +FF R
Sbjct: 353 EVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGR 411
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 134 bits (337), Expect = 2e-31
Identities = 105/419 (25%), Positives = 189/419 (45%), Gaps = 53/419 (12%)
Query: 24 EGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT 83
E + + T FAL+L++ +A N +SP +S + ++ G+ GST Q+A L +
Sbjct: 2 EDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFN 61
Query: 84 --------------------------------VHDKRVKDFLHAVYATLPTSSQGTE--- 108
+ + D +H+ + +L ++ +
Sbjct: 62 EVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNY 121
Query: 109 -MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAIQT-SEGASRETAGGG 166
+E LF + ++ + +S + D E A + + +T G
Sbjct: 122 LLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKI 181
Query: 167 PSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMH 226
P+ P G ++VLV+ + F+G W+ F + PF V MM+
Sbjct: 182 PNLLPEG-----SVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMY 236
Query: 227 QTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLP---RDKDTPLSHIEPHLTASTIH 283
++N G +D +LELPY G VS+FL+LP D T L +E +T ++
Sbjct: 237 LREKLNIGYIEDLKAQ---ILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLN 292
Query: 284 LWTTSLRRAR--MDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVS 341
WT+ + A ++V++P+F+++ + L+SIL S G+ D F+ +AN G+S ++ ++S
Sbjct: 293 KWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLS 352
Query: 342 EAIHKAKIEVLEEGTKASGATALLLLKRSRI--PIFKADRPFIYFLREPNTGITVFFDR 398
E H+A ++V EEGT+A+ T ++ R+ P F AD PF++ + T +FF R
Sbjct: 353 EVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGR 411
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 130 bits (327), Expect = 2e-30
Identities = 93/366 (25%), Positives = 172/366 (46%), Gaps = 20/366 (5%)
Query: 30 KTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRV 89
+ +F LY+++A+ + SP +S+ L +L GA ST Q+ + LG +
Sbjct: 45 RRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSE 104
Query: 90 KDFLHAVYATLPTSSQ---GTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSE 146
K+ L +Q G ++ L +LF + L FV + + P + +
Sbjct: 105 KELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRD 164
Query: 147 PNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTD 206
Q ++ +++T G + + A +++V+ + F+ W F+
Sbjct: 165 SAGAMKQINDYVAKQTKGKIVD-------LLKNLDSNAVVIMVNYIFFKAKWETSFNHKG 217
Query: 207 TQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDK 266
TQ F V++VPMM + + +Y ++ + VGV PY G+A +LF++ K
Sbjct: 218 TQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGV---PYQGNATALFILPSEGK 274
Query: 267 DTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLK 326
+ +E L+ T+ W ++ +++++LP+F I+ + L+ +L S G++++F
Sbjct: 275 ---MQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTS-H 330
Query: 327 ANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRS---RIPIFKADRPFIY 383
A+L GIS VSE +HKA +EV E GT+A+ AT + RS +RPF+
Sbjct: 331 ADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLM 390
Query: 384 FLREPN 389
F+ + N
Sbjct: 391 FIVDNN 396
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 130 bits (326), Expect = 3e-30
Identities = 104/378 (27%), Positives = 176/378 (46%), Gaps = 28/378 (7%)
Query: 33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDF 92
FA+ L + + N SP +S L ++ GA+G+T Q+A AL +
Sbjct: 11 FAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEED----- 65
Query: 93 LHAVYATLPT--SSQGTE--MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADL---S 145
+H + +L T + GT+ + A LF + F E + ++ L+ +
Sbjct: 66 IHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAA 125
Query: 146 EPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSST 205
E + I T S++T G PG A +LVLV+ + F+G W + F T
Sbjct: 126 EESRKHINT--WVSKKTEGKIEELLPGS-----SIDAETRLVLVNAIYFKGKWNEPFDET 178
Query: 206 DTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRD 265
T+ +PF V MM+Q + +LELPY +SL ++LP D
Sbjct: 179 YTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQ---LLELPYARKELSLLVLLP-D 234
Query: 266 KDTPLSHIEPHLTASTIHLWTTS--LRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
LS +E LT + WT ++ ++V LP+F++Q ++++S+L G+ D F
Sbjct: 235 DGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQ 294
Query: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI---PIFKADRP 380
KA+L +S + +S+ +HK+ +EV EEGT+A+ A++ ++ + P F AD P
Sbjct: 295 QGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHP 354
Query: 381 FIYFLREPNTGITVFFDR 398
F++F+R +F R
Sbjct: 355 FLFFIRHNRANSILFCGR 372
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 126 bits (317), Expect = 3e-29
Identities = 103/384 (26%), Positives = 186/384 (48%), Gaps = 40/384 (10%)
Query: 33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDF 92
FAL+L +++ N N SP +S L ++ GA+G+T Q+A L + +
Sbjct: 11 FALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF--NKSGGGGD 67
Query: 93 LHAVYATLPT--SSQGTE--MELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEP- 147
+H + +L T + GT+ + +A LF + F + + + +E D
Sbjct: 68 IHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAV 127
Query: 148 -------NSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRK 200
N+ + +EG E G + +LVLV+ + F+G W +
Sbjct: 128 EKSRKHINTWVAEKTEGKIAELLSPGSVD------------PLTRLVLVNAVYFRGNWDE 175
Query: 201 RFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQV--GVLELPYLGSAVSL 258
+F +T+ F + V MM + + F+ T ++ +L LPY+G +++
Sbjct: 176 QFDKENTEERLFKVSKNEEKPVQMMFKQST-----FKKTYIGEIFTQILVLPYVGKELNM 230
Query: 259 FLVLPRDKDTPLSHIEPHLTASTIHLWTT--SLRRARMDVFLPRFRIQNQFNLKSILNSW 316
++LP D+ T L +E LT WT + ++V LPRF+++ ++++S+L +
Sbjct: 231 IIMLP-DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNL 289
Query: 317 GVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSR--IPI 374
G+TD F+ KA+ G+S Q +S+ +HK+ +EV EEGT+A+ ATA +++ R +P
Sbjct: 290 GMTDAFELGKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPR 348
Query: 375 FKADRPFIYFLREPNTGITVFFDR 398
F AD PF++F++ T +F R
Sbjct: 349 FCADHPFLFFIQHSKTNGILFCGR 372
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 124 bits (310), Expect = 2e-28
Identities = 98/381 (25%), Positives = 182/381 (47%), Gaps = 23/381 (6%)
Query: 25 GMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTV 84
G+ +FA LY+ + A + N ISP +S+ L +L G G T QL LG+ +
Sbjct: 38 GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 97
Query: 85 HDKRVKDF------LHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSS 138
++ + LH ++A TS EM + +LF+ L F + + S
Sbjct: 98 TERSETEIHQGFQHLHQLFAKSDTS---LEMTMGNALFLDGSLELLESFSADIKHYYESE 154
Query: 139 LEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTW 198
+ + + + + Q + +T G G + A LVLV+ + F+GTW
Sbjct: 155 VLAMNFQDWATASRQINSYVKNKTQGKIVDLFSG-------LDSPAILVLVNYIFFKGTW 207
Query: 199 RKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSL 258
+ F T+ F V++VPMM Q++ ++Y A ++++ Y+G+ ++
Sbjct: 208 TQPFDLASTREENFYVDETTVVKVPMMLQSSTISY---LHDAELPCQLVQMNYVGNG-TV 263
Query: 259 FLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGV 318
F +LP DK ++ + L+ TI+ W+ L +++D+++P+ I ++L +L G+
Sbjct: 264 FFILP-DKG-KMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGI 321
Query: 319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKAD 378
DLF +AN I+ S+ +HKA +++ EEG +G+T + L S+ I + +
Sbjct: 322 ADLFTN-QANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFN 380
Query: 379 RPFIYFLREPNTGITVFFDRI 399
+PFI + + T ++F R+
Sbjct: 381 QPFIIMIFDHFTWSSLFLARV 401
>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 123 bits (309), Expect = 3e-28
Identities = 96/371 (25%), Positives = 179/371 (48%), Gaps = 28/371 (7%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADAL------GY--- 82
EF +L++ + + N S + L +++ GA+ + Q+ L GY
Sbjct: 10 EFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNS 69
Query: 83 TVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPA 142
+ ++ L V++ + S + ++ + LF + ++E ++ +E
Sbjct: 70 SNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERV 129
Query: 143 DLSEP-NSTAIQTSEGASRETAGGGPSE-GPGGWPWEQVSAAFAQLVLVSTMSFQGTWRK 200
D + T ++ ET G + G GG ++ A +VLV+ + F+G W+
Sbjct: 130 DFTNHLEDTRRNINKWVENETHGKIKNVIGEGG------ISSSAVMVLVNAVYFKGKWQS 183
Query: 201 RFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFL 260
F+ ++T F V MMHQ + N +D + + +LEL Y G +++++
Sbjct: 184 AFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPS---MKILELRYNGG-INMYV 239
Query: 261 VLPRDKDTPLSHIEPHLTASTIHLWTTSLRRAR--MDVFLPRFRIQNQFNLKSILNSWGV 318
+LP + LS IE LT + WT R ++VF P+F+I+ + +K L + G+
Sbjct: 240 LLP---ENDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGL 296
Query: 319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRS--RIPIFK 376
D+FD KA+L GI+ Y+S +HK+ IEV EEGT+A+ AT ++++ + +F+
Sbjct: 297 KDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFR 356
Query: 377 ADRPFIYFLRE 387
AD PF++ +R+
Sbjct: 357 ADHPFLFVIRK 367
>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 123 bits (309), Expect = 3e-28
Identities = 96/371 (25%), Positives = 179/371 (48%), Gaps = 28/371 (7%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADAL------GY--- 82
EF +L++ + + N S + L +++ GA+ + Q+ L GY
Sbjct: 10 EFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNS 69
Query: 83 TVHDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPA 142
+ ++ L V++ + S + ++ + LF + ++E ++ +E
Sbjct: 70 SNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERV 129
Query: 143 DLSEP-NSTAIQTSEGASRETAGGGPSE-GPGGWPWEQVSAAFAQLVLVSTMSFQGTWRK 200
D + T ++ ET G + G GG ++ A +VLV+ + F+G W+
Sbjct: 130 DFTNHLEDTRRNINKWVENETHGKIKNVIGEGG------ISSSAVMVLVNAVYFKGKWQS 183
Query: 201 RFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFL 260
F+ ++T F V MMHQ + N +D + + +LEL Y G +++++
Sbjct: 184 AFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPS---MKILELRYNGG-INMYV 239
Query: 261 VLPRDKDTPLSHIEPHLTASTIHLWTTSLRRAR--MDVFLPRFRIQNQFNLKSILNSWGV 318
+LP + LS IE LT + WT R ++VF P+F+I+ + +K L + G+
Sbjct: 240 LLP---ENDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGL 296
Query: 319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRS--RIPIFK 376
D+FD KA+L GI+ Y+S +HK+ IEV EEGT+A+ AT ++++ + +F+
Sbjct: 297 KDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFR 356
Query: 377 ADRPFIYFLRE 387
AD PF++ +R+
Sbjct: 357 ADHPFLFVIRK 367
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 122 bits (306), Expect = 6e-28
Identities = 108/380 (28%), Positives = 178/380 (46%), Gaps = 29/380 (7%)
Query: 31 TEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVK 90
T FAL LY+ +AA N SP +S L +L GA+ +T + + LG+ + +
Sbjct: 55 TNFALRLYKELAADA-PGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEA 113
Query: 91 DF---LHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEP 147
D ++ TL S E+++ SLF+ +++ + + A+ ++
Sbjct: 114 DIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173
Query: 148 NSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQ---LVLVSTMSFQGTWRKRFSS 204
+T Q ++ R+T G P F+Q +VL + + F+ W+ FS
Sbjct: 174 VTTGRQINDYLRRQTYGQVVDCLP----------EFSQDTFMVLANYIFFKAKWKHPFSR 223
Query: 205 TDTQILP-FTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLP 263
TQ F LQVPMMHQ + QD A VL++ Y G+A++L LVLP
Sbjct: 224 YQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLA---CTVLQIEYRGNALAL-LVLP 279
Query: 264 RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFD 323
+ +E L T+ W L + +D+ LPRF I +NL+ IL G+T++ +
Sbjct: 280 --DPGKMKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILN 337
Query: 324 PLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALL----LLKRSRIPIFKADR 379
L+A+ G++GQ +S+ HKA +++ E+GT+A A+ LL L P +R
Sbjct: 338 -LEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNR 396
Query: 380 PFIYFLREPNTGITVFFDRI 399
PF+ L E T +F ++
Sbjct: 397 PFLLLLWEVTTQSLLFLGKV 416
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 122 bits (305), Expect = 8e-28
Identities = 102/391 (26%), Positives = 175/391 (44%), Gaps = 29/391 (7%)
Query: 21 HLREGMTLLKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADAL 80
H+ G+ +FA LY+ + + N + SP +S L L GA +T ++ L
Sbjct: 44 HVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGL 103
Query: 81 GYTV---HDKRVKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANS 137
+ + + + + TL SS ++ + ++FV+ L F E S
Sbjct: 104 KFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGS 163
Query: 138 SLEPADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQ--LVLVSTMSFQ 195
D + A+++ G G + + +Q +VLV+ + F+
Sbjct: 164 EAFATDFQD---------SAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFK 214
Query: 196 GTWRKRFSSTDTQILPFTCAYGLVLQVPMM--HQTTEVNYGQFQDTAGHQVGVLELPYLG 253
W F DT F + + VPMM H T + Y + ++ + V+EL Y G
Sbjct: 215 AKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLT-IPYFRDEELS---CTVVELKYTG 270
Query: 254 SAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLR-RARMDVFLPRFRIQNQFNLKSI 312
+A +LF++ +DK + +E L T+ W SL R +++LP+F I +NL I
Sbjct: 271 NASALFILPDQDK---MEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDI 327
Query: 313 LNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRI 372
L G+ + F KA+L GI+G VS+ +HKA ++V EEGT+AS ATA+ + S +
Sbjct: 328 LLQLGIEEAFTS-KADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSAL 386
Query: 373 ----PIFKADRPFIYFLREPNTGITVFFDRI 399
I + +RPF+ + +T F ++
Sbjct: 387 VETRTIVRFNRPFLMIIVPTDTQNIFFMSKV 417
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 119 bits (299), Expect = 4e-27
Identities = 92/377 (24%), Positives = 167/377 (44%), Gaps = 29/377 (7%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT---VHDKR 88
EFA LY+ +A N TN SP ++ +L G + T ++ + L + + + +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 89 VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPN 148
+ + + TL ++ LF+ G L F+E V +S + +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 149 STAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQL------VLVSTMSFQGTWRKRF 202
Q ++ + T G ++ +L LV+ + F+G W + F
Sbjct: 176 EAKKQINDYVEKGTQG-------------KIVDLVKELDRDTVFALVNYIFFKGKWERPF 222
Query: 203 SSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVL 262
DT+ F ++VPMM + N + + VL + YLG+A ++F +
Sbjct: 223 EVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLP 279
Query: 263 PRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLF 322
K L H+E LT I + + R + LP+ I ++LKS+L G+T +F
Sbjct: 280 DEGK---LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVF 336
Query: 323 DPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFI 382
A+L G++ + +S+A+HKA + + E+GT+A+GA L + S P K ++PF+
Sbjct: 337 SN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFV 395
Query: 383 YFLREPNTGITVFFDRI 399
+ + E NT +F ++
Sbjct: 396 FLMIEQNTKSPLFMGKV 412
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 119 bits (299), Expect = 4e-27
Identities = 92/377 (24%), Positives = 167/377 (44%), Gaps = 29/377 (7%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT---VHDKR 88
EFA LY+ +A N TN SP ++ +L G + T ++ + L + + + +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 89 VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPN 148
+ + + TL ++ LF+ G L F+E V +S + +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 149 STAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQL------VLVSTMSFQGTWRKRF 202
Q ++ + T G ++ +L LV+ + F+G W + F
Sbjct: 176 EAKKQINDYVEKGTQG-------------KIVDLVKELDRDTVFALVNYIFFKGKWERPF 222
Query: 203 SSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVL 262
DT+ F ++VPMM + N + + VL + YLG+A ++F +
Sbjct: 223 EVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLP 279
Query: 263 PRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLF 322
K L H+E LT I + + R + LP+ I ++LKS+L G+T +F
Sbjct: 280 DEGK---LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVF 336
Query: 323 DPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFI 382
A+L G++ + +S+A+HKA + + E+GT+A+GA L + S P K ++PF+
Sbjct: 337 SN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFV 395
Query: 383 YFLREPNTGITVFFDRI 399
+ + E NT +F ++
Sbjct: 396 FLMIEQNTKSPLFMGKV 412
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 119 bits (299), Expect = 4e-27
Identities = 92/377 (24%), Positives = 167/377 (44%), Gaps = 29/377 (7%)
Query: 32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT---VHDKR 88
EFA LY+ +A N TN SP ++ +L G + T ++ + L + + + +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 89 VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPN 148
+ + + TL ++ LF+ G L F+E V +S + +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 149 STAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQL------VLVSTMSFQGTWRKRF 202
Q ++ + T G ++ +L LV+ + F+G W + F
Sbjct: 176 EAKKQINDYVEKGTQG-------------KIVDLVKELDRDTVFALVNYIFFKGKWERPF 222
Query: 203 SSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVL 262
DT+ F ++VPMM + N + + VL + YLG+A ++F +
Sbjct: 223 EVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLP 279
Query: 263 PRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLF 322
K L H+E LT I + + R + LP+ I ++LKS+L G+T +F
Sbjct: 280 DEGK---LQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVF 336
Query: 323 DPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFI 382
A+L G++ + +S+A+HKA + + E+GT+A+GA L + S P K ++PF+
Sbjct: 337 SN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFV 395
Query: 383 YFLREPNTGITVFFDRI 399
+ + E NT +F ++
Sbjct: 396 FLMIEQNTKSPLFMGKV 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,998,064
Number of Sequences: 37866
Number of extensions: 701252
Number of successful extensions: 2387
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2156
Number of HSP's gapped (non-prelim): 83
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.