Search of human proteins with 157388919

Search of human proteins with 157388919

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo
sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo sa...   931   0.0  
gi|145275187 tRNA methyltransferase 5 [Homo sapiens]                   43   5e-04
gi|151301096 trimethylguanosine synthase homolog [Homo sapiens]        36   0.081
gi|53832021 carboxypeptidase M precursor [Homo sapiens]                31   2.6  
gi|38327526 carboxypeptidase M precursor [Homo sapiens]                31   2.6  
gi|6631081 carboxypeptidase M precursor [Homo sapiens]                 31   2.6  
gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]      30   3.4  
gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]         30   3.4  
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       30   4.4  
gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]       30   4.4  
gi|7657198 dimethyladenosine transferase [Homo sapiens]                30   5.8  
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]         29   7.6  
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           29   9.9  

>gi|157388919 homolog of yeast tRNA methyltransferase 12 [Homo
           sapiens]
          Length = 448

 Score =  931 bits (2405), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALP 60
           MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALP
Sbjct: 1   MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALP 60

Query: 61  VLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGV 120
           VLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGV
Sbjct: 61  VLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGV 120

Query: 121 KWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVS 180
           KWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVS
Sbjct: 121 KWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVS 180

Query: 181 PDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVD 240
           PDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVD
Sbjct: 181 PDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVD 240

Query: 241 LYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLS 300
           LYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLS
Sbjct: 241 LYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLS 300

Query: 301 NIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHW 360
           NIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHW
Sbjct: 301 NIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHW 360

Query: 361 LYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQIL 420
           LYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQIL
Sbjct: 361 LYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQIL 420

Query: 421 HIQPVKSYAPHVDHIVLDLECCPCPSVG 448
           HIQPVKSYAPHVDHIVLDLECCPCPSVG
Sbjct: 421 HIQPVKSYAPHVDHIVLDLECCPCPSVG 448


>gi|145275187 tRNA methyltransferase 5 [Homo sapiens]
          Length = 509

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 4/143 (2%)

Query: 191 LLLGDHGWVEHV-DNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFT 249
           +L G+   +  V +N   Y+FD ++  ++    TE  R+  L   G+VL D++AG+G F 
Sbjct: 254 VLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFA 313

Query: 250 LPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILG 309
           +P  V      V A + NP +   L  N ++N V  + ++ F  + K  L       ++ 
Sbjct: 314 IP--VAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKV-FNLDGKDFLQGPVKEELMQ 370

Query: 310 LIPSSEEGWPIACQVLRQDAGGI 332
           L+  S+E  P    V+   A  I
Sbjct: 371 LLGLSKERKPSVHVVMNLPAKAI 393


>gi|151301096 trimethylguanosine synthase homolog [Homo sapiens]
          Length = 853

 Score = 35.8 bits (81), Expect = 0.081
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 236 EVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNR 295
           +V+VD + G+G  T+ F +      V A + +P  +   RNN E+ G+AD+ +   GD  
Sbjct: 692 DVVVDAFCGVGGNTIQFALTGMR--VIAIDIDPVKIALARNNAEVYGIADKIEFICGDFL 749

Query: 296 KLKLSNIADRVIL 308
            L     AD V L
Sbjct: 750 LLASFLKADVVFL 762


>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/45 (31%), Positives = 23/45 (51%)

Query: 315 EEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEH 359
           +EG     + + Q+   + H+H   +S  G+NL  L V +  KEH
Sbjct: 25  QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH 69


>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/45 (31%), Positives = 23/45 (51%)

Query: 315 EEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEH 359
           +EG     + + Q+   + H+H   +S  G+NL  L V +  KEH
Sbjct: 25  QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH 69


>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/45 (31%), Positives = 23/45 (51%)

Query: 315 EEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEH 359
           +EG     + + Q+   + H+H   +S  G+NL  L V +  KEH
Sbjct: 25  QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH 69


>gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]
          Length = 562

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 7/89 (7%)

Query: 46  QHRVEKMPDGSVALPVLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQ 105
           + R   M +G+  L + G+   ++ LQ         SP      P PVP+      SPA 
Sbjct: 356 RRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPS--APAPGPVPAAAKWAASPAS 413

Query: 106 KLCLEVSRWVEGRG-----VKWSAELEAD 129
               +   W + RG     +  +AELE D
Sbjct: 414 HASDDYEAWADFRGGGRPLLGEAAELEDD 442


>gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 492

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 7/89 (7%)

Query: 46  QHRVEKMPDGSVALPVLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQ 105
           + R   M +G+  L + G+   ++ LQ         SP      P PVP+      SPA 
Sbjct: 179 RRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPS--APAPGPVPAAAKWAASPAS 236

Query: 106 KLCLEVSRWVEGRG-----VKWSAELEAD 129
               +   W + RG     +  +AELE D
Sbjct: 237 HASDDYEAWADFRGGGRPLLGEAAELEDD 265


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 15/34 (44%), Positives = 16/34 (47%)

Query: 104  AQKLCLEVSRWVEGRGVKWSAELEADLPRSWQRH 137
            AQ    E  R    RG  WS E + D PR W RH
Sbjct: 2105 AQGRASEDRRRERERGRNWSRERDWDRPREWDRH 2138


>gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]
          Length = 892

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 5/103 (4%)

Query: 17  PVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALPVLGETLPEQHLQELRN 76
           P  +   VT  +  Q ++E+L           V +   G V   + G+  P  HL  L  
Sbjct: 486 PGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLV-LTT 544

Query: 77  RVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRG 119
           R   G    L         +R  GC  ++++  E  RWV+G+G
Sbjct: 545 RFLFG----LLSAERMRDIERHFGCMVSERVKQEALRWVQGQG 583


>gi|7657198 dimethyladenosine transferase [Homo sapiens]
          Length = 313

 Score = 29.6 bits (65), Expect = 5.8
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 236 EVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNR 295
           +V++++  G G  T+  L  A    V ACE +P  V  L   ++   VA + Q+  GD  
Sbjct: 58  DVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL 115

Query: 296 KLKL 299
           K  L
Sbjct: 116 KTDL 119


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 8/51 (15%)

Query: 37  LQRQKLFDTQHRVEKMPDGSVAL--------PVLGETLPEQHLQELRNRVA 79
           L   +L D+ ++ E++P+GSV+L        P +GET P      +R  V+
Sbjct: 357 LMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVS 407


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 360 WLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAES 398
           WL P+   +N +KNGA +        P   PE Q  AES
Sbjct: 295 WLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAES 333


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,872,397
Number of Sequences: 37866
Number of extensions: 897533
Number of successful extensions: 2078
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2070
Number of HSP's gapped (non-prelim): 13
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.