Search of human proteins with 11056044

Search of human proteins with 11056044

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11056044 pyrophosphatase 1 [Homo sapiens]
         (289 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11056044 pyrophosphatase 1 [Homo sapiens]                          617   e-177
gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Hom...   385   e-107
gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Hom...   362   e-100
gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Hom...   319   2e-87
gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Hom...   197   9e-51
gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Hom...   139   4e-33
gi|156139122 CXXC finger 6 [Homo sapiens]                              33   0.38 
gi|21361116 versican isoform 1 [Homo sapiens]                          29   4.2  
gi|21264343 scaffold attachment factor B [Homo sapiens]                29   4.2  
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]      29   4.2  
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]                29   4.2  
gi|34101268 kelch-like 8 [Homo sapiens]                                28   7.2  
gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]    28   9.4  

>gi|11056044 pyrophosphatase 1 [Homo sapiens]
          Length = 289

 Score =  617 bits (1591), Expect = e-177
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI 60
           MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI
Sbjct: 1   MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI 60

Query: 61  ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI 120
           ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI
Sbjct: 61  ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI 120

Query: 121 DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP 180
           DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP
Sbjct: 121 DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP 180

Query: 181 GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI 240
           GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI
Sbjct: 181 GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI 240

Query: 241 SCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN 289
           SCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
Sbjct: 241 SCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN 289


>gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Homo
           sapiens]
          Length = 334

 Score =  385 bits (990), Expect = e-107
 Identities = 176/283 (62%), Positives = 223/283 (78%), Gaps = 17/283 (6%)

Query: 1   MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYAD-----------------KDV 43
           M+ + TEER  P S  YR+F KN  G YISPFHDIP+  +                 +++
Sbjct: 32  MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENL 91

Query: 44  FHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWED 103
           F+M+VE+PRW+NAKMEIATK+P+NPIKQ VK GKLRYVAN+FPYKGYIWNYG +PQTWED
Sbjct: 92  FNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWED 151

Query: 104 PGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDD 163
           P   DK T C GDNDPIDVCEIGSK+ + GE+I VK+LGILA+IDEGETDWK+IAIN +D
Sbjct: 152 PHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINAND 211

Query: 164 PDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKST 223
           P+A+ ++DI+DVK+ KPGYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++IKST
Sbjct: 212 PEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKST 271

Query: 224 HDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDAL 266
           H  WKAL+ KK NG  I+C N  +S+SPF+C  + AR++V+++
Sbjct: 272 HQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESV 314


>gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Homo
           sapiens]
          Length = 316

 Score =  362 bits (928), Expect = e-100
 Identities = 166/266 (62%), Positives = 211/266 (79%), Gaps = 1/266 (0%)

Query: 1   MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI 60
           M+ + TEER  P S  YR+F KN  G YISPFHDIP+  +    + +  + +  N + EI
Sbjct: 32  MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGI-PMKKARNDEYEI 90

Query: 61  ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI 120
           ATK+P+NPIKQ VK GKLRYVAN+FPYKGYIWNYG +PQTWEDP   DK T C GDNDPI
Sbjct: 91  ATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPI 150

Query: 121 DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP 180
           DVCEIGSK+ + GE+I VK+LGILA+IDEGETDWK+IAIN +DP+A+ ++DI+DVK+ KP
Sbjct: 151 DVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKP 210

Query: 181 GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI 240
           GYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++IKSTH  WKAL+ KK NG  I
Sbjct: 211 GYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAI 270

Query: 241 SCMNTTLSESPFKCDPDAARAIVDAL 266
           +C N  +S+SPF+C  + AR++V+++
Sbjct: 271 NCTNVQISDSPFRCTQEEARSLVESV 296


>gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Homo
           sapiens]
          Length = 305

 Score =  319 bits (818), Expect = 2e-87
 Identities = 153/283 (54%), Positives = 200/283 (70%), Gaps = 46/283 (16%)

Query: 1   MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYAD-----------------KDV 43
           M+ + TEER  P S  YR+F KN  G YISPFHDIP+  +                 +++
Sbjct: 32  MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENL 91

Query: 44  FHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWED 103
           F+M+VE+PRW+NAKMEIATK+P+NPIKQ VK GKLRYVAN+FPYKGYIWNYG +PQ    
Sbjct: 92  FNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQ---- 147

Query: 104 PGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDD 163
                                    + + GE+I VK+LGILA+IDEGETDWK+IAIN +D
Sbjct: 148 -------------------------ILSCGEVIHVKILGILALIDEGETDWKLIAINAND 182

Query: 164 PDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKST 223
           P+A+ ++DI+DVK+ KPGYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++IKST
Sbjct: 183 PEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKST 242

Query: 224 HDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDAL 266
           H  WKAL+ KK NG  I+C N  +S+SPF+C  + AR++V+++
Sbjct: 243 HQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESV 285


>gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Homo
           sapiens]
          Length = 232

 Score =  197 bits (501), Expect = 9e-51
 Identities = 86/139 (61%), Positives = 118/139 (84%)

Query: 128 KVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATV 187
           ++ + GE+I VK+LGILA+IDEGETDWK+IAIN +DP+A+ ++DI+DVK+ KPGYLEAT+
Sbjct: 74  EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133

Query: 188 DWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTL 247
           +WFR YKVPDGKPEN+FAFN EFK+K FA+++IKSTH  WKAL+ KK NG  I+C N  +
Sbjct: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193

Query: 248 SESPFKCDPDAARAIVDAL 266
           S+SPF+C  + AR++V+++
Sbjct: 194 SDSPFRCTQEEARSLVESV 212



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 22/37 (59%), Positives = 26/37 (70%)

Query: 1  MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPI 37
          M+ + TEER  P S  YR+F KN  G YISPFHDIP+
Sbjct: 32 MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPL 68


>gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Homo
           sapiens]
          Length = 168

 Score =  139 bits (349), Expect = 4e-33
 Identities = 62/106 (58%), Positives = 84/106 (79%), Gaps = 3/106 (2%)

Query: 164 PDAANYN---DINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDII 220
           P + NY    +I+DVK+ KPGYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++I
Sbjct: 43  PCSQNYRLFFNIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVI 102

Query: 221 KSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDAL 266
           KSTH  WKAL+ KK NG  I+C N  +S+SPF+C  + AR++V+++
Sbjct: 103 KSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESV 148


>gi|156139122 CXXC finger 6 [Homo sapiens]
          Length = 2136

 Score = 32.7 bits (73), Expect = 0.38
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 9/59 (15%)

Query: 94  YGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGET 152
           +GAIP  WE PG +  H    G+    D+ EI   +  +GE+ G        ++D+ ET
Sbjct: 369 FGAIPHQWELPGADPVHGEALGETP--DLPEIPGAIPVQGEVFG-------TILDQQET 418


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 151  ETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATV--DWFRRYKVPDGKPENEFAFNA 208
            +TDW V+  +V   D        D+  +    LEAT+  +  R  K+ +G  + EF +  
Sbjct: 980  KTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITEGTTQEEFPWKE 1039

Query: 209  EFKDK 213
            +  +K
Sbjct: 1040 QTAEK 1044


>gi|21264343 scaffold attachment factor B [Homo sapiens]
          Length = 915

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 5/75 (6%)

Query: 144 LAMIDEGETDWKVIAINVDDPDAANYND-INDVKRLKPGYLEATVDWFRRYKVPDGKPEN 202
           ++++DE E D   +A  V+D DA N  + ++D + L  G ++   +  + + + D +  N
Sbjct: 131 ISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETIN 190

Query: 203 EFAFNAEFKDKDFAI 217
               N +    DF I
Sbjct: 191 ----NLDTSSSDFTI 201


>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
          Length = 1231

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 1/66 (1%)

Query: 116 DNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAIN-VDDPDAANYNDIND 174
           D D  D  +  +   A+      +++  L  +DE E D   +  N  DDPDAA  N   D
Sbjct: 224 DEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGD 283

Query: 175 VKRLKP 180
               +P
Sbjct: 284 PDSEEP 289


>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
          Length = 397

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 5/59 (8%)

Query: 224 HDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPC-----ESACTVP 277
           HDHW         G   S    + S+S   C  D AR +    PP C     E+A T P
Sbjct: 13  HDHWIFAQGWGWAGHWDSTSPASSSDSSGSCPCDGARGLPQPQPPSCSSRAAEAAATTP 71


>gi|34101268 kelch-like 8 [Homo sapiens]
          Length = 620

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 18/57 (31%), Positives = 25/57 (43%)

Query: 192 RYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLS 248
           R  + DG  E+ F F A    KDF   +++   +     VT K   K ISC    L+
Sbjct: 30  RSSISDGDGEDSFIFEANEAWKDFHGSLLRFYENGELCDVTLKVGSKLISCHKLVLA 86


>gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]
          Length = 745

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 8/55 (14%)

Query: 167 ANYNDINDVKRLKPGYLEATVDWFRRYK--------VPDGKPENEFAFNAEFKDK 213
           AN      V+ +K     A +DW + YK           GKP++ F F+ EF  K
Sbjct: 313 ANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAK 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,487,508
Number of Sequences: 37866
Number of extensions: 568787
Number of successful extensions: 1131
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1118
Number of HSP's gapped (non-prelim): 16
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.