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Search of human proteins with 11034825
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11034825 methionine adenosyltransferase II, beta isoform 1
[Homo sapiens]
(334 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 684 0.0
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 642 0.0
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 37 0.032
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 37 0.032
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 33 0.36
gi|66773344 hypothetical protein LOC140710 [Homo sapiens] 33 0.36
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 32 0.61
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 32 0.61
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 32 0.61
gi|4507709 tissue specific transplantation antigen P35B [Homo sa... 30 3.0
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 30 3.9
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 29 5.2
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 29 5.2
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens] 29 6.7
gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 28 8.8
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 28 8.8
gi|4757828 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 5 ... 28 8.8
>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
sapiens]
Length = 334
Score = 684 bits (1764), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF 60
MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF
Sbjct: 1 MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF 60
Query: 61 RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL 120
RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL
Sbjct: 61 RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL 120
Query: 121 AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL 180
AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL
Sbjct: 121 AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL 180
Query: 181 RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML 240
RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML
Sbjct: 181 RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML 240
Query: 241 DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL 300
DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL
Sbjct: 241 DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL 300
Query: 301 ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH 334
ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
Sbjct: 301 ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH 334
>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
sapiens]
Length = 323
Score = 642 bits (1657), Expect = 0.0
Identities = 313/314 (99%), Positives = 314/314 (100%)
Query: 21 EEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH 80
+EEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH
Sbjct: 10 QEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH 69
Query: 81 IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF 140
IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF
Sbjct: 70 IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF 129
Query: 141 DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM 200
DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM
Sbjct: 130 DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM 189
Query: 201 FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE 260
FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE
Sbjct: 190 FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE 249
Query: 261 MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW 320
MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW
Sbjct: 250 MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW 309
Query: 321 PFLIDKRWRQTVFH 334
PFLIDKRWRQTVFH
Sbjct: 310 PFLIDKRWRQTVFH 323
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 36.6 bits (83), Expect = 0.032
Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 29 RRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFEQVNLLDSNAVHHIIHD 84
+R V G +G LG+ + ++ + + GF + +F +L ++ +
Sbjct: 38 KRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKG 97
Query: 85 FQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVFDG 142
+ + HCA+ P N + ++N + N+ + + A V ++ S+ +F+G
Sbjct: 98 V--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEG 152
Query: 143 TNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 174
+ ED+P P++ Y +TK+ E+AVL N
Sbjct: 153 VDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 36.6 bits (83), Expect = 0.032
Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 29 RRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFEQVNLLDSNAVHHIIHD 84
+R V G +G LG+ + ++ + + GF + +F +L ++ +
Sbjct: 38 KRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKG 97
Query: 85 FQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVFDG 142
+ + HCA+ P N + ++N + N+ + + A V ++ S+ +F+G
Sbjct: 98 V--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEG 152
Query: 143 TNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 174
+ ED+P P++ Y +TK+ E+AVL N
Sbjct: 153 VDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 33.1 bits (74), Expect = 0.36
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 66 KFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEA- 124
KF Q ++ DS+ V + + +++H AA+ D+ + + +NV + L A
Sbjct: 71 KFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAH 130
Query: 125 -AAVGAFLIYISSDYVFDGTNPPYREEDIP-APLNLYGKTKLDGE 167
A V F IY+S+D V+ G+ +E P P N Y +K E
Sbjct: 131 EARVEKF-IYVSTDEVYGGSLDKEFDESSPKQPTNPYASSKAAAE 174
>gi|66773344 hypothetical protein LOC140710 [Homo sapiens]
Length = 1016
Score = 33.1 bits (74), Expect = 0.36
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 8/64 (12%)
Query: 4 REKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRA 63
RE EL +H +LVEEE N+ +RR++ + R + E H GCG A
Sbjct: 204 RETELKVHL-----KLVEEEANLLSRRIV---ELEVENRGLRAEMDDMKDHGGGCGGPEA 255
Query: 64 RPKF 67
R F
Sbjct: 256 RLAF 259
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.61
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 30 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 68
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 69 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 128
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 129 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 170
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.61
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 30 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 68
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 69 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 128
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 129 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 170
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.61
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 30 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 68
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 69 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 128
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 129 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 170
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|4507709 tissue specific transplantation antigen P35B [Homo
sapiens]
Length = 321
Score = 30.0 bits (66), Expect = 3.0
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 30 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKF---EQVNLLDSNAVHHIIHDFQ 86
R+LVTG +GL+G+A+ K A G G F + +L D+ + Q
Sbjct: 9 RILVTGGSGLVGKAIQKVV------ADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQ 62
Query: 87 PHVIVHCAA 95
P ++H AA
Sbjct: 63 PTHVIHLAA 71
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 29.6 bits (65), Expect = 3.9
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 156 LNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEE 194
+NL G T LD + E + AA R+ L+ E+EK E+
Sbjct: 427 MNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQ 465
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 29.3 bits (64), Expect = 5.2
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 31 VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 82
VL+TG +G G + QN H + F + P KF Q ++ + V
Sbjct: 11 VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68
Query: 83 HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 140
D + H A+ + + ++NV + N+ + + V + + + +F
Sbjct: 69 QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128
Query: 141 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 174
G +E +P PL+L Y +TK E+ VLE N
Sbjct: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 29.3 bits (64), Expect = 5.2
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 148 REEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFS 207
R+E A LN KL E+ +L+ LG+ + L E ++E SA+ + D+V
Sbjct: 1822 RQEGEAAALNTV--QKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR 1879
Query: 208 NKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKG 246
++ +++ +H V R AEK LD ++ G
Sbjct: 1880 RTLDKVE--REKLRSHEDTV----RLSAEKGRLDRTLTG 1912
>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
Length = 260
Score = 28.9 bits (63), Expect = 6.7
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 28 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGC 58
+R LVTGA+G +G AV + Q VGC
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGC 41
>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
Length = 538
Score = 28.5 bits (62), Expect = 8.8
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 16/87 (18%)
Query: 165 DGEKAVLENNLGAAVLRIPI--------LYGEVEKLEESAVTVMFDKVQFSNKSANMDHW 216
D E A++ GA + +P LY E+L+ + S K ++D+
Sbjct: 38 DSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLA--------SLKFLSLDYI 89
Query: 217 QQRFPTHVKDVATVCRQLAEKRMLDPS 243
QR +KD + ++L EKRML+ S
Sbjct: 90 PQRKQEPIKDALMLFQRLQEKRMLEES 116
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 28.5 bits (62), Expect = 8.8
Identities = 12/18 (66%), Positives = 13/18 (72%)
Query: 307 QRTPFRIGIKESLWPFLI 324
Q TPF +GI ES W FLI
Sbjct: 4046 QFTPFHLGITESSWTFLI 4063
>gi|4757828 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 5
[Homo sapiens]
Length = 388
Score = 28.5 bits (62), Expect = 8.8
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 241 DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDS--PVLGAQRPRNAQLDCS 298
DP+IK HW ++ M ++++A I F HL + P+L QR + A
Sbjct: 144 DPTIKLGGHWKPSDCMPRWKVAILI--PFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVE 201
Query: 299 KLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH 334
++ T + F +G +E+ + D W +FH
Sbjct: 202 QVGTQPFNRAMLFNVGFQEA----MKDLDWDCLIFH 233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,996,083
Number of Sequences: 37866
Number of extensions: 562632
Number of successful extensions: 1075
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1068
Number of HSP's gapped (non-prelim): 19
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.