Guide to the Human Genome
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Search of human proteins with 156071456

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156071456 serpin peptidase inhibitor, clade B, member 11
[Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   780   0.0  
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   338   4e-93
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   330   1e-90
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   327   1e-89
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   324   1e-88
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o...   324   1e-88
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   323   1e-88
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   322   4e-88
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   322   5e-88
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   312   4e-85
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   303   1e-82
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   303   1e-82
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   293   1e-79
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   291   5e-79
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   291   5e-79
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   257   1e-68
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ...   240   2e-63
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   234   8e-62
gi|170295807 neuroserpin precursor [Homo sapiens]                     219   4e-57
gi|4826904 neuroserpin precursor [Homo sapiens]                       219   4e-57
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom...   193   2e-49
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo...   193   2e-49
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo...   193   2e-49

>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  780 bits (2015), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF
Sbjct: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ
Sbjct: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
           NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL
Sbjct: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP
Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           MRAQFKANHPFLFFIRHTHTNTILFCGKLASP
Sbjct: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  338 bits (868), Expect = 4e-93
 Identities = 174/405 (42%), Positives = 266/405 (65%), Gaps = 13/405 (3%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SL TAN +FC D+F+E+  ++   NIFFS LSL  AL MV LGAR ++  Q+++VLHF
Sbjct: 1   MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60

Query: 61  SHTV--DSLKPGFKDSPKCSQAGRIHSE-------FGVEFSQINQPDSNCTLSIANRLYG 111
           +     +S +P         +AG +++E       FG   S++++  ++ TLSIANRLYG
Sbjct: 61  NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120

Query: 112 TKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTID 171
            +     Q+YL    ++Y   +++VDF+++ E++R+ IN WVE ++ GK+  LF K  I+
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180

Query: 172 PSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQM 231
             +V+VLVNA+YFK +W+  F    TV +PF L+  +N +V+MM Q G +++ F++E + 
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240

Query: 232 QVLELPYVNNKLSMIILLPV----GIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLP 287
           Q+LE+ Y   KLSM +LLP      +  L+++E+++       W+SS NM E  V +  P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300

Query: 288 RFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAA 347
           RF LE  Y+LNS+L+ +G+TD+F++ +ADL+G+SP+  LYLSK IHK++++V E GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360

Query: 348 AATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           AATG  ++ +SL    +F ANHPFLFFIRH  T TILF G++ SP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  330 bits (847), Expect = 1e-90
 Identities = 181/396 (45%), Positives = 242/396 (61%), Gaps = 21/396 (5%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  LS+AN  F LD+F  L+ NN   NIF S  S+  A++MV LG RG T  QL K  HF
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           + TV+                 +HS F    + IN+  ++  L +ANRLYG KT  F  +
Sbjct: 61  N-TVEE----------------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPE 103

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           +L  ++K Y A L +VDF+ ++E+ RKTIN WV+ +T GK+  L     +D  + +VLVN
Sbjct: 104 FLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVN 163

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKG W++KF    T  +PF+L++    TV+MMYQ   F   ++++ + +VLELPY  
Sbjct: 164 AIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQG 223

Query: 241 NKLSMIILLPVGI----ANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYE 296
            +LSM+ILLP  I      LK+IE+QL     HEWT   N+   EV V LPRFKLE  Y 
Sbjct: 224 EELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYT 283

Query: 297 LNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAV 356
           LNS L  LGV DLFN  KADLSGMS  + +++SK +HKS+++V+EEGTEAAAAT      
Sbjct: 284 LNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF 343

Query: 357 KSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
             L     F A+HPFLFFIRH  + +ILF G+ +SP
Sbjct: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  327 bits (837), Expect = 1e-89
 Identities = 169/392 (43%), Positives = 245/392 (62%), Gaps = 1/392 (0%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SL   +     D+FKEL   N G NIFFS + +L A+ MVLLG RG T  QLE+V H 
Sbjct: 1   MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
                S +   ++         +H +F    ++I++  ++  L+I NRL+G KT  F Q+
Sbjct: 60  EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           YL   EK+Y A L+ VDF  + +E+RK IN+WVE+KTN K+ +LF   +I  S+ +VLVN
Sbjct: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
            +YFKGQW  +F+   T +  F +++  + +V+MM Q  +F   F+++ Q ++L +PY N
Sbjct: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
           N LSM +LLP  I  L++I  +++     EWTS  +M ER+V +HLPRF++E  Y+L ++
Sbjct: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L ++G+ D F++ KAD SGMS   GLY  K +H S++ V+EEGTEAAAATG    V S P
Sbjct: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
                  NHPFLFFIRH  +N+ILF G+ +SP
Sbjct: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  324 bits (830), Expect = 1e-88
 Identities = 171/392 (43%), Positives = 252/392 (64%), Gaps = 12/392 (3%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SL+ AN EFC ++F+E++ N    N+FFSSLSL  AL++V LGA+ ++  Q++K+LH 
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           +        G+ +S   SQ+G + S+    FS IN    +  LSI N L+  K   FH+ 
Sbjct: 61  NTA-----SGYGNSSN-SQSG-LQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKD 113

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           Y+ C+EK Y A+++ VDF    E+TR+ IN WVEN+T+GK+ N+ G+  I  S+VMVLVN
Sbjct: 114 YIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVN 173

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           A+YFKG+WQ+ F   ET+   F+  +     V MM+Q   F L+ +++P M++LEL Y N
Sbjct: 174 AVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-N 232

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
             ++M +LLP    +L +IE +L      EWT+   M  + VEV  P+FK+E  YE+   
Sbjct: 233 GGINMYVLLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQY 290

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L++LG+ D+F++ KADLSG++    LY+S+ +HKSY++V+EEGTEA AATG +I  K LP
Sbjct: 291 LRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLP 350

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
               F+A+HPFLF IR    + ILF GK++ P
Sbjct: 351 QSTLFRADHPFLFVIR--KDDIILFSGKVSCP 380


>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  324 bits (830), Expect = 1e-88
 Identities = 171/392 (43%), Positives = 252/392 (64%), Gaps = 12/392 (3%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SL+ AN EFC ++F+E++ N    N+FFSSLSL  AL++V LGA+ ++  Q++K+LH 
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           +        G+ +S   SQ+G + S+    FS IN    +  LSI N L+  K   FH+ 
Sbjct: 61  NTA-----SGYGNSSN-SQSG-LQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKD 113

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           Y+ C+EK Y A+++ VDF    E+TR+ IN WVEN+T+GK+ N+ G+  I  S+VMVLVN
Sbjct: 114 YIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVN 173

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           A+YFKG+WQ+ F   ET+   F+  +     V MM+Q   F L+ +++P M++LEL Y N
Sbjct: 174 AVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-N 232

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
             ++M +LLP    +L +IE +L      EWT+   M  + VEV  P+FK+E  YE+   
Sbjct: 233 GGINMYVLLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQY 290

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L++LG+ D+F++ KADLSG++    LY+S+ +HKSY++V+EEGTEA AATG +I  K LP
Sbjct: 291 LRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLP 350

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
               F+A+HPFLF IR    + ILF GK++ P
Sbjct: 351 QSTLFRADHPFLFVIR--KDDIILFSGKVSCP 380


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  323 bits (829), Expect = 1e-88
 Identities = 170/393 (43%), Positives = 252/393 (64%), Gaps = 4/393 (1%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SLS AN +F  D+F++   +   +NIF+S +S+  AL MVLLGA+  T +Q+ KVLHF
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
               ++       +    ++G +H +F    ++ N+      L IAN+L+G KT  F Q+
Sbjct: 60  DQVTENTTEKAA-TYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQE 118

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           YL   +K+YQ  +++ DF  + EE+RK IN+WVE++TN K+ NLF   TI   + +VLVN
Sbjct: 119 YLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVN 178

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKGQW+NKF+   T +  F  ++    +V+MM Q  +F  A +++ Q +VLE+PY  
Sbjct: 179 AIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKG 238

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
             LSMI+LLP  I  L+++E++L +    EWTS  NM E  V++HLPRFK+E  Y+L   
Sbjct: 239 KDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDT 298

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L+++G+ ++FN   ADLSGM+ + GL +SK +HK++++V+EEG EAAAAT   +   S P
Sbjct: 299 LRTMGMVNIFNG-DADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSP 357

Query: 361 -MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
               +F  NHPFLFFIR   TN+ILF G+ +SP
Sbjct: 358 STNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  322 bits (825), Expect = 4e-88
 Identities = 169/394 (42%), Positives = 254/394 (64%), Gaps = 6/394 (1%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SLS AN +F  D+F++   +   +NIF+S +S+  AL MVLLGA+  T +Q++KVLHF
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSK-ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
               ++   G   +    ++G +H +F    ++ N+      L IAN+L+G KT  F Q+
Sbjct: 60  DQVTENTT-GKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQE 118

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           YL   +K+YQ  +++VDF  + EE+RK IN+WVE++TN K+ NL  +  I  ++ +VLVN
Sbjct: 119 YLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVN 178

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKGQW+ KF   +T +  F  ++    +++MM Q  +F  A +++ Q +VLE+PY  
Sbjct: 179 AIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKG 238

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
             LSMI+LLP  I  L+++E++L +    EWTS  NM E  V++HLPRFK+E  Y+L   
Sbjct: 239 KDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDT 298

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L+++G+ D+FN   ADLSGM+ ++GL LS  +HK++++V+EEG EAAAAT   +   S P
Sbjct: 299 LRTMGMVDIFNG-DADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATA-VVGFGSSP 356

Query: 361 --MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
                +F  NHPFLFFIR   TN+ILF G+ +SP
Sbjct: 357 TSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  322 bits (824), Expect = 5e-88
 Identities = 167/402 (41%), Positives = 256/402 (63%), Gaps = 15/402 (3%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M SL+T+  +F L++ K+L  +  G NIFFSS S+  +L++V LGA+G T  Q+ +VL F
Sbjct: 1   MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60

Query: 61  SHTVDSLKPGFKDSPKC----------SQAGRIHSEFGVEFSQINQPDSNCTLSIANRLY 110
           +        G K  P+           S +  IHS+F    S+I +P+ +  L  AN +Y
Sbjct: 61  NRD-----QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIY 115

Query: 111 GTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTI 170
           G KT AFH +YL   + ++ A  Q V+F +++++ RK IN+WVE +T GK+ NL    ++
Sbjct: 116 GEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSV 175

Query: 171 DPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ 230
           D ++ M+LVNA+YFKG W+++F V+ T + PF+++E  +  V+MM+      +  +++P+
Sbjct: 176 DSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPK 235

Query: 231 MQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFK 290
              L+L Y +  LS++ILLP  I  L+Q+EK +     +EWTS+  M   EV++HLP+FK
Sbjct: 236 AVGLQLYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFK 295

Query: 291 LETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAAT 350
           LE  Y+L S L S+G++D F+Q KAD SGMS  + L+LS   HK++++++E+GTEAAA +
Sbjct: 296 LEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGS 355

Query: 351 GDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           G  I ++      +F ANHPFLFFIRH  TNTILF G+L SP
Sbjct: 356 GSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  312 bits (799), Expect = 4e-85
 Identities = 166/392 (42%), Positives = 243/392 (61%), Gaps = 16/392 (4%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  L+ AN  F L++ K L  +N   N+FFS +S+  AL+MV +GA+G T  Q+ ++L F
Sbjct: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           +              K    G IH  F    +++N+  +   L +ANRL+G K+  F   
Sbjct: 60  N--------------KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSS 105

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           +    +K+YQA ++ +DF  + E++RK IN WV  KT GK+A L    ++DP + +VLVN
Sbjct: 106 FRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVN 165

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           A+YF+G W  +F    T +  F++S+ +   V+MM++  TFK  ++ E   Q+L LPYV 
Sbjct: 166 AVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVG 225

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
            +L+MII+LP    +L+ +EK+L    F EWT    M E EVEV LPRFKLE  Y++ S+
Sbjct: 226 KELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESV 285

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L++LG+TD F   KAD SGMS T  L LSK +HKS+++V+EEGTEAAAAT   + ++   
Sbjct: 286 LRNLGMTDAFELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCAR 344

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
              +F A+HPFLFFI+H+ TN ILFCG+ +SP
Sbjct: 345 FVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  303 bits (777), Expect = 1e-82
 Identities = 168/392 (42%), Positives = 231/392 (58%), Gaps = 18/392 (4%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  L  AN  F + +FK L   +   N+FFS +S+  AL+MV +GA+G T  Q+ + L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
                     +KD       G IH  F    S++N+  +   L  ANRL+G KT  F   
Sbjct: 61  ----------YKD-------GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           +    +K+YQA L+ + F + TEE RK IN WV  KT GK++ +    T+DP + +VLVN
Sbjct: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKG+W  +F  + T    F+ +E K  TV+MM++   FK+ +  E   QVLELPYV 
Sbjct: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMMFKEAKFKMGYADEVHTQVLELPYVE 222

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
            +LSM+ILLP    +L  +EK L    F  WT+S  + + +V+V LPR KLE  Y+L   
Sbjct: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L+ LG+ D F++ KAD SGMS  K + LSK  HK +++V+EEGTEAAAAT      +   
Sbjct: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           M  +F A+HPFLFFIRH  TN ILFCG+ +SP
Sbjct: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  303 bits (777), Expect = 1e-82
 Identities = 168/392 (42%), Positives = 231/392 (58%), Gaps = 18/392 (4%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  L  AN  F + +FK L   +   N+FFS +S+  AL+MV +GA+G T  Q+ + L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
                     +KD       G IH  F    S++N+  +   L  ANRL+G KT  F   
Sbjct: 61  ----------YKD-------GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           +    +K+YQA L+ + F + TEE RK IN WV  KT GK++ +    T+DP + +VLVN
Sbjct: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKG+W  +F  + T    F+ +E K  TV+MM++   FK+ +  E   QVLELPYV 
Sbjct: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMMFKEAKFKMGYADEVHTQVLELPYVE 222

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
            +LSM+ILLP    +L  +EK L    F  WT+S  + + +V+V LPR KLE  Y+L   
Sbjct: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
           L+ LG+ D F++ KAD SGMS  K + LSK  HK +++V+EEGTEAAAAT      +   
Sbjct: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342

Query: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           M  +F A+HPFLFFIRH  TN ILFCG+ +SP
Sbjct: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  293 bits (751), Expect = 1e-79
 Identities = 163/393 (41%), Positives = 231/393 (58%), Gaps = 18/393 (4%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M +LS A+  F + + K L  +N   N+F S +S+  AL+MVLLGA+G T  Q+ + L  
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
           +   D                 IH  F    +++N+  +   L  ANRL+G KT  F   
Sbjct: 61  NTEED-----------------IHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLST 103

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           +     ++Y A L+ + F ++ EE+RK IN WV  KT GK+  L   S+ID  + +VLVN
Sbjct: 104 FKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVN 163

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           AIYFKG+W   F    T + PF++++ +   V+MMYQ  TFKLA V E + Q+LELPY  
Sbjct: 164 AIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYAR 223

Query: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
            +LS+++LLP     L  +EK L       WT    M   EVEV LP+FKL+  Y++ S+
Sbjct: 224 KELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESV 283

Query: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVK-SL 359
           L+ LG+ D F Q KADLS MS  + L LSK +HKS+++V+EEGTEAAAA+   +  +  +
Sbjct: 284 LRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCM 343

Query: 360 PMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
               +F A+HPFLFFIRH   N+ILFCG+ +SP
Sbjct: 344 ESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  291 bits (746), Expect = 5e-79
 Identities = 161/416 (38%), Positives = 247/416 (59%), Gaps = 25/416 (6%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  L  AN  F L++FK L   +   N+F S  S+   ++MV +G+RG TE+Q+ KVL F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  S----HTVDSLKP---------------GFKDSPKCSQAG-RIHSEFGVEFSQINQPDSN 100
           +    + V  + P                + D+   +QA  +IHS F    S IN    N
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 101 CTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGK 160
             L   N+L+G K+ +F ++Y+   +K+Y +  Q VDF +  EE RK IN+WV+ +T GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 161 VANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGT 220
           + NL  + ++D  + MVLVNA+YFKG+W+  F+ +     PF+++  +   V+MMY    
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 221 FKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIAN----LKQIEKQLNSGTFHEWTSSSN 276
             + ++++ + Q+LELPY  + +SM +LLP  IA+    L+ +E ++     ++WTS   
Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 277 MMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSY 336
           M E EVEV++P+FKLE  YEL S+L+S+G+ D FN+ +A+ SGMS    L+LS+  H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 337 LDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           +DV+EEGTEAAA TG  +  ++     QF A+HPFLF I H  TN ILF G+ +SP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  291 bits (746), Expect = 5e-79
 Identities = 161/416 (38%), Positives = 247/416 (59%), Gaps = 25/416 (6%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M  L  AN  F L++FK L   +   N+F S  S+   ++MV +G+RG TE+Q+ KVL F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  S----HTVDSLKP---------------GFKDSPKCSQAG-RIHSEFGVEFSQINQPDSN 100
           +    + V  + P                + D+   +QA  +IHS F    S IN    N
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 101 CTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGK 160
             L   N+L+G K+ +F ++Y+   +K+Y +  Q VDF +  EE RK IN+WV+ +T GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 161 VANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGT 220
           + NL  + ++D  + MVLVNA+YFKG+W+  F+ +     PF+++  +   V+MMY    
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 221 FKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIAN----LKQIEKQLNSGTFHEWTSSSN 276
             + ++++ + Q+LELPY  + +SM +LLP  IA+    L+ +E ++     ++WTS   
Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 277 MMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSY 336
           M E EVEV++P+FKLE  YEL S+L+S+G+ D FN+ +A+ SGMS    L+LS+  H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 337 LDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
           +DV+EEGTEAAA TG  +  ++     QF A+HPFLF I H  TN ILF G+ +SP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  257 bits (657), Expect = 1e-68
 Identities = 152/394 (38%), Positives = 229/394 (58%), Gaps = 20/394 (5%)

Query: 4   LSTANVEFCLDVFKEL-NSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSH 62
           LS AN  F    ++ L +S N  DNIF S LS+  A +M  LGA  +T +QL +V  F  
Sbjct: 83  LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKF-- 140

Query: 63  TVDSLKPGFKDSPKCSQAGRIHSEFG-VEFSQINQPDSNCTLSIANRLYGTKTMAFHQQY 121
                     D+     + +IH  F  +      + + +  L  ANRL+G K++ F++ Y
Sbjct: 141 ----------DTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETY 190

Query: 122 LSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNA 181
              SE  Y A+LQ +DF+++ E++R  IN WV NKT G++ ++     I+  +V+VLVN 
Sbjct: 191 QDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNT 250

Query: 182 IYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNN 241
           IYFKG W++KF    T K  F  ++G++ +  MMYQ G F+   V E   QVLELP+  +
Sbjct: 251 IYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGD 309

Query: 242 KLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLL 301
            ++M+++LP    +L ++EK+L      EW     + E  + VH+PRF++E  + L   L
Sbjct: 310 DITMVLILPKPEKSLAKVEKELTPEVLQEWL--DELEEMMLVVHMPRFRIEDGFSLKEQL 367

Query: 302 KSLGVTDLFNQVKADLSGM--SPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSL 359
           + +G+ DLF+  K+ L G+       LY+S A HK++L+V+EEG+EAAA+T   IA +SL
Sbjct: 368 QDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSL 427

Query: 360 -PMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
            P R  FKAN PFL FIR    NTI+F G++A+P
Sbjct: 428 NPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 461


>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 5 [Homo sapiens]
          Length = 375

 Score =  240 bits (612), Expect = 2e-63
 Identities = 134/399 (33%), Positives = 224/399 (56%), Gaps = 31/399 (7%)

Query: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
           M +L  AN  F +D+FK+L       N+ FS + L  +LS+  +GA+G+T  ++ +VLHF
Sbjct: 1   MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60

Query: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
            +  D                 +   F    S +N+  S  +L +  RLY  K++    +
Sbjct: 61  ENVKD-----------------VPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTE 103

Query: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
           ++S +++ Y   L+TVDF+   EET+  IN  +++ T+G   N+   ++++  + +++VN
Sbjct: 104 FISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVN 163

Query: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
           A YF G+W  KF   ET + PF++++     V+MM    TF +  +     +++ELP+ N
Sbjct: 164 AAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQN 223

Query: 241 NKLSMIILLPVGI----ANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYE 296
             LSM ILLP  +      L++IEKQLNS +  +WT+ S M   +V++ +P+FK+E   +
Sbjct: 224 KHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMID 283

Query: 297 LNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAV 356
             + L++LG+  +F++  +D SGMS TKG+ LS  IHK  L+++E+G       GDSI V
Sbjct: 284 PKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDG-------GDSIEV 336

Query: 357 ---KSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
              + L  + +  A+HPF++ IRH  T  I+F GK  SP
Sbjct: 337 PGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  234 bits (598), Expect = 8e-62
 Identities = 134/387 (34%), Positives = 220/387 (56%), Gaps = 22/387 (5%)

Query: 8   NVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSL 67
           N EF +D+++E++ ++  DNI FS L +   L MV LGA+G+ ++Q+ + L    T    
Sbjct: 26  NTEFAVDLYQEVSLSH-KDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQET---- 80

Query: 68  KPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEK 127
                       AG         FS I++     T ++AN LY  +     +QYL  +++
Sbjct: 81  -----------SAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKE 129

Query: 128 WYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQ 187
           ++Q+ ++ VDF Q  +   + I+ WVE KT+GK+ ++F      P + +VLVNAIYFKG 
Sbjct: 130 FFQSAIKLVDF-QDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGD 188

Query: 188 WQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQM--QVLELPYVNNKLSM 245
           W+ KF+  +T    F    G  V + MM  +   K  +  E  +  QVLEL Y  ++ S+
Sbjct: 189 WKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSL 248

Query: 246 IILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLG 305
           II+LP    +++++EK + +    +W S   M E EVE+ LPRFK+E K +   +L SL 
Sbjct: 249 IIILPAEGMDIEEVEKLITAQQILKWLSE--MQEEEVEISLPRFKVEQKVDFKDVLYSLN 306

Query: 306 VTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQF 365
           +T++F+    DLSG++ +  +Y+S+   K + +++E+G+EAA +TG  I V     ++QF
Sbjct: 307 ITEIFSG-GCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQF 365

Query: 366 KANHPFLFFIRHTHTNTILFCGKLASP 392
            ANHPFLF ++H  T +ILF G++ +P
Sbjct: 366 IANHPFLFIMKHNPTESILFMGRVTNP 392


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  219 bits (557), Expect = 4e-57
 Identities = 132/393 (33%), Positives = 217/393 (55%), Gaps = 27/393 (6%)

Query: 7   ANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDS 66
           A  +  ++++  L +    +NI FS LS+  A+ M+ LGA+G T++++   + +    DS
Sbjct: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGY----DS 80

Query: 67  LKPGFKDSPKCSQAGRIHSEFGVEFSQ-INQPDSNCTLSIANRLYGTKTMAFHQQYLSCS 125
           LK G + S            F  EFS  +   +S   + IAN L+       ++++L   
Sbjct: 81  LKNGEEFS------------FLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMM 128

Query: 126 EKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFK 185
           +K++ A +  VDF Q+       IN WVEN TN  V +L      D ++ + L+NA+YFK
Sbjct: 129 KKYFNAAVNHVDFSQNVA-VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFK 187

Query: 186 GQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ------MQVLELPYV 239
           G W+++F+   T    F   +   V + MMYQ G F      +         QVLE+PY 
Sbjct: 188 GNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYE 247

Query: 240 NNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNS 299
            +++SM+++L      L  +E  + +    EW +S  + +++VEV+LPRF +E + +L  
Sbjct: 248 GDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANS--VKKQKVEVYLPRFTVEQEIDLKD 305

Query: 300 LLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSL 359
           +LK+LG+T++F +  A+L+G+S  K ++LSKAIHKS+L+V+EEG+EAAA +G     +  
Sbjct: 306 VLKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMA 364

Query: 360 PMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
            +  Q   +HPF F IR+  T TILF G++  P
Sbjct: 365 VLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  219 bits (557), Expect = 4e-57
 Identities = 132/393 (33%), Positives = 217/393 (55%), Gaps = 27/393 (6%)

Query: 7   ANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDS 66
           A  +  ++++  L +    +NI FS LS+  A+ M+ LGA+G T++++   + +    DS
Sbjct: 25  AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGY----DS 80

Query: 67  LKPGFKDSPKCSQAGRIHSEFGVEFSQ-INQPDSNCTLSIANRLYGTKTMAFHQQYLSCS 125
           LK G + S            F  EFS  +   +S   + IAN L+       ++++L   
Sbjct: 81  LKNGEEFS------------FLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMM 128

Query: 126 EKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFK 185
           +K++ A +  VDF Q+       IN WVEN TN  V +L      D ++ + L+NA+YFK
Sbjct: 129 KKYFNAAVNHVDFSQNVA-VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFK 187

Query: 186 GQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ------MQVLELPYV 239
           G W+++F+   T    F   +   V + MMYQ G F      +         QVLE+PY 
Sbjct: 188 GNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYE 247

Query: 240 NNKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNS 299
            +++SM+++L      L  +E  + +    EW +S  + +++VEV+LPRF +E + +L  
Sbjct: 248 GDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANS--VKKQKVEVYLPRFTVEQEIDLKD 305

Query: 300 LLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSL 359
           +LK+LG+T++F +  A+L+G+S  K ++LSKAIHKS+L+V+EEG+EAAA +G     +  
Sbjct: 306 VLKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMA 364

Query: 360 PMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
            +  Q   +HPF F IR+  T TILF G++  P
Sbjct: 365 VLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  193 bits (491), Expect = 2e-49
 Identities = 122/383 (31%), Positives = 206/383 (53%), Gaps = 23/383 (6%)

Query: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69
           EF   ++++L   +   NIFFS +S+  A +M+ LG + +T +++ + L+F+ T      
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------ 109

Query: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129
              + P+     +IH  F      +NQPDS   L+  N L+ ++ +    ++L   +K Y
Sbjct: 110 ---EIPEA----QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLY 162

Query: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189
            +   TV+F   TEE +K IN +VE  T GK+ +L  +  +D  +V  LVN I+FKG+W+
Sbjct: 163 HSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWE 219

Query: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILL 249
             F+V++T +  F + +   V V MM ++G F +   K+    VL + Y+ N  ++  L 
Sbjct: 220 RPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLP 279

Query: 250 PVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDL 309
             G   L+ +E +L      ++  + +   R   +HLP+  +   Y+L S+L  LG+T +
Sbjct: 280 DEG--KLQHLENELTHDIITKFLENED--RRSASLHLPKLSITGTYDLKSVLGQLGITKV 335

Query: 310 FNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKANH 369
           F+   ADLSG++    L LSKA+HK+ L + E+GTEAA A        S+P   +F  N 
Sbjct: 336 FSN-GADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NK 392

Query: 370 PFLFFIRHTHTNTILFCGKLASP 392
           PF+F +   +T + LF GK+ +P
Sbjct: 393 PFVFLMIEQNTKSPLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,974,841
Number of Sequences: 37866
Number of extensions: 508469
Number of successful extensions: 1560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1268
Number of HSP's gapped (non-prelim): 68
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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