BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|15277321 RAS-like, family 10, member B [Homo sapiens] (203 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|15277321 RAS-like, family 10, member B [Homo sapiens] 421 e-118 gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens] 197 5e-51 gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens] 100 6e-22 gi|21703367 Di-Ras2 [Homo sapiens] 90 1e-18 gi|5032041 Ras homolog enriched in brain [Homo sapiens] 80 1e-15 gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 79 3e-15 gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 78 5e-15 gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 77 1e-14 gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 77 1e-14 gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 76 2e-14 gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 76 2e-14 gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 75 3e-14 gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 74 9e-14 gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 74 9e-14 gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] 73 1e-13 gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 71 6e-13 gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 71 7e-13 gi|22027486 RASD family, member 2 [Homo sapiens] 69 2e-12 gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 69 4e-12 gi|192807327 Ras-related associated with diabetes [Homo sapiens] 68 5e-12 gi|4759054 Ras-related associated with diabetes [Homo sapiens] 68 5e-12 gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 68 6e-12 gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 67 8e-12 gi|45592963 RAS-like, family 11, member A [Homo sapiens] 65 3e-11 gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 64 1e-10 gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 63 2e-10 gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 62 3e-10 gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 62 4e-10 gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 62 4e-10 gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 60 1e-09 >gi|15277321 RAS-like, family 10, member B [Homo sapiens] Length = 203 Score = 421 bits (1082), Expect = e-118 Identities = 203/203 (100%), Positives = 203/203 (100%) Query: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF Sbjct: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60 Query: 61 PPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSE 120 PPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSE Sbjct: 61 PPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSE 120 Query: 121 TPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA 180 TPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA Sbjct: 121 TPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA 180 Query: 181 RCKHVHAALRFQGALRRNRCAIM 203 RCKHVHAALRFQGALRRNRCAIM Sbjct: 181 RCKHVHAALRFQGALRRNRCAIM 203 >gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens] Length = 203 Score = 197 bits (501), Expect = 5e-51 Identities = 105/204 (51%), Positives = 134/204 (65%), Gaps = 2/204 (0%) Query: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60 M + RVAVLGA GVGK+AI+RQFL+ ++ E PT RLY PAV+++G V+DL I D Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60 Query: 61 PPIS-AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTS 119 +EW D L+ A++LVYDIC DSF+YVK +RQ+I ETR G Sbjct: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120 Query: 120 ETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGC 179 E PI++VGNKRD QR R PR ++ LVR+ W+CGY+ECSAKYNWH+L LF ELL+ Sbjct: 121 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR-CAL 179 Query: 180 ARCKHVHAALRFQGALRRNRCAIM 203 R + H ALR QGAL RC++M Sbjct: 180 VRARPAHPALRLQGALHPARCSLM 203 >gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens] Length = 115 Score = 100 bits (250), Expect = 6e-22 Identities = 56/115 (48%), Positives = 73/115 (63%), Gaps = 1/115 (0%) Query: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60 M + RVAVLGA GVGK+AI+RQFL+ ++ E PT RLY PAV+++G V+DL I D Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60 Query: 61 PPIS-AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETR 114 +EW D L+ A++LVYDIC DSF+YVK +RQ+I ETR Sbjct: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETR 115 >gi|21703367 Di-Ras2 [Homo sapiens] Length = 199 Score = 90.1 bits (222), Expect = 1e-18 Identities = 66/171 (38%), Positives = 89/171 (52%), Gaps = 13/171 (7%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 YRVAV GA GVGKS++V +F+ F E +P T Y + + + LQI D Sbjct: 8 YRVAVFGAGGVGKSSLVLRFVKGTFRESYIP-TVEDTYRQVISCDKSICTLQITDTTGSH 66 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET-PI 123 FP +Q + + HA+ILVY I S E +K I +QI E + G E+ PI Sbjct: 67 QFP--AMQRLS------ISKGHAFILVYSITSRQSLEELKPIYEQICEIK--GDVESIPI 116 Query: 124 IIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELL 174 ++VGNK D R + L R TWKC ++E SAK N ++ LF ELL Sbjct: 117 MLVGNKCDESPSREVQSSEAEALAR-TWKCAFMETSAKLNHNVKELFQELL 166 >gi|5032041 Ras homolog enriched in brain [Homo sapiens] Length = 184 Score = 80.1 bits (196), Expect = 1e-15 Identities = 49/169 (28%), Positives = 88/169 (52%), Gaps = 12/169 (7%) Query: 6 RVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISA 65 ++A+LG R VGKS++ QF+ +F + P T + + +NG + LQ++D Sbjct: 8 KIAILGYRSVGKSSLTIQFVEGQFVDSYDP-TIENTFTKLITVNGQEYHLQLVDTAGQDE 66 Query: 66 FPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIII 125 + + D ++ YILVY + SFE +K I ++L+ ++G + PI++ Sbjct: 67 YSIFPQTYSID--------INGYILVYSVTSIKSFEVIKVIHGKLLD--MVGKVQIPIML 116 Query: 126 VGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELL 174 VGNK+DL RVI + + ++W ++E SAK N + +F ++ Sbjct: 117 VGNKKDLHMERVI-SYEEGKALAESWNAAFLESSAKENQTAVDVFRRII 164 >gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] Length = 198 Score = 79.0 bits (193), Expect = 3e-15 Identities = 56/170 (32%), Positives = 87/170 (51%), Gaps = 12/170 (7%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 YRV V GA GVGKS++V +F+ F + +P T Y + + V LQI D Sbjct: 8 YRVVVFGAGGVGKSSLVLRFVKGTFRDTYIP-TIEDTYRQVISCDKSVCTLQITDTTGSH 66 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 FP +Q + + HA+ILV+ + S E + I + I++ + + P++ Sbjct: 67 QFP--AMQRLS------ISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKG-SVEDIPVM 117 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELL 174 +VGNK D + V R + V + WKC ++E SAK N+++ LF ELL Sbjct: 118 LVGNKCDETQREVDTR--EAQAVAQEWKCAFMETSAKMNYNVKELFQELL 165 >gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo sapiens] Length = 206 Score = 78.2 bits (191), Expect = 5e-15 Identities = 54/176 (30%), Positives = 91/176 (51%), Gaps = 11/176 (6%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ ++V ++G+ GVGKSA+ QF+Y+EF E PT A Y VV++G + ILD Sbjct: 12 LALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADS-YRKKVVLDGEEVQIDILD-- 68 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +++A RS ++LV+ I +SF R+QIL + + Sbjct: 69 ------TAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKA-EEDKI 121 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 P+++VGNK DL+ R +P + + W YVE SAK ++ +F +L++ + Sbjct: 122 PLLVVGNKSDLEERRQVP-VEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREI 176 >gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 76.6 bits (187), Expect = 1e-14 Identities = 57/175 (32%), Positives = 90/175 (51%), Gaps = 15/175 (8%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y++ VLG+ GVGKSA+ QF+ F E PT Y V ++ L+ILD Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDAQQCMLEILDTAGTE 62 Query: 65 AFPVNTLQEWADTCCRGL--RSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 F T R L ++ + LVY I +F ++ +R+QIL RV T + P Sbjct: 63 QF----------TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTDDVP 110 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +I+VGNK DL+ RV+ + +L R+ C ++E SAK ++ +F +L++ + Sbjct: 111 MILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQI 165 >gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 76.6 bits (187), Expect = 1e-14 Identities = 57/175 (32%), Positives = 90/175 (51%), Gaps = 15/175 (8%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y++ VLG+ GVGKSA+ QF+ F E PT Y V ++ L+ILD Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDAQQCMLEILDTAGTE 62 Query: 65 AFPVNTLQEWADTCCRGL--RSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 F T R L ++ + LVY I +F ++ +R+QIL RV T + P Sbjct: 63 QF----------TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTDDVP 110 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +I+VGNK DL+ RV+ + +L R+ C ++E SAK ++ +F +L++ + Sbjct: 111 MILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQI 165 >gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 76.3 bits (186), Expect = 2e-14 Identities = 57/175 (32%), Positives = 90/175 (51%), Gaps = 15/175 (8%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y++ VLG+ GVGKSA+ QF+ F E PT Y V ++ L+ILD Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDCQQCMLEILDTAGTE 62 Query: 65 AFPVNTLQEWADTCCRGL--RSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 F T R L ++ + LVY I +F ++ +R+QIL RV T + P Sbjct: 63 QF----------TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDVP 110 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +I+VGNK DL+ RV+ + +L R+ C ++E SAK ++ +F +L++ + Sbjct: 111 MILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQI 165 >gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] Length = 184 Score = 76.3 bits (186), Expect = 2e-14 Identities = 57/175 (32%), Positives = 90/175 (51%), Gaps = 15/175 (8%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y++ VLG+ GVGKSA+ QF+ F E PT Y V ++ L+ILD Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDCQQCMLEILDTAGTE 62 Query: 65 AFPVNTLQEWADTCCRGL--RSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 F T R L ++ + LVY I +F ++ +R+QIL RV T + P Sbjct: 63 QF----------TAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDVP 110 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +I+VGNK DL+ RV+ + +L R+ C ++E SAK ++ +F +L++ + Sbjct: 111 MILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQI 165 >gi|33946329 ras related v-ral simian leukemia viral oncogene homolog A [Homo sapiens] Length = 206 Score = 75.5 bits (184), Expect = 3e-14 Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 12/176 (6%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ ++V ++G+ GVGKSA+ QF+Y+EF E PT A Y VV++G + ILD Sbjct: 12 LALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADS-YRKKVVLDGEEVQIDILD-- 68 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +++A RS ++ V+ I +SF R+QIL RV Sbjct: 69 ------TAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQIL--RVKEDENV 120 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 P ++VGNK DL+ R + + + W YVE SAK ++ +F +L++ + Sbjct: 121 PFLLVGNKSDLEDKRQVSVEEAKNRAEQ-WNVNYVETSAKTRANVDKVFFDLMREI 175 >gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 73.9 bits (180), Expect = 9e-14 Identities = 54/176 (30%), Positives = 89/176 (50%), Gaps = 12/176 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y+V VLG+ GVGKSA+ QF+ F E P T Y + ++ L+ILD Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGSFIEKYDP-TIEDFYRKEIEVDSSPSVLEILD----- 57 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 +++A +++ +ILVY + SF+ +K +R QI+ RV P+I Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII--RVKRYERVPMI 112 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA 180 +VGNK DL+ R + + + + W C ++E SAK + LF+E+++ + A Sbjct: 113 LVGNKVDLEGEREV-SYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYA 167 >gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 73.9 bits (180), Expect = 9e-14 Identities = 54/176 (30%), Positives = 90/176 (51%), Gaps = 12/176 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y+V VLG+ GVGKSA+ QF+ F E P T Y + ++ L+ILD Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDP-TIEDFYRKEIEVDSSPSVLEILD----- 57 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 +++A +++ +ILVY + SF+ +K +R QI+ RV + P+I Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQII--RVKRYEKVPVI 112 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA 180 +VGNK DL+ R + + + + W C ++E SAK + LF+E+++ + A Sbjct: 113 LVGNKVDLESEREVSS-SEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYA 167 >gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] Length = 281 Score = 73.2 bits (178), Expect = 1e-13 Identities = 58/179 (32%), Positives = 86/179 (48%), Gaps = 22/179 (12%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTA---RRLYLPAVVMNGHVHDLQILDFP 61 YR+ +LG+ VGK+AIV +FL F + PT R+ Y + G V+ L ILD Sbjct: 25 YRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFY----SIRGEVYQLDILDTS 80 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 FP + + +ILV+ + DSFE V+ +RQQIL+T+ ++T Sbjct: 81 GNHPFPAMRR--------LSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKT 132 Query: 122 ------PIIIVGNKRDLQRGRVIPRWNVSHLV-RKTWKCGYVECSAKYNWHILLLFSEL 173 P++I GNK D R + + + LV +C Y E SAK N + +F L Sbjct: 133 KENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRAL 191 >gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] Length = 183 Score = 71.2 bits (173), Expect = 6e-13 Identities = 53/173 (30%), Positives = 89/173 (51%), Gaps = 12/173 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y+V VLG+ GVGKSA+ QF+ F E P T Y + ++ L+ILD Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDP-TIEDFYRKEIEVDSSPSVLEILD----- 57 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 +++A +++ +ILVY + SF+ +K +R QI+ RV + P+I Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIV--RVKRYEKVPLI 112 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +VGNK DL+ R + + + + W C ++E SAK + LF+E+++ + Sbjct: 113 LVGNKVDLEPEREVMS-SEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164 >gi|5902050 Ras-like without CAAX 1 [Homo sapiens] Length = 219 Score = 70.9 bits (172), Expect = 7e-13 Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 12/173 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y++ +LGA GVGKSA+ QF+ + F E P T Y + ++ +L ILD + Sbjct: 22 YKLVMLGAGGVGKSAMTMQFISHRFPEDHDP-TIEDAYKIRIRIDDEPANLDILDTAGQA 80 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 F Q +R+ +I+ Y I SF V+ +Q I RV T +TP++ Sbjct: 81 EFTAMRDQY--------MRAGEGFIICYSITDRRSFHEVREFKQLIY--RVRRTDDTPVV 130 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +VGNK DL++ R + + L R+ + C + E SA Y ++I +F L++ + Sbjct: 131 LVGNKSDLKQLRQVTKEEGLALARE-FSCPFFETSAAYRYYIDDVFHALVREI 182 >gi|22027486 RASD family, member 2 [Homo sapiens] Length = 266 Score = 69.3 bits (168), Expect = 2e-12 Identities = 56/178 (31%), Positives = 86/178 (48%), Gaps = 22/178 (12%) Query: 3 STYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTA---RRLYLPAVVMNGHVHDLQILD 59 ++YR+ VLGA VGKS+IV +FL F + PT R++Y + G ++ L ILD Sbjct: 18 NSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY----NIRGDMYQLDILD 73 Query: 60 FPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILE------T 113 FP + + +ILV+ + +SF+ VK +++QILE Sbjct: 74 TSGNHPFPAMRR--------LSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKN 125 Query: 114 RVIGTSETPIIIVGNKRDL-QRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLF 170 + +E P++I GNK D + R +P LV C Y E SAK N ++ +F Sbjct: 126 KTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 183 >gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] Length = 189 Score = 68.6 bits (166), Expect = 4e-12 Identities = 57/202 (28%), Positives = 97/202 (48%), Gaps = 13/202 (6%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ Y++ V+GA GVGKSA+ Q + N F + P T Y VV++G L ILD Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDP-TIEDSYRKQVVIDGETCLLDILD-- 57 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +E++ + +R+ ++ V+ I SFE + R+QI RV + + Sbjct: 58 ------TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQI--KRVKDSEDV 109 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCAR 181 P+++VGNK DL R + L R ++ ++E SAK + F L++ + R Sbjct: 110 PMVLVGNKCDLP-SRTVDTKQAQDLAR-SYGIPFIETSAKTRQRVEDAFYTLVREIRQYR 167 Query: 182 CKHVHAALRFQGALRRNRCAIM 203 K + + G ++ +C IM Sbjct: 168 LKKISKEEKTPGCVKIKKCIIM 189 >gi|192807327 Ras-related associated with diabetes [Homo sapiens] Length = 308 Score = 68.2 bits (165), Expect = 5e-12 Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 13/195 (6%) Query: 3 STYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPP 62 S Y+V +LGA GVGKSA+ R ++ + A Y ++V++G L + D Sbjct: 90 SVYKVLLLGAPGVGKSALAR--IFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWE 147 Query: 63 ISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 W C + AY++VY + SFE +R Q+ R T + P Sbjct: 148 QDG------GRWLPGHCMAMGD--AYVIVYSVTDKGSFEKASELRVQLRRAR--QTDDVP 197 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARC 182 II+VGNK DL R R + + + C ++E SA + ++ LF +++ + R Sbjct: 198 IILVGNKSDLVRSREV-SVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRD 256 Query: 183 KHVHAALRFQGALRR 197 A R G RR Sbjct: 257 SKEANARRQAGTRRR 271 >gi|4759054 Ras-related associated with diabetes [Homo sapiens] Length = 308 Score = 68.2 bits (165), Expect = 5e-12 Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 13/195 (6%) Query: 3 STYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPP 62 S Y+V +LGA GVGKSA+ R ++ + A Y ++V++G L + D Sbjct: 90 SVYKVLLLGAPGVGKSALAR--IFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWE 147 Query: 63 ISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETP 122 W C + AY++VY + SFE +R Q+ R T + P Sbjct: 148 QDG------GRWLPGHCMAMGD--AYVIVYSVTDKGSFEKASELRVQLRRAR--QTDDVP 197 Query: 123 IIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARC 182 II+VGNK DL R R + + + C ++E SA + ++ LF +++ + R Sbjct: 198 IILVGNKSDLVRSREV-SVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRD 256 Query: 183 KHVHAALRFQGALRR 197 A R G RR Sbjct: 257 SKEANARRQAGTRRR 271 >gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] Length = 183 Score = 67.8 bits (164), Expect = 6e-12 Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 12/177 (6%) Query: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60 +V +V +LG R VGK+++ QF+ EFSE P T Y V + L ++D Sbjct: 3 LVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDP-TVENTYSKIVTLGKDEFHLHLVD- 60 Query: 61 PPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSE 120 E++ + VH Y+LVY + SF+ ++++ Q++ E G + Sbjct: 61 -------TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGH--GKTR 111 Query: 121 TPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 P+++VGNK DL R + L ++W ++E SA+ N +F+++++ + Sbjct: 112 VPVVLVGNKADLSPEREVQAVEGKKLA-ESWGATFMESSARENQLTQGIFTKVIQEI 167 >gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a [Homo sapiens] Length = 204 Score = 67.4 bits (163), Expect = 8e-12 Identities = 54/173 (31%), Positives = 85/173 (49%), Gaps = 12/173 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 YR+ V+G GVGKSA+ QF+ + F P T Y V++ L ILD Sbjct: 15 YRLVVVGGGGVGKSALTIQFIQSYFVTDYDP-TIEDSYTKQCVIDDRAARLDILDTAGQE 73 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 F ++E + +R+ ++LV+ + SFE + ++QIL RV E P+I Sbjct: 74 EF--GAMRE------QYMRTGEGFLLVFSVTDRGSFEEIYKFQRQIL--RVKDRDEFPMI 123 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 ++GNK DL R + + L R+ K Y+E SAK ++ F EL++ + Sbjct: 124 LIGNKADLDHQRQVTQEEGQQLARQL-KVTYMEASAKIRMNVDQAFHELVRVI 175 >gi|45592963 RAS-like, family 11, member A [Homo sapiens] Length = 242 Score = 65.5 bits (158), Expect = 3e-11 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 6/173 (3%) Query: 6 RVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISA 65 ++AVLGA VGKSA++ +FL F P T +LY V + G LQI D P Sbjct: 29 KLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTG-KLYSRLVYVEGDQLSLQIQDTPG-GV 86 Query: 66 FPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIII 125 ++L + D+ + ++ ++LVY I +DS+ ++ + Q I +V S+ P+II Sbjct: 87 QIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHI--RKVHPDSKAPVII 144 Query: 126 VGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWH-ILLLFSELLKSV 177 VGNK DL R + + L + ++E S N+ + +F L K V Sbjct: 145 VGNKGDLLHARQVQTQDGIQLANELGSL-FLEISTSENYEDVCDVFQHLCKEV 196 >gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapiens] Length = 218 Score = 63.5 bits (153), Expect = 1e-10 Identities = 54/174 (31%), Positives = 82/174 (47%), Gaps = 12/174 (6%) Query: 4 TYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPI 63 T+++ V+G GVGKSA+ QF+ + F PT Y ++G L ILD Sbjct: 29 THKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDS-YTKICSVDGIPARLDILDTAGQ 87 Query: 64 SAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPI 123 F Q +R+ H ++LV+ I SF V + QIL RV + P+ Sbjct: 88 EEFGAMREQY--------MRAGHGFLLVFAINDRQSFNEVGKLFTQIL--RVKDRDDFPV 137 Query: 124 IIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 ++VGNK DL+ R +PR S + Y E SAK ++ F +L+++V Sbjct: 138 VLVGNKADLESQRQVPRSEAS-AFGASHHVAYFEASAKLRLNVDEAFEQLVRAV 190 >gi|4506533 Ras-like without CAAX 2 [Homo sapiens] Length = 217 Score = 62.8 bits (151), Expect = 2e-10 Identities = 50/173 (28%), Positives = 82/173 (47%), Gaps = 12/173 (6%) Query: 5 YRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPIS 64 Y+V +LGA GVGKSA+ QF+ ++F + P T Y V ++ L ILD + Sbjct: 21 YKVVMLGAGGVGKSAMTMQFISHQFPDYHDP-TIEDAYKTQVRIDNEPAYLDILDTAGQA 79 Query: 65 AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPII 124 F Q +R +I+ Y + SF+ ++ I + R T E P++ Sbjct: 80 EFTAMREQY--------MRGGEGFIICYSVTDRQSFQEAAKFKELIFQVR--HTYEIPLV 129 Query: 125 IVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV 177 +VGNK DL++ R + L ++ + CG+ E SA + I F L++ + Sbjct: 130 LVGNKIDLEQFRQVSTEEGLSLAQE-YNCGFFETSAALRFCIDDAFHGLVREI 181 >gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo sapiens] Length = 189 Score = 62.4 bits (150), Expect = 3e-10 Identities = 52/187 (27%), Positives = 93/187 (49%), Gaps = 13/187 (6%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ Y++ V+GA GVGKSA+ Q + N F + P T Y VV++G L ILD Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDP-TIEDSYRKQVVIDGETCLLDILD-- 57 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +E++ + +R+ ++ V+ I SF + R+QI RV + + Sbjct: 58 ------TAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI--KRVKDSDDV 109 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCAR 181 P+++VGNK DL V + +H + K++ ++E SAK + F L++ + R Sbjct: 110 PMVLVGNKCDLPTRTVDTK--QAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYR 167 Query: 182 CKHVHAA 188 K ++++ Sbjct: 168 MKKLNSS 174 >gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 61.6 bits (148), Expect = 4e-10 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 29/200 (14%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ Y++ V+GA GVGKSA+ Q + N F + P T Y VV++G L ILD Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDP-TIEDSYRKQVVIDGETCLLDILD-- 57 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +E++ + +R+ ++ V+ I SFE + R+QI RV + + Sbjct: 58 ------TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--KRVKDSDDV 109 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV---- 177 P+++VGNK DL R + L R ++ Y+E SAK + F L++ + Sbjct: 110 PMVLVGNKCDL-AARTVESRQAQDLAR-SYGIPYIETSAKTRQGVEDAFYTLVREIRQHK 167 Query: 178 ------------GCARCKHV 185 GC CK V Sbjct: 168 LRKLNPPDESGPGCMSCKCV 187 >gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 1 [Homo sapiens] Length = 189 Score = 61.6 bits (148), Expect = 4e-10 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 29/200 (14%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ Y++ V+GA GVGKSA+ Q + N F + P T Y VV++G L ILD Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDP-TIEDSYRKQVVIDGETCLLDILD-- 57 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +E++ + +R+ ++ V+ I SFE + R+QI RV + + Sbjct: 58 ------TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--KRVKDSDDV 109 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV---- 177 P+++VGNK DL R + L R ++ Y+E SAK + F L++ + Sbjct: 110 PMVLVGNKCDL-AARTVESRQAQDLAR-SYGIPYIETSAKTRQGVEDAFYTLVREIRQHK 167 Query: 178 ------------GCARCKHV 185 GC CK V Sbjct: 168 LRKLNPPDESGPGCMSCKCV 187 >gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog isoform 2 [Homo sapiens] Length = 170 Score = 60.5 bits (145), Expect = 1e-09 Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 13/160 (8%) Query: 2 VSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFP 61 ++ Y++ V+GA GVGKSA+ Q + N F + P T Y VV++G L ILD Sbjct: 1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDP-TIEDSYRKQVVIDGETCLLDILD-- 57 Query: 62 PISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSET 121 +E++ + +R+ ++ V+ I SFE + R+QI RV + + Sbjct: 58 ------TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--KRVKDSDDV 109 Query: 122 PIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAK 161 P+++VGNK DL R + L R ++ Y+E SAK Sbjct: 110 PMVLVGNKCDL-AARTVESRQAQDLAR-SYGIPYIETSAK 147 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.329 0.140 0.455 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,353,472 Number of Sequences: 37866 Number of extensions: 299434 Number of successful extensions: 1172 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 94 Number of HSP's that attempted gapping in prelim test: 904 Number of HSP's gapped (non-prelim): 199 length of query: 203 length of database: 18,247,518 effective HSP length: 97 effective length of query: 106 effective length of database: 14,574,516 effective search space: 1544898696 effective search space used: 1544898696 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.