Search of human proteins with 15029520

Search of human proteins with 15029520

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15029520 histidyl-tRNA synthetase 2 precursor [Homo sapiens]
         (506 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15029520 histidyl-tRNA synthetase 2 precursor [Homo sapiens]      1011   0.0  
gi|6996014 histidyl-tRNA synthetase [Homo sapiens]                    741   0.0  
gi|65287717 eukaryotic translation initiation factor 2 alpha kin...   119   5e-27
gi|89886470 hypothetical protein LOC84960 [Homo sapiens]               31   3.0  
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ...    30   4.0  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        30   5.2  
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        30   5.2  

>gi|15029520 histidyl-tRNA synthetase 2 precursor [Homo sapiens]
          Length = 506

 Score = 1011 bits (2615), Expect = 0.0
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP 60
           MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP
Sbjct: 1   MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP 60

Query: 61  KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD 120
           KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD
Sbjct: 61  KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD 120

Query: 121 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA 180
           QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA
Sbjct: 121 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA 180

Query: 181 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID 240
           GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID
Sbjct: 181 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID 240

Query: 241 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL 300
           KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL
Sbjct: 241 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL 300

Query: 301 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA 360
           GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA
Sbjct: 301 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA 360

Query: 361 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN 420
           GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN
Sbjct: 361 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN 420

Query: 421 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR 480
           FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR
Sbjct: 421 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR 480

Query: 481 SVASREEVAIKRENFVAEIQKRLSES 506
           SVASREEVAIKRENFVAEIQKRLSES
Sbjct: 481 SVASREEVAIKRENFVAEIQKRLSES 506


>gi|6996014 histidyl-tRNA synthetase [Homo sapiens]
          Length = 509

 Score =  741 bits (1912), Expect = 0.0
 Identities = 361/473 (76%), Positives = 416/473 (87%), Gaps = 1/473 (0%)

Query: 34  QSQVAEAV-LTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKG 92
           + +VA+ + L +QL   + K  F++KTPKGTRD SP+ M VREK+ D++I CFKRHGA+ 
Sbjct: 32  EEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEV 91

Query: 93  MDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYH 152
           +DTP FELKETL  KYGEDS L+YDLKDQGGELLSLRYDLTVPFARYLAMNK+  +KRYH
Sbjct: 92  IDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYH 151

Query: 153 VGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKV 212
           + KV+RR++P + +GRYREF QCDFDIAG FDPMIPDAECLKIMCEILS LQ+GDFL+KV
Sbjct: 152 IAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKV 211

Query: 213 NDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYV 272
           NDRRI+DGMFA+CGV +SKFR ICSS+DKLDK++W++V++EMV +KGLAPEVADRIGDYV
Sbjct: 212 NDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYV 271

Query: 273 QCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYY 332
           Q HGGVSLVEQ+ QDP+LSQNKQALEGLGDLKLLFEYLTLFGI DKISFDLSLARGLDYY
Sbjct: 272 QQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYY 331

Query: 333 TGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFY 392
           TGVIYEAVLLQTP QAGEEPL VGSVAAGGRYDGLVGMFDPKG KVPCVGLSIGVERIF 
Sbjct: 332 TGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFS 391

Query: 393 IVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQ 452
           IVEQR++   EK+RTTETQV VA+ QK  L+ERLKL++ELWD+GIKAE+LYK NPKLL Q
Sbjct: 392 IVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQ 451

Query: 453 LHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSE 505
           L YCE  GIPLV IIGEQELK+GVIK+RSV SREEV ++RE+ V EI++R  +
Sbjct: 452 LQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ 504


>gi|65287717 eukaryotic translation initiation factor 2 alpha kinase 4
            [Homo sapiens]
          Length = 1649

 Score =  119 bits (299), Expect = 5e-27
 Identities = 114/470 (24%), Positives = 204/470 (43%), Gaps = 50/470 (10%)

Query: 52   KPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGED 111
            K NF I+T K           +++ + + +I  FKRHGA  + TP    +     ++ E 
Sbjct: 1053 KGNFSIRTAK-----------MQQHVCETIIRIFKRHGAVQLCTPLLLPRNRQIYEHNEA 1101

Query: 112  SGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYRE 171
            +  M    D  G L+ L +DL +PFARY+A N +  +KRY + +V+R     + +   +E
Sbjct: 1102 ALFM----DHSGMLVMLPFDLRIPFARYVARNNILNLKRYCIERVFRPRK--LDRFHPKE 1155

Query: 172  FCQCDFDI-AGQFDPMIPDAECLKIMCEILS---GLQLGDFLIKVNDRRIVDGMFAVCGV 227
              +C FDI     +  +P AE +  + EI+     LQ  ++ I +N   ++  +   CG+
Sbjct: 1156 LLECAFDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGI 1215

Query: 228  PESKFRAICSSIDKLDKMAWKDVRHEMVVK---KGLAPEVADRIGDYVQCHGGV------ 278
            PE K   +   I   D +  K  R E+  K     L+     R+  +++  G +      
Sbjct: 1216 PEDKLSQV--YIILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKFIEQKGDLQDLMPT 1273

Query: 279  --SLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVI 336
              SL++Q     +L +      GL DL+ +   L   GI  ++  +L L   +  + G+I
Sbjct: 1274 INSLIKQKTGIAQLVK-----YGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGII 1328

Query: 337  YEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMF---DPKGHKVPCVGLSIGVERIFYI 393
            ++ V      Q     +    +AAGGRYD L+  F      G     +G+SI +++I   
Sbjct: 1329 FQFVAFIKRRQRAVPEI----LAAGGRYDLLIPQFRGPQALGPVPTAIGVSIAIDKI--- 1381

Query: 394  VEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQL 453
                +    E V  +   + V +  +  +   + L  +LW +GI AE++Y  +       
Sbjct: 1382 -SAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQ 1440

Query: 454  HYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRL 503
             YC    I  V ++ ++E     +K      + E  +     V  + ++L
Sbjct: 1441 EYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 1490


>gi|89886470 hypothetical protein LOC84960 [Homo sapiens]
          Length = 534

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 12/116 (10%)

Query: 398 MKTKGEKVRTTETQVFVATPQKNF--LQERLKLI---AELWDSGIKAEMLYKNNPK--LL 450
           M T+  K+R  ET       Q     + E++K     + +WD  I +  L + N +  L 
Sbjct: 276 MSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWD--ITSRFLAQRNTEENLE 333

Query: 451 TQLHYCESTGIPLVVIIGEQELKEGVIKIR---SVASREEVAIKRENFVAEIQKRL 503
            Q+  CE   + L  ++ + EL+E V+K R   S  S + V  K  + + E ++RL
Sbjct: 334 LQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERL 389


>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
            [Homo sapiens]
          Length = 2671

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 32   RCQSQVAEAVLTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAK 91
            RC   +A   L+  L + Q KP F    P    D  P    VR+ +LD  ++    HG +
Sbjct: 1234 RCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRHPD---VRKCMLDAALATLNTHGKE 1290

Query: 92   GMDT--PAFE 99
             +++  P FE
Sbjct: 1291 NVNSLLPVFE 1300


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 27/117 (23%), Positives = 56/117 (47%), Gaps = 9/117 (7%)

Query: 392 YIVEQRMKTKGEKVRTTETQV--FVATPQ-KNFLQERLKLIAELWDSGIKAEMLYKNNPK 448
           Y+V +R K +       ++ +  F+A  + +  L+E   +I +    G  A   YK +  
Sbjct: 828 YVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 449 LLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSE 505
            +  L  C         ++ ++ELK+  I+ RSV   +++ I  EN + ++Q+++ E
Sbjct: 888 AIIYLQCCFRR------MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 27/117 (23%), Positives = 56/117 (47%), Gaps = 9/117 (7%)

Query: 392 YIVEQRMKTKGEKVRTTETQV--FVATPQ-KNFLQERLKLIAELWDSGIKAEMLYKNNPK 448
           Y+V +R K +       ++ +  F+A  + +  L+E   +I +    G  A   YK +  
Sbjct: 828 YVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 449 LLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSE 505
            +  L  C         ++ ++ELK+  I+ RSV   +++ I  EN + ++Q+++ E
Sbjct: 888 AIIYLQCCFRR------MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,595,721
Number of Sequences: 37866
Number of extensions: 808469
Number of successful extensions: 1629
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1616
Number of HSP's gapped (non-prelim): 10
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.