BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110225349 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform B [Homo sapiens] (335 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 673 0.0 gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 497 e-141 gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 252 4e-67 gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 220 2e-57 gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 216 2e-56 gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 216 2e-56 gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 206 2e-53 gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 186 3e-47 gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 175 4e-44 gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 175 4e-44 gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 175 4e-44 gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 175 4e-44 gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 169 4e-42 gi|73858566 heparin cofactor II precursor [Homo sapiens] 154 8e-38 gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 144 1e-34 gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 143 2e-34 gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 143 2e-34 gi|170295807 neuroserpin precursor [Homo sapiens] 141 7e-34 gi|4826904 neuroserpin precursor [Homo sapiens] 141 7e-34 gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 140 2e-33 gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 140 2e-33 gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 138 6e-33 gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 137 1e-32 >gi|110225349 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform B [Homo sapiens] Length = 335 Score = 673 bits (1736), Expect = 0.0 Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS Sbjct: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60 Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL 120 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL Sbjct: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL 120 Query: 121 VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD 180 VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD Sbjct: 121 VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD 180 Query: 181 YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL 240 YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL Sbjct: 181 YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL 240 Query: 241 PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP 300 PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP Sbjct: 241 PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP 300 Query: 301 SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 335 SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS Sbjct: 301 SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 335 >gi|110225347 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform A [Homo sapiens] Length = 435 Score = 497 bits (1279), Expect = e-141 Identities = 251/264 (95%), Positives = 252/264 (95%) Query: 72 RLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 131 RLY V T N + ARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE Sbjct: 172 RLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 231 Query: 132 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 191 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL Sbjct: 232 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 291 Query: 192 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 251 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK Sbjct: 292 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 351 Query: 252 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 311 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF Sbjct: 352 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 411 Query: 312 LMMITNKATDGILFLGKVENPTKS 335 LMMITNKATDGILFLGKVENPTKS Sbjct: 412 LMMITNKATDGILFLGKVENPTKS 435 Score = 191 bits (484), Expect = 1e-48 Identities = 95/116 (81%), Positives = 101/116 (87%), Gaps = 4/116 (3%) Query: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS Sbjct: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60 Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGL 112 QVYSLNTDFAFRLYRRLVLETPSQNIFFSP +++ + + G I+QGL Sbjct: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGL 116 >gi|205277441 serine (or cysteine) proteinase inhibitor, clade A, member 7 [Homo sapiens] Length = 415 Score = 252 bits (643), Expect = 4e-67 Identities = 126/263 (47%), Positives = 179/263 (68%) Query: 73 LYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEK 132 LY V T NI + INSHV+ +T+GKVV +IQ L T MVLVN+I FKA+W Sbjct: 153 LYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWAN 212 Query: 133 PFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLP 192 PF P T + FL+ + TV VPMMHQ EQ+ VD ELNC VLQMDY +A+A FVLP Sbjct: 213 PFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLP 272 Query: 193 SKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN 252 +G+M +E A+S++TL+KW+ LQK W+++F+P+FSISA+Y+L L KMGIQ+ + +N Sbjct: 273 KEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 332 Query: 253 ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFL 312 ADFSG+ + + L++S A HKAVL + E+GTEA A + + ++ + + +R+F+ Sbjct: 333 ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFM 392 Query: 313 MMITNKATDGILFLGKVENPTKS 335 ++I ++T ILFLGKV NPT++ Sbjct: 393 LLILERSTRSILFLGKVVNPTEA 415 Score = 68.2 bits (165), Expect = 1e-11 Identities = 45/115 (39%), Positives = 65/115 (56%), Gaps = 11/115 (9%) Query: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78 M+ +LY VL +GL A I+C SP +A SS + ++ S+N DFAF LYRR Sbjct: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACH--SSQPNATLYKMSSINADFAFNLYRRFT 58 Query: 79 LETPSQNIFFSPARINSHVKK-------KTQGKVVDIIQGLDLL-TAMVLVNHIF 125 +ETP +NIFFSP I++ + TQ ++V+ + G +L T MV + H F Sbjct: 59 VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL-GFNLTDTPMVEIQHGF 112 >gi|194018472 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 [Homo sapiens] Length = 406 Score = 220 bits (560), Expect = 2e-57 Identities = 114/241 (47%), Positives = 164/241 (68%), Gaps = 5/241 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V K+T+GK+VD+++ LD +++VN+IFFKAKWE F+ + T++ F V + Sbjct: 171 QINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSET 229 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 V VPMM +++Q+ + +D L+C V+ + Y+G+A A F+LPS+GKM+Q+E LS +TLRK Sbjct: 230 VVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRK 289 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 W +KR +E+++P+FSI SY LE +LP +GI NVF +AD SGI+ ++QVS+ H Sbjct: 290 WLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVH 349 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAV++V E GT A AAT T F RS S V FNR FLM I + + ILFLGKV Sbjct: 350 KAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNR 405 Query: 332 P 332 P Sbjct: 406 P 406 Score = 37.4 bits (85), Expect = 0.019 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGLDL 114 S DF F LYR L PSQ+IFFSP I+ + + G + I++GL L Sbjct: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGL 97 >gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 [Homo sapiens] Length = 427 Score = 216 bits (550), Expect = 2e-56 Identities = 119/247 (48%), Positives = 163/247 (65%), Gaps = 7/247 (2%) Query: 93 INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152 IN HVKK+T+GK+VD++ L MVLVN+I+FKA WEKPF T F V E T Sbjct: 182 INDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTT 240 Query: 153 VHVPMMHQKEQFAFGV-DTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 V VPMM Q ++ + + D L C VL+MDYKGDA FF+LP++GKMR++E+ L+ L + Sbjct: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300 Query: 212 WSHSLQKR----WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVS 267 W++ L+KR +E+ +P+FSIS SY L+ ILP++G ++F K AD SGI K+ L+ S Sbjct: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360 Query: 268 KATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLG 327 K+ HKA LDV E GTEA AAT+ S + + FNR FL++I + +T +LFLG Sbjct: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLG 419 Query: 328 KVENPTK 334 KV +PTK Sbjct: 420 KVVDPTK 426 Score = 42.7 bits (99), Expect = 5e-04 Identities = 18/41 (43%), Positives = 27/41 (65%) Query: 55 KSTPASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINS 95 + +P+ ++ N DFAFR Y + ETP +NIFFSP I++ Sbjct: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISA 84 >gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 [Homo sapiens] Length = 422 Score = 216 bits (550), Expect = 2e-56 Identities = 111/241 (46%), Positives = 159/241 (65%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +++++T G+VVD + T MVL N+IFFKAKW+ PF T+K F V E+ Sbjct: 179 QINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 ++ VPMMHQKE F D +L C VLQ++Y+G+A+A VLP GKM+Q+E AL +TLRK Sbjct: 239 SLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 W L +++ +PRFSIS +YNLE ILP++G+ N+ + ADFSG+ + + +SK +H Sbjct: 299 WGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KA++D+SE+GTEA AA+ S + S FNR FL+++ T +LFLGKV N Sbjct: 359 KAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418 Query: 332 P 332 P Sbjct: 419 P 419 Score = 35.0 bits (79), Expect = 0.094 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 8/76 (10%) Query: 27 LFAVGLCAPIYC---VSPANAPSAYPRPSSTK-STPASQVYSLN---TDFAFRLYRRLVL 79 L G+ A ++C ++ + P+P + S PA + + T+FA RLY+ L Sbjct: 8 LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67 Query: 80 ETPSQNIFFSPARINS 95 + P NIFFSP I++ Sbjct: 68 DAPG-NIFFSPVSIST 82 >gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor [Homo sapiens] Length = 423 Score = 206 bits (524), Expect = 2e-53 Identities = 120/271 (44%), Positives = 164/271 (60%), Gaps = 3/271 (1%) Query: 67 TDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFF 126 T+ A RLY T Q+ + IN +VK T+GK+ D+I+ LD T MVLVN+IFF Sbjct: 154 TEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFF 213 Query: 127 KAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKE-QFAFGVDTELNCFVLQMDYKGDA 185 KAKWE PF P+ T ++ F + ++ V VPMM + D EL+C V+++ Y G+A Sbjct: 214 KAKWEMPFDPQDTHQS-RFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA 272 Query: 186 VAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI-EVFIPRFSISASYNLETILPKMG 244 A F+LP + KM ++E L TL++W SL+ R I E+++P+FSIS YNL IL ++G Sbjct: 273 SALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLG 332 Query: 245 IQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFT 304 I+ F AD SGI +L VS+ HKAVLDV EEGTEA+AAT K + S + Sbjct: 333 IEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTI 392 Query: 305 VSFNRTFLMMITNKATDGILFLGKVENPTKS 335 V FNR FLM+I T I F+ KV NP ++ Sbjct: 393 VRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA 423 Score = 44.7 bits (104), Expect = 1e-04 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 27 LFAVGLCAPIYCV--SPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ 84 L A G C + C SP + + + + S N DFAF LY++LVL+ P + Sbjct: 12 LLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDK 71 Query: 85 NIFFSPARINSHVKKKTQG----KVVDIIQGL 112 N+ FSP I++ + + G + +I++GL Sbjct: 72 NVIFSPLSISTALAFLSLGAHNTTLTEILKGL 103 >gi|73858564 corticosteroid binding globulin precursor [Homo sapiens] Length = 405 Score = 186 bits (472), Expect = 3e-47 Identities = 105/259 (40%), Positives = 150/259 (57%), Gaps = 5/259 (1%) Query: 74 YRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKP 133 Y VL Q+ + +INS+VK KTQGK+VD+ GLD +VLVN+IFFK W +P Sbjct: 151 YESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQP 210 Query: 134 FHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPS 193 F TR+ F V E V VPMM Q ++ D EL C ++QM+Y G+ FF+LP Sbjct: 211 FDLASTREE-NFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPD 269 Query: 194 KGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNA 253 KGKM + ALS T+ +WS L ++++IP+ +IS Y+L +L +MGI ++F A Sbjct: 270 KGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQA 329 Query: 254 DFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLM 313 +FS I + L+ SK HKAVL ++EEG + +T + SK + FN+ F++ Sbjct: 330 NFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFII 385 Query: 314 MITNKATDGILFLGKVENP 332 MI + T LFL +V NP Sbjct: 386 MIFDHFTWSSLFLARVMNP 404 Score = 38.5 bits (88), Expect = 0.009 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 4/53 (7%) Query: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKV----VDIIQGL 112 S N DFAF LY+ LV +P +NIF SP I+ + + G ++QGL Sbjct: 41 SANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGL 93 >gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 175 bits (444), Expect = 4e-44 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%) Query: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151 +IN +V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238 Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211 TV VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271 + + +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA H Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358 Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331 KAVL + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV N Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414 Query: 332 PTK 334 PT+ Sbjct: 415 PTQ 417 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74 +S +G+L GLC P+ +A +S + P + N +FAF LY Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62 Query: 75 RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113 R+L ++ S NIFFSP I + + G D I++GL+ Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105 >gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 [Homo sapiens] Length = 414 Score = 169 bits (427), Expect = 4e-42 Identities = 84/263 (31%), Positives = 152/263 (57%), Gaps = 5/263 (1%) Query: 70 AFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAK 129 A Y + T QN+ + +IN + +KT GK+ ++I+ +D T M+L N+IFF+A+ Sbjct: 154 AKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRAR 213 Query: 130 WEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFF 189 W+ F P T++ F + + +V VPMM + + G D +L+C +L++ Y+ + A F Sbjct: 214 WKHEFDPNVTKEE-DFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIF 272 Query: 190 VLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVF 249 +LP +GK++ LE+ L T +W L +R ++V +PR ++ +++L+ L +G+ +F Sbjct: 273 ILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIF 332 Query: 250 DKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNR 309 +++ D + IA SL+V +A HKA L + E GTE A T + + + V ++ Sbjct: 333 EEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPME----TPLVVKIDK 388 Query: 310 TFLMMITNKATDGILFLGKVENP 332 +L++I ++ +LFLGK+ NP Sbjct: 389 PYLLLIYSEKIPSVLFLGKIVNP 411 Score = 35.0 bits (79), Expect = 0.094 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78 +A +L +L GL P + SP N + + A ++ N D F+L ++L Sbjct: 7 LAIFLAVLLTVKGLLKPSF--SPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLA 64 Query: 79 LETPSQNIFFSPARINS 95 P +NIF SP I++ Sbjct: 65 FYNPGRNIFLSPLSIST 81 >gi|73858566 heparin cofactor II precursor [Homo sapiens] Length = 499 Score = 154 bits (390), Expect = 8e-38 Identities = 89/246 (36%), Positives = 138/246 (56%), Gaps = 7/246 (2%) Query: 91 ARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150 ++ N+H+ K T+G + D ++ +D T M+++N I+FK W F E T N F + E+ Sbjct: 260 SKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH-NHNFRLNER 318 Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTL 209 V V MM K F D EL+C +LQ++Y G V+P K M+ LE L+ R + Sbjct: 319 EVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVV 378 Query: 210 RKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKA 269 +W S+ R EV +P+F + +YNL L MGI+ +FDKN + +GI+ + + + Sbjct: 379 ERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQ-RIAIDLF 437 Query: 270 THKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKV 329 H+ + V+EEGT+AT TT F+ S FTV +R FL +I T +LF+G+V Sbjct: 438 KHQGTITVNEEGTQATTVTTVGFMPLSTQ--VRFTV--DRPFLFLIYEHRTSCLLFMGRV 493 Query: 330 ENPTKS 335 NP++S Sbjct: 494 ANPSRS 499 >gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo sapiens] Length = 392 Score = 144 bits (362), Expect = 1e-34 Identities = 90/247 (36%), Positives = 139/247 (56%), Gaps = 10/247 (4%) Query: 93 INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150 IN+ V+ KT GKV ++ +D + MVLVN I+FK +W+ F T K+ PF + E Sbjct: 149 INAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKS-PFQLSEG 207 Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKG--KMRQLEQALSART 208 V V MM+Q F E VL++ Y + ++ +L G ++Q+E+ L++ T Sbjct: 208 KNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGT 267 Query: 209 LRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQ 265 +W+ S + +R +EV +PRF + Y L ++L +G+ ++F++ AD SG++ L Sbjct: 268 FHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLY 327 Query: 266 VSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILF 325 +SKA HK+ LDVSEEGTEA AAT V+S + F N FL I + T+ ILF Sbjct: 328 LSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKA--NHPFLFFIRHTHTNTILF 385 Query: 326 LGKVENP 332 GK+ +P Sbjct: 386 CGKLASP 392 >gi|219689110 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 [Homo sapiens] Length = 415 Score = 143 bits (360), Expect = 2e-34 Identities = 87/251 (34%), Positives = 142/251 (56%), Gaps = 13/251 (5%) Query: 92 RINSHVKKKTQGKVVDIIQ--GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGE 149 +INS VK +T+GK+ +++ +D T MVLVN ++FK KW+ PF + +PF V Sbjct: 168 KINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNS 226 Query: 150 QVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQAL 204 V MM+ +E+ G +L +L++ Y GD F +LP + + LE + Sbjct: 227 AQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEI 286 Query: 205 SARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261 + L KW+ + + +EV+IP+F + Y L +IL MG+++ F+K A+FSG+++R Sbjct: 287 TYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSER 346 Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321 + L +S+ H+A++DV+EEGTEA A T R+ G F + FL +I +K T+ Sbjct: 347 NDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITN 404 Query: 322 GILFLGKVENP 332 ILF G+ +P Sbjct: 405 CILFFGRFSSP 415 Score = 32.0 bits (71), Expect = 0.80 Identities = 14/30 (46%), Positives = 20/30 (66%) Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPARINS 95 NT FA L++ L +P+QN+F SP I+S Sbjct: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISS 37 >gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 [Homo sapiens] Length = 415 Score = 143 bits (360), Expect = 2e-34 Identities = 87/251 (34%), Positives = 142/251 (56%), Gaps = 13/251 (5%) Query: 92 RINSHVKKKTQGKVVDIIQ--GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGE 149 +INS VK +T+GK+ +++ +D T MVLVN ++FK KW+ PF + +PF V Sbjct: 168 KINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNS 226 Query: 150 QVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQAL 204 V MM+ +E+ G +L +L++ Y GD F +LP + + LE + Sbjct: 227 AQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEI 286 Query: 205 SARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261 + L KW+ + + +EV+IP+F + Y L +IL MG+++ F+K A+FSG+++R Sbjct: 287 TYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSER 346 Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321 + L +S+ H+A++DV+EEGTEA A T R+ G F + FL +I +K T+ Sbjct: 347 NDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITN 404 Query: 322 GILFLGKVENP 332 ILF G+ +P Sbjct: 405 CILFFGRFSSP 415 Score = 32.0 bits (71), Expect = 0.80 Identities = 14/30 (46%), Positives = 20/30 (66%) Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPARINS 95 NT FA L++ L +P+QN+F SP I+S Sbjct: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISS 37 >gi|170295807 neuroserpin precursor [Homo sapiens] Length = 410 Score = 141 bits (356), Expect = 7e-34 Identities = 79/250 (31%), Positives = 146/250 (58%), Gaps = 13/250 (5%) Query: 93 INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150 IN V+ T V D++ + D T + L+N ++FK W+ F PE TR F F ++ Sbjct: 151 INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFSFTKDDE 209 Query: 151 VTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK--MRQLEQ 202 V +PMM+Q+ +F +G ++ + VL++ Y+GD ++ ++ S+ + + LE Sbjct: 210 SEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEP 269 Query: 203 ALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRD 262 + A+ + +W++S++K+ +EV++PRF++ +L+ +L +GI +F K+A+ +G++ Sbjct: 270 LVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNK 329 Query: 263 SLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDG 322 + +SKA HK+ L+V+EEG+E AA + I S+ Y V + F +I N+ T Sbjct: 330 EIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGT 387 Query: 323 ILFLGKVENP 332 ILF+G+V +P Sbjct: 388 ILFMGRVMHP 397 >gi|4826904 neuroserpin precursor [Homo sapiens] Length = 410 Score = 141 bits (356), Expect = 7e-34 Identities = 79/250 (31%), Positives = 146/250 (58%), Gaps = 13/250 (5%) Query: 93 INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150 IN V+ T V D++ + D T + L+N ++FK W+ F PE TR F F ++ Sbjct: 151 INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFSFTKDDE 209 Query: 151 VTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK--MRQLEQ 202 V +PMM+Q+ +F +G ++ + VL++ Y+GD ++ ++ S+ + + LE Sbjct: 210 SEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEP 269 Query: 203 ALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRD 262 + A+ + +W++S++K+ +EV++PRF++ +L+ +L +GI +F K+A+ +G++ Sbjct: 270 LVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNK 329 Query: 263 SLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDG 322 + +SKA HK+ L+V+EEG+E AA + I S+ Y V + F +I N+ T Sbjct: 330 EIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGT 387 Query: 323 ILFLGKVENP 332 ILF+G+V +P Sbjct: 388 ILFMGRVMHP 397 >gi|154759291 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 [Homo sapiens] Length = 444 Score = 140 bits (352), Expect = 2e-33 Identities = 81/243 (33%), Positives = 132/243 (54%), Gaps = 7/243 (2%) Query: 93 INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152 +N ++ K+T+GK+ + ++ T ++LV++I FK KW PF P +T + F + + T Sbjct: 205 MNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVD-TFHLDKYKT 263 Query: 153 VHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTLRK 211 + VPMM+ +FA D C VL++ Y+G+A VL K G LE L+ + Sbjct: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI-AKRDSLQVSKAT 270 W +++ R +EVF P+F + Y + +L +MGI+ +F AD S + A +LQVS+ Sbjct: 324 WLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVL 383 Query: 271 HKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVE 330 + V++V E GTEA A ++ S + +R F MI + + +LFLG+V Sbjct: 384 QRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYEETSGMLLFLGRVV 439 Query: 331 NPT 333 NPT Sbjct: 440 NPT 442 >gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 [Homo sapiens] Length = 444 Score = 140 bits (352), Expect = 2e-33 Identities = 81/243 (33%), Positives = 132/243 (54%), Gaps = 7/243 (2%) Query: 93 INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152 +N ++ K+T+GK+ + ++ T ++LV++I FK KW PF P +T + F + + T Sbjct: 205 MNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVD-TFHLDKYKT 263 Query: 153 VHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTLRK 211 + VPMM+ +FA D C VL++ Y+G+A VL K G LE L+ + Sbjct: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323 Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI-AKRDSLQVSKAT 270 W +++ R +EVF P+F + Y + +L +MGI+ +F AD S + A +LQVS+ Sbjct: 324 WLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVL 383 Query: 271 HKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVE 330 + V++V E GTEA A ++ S + +R F MI + + +LFLG+V Sbjct: 384 QRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYEETSGMLLFLGRVV 439 Query: 331 NPT 333 NPT Sbjct: 440 NPT 442 >gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo sapiens] Length = 464 Score = 138 bits (348), Expect = 6e-33 Identities = 91/256 (35%), Positives = 143/256 (55%), Gaps = 10/256 (3%) Query: 84 QNIFFSPARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRK 141 +N S A IN V KT+G++ D+I + ++ LT +VLVN I+FK W+ F PE TRK Sbjct: 209 ENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRK 268 Query: 142 NFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAF-FVLPSKGK-MRQ 199 F + + MM+Q+ +F + E VL++ +KGD + +LP K + + Sbjct: 269 EL-FYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAK 326 Query: 200 LEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFD-KNADFSGI 258 +E+ L+ L++W L++ + V +PRF I ++L+ L MG+ ++F + + GI Sbjct: 327 VEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGI 386 Query: 259 AK--RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMIT 316 RD L VS A HKA L+V+EEG+EA A+T RS + P+ T NR FL+ I Sbjct: 387 VAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLN-PNRVTFKANRPFLVFIR 445 Query: 317 NKATDGILFLGKVENP 332 + I+F+G+V NP Sbjct: 446 EVPLNTIIFMGRVANP 461 >gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 [Homo sapiens] Length = 379 Score = 137 bits (346), Expect = 1e-32 Identities = 84/251 (33%), Positives = 143/251 (56%), Gaps = 14/251 (5%) Query: 93 INSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150 IN VK +T+GK+ +++ +D +T +VLVN I+FK W+ F E T N PF + ++ Sbjct: 132 INQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATT-NAPFRLNKK 190 Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL------PSKGKMRQLEQAL 204 V MM+QK++FA+G +L C VL++ Y+G+ ++ +L ++++E+ L Sbjct: 191 DRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQL 250 Query: 205 SARTLRKWSHSLQKRWIE--VFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261 + L +W+ +IE V +PRF + SY L + L ++G+Q++F+ + AD SG++ Sbjct: 251 TLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGA 310 Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321 + +SK HK+ ++V+EEGTEA AAT FT + FL I + ++ Sbjct: 311 RDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--DHPFLFFIRHNSSG 368 Query: 322 GILFLGKVENP 332 ILFLG+ +P Sbjct: 369 SILFLGRFSSP 379 Score = 30.0 bits (66), Expect = 3.0 Identities = 16/35 (45%), Positives = 20/35 (57%) Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINS 95 Q+ S NT FA L+ L P+ NIF SP I+S Sbjct: 3 QLSSANTRFALDLFLALSENNPAGNIFISPFSISS 37 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.134 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,962,078 Number of Sequences: 37866 Number of extensions: 507383 Number of successful extensions: 1652 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 1413 Number of HSP's gapped (non-prelim): 107 length of query: 335 length of database: 18,247,518 effective HSP length: 103 effective length of query: 232 effective length of database: 14,347,320 effective search space: 3328578240 effective search space used: 3328578240 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.