Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 110225349

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform B [Homo
sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ...   673   0.0  
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   497   e-141
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,...   252   4e-67
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   220   2e-57
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (...   216   2e-56
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr...   216   2e-56
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   206   2e-53
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   186   3e-47
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom...   175   4e-44
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo...   175   4e-44
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo...   175   4e-44
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo...   175   4e-44
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (...   169   4e-42
gi|73858566 heparin cofactor II precursor [Homo sapiens]              154   8e-38
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   144   1e-34
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   143   2e-34
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   143   2e-34
gi|170295807 neuroserpin precursor [Homo sapiens]                     141   7e-34
gi|4826904 neuroserpin precursor [Homo sapiens]                       141   7e-34
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...   140   2e-33
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...   140   2e-33
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   138   6e-33
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   137   1e-32

>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           B [Homo sapiens]
          Length = 335

 Score =  673 bits (1736), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
           MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS
Sbjct: 1   MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60

Query: 61  QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL 120
           QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL
Sbjct: 61  QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVL 120

Query: 121 VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD 180
           VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD
Sbjct: 121 VNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMD 180

Query: 181 YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL 240
           YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL
Sbjct: 181 YKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETIL 240

Query: 241 PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP 300
           PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP
Sbjct: 241 PKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGP 300

Query: 301 SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 335
           SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS
Sbjct: 301 SYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 335


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  497 bits (1279), Expect = e-141
 Identities = 251/264 (95%), Positives = 252/264 (95%)

Query: 72  RLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 131
           RLY   V  T   N   + ARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE
Sbjct: 172 RLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 231

Query: 132 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 191
           KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL
Sbjct: 232 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 291

Query: 192 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 251
           PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK
Sbjct: 292 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 351

Query: 252 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 311
           NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF
Sbjct: 352 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 411

Query: 312 LMMITNKATDGILFLGKVENPTKS 335
           LMMITNKATDGILFLGKVENPTKS
Sbjct: 412 LMMITNKATDGILFLGKVENPTKS 435



 Score =  191 bits (484), Expect = 1e-48
 Identities = 95/116 (81%), Positives = 101/116 (87%), Gaps = 4/116 (3%)

Query: 1   MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
           MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS
Sbjct: 1   MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60

Query: 61  QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGL 112
           QVYSLNTDFAFRLYRRLVLETPSQNIFFSP  +++ +   + G        I+QGL
Sbjct: 61  QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGL 116


>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
           member 7 [Homo sapiens]
          Length = 415

 Score =  252 bits (643), Expect = 4e-67
 Identities = 126/263 (47%), Positives = 179/263 (68%)

Query: 73  LYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEK 132
           LY   V  T   NI  +   INSHV+ +T+GKVV +IQ L   T MVLVN+I FKA+W  
Sbjct: 153 LYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWAN 212

Query: 133 PFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLP 192
           PF P  T  +  FL+ +  TV VPMMHQ EQ+   VD ELNC VLQMDY  +A+A FVLP
Sbjct: 213 PFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLP 272

Query: 193 SKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN 252
            +G+M  +E A+S++TL+KW+  LQK W+++F+P+FSISA+Y+L   L KMGIQ+ + +N
Sbjct: 273 KEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 332

Query: 253 ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFL 312
           ADFSG+ + + L++S A HKAVL + E+GTEA A    +   + ++   +  +  +R+F+
Sbjct: 333 ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFM 392

Query: 313 MMITNKATDGILFLGKVENPTKS 335
           ++I  ++T  ILFLGKV NPT++
Sbjct: 393 LLILERSTRSILFLGKVVNPTEA 415



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 45/115 (39%), Positives = 65/115 (56%), Gaps = 11/115 (9%)

Query: 19  MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
           M+ +LY VL  +GL A I+C SP    +A    SS  +    ++ S+N DFAF LYRR  
Sbjct: 1   MSPFLYLVLLVLGLHATIHCASPEGKVTACH--SSQPNATLYKMSSINADFAFNLYRRFT 58

Query: 79  LETPSQNIFFSPARINSHVKK-------KTQGKVVDIIQGLDLL-TAMVLVNHIF 125
           +ETP +NIFFSP  I++ +          TQ ++V+ + G +L  T MV + H F
Sbjct: 59  VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL-GFNLTDTPMVEIQHGF 112


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  220 bits (560), Expect = 2e-57
 Identities = 114/241 (47%), Positives = 164/241 (68%), Gaps = 5/241 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V K+T+GK+VD+++ LD    +++VN+IFFKAKWE  F+ + T++   F V  + 
Sbjct: 171 QINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSET 229

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
            V VPMM +++Q+ + +D  L+C V+ + Y+G+A A F+LPS+GKM+Q+E  LS +TLRK
Sbjct: 230 VVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRK 289

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           W    +KR +E+++P+FSI  SY LE +LP +GI NVF  +AD SGI+   ++QVS+  H
Sbjct: 290 WLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVH 349

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAV++V E GT A AAT T F  RS    S   V FNR FLM I +   + ILFLGKV  
Sbjct: 350 KAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNR 405

Query: 332 P 332
           P
Sbjct: 406 P 406



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 64  SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGLDL 114
           S   DF F LYR L    PSQ+IFFSP  I+  +   + G      + I++GL L
Sbjct: 43  SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGL 97


>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 4 [Homo
           sapiens]
          Length = 427

 Score =  216 bits (550), Expect = 2e-56
 Identities = 119/247 (48%), Positives = 163/247 (65%), Gaps = 7/247 (2%)

Query: 93  INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152
           IN HVKK+T+GK+VD++  L     MVLVN+I+FKA WEKPF    T     F V E  T
Sbjct: 182 INDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTT 240

Query: 153 VHVPMMHQKEQFAFGV-DTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           V VPMM Q ++  + + D  L C VL+MDYKGDA  FF+LP++GKMR++E+ L+   L +
Sbjct: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300

Query: 212 WSHSLQKR----WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVS 267
           W++ L+KR     +E+ +P+FSIS SY L+ ILP++G  ++F K AD SGI K+  L+ S
Sbjct: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360

Query: 268 KATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLG 327
           K+ HKA LDV E GTEA AAT+      S     +  + FNR FL++I + +T  +LFLG
Sbjct: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLG 419

Query: 328 KVENPTK 334
           KV +PTK
Sbjct: 420 KVVDPTK 426



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 18/41 (43%), Positives = 27/41 (65%)

Query: 55 KSTPASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINS 95
          + +P+ ++   N DFAFR Y  +  ETP +NIFFSP  I++
Sbjct: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISA 84


>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
           antiproteinase, antitrypsin), member 11 [Homo sapiens]
          Length = 422

 Score =  216 bits (550), Expect = 2e-56
 Identities = 111/241 (46%), Positives = 159/241 (65%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +++++T G+VVD +      T MVL N+IFFKAKW+ PF    T+K   F V E+ 
Sbjct: 179 QINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           ++ VPMMHQKE   F  D +L C VLQ++Y+G+A+A  VLP  GKM+Q+E AL  +TLRK
Sbjct: 239 SLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           W   L    +++ +PRFSIS +YNLE ILP++G+ N+ +  ADFSG+  + +  +SK +H
Sbjct: 299 WGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KA++D+SE+GTEA AA+       S +  S     FNR FL+++    T  +LFLGKV N
Sbjct: 359 KAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418

Query: 332 P 332
           P
Sbjct: 419 P 419



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 27 LFAVGLCAPIYC---VSPANAPSAYPRPSSTK-STPASQVYSLN---TDFAFRLYRRLVL 79
          L   G+ A ++C   ++  +     P+P   + S PA   + +    T+FA RLY+ L  
Sbjct: 8  LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67

Query: 80 ETPSQNIFFSPARINS 95
          + P  NIFFSP  I++
Sbjct: 68 DAPG-NIFFSPVSIST 82


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  206 bits (524), Expect = 2e-53
 Identities = 120/271 (44%), Positives = 164/271 (60%), Gaps = 3/271 (1%)

Query: 67  TDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFF 126
           T+ A RLY      T  Q+   +   IN +VK  T+GK+ D+I+ LD  T MVLVN+IFF
Sbjct: 154 TEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFF 213

Query: 127 KAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKE-QFAFGVDTELNCFVLQMDYKGDA 185
           KAKWE PF P+ T ++  F + ++  V VPMM        +  D EL+C V+++ Y G+A
Sbjct: 214 KAKWEMPFDPQDTHQS-RFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA 272

Query: 186 VAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI-EVFIPRFSISASYNLETILPKMG 244
            A F+LP + KM ++E  L   TL++W  SL+ R I E+++P+FSIS  YNL  IL ++G
Sbjct: 273 SALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLG 332

Query: 245 IQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFT 304
           I+  F   AD SGI    +L VS+  HKAVLDV EEGTEA+AAT  K  + S    +   
Sbjct: 333 IEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTI 392

Query: 305 VSFNRTFLMMITNKATDGILFLGKVENPTKS 335
           V FNR FLM+I    T  I F+ KV NP ++
Sbjct: 393 VRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA 423



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 27  LFAVGLCAPIYCV--SPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ 84
           L A G C  + C   SP +  +         +     + S N DFAF LY++LVL+ P +
Sbjct: 12  LLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDK 71

Query: 85  NIFFSPARINSHVKKKTQG----KVVDIIQGL 112
           N+ FSP  I++ +   + G     + +I++GL
Sbjct: 72  NVIFSPLSISTALAFLSLGAHNTTLTEILKGL 103


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  186 bits (472), Expect = 3e-47
 Identities = 105/259 (40%), Positives = 150/259 (57%), Gaps = 5/259 (1%)

Query: 74  YRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKP 133
           Y   VL    Q+   +  +INS+VK KTQGK+VD+  GLD    +VLVN+IFFK  W +P
Sbjct: 151 YESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQP 210

Query: 134 FHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPS 193
           F    TR+   F V E   V VPMM Q    ++  D EL C ++QM+Y G+   FF+LP 
Sbjct: 211 FDLASTREE-NFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPD 269

Query: 194 KGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNA 253
           KGKM  +  ALS  T+ +WS  L    ++++IP+ +IS  Y+L  +L +MGI ++F   A
Sbjct: 270 KGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQA 329

Query: 254 DFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLM 313
           +FS I +   L+ SK  HKAVL ++EEG +   +T     + SK       + FN+ F++
Sbjct: 330 NFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFII 385

Query: 314 MITNKATDGILFLGKVENP 332
           MI +  T   LFL +V NP
Sbjct: 386 MIFDHFTWSSLFLARVMNP 404



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 4/53 (7%)

Query: 64  SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKV----VDIIQGL 112
           S N DFAF LY+ LV  +P +NIF SP  I+  +   + G        ++QGL
Sbjct: 41  SANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGL 93


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (444), Expect = 4e-44
 Identities = 97/243 (39%), Positives = 147/243 (60%), Gaps = 5/243 (2%)

Query: 92  RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
           +IN +V+K TQGK+VD+++ LD  T   LVN+IFFK KWE+PF  + T +   F V +  
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVT 238

Query: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
           TV VPMM +   F      +L+ +VL M Y G+A A F LP +GK++ LE  L+   + K
Sbjct: 239 TVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
           +  +  +R   + +P+ SI+ +Y+L+++L ++GI  VF   AD SG+ +   L++SKA H
Sbjct: 299 FLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVH 358

Query: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
           KAVL + E+GTEA  A   + I  S        V FN+ F+ ++  + T   LF+GKV N
Sbjct: 359 KAVLTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVN 414

Query: 332 PTK 334
           PT+
Sbjct: 415 PTQ 417



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 20  ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
           +S  +G+L   GLC   P+         +A    +S   +  P     + N  +FAF LY
Sbjct: 3   SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62

Query: 75  RRLVLETPSQNIFFSPARINSHVKKKTQGKVVD----IIQGLD 113
           R+L  ++ S NIFFSP  I +     + G   D    I++GL+
Sbjct: 63  RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLN 105


>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 12 [Homo
           sapiens]
          Length = 414

 Score =  169 bits (427), Expect = 4e-42
 Identities = 84/263 (31%), Positives = 152/263 (57%), Gaps = 5/263 (1%)

Query: 70  AFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAK 129
           A   Y    + T  QN+  +  +IN  + +KT GK+ ++I+ +D  T M+L N+IFF+A+
Sbjct: 154 AKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRAR 213

Query: 130 WEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFF 189
           W+  F P  T++   F + +  +V VPMM +   +  G D +L+C +L++ Y+ +  A F
Sbjct: 214 WKHEFDPNVTKEE-DFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIF 272

Query: 190 VLPSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVF 249
           +LP +GK++ LE+ L   T  +W   L +R ++V +PR  ++ +++L+  L  +G+  +F
Sbjct: 273 ILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIF 332

Query: 250 DKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNR 309
           +++ D + IA   SL+V +A HKA L + E GTE  A T  + +       +   V  ++
Sbjct: 333 EEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPME----TPLVVKIDK 388

Query: 310 TFLMMITNKATDGILFLGKVENP 332
            +L++I ++    +LFLGK+ NP
Sbjct: 389 PYLLLIYSEKIPSVLFLGKIVNP 411



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
          +A +L  +L   GL  P +  SP N  +        +   A ++   N D  F+L ++L 
Sbjct: 7  LAIFLAVLLTVKGLLKPSF--SPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLA 64

Query: 79 LETPSQNIFFSPARINS 95
             P +NIF SP  I++
Sbjct: 65 FYNPGRNIFLSPLSIST 81


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  154 bits (390), Expect = 8e-38
 Identities = 89/246 (36%), Positives = 138/246 (56%), Gaps = 7/246 (2%)

Query: 91  ARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150
           ++ N+H+ K T+G + D ++ +D  T M+++N I+FK  W   F  E T  N  F + E+
Sbjct: 260 SKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTH-NHNFRLNER 318

Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTL 209
             V V MM  K  F    D EL+C +LQ++Y G      V+P K   M+ LE  L+ R +
Sbjct: 319 EVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVV 378

Query: 210 RKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKA 269
            +W  S+  R  EV +P+F +  +YNL   L  MGI+ +FDKN + +GI+ +  + +   
Sbjct: 379 ERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQ-RIAIDLF 437

Query: 270 THKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKV 329
            H+  + V+EEGT+AT  TT  F+  S      FTV  +R FL +I    T  +LF+G+V
Sbjct: 438 KHQGTITVNEEGTQATTVTTVGFMPLSTQ--VRFTV--DRPFLFLIYEHRTSCLLFMGRV 493

Query: 330 ENPTKS 335
            NP++S
Sbjct: 494 ANPSRS 499


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  144 bits (362), Expect = 1e-34
 Identities = 90/247 (36%), Positives = 139/247 (56%), Gaps = 10/247 (4%)

Query: 93  INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150
           IN+ V+ KT GKV ++     +D  + MVLVN I+FK +W+  F    T K+ PF + E 
Sbjct: 149 INAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKS-PFQLSEG 207

Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKG--KMRQLEQALSART 208
             V V MM+Q   F      E    VL++ Y  + ++  +L   G   ++Q+E+ L++ T
Sbjct: 208 KNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIANLKQIEKQLNSGT 267

Query: 209 LRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQ 265
             +W+ S  + +R +EV +PRF +   Y L ++L  +G+ ++F++  AD SG++    L 
Sbjct: 268 FHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLY 327

Query: 266 VSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILF 325
           +SKA HK+ LDVSEEGTEA AAT     V+S    + F    N  FL  I +  T+ ILF
Sbjct: 328 LSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQFKA--NHPFLFFIRHTHTNTILF 385

Query: 326 LGKVENP 332
            GK+ +P
Sbjct: 386 CGKLASP 392


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  143 bits (360), Expect = 2e-34
 Identities = 87/251 (34%), Positives = 142/251 (56%), Gaps = 13/251 (5%)

Query: 92  RINSHVKKKTQGKVVDIIQ--GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGE 149
           +INS VK +T+GK+ +++    +D  T MVLVN ++FK KW+ PF  +     +PF V  
Sbjct: 168 KINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNS 226

Query: 150 QVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQAL 204
                V MM+ +E+   G   +L   +L++ Y GD   F +LP +       +  LE  +
Sbjct: 227 AQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEI 286

Query: 205 SARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261
           +   L KW+    + +  +EV+IP+F +   Y L +IL  MG+++ F+K  A+FSG+++R
Sbjct: 287 TYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSER 346

Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321
           + L +S+  H+A++DV+EEGTEA A T      R+  G   F    +  FL +I +K T+
Sbjct: 347 NDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITN 404

Query: 322 GILFLGKVENP 332
            ILF G+  +P
Sbjct: 405 CILFFGRFSSP 415



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 14/30 (46%), Positives = 20/30 (66%)

Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPARINS 95
          NT FA  L++ L   +P+QN+F SP  I+S
Sbjct: 8  NTLFALNLFKHLAKASPTQNLFLSPWSISS 37


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  143 bits (360), Expect = 2e-34
 Identities = 87/251 (34%), Positives = 142/251 (56%), Gaps = 13/251 (5%)

Query: 92  RINSHVKKKTQGKVVDIIQ--GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGE 149
           +INS VK +T+GK+ +++    +D  T MVLVN ++FK KW+ PF  +     +PF V  
Sbjct: 168 KINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNS 226

Query: 150 QVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQAL 204
                V MM+ +E+   G   +L   +L++ Y GD   F +LP +       +  LE  +
Sbjct: 227 AQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEI 286

Query: 205 SARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261
           +   L KW+    + +  +EV+IP+F +   Y L +IL  MG+++ F+K  A+FSG+++R
Sbjct: 287 TYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSER 346

Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321
           + L +S+  H+A++DV+EEGTEA A T      R+  G   F    +  FL +I +K T+
Sbjct: 347 NDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITN 404

Query: 322 GILFLGKVENP 332
            ILF G+  +P
Sbjct: 405 CILFFGRFSSP 415



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 14/30 (46%), Positives = 20/30 (66%)

Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPARINS 95
          NT FA  L++ L   +P+QN+F SP  I+S
Sbjct: 8  NTLFALNLFKHLAKASPTQNLFLSPWSISS 37


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  141 bits (356), Expect = 7e-34
 Identities = 79/250 (31%), Positives = 146/250 (58%), Gaps = 13/250 (5%)

Query: 93  INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150
           IN  V+  T   V D++  +  D  T + L+N ++FK  W+  F PE TR  F F   ++
Sbjct: 151 INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFSFTKDDE 209

Query: 151 VTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK--MRQLEQ 202
             V +PMM+Q+ +F +G  ++ +        VL++ Y+GD ++  ++ S+ +  +  LE 
Sbjct: 210 SEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEP 269

Query: 203 ALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRD 262
            + A+ + +W++S++K+ +EV++PRF++    +L+ +L  +GI  +F K+A+ +G++   
Sbjct: 270 LVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNK 329

Query: 263 SLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDG 322
            + +SKA HK+ L+V+EEG+E  AA  +  I  S+    Y  V  +  F  +I N+ T  
Sbjct: 330 EIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGT 387

Query: 323 ILFLGKVENP 332
           ILF+G+V +P
Sbjct: 388 ILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  141 bits (356), Expect = 7e-34
 Identities = 79/250 (31%), Positives = 146/250 (58%), Gaps = 13/250 (5%)

Query: 93  INSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150
           IN  V+  T   V D++  +  D  T + L+N ++FK  W+  F PE TR  F F   ++
Sbjct: 151 INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFSFTKDDE 209

Query: 151 VTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK--MRQLEQ 202
             V +PMM+Q+ +F +G  ++ +        VL++ Y+GD ++  ++ S+ +  +  LE 
Sbjct: 210 SEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEP 269

Query: 203 ALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRD 262
            + A+ + +W++S++K+ +EV++PRF++    +L+ +L  +GI  +F K+A+ +G++   
Sbjct: 270 LVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNK 329

Query: 263 SLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDG 322
            + +SKA HK+ L+V+EEG+E  AA  +  I  S+    Y  V  +  F  +I N+ T  
Sbjct: 330 EIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGT 387

Query: 323 ILFLGKVENP 332
           ILF+G+V +P
Sbjct: 388 ILFMGRVMHP 397


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  140 bits (352), Expect = 2e-33
 Identities = 81/243 (33%), Positives = 132/243 (54%), Gaps = 7/243 (2%)

Query: 93  INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152
           +N ++ K+T+GK+  +   ++  T ++LV++I FK KW  PF P +T  +  F + +  T
Sbjct: 205 MNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVD-TFHLDKYKT 263

Query: 153 VHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTLRK 211
           + VPMM+   +FA   D    C VL++ Y+G+A    VL  K G    LE  L+   +  
Sbjct: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI-AKRDSLQVSKAT 270
           W  +++ R +EVF P+F +   Y +  +L +MGI+ +F   AD S + A   +LQVS+  
Sbjct: 324 WLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVL 383

Query: 271 HKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVE 330
            + V++V E GTEA A   ++    S        +  +R F  MI  + +  +LFLG+V 
Sbjct: 384 QRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYEETSGMLLFLGRVV 439

Query: 331 NPT 333
           NPT
Sbjct: 440 NPT 442


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  140 bits (352), Expect = 2e-33
 Identities = 81/243 (33%), Positives = 132/243 (54%), Gaps = 7/243 (2%)

Query: 93  INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152
           +N ++ K+T+GK+  +   ++  T ++LV++I FK KW  PF P +T  +  F + +  T
Sbjct: 205 MNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVD-TFHLDKYKT 263

Query: 153 VHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMRQLEQALSARTLRK 211
           + VPMM+   +FA   D    C VL++ Y+G+A    VL  K G    LE  L+   +  
Sbjct: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323

Query: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI-AKRDSLQVSKAT 270
           W  +++ R +EVF P+F +   Y +  +L +MGI+ +F   AD S + A   +LQVS+  
Sbjct: 324 WLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVL 383

Query: 271 HKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVE 330
            + V++V E GTEA A   ++    S        +  +R F  MI  + +  +LFLG+V 
Sbjct: 384 QRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYEETSGMLLFLGRVV 439

Query: 331 NPT 333
           NPT
Sbjct: 440 NPT 442


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  138 bits (348), Expect = 6e-33
 Identities = 91/256 (35%), Positives = 143/256 (55%), Gaps = 10/256 (3%)

Query: 84  QNIFFSPARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRK 141
           +N   S A IN  V  KT+G++ D+I  + ++ LT +VLVN I+FK  W+  F PE TRK
Sbjct: 209 ENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRK 268

Query: 142 NFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAF-FVLPSKGK-MRQ 199
              F   +  +    MM+Q+ +F +    E    VL++ +KGD +    +LP   K + +
Sbjct: 269 EL-FYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAK 326

Query: 200 LEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFD-KNADFSGI 258
           +E+ L+   L++W   L++  + V +PRF I   ++L+  L  MG+ ++F  + +   GI
Sbjct: 327 VEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGI 386

Query: 259 AK--RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMIT 316
               RD L VS A HKA L+V+EEG+EA A+T      RS + P+  T   NR FL+ I 
Sbjct: 387 VAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLN-PNRVTFKANRPFLVFIR 445

Query: 317 NKATDGILFLGKVENP 332
               + I+F+G+V NP
Sbjct: 446 EVPLNTIIFMGRVANP 461


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  137 bits (346), Expect = 1e-32
 Identities = 84/251 (33%), Positives = 143/251 (56%), Gaps = 14/251 (5%)

Query: 93  INSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQ 150
           IN  VK +T+GK+ +++    +D +T +VLVN I+FK  W+  F  E T  N PF + ++
Sbjct: 132 INQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATT-NAPFRLNKK 190

Query: 151 VTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL------PSKGKMRQLEQAL 204
               V MM+QK++FA+G   +L C VL++ Y+G+ ++  +L           ++++E+ L
Sbjct: 191 DRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQL 250

Query: 205 SARTLRKWSHSLQKRWIE--VFIPRFSISASYNLETILPKMGIQNVFDKN-ADFSGIAKR 261
           +   L +W+      +IE  V +PRF +  SY L + L ++G+Q++F+ + AD SG++  
Sbjct: 251 TLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGA 310

Query: 262 DSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATD 321
             + +SK  HK+ ++V+EEGTEA AAT              FT   +  FL  I + ++ 
Sbjct: 311 RDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--DHPFLFFIRHNSSG 368

Query: 322 GILFLGKVENP 332
            ILFLG+  +P
Sbjct: 369 SILFLGRFSSP 379



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 16/35 (45%), Positives = 20/35 (57%)

Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINS 95
          Q+ S NT FA  L+  L    P+ NIF SP  I+S
Sbjct: 3  QLSSANTRFALDLFLALSENNPAGNIFISPFSISS 37


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,962,078
Number of Sequences: 37866
Number of extensions: 507383
Number of successful extensions: 1652
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1413
Number of HSP's gapped (non-prelim): 107
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press