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Search of human proteins with 148886707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148886707 hephaestin-like 1 [Homo sapiens]
(1159 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148886707 hephaestin-like 1 [Homo sapiens] 2425 0.0
gi|195963313 hephaestin isoform a [Homo sapiens] 1209 0.0
gi|195947365 hephaestin isoform c [Homo sapiens] 1208 0.0
gi|4557485 ceruloplasmin precursor [Homo sapiens] 1117 0.0
gi|7662254 hephaestin isoform b [Homo sapiens] 894 0.0
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 471 e-132
gi|105990535 coagulation factor V precursor [Homo sapiens] 440 e-123
gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapi... 40 0.010
gi|148727264 transcription elongation regulator 1-like [Homo sap... 34 0.71
gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens] 32 2.7
>gi|148886707 hephaestin-like 1 [Homo sapiens]
Length = 1159
Score = 2425 bits (6284), Expect = 0.0
Identities = 1159/1159 (100%), Positives = 1159/1159 (100%)
Query: 1 MPRKQPAGCIFLLTFLGLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLAT 60
MPRKQPAGCIFLLTFLGLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLAT
Sbjct: 1 MPRKQPAGCIFLLTFLGLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLAT 60
Query: 61 LFLERGPNRIGSIYKKAVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFA 120
LFLERGPNRIGSIYKKAVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFA
Sbjct: 61 LFLERGPNRIGSIYKKAVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFA 120
Query: 121 SRPYSLHPHGVFYNKDSEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADAN 180
SRPYSLHPHGVFYNKDSEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADAN
Sbjct: 121 SRPYSLHPHGVFYNKDSEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADAN 180
Query: 181 CLTWVYHSHIDAPKDICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWY 240
CLTWVYHSHIDAPKDICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWY
Sbjct: 181 CLTWVYHSHIDAPKDICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWY 240
Query: 241 LNENIKHFCTNPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNE 300
LNENIKHFCTNPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNE
Sbjct: 241 LNENIKHFCTNPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNE 300
Query: 301 IDIHSIYFYGNTFISRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQ 360
IDIHSIYFYGNTFISRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQ
Sbjct: 301 IDIHSIYFYGNTFISRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQ 360
Query: 361 YNVDNCKSDIFYPKMKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQG 420
YNVDNCKSDIFYPKMKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQG
Sbjct: 361 YNVDNCKSDIFYPKMKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQG 420
Query: 421 DNRIGGKYWKVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKV 480
DNRIGGKYWKVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKV
Sbjct: 421 DNRIGGKYWKVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKV 480
Query: 481 YSILPHGVIYDKASDAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLY 540
YSILPHGVIYDKASDAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLY
Sbjct: 481 YSILPHGVIYDKASDAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLY 540
Query: 541 FSAVDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQK 600
FSAVDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQK
Sbjct: 541 FSAVDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQK 600
Query: 601 FIWHPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIV 660
FIWHPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIV
Sbjct: 601 FIWHPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIV 660
Query: 661 FQGNTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCD 720
FQGNTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCD
Sbjct: 661 FQGNTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCD 720
Query: 721 NRDPSEQRYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGS 780
NRDPSEQRYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGS
Sbjct: 721 NRDPSEQRYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGS 780
Query: 781 QYKKVVYREYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQ 840
QYKKVVYREYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQ
Sbjct: 781 QYKKVVYREYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQ 840
Query: 841 GVEEMDSGKQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGL 900
GVEEMDSGKQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGL
Sbjct: 841 GVEEMDSGKQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGL 900
Query: 901 MGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD 960
MGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD
Sbjct: 901 MGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD 960
Query: 961 FEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSY 1020
FEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSY
Sbjct: 961 FEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSY 1020
Query: 1021 REDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSP 1080
REDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSP
Sbjct: 1021 REDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSP 1080
Query: 1081 GVASHPATVPSNERPGKEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVILSLRLCSA 1140
GVASHPATVPSNERPGKEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVILSLRLCSA
Sbjct: 1081 GVASHPATVPSNERPGKEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVILSLRLCSA 1140
Query: 1141 MKQTDYQQVQSCALPTDAL 1159
MKQTDYQQVQSCALPTDAL
Sbjct: 1141 MKQTDYQQVQSCALPTDAL 1159
>gi|195963313 hephaestin isoform a [Homo sapiens]
Length = 1161
Score = 1209 bits (3127), Expect = 0.0
Identities = 575/1117 (51%), Positives = 767/1117 (68%), Gaps = 14/1117 (1%)
Query: 21 LVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYR 80
L TR YY+GI + WNY P+G+NVIT + D +A+ FL+ NRIG YKK +Y+
Sbjct: 23 LTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYK 82
Query: 81 RFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGA 140
+ D +Y+ E+ +P WLGFLGP+L+AEVGDVI+IHLKNFA+RPY++HPHGVFY KDSEG+
Sbjct: 83 EYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGS 142
Query: 141 LYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGL 200
LYPDG+SG K DD VPPG ++ Y W + E +APT AD CLTW+YHSH+DAP+DI +GL
Sbjct: 143 LYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGL 202
Query: 201 IGPLLVCKEGILNRYSGT-RNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKD 259
IGPL+ CK G L+ S R DVD +F ++F++VDEN SW+LNENI +C++P SVDK+D
Sbjct: 203 IGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKED 262
Query: 260 AVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHR 319
FQ SN+MHA+NG++FGN PE +MC + V+WHLFGMGNEID+H+ +F+G +RGH
Sbjct: 263 ETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHH 322
Query: 320 TDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQ 379
TDV N+FPATF+T EM+ PG W+I+CQV+ H + GM Y V +C + G+
Sbjct: 323 TDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKV 382
Query: 380 RRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDA 439
R+YFI A +I WDY P G++ +G L GS SD +F + +RIGG YWKVRY F D
Sbjct: 383 RQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDE 442
Query: 440 TFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPN 499
TF ++ L E+ HLGILGPVI+AEVGDT+ V F N+A + +S+ PHGV Y+K +
Sbjct: 443 TFQEKMHLE-EDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVY 501
Query: 500 LDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLL 559
DG PG KP E TY+WTVP PTA DP CLT++YFSA DPI+DT+SGLVGPLL
Sbjct: 502 NDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLL 561
Query: 560 VCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE-FVKS 618
VC+ G L ADG QKG+DKEF+LLFTV DEN S Y + N Q F + ED E F S
Sbjct: 562 VCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNAN-QAAAMLDFRLLSEDIEGFQDS 620
Query: 619 NRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLAL 678
NRMHA+NG+++ N P L+MCK D V+WHL+GLGT+TD+HG++FQGNT+ L+G + + L
Sbjct: 621 NRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAML 680
Query: 679 FPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPS-EQRYGMIRTFYI 737
FPH A MQPD+ G F ++C H GM IY VS C + QRY R +YI
Sbjct: 681 FPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYI 740
Query: 738 AAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVE 797
AEEVEWDY P+++WE E H + + +G IF++ + +GS+YKK V+REYTDG F
Sbjct: 741 MAEEVEWDYCPDRSWERE-WHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRI 799
Query: 798 IKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTK 857
+ R EEHL +LGP+I EVG+ + ++FKN ASRPYS+ A GV E + +
Sbjct: 800 PRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPL---AAE 856
Query: 858 PGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGR 917
PGEV TY+WNIP+RSGPGP+D C+ W+YYS V+ +KD YSGL+GPL C+KG+L G
Sbjct: 857 PGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGG 916
Query: 918 RSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD-FEESNRMHAINGKIFG 976
RSD+D EFALLFL+F+EN+SWYL++N+ + ++DP D+ F ESN+MHAINGK++
Sbjct: 917 RSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYA 976
Query: 977 NLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIE 1036
NL GL M + WY+L +G +VD+HTIH+HAESFL++ ++YR DV DLFPGTF+ +E
Sbjct: 977 NLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVE 1036
Query: 1037 LFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSPGVASHPATVPSNERPG 1096
+ A +PGTWL+HCHV+DH+HAGMET +TV ++ P + + + A P + G
Sbjct: 1037 MVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK--ETEKAVPPRDIEEG 1094
Query: 1097 KEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVIL 1133
++ G + + +L I + LL+ + L
Sbjct: 1095 NVKM--LGMQIPIKNVEMLASVLVAISVTLLLVVLAL 1129
>gi|195947365 hephaestin isoform c [Homo sapiens]
Length = 1160
Score = 1208 bits (3126), Expect = 0.0
Identities = 575/1117 (51%), Positives = 766/1117 (68%), Gaps = 15/1117 (1%)
Query: 21 LVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYR 80
L TR YY+GI + WNY P+G+NVIT + D +A+ FL+ NRIG YKK +Y+
Sbjct: 23 LTDGATRVYYLGIRDVQWNYAPKGRNVITNQPLDSDIVASSFLKSDKNRIGGTYKKTIYK 82
Query: 81 RFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGA 140
+ D +Y+ E+ +P WLGFLGP+L+AEVGDVI+IHLKNFA+RPY++HPHGVFY KDSEG+
Sbjct: 83 EYKDDSYTDEVAQPAWLGFLGPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGS 142
Query: 141 LYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGL 200
LYPDG+SG K DD VPPG ++ Y W + E +APT AD CLTW+YHSH+DAP+DI +GL
Sbjct: 143 LYPDGSSGPLKADDSVPPGGSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGL 202
Query: 201 IGPLLVCKEGILNRYSGT-RNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKD 259
IGPL+ CK G L+ S R DVD +F ++F++VDEN SW+LNENI +C++P SVDK+D
Sbjct: 203 IGPLITCKRGALDGNSPPQRQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKED 262
Query: 260 AVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHR 319
FQ SN+MHA+NG++FGN PE +MC + V+WHLFGMGNEID+H+ +F+G +RGH
Sbjct: 263 ETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHH 322
Query: 320 TDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQ 379
TDV N+FPATF+T EM+ PG W+I+CQV+ H + GM Y V +C + G+
Sbjct: 323 TDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKV 382
Query: 380 RRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDA 439
R+YFI A +I WDY P G++ +G L GS SD +F + +RIGG YWKVRY F D
Sbjct: 383 RQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDE 442
Query: 440 TFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPN 499
TF ++ L E+ HLGILGPVI+AEVGDT+ V F N+A + +S+ PHGV Y+K +
Sbjct: 443 TFQEKMHLE-EDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVY 501
Query: 500 LDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLL 559
DG PG KP E TY+WTVP PTA DP CLT++YFSA DPI+DT+SGLVGPLL
Sbjct: 502 NDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLL 561
Query: 560 VCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE-FVKS 618
VC+ G L ADG QKG+DKEF+LLFTV DEN S Y + N Q F + ED E F S
Sbjct: 562 VCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNAN-QAAAMLDFRLLSEDIEGFQDS 620
Query: 619 NRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLAL 678
NRMHA+NG+++ N P L+MCK D V+WHL+GLGT+TD+HG++FQGNT+ L+G + + L
Sbjct: 621 NRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAML 680
Query: 679 FPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPS-EQRYGMIRTFYI 737
FPH A MQPD+ G F ++C H GM IY VS C + QRY R +YI
Sbjct: 681 FPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYI 740
Query: 738 AAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVE 797
AEEVEWDY P+++WE E H + + +G IF++ + +GS+YKK V+REYTDG F
Sbjct: 741 MAEEVEWDYCPDRSWERE-WHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRI 799
Query: 798 IKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTK 857
+ R EEHL +LGP+I EVG+ + ++FKN ASRPYS+ A GV E + +
Sbjct: 800 PRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPL---AAE 856
Query: 858 PGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGR 917
PGEV TY+WNIP+RSGPGP+D C+ W+YYS V+ +KD YSGL+GPL C+KG+L G
Sbjct: 857 PGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGG 916
Query: 918 RSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD-FEESNRMHAINGKIFG 976
RSD+D EFALLFL+F+EN+SWYL++N+ + ++DP D+ F ESN+MHAINGK++
Sbjct: 917 RSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYA 976
Query: 977 NLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIE 1036
NL GL M + WY+L +G +VD+HTIH+HAESFL++ ++YR DV DLFPGTF+ +E
Sbjct: 977 NLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVE 1036
Query: 1037 LFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSPGVASHPATVPSNERPG 1096
+ A +PGTWL+HCHV+DH+HAGMET +TV ++ P + + P P + G
Sbjct: 1037 MVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKVP---PRDIEEG 1093
Query: 1097 KEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVIL 1133
++ G + + +L I + LL+ + L
Sbjct: 1094 NVKM--LGMQIPIKNVEMLASVLVAISVTLLLVVLAL 1128
>gi|4557485 ceruloplasmin precursor [Homo sapiens]
Length = 1065
Score = 1117 bits (2890), Expect = 0.0
Identities = 546/1054 (51%), Positives = 716/1054 (67%), Gaps = 24/1054 (2%)
Query: 29 YYIGIVEEYWNYVPQG--KNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYRRFTDGT 86
YYIGI+E W+Y K +I+ + + + ++L+ GP+RIG +YKKA+Y ++TD T
Sbjct: 24 YYIGIIETTWDYASDHGEKKLIS----VDTEHSNIYLQNGPDRIGRLYKKALYLQYTDET 79
Query: 87 YSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGT 146
+ I KP WLGFLGPI++AE GD + +HLKN ASRPY+ H HG+ Y K+ EGA+YPD T
Sbjct: 80 FRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNT 139
Query: 147 SGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGLIGPLLV 206
+ + DD V PG+ YTY+ EE +P D NC+T +YHSHIDAPKDI SGLIGPL++
Sbjct: 140 TDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLII 199
Query: 207 CKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKDAVFQRSN 266
CK+ L++ +DREFV+MF++VDEN SWYL +NIK +C+ P+ VDK + FQ SN
Sbjct: 200 CKKDSLDKEK--EKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESN 257
Query: 267 KMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLF 326
+M+++NGY FG+ P MC + V W+LFGMGNE+D+H+ +F+G ++ +R D +NLF
Sbjct: 258 RMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLF 317
Query: 327 PATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQ-RRYFIA 385
PAT M+A+NPG+WM++CQ +HL+AG+ + V C ++G+ R Y+IA
Sbjct: 318 PATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKHVRHYYIA 377
Query: 386 AEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDATFTKRK 445
AE+I+W+YAP G + F+ L A GSDS ++F QG RIGG Y K+ Y E+ DA+FT RK
Sbjct: 378 AEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRK 437
Query: 446 RLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDA---APNLDG 502
EE HLGILGPVI AEVGDT+ VTF NK SI P GV ++K ++ +PN +
Sbjct: 438 ERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNP 497
Query: 503 ---FVKPGA-HVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPL 558
V P A HV P ETFTY+WTVP+ V PT DP CL +Y+SAVDP KD +GL+GP+
Sbjct: 498 QSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGPM 557
Query: 559 LVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKEFVKS 618
+CKKG L+A+G QK +DKEFYL TVFDEN S ++NI+ F P +DKED++F +S
Sbjct: 558 KICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQES 617
Query: 619 NRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLAL 678
N+MH++NG+MYGNQPGL MCK D V W+L G + D+HGI F GNT RG RD+ L
Sbjct: 618 NKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTANL 677
Query: 679 FPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPSEQRYGMIRTFYIA 738
FP + T M PD G F V C T H + GM Q Y V+ C + Y RT+YIA
Sbjct: 678 FPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDSTFYLGERTYYIA 737
Query: 739 AEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVEI 798
A EVEWDY+P + WE E H+ + + + F+++ E +IGS+YKKVVYR+YTD F
Sbjct: 738 AVEVEWDYSPQREWEKELHHL--QEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVP 795
Query: 799 KARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTKP 858
R EEHL +LGP +HA+VG+ V IIFKN A+RPYSI A GV+ S V T P
Sbjct: 796 VERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESS----TVTPTLP 851
Query: 859 GEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGRR 918
GE TY W IP+RSG G D CIPW YYSTV+ VKD YSGL+GPLI CR+ L R
Sbjct: 852 GETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFNPR 911
Query: 919 SDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDDFEESNRMHAINGKIFGNL 978
+ EFALLFLVF+ENESWYLDDNIK Y + + K ++F ESN+MHAING++FGNL
Sbjct: 912 RKL--EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNL 969
Query: 979 HGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELF 1038
GL M+ NWYL+G+G+E+D+HT+H+H SF +K Y DV+D+FPGT+QT+E+F
Sbjct: 970 QGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMF 1029
Query: 1039 ADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNR 1072
PG WLLHCHV+DHIHAGMETTYTVL+N D +
Sbjct: 1030 PRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTK 1063
Score = 529 bits (1362), Expect = e-150
Identities = 287/705 (40%), Positives = 408/705 (57%), Gaps = 27/705 (3%)
Query: 23 GTVTRTYYIGIVEEYWNYVPQGKNVITGKSFT-EDKLATLFLERGPNRIGSIYKKAVYRR 81
G R YYI E WNY P G ++ T ++ T + +F E+G RIG YKK VYR
Sbjct: 368 GKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYRE 427
Query: 82 FTDGTYSIEI---PKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSE 138
+TD +++ P+ LG LGP++ AEVGD I + N + P S+ P GV +NK++E
Sbjct: 428 YTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNE 487
Query: 139 GALYPDGTSGRNK----NDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPK 194
G Y + +++ + V P + +TY W V +E PT AD CL +Y+S +D K
Sbjct: 488 GTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTK 547
Query: 195 DICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDS 254
DI +GLIGP+ +CK+G L+ +G + DVD+EF + T+ DEN+S L +NI+ F T PD
Sbjct: 548 DIFTGLIGPMKICKKGSLHA-NGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQ 606
Query: 255 VDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFI 314
VDK+D FQ SNKMH++NG+++GN P MC G+SV W+LF GNE D+H IYF GNT++
Sbjct: 607 VDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYL 666
Query: 315 SRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPK 374
RG R D NLFP T LT M + G + + C +DH GM +Y V+ C+
Sbjct: 667 WRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDST 726
Query: 375 MKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYT 434
+R Y+IAA ++ WDY+PQ + L + S+ + +G+ IG KY KV Y
Sbjct: 727 FYLGERTYYIAAVEVEWDYSPQREWE-KELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYR 785
Query: 435 EFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKAS 494
++ D+TF AEE HLGILGP + A+VGD + + F N A + YSI HGV ++S
Sbjct: 786 QYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGV-QTESS 844
Query: 495 DAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGL 554
P L PGET TY W +PE D C+ + Y+S VD +KD SGL
Sbjct: 845 TVTPTL-----------PGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGL 893
Query: 555 VGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE 614
+GPL+VC++ L ++ + EF LLF VFDEN S Y D+NI+ + HP ++K+D+E
Sbjct: 894 IGPLIVCRRPYLKVFNPRRKL--EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEE 951
Query: 615 FVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHL--RGTH 672
F++SN+MHA+NG M+GN GL M D V+W+L+G+G + D+H + F G++ RG +
Sbjct: 952 FIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVY 1011
Query: 673 -RDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEV 716
D +FP T M P GI+ + C H+ GM Y V
Sbjct: 1012 SSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTV 1056
Score = 499 bits (1285), Expect = e-141
Identities = 269/708 (37%), Positives = 400/708 (56%), Gaps = 32/708 (4%)
Query: 378 QQRRYFIAAEKILWDYA-PQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEF 436
+++ Y+I + WDYA G K ++ S++Y G +RIG Y K Y ++
Sbjct: 20 KEKHYYIGIIETTWDYASDHGEKKL----ISVDTEHSNIYLQNGPDRIGRLYKKALYLQY 75
Query: 437 VDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDA 496
D TF + + LG LGP+IKAE GD + V N A + Y+ HG+ Y K +
Sbjct: 76 TDETF---RTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEG 132
Query: 497 A---PNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSG 553
A N F + V PGE +TY E SP GD C+T +Y S +D KD +SG
Sbjct: 133 AIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASG 192
Query: 554 LVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDK 613
L+GPL++CKK L+ + +K ID+EF ++F+V DEN S Y ++NI+ + P +DK+++
Sbjct: 193 LIGPLIICKKDSLDKE-KEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNE 251
Query: 614 EFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHR 673
+F +SNRM++VNGY +G+ PGL+MC DRV W+L G+G + D+H F G + +
Sbjct: 252 DFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRI 311
Query: 674 DSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPSEQRYGM-I 732
D++ LFP A+M + G + + C + HL G+ ++V C+ + G +
Sbjct: 312 DTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKHV 371
Query: 733 RTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTD 792
R +YIAAEE+ W+YAP+ F K+++ A G +F + IG YKK+VYREYTD
Sbjct: 372 RHYYIAAEEIIWNYAPSGIDIFTKENLTAPGS-DSAVFFEQGTTRIGGSYKKLVYREYTD 430
Query: 793 GEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGV--EEMDSGKQ 850
F K R P EEHL +LGP+I AEVG+T+ + F NK + P SI GV + + G
Sbjct: 431 ASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTY 490
Query: 851 F---------QVPMT----KPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTY 897
+ VP + P E TY W +PK GP +DP C+ +YYS V+ KD +
Sbjct: 491 YSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIF 550
Query: 898 SGLMGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKR 957
+GL+GP+ C+KG L+ GR+ DVD EF L VF+ENES L+DNI+ + + K
Sbjct: 551 TGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKE 610
Query: 958 TDDFEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKID 1017
+DF+ESN+MH++NG ++GN GL M + WYL G+E D+H I++ ++L+
Sbjct: 611 DEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLW--- 667
Query: 1018 KSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTV 1065
+ R D +LFP T T+ ++ D GT+ + C +DH GM+ YTV
Sbjct: 668 RGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTV 715
>gi|7662254 hephaestin isoform b [Homo sapiens]
Length = 891
Score = 894 bits (2311), Expect = 0.0
Identities = 432/869 (49%), Positives = 580/869 (66%), Gaps = 13/869 (1%)
Query: 268 MHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLFP 327
MHA+NG++FGN PE +MC + V+WHLFGMGNEID+H+ +F+G +RGH TDV N+FP
Sbjct: 1 MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP 60
Query: 328 ATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQRRYFIAAE 387
ATF+T EM+ PG W+I+CQV+ H + GM Y V +C + G+ R+YFI A
Sbjct: 61 ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH 120
Query: 388 KILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDATFTKRKRL 447
+I WDY P G++ +G L GS SD +F + +RIGG YWKVRY F D TF ++ L
Sbjct: 121 EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL 180
Query: 448 SAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNLDGFVKPG 507
E+ HLGILGPVI+AEVGDT+ V F N+A + +S+ PHGV Y+K + DG PG
Sbjct: 181 E-EDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPG 239
Query: 508 AHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLLVCKKGVLN 567
KP E TY+WTVP PTA DP CLT++YFSA DPI+DT+SGLVGPLLVC+ G L
Sbjct: 240 LVAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALG 299
Query: 568 ADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE-FVKSNRMHAVNG 626
ADG QKG+DKEF+LLFTV DEN S Y + N Q F + ED E F SNRMHA+NG
Sbjct: 300 ADGKQKGVDKEFFLLFTVLDENKSWYSNAN-QAAAMLDFRLLSEDIEGFQDSNRMHAING 358
Query: 627 YMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLALFPHMATTA 686
+++ N P L+MCK D V+WHL+GLGT+TD+HG++FQGNT+ L+G + + LFPH A
Sbjct: 359 FLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMA 418
Query: 687 FMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPS-EQRYGMIRTFYIAAEEVEWD 745
MQPD+ G F ++C H GM IY VS C + QRY R +YI AEEVEWD
Sbjct: 419 IMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWD 478
Query: 746 YAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVEIKARPPRE 805
Y P+++WE E H + + +G IF++ + +GS+YKK V+REYTDG F + R E
Sbjct: 479 YCPDRSWERE-WHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPE 537
Query: 806 EHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTKPGEVKTYR 865
EHL +LGP+I EVG+ + ++FKN ASRPYS+ A GV E + +PGEV TY+
Sbjct: 538 EHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPL---AAEPGEVVTYQ 594
Query: 866 WNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGRRSDVDYEF 925
WNIP+RSGPGP+D C+ W+YYS V+ +KD YSGL+GPL C+KG+L G RSD+D EF
Sbjct: 595 WNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREF 654
Query: 926 ALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD-FEESNRMHAINGKIFGNLHGLIMN 984
ALLFL+F+EN+SWYL++N+ + ++DP D+ F ESN+MHAINGK++ NL GL M
Sbjct: 655 ALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMY 714
Query: 985 EDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHPGT 1044
+ WY+L +G +VD+HTIH+HAESFL++ ++YR DV DLFPGTF+ +E+ A +PGT
Sbjct: 715 QGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGT 774
Query: 1045 WLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSPGVASHPATVPSNERPGKEQLYFFG 1104
WL+HCHV+DH+HAGMET +TV ++ P + + + A P + G ++ G
Sbjct: 775 WLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK--ETEKAVPPRDIEEGNVKM--LG 830
Query: 1105 KNLGPTGAKAALVILFIIGLLLLITTVIL 1133
+ + +L I + LL+ + L
Sbjct: 831 MQIPIKNVEMLASVLVAISVTLLLVVLAL 859
Score = 511 bits (1317), Expect = e-144
Identities = 281/706 (39%), Positives = 393/706 (55%), Gaps = 24/706 (3%)
Query: 21 LVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTED-KLATLFLERGPNRIGSIYKKAVY 79
L G V R Y+I E W+Y P G + TGK+ E ++ F ++ +RIG Y K Y
Sbjct: 108 LTGKV-RQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRY 166
Query: 80 RRFTDGTYS--IEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDS 137
F D T+ + + + LG LGP++RAEVGD I + N AS+P+S+ PHGVFY KD
Sbjct: 167 EAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDY 226
Query: 138 EGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDIC 197
EG +Y DG+S + P + TY W V PT D CLTW+Y S D +D
Sbjct: 227 EGTVYNDGSSYPGL---VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTN 283
Query: 198 SGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDK 257
SGL+GPLLVC+ G L G + VD+EF ++FT++DEN+SWY N N + + +
Sbjct: 284 SGLVGPLLVCRAGALGA-DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSE 342
Query: 258 KDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRG 317
FQ SN+MHA+NG+LF N P DMC G++V+WHL G+G E D+H + F GNT +G
Sbjct: 343 DIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQG 402
Query: 318 HRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKG 377
R LFP TF+ M +N G + I CQ H +AGM YNV C P+ +
Sbjct: 403 MRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRY 462
Query: 378 QQRR-YFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEF 436
Q R Y+I AE++ WDY P + + S ++ + D +G +Y K + E+
Sbjct: 463 QAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREY 522
Query: 437 VDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDA 496
D TF + + E HLGILGP+IK EVGD L V F N A + YS+ HGV+
Sbjct: 523 TDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTT--- 579
Query: 497 APNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVG 556
V P A +PGE TY+W +PE P D C++++Y+SAVDPIKD SGLVG
Sbjct: 580 -------VWPLA-AEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLVG 631
Query: 557 PLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKF-IWHPFSIDKEDKEF 615
PL +C+KG+L G + +D+EF LLF +FDEN S Y +EN+ P SI+ +D+ F
Sbjct: 632 PLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDETF 691
Query: 616 VKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHR-- 673
++SN+MHA+NG +Y N GL M + +RV+W+++ +G D D+H I F + R
Sbjct: 692 LESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENYR 751
Query: 674 -DSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSS 718
D + LFP M + G + + C H+ GM ++ V S
Sbjct: 752 ADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFS 797
>gi|4503647 coagulation factor VIII isoform a precursor [Homo
sapiens]
Length = 2351
Score = 471 bits (1212), Expect = e-132
Identities = 282/775 (36%), Positives = 403/775 (52%), Gaps = 84/775 (10%)
Query: 15 FLGLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIY 74
FL L + TR YY+G VE W+Y+ + + ++ F P +Y
Sbjct: 10 FLCLLRFCFSATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSF----PFNTSVVY 65
Query: 75 KKAVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYN 134
KK ++ FTD ++I P+PPW+G LGP ++AEV D +VI LKN AS P SLH GV Y
Sbjct: 66 KKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYW 125
Query: 135 KDSEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPK 194
K SEGA Y D TS R K DD V PG ++TYVW V +E P +D CLT+ Y SH+D K
Sbjct: 126 KASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVK 185
Query: 195 DICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDS 254
D+ SGLIG LLVC+EG L + + +F+++F + DE +SW H T
Sbjct: 186 DLNSGLIGALLVCREGSLAK---EKTQTLHKFILLFAVFDEGKSW-------HSETKNSL 235
Query: 255 VDKKDAVFQRS-NKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTF 313
+ +DA R+ KMH +NGY+ + P C +SV WH+ GMG ++HSI+ G+TF
Sbjct: 236 MQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTF 295
Query: 314 ISRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYP 373
+ R HR + + P TFLT + + + G++++ C +S H GM VD+C + P
Sbjct: 296 LVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEE---P 352
Query: 374 KMKGQQRR------------------------------------------YFIAAEKILW 391
+++ + ++IAAE+ W
Sbjct: 353 QLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDW 412
Query: 392 DYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDATFTKRKRLSAEE 451
DYAP + S Y G RIG KY KVR+ + D TF R+ + E
Sbjct: 413 DYAPL-------VLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHES 465
Query: 452 AHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNLDGFVKPGA-HV 510
GILGP++ EVGDTLL+ F N+A + Y+I PHG+ +D P + G H+
Sbjct: 466 ---GILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGI-----TDVRPLYSRRLPKGVKHL 517
Query: 511 K-----PGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLLVCKKGV 565
K PGE F YKWTV PT DP CLT Y S V+ +D +SGL+GPLL+C K
Sbjct: 518 KDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKES 577
Query: 566 LNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKEFVKSNRMHAVN 625
++ G Q DK +LF+VFDEN S Y ENIQ+F+ +P + ED EF SN MH++N
Sbjct: 578 VDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSIN 637
Query: 626 GYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLALFPHMATT 685
GY++ + L++C + W+++ +G TD + F G T + + D+L LFP T
Sbjct: 638 GYVFDSLQ-LSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGET 696
Query: 686 AFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNR--DPSEQRYGMIRTFYIA 738
FM ++ G++ + C +RGM + +VSSCD D E Y I + ++
Sbjct: 697 VFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLS 751
Score = 360 bits (925), Expect = 3e-99
Identities = 248/737 (33%), Positives = 361/737 (48%), Gaps = 94/737 (12%)
Query: 380 RRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDA 439
RRY++ A ++ WDY + LP++A + + Y K + EF D
Sbjct: 22 RRYYLGAVELSWDYMQSDLGE---LPVDARFPPRVPKSFPFNTSV--VYKKTLFVEFTDH 76
Query: 440 TFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPN 499
F K +G+LGP I+AEV DT+++T N A S+ GV Y KAS+ A
Sbjct: 77 LFNIAK---PRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEY 133
Query: 500 LDGFV---KPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVG 556
D K V PG + TY W V + P A DP CLTY Y S VD +KD +SGL+G
Sbjct: 134 DDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIG 193
Query: 557 PLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDK--EDKE 614
LLVC++G L + TQ +F LLF VFDE S WH + + +D++
Sbjct: 194 ALLVCREGSLAKEKTQTL--HKFILLFAVFDEGKS-----------WHSETKNSLMQDRD 240
Query: 615 FVKSN---RMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGT 671
+ +MH VNGY+ + PGL C R V WH+IG+GT ++H I +G+T +R
Sbjct: 241 AASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNH 300
Query: 672 HRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSC------------ 719
+ SL + P TA G F +FC H GM +V SC
Sbjct: 301 RQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNE 360
Query: 720 --------------------DNRDPS-------EQRYGMIRTFYIAAEEVEWDYAPNKNW 752
D+ PS +++ YIAAEE +WDYAP
Sbjct: 361 EAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPL--- 417
Query: 753 EFEKQHVDARGER-HGDIFMNRTENWIGSQYKKVVYREYTDGEFVEIKARPPREEHLELL 811
V A +R + ++N IG +YKKV + YTD F K R + +L
Sbjct: 418 ------VLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETF---KTREAIQHESGIL 468
Query: 812 GPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPM---------TKPGEVK 862
GP+++ EVG+T+LIIFKN+ASRPY+I G+ ++ ++P PGE+
Sbjct: 469 GPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIF 528
Query: 863 TYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGRRSDVD 922
Y+W + GP SDP C+ Y S VN +D SGL+GPL+ C K ++++G + D
Sbjct: 529 KYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSD 588
Query: 923 YEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDDFEESNRMHAINGKIFGNLHGLI 982
+LF VF+EN SWYL +NI+++L +F+ SN MH+ING +F +L L
Sbjct: 589 KRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQ-LS 647
Query: 983 MNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHP 1042
+ + WY+L IG++ D ++ + +F K+ ED LFP + +T+ + ++P
Sbjct: 648 VCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKM---VYEDTLTLFPFSGETVFMSMENP 704
Query: 1043 GTWLLHCHVSDHIHAGM 1059
G W+L CH SD + GM
Sbjct: 705 GLWILGCHNSDFRNRGM 721
Score = 242 bits (618), Expect = 1e-63
Identities = 122/339 (35%), Positives = 182/339 (53%), Gaps = 18/339 (5%)
Query: 733 RTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTD 792
R ++IAA E WDY + + + NR ++ Q+KKVV++E+TD
Sbjct: 1715 RHYFIAAVERLWDYGMSSS---------------PHVLRNRAQSGSVPQFKKVVFQEFTD 1759
Query: 793 GEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGV---EEMDSGK 849
G F + R EHL LLGP I AEV + +++ F+N+ASRPYS + + E+ G
Sbjct: 1760 GSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQGA 1819
Query: 850 QFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRK 909
+ + KP E KTY W + P + +C W Y+S V+ KD +SGL+GPL+ C
Sbjct: 1820 EPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHT 1879
Query: 910 GVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDDFEESNRMHA 969
LN R EFAL F +F+E +SWY +N+++ F+E+ R HA
Sbjct: 1880 NTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRFHA 1939
Query: 970 INGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFP 1029
ING I L GL+M +D WYLL +GS +IH+IH+ F + + Y+ +Y+L+P
Sbjct: 1940 INGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMALYNLYP 1999
Query: 1030 GTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRN 1068
G F+T+E+ G W + C + +H+HAGM T + V N
Sbjct: 2000 GVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSN 2038
Score = 219 bits (559), Expect = 9e-57
Identities = 129/379 (34%), Positives = 191/379 (50%), Gaps = 32/379 (8%)
Query: 26 TRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSI--YKKAVYRRFT 83
TR Y+I VE W+Y G S + L R + GS+ +KK V++ FT
Sbjct: 1714 TRHYFIAAVERLWDY---------GMSSSPHVL------RNRAQSGSVPQFKKVVFQEFT 1758
Query: 84 DGTYSIEIPKPPW---LGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGA 140
DG+++ + + LG LGP +RAEV D I++ +N ASRPYS + + Y +D
Sbjct: 1759 DGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQR-- 1816
Query: 141 LYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGL 200
G + V P + TY W V+ APT + +C W Y S +D KD+ SGL
Sbjct: 1817 ------QGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGL 1870
Query: 201 IGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKDA 260
IGPLLVC LN G + V +EF + FT+ DE +SWY EN++ C P ++ +D
Sbjct: 1871 IGPLLVCHTNTLNPAHGRQVTV-QEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDP 1929
Query: 261 VFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISR---G 317
F+ + + HA+NGY+ P M + + W+L MG+ +IHSI+F G+ F R
Sbjct: 1930 TFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEE 1989
Query: 318 HRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKG 377
++ + NL+P F T EM+ G W + C + +HL AGM + V + K G
Sbjct: 1990 YKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASG 2049
Query: 378 QQRRYFIAAEKILWDYAPQ 396
R + I A +AP+
Sbjct: 2050 HIRDFQITASGQYGQWAPK 2068
Score = 217 bits (553), Expect = 5e-56
Identities = 142/393 (36%), Positives = 198/393 (50%), Gaps = 29/393 (7%)
Query: 361 YNVDNCKSDIFYPKMKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQG 420
Y+ D +S + K + R YFIAA + LWDY G + + N + S S F
Sbjct: 1699 YDEDENQSPRSFQK---KTRHYFIAAVERLWDY---GMSSSPHVLRNRAQSGSVPQFK-- 1750
Query: 421 DNRIGGKYWKVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKV 480
KV + EF D +FT+ HLG+LGP I+AEV D ++VTF N+A +
Sbjct: 1751 ---------KVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRP 1801
Query: 481 YSILPHGVIY--DKASDAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTY 538
YS + Y D+ A P + VKP ET TY W V ++PT + C +
Sbjct: 1802 YSFYSSLISYEEDQRQGAEPRKN-------FVKPNETKTYFWKVQHHMAPTKDEFDCKAW 1854
Query: 539 LYFSAVDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENI 598
YFS VD KD SGL+GPLLVC LN ++ +EF L FT+FDE S YF EN+
Sbjct: 1855 AYFSDVDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENM 1914
Query: 599 QKFIWHPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHG 658
++ P +I ED F ++ R HA+NGY+ PGL M + R+ W+L+ +G++ ++H
Sbjct: 1915 ERNCRAPCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHS 1974
Query: 659 IVFQGNTIHLRGTHRDSLA---LFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYE 715
I F G+ +R +A L+P + T M P AGI+RV C HL GM ++
Sbjct: 1975 IHFSGHVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFL 2034
Query: 716 VSSCDNRDPSEQRYGMIRTFYIAAEEVEWDYAP 748
V S + P G IR F I A +AP
Sbjct: 2035 VYSNKCQTPLGMASGHIRDFQITASGQYGQWAP 2067
Score = 172 bits (436), Expect = 2e-42
Identities = 115/344 (33%), Positives = 175/344 (50%), Gaps = 33/344 (9%)
Query: 729 YGMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDAR-GERHGDIFMNRTENWIGSQYKKVVY 787
+ R +Y+ A E+ WDY + E VDAR R F T YKK ++
Sbjct: 18 FSATRRYYLGAVELSWDYMQSDLGELP---VDARFPPRVPKSFPFNTS----VVYKKTLF 70
Query: 788 REYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGV----- 842
E+TD F K RPP + LLGP I AEV +TV+I KN AS P S+ A GV
Sbjct: 71 VEFTDHLFNIAKPRPP---WMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKA 127
Query: 843 ------EEMDSGKQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDT 896
++ S ++ + PG TY W + K +GP SDP C+ + Y S V+ VKD
Sbjct: 128 SEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDL 187
Query: 897 YSGLMGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFK 956
SGL+G L+ CR+G L ++ ++ ++F LLF VF+E +SW+ + ++D +
Sbjct: 188 NSGLIGALLVCREGSLAKE--KTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASAR 245
Query: 957 RTDDFEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKI 1016
+MH +NG + +L GLI W+++G+G+ ++H+I +FL
Sbjct: 246 AWP------KMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLV-- 297
Query: 1017 DKSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGME 1060
+++R+ ++ P TF T + G +LL CH+S H H GME
Sbjct: 298 -RNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGME 340
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 440 bits (1132), Expect = e-123
Identities = 284/864 (32%), Positives = 415/864 (48%), Gaps = 97/864 (11%)
Query: 17 GLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKK 76
G G R +Y+ W+Y P+ N S T +KK
Sbjct: 22 GSQGTEAAQLRQFYVAAQGISWSYRPEPTNSSLNLSVTS------------------FKK 63
Query: 77 AVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKD 136
VYR + + + E P+ G LGP L AEVGD+I +H KN A +P S+HP G+ Y+K
Sbjct: 64 IVYREY-EPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKL 122
Query: 137 SEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDI 196
SEGA Y D T K DD V PG+ YTY W + E+ PT D CLT +Y+SH + +D
Sbjct: 123 SEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDF 182
Query: 197 CSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVD 256
SGLIGPLL+CK+G L GT+ D++ V++F + DE++SW
Sbjct: 183 NSGLIGPLLICKKGTLTE-GGTQKTFDKQIVLLFAVFDESKSWS---------------- 225
Query: 257 KKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISR 316
Q S+ M+ +NGY+ G P+ +C + +SWHL GM + ++ SI+F G
Sbjct: 226 ------QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQN 279
Query: 317 GHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNC-KSDIFYPKM 375
H+ + L AT T M GKW+I+ HLQAGM ++ NC K K+
Sbjct: 280 HHKVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKI 339
Query: 376 KGQQRR------YFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYW 429
+QRR YFIAAE+++WDYAP +P N + N+IG Y
Sbjct: 340 TREQRRHMKRWEYFIAAEEVIWDYAPV-------IPANMDKKYRSQHLDNFSNQIGKHYK 392
Query: 430 KVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVI 489
KV YT++ D +FTK ++ GILGP+I+A+V DTL + F N A + YSI PHGV
Sbjct: 393 KVMYTQYEDESFTKHT-VNPNMKEDGILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVT 451
Query: 490 YDKASDAAPNLDGFVKPGAH------VKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSA 543
+ D ++ G + V+PGET+TYKW + E PT D CLT Y+S
Sbjct: 452 FSPYED---EVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSD 508
Query: 544 VDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIW 603
VD ++D +SGL+G LL+CK L+ G Q+ D E +F VFDEN S Y ++NI KF
Sbjct: 509 VDIMRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCE 568
Query: 604 HPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQG 663
+P + ++D +F +SN M +NGY+ + L C D V WH +GT ++ I F G
Sbjct: 569 NPDEVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTG 628
Query: 664 NTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSC---D 720
++ H D+L LFP + + D+ G + + S+ + + C D
Sbjct: 629 HSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSKKLRLKFRDVKCIPDD 688
Query: 721 NRD------PSEQRYGMIRTFYIAAE------EVEWDYA--------------PNKNWEF 754
+ D P E R + E + ++DY + N E
Sbjct: 689 DEDSYEIFEPPESTVMATRKMHDRLEPEDEESDADYDYQNRLAAALGIRSFRNSSLNQEE 748
Query: 755 EKQHVDARGERHGDIFM-NRTENWIGSQYKKVV-YREYTDGEFVEIKARPPREEHLELLG 812
E+ ++ A +G F+ + T+ +GS Y ++T E + P ++
Sbjct: 749 EEFNLTALALENGTEFVSSNTDIIVGSNYSSPSNISKFTVNNLAEPQKAPSHQQATTAGS 808
Query: 813 PMIHAEVGNTVLIIFKNKASRPYS 836
P+ H N+VL + S PYS
Sbjct: 809 PLRHLIGKNSVLNSSTAEHSSPYS 832
Score = 393 bits (1009), Expect = e-109
Identities = 246/696 (35%), Positives = 358/696 (51%), Gaps = 88/696 (12%)
Query: 378 QQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFV 437
Q R++++AA+ I W Y P+ N L + + + K+ Y E+
Sbjct: 30 QLRQFYVAAQGISWSYRPEPTNSSLNLSVTS-------------------FKKIVYREY- 69
Query: 438 DATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAA 497
+ F K K S G+LGP + AEVGD + V F NKADK SI P G+ Y K S+ A
Sbjct: 70 EPYFKKEKPQSTIS---GLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGA 126
Query: 498 PNLDGFV---KPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGL 554
LD K V PG +TY+W++ E PT DPPCLT++Y+S + I+D +SGL
Sbjct: 127 SYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGL 186
Query: 555 VGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKE 614
+GPLL+CKKG L GTQK DK+ LLF VFDE+ S W
Sbjct: 187 IGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKS-----------WSQ--------- 226
Query: 615 FVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRD 674
S+ M+ VNGY+ G P + +C D +SWHL+G+ + ++ I F G +
Sbjct: 227 --SSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKVS 284
Query: 675 SLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPS------EQR 728
++ L +TTA M G + + T HL GM ++ +C + + EQR
Sbjct: 285 AITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITREQR 344
Query: 729 YGMIR-TFYIAAEEVEWDYAP----NKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYK 783
M R ++IAAEEV WDYAP N + ++ QH+D N IG YK
Sbjct: 345 RHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQHLD------------NFSNQIGKHYK 392
Query: 784 KVVYREYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGV- 842
KV+Y +Y D F + P +E +LGP+I A+V +T+ I+FKN ASRPYSI GV
Sbjct: 393 KVMYTQYEDESFTKHTVNPNMKED-GILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVT 451
Query: 843 -----EEMDSG-----KQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNF 892
+E++S + +PGE TY+WNI + P +D C+ YYS V+
Sbjct: 452 FSPYEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDI 511
Query: 893 VKDTYSGLMGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDP 952
++D SGL+G L+ C+ L+ +G + D E +F VF+EN+SWYL+DNI K+ ++P
Sbjct: 512 MRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFC-ENP 570
Query: 953 RDFKRTD-DFEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAES 1011
+ KR D F ESN M ING + ++ L D W+ +G++ +I TIH+ S
Sbjct: 571 DEVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHS 630
Query: 1012 FLFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLL 1047
F++ ED LFP +++ + D+ GTW+L
Sbjct: 631 FIY---GKRHEDTLTLFPMRGESVTVTMDNVGTWML 663
Score = 231 bits (588), Expect = 4e-60
Identities = 140/367 (38%), Positives = 203/367 (55%), Gaps = 36/367 (9%)
Query: 730 GMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYRE 789
G R +YIAAEE+ WDY+ EF ++ D E DI + T YKKVV+R+
Sbjct: 1577 GNRRNYYIAAEEISWDYS-----EFVQRETDI--EDSDDIPEDTT-------YKKVVFRK 1622
Query: 790 YTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGV--EEMDS 847
Y D F + R EEHL +LGP+I AEV + + + FKN ASRPYS+ A G+ E+
Sbjct: 1623 YLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSE 1682
Query: 848 GKQFQVPM---------TKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYS 898
GK ++ +P TY W+ +RSGP C W YYS VN KD +S
Sbjct: 1683 GKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHS 1742
Query: 899 GLMGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRT 958
GL+GPL+ C+KG+L++ EF LLF+ F+E +SWY Y K ++ T
Sbjct: 1743 GLIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWY-------YEKKSRSSWRLT 1795
Query: 959 -DDFEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKID 1017
+ ++S+ HAING I+ +L GL M E +LL IG DIH +H+H ++ L +
Sbjct: 1796 SSEMKKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGN 1854
Query: 1018 KSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYST 1077
K ++ V+ L PG+F+T+E+ A PG WLL+ V ++ AGM+T + ++ + D R+P
Sbjct: 1855 KQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIM-DRDCRMPMG- 1912
Query: 1078 TSPGVAS 1084
S G+ S
Sbjct: 1913 LSTGIIS 1919
Score = 224 bits (571), Expect = 4e-58
Identities = 130/340 (38%), Positives = 182/340 (53%), Gaps = 32/340 (9%)
Query: 27 RTYYIGIVEEYWNY---VPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYRRFT 83
R YYI E W+Y V + ++ ED + YKK V+R++
Sbjct: 1580 RNYYIAAEEISWDYSEFVQRETDIEDSDDIPED---------------TTYKKVVFRKYL 1624
Query: 84 DGTYSIEIPKPPW---LGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGA 140
D T++ P+ + LG LGPI+RAEV DVI + KN ASRPYSLH HG+ Y K SEG
Sbjct: 1625 DSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGK 1684
Query: 141 LYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGL 200
Y D + K D+ V P +YTYVW E P + C W Y+S ++ KDI SGL
Sbjct: 1685 TYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGL 1744
Query: 201 IGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKDA 260
IGPLL+C++GIL++ S D+ REFV++F DE +SWY + + S KK
Sbjct: 1745 IGPLLICQKGILHKDSNMPMDM-REFVLLFMTFDEKKSWYYEKKSRSSWRLTSSEMKK-- 1801
Query: 261 VFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRG--- 317
S++ HA+NG ++ + P M E V HL +G DIH ++F+G T + G
Sbjct: 1802 ----SHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQ 1856
Query: 318 HRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGM 357
H+ V L P +F T EM A PG W++ +V ++ +AGM
Sbjct: 1857 HQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGM 1896
Score = 193 bits (491), Expect = 7e-49
Identities = 126/371 (33%), Positives = 187/371 (50%), Gaps = 26/371 (7%)
Query: 377 GQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEF 436
G +R Y+IAAE+I WDY+ +F + SD D Y KV + ++
Sbjct: 1577 GNRRNYYIAAEEISWDYS-----EFVQRETDIEDSD--------DIPEDTTYKKVVFRKY 1623
Query: 437 VDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDA 496
+D+TFTKR E HLGILGP+I+AEV D + V F N A + YS+ HG+ Y+K+S+
Sbjct: 1624 LDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEG 1683
Query: 497 APNLDG---FVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSG 553
D + K V+P ++TY W E P + C + Y+SAV+P KD SG
Sbjct: 1684 KTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSG 1743
Query: 554 LVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDK 613
L+GPLL+C+KG+L+ D +EF LLF FDE S Y+++ + W S
Sbjct: 1744 LIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEKK-SRSSWRLTS-----S 1797
Query: 614 EFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHR 673
E KS+ HA+NG +Y + PGL M +++ V HL+ +G D+H + F G T+ G +
Sbjct: 1798 EMKKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQ 1856
Query: 674 DSLALFPHMA---TTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPSEQRYG 730
L ++P + T M+ G + + + GM + + D R P G
Sbjct: 1857 HQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTG 1916
Query: 731 MIRTFYIAAEE 741
+I I A E
Sbjct: 1917 IISDSQIKASE 1927
Score = 161 bits (407), Expect = 4e-39
Identities = 101/348 (29%), Positives = 160/348 (45%), Gaps = 61/348 (17%)
Query: 732 IRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYT 791
+R FY+AA+ + W Y P N + N + +KK+VYREY
Sbjct: 31 LRQFYVAAQGISWSYRPEPT--------------------NSSLNLSVTSFKKIVYREYE 70
Query: 792 DGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVE--EMDSGK 849
K P+ LLGP ++AEVG+ + + FKNKA +P SI QG+ ++ G
Sbjct: 71 P----YFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGA 126
Query: 850 QF---QVPMTK------PGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGL 900
+ P K PG TY W+I + SGP DP C+ +YYS N ++D SGL
Sbjct: 127 SYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGL 186
Query: 901 MGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDD 960
+GPL+ C+KG L E G + D + LLF VF+E++SW
Sbjct: 187 IGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWS--------------------- 225
Query: 961 FEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSY 1020
+ S+ M+ +NG + G + + + +W+LLG+ S ++ +IH++ + +
Sbjct: 226 -QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLE---QNHH 281
Query: 1021 REDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRN 1068
+ L T T + G W++ H+ AGM+ Y ++N
Sbjct: 282 KVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQ-AYIDIKN 328
>gi|32481206 lactase-phlorizin hydrolase preproprotein [Homo sapiens]
Length = 1927
Score = 40.4 bits (93), Expect = 0.010
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Query: 1071 NRIPYSTTSPGVASH-PATVPSNERPGKEQLYFFGKNLGPTGAKAALVILFIIGLLLLIT 1129
N P T P H P P+ +E++ F G LG T A+ AL +LF + LL +
Sbjct: 1838 NGFPDPATGPHACLHQPDAGPTISPVRQEEVQFLGLMLGTTEAQTALYVLFSLVLLGVCG 1897
Query: 1130 TVILSLRLCSAMKQTDYQQVQSCALPTDA 1158
LS + C KQ Q+ Q P +
Sbjct: 1898 LAFLSYKYCKRSKQGKTQRSQQELSPVSS 1926
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 34.3 bits (77), Expect = 0.71
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 828 KNKASRPYSISAQGVEEMDSGKQFQVP--MTKPGEVKTYRWNIPKRSGPGPSDPNCIPWV 885
+ + +RP ++ + + D K+ + P M GE T R N P S P P P C+ W
Sbjct: 291 RGRVARPPALMLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWT 350
Query: 886 YYSTVNFVKDT 896
V F T
Sbjct: 351 GDDRVFFFNPT 361
>gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]
Length = 894
Score = 32.3 bits (72), Expect = 2.7
Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 13/121 (10%)
Query: 802 PPREEHLE----LLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTK 857
PP++EHL E + + + KNK I A+ + M+ +Q +V + K
Sbjct: 463 PPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKI-IKAEMMGNMELAEQLKVQLEK 521
Query: 858 PGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGR 917
+ K IPK+SG D V V+ SG + P+ T K + ++ GR
Sbjct: 522 ANKFKETITQIPKKSGVENED--------QQEVILVRTDQSGRVWPVNTPGKSLESQGGR 573
Query: 918 R 918
R
Sbjct: 574 R 574
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,926,686
Number of Sequences: 37866
Number of extensions: 2389380
Number of successful extensions: 4412
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 4138
Number of HSP's gapped (non-prelim): 27
length of query: 1159
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1046
effective length of database: 13,968,660
effective search space: 14611218360
effective search space used: 14611218360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.