Guide to the Human Genome
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Search of human proteins with 146198575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo
sapiens]
         (333 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]   712   0.0  
gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]     103   2e-22
gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]     88   9e-18
gi|68160945 sterol-C5-desaturase [Homo sapiens]                        63   3e-10
gi|68160941 sterol-C5-desaturase [Homo sapiens]                        63   3e-10
gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]                   44   2e-04
gi|51972212 transmembrane protein 195 [Homo sapiens]                   31   1.8  
gi|149408126 nemo like kinase [Homo sapiens]                           30   3.9  
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi...    29   5.1  
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap...    29   5.1  
gi|53828672 olfactory receptor, family 4, subfamily F, member 15...    29   5.1  
gi|239755468 PREDICTED: MAS-related GPR, member G [Homo sapiens]       28   8.7  

>gi|146198575 hypothetical protein LOC10826 isoform 2 [Homo sapiens]
          Length = 333

 Score =  712 bits (1837), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MKGEAGHMLHNEKSKQEGHIWGSMRRTAFILGSGLLSFVAFWNSVTWHLQRFWGASGYFW 60
           MKGEAGHMLHNEKSKQEGHIWGSMRRTAFILGSGLLSFVAFWNSVTWHLQRFWGASGYFW
Sbjct: 1   MKGEAGHMLHNEKSKQEGHIWGSMRRTAFILGSGLLSFVAFWNSVTWHLQRFWGASGYFW 60

Query: 61  QAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVVDTTGKPNFISRYRIQVGKN 120
           QAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVVDTTGKPNFISRYRIQVGKN
Sbjct: 61  QAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVVDTTGKPNFISRYRIQVGKN 120

Query: 121 EPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRELPTFHWFLLELAIFTL 180
           EPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRELPTFHWFLLELAIFTL
Sbjct: 121 EPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRELPTFHWFLLELAIFTL 180

Query: 181 IEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVM 240
           IEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVM
Sbjct: 181 IEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVM 240

Query: 241 GSHLSSITMWFSLALIITTISHCGYHLPFLPSPEFHDYHHLKFNQCYGVLGVLDHLHGTD 300
           GSHLSSITMWFSLALIITTISHCGYHLPFLPSPEFHDYHHLKFNQCYGVLGVLDHLHGTD
Sbjct: 241 GSHLSSITMWFSLALIITTISHCGYHLPFLPSPEFHDYHHLKFNQCYGVLGVLDHLHGTD 300

Query: 301 TMFKQTKAYERHVLLLGFTPLSESIPDSPKRME 333
           TMFKQTKAYERHVLLLGFTPLSESIPDSPKRME
Sbjct: 301 TMFKQTKAYERHVLLLGFTPLSESIPDSPKRME 333


>gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]
          Length = 293

 Score =  103 bits (258), Expect = 2e-22
 Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 13/205 (6%)

Query: 109 FISRYRIQVGKNEPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRE-LPT 167
           ++ +Y+IQ  K++P       +  + +LFN   I  P++   Y F +++  P   E +P 
Sbjct: 77  YMKKYKIQ--KDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPR 134

Query: 168 FHWFLLELAIFTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAV 227
           +++ L       +IE+   Y+ HRLLHH   YK IHK HHE+ AP G+ + YAHP+E  +
Sbjct: 135 WYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLI 194

Query: 228 SNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCGYH--------LPFLPSPEFHDYH 279
                  +G +++  H+  +  W ++ L+ T   H GY         +PF      HD+H
Sbjct: 195 LG-TGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFH 253

Query: 280 HLKFNQCY-GVLGVLDHLHGTDTMF 303
           H+ F   Y       D + GTD+ +
Sbjct: 254 HMNFIGNYASTFTWWDRIFGTDSQY 278


>gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]
          Length = 162

 Score = 88.2 bits (217), Expect = 9e-18
 Identities = 47/148 (31%), Positives = 74/148 (50%), Gaps = 10/148 (6%)

Query: 165 LPTFHWFLLELAIFTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIE 224
           +P +++ L       +IE+   Y+ HRLLHH   YK IHK HHE+ AP G+ + YAHP+E
Sbjct: 1   MPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLE 60

Query: 225 HAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCGYH--------LPFLPSPEFH 276
             +       +G +++  H+  +  W ++ L+ T   H GY         +PF      H
Sbjct: 61  TLILG-TGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHH 119

Query: 277 DYHHLKFNQCY-GVLGVLDHLHGTDTMF 303
           D+HH+ F   Y       D + GTD+ +
Sbjct: 120 DFHHMNFIGNYASTFTWWDRIFGTDSQY 147


>gi|68160945 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 15/158 (9%)

Query: 164 ELPTFHWFLLELAI----FTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLY 219
           +L  F + L EL +    F    ++  Y+ HR LHH   YK++HK HH W  P    S  
Sbjct: 108 DLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHA 167

Query: 220 AHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCG------YHLPFLPSP 273
            HPI+  + + LP  + P +   H       + L  I T   H G         PF+   
Sbjct: 168 FHPIDGFLQS-LPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGS 226

Query: 274 EFHDYHHLKFNQCYGVLGVL-DHLHGTDTMFKQTKAYE 310
             H  HH+ F+  YG    L D + G+   FK   ++E
Sbjct: 227 AHHTDHHMFFDYNYGQYFTLWDRIGGS---FKNPSSFE 261


>gi|68160941 sterol-C5-desaturase [Homo sapiens]
          Length = 299

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 15/158 (9%)

Query: 164 ELPTFHWFLLELAI----FTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLY 219
           +L  F + L EL +    F    ++  Y+ HR LHH   YK++HK HH W  P    S  
Sbjct: 108 DLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHA 167

Query: 220 AHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCG------YHLPFLPSP 273
            HPI+  + + LP  + P +   H       + L  I T   H G         PF+   
Sbjct: 168 FHPIDGFLQS-LPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGS 226

Query: 274 EFHDYHHLKFNQCYGVLGVL-DHLHGTDTMFKQTKAYE 310
             H  HH+ F+  YG    L D + G+   FK   ++E
Sbjct: 227 AHHTDHHMFFDYNYGQYFTLWDRIGGS---FKNPSSFE 261


>gi|4502499 cholesterol 25-hydroxylase [Homo sapiens]
          Length = 272

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 16/160 (10%)

Query: 139 QCMISFPMVVFLYPFLKWWRDPCR--RELPTFHWFLLELAIFTLIEEVLFYYSHRLLHH- 195
           Q +    M VF    L W R P     E P     L  +    L+ ++ F+  H LLHH 
Sbjct: 90  QTLYQHVMFVFPVTLLHWARSPALLPHEAPELLLLLHHILFCLLLFDMEFFVWH-LLHHK 148

Query: 196 -PTFYKKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLA 254
            P  Y+  HK HH+ ++   + + Y    E         ++   ++G H  +   +  + 
Sbjct: 149 VPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFD-MMNVTLLGCHPLTTLTFHVVN 207

Query: 255 LIITTISHCGYHLPF-----LPSPEF-----HDYHHLKFN 284
           + ++   H GY+ P+     +P   +     HD HH  FN
Sbjct: 208 IWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFN 247


>gi|51972212 transmembrane protein 195 [Homo sapiens]
          Length = 445

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 29/126 (23%), Positives = 48/126 (38%), Gaps = 16/126 (12%)

Query: 186 FYYSHRLLHHPTFYKKIHKKHH-------EWTAPIGVISLYAHPIEHAVSNMLPVIVGPL 238
           +Y+ HR+ H        H+ HH              V+ +Y   I +   + L + + P 
Sbjct: 128 YYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFY---SPLALFIPPS 184

Query: 239 VMGSHLSSITMWFSLALIITTISHCGYHLPFLPSPEFHDYHHLKFNQCY-----GVLGVL 293
           V   HL    + +   +    I++ G     L +P  H  HH +   C      GVL + 
Sbjct: 185 VYAVHL-QFNLLYQFWIHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIW 243

Query: 294 DHLHGT 299
           D + GT
Sbjct: 244 DKIFGT 249


>gi|149408126 nemo like kinase [Homo sapiens]
          Length = 527

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 10/19 (52%), Positives = 12/19 (63%)

Query: 262 HCGYHLPFLPSPEFHDYHH 280
           H  +HLP LP P  H +HH
Sbjct: 30  HHHHHLPHLPPPHLHHHHH 48


>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
           sapiens]
          Length = 468

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 42  WNSVTWHLQRFWGASGYFWQAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVV 101
           W SVTW     W +S  F++ ++E        K +  + +  +Q  C+   +++GL  VV
Sbjct: 233 WLSVTWQDPHSWNSS--FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290

Query: 102 DTTGKPNF 109
               +  F
Sbjct: 291 QLRAQEEF 298


>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
           sapiens]
          Length = 365

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 42  WNSVTWHLQRFWGASGYFWQAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVV 101
           W SVTW     W +S  F++ ++E        K +  + +  +Q  C+   +++GL  VV
Sbjct: 233 WLSVTWQDPHSWNSS--FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290

Query: 102 DTTGKPNF 109
               +  F
Sbjct: 291 QLRAQEEF 298


>gi|53828672 olfactory receptor, family 4, subfamily F, member 15
           [Homo sapiens]
          Length = 312

 Score = 29.3 bits (64), Expect = 5.1
 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 233 VIVGPLVMGSHLSSITMWFSLA-LIITTISHCGYHLPFLPSPEFHDYHHLKFNQCYGVLG 291
           VIV  + M +HL S  M+F LA L I  ++ C    P +    F  +  + F  C   + 
Sbjct: 44  VIVFTVTMDAHLHS-PMYFLLANLSIIDMAFCSITAPKMICDIFKKHKAISFRGCITQIF 102

Query: 292 VLDHLHGTDTMFKQTKAYERHVLL 315
               L GT+ +     A++R++ +
Sbjct: 103 FSHALGGTEMVLLIAMAFDRYMAI 126


>gi|239755468 PREDICTED: MAS-related GPR, member G [Homo sapiens]
          Length = 289

 Score = 28.5 bits (62), Expect = 8.7
 Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 66  RLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLL--------------LVVDTTGKPNFIS 111
           RL     G   +LFF G   +P +F+WS   LL                V+++ KP   S
Sbjct: 195 RLYGIVLGALLVLFFCG---LPSVFYWSLQPLLNFLLPVFSPLATLLACVNSSSKPLIYS 251

Query: 112 RYRIQVGKNEPVDPVKLR 129
               Q GK EP+  V  R
Sbjct: 252 GLGRQPGKREPLRSVLRR 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.142    0.483 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,479,062
Number of Sequences: 37866
Number of extensions: 608433
Number of successful extensions: 1288
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1272
Number of HSP's gapped (non-prelim): 15
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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