Guide to the Human Genome
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Search of human proteins with 10947139

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10947139 arginase 1 [Homo sapiens]
         (322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10947139 arginase 1 [Homo sapiens]                                 650   0.0  
gi|4502215 arginase 2 precursor [Homo sapiens]                        397   e-111
gi|37537722 agmatine ureohydrolase (agmatinase) [Homo sapiens]         83   4e-16
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s...    35   0.069
gi|214832565 hypothetical protein LOC80304 isoform 2 [Homo sapiens]    34   0.20 
gi|13376798 hypothetical protein LOC80304 isoform 1 [Homo sapiens]     34   0.20 
gi|32479521 dishevelled 1 [Homo sapiens]                               29   4.9  
gi|157412259 notch1-induced protein isoform a [Homo sapiens]           29   6.4  
gi|157671913 notch1-induced protein isoform b [Homo sapiens]           29   6.4  
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]    28   8.4  

>gi|10947139 arginase 1 [Homo sapiens]
          Length = 322

 Score =  650 bits (1678), Expect = 0.0
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60
           MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
Sbjct: 1   MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60

Query: 61  DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120
           DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
Sbjct: 61  DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120

Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180
           IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
Sbjct: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180

Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240
           DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
Sbjct: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240

Query: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300
           TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
Sbjct: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300

Query: 301 LACFGLAREGNHKPIDYLNPPK 322
           LACFGLAREGNHKPIDYLNPPK
Sbjct: 301 LACFGLAREGNHKPIDYLNPPK 322


>gi|4502215 arginase 2 precursor [Homo sapiens]
          Length = 354

 Score =  397 bits (1021), Expect = e-111
 Identities = 190/316 (60%), Positives = 237/316 (75%), Gaps = 1/316 (0%)

Query: 7   TIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ- 65
           ++ +IGAPFS+GQ R GVE GP  +R+AGL+++L    C +KD+GDL F  +P D  +  
Sbjct: 25  SVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNN 84

Query: 66  IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125
           ++ NPRSVG A+++LA  V+    +G   + LGGDHSLAIG+ISGHAR  PDL V+WVDA
Sbjct: 85  LIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDA 144

Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185
           H DINTPLTT+SGNLHGQPVSFLL+EL+ K+P +PGFSW+ PCIS+  IVYIGLRDVDP 
Sbjct: 145 HADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPP 204

Query: 186 EHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATG 245
           EH+ILK   I+YFSM ++DRLGI KVME T   L+G+++RPIHLSFD+D  DP+  PATG
Sbjct: 205 EHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATG 264

Query: 246 TPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFG 305
           TPVVGGLTYREG+YI EEI+ TGLLS LD++EVNP L  + EE   T N AV +  + FG
Sbjct: 265 TPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFG 324

Query: 306 LAREGNHKPIDYLNPP 321
             REG H   D L  P
Sbjct: 325 QTREGGHIVYDQLPTP 340


>gi|37537722 agmatine ureohydrolase (agmatinase) [Homo sapiens]
          Length = 352

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 73/277 (26%), Positives = 120/277 (43%), Gaps = 36/277 (12%)

Query: 11  IGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIP--NDSPFQIV 67
           IG P   G   R G   GP  +R+  ++            +  L  AD+   N + + + 
Sbjct: 76  IGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLMVADLGDVNVNLYNLQ 135

Query: 68  KNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHT 127
            + R + +A E++          G I L LGGDH++    +   A+ H  +G++ VDAHT
Sbjct: 136 DSCRRIQEAYEKIVAA-------GCIPLTLGGDHTITYPILQAMAKKHGPVGLLHVDAHT 188

Query: 128 DINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD----VD 183
           D  T         HG P    + E                 +  K +V IG+R     +D
Sbjct: 189 D-TTDKALGEKLYHGAPFRRCVDE---------------GLLDCKRVVQIGIRGSSTTLD 232

Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243
           P  +   ++ G +     +     +  +M E    + G+   PI++SFD+D LDP++ P 
Sbjct: 233 PYRYN--RSQGFRVVLAEDCWMKSLVPLMGEVRQQMGGK---PIYISFDIDALDPAYAPG 287

Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNP 280
           TGTP + GLT  + L I        ++ G D++EV+P
Sbjct: 288 TGTPEIAGLTPSQALEIIRGCQGLNVM-GCDLVEVSP 323


>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
           sapiens]
          Length = 387

 Score = 35.4 bits (80), Expect = 0.069
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 9/98 (9%)

Query: 232 DVDGLDPSFTPATGTPVVGGLT-YREGLYITEEIYKTGLLS-GLDIMEVNPSLG-KTPEE 288
           D+  +  +F P TG  V+G LT + +G Y    I + G  S  +D+   +P +G      
Sbjct: 181 DIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGAL 240

Query: 289 VTRTVNTAVAITLACF------GLAREGNHKPIDYLNP 320
           +   V  A+ I++ CF        A+E N K I  L P
Sbjct: 241 IGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEP 278


>gi|214832565 hypothetical protein LOC80304 isoform 2 [Homo sapiens]
          Length = 622

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 97  LGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKI 156
           LG    L  G  + H  VHP  G+ W D +  + T L      LH   V F   ++ G+ 
Sbjct: 3   LGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDL-----RLHSGEVKFGDSKVIGQF 57

Query: 157 PDVPGFSWVTP 167
             V G SW  P
Sbjct: 58  ECVCGLSWAPP 68


>gi|13376798 hypothetical protein LOC80304 isoform 1 [Homo sapiens]
          Length = 721

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 97  LGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKI 156
           LG    L  G  + H  VHP  G+ W D +  + T L      LH   V F   ++ G+ 
Sbjct: 3   LGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDL-----RLHSGEVKFGDSKVIGQF 57

Query: 157 PDVPGFSWVTP 167
             V G SW  P
Sbjct: 58  ECVCGLSWAPP 68


>gi|32479521 dishevelled 1 [Homo sapiens]
          Length = 670

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 14/33 (42%), Positives = 17/33 (51%)

Query: 115 HPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSF 147
           H D G    D+HTD+  PL  T G    +P SF
Sbjct: 88  HSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF 120


>gi|157412259 notch1-induced protein isoform a [Homo sapiens]
          Length = 451

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%)

Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSG----LDIMEVNPSLGKTPEEVTRTVNTAVAIT 300
           G+P +  +TY+  LY  E I K  +       +D  E N  +G   EEV ++    V +T
Sbjct: 257 GSPDLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVT 316

Query: 301 LACFGLAREGNH 312
               G A  G H
Sbjct: 317 SEALGHA--GRH 326


>gi|157671913 notch1-induced protein isoform b [Homo sapiens]
          Length = 401

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%)

Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSG----LDIMEVNPSLGKTPEEVTRTVNTAVAIT 300
           G+P +  +TY+  LY  E I K  +       +D  E N  +G   EEV ++    V +T
Sbjct: 207 GSPDLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVT 266

Query: 301 LACFGLAREGNH 312
               G A  G H
Sbjct: 267 SEALGHA--GRH 276


>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
          Length = 6306

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 8/61 (13%)

Query: 58   IPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKN-GRISLVLGGDHSLAIGSISGHARVHP 116
            +PNDSPF +      VG  +  +  +VAE K+N   + L +  D  L +G I+ H R  P
Sbjct: 3768 LPNDSPFGL------VGWRAASVFIRVAEPKENTTTLQLQIARDKGL-LGDIAIHLRAQP 3820

Query: 117  D 117
            +
Sbjct: 3821 N 3821


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.139    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,221,021
Number of Sequences: 37866
Number of extensions: 622714
Number of successful extensions: 1192
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1181
Number of HSP's gapped (non-prelim): 13
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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