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Search of human proteins with 9966821
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7
[Homo sapiens]
(604 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom... 1236 0.0
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof... 775 0.0
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is... 766 0.0
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is... 141 2e-33
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso... 141 2e-33
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso... 137 3e-32
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H... 130 3e-30
gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof... 124 3e-28
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is... 122 9e-28
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom... 115 1e-25
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is... 100 5e-21
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is... 100 5e-21
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is... 97 4e-20
gi|154937342 ring finger protein 190 [Homo sapiens] 32 2.2
gi|154937340 ring finger protein 190 [Homo sapiens] 32 2.2
gi|45439349 selenoprotein S [Homo sapiens] 30 4.9
gi|33285002 selenoprotein S [Homo sapiens] 30 4.9
gi|19923971 coiled-coil domain containing 5 [Homo sapiens] 30 6.4
gi|217035081 aarF domain containing kinase 1 isoform b [Homo sap... 30 6.4
gi|40254938 aarF domain containing kinase 1 isoform a [Homo sapi... 30 6.4
>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
sapiens]
Length = 604
Score = 1236 bits (3198), Expect = 0.0
Identities = 604/604 (100%), Positives = 604/604 (100%)
Query: 1 MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDR 60
MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDR
Sbjct: 1 MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDR 60
Query: 61 QYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRD 120
QYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRD
Sbjct: 61 QYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRD 120
Query: 121 RNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL 180
RNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL
Sbjct: 121 RNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL 180
Query: 181 PERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDA 240
PERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDA
Sbjct: 181 PERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDA 240
Query: 241 EATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQH 300
EATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQH
Sbjct: 241 EATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQH 300
Query: 301 TEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGL 360
TEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGL
Sbjct: 301 TEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGL 360
Query: 361 TDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSE 420
TDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSE
Sbjct: 361 TDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSE 420
Query: 421 FFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKS 480
FFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKS
Sbjct: 421 FFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKS 480
Query: 481 AWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHG 540
AWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHG
Sbjct: 481 AWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHG 540
Query: 541 SWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGV 600
SWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGV
Sbjct: 541 SWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGV 600
Query: 601 QVGP 604
QVGP
Sbjct: 601 QVGP 604
>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
a [Homo sapiens]
Length = 616
Score = 775 bits (2001), Expect = 0.0
Identities = 379/611 (62%), Positives = 463/611 (75%), Gaps = 18/611 (2%)
Query: 1 MARISFSYLCPASWYFTVPTV------SPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSA 54
M RI S L PASW+F++ V + LRQ + + + + LL ++ R+
Sbjct: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQ-IMVISVLAAAVSLLYFSVVIIRNKYG 59
Query: 55 SLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLD 114
L RD++++RYLARV ++EATDT +PN+NYG+VVDCGSSGSR+FVY WPRHNGNPHDLLD
Sbjct: 60 RLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLD 119
Query: 115 IKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCT 174
I+QMRD+N +PVV KIKPGIS A +PE SDY+ PLL+FAA HVP KHKETPLYILCT
Sbjct: 120 IRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCT 179
Query: 175 AGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDH 234
AGMR+LPE +Q AIL DL+ D+P+ FDFLFS S AEVISGKQEGVYAWIGINFVLGRF+H
Sbjct: 180 AGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEH 239
Query: 235 EDESDAEATQEL---------AAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAA 285
++ D EA E+ A R+RT GILDMGG S QIAYEVP + S ++QEE A
Sbjct: 240 IEDDD-EAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVA 298
Query: 286 KILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGL 345
K LLAEFNLGCDV TEHVYRVYV TFLGFGGN ARQRYED + T+ KNRLLG++TGL
Sbjct: 299 KNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGL 358
Query: 346 SPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQ 405
+PD P+LDPCLP+ + D +++N Q +++RG GD+ C + P + ++N +Q SLNG+YQ
Sbjct: 359 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQ 418
Query: 406 SPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFS 465
PI F NSEFYGFSEF+YCTEDVLR+GG Y+ F KAA+DYC WS+L +RF GL++
Sbjct: 419 PPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYA 478
Query: 466 SHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFL 525
SHAD HRLKYQCFKSAWM++V H GF FP +Y +L+TA VYD+EVQWTLGAILY+TRFL
Sbjct: 479 SHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFL 538
Query: 526 PLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAP 585
PLRD++QE R +H W +SFVYNHYLF C LVVLLAI LYLLRLRRIH R R+S+
Sbjct: 539 PLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSA 598
Query: 586 LDLLWLEEVVP 596
LW+EE +P
Sbjct: 599 A-ALWMEEGLP 608
>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
isoform b [Homo sapiens]
Length = 608
Score = 766 bits (1978), Expect = 0.0
Identities = 378/611 (61%), Positives = 459/611 (75%), Gaps = 26/611 (4%)
Query: 1 MARISFSYLCPASWYFTVPTV------SPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSA 54
M RI S L PASW+F++ V + LRQ + + + + LL ++ R+
Sbjct: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQ-IMVISVLAAAVSLLYFSVVIIRNKYG 59
Query: 55 SLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLD 114
L RD++++RYLARV ++EATDT +PN+NYG+VVDCGSSGSR+FVY WPRHNGNPHDLLD
Sbjct: 60 RLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLD 119
Query: 115 IKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCT 174
I+QMRD+N +PVV KIKPGIS A +PE SDY+ PLL+FAA HVP KHKETPLYILCT
Sbjct: 120 IRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCT 179
Query: 175 AGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDH 234
AGMR+LPE +Q AIL DL+ D+P+ FDFLFS S AEVISGKQEGVYAWIGINFVLGRF+H
Sbjct: 180 AGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEH 239
Query: 235 EDESDAEATQEL---------AAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAA 285
++ D EA E+ A R+RT GILDMGG S QIAYEVP K EE A
Sbjct: 240 IEDDD-EAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVP--------KTEEVA 290
Query: 286 KILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGL 345
K LLAEFNLGCDV TEHVYRVYV TFLGFGGN ARQRYED + T+ KNRLLG++TGL
Sbjct: 291 KNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGL 350
Query: 346 SPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQ 405
+PD P+LDPCLP+ + D +++N Q +++RG GD+ C + P + ++N +Q SLNG+YQ
Sbjct: 351 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQ 410
Query: 406 SPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFS 465
PI F NSEFYGFSEF+YCTEDVLR+GG Y+ F KAA+DYC WS+L +RF GL++
Sbjct: 411 PPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYA 470
Query: 466 SHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFL 525
SHAD HRLKYQCFKSAWM++V H GF FP +Y +L+TA VYD+EVQWTLGAILY+TRFL
Sbjct: 471 SHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFL 530
Query: 526 PLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAP 585
PLRD++QE R +H W +SFVYNHYLF C LVVLLAI LYLLRLRRIH R R+S+
Sbjct: 531 PLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSA 590
Query: 586 LDLLWLEEVVP 596
LW+EE +P
Sbjct: 591 A-ALWMEEGLP 600
>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 2 [Homo sapiens]
Length = 517
Score = 141 bits (355), Expect = 2e-33
Identities = 125/499 (25%), Positives = 218/499 (43%), Gaps = 62/499 (12%)
Query: 81 NLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLL-DIKQMRDRNSQPVVKKIKPGISAMAD 139
N+ YG+V+D GSS + +++Y WP N ++ +++ R + PGIS
Sbjct: 53 NVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKG---------PGISKFVQ 103
Query: 140 TPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLE 199
YL + A +P +H+ETP+Y+ TAGMRLL R + LAD V D+
Sbjct: 104 KVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLL--RMESEELADRVLDVVER 161
Query: 200 --FDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGIL 257
++ F A +I+G++EG Y WI IN++LG+F + + E + T G L
Sbjct: 162 SLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYE--TNNQETFGAL 219
Query: 258 DMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNL-GCDVQHTEHVYRVYVTTFLGFG 316
D+GGAS Q+ + +P Q + +F L G D Y VY +FL +G
Sbjct: 220 DLGGASTQVTF--------VPQNQTIESPDNALQFRLYGKD-------YNVYTHSFLCYG 264
Query: 317 GNFARQRYEDLVLNETLNKNRLL-------GQKTGLSPDNPFLDPCLPVGLTDVVERN-- 367
+ A ++ L + + N +L G K ++ + + PC T E
Sbjct: 265 KDQA--LWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPC-----TKRFEMTLP 317
Query: 368 SQVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCT 425
Q ++G G++ C + L S SQ + NGI+ P+ +F FS F++
Sbjct: 318 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPL---QGDFGAFSAFYFVM 374
Query: 426 EDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQ 485
+ + + + + +C W + + + E L CF ++
Sbjct: 375 KFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSY------AGVKEKYLSEYCFSGTYILS 428
Query: 486 VLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHGSWFR 544
+L +G+HF D + ++ + + WTLG +L T +P + +H ++
Sbjct: 429 LLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAE--QPLSTPLSHSTYVF 486
Query: 545 LSFVYNHYLFFACILVVLL 563
L +++ LF I+ +L+
Sbjct: 487 LMVLFSLVLFTVAIIGLLI 505
>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 1 [Homo sapiens]
Length = 510
Score = 141 bits (355), Expect = 2e-33
Identities = 125/499 (25%), Positives = 218/499 (43%), Gaps = 62/499 (12%)
Query: 81 NLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLL-DIKQMRDRNSQPVVKKIKPGISAMAD 139
N+ YG+V+D GSS + +++Y WP N ++ +++ R + PGIS
Sbjct: 46 NVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKG---------PGISKFVQ 96
Query: 140 TPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLE 199
YL + A +P +H+ETP+Y+ TAGMRLL R + LAD V D+
Sbjct: 97 KVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLL--RMESEELADRVLDVVER 154
Query: 200 --FDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGIL 257
++ F A +I+G++EG Y WI IN++LG+F + + E + T G L
Sbjct: 155 SLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYE--TNNQETFGAL 212
Query: 258 DMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNL-GCDVQHTEHVYRVYVTTFLGFG 316
D+GGAS Q+ + +P Q + +F L G D Y VY +FL +G
Sbjct: 213 DLGGASTQVTF--------VPQNQTIESPDNALQFRLYGKD-------YNVYTHSFLCYG 257
Query: 317 GNFARQRYEDLVLNETLNKNRLL-------GQKTGLSPDNPFLDPCLPVGLTDVVERN-- 367
+ A ++ L + + N +L G K ++ + + PC T E
Sbjct: 258 KDQA--LWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPC-----TKRFEMTLP 310
Query: 368 SQVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCT 425
Q ++G G++ C + L S SQ + NGI+ P+ +F FS F++
Sbjct: 311 FQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPL---QGDFGAFSAFYFVM 367
Query: 426 EDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQ 485
+ + + + + +C W + + + E L CF ++
Sbjct: 368 KFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSY------AGVKEKYLSEYCFSGTYILS 421
Query: 486 VLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHGSWFR 544
+L +G+HF D + ++ + + WTLG +L T +P + +H ++
Sbjct: 422 LLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAE--QPLSTPLSHSTYVF 479
Query: 545 LSFVYNHYLFFACILVVLL 563
L +++ LF I+ +L+
Sbjct: 480 LMVLFSLVLFTVAIIGLLI 498
>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
isoform 1 [Homo sapiens]
Length = 495
Score = 137 bits (345), Expect = 3e-32
Identities = 143/501 (28%), Positives = 216/501 (43%), Gaps = 68/501 (13%)
Query: 78 EDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAM 137
E P L YG+V+D GSS + +F+Y WP N ++ D GIS+
Sbjct: 34 EPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSY 85
Query: 138 ADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL----PERKQLAILADLV 193
AD P AS L L A VP ++H TPLY+ TAGMRLL PE ++A
Sbjct: 86 ADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTH 145
Query: 194 KDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRT 253
FDF A ++SG++EGV+ W+ N++L F R+ T
Sbjct: 146 TLTQYPFDF----RGARILSGQEEGVFGWVTANYLLENF-----IKYGWVGRWFRPRKGT 196
Query: 254 VGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFL 313
+G +D+GGAS QI +E + PA ++ A+++ L + QH YRVY +FL
Sbjct: 197 LGAMDLGGASTQITFETTS-----PA-EDRASEVQLHLYG-----QH----YRVYTHSFL 241
Query: 314 GFGGNFARQRYEDLVLNETLNKNRL-----LGQKTGLSPDNPFLDPCLPVGLTDVVERNS 368
+G + QR +L L + G T + + + PC ++
Sbjct: 242 CYGRDQVLQR----LLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSA 297
Query: 369 QVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCTE 426
+V + G D C ++S L + S+ S+ S NG++Q P+ N F FS FFY T
Sbjct: 298 RV-SLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGN---FVAFSAFFY-TV 352
Query: 427 DVLRIGGRYHGPTFAK---AAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWM 483
D LR T + AA + C W+ L R RL C + ++
Sbjct: 353 DFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVP-------GQRARLADYCAGAMFV 405
Query: 484 YQVLHEGFHF-PYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQA--HG 540
Q+L G+ F + + + D V W LG +L T +P G+R+
Sbjct: 406 QQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIP---ADPPGLRKGTDFS 462
Query: 541 SWFRLSFVYNHYLFFACILVV 561
SW L ++ L A +L++
Sbjct: 463 SWVVLLLLFASALLAALVLLL 483
>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
sapiens]
Length = 529
Score = 130 bits (327), Expect = 3e-30
Identities = 117/463 (25%), Positives = 191/463 (41%), Gaps = 59/463 (12%)
Query: 80 PNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIK-PGISAMA 138
P L YG+V+D GSS + ++VY WP N ++ SQ +K GIS+
Sbjct: 53 PGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVV---------SQTFKCSVKGSGISSYG 103
Query: 139 DTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAI------LADL 192
+ P+ + VP H TP+++ TAGMRLL + + A +
Sbjct: 104 NNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSY 163
Query: 193 VKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRR 252
K P +F A++ISG++EGVY WI N+++G F ++
Sbjct: 164 FKSQPFDF------RGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGV----E 213
Query: 253 TVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTF 312
T G LD+GGAS QI++ V K + ++ V +VY +Y +F
Sbjct: 214 TTGALDLGGASTQISF-------VAGEKMDLNTSDIM-------QVSLYGYVYTLYTHSF 259
Query: 313 LGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPF-----LDPCLPVGLTDVVERN 367
+G N A +++ ++L + KN L F D V
Sbjct: 260 QCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNP 319
Query: 368 SQVLHVRGRGDWVSCGAMLSPLL---ARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYC 424
+ V+ G GD C ++ + A + S +G+YQ I F F+ F+Y
Sbjct: 320 NDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKI---KGPFVAFAGFYY- 375
Query: 425 TEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMY 484
T L + G + TF + ++C WS L L DE + CF + ++Y
Sbjct: 376 TASALNLSGSFSLDTFNSSTWNFCSQNWSQLP------LLLPKFDEVYARSYCFSANYIY 429
Query: 485 QVLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLP 526
+ G+ F + +P + + V + + W+LG +L T +P
Sbjct: 430 HLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIP 472
>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
2 [Homo sapiens]
Length = 472
Score = 124 bits (310), Expect = 3e-28
Identities = 138/501 (27%), Positives = 208/501 (41%), Gaps = 91/501 (18%)
Query: 78 EDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAM 137
E P L YG+V+D GSS + +F+Y WP N ++ D GIS+
Sbjct: 34 EPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSY 85
Query: 138 ADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLL----PERKQLAILADLV 193
AD P AS L L A VP ++H TPLY+ TAGMRLL PE ++A
Sbjct: 86 ADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTH 145
Query: 194 KDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRT 253
FDF A ++SG++EGV+ W+ N++L F R+ T
Sbjct: 146 TLTQYPFDF----RGARILSGQEEGVFGWVTANYLLENF-----IKYGWVGRWFRPRKGT 196
Query: 254 VGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFL 313
+G +D+GGAS QI +E + PA ++ A+++ L + QH YRVY +FL
Sbjct: 197 LGAMDLGGASTQITFETTS-----PA-EDRASEVQLHLYG-----QH----YRVYTHSFL 241
Query: 314 GFGGNFARQRYEDLVLNETLNKNRL-----LGQKTGLSPDNPFLDPCLPVGLTDVVERNS 368
+G + QR +L L + G T + + + PC ++
Sbjct: 242 CYGRDQVLQR----LLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSA 297
Query: 369 QVLHVRGRGDWVSCGAMLSPLLARSNT--SQASLNGIYQSPIDFNNSEFYGFSEFFYCTE 426
+V + G D C ++S L + S+ S+ S NG++Q P+ N F FS FFY T
Sbjct: 298 RV-SLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGN---FVAFSAFFY-TV 352
Query: 427 DVLRIGGRYHGPTFAK---AAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWM 483
D LR T + AA + C W+
Sbjct: 353 DFLRTSMGLPVATLQQLEAAAVNVCNQTWA------------------------------ 382
Query: 484 YQVLHEGFHF-PYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQA--HG 540
Q+L G+ F + + + D V W LG +L T +P G+R+
Sbjct: 383 QQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIP---ADPPGLRKGTDFS 439
Query: 541 SWFRLSFVYNHYLFFACILVV 561
SW L ++ L A +L++
Sbjct: 440 SWVVLLLLFASALLAALVLLL 460
>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
isoform 1 [Homo sapiens]
Length = 495
Score = 122 bits (306), Expect = 9e-28
Identities = 128/493 (25%), Positives = 216/493 (43%), Gaps = 76/493 (15%)
Query: 72 LEATDTEDP-NLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKI 130
+EAT P ++ +G+V D GSS + +F+Y W + N ++ SQ + ++
Sbjct: 30 VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV---------SQALACQV 80
Query: 131 K-PGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQ---- 185
+ PGIS+ A + L+ L A +P +H++TP ++ TAGMRLL +
Sbjct: 81 EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
Query: 186 --LAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEAT 243
A + ++ P++F AE+++G+ EG + WI +N+ LG +
Sbjct: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLGTL----VKYSFTG 190
Query: 244 QELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNL-GCDVQHTE 302
+ + VG LDMGGAS QI + VP + + Q A+F L G D
Sbjct: 191 EWIQPPEEMLVGALDMGGASTQITF-VPGGPILDKSTQ--------ADFRLYGSD----- 236
Query: 303 HVYRVYVTTFLGFGGNFARQR-YEDLVLNETLNKNR----LLGQKTGLSPDNPFLDPCL- 356
Y VY ++L FG + R LV + R L G +T L+ + PC+
Sbjct: 237 --YSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVH 294
Query: 357 ---PVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSN---TSQASLNGIYQSPIDF 410
P+ L Q L V G G+ +C + + L S+ + +G+YQ P+
Sbjct: 295 ATPPLSL-------PQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPL-- 345
Query: 411 NNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADE 470
+FY FS F+Y T L + R T ++C W ++ + +
Sbjct: 346 -RGQFYAFSNFYY-TFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYP-------GQD 396
Query: 471 HRLKYQCFKSAWMYQVLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLPLRD 529
L+ C ++ +LHEG+ F + +P+L + ++ WTLG +L T +P D
Sbjct: 397 RWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIP-AD 455
Query: 530 LRQEGVRQAHGSW 542
+ +++G W
Sbjct: 456 APAQWRAESYGVW 468
>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
sapiens]
Length = 428
Score = 115 bits (288), Expect = 1e-25
Identities = 115/441 (26%), Positives = 184/441 (41%), Gaps = 74/441 (16%)
Query: 84 YGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEH 143
YG++ D GS+G+RI VY + + +L+ + V +KPG+SA D P+
Sbjct: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGE---------VFDSVKPGLSAFVDQPKQ 99
Query: 144 ASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFL 203
++ ++ LL A +P K+TP+ + TAG+RLLPE K A+L + VK++ + FL
Sbjct: 100 GAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFE-VKEIFRKSPFL 158
Query: 204 FSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGAS 263
+ ++ G EG+ AW+ +NF+ G +L R+ TVG LD+GGAS
Sbjct: 159 VPKGSVSIMDGSDEGILAWVTVNFLTG--------------QLHGHRQETVGTLDLGGAS 204
Query: 264 LQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQR 323
QI + +P L E+ + L F + Y++Y ++LGFG AR
Sbjct: 205 TQITF-LPQFEKTL----EQTPRGYLTSFEM------FNSTYKLYTHSYLGFGLKAARLA 253
Query: 324 YEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCG 383
L +T + + F CLP L + V + G G
Sbjct: 254 -------------TLGALETEGTDGHTFRSACLPRWL-EAEWIFGGVKYQYGGNQEGEVG 299
Query: 384 AMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRI----GGRYHGPT 439
P A + G P + FY FS ++ D I GG
Sbjct: 300 --FEPCYAE---VLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVED 354
Query: 440 FAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPN 499
F + A++ C + F +G + C +++ +L +GF F D
Sbjct: 355 FERKAREVCDN-----LENFTSG----------SPFLCMDLSYITALLKDGFGFA-DSTV 398
Query: 500 LRTAQLVYDREVQWTLGAILY 520
L+ + V + E W LGA +
Sbjct: 399 LQLTKKVNNIETGWALGATFH 419
>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
isoform 2 [Homo sapiens]
Length = 467
Score = 100 bits (248), Expect = 5e-21
Identities = 119/443 (26%), Positives = 177/443 (39%), Gaps = 79/443 (17%)
Query: 84 YGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEH 143
YG++ D GS+G+R+ V+ + R L + K +KPG+SA AD E
Sbjct: 85 YGIMFDAGSTGTRVHVFQFTRPPRETPTL----------THETFKALKPGLSAYADDVEK 134
Query: 144 ASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFL 203
++ +R LL A +P K TPL + TAG+RLLP K +L VK++ FL
Sbjct: 135 SAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLL-QKVKEVFKASPFL 193
Query: 204 FSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGAS 263
+++G EGV AWI INF+ G L +VG+LD+GG S
Sbjct: 194 VGDDCVSIMNGTDEGVSAWITINFLTG--------------SLKTPGGSSVGMLDLGGGS 239
Query: 264 LQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQR 323
QIA+ +P L A L FN Y++Y ++LG G AR
Sbjct: 240 TQIAF-LPRVEGTLQA-SPPGYLTALRMFN---------RTYKLYSYSYLGLGLMSARL- 287
Query: 324 YEDLVLNETLNKNRLLGQKTG--LSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVS 381
+LG G + PCL E V G+
Sbjct: 288 -------------AILGGVEGQPAKDGKELVSPCLSPSFKGEWEHAEVTYRVSGQ----K 330
Query: 382 CGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRI----GGRYHG 437
A L L A + S+ N ++++ + + +FY FS ++ V I GG
Sbjct: 331 AAASLHELCA-ARVSEVLQNRVHRTE-EVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLVV 388
Query: 438 PTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFPYDY 497
F AA+ C L + ++ FS C ++ +L E F FP
Sbjct: 389 GDFEIAAKYVC----RTLETQPQSSPFS-----------CMDLTYVSLLLQE-FGFPRS- 431
Query: 498 PNLRTAQLVYDREVQWTLGAILY 520
L+ + + + E W LGAI +
Sbjct: 432 KVLKLTRKIDNVETSWALGAIFH 454
>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
isoform 1 [Homo sapiens]
Length = 484
Score = 100 bits (248), Expect = 5e-21
Identities = 119/443 (26%), Positives = 177/443 (39%), Gaps = 79/443 (17%)
Query: 84 YGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEH 143
YG++ D GS+G+R+ V+ + R L + K +KPG+SA AD E
Sbjct: 102 YGIMFDAGSTGTRVHVFQFTRPPRETPTL----------THETFKALKPGLSAYADDVEK 151
Query: 144 ASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFL 203
++ +R LL A +P K TPL + TAG+RLLP K +L VK++ FL
Sbjct: 152 SAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLL-QKVKEVFKASPFL 210
Query: 204 FSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGAS 263
+++G EGV AWI INF+ G L +VG+LD+GG S
Sbjct: 211 VGDDCVSIMNGTDEGVSAWITINFLTG--------------SLKTPGGSSVGMLDLGGGS 256
Query: 264 LQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQR 323
QIA+ +P L A L FN Y++Y ++LG G AR
Sbjct: 257 TQIAF-LPRVEGTLQA-SPPGYLTALRMFN---------RTYKLYSYSYLGLGLMSARL- 304
Query: 324 YEDLVLNETLNKNRLLGQKTG--LSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVS 381
+LG G + PCL E V G+
Sbjct: 305 -------------AILGGVEGQPAKDGKELVSPCLSPSFKGEWEHAEVTYRVSGQ----K 347
Query: 382 CGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRI----GGRYHG 437
A L L A + S+ N ++++ + + +FY FS ++ V I GG
Sbjct: 348 AAASLHELCA-ARVSEVLQNRVHRTE-EVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLVV 405
Query: 438 PTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFPYDY 497
F AA+ C L + ++ FS C ++ +L E F FP
Sbjct: 406 GDFEIAAKYVC----RTLETQPQSSPFS-----------CMDLTYVSLLLQE-FGFPRS- 448
Query: 498 PNLRTAQLVYDREVQWTLGAILY 520
L+ + + + E W LGAI +
Sbjct: 449 KVLKLTRKIDNVETSWALGAIFH 471
>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
isoform 2 [Homo sapiens]
Length = 458
Score = 97.1 bits (240), Expect = 4e-20
Identities = 122/493 (24%), Positives = 204/493 (41%), Gaps = 113/493 (22%)
Query: 72 LEATDTEDP-NLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKI 130
+EAT P ++ +G+V D GSS + +F+Y W + N ++ SQ + ++
Sbjct: 30 VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV---------SQALACQV 80
Query: 131 K-PGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQ---- 185
+ PGIS+ A + L+ L A +P +H++TP ++ TAGMRLL +
Sbjct: 81 EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
Query: 186 --LAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEAT 243
A + ++ P++F AE+++G+ EG + WI +N+ LG +
Sbjct: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLGTL----VKYSFTG 190
Query: 244 QELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNL-GCDVQHTE 302
+ + VG LDMGGAS QI + VP + + Q A+F L G D
Sbjct: 191 EWIQPPEEMLVGALDMGGASTQITF-VPGGPILDKSTQ--------ADFRLYGSD----- 236
Query: 303 HVYRVYVTTFLGFGGNFARQR-YEDLVLNETLNKNR----LLGQKTGLSPDNPFLDPCL- 356
Y VY ++L FG + R LV + R L G +T L+ + PC+
Sbjct: 237 --YSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVH 294
Query: 357 ---PVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSN---TSQASLNGIYQSPIDF 410
P+ L Q L V G G+ +C + + L S+ + +G+YQ P+
Sbjct: 295 ATPPLSL-------PQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPL-- 345
Query: 411 NNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADE 470
+FY + + P + +DYC +LT
Sbjct: 346 -RGQFYVEASY----------------PGQDRWLRDYCASGLYILT-------------- 374
Query: 471 HRLKYQCFKSAWMYQVLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLPLRD 529
+LHEG+ F + +P+L + ++ WTLG +L T +P D
Sbjct: 375 ---------------LLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIP-AD 418
Query: 530 LRQEGVRQAHGSW 542
+ +++G W
Sbjct: 419 APAQWRAESYGVW 431
>gi|154937342 ring finger protein 190 [Homo sapiens]
Length = 808
Score = 31.6 bits (70), Expect = 2.2
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 7/76 (9%)
Query: 341 QKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASL 400
Q G SP NP L+PC VG + Q +H W+ L T +
Sbjct: 663 QIAGGSPSNPLLEPCGCVG-------SLQFVHQECLKKWLKVKITSGADLGAVKTCEMCK 715
Query: 401 NGIYQSPIDFNNSEFY 416
G+ DFN EFY
Sbjct: 716 QGLLVDLGDFNMIEFY 731
>gi|154937340 ring finger protein 190 [Homo sapiens]
Length = 808
Score = 31.6 bits (70), Expect = 2.2
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 7/76 (9%)
Query: 341 QKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASL 400
Q G SP NP L+PC VG + Q +H W+ L T +
Sbjct: 663 QIAGGSPSNPLLEPCGCVG-------SLQFVHQECLKKWLKVKITSGADLGAVKTCEMCK 715
Query: 401 NGIYQSPIDFNNSEFY 416
G+ DFN EFY
Sbjct: 716 QGLLVDLGDFNMIEFY 731
>gi|45439349 selenoprotein S [Homo sapiens]
Length = 189
Score = 30.4 bits (67), Expect = 4.9
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 530 LRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYL-LRLRRIHHRQ-TRASAPLD 587
L EG+R H + L Y Y+ F+CIL L +F L RLR + RQ RA+A ++
Sbjct: 14 LETEGLRFLHTTVGSLLATYGWYIVFSCIL--LYVVFQKLSARLRALRQRQLDRAAAAVE 71
>gi|33285002 selenoprotein S [Homo sapiens]
Length = 189
Score = 30.4 bits (67), Expect = 4.9
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 530 LRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYL-LRLRRIHHRQ-TRASAPLD 587
L EG+R H + L Y Y+ F+CIL L +F L RLR + RQ RA+A ++
Sbjct: 14 LETEGLRFLHTTVGSLLATYGWYIVFSCIL--LYVVFQKLSARLRALRQRQLDRAAAAVE 71
>gi|19923971 coiled-coil domain containing 5 [Homo sapiens]
Length = 278
Score = 30.0 bits (66), Expect = 6.4
Identities = 37/159 (23%), Positives = 67/159 (42%), Gaps = 13/159 (8%)
Query: 103 PRHNGNP------HDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAA 156
P++ NP H L + ++RDR+ V++ +K S ++ D L ++F+
Sbjct: 25 PQYEVNPRTTEILHHLSERNRVRDRDVYLVIEDLKQKASEYESEAKYLQDLLMESVNFSP 84
Query: 157 AHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQ 216
A++ + L L + + L + LA V D L D ++S++E I +
Sbjct: 85 ANLSSTGSRY--LNALVDSAVALETKDTSLASFIPAVND--LTSDLFRTKSKSEEIKIEL 140
Query: 217 EGVYAWIGINFVLGRFDHEDESDAE---ATQELAAGRRR 252
E + + VL + ED AE +T+ RR
Sbjct: 141 EKLEKNLTATLVLEKCLQEDVKKAELHLSTERAKVDNRR 179
>gi|217035081 aarF domain containing kinase 1 isoform b [Homo
sapiens]
Length = 455
Score = 30.0 bits (66), Expect = 6.4
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 171 ILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVIS 213
+L A +L PE + + ++ + K+LPLE DFL AE +S
Sbjct: 127 VLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVS 169
>gi|40254938 aarF domain containing kinase 1 isoform a [Homo
sapiens]
Length = 523
Score = 30.0 bits (66), Expect = 6.4
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 171 ILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVIS 213
+L A +L PE + + ++ + K+LPLE DFL AE +S
Sbjct: 195 VLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVS 237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,759,594
Number of Sequences: 37866
Number of extensions: 1007377
Number of successful extensions: 2751
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2683
Number of HSP's gapped (non-prelim): 21
length of query: 604
length of database: 18,247,518
effective HSP length: 108
effective length of query: 496
effective length of database: 14,157,990
effective search space: 7022363040
effective search space used: 7022363040
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.