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Search of human proteins with 9506597
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens] 433 e-122
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens] 99 3e-21
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens] 81 6e-16
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 69 4e-12
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 67 1e-11
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 66 2e-11
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 60 2e-09
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 58 5e-09
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 57 9e-09
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 57 1e-08
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 57 1e-08
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 57 1e-08
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 57 1e-08
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 57 1e-08
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 55 4e-08
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 55 4e-08
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 55 4e-08
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 54 1e-07
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 51 6e-07
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 51 6e-07
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 51 6e-07
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 51 6e-07
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 51 6e-07
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 51 6e-07
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 50 1e-06
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 50 1e-06
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 49 3e-06
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 49 3e-06
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 40 0.001
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 39 0.004
>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
Length = 209
Score = 433 bits (1113), Expect = e-122
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH 60
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH
Sbjct: 1 MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH 60
Query: 61 LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA 120
LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA
Sbjct: 61 LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEA 120
Query: 121 CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGI 180
CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGI
Sbjct: 121 CSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGI 180
Query: 181 LAPQPPDVGSSDPLSMVGPSQGRSPSYAS 209
LAPQPPDVGSSDPLSMVGPSQGRSPSYAS
Sbjct: 181 LAPQPPDVGSSDPLSMVGPSQGRSPSYAS 209
>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
Length = 216
Score = 99.0 bits (245), Expect = 3e-21
Identities = 78/210 (37%), Positives = 104/210 (49%), Gaps = 22/210 (10%)
Query: 15 VSVLAGLLLGACQAHPIP--DSSPLLQFG--GQVRQRYLYTDDAQQ-TEAHLEIREDGTV 69
V +LAGL L A P+ D+ P + +G +R R+LYT + L IR DG V
Sbjct: 10 VWILAGLWL-AVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVV 68
Query: 70 GGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLE 129
A QS SLL++KA+ + I GV + R+LC DG + G L + E C+F E +
Sbjct: 69 DCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRP 128
Query: 130 DGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALP----EPPGI----- 180
DGYNVY+SE H LP+ L K + RG FLPL P LP EP +
Sbjct: 129 DGYNVYRSEKHRLPVSLSSAKQ-RQLYKNRG---FLPLSHFLPMLPMVPEEPEDLRGHLE 184
Query: 181 --LAPQPPDVGSSDPLSMV-GPSQGRSPSY 207
+ P + S DP +V G RSPS+
Sbjct: 185 SDMFSSPLETDSMDPFGLVTGLEAVRSPSF 214
>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
Length = 251
Score = 81.3 bits (199), Expect = 6e-16
Identities = 66/206 (32%), Positives = 104/206 (50%), Gaps = 17/206 (8%)
Query: 13 LWVSVLAGLL-LGACQAHPIPDSSPLL--QFGGQVRQRYLYTDDAQQTEAHLEIREDGTV 69
LWV L + + +A+P ++SPLL +GG + +LYT A+ + HL+I ++G V
Sbjct: 8 LWVCALCSVCSMSVLRAYP--NASPLLGSSWGGLI---HLYTATARNSY-HLQIHKNGHV 61
Query: 70 GGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLE 129
GA Q+ S L +++ G + I GV + R+LC G ++GS +FDPE C F+ LE
Sbjct: 62 DGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTLE 121
Query: 130 DGYNVYQSEAHGLPLHLPGNKS---PHRDPAPRGPARFLPLPGLPPAL---PEPPGILAP 183
+GY+VY S + + L K P +P P ++FL P + P
Sbjct: 122 NGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPY--SQFLSRRNEIPLIHFNTPIPRRHTR 179
Query: 184 QPPDVGSSDPLSMVGPSQGRSPSYAS 209
D DPL+++ P +P+ AS
Sbjct: 180 SAEDDSERDPLNVLKPRARMTPAPAS 205
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 68.6 bits (166), Expect = 4e-12
Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 3/99 (3%)
Query: 42 GQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRF 101
G RQR LY + HL++ DG + G +++P SLL++ ++ GV+ + GV+++ F
Sbjct: 81 GIKRQRRLYCNVG--IGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALF 138
Query: 102 LCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAH 140
+ G LY + F E C FRE LL + YN Y+S+ +
Sbjct: 139 VAMNSKGRLYATPSFQ-EECKFRETLLPNNYNAYESDLY 176
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 67.0 bits (162), Expect = 1e-11
Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 5/108 (4%)
Query: 41 GGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSR 100
GG R+R LY T+ HL++ G V G+ + S S+L++ A++ G++ I G+ + R
Sbjct: 40 GGAPRRRKLYC----ATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGR 95
Query: 101 FLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPG 148
+L G LY S H+ E C F E + E GYN Y S + PG
Sbjct: 96 YLAMNKRGRLYASEHYSAE-CEFVERIHELGYNTYASRLYRTVSSTPG 142
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 65.9 bits (159), Expect = 2e-11
Identities = 33/78 (42%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Query: 60 HLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
HL+ DG +GGA + +SLL+L ++ GV+ I GV + F+ G LYGS F E
Sbjct: 95 HLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDE 154
Query: 120 ACSFRELLLEDGYNVYQS 137
C+F+E+LL + YN Y+S
Sbjct: 155 -CTFKEILLPNNYNAYES 171
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 59.7 bits (143), Expect = 2e-09
Identities = 53/160 (33%), Positives = 72/160 (45%), Gaps = 24/160 (15%)
Query: 32 PDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAA-DQSPESLLQLKALKPGV 90
P ++ L G +R+R LY +T HL+I DG+V G D S +L+ ++ G+
Sbjct: 52 PGAAQLAHLHGILRRRQLYC----RTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGL 107
Query: 91 IQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAH-----GLPLH 145
+ I GV + +L G LYGS E C FRE E+ YN Y S + G
Sbjct: 108 VSIRGVDSGLYLGMNDKGELYGSEKLTSE-CIFREQFEENWYNTYSSNIYKHGDTGRRYF 166
Query: 146 LPGNKSPHRDPAPRGPAR---------FLPLPGLPPALPE 176
+ NK D PR AR FLP P P +PE
Sbjct: 167 VALNK----DGTPRDGARSKRHQKFTHFLPRPVDPERVPE 202
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 58.2 bits (139), Expect = 5e-09
Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 60 HLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
HL+I DG V G+ + + S+L++ A+ G++ I GV +++FL G L+ S F +
Sbjct: 100 HLQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDD 159
Query: 120 ACSFRELLLEDGYNVYQSEAH 140
C FRE E+ YN Y S H
Sbjct: 160 -CKFRERFQENSYNTYASAIH 179
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 57.4 bits (137), Expect = 9e-09
Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 14/135 (10%)
Query: 42 GQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQS-PESLLQLKALKPGVIQILGVKTSR 100
G VR R L++ T+ L+I ++G V G ++ P S+L++ +++ GV+ + + ++
Sbjct: 75 GDVRWRKLFSF----TKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNY 130
Query: 101 FLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVY-----QSEAHGLPLHLPGNKSPHRD 155
+L G LYGS F+ + C +E + E+GYN Y Q + + L G +P R
Sbjct: 131 YLAMNKKGKLYGSKEFNND-CKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRG 189
Query: 156 PAPR---GPARFLPL 167
R A FLP+
Sbjct: 190 QKTRRKNTSAHFLPM 204
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 57.0 bits (136), Expect = 1e-08
Identities = 52/160 (32%), Positives = 71/160 (44%), Gaps = 24/160 (15%)
Query: 32 PDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAA-DQSPESLLQLKALKPGV 90
P + L G +R+R LY +T HLEI +GT+ G D S +L+ ++ G+
Sbjct: 49 PAVTDLDHLKGILRRRQLYC----RTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGL 104
Query: 91 IQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAH-----GLPLH 145
+ I GV + +L G LYGS E C FRE E+ YN Y S + G +
Sbjct: 105 VSIRGVDSGLYLGMNEKGELYGSEKLTQE-CVFREQFEENWYNTYSSNLYKHVDTGRRYY 163
Query: 146 LPGNKSPHRDPAPRGPAR---------FLPLPGLPPALPE 176
+ NK D PR R FLP P P +PE
Sbjct: 164 VALNK----DGTPREGTRTKRHQKFTHFLPRPVDPDKVPE 199
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 56.6 bits (135), Expect = 1e-08
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 61 LEIREDGTVGGAADQSPESL-LQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L I DGTV G D+S + + LQL A G + I +T ++L DG LYGS E
Sbjct: 38 LRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPNE 96
Query: 120 ACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPAR--------FLPLP 168
C F E L E+ YN Y S+ H G K RGP FLPLP
Sbjct: 97 ECLFLERLEENHYNTYISKKHAEKNWFVGLKK--NGSCKRGPRTHYGQKAILFLPLP 151
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 56.6 bits (135), Expect = 1e-08
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 61 LEIREDGTVGGAADQSPESL-LQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L I DGTV G D+S + + LQL A G + I +T ++L DG LYGS E
Sbjct: 38 LRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPNE 96
Query: 120 ACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPAR--------FLPLP 168
C F E L E+ YN Y S+ H G K RGP FLPLP
Sbjct: 97 ECLFLERLEENHYNTYISKKHAEKNWFVGLKK--NGSCKRGPRTHYGQKAILFLPLP 151
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 56.6 bits (135), Expect = 1e-08
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 61 LEIREDGTVGGAADQSPESL-LQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L I DGTV G D+S + + LQL A G + I +T ++L DG LYGS E
Sbjct: 38 LRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPNE 96
Query: 120 ACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPAR--------FLPLP 168
C F E L E+ YN Y S+ H G K RGP FLPLP
Sbjct: 97 ECLFLERLEENHYNTYISKKHAEKNWFVGLKK--NGSCKRGPRTHYGQKAILFLPLP 151
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 56.6 bits (135), Expect = 1e-08
Identities = 44/117 (37%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 61 LEIREDGTVGGAADQSPESL-LQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L I DGTV G D+S + + LQL A G + I +T ++L DG LYGS E
Sbjct: 38 LRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS-QTPNE 96
Query: 120 ACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPAR--------FLPLP 168
C F E L E+ YN Y S+ H G K RGP FLPLP
Sbjct: 97 ECLFLERLEENHYNTYISKKHAEKNWFVGLKK--NGSCKRGPRTHYGQKAILFLPLP 151
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 55.1 bits (131), Expect = 4e-08
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 26/162 (16%)
Query: 60 HLEIREDGTVGGAADQSPES-LLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
+L++ DG + G D S S L L + V+ I GVKT ++ +G LY S F P
Sbjct: 87 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 146
Query: 119 EACSFRELLLEDGYNVYQS---------EAHGLPLH-----LPGNKSPHRDPAPRGPARF 164
E C F+E + E+ Y +Y S A L L+ + GN+ PA A F
Sbjct: 147 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA----AHF 201
Query: 165 LPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPS 206
LP P L A+ P + DVG + P V PS+ S S
Sbjct: 202 LPKP-LEVAMYREPSL-----HDVGETVPKPGVTPSKSTSAS 237
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 55.1 bits (131), Expect = 4e-08
Identities = 52/148 (35%), Positives = 68/148 (45%), Gaps = 22/148 (14%)
Query: 42 GQVRQRYLYTDDAQQTEAHLEIREDGTVGGAA-DQSPESLLQLKALKPGVIQILGVKTSR 100
G +R+R LY +T HLEI +GTV G D S +L+ +L G+I I GV +
Sbjct: 58 GILRRRQLYC----RTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGL 113
Query: 101 FLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNK----SPHRDP 156
+L G LYGS E C FRE E+ YN Y S L H + + ++D
Sbjct: 114 YLGMNERGELYGSKKLTRE-CVFREQFEENWYNTYAST---LYKHSDSERQYYVALNKDG 169
Query: 157 APRGPAR---------FLPLPGLPPALP 175
+PR R FLP P P LP
Sbjct: 170 SPREGYRTKRHQKFTHFLPRPVDPSKLP 197
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 55.1 bits (131), Expect = 4e-08
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 26/162 (16%)
Query: 60 HLEIREDGTVGGAADQSPES-LLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
+L++ DG + G D S S L L + V+ I GVKT ++ +G LY S F P
Sbjct: 82 YLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTP 141
Query: 119 EACSFRELLLEDGYNVYQS---------EAHGLPLH-----LPGNKSPHRDPAPRGPARF 164
E C F+E + E+ Y +Y S A L L+ + GN+ PA A F
Sbjct: 142 E-CKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPA----AHF 196
Query: 165 LPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPS 206
LP P L A+ P + DVG + P V PS+ S S
Sbjct: 197 LPKP-LEVAMYREPSL-----HDVGETVPKPGVTPSKSTSAS 232
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 53.5 bits (127), Expect = 1e-07
Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 41 GGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPE-SLLQLKALKPGVIQILGVKTS 99
GG +R R L+ +T+ +L I + G V G + ++++++ + G++ I GV++
Sbjct: 61 GGDIRVRRLFC----RTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESE 116
Query: 100 RFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQS 137
+L +G LY + E C+F+EL+LE+ YN Y S
Sbjct: 117 FYLAMNKEGKLYAKKECN-EDCNFKELILENHYNTYAS 153
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 61 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 120
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 121 E-CKFKESVFENYYVTYSS 138
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 61 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 120
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 121 E-CKFKESVFENYYVTYSS 138
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 90 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 149
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 150 E-CKFKESVFENYYVTYSS 167
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 34 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 93
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 94 E-CKFKESVFENYYVTYSS 111
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 80 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 139
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 140 E-CKFKESVFENYYVTYSS 157
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 51.2 bits (121), Expect = 6e-07
Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 60 HLEIREDGTVGGAADQ-SPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDP 118
HL+++ DGT+ G D+ S +L L + V+ I GV+T +L +G LY S F P
Sbjct: 27 HLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTP 86
Query: 119 EACSFRELLLEDGYNVYQS 137
E C F+E + E+ Y Y S
Sbjct: 87 E-CKFKESVFENYYVTYSS 104
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 50.1 bits (118), Expect = 1e-06
Identities = 32/81 (39%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 61 LEIREDGTVGGAADQS-PESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L I DG V G ++S P LQL+A + GV+ I GV +R+L + DG L S E
Sbjct: 174 LRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDE 233
Query: 120 ACSFRELLLEDGYNVYQSEAH 140
C F E L + YN Y+S +
Sbjct: 234 -CFFFERLESNNYNTYRSRKY 253
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 50.1 bits (118), Expect = 1e-06
Identities = 50/162 (30%), Positives = 75/162 (46%), Gaps = 21/162 (12%)
Query: 13 LWVSVLAGLLL-------GACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIRE 65
LW+ LA LLL G A P S P L+ G VR R L++ T L +
Sbjct: 5 LWLG-LAWLLLARAPDAAGTPSASRGPRSYPHLE--GDVRWRRLFSS----THFFLRVDP 57
Query: 66 DGTVGGAA-DQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFR 124
G V G +S+L+++++ GV+ I V + ++ G LYGS + + C FR
Sbjct: 58 GGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVD-CRFR 116
Query: 125 ELLLEDGYNVYQSE---AHGLPLHLPGNKSPHRDPAPRGPAR 163
E + E+G+N Y S+ G P+ L ++ P P G R
Sbjct: 117 ERIEENGHNTYASQRWRRRGQPMFLALDR--RGGPRPGGRTR 156
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Query: 61 LEIREDGTVGGAADQSPE-SLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L++ DGT+ G D++ + +L L + V+ I GVK S ++ +G LY S F PE
Sbjct: 23 LQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPE 82
Query: 120 ACSFRELLLEDGYNVYQS 137
C F+E + E+ Y +Y S
Sbjct: 83 -CKFKESVFENYYVIYSS 99
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Query: 61 LEIREDGTVGGAADQSPE-SLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
L++ DGT+ G D++ + +L L + V+ I GVK S ++ +G LY S F PE
Sbjct: 85 LQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPE 144
Query: 120 ACSFRELLLEDGYNVYQS 137
C F+E + E+ Y +Y S
Sbjct: 145 -CKFKESVFENYYVIYSS 161
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 40.0 bits (92), Expect = 0.001
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 11/115 (9%)
Query: 26 CQAHPI-PDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLK 84
C P PD P Q G V + + + +L+ DG++ G + + S
Sbjct: 53 CGGRPARPDRGPEPQLKGIVTKLFC------RQGFYLQANPDGSIQGTPEDT-SSFTHFN 105
Query: 85 ALKPG--VIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQS 137
+ G V+ I K ++ +G LY S HF E C F+E + E+ Y +Y S
Sbjct: 106 LIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAE-CRFKECVFENYYVLYAS 159
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 38.5 bits (88), Expect = 0.004
Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 17/134 (12%)
Query: 21 LLLGACQA----HPIPDSSPLLQFGG---------QVRQRYLYTDDAQQTEAHLEIREDG 67
LL+ CQ HP P+ + ++ G Q+R+ LY+ + + H+++
Sbjct: 16 LLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYS---RTSGKHVQVTGRR 72
Query: 68 TVGGAADQSPESLLQLKALKPGV-IQILGVKTSRFLCQRPDGALYGSLHFDPEACSFREL 126
A D + + L ++ G ++I G ++ +++C G L G + C F E+
Sbjct: 73 ISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEI 132
Query: 127 LLEDGYNVYQSEAH 140
+LE+ Y +Q+ H
Sbjct: 133 VLENNYTAFQNARH 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,148,858
Number of Sequences: 37866
Number of extensions: 701061
Number of successful extensions: 5855
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 422
Number of HSP's that attempted gapping in prelim test: 3871
Number of HSP's gapped (non-prelim): 1962
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.