Search of human proteins with 94721347

Search of human proteins with 94721347

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94721347 heparanase [Homo sapiens]
         (543 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94721347 heparanase [Homo sapiens]                                1098   0.0  
gi|148746204 heparanase [Homo sapiens]                               1098   0.0  
gi|90403586 heparanase 2 [Homo sapiens]                               438   e-123
gi|24308458 Lix1 homolog (mouse) like [Homo sapiens]                   31   2.5  
gi|189095271 phospholipase A2, group VII [Homo sapiens]                29   9.6  
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo...    29   9.6  
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo...    29   9.6  

>gi|94721347 heparanase [Homo sapiens]
          Length = 543

 Score = 1098 bits (2841), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 1   MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT 60
           MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT
Sbjct: 1   MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT 60

Query: 61  IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS 120
           IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS
Sbjct: 61  IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS 120

Query: 121 QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS 180
           QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS
Sbjct: 121 QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS 180

Query: 181 GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS 240
           GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS
Sbjct: 181 GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS 240

Query: 241 QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL 300
           QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL
Sbjct: 241 QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL 300

Query: 301 NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA 360
           NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA
Sbjct: 301 NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA 360

Query: 361 AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM 420
           AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM
Sbjct: 361 AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM 420

Query: 421 ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL 480
           ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL
Sbjct: 421 ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL 480

Query: 481 RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA 540
           RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA
Sbjct: 481 RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA 540

Query: 541 ACI 543
           ACI
Sbjct: 541 ACI 543


>gi|148746204 heparanase [Homo sapiens]
          Length = 543

 Score = 1098 bits (2841), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 1   MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT 60
           MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT
Sbjct: 1   MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT 60

Query: 61  IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS 120
           IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS
Sbjct: 61  IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS 120

Query: 121 QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS 180
           QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS
Sbjct: 121 QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS 180

Query: 181 GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS 240
           GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS
Sbjct: 181 GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS 240

Query: 241 QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL 300
           QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL
Sbjct: 241 QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL 300

Query: 301 NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA 360
           NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA
Sbjct: 301 NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA 360

Query: 361 AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM 420
           AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM
Sbjct: 361 AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM 420

Query: 421 ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL 480
           ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL
Sbjct: 421 ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL 480

Query: 481 RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA 540
           RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA
Sbjct: 481 RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA 540

Query: 541 ACI 543
           ACI
Sbjct: 541 ACI 543


>gi|90403586 heparanase 2 [Homo sapiens]
          Length = 592

 Score =  438 bits (1126), Expect = e-123
 Identities = 244/558 (43%), Positives = 328/558 (58%), Gaps = 29/558 (5%)

Query: 13  LMLLLLGPLGPLSPGALPRPAQAQD--VVDLDFFTQEPLHLVSPSFLSVTIDANLATDPR 70
           L L L    G   P  + R A  ++  ++ LD  T+ P+  V+ +FLS+ +D ++  D  
Sbjct: 33  LHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDG- 91

Query: 71  FLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIF----DPKKESTFEERSYWQSQVNQDI 126
           +L  L S +L TLARGLSPA+LRFGG +TDFL F    +P K        Y+      DI
Sbjct: 92  WLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDI 151

Query: 127 ------------CKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLY 174
                       CK    P  + E  R +      +LL+E +   + N   +  S+D LY
Sbjct: 152 VRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLY 211

Query: 175 TFANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKAD 234
            FA+CSGL LIF LNAL R  +  WNSS+A  LL Y +SK YNISWELGNEPN++     
Sbjct: 212 NFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHG 271

Query: 235 IFINGSQLGEDFIQLHKLLRK-STFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSV 293
             +NGSQLG+D+IQL  LL+    +  A LYGP++G+PR+    +L  F+K  G  +D+V
Sbjct: 272 RAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAV 331

Query: 294 TWHHYYLNGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAP 353
           TW H Y++GR     DFL   +LD     ++K+ +VV +  PGKK+WL    +   GG  
Sbjct: 332 TWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTN 391

Query: 354 LLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKL 413
            LSD++AAGF+WL+ LG+ A  GI+VV+R  FF  G  HLVD+NF+PLPDYWLSLL+K+L
Sbjct: 392 NLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRL 451

Query: 414 VGTKVLMASVQGSKRR---------KLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYL 464
           +G KVL   V G +R+         KLR+Y HCTN  N  Y  G +TL+ INLH   K +
Sbjct: 452 IGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKI 511

Query: 465 RLPYPFSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGL 524
           +L     +K V +YLL+P G  GL SKSVQLNG  L MVDD TLP L  +PLR G +L +
Sbjct: 512 KLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVI 571

Query: 525 PAFSYSFFVIRNAKVAAC 542
           P  +  FFV++N    AC
Sbjct: 572 PPVTMGFFVVKNVNALAC 589


>gi|24308458 Lix1 homolog (mouse) like [Homo sapiens]
          Length = 337

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 16/34 (47%), Positives = 20/34 (58%)

Query: 7  PALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVD 40
          PA PPP +LL   P  PL PGA   PA  ++ V+
Sbjct: 49 PAPPPPPLLLSGAPGLPLPPGAAGSPAVLREAVE 82


>gi|189095271 phospholipase A2, group VII [Homo sapiens]
          Length = 441

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 17/88 (19%)

Query: 459 NVTKYLRLPYP-----------FSNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQT 507
           N   +LRL YP             NK+    L + LG H L+   ++L      +    T
Sbjct: 76  NKGTFLRLYYPSQDNDRLDTLWIPNKEYFWGLSKFLGTHWLMGNILRL------LFGSMT 129

Query: 508 LPPLMEKPLRPGSSLGLPAFSYSFFVIR 535
            P     PLRPG    L  FS+     R
Sbjct: 130 TPANWNSPLRPGEKYPLVVFSHGLGAFR 157


>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
           sapiens]
          Length = 1057

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 15/54 (27%), Positives = 28/54 (51%)

Query: 106 PKKESTFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKK 159
           P   S  +  S  +S V     K+ +  P+ E + + +W  +++ LL+E YQK+
Sbjct: 742 PNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKE 795


>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
           sapiens]
          Length = 1083

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 15/54 (27%), Positives = 28/54 (51%)

Query: 106 PKKESTFEERSYWQSQVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKK 159
           P   S  +  S  +S V     K+ +  P+ E + + +W  +++ LL+E YQK+
Sbjct: 742 PNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKE 795


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,955,863
Number of Sequences: 37866
Number of extensions: 1035329
Number of successful extensions: 2679
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2670
Number of HSP's gapped (non-prelim): 7
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.