Search of human proteins with 92110027

Search of human proteins with 92110027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|92110027 glutaminyl-peptide cyclotransferase-like isoform 1
[Homo sapiens]
         (382 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|92110027 glutaminyl-peptide cyclotransferase-like isoform 1 [...   780   0.0  
gi|254281335 glutaminyl-peptide cyclotransferase-like isoform 2 ...   360   2e-99
gi|6912618 glutaminyl-peptide cyclotransferase precursor [Homo s...   315   3e-86
gi|55749804 aminopeptidase Fxna [Homo sapiens]                         40   0.005
gi|24307963 zinc finger, DHHC-type containing 1 [Homo sapiens]         31   2.1  
gi|115430259 solute carrier family 39 (zinc transporter), member...    30   3.6  
gi|115430255 solute carrier family 39 (zinc transporter), member...    30   3.6  
gi|57634534 nucleoporin 205kDa [Homo sapiens]                          30   3.6  
gi|4557365 Bloom syndrome protein [Homo sapiens]                       30   4.7  
gi|157502171 sorting nexin 19 [Homo sapiens]                           29   8.1  

>gi|92110027 glutaminyl-peptide cyclotransferase-like isoform 1
           [Homo sapiens]
          Length = 382

 Score =  780 bits (2013), Expect = 0.0
 Identities = 382/382 (100%), Positives = 382/382 (100%)

Query: 1   MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE 60
           MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE
Sbjct: 1   MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE 60

Query: 61  ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLE 120
           ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLE
Sbjct: 61  ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLE 120

Query: 121 ATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTP 180
           ATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTP
Sbjct: 121 ATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTP 180

Query: 181 FVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGS 240
           FVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGS
Sbjct: 181 FVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGS 240

Query: 241 RHLAQLMESIPHSPGPTRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLH 300
           RHLAQLMESIPHSPGPTRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLH
Sbjct: 241 RHLAQLMESIPHSPGPTRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLH 300

Query: 301 RLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNL 360
           RLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNL
Sbjct: 301 RLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNL 360

Query: 361 HPPTVHNLCRILAVFLAEYLGL 382
           HPPTVHNLCRILAVFLAEYLGL
Sbjct: 361 HPPTVHNLCRILAVFLAEYLGL 382


>gi|254281335 glutaminyl-peptide cyclotransferase-like isoform 2
           [Homo sapiens]
          Length = 288

 Score =  360 bits (923), Expect = 2e-99
 Identities = 171/173 (98%), Positives = 173/173 (100%)

Query: 210 KQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGPTRIQAIELFMLLD 269
           ++AAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGPTRIQAIELFMLLD
Sbjct: 116 RKAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGPTRIQAIELFMLLD 175

Query: 270 LLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHI 329
           LLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHI
Sbjct: 176 LLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHI 235

Query: 330 PFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL 382
           PFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL
Sbjct: 236 PFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL 288



 Score =  241 bits (614), Expect = 1e-63
 Identities = 120/126 (95%), Positives = 121/126 (96%)

Query: 1   MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE 60
           MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE
Sbjct: 1   MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE 60

Query: 61  ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLE 120
           ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRK   
Sbjct: 61  ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKAAP 120

Query: 121 ATLRSL 126
            TL+ L
Sbjct: 121 VTLQLL 126


>gi|6912618 glutaminyl-peptide cyclotransferase precursor [Homo
           sapiens]
          Length = 361

 Score =  315 bits (808), Expect = 3e-86
 Identities = 173/363 (47%), Positives = 222/363 (61%), Gaps = 15/363 (4%)

Query: 27  RRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTEELPLGRELRVPLIGSLPEARLRRVVG 86
           RR++  + LL L+ AL   S       G        P  +    P I  L  + LR++  
Sbjct: 7   RRVVGTLHLLLLVAALPWASR------GVSPSASAWPEEKNYHQPAI--LNSSALRQIAE 58

Query: 87  QLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTPLGPV 146
                 +W   L+PLL+ R PGSPG+   R+ +   ++ L A W +E+D F + TP G  
Sbjct: 59  GTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYR 118

Query: 147 DFGNVVATLDPRAARHLTLACHYDSKLFPP-GSTPFVGATDSAVPCALLLELAQALD--- 202
            F N+++TL+P A RHL LACHYDSK F    +  FVGATDSAVPCA++LELA+ALD   
Sbjct: 119 SFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKL 178

Query: 203 LELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGP---TRI 259
           L L         ++LQL+F DGEEA   W P+DSLYGSRHLA  M S PH PG    +++
Sbjct: 179 LSLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQL 238

Query: 260 QAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGE 319
             ++L +LLDL+GAPNPTF + FP + RWF RL++IE  LH L LL+ H  E  YFQ   
Sbjct: 239 HGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYS 298

Query: 320 PFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEY 379
             G ++DDHIPFLRRGVPVLHLI +PFP VWHT  D E NL   T+ NL +IL VF+ EY
Sbjct: 299 YGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEY 358

Query: 380 LGL 382
           L L
Sbjct: 359 LHL 361


>gi|55749804 aminopeptidase Fxna [Homo sapiens]
          Length = 904

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 24/54 (44%), Positives = 33/54 (61%), Gaps = 8/54 (14%)

Query: 150 NVVATLDPR-AARHLTLA-CHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
           NVV  L+PR  A+H  LA CH+DS    PG      A+D AV C+++LE+ + L
Sbjct: 185 NVVVKLEPRDGAQHAVLANCHFDSVANSPG------ASDDAVSCSVMLEVLRVL 232


>gi|24307963 zinc finger, DHHC-type containing 1 [Homo sapiens]
          Length = 485

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 6   RGRPRLRLGERGLMEPLLPPKRRLLPRVRLL--PLLLALAVGSAFYTIWS--GWHRRTEE 61
           R RPR+R   RGL  P   P RR +PR   L  PL L         + W+   W RR   
Sbjct: 402 RLRPRIR--RRGLGPPAAAPARRRIPRTPALCTPLALPAPTTRRRQSPWTRFQWRRRAWA 459

Query: 62  LPL 64
            PL
Sbjct: 460 APL 462


>gi|115430259 solute carrier family 39 (zinc transporter), member 4
           isoform 1 [Homo sapiens]
          Length = 622

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 11/44 (25%)

Query: 20  EPLLPPKRRLLPRVRLLPLLL-----------ALAVGSAFYTIW 52
           E L P  RRL P +RLLP ++            LAVG+AF + W
Sbjct: 455 ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSW 498


>gi|115430255 solute carrier family 39 (zinc transporter), member 4
           isoform 2 [Homo sapiens]
          Length = 647

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 11/44 (25%)

Query: 20  EPLLPPKRRLLPRVRLLPLLL-----------ALAVGSAFYTIW 52
           E L P  RRL P +RLLP ++            LAVG+AF + W
Sbjct: 480 ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSW 523


>gi|57634534 nucleoporin 205kDa [Homo sapiens]
          Length = 2012

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 8/73 (10%)

Query: 264  LFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYF----QPGE 319
            LF  L  L   N  +       + W  +  SIE R+  LN  +SH Q +++      P +
Sbjct: 1091 LFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVK 1150

Query: 320  PF----GSVEDDH 328
            P+    G +ED++
Sbjct: 1151 PYSDGEGGIEDEN 1163


>gi|4557365 Bloom syndrome protein [Homo sapiens]
          Length = 1417

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 19/97 (19%)

Query: 169 YDSKLFPPGSTPFVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEAL 228
           YD+   PP     + A+ S+  C     L+   DL+ S  K+     +  LL    + ++
Sbjct: 296 YDTDFVPPSPEEIISASSSSSKC-----LSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSM 350

Query: 229 KEWGPKDS--------------LYGSRHLAQLMESIP 251
           +E  P+ S              ++   H+ +L+++IP
Sbjct: 351 QELNPETSTDCDARQISLQQQLIHVMEHICKLIDTIP 387


>gi|157502171 sorting nexin 19 [Homo sapiens]
          Length = 992

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 37/142 (26%), Positives = 55/142 (38%), Gaps = 18/142 (12%)

Query: 86  GQLDPQRLWSTYLR---PLLVVRTPGSP-------GNLQVRKFLEATLRSLTAGWHVELD 135
           G ++P  LW  Y R   P   V +P +         NL ++  +         G HV ++
Sbjct: 181 GPVEPSHLWEAYCRATAPHPAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVE 240

Query: 136 PFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLL 195
             T +  L       +++ L      HL L   + SK   P   P       +VP +L L
Sbjct: 241 LITCNVIL------PLISRLSDPDWIHLVLVGIF-SKARDPAPCPASAPEQPSVPTSLPL 293

Query: 196 ELAQALDLELSRAKKQAAPVTL 217
            +A+   L   RA   AAPV L
Sbjct: 294 -IAEVEQLPEGRASPVAAPVFL 314


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,137,396
Number of Sequences: 37866
Number of extensions: 851366
Number of successful extensions: 1863
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1855
Number of HSP's gapped (non-prelim): 12
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.