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Search of human proteins with 91823048
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
(267 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 556 e-159
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 256 1e-68
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 255 3e-68
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 247 7e-66
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 245 3e-65
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 245 3e-65
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 241 4e-64
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 241 4e-64
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 241 4e-64
gi|11496281 kallikrein 13 precursor [Homo sapiens] 239 1e-63
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 239 2e-63
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 238 3e-63
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 238 3e-63
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 231 7e-61
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 226 2e-59
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 226 2e-59
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 218 3e-57
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 218 3e-57
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 218 3e-57
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 218 4e-57
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 217 7e-57
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 206 2e-53
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 206 2e-53
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 204 7e-53
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 203 1e-52
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 195 3e-50
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 195 3e-50
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 195 3e-50
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 191 6e-49
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 178 5e-45
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 556 bits (1434), Expect = e-159
Identities = 267/267 (100%), Positives = 267/267 (100%)
Query: 1 MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA 60
MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA
Sbjct: 1 MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA 60
Query: 61 GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN 120
GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN
Sbjct: 61 GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN 120
Query: 121 SRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQC 180
SRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQC
Sbjct: 121 SRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQC 180
Query: 181 VNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMER 240
VNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMER
Sbjct: 181 VNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMER 240
Query: 241 CALPGYPGVYTNLCKYRSWIEETMRDK 267
CALPGYPGVYTNLCKYRSWIEETMRDK
Sbjct: 241 CALPGYPGVYTNLCKYRSWIEETMRDK 267
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 256 bits (654), Expect = 1e-68
Identities = 123/260 (47%), Positives = 161/260 (61%), Gaps = 6/260 (2%)
Query: 11 WPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGG 70
WPS P L A S+ E+K++GGH C SQPWQAAL G ++ LCGG
Sbjct: 48 WPSQPSHCPRGWRSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQG--QQLLCGG 105
Query: 71 ALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS---RTHDND 127
L+ G WV+TAAHC +P V LG H+L+ + +Q + VV+ + HP YNS H++D
Sbjct: 106 VLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHD 165
Query: 128 LMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISP 187
LMLLQL+ A +G V+PI + C PG C VSGWGT++SP +P +L C + I P
Sbjct: 166 LMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 225
Query: 188 DEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYP 247
+ C+ AYP IT GMVCAG +G D+CQGDSGGPLVC G LQG+ SWG + C P
Sbjct: 226 QKKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKP 284
Query: 248 GVYTNLCKYRSWIEETMRDK 267
GVYTN+C+Y WI++ + K
Sbjct: 285 GVYTNICRYLDWIKKIIGSK 304
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 255 bits (651), Expect = 3e-68
Identities = 123/259 (47%), Positives = 164/259 (63%), Gaps = 8/259 (3%)
Query: 12 PSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGA 71
P A K ++ L L +++QED K++GGH C SQPWQAAL G ++ LCGG
Sbjct: 6 PRAAKTWMFLLLLGGAWAGHSRAQED--KVLGGHECQPHSQPWQAALFQG--QQLLCGGV 61
Query: 72 LLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS---RTHDNDL 128
L+ G WV+TAAHC +P V LG H+L+ + +Q + VV+ + HP YNS H++DL
Sbjct: 62 LVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 121
Query: 129 MLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPD 188
MLLQL+ A +G V+PI + C PG C VSGWGT++SP +P +L C + I P
Sbjct: 122 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 181
Query: 189 EVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPG 248
+ C+ AYP IT GMVCAG +G D+CQGDSGGPLVC G LQG+ SWG + C PG
Sbjct: 182 KKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
Query: 249 VYTNLCKYRSWIEETMRDK 267
VYTN+C+Y WI++ + K
Sbjct: 241 VYTNICRYLDWIKKIIGSK 259
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 247 bits (631), Expect = 7e-66
Identities = 121/258 (46%), Positives = 164/258 (63%), Gaps = 7/258 (2%)
Query: 13 SAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGAL 72
S+P + + L +LA+A T E +II G C SQPWQAAL + R LCG L
Sbjct: 27 SSPLQAMRILQLILLALA-TGLVGGETRIIKGFECKPHSQPWQAALFE--KTRLLCGATL 83
Query: 73 LSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS----RTHDNDL 128
++ +W++TAAHC +P V LG+HNL++ E +Q HP +N+ + H ND+
Sbjct: 84 IAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDI 143
Query: 129 MLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPD 188
ML+++ P I AVRP+ ++ C + GTSC +SGWG+ SSP R P +L+C NI I
Sbjct: 144 MLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
Query: 189 EVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPG 248
+ C+ AYP IT MVCA V +GGKDSCQGDSGGPLVC LQG++SWG + CA+ PG
Sbjct: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
Query: 249 VYTNLCKYRSWIEETMRD 266
VYT +CKY WI+ETM++
Sbjct: 264 VYTKVCKYVDWIQETMKN 281
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 245 bits (626), Expect = 3e-65
Identities = 118/248 (47%), Positives = 160/248 (64%), Gaps = 7/248 (2%)
Query: 24 LQVLAIAM-TQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAA 82
LQ++ +A+ T E +II G C SQPWQAAL + R LCG L++ +W++TAA
Sbjct: 4 LQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFE--KTRLLCGATLIAPRWLLTAA 61
Query: 83 HCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS----RTHDNDLMLLQLQQPAR 138
HC +P V LG+HNL++ E +Q HP +N+ + H ND+ML+++ P
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 139 IGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRT 198
I AVRP+ ++ C + GTSC +SGWG+ SSP R P +L+C NI I + C+ AYP
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 199 ITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRS 258
IT MVCA V +GGKDSCQGDSGGPLVC LQG++SWG + CA+ PGVYT +CKY
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 259 WIEETMRD 266
WI+ETM++
Sbjct: 242 WIQETMKN 249
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 245 bits (626), Expect = 3e-65
Identities = 118/248 (47%), Positives = 160/248 (64%), Gaps = 7/248 (2%)
Query: 24 LQVLAIAM-TQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAA 82
LQ++ +A+ T E +II G C SQPWQAAL + R LCG L++ +W++TAA
Sbjct: 4 LQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFE--KTRLLCGATLIAPRWLLTAA 61
Query: 83 HCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS----RTHDNDLMLLQLQQPAR 138
HC +P V LG+HNL++ E +Q HP +N+ + H ND+ML+++ P
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 139 IGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRT 198
I AVRP+ ++ C + GTSC +SGWG+ SSP R P +L+C NI I + C+ AYP
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 199 ITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRS 258
IT MVCA V +GGKDSCQGDSGGPLVC LQG++SWG + CA+ PGVYT +CKY
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 259 WIEETMRD 266
WI+ETM++
Sbjct: 242 WIQETMKN 249
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 115/234 (49%), Positives = 155/234 (66%), Gaps = 3/234 (1%)
Query: 33 QSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVA 92
+S + ++II G C +QPWQAALL P + + CG L+ QW++TAAHC + + +V
Sbjct: 59 RSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHCRKKVFRVR 117
Query: 93 LGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQA 151
LG ++L +E+ QQ+ + V+ + HP Y+ H NDLML++L + R + VRPI V+
Sbjct: 118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 152 CASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQG 211
C S GT C VSGWGT SP +P LQC+NI++ + C+ AYPR I M CAG +
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKA 236
Query: 212 GKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
G+DSCQGDSGGP+VC G LQGLVSWG CA P PGVYTNLCK+ WI+ET++
Sbjct: 237 GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 115/234 (49%), Positives = 155/234 (66%), Gaps = 3/234 (1%)
Query: 33 QSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVA 92
+S + ++II G C +QPWQAALL P + + CG L+ QW++TAAHC + + +V
Sbjct: 59 RSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHCRKKVFRVR 117
Query: 93 LGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQA 151
LG ++L +E+ QQ+ + V+ + HP Y+ H NDLML++L + R + VRPI V+
Sbjct: 118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 152 CASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQG 211
C S GT C VSGWGT SP +P LQC+NI++ + C+ AYPR I M CAG +
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKA 236
Query: 212 GKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
G+DSCQGDSGGP+VC G LQGLVSWG CA P PGVYTNLCK+ WI+ET++
Sbjct: 237 GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 115/234 (49%), Positives = 155/234 (66%), Gaps = 3/234 (1%)
Query: 33 QSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVA 92
+S + ++II G C +QPWQAALL P + + CG L+ QW++TAAHC + + +V
Sbjct: 59 RSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHCRKKVFRVR 117
Query: 93 LGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQA 151
LG ++L +E+ QQ+ + V+ + HP Y+ H NDLML++L + R + VRPI V+
Sbjct: 118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 152 CASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQG 211
C S GT C VSGWGT SP +P LQC+NI++ + C+ AYPR I M CAG +
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKA 236
Query: 212 GKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
G+DSCQGDSGGP+VC G LQGLVSWG CA P PGVYTNLCK+ WI+ET++
Sbjct: 237 GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 239 bits (611), Expect = 1e-63
Identities = 128/270 (47%), Positives = 167/270 (61%), Gaps = 23/270 (8%)
Query: 11 WPSAPKMFLLLTALQVLAIAMTQSQEDENKII----------GGHTCTRSSQPWQAALLA 60
WP A L+ A LA++ SQE +K++ GG+TC SQPWQAALL
Sbjct: 2 WPLA-----LVIASLTLALSGGVSQES-SKVLNTNGTSGFLPGGYTCFPHSQPWQAALLV 55
Query: 61 GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN 120
+ R LCGG L+ +WV+TAAHC + L+V LGKH L R EA +QV VV + HP Y
Sbjct: 56 --QGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYR 113
Query: 121 SR----THDNDLMLLQLQQPARIGRAVRPIEVTQACA-SPGTSCRVSGWGTISSPIARYP 175
HD+D+MLL+LQ P ++ ++ + ++ +PGT+CRVSGWGT +SP YP
Sbjct: 114 RSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYP 173
Query: 176 ASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVS 235
+LQC NI + DE C++ YP IT M+CAG +GGKDSC+GDSGGPLVC L G+VS
Sbjct: 174 KTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVS 233
Query: 236 WGMERCALPGYPGVYTNLCKYRSWIEETMR 265
WG C P PGVYT + +Y WI ET+R
Sbjct: 234 WGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 239 bits (609), Expect = 2e-63
Identities = 109/233 (46%), Positives = 154/233 (66%), Gaps = 6/233 (2%)
Query: 38 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97
+ + IG C +SQPWQA L R CG L+S +W++TAAHC +P L V LG+H+
Sbjct: 20 DTRAIGAEECRPNSQPWQAGLFH--LTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHH 77
Query: 98 LRRWEATQQVLRVVRQVTHPNYN----SRTHDNDLMLLQLQQPARIGRAVRPIEVTQACA 153
L +WE +Q+ RV HP +N + H++D+ML++L + AR+ AV+P+ ++Q C
Sbjct: 78 LWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCV 137
Query: 154 SPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGK 213
SPG C +SGWG +SSP A +P +LQC NI+I +++C AYP I+ M+CAG+ +GG+
Sbjct: 138 SPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGR 197
Query: 214 DSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRD 266
SCQGDSGGPLVC G L G+VS G E C+ P P VYT++C Y WI+E M +
Sbjct: 198 GSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN 250
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 238 bits (608), Expect = 3e-63
Identities = 114/248 (45%), Positives = 165/248 (66%), Gaps = 7/248 (2%)
Query: 20 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 79
L+ L ++A A E++NK++ G C ++S P+QAAL LCGG L+ WV+
Sbjct: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGH--LLCGGVLIHPLWVL 58
Query: 80 TAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARI 139
TAAHC +P LQV LGKHNLR+ E++Q+ VVR V HP+Y++ +HD D+MLL+L +PA++
Sbjct: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKL 118
Query: 140 GRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTI 199
++P+ + + C++ TSC + GWG + +P ++QC I++ E C+ AYP I
Sbjct: 119 SELIQPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQI 176
Query: 200 TPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259
T M+CAG + GKDSCQGDSGGPLVC L+GLVSWG C PGVYTN+C+Y +W
Sbjct: 177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236
Query: 260 IEETMRDK 267
I++T++ K
Sbjct: 237 IQKTIQAK 244
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 238 bits (608), Expect = 3e-63
Identities = 114/248 (45%), Positives = 165/248 (66%), Gaps = 7/248 (2%)
Query: 20 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 79
L+ L ++A A E++NK++ G C ++S P+QAAL LCGG L+ WV+
Sbjct: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGH--LLCGGVLIHPLWVL 58
Query: 80 TAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARI 139
TAAHC +P LQV LGKHNLR+ E++Q+ VVR V HP+Y++ +HD D+MLL+L +PA++
Sbjct: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKL 118
Query: 140 GRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTI 199
++P+ + + C++ TSC + GWG + +P ++QC I++ E C+ AYP I
Sbjct: 119 SELIQPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQI 176
Query: 200 TPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259
T M+CAG + GKDSCQGDSGGPLVC L+GLVSWG C PGVYTN+C+Y +W
Sbjct: 177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236
Query: 260 IEETMRDK 267
I++T++ K
Sbjct: 237 IQKTIQAK 244
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 231 bits (588), Expect = 7e-61
Identities = 121/259 (46%), Positives = 157/259 (60%), Gaps = 15/259 (5%)
Query: 17 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQ 76
M+LLLT +LA Q D +K++ G C SQPWQ AL R RF CG +L+S
Sbjct: 1 MWLLLTLSFLLASTAAQ---DGDKLLEGDECAPHSQPWQVALYE--RGRFNCGASLISPH 55
Query: 77 WVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQP 136
WV++AAHC ++V LG+HNLR+ + +Q+ R + HP Y +R+H ND+MLL+L QP
Sbjct: 56 WVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115
Query: 137 ARIGRAVRPIEVTQACASPGTSCRVSGWGTIS--------SPIAR--YPASLQCVNINIS 186
AR+ VRP + C PG +C VSGWG +S SP ++ P +L C NI+I
Sbjct: 116 ARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISII 175
Query: 187 PDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGY 246
D C K+YP +T MVCAG G +SC+GDSGGPLVC G LQG+VSWG C
Sbjct: 176 SDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTK 235
Query: 247 PGVYTNLCKYRSWIEETMR 265
PGVYT +C Y WI ETM+
Sbjct: 236 PGVYTKVCHYLEWIRETMK 254
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 226 bits (575), Expect = 2e-59
Identities = 110/250 (44%), Positives = 150/250 (60%), Gaps = 8/250 (3%)
Query: 20 LLTALQVLAIAMTQSQEDE----NKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSG 75
LL LQ+L +++ E +KII G C R S PWQ ALL+G + CGG L++
Sbjct: 5 LLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSG--NQLHCGGVLVNE 62
Query: 76 QWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQ 135
+WV+TAAHC V LG L A Q ++ + HP Y+++TH NDLML++L
Sbjct: 63 RWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
Query: 136 PARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAY 195
AR+ V+ + + C PGT+C VSGWGT +SP +P+ L CV++ + + C K Y
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 196 PRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCK 255
+ M+CAG+P K++C GDSGGPLVCRG LQGLVSWG C P PGVYT +CK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
Query: 256 YRSWIEETMR 265
+ WI +TM+
Sbjct: 241 FTKWINDTMK 250
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 226 bits (575), Expect = 2e-59
Identities = 110/250 (44%), Positives = 150/250 (60%), Gaps = 8/250 (3%)
Query: 20 LLTALQVLAIAMTQSQEDE----NKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSG 75
LL LQ+L +++ E +KII G C R S PWQ ALL+G + CGG L++
Sbjct: 5 LLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSG--NQLHCGGVLVNE 62
Query: 76 QWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQ 135
+WV+TAAHC V LG L A Q ++ + HP Y+++TH NDLML++L
Sbjct: 63 RWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
Query: 136 PARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAY 195
AR+ V+ + + C PGT+C VSGWGT +SP +P+ L CV++ + + C K Y
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 196 PRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCK 255
+ M+CAG+P K++C GDSGGPLVCRG LQGLVSWG C P PGVYT +CK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
Query: 256 YRSWIEETMR 265
+ WI +TM+
Sbjct: 241 FTKWINDTMK 250
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 218 bits (556), Expect = 3e-57
Identities = 112/260 (43%), Positives = 157/260 (60%), Gaps = 9/260 (3%)
Query: 5 VLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRR 64
+LG TW +A AL +A+ +D++KI+GG+TC +S P+Q +L +G
Sbjct: 50 LLGGRTWRAARDADGC-EALGTVAVPF----DDDDKIVGGYTCEENSLPYQVSLNSGSH- 103
Query: 65 RFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTH 124
CGG+L+S QWV++AAHC + +QV LG+HN++ E +Q + + + HP YN T
Sbjct: 104 --FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL 161
Query: 125 DNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNIN 184
DND+ML++L PA I V I + A + GT C +SGWG S A YP L+C++
Sbjct: 162 DNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAP 221
Query: 185 ISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALP 244
+ C+ +YP IT M C G +GGKDSCQ DSGGP+VC GQLQG+VSWG CA
Sbjct: 222 VLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWK 280
Query: 245 GYPGVYTNLCKYRSWIEETM 264
PGVYT + Y WI++T+
Sbjct: 281 NRPGVYTKVYNYVDWIKDTI 300
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 218 bits (556), Expect = 3e-57
Identities = 106/241 (43%), Positives = 149/241 (61%), Gaps = 4/241 (1%)
Query: 24 LQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAH 83
L + A+ +D++KI+GG+TC +S P+Q +L +G CGG+L+S QWV++AAH
Sbjct: 7 LAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH---FCGGSLISEQWVVSAAH 63
Query: 84 CGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAV 143
C + +QV LG+HN++ E +Q + + + HP YN T DND+ML++L PA I V
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
Query: 144 RPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGM 203
I + A + GT C +SGWG S A YP L+C++ + C+ +YP IT M
Sbjct: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
Query: 204 VCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEET 263
C G +GGKDSCQ DSGGP+VC GQLQG+VSWG CA PGVYT + Y WI++T
Sbjct: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDT 242
Query: 264 M 264
+
Sbjct: 243 I 243
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 218 bits (556), Expect = 3e-57
Identities = 119/254 (46%), Positives = 152/254 (59%), Gaps = 15/254 (5%)
Query: 17 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQ 76
+FLLL L + SQ KI G C R+SQPWQ L G R CGG L+ +
Sbjct: 5 IFLLLCVLGL-------SQAATPKIFNGTECGRNSQPWQVGLFEGTSLR--CGGVLIDHR 55
Query: 77 WVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY--NSRTHDNDLMLLQLQ 134
WV+TAAHC V LG+H+L + + T+Q+ VTHP Y S +H++DL LL+L+
Sbjct: 56 WVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR 115
Query: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
P R+ +V+P+ + CA+ GT C VSGWG + P +P LQC+N++I C
Sbjct: 116 LPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV 175
Query: 195 YPRTITPGMVCA-GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWG-MERCALPGYPGVYTN 252
YP IT MVCA GVP G+D+CQGDSGGPLVC G LQGLVSWG + C G PGVYT
Sbjct: 176 YPGRITSNMVCAGGVP--GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTY 233
Query: 253 LCKYRSWIEETMRD 266
+CKY WI MR+
Sbjct: 234 ICKYVDWIRMIMRN 247
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 218 bits (555), Expect = 4e-57
Identities = 107/245 (43%), Positives = 150/245 (61%), Gaps = 4/245 (1%)
Query: 20 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 79
LL L +A A+ +D++KI+GG+ C +S P+Q +L +G CGG+L+S QWV+
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYH---FCGGSLISEQWVV 59
Query: 80 TAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARI 139
+A HC + +QV LG+HN+ E +Q + + + HP YNSRT DND++L++L PA I
Sbjct: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
Query: 140 GRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTI 199
V I + A + GT +SGWG S A YP LQC++ + C+ +YP I
Sbjct: 120 NSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKI 179
Query: 200 TPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259
T M C G +GGKDSCQGDSGGP+V G+LQG+VSWG CA PGVYT + Y W
Sbjct: 180 TNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNRPGVYTKVYNYVDW 238
Query: 260 IEETM 264
I++T+
Sbjct: 239 IKDTI 243
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 217 bits (553), Expect = 7e-57
Identities = 104/244 (42%), Positives = 150/244 (61%), Gaps = 4/244 (1%)
Query: 21 LTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVIT 80
L L +A A+ +D++KI+GG+ C +S P+Q +L +G CGG+L++ QWV++
Sbjct: 4 LLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYH---FCGGSLINEQWVVS 60
Query: 81 AAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIG 140
A HC + +QV LG+HN+ E +Q + + + HP Y+ +T +ND+ML++L A I
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN 120
Query: 141 RAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTIT 200
V I + A + GT C +SGWG +S A YP LQC++ + C+ +YP IT
Sbjct: 121 ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT 180
Query: 201 PGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWI 260
M C G +GGKDSCQGDSGGP+VC GQLQG+VSWG + CA PGVYT + Y WI
Sbjct: 181 SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWI 239
Query: 261 EETM 264
+ T+
Sbjct: 240 KNTI 243
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 206 bits (524), Expect = 2e-53
Identities = 104/241 (43%), Positives = 138/241 (57%), Gaps = 5/241 (2%)
Query: 26 VLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCG 85
+L +A + ++II G C+ SQPWQAAL+ C G L+ QWV++AAHC
Sbjct: 16 ILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVM--ENELFCSGVLVHPQWVLSAAHCF 73
Query: 86 RPILQVALGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVR 144
+ + LG H+L E Q++ V HP YN NDLML++L + +R
Sbjct: 74 QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR 133
Query: 145 PIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMV 204
I + C + G SC VSGWG +++ R P LQCVN+++ +EVC K Y P M
Sbjct: 134 SISIASQCPTAGNSCLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMF 191
Query: 205 CAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETM 264
CAG KDSC GDSGGPL+C G LQGLVS+G C G PGVYTNLCK+ WIE+T+
Sbjct: 192 CAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
Query: 265 R 265
+
Sbjct: 252 Q 252
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 206 bits (524), Expect = 2e-53
Identities = 113/242 (46%), Positives = 145/242 (59%), Gaps = 15/242 (6%)
Query: 17 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQ 76
+FLLL L + SQ KI G C R+SQPWQ L G R CGG L+ +
Sbjct: 5 IFLLLCVLGL-------SQAATPKIFNGTECGRNSQPWQVGLFEGTSLR--CGGVLIDHR 55
Query: 77 WVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY--NSRTHDNDLMLLQLQ 134
WV+TAAHC V LG+H+L + + T+Q+ VTHP Y S +H++DL LL+L+
Sbjct: 56 WVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR 115
Query: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
P R+ +V+P+ + CA+ GT C VSGWG + P +P LQC+N++I C
Sbjct: 116 LPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV 175
Query: 195 YPRTITPGMVCA-GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWG-MERCALPGYPGVYTN 252
YP IT MVCA GVP G+D+CQGDSGGPLVC G LQGLVSWG + C G PGVYT
Sbjct: 176 YPGRITSNMVCAGGVP--GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTY 233
Query: 253 LC 254
+C
Sbjct: 234 IC 235
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 204 bits (519), Expect = 7e-53
Identities = 108/261 (41%), Positives = 152/261 (58%), Gaps = 18/261 (6%)
Query: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74
P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+
Sbjct: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56
Query: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDN-------- 126
QWV+TAAHC R + LG+H+L E T QV +V HP Y+ N
Sbjct: 57 PQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD 116
Query: 127 ---DLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNI 183
DLMLL+L +PA + AV+ +++ + GT+C SGWG+I P LQCV++
Sbjct: 117 SSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDL 176
Query: 184 NISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCAL 243
++ ++VC + +P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CAL
Sbjct: 177 HVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCAL 236
Query: 244 PGYPGVYTNLCKYRSWIEETM 264
P P +YT + YR WI++T+
Sbjct: 237 PERPSLYTKVVHYRKWIKDTI 257
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 203 bits (516), Expect = 1e-52
Identities = 104/238 (43%), Positives = 143/238 (60%), Gaps = 13/238 (5%)
Query: 38 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97
+++I+GG C + SQPWQ A+ + CGG L+ QWV+TAAHC + QV LG+HN
Sbjct: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWVLTAAHCLKKNSQVWLGRHN 79
Query: 98 LRRWEATQQVLRVVRQVTHPNYN-----------SRTHDNDLMLLQLQQPARIGRAVRPI 146
L E T Q + V HP YN +DLMLL+L +PA+I V+ +
Sbjct: 80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 139
Query: 147 EVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCA 206
+ + GT+C SGWG+I P SLQCV++++ +++C +AY +T M+CA
Sbjct: 140 GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCA 199
Query: 207 GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETM 264
G+ GGKD+C GDSGGPLVC G LQG+ SWG E CALP P VYT + YR WI++T+
Sbjct: 200 GLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 195 bits (496), Expect = 3e-50
Identities = 97/230 (42%), Positives = 134/230 (58%), Gaps = 12/230 (5%)
Query: 44 GHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEA 103
G C R SQPWQ +L G F C G L+ WV+TAAHCG L +G +L +
Sbjct: 49 GSPCARGSQPWQVSLFNG--LSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG 106
Query: 104 TQQVLRVVRQVTHPNYNS--------RTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP 155
+Q+ R R V HP Y+ RT ++DLMLL+L +P +G VR +++ CA P
Sbjct: 107 -EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP 165
Query: 156 GTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDS 215
G C+V+GWGT ++ +Y L C +I I + C+ YP +T M+CAG+ + G+D
Sbjct: 166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDR-GQDP 224
Query: 216 CQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
CQ DSGGPLVC LQG++SWG+ C +P VYT +CKY SWI + +R
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 195 bits (496), Expect = 3e-50
Identities = 97/230 (42%), Positives = 134/230 (58%), Gaps = 12/230 (5%)
Query: 44 GHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEA 103
G C R SQPWQ +L G F C G L+ WV+TAAHCG L +G +L +
Sbjct: 49 GSPCARGSQPWQVSLFNG--LSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG 106
Query: 104 TQQVLRVVRQVTHPNYNS--------RTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP 155
+Q+ R R V HP Y+ RT ++DLMLL+L +P +G VR +++ CA P
Sbjct: 107 -EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP 165
Query: 156 GTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDS 215
G C+V+GWGT ++ +Y L C +I I + C+ YP +T M+CAG+ + G+D
Sbjct: 166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDR-GQDP 224
Query: 216 CQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
CQ DSGGPLVC LQG++SWG+ C +P VYT +CKY SWI + +R
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 195 bits (496), Expect = 3e-50
Identities = 97/230 (42%), Positives = 134/230 (58%), Gaps = 12/230 (5%)
Query: 44 GHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEA 103
G C R SQPWQ +L G F C G L+ WV+TAAHCG L +G +L +
Sbjct: 49 GSPCARGSQPWQVSLFNG--LSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG 106
Query: 104 TQQVLRVVRQVTHPNYNS--------RTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP 155
+Q+ R R V HP Y+ RT ++DLMLL+L +P +G VR +++ CA P
Sbjct: 107 -EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP 165
Query: 156 GTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDS 215
G C+V+GWGT ++ +Y L C +I I + C+ YP +T M+CAG+ + G+D
Sbjct: 166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDR-GQDP 224
Query: 216 CQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
CQ DSGGPLVC LQG++SWG+ C +P VYT +CKY SWI + +R
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 191 bits (485), Expect = 6e-49
Identities = 101/241 (41%), Positives = 139/241 (57%), Gaps = 14/241 (5%)
Query: 38 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97
+++I+GG C + SQPWQAAL F CGG L+ QWV+TAAHC Q+ LG+HN
Sbjct: 22 QSRIVGGWECEQHSQPWQAALYHFST--FQCGGILVHRQWVLTAAHCISDNYQLWLGRHN 79
Query: 98 LRRWEATQQVLRVVRQVTHPNYNSRTHDN-----------DLMLLQLQQPA-RIGRAVRP 145
L E T Q + V HP +N +N DLMLL+L +PA I AV+
Sbjct: 80 LFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKV 139
Query: 146 IEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVC 205
+E+ G++C SGWG+I +P LQCV++ I P++ C+KA+ + +T M+C
Sbjct: 140 VELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLC 199
Query: 206 AGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
G +GGKD+C GDSGGPL+C G LQG+ SWG C P P V + Y WIE+T+
Sbjct: 200 VGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIA 259
Query: 266 D 266
+
Sbjct: 260 E 260
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 178 bits (451), Expect = 5e-45
Identities = 96/250 (38%), Positives = 138/250 (55%), Gaps = 39/250 (15%)
Query: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74
P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+
Sbjct: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56
Query: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQ 134
QWV+TAAHC + P +S +DLMLL+L
Sbjct: 57 PQWVLTAAHC-----------------------------IRKPGDDS---SHDLMLLRLS 84
Query: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
+PA + AV+ +++ + GT+C SGWG+I P LQCV++++ ++VC +
Sbjct: 85 EPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV 144
Query: 195 YPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLC 254
+P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CALP P +YT +
Sbjct: 145 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 204
Query: 255 KYRSWIEETM 264
YR WI++T+
Sbjct: 205 HYRKWIKDTI 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,753,715
Number of Sequences: 37866
Number of extensions: 570470
Number of successful extensions: 1839
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1133
Number of HSP's gapped (non-prelim): 199
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.