Search of human proteins with 89357935

Search of human proteins with 89357935

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
sapiens]
         (201 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa...   423   e-119
gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo sap...   400   e-112
gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo sa...   266   1e-71
gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo sa...   241   3e-64
gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]         76   2e-14
gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo s...    72   2e-13
gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo sa...    72   2e-13
gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo sa...    72   2e-13
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]    29   3.1  
gi|4507593 tumor necrosis factor (ligand) superfamily, member 10...    28   4.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]              28   6.9  
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]     28   6.9  
gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [...    28   6.9  
gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [...    28   6.9  

>gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
           sapiens]
          Length = 201

 Score =  423 bits (1087), Expect = e-119
 Identities = 201/201 (100%), Positives = 201/201 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFKNN 120
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFKNN
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFKNN 120

Query: 121 MDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKG 180
           MDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKG
Sbjct: 121 MDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKG 180

Query: 181 KSGPWNYNPEEVRAVLEKLHS 201
           KSGPWNYNPEEVRAVLEKLHS
Sbjct: 181 KSGPWNYNPEEVRAVLEKLHS 201


>gi|4557522 deiodinase, iodothyronine, type I isoform a [Homo
           sapiens]
          Length = 249

 Score =  400 bits (1028), Expect = e-112
 Identities = 201/249 (80%), Positives = 201/249 (80%), Gaps = 48/249 (19%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ-------- 112
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ        
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLN 120

Query: 113 ----------------------------------------DGWAFKNNMDIRNHQNLQDR 132
                                                   DGWAFKNNMDIRNHQNLQDR
Sbjct: 121 FGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDR 180

Query: 133 LQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEV 192
           LQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEV
Sbjct: 181 LQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEV 240

Query: 193 RAVLEKLHS 201
           RAVLEKLHS
Sbjct: 241 RAVLEKLHS 249


>gi|47132603 deiodinase, iodothyronine, type I isoform b [Homo
           sapiens]
          Length = 185

 Score =  266 bits (679), Expect = 1e-71
 Identities = 147/203 (72%), Positives = 158/203 (77%), Gaps = 20/203 (9%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG        +  
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTG--------NRP 52

Query: 61  WIPTFFSTQYFWFVLKV-RWQRL-EDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFK 118
            +  F S     F+ K  +++RL ED + +        V+ +     +      DGWAFK
Sbjct: 53  LVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFL----VIYIEEAHAS------DGWAFK 102

Query: 119 NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY 178
           NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY
Sbjct: 103 NNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILY 162

Query: 179 KGKSGPWNYNPEEVRAVLEKLHS 201
           KGKSGPWNYNPEEVRAVLEKLHS
Sbjct: 163 KGKSGPWNYNPEEVRAVLEKLHS 185


>gi|89357938 deiodinase, iodothyronine, type I isoform d [Homo
           sapiens]
          Length = 161

 Score =  241 bits (615), Expect = 3e-64
 Identities = 112/112 (100%), Positives = 112/112 (100%)

Query: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60
           MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN
Sbjct: 1   MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDN 60

Query: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ 112
           WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ
Sbjct: 61  WIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQ 112


>gi|55750011 deiodinase, iodothyronine, type III [Homo sapiens]
          Length = 278

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 39/87 (44%), Positives = 54/87 (62%), Gaps = 1/87 (1%)

Query: 113 DGWAFKNN-MDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYII 171
           DGW   ++   I  H++L+DR+ AA +L   +P C +V+DTM N SS  Y A  ERLY+I
Sbjct: 179 DGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVI 238

Query: 172 QEGRILYKGKSGPWNYNPEEVRAVLEK 198
           Q G I+Y+G  GP  Y   E+R  LE+
Sbjct: 239 QSGTIMYQGGRGPDGYQVSELRTWLER 265


>gi|55749998 deiodinase, iodothyronine, type II isoform b [Homo
           sapiens]
          Length = 309

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 7/93 (7%)

Query: 113 DGWAFKNN----MDIRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALP 165
           DGWA   +     +++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    
Sbjct: 204 DGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAF 263

Query: 166 ERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEK 198
           ER+ I+Q  +I Y G  GP++YN +EVR  LEK
Sbjct: 264 ERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 296


>gi|7549803 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 7/93 (7%)

Query: 113 DGWAFKNN----MDIRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALP 165
           DGWA   +     +++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    
Sbjct: 168 DGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAF 227

Query: 166 ERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEK 198
           ER+ I+Q  +I Y G  GP++YN +EVR  LEK
Sbjct: 228 ERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 260


>gi|7549805 deiodinase, iodothyronine, type II isoform a [Homo
           sapiens]
          Length = 273

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 7/93 (7%)

Query: 113 DGWAFKNN----MDIRNHQNLQDRLQAAHLLLAR---SPQCPVVVDTMQNQSSQLYAALP 165
           DGWA   +     +++ HQN +DR  AA  LL R    PQC VV D M N ++  Y    
Sbjct: 168 DGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAF 227

Query: 166 ERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEK 198
           ER+ I+Q  +I Y G  GP++YN +EVR  LEK
Sbjct: 228 ERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEK 260


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 17/83 (20%)

Query: 3   LPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAM-------------GEKTG 49
           +PQ  L ++    +   A  VVVG ++ +   DRV  ++  +             GE   
Sbjct: 163 VPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEP 222

Query: 50  MTRNPHFSHDNWIPT----FFST 68
            TR+P F+H+N + T    FFST
Sbjct: 223 QTRSPEFTHENPLETRNICFFST 245


>gi|4507593 tumor necrosis factor (ligand) superfamily, member 10
           [Homo sapiens]
          Length = 281

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 11/34 (32%), Positives = 20/34 (58%)

Query: 92  APNCPVVRLSGQRCNIWEFMQDGWAFKNNMDIRN 125
           +PN    +  G++ N WE  + G +F +N+ +RN
Sbjct: 138 SPNSKNEKALGRKINSWESSRSGHSFLSNLHLRN 171


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 3   LPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAM-------------GEKTG 49
           +PQ  L ++    +   A  VVVG ++ I   DRV  ++  +             GE   
Sbjct: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214

Query: 50  MTRNPHFSHDNWIP----TFFST 68
            TR+P  +HDN +     TFFST
Sbjct: 215 QTRSPDCTHDNPLETRNITFFST 237


>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
          Length = 2555

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 120  NMDIRNHQNLQDRLQ 134
            N+DIRNHQNL D L+
Sbjct: 1743 NVDIRNHQNLLDSLE 1757


>gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo
            sapiens]
          Length = 2554

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 120  NMDIRNHQNLQDRLQ 134
            N+DIRNHQNL D L+
Sbjct: 1741 NVDIRNHQNLLDSLE 1755


>gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo
            sapiens]
          Length = 2570

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 11/15 (73%), Positives = 13/15 (86%)

Query: 120  NMDIRNHQNLQDRLQ 134
            N+DIRNHQNL D L+
Sbjct: 1741 NVDIRNHQNLLDSLE 1755


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,944,011
Number of Sequences: 37866
Number of extensions: 309427
Number of successful extensions: 793
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 773
Number of HSP's gapped (non-prelim): 19
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.