Guide to the Human Genome
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Search of human proteins with 8923958

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923958 B-cell translocation gene 4 [Homo sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923958 B-cell translocation gene 4 [Homo sapiens]                 470   e-133
gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens]      189   2e-48
gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens]     167   5e-42
gi|5802988 B-cell translocation gene 2 [Homo sapiens]                  84   1e-16
gi|4502473 B-cell translocation protein 1 [Homo sapiens]               83   2e-16
gi|5032187 transducer of ERBB2, 1 [Homo sapiens]                       79   3e-15
gi|7706739 transducer of ERBB2, 2 [Homo sapiens]                       71   8e-13
gi|45593132 PRELI domain containing 2 isoform b [Homo sapiens]         32   0.44 
gi|33667034 PRELI domain containing 2 isoform c [Homo sapiens]         30   1.3  
gi|160358340 hypothetical protein LOC163747 isoform 2 [Homo sapi...    30   1.7  
gi|160358338 hypothetical protein LOC163747 isoform 1 [Homo sapi...    30   1.7  
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    28   4.8  
gi|27436871 carboxypeptidase O [Homo sapiens]                          28   6.3  
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]         28   8.2  

>gi|8923958 B-cell translocation gene 4 [Homo sapiens]
          Length = 223

 Score =  470 bits (1209), Expect = e-133
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI
Sbjct: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60

Query: 61  RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGR 120
           RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGR
Sbjct: 61  RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGR 120

Query: 121 WEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQS 180
           WEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQS
Sbjct: 121 WEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQS 180

Query: 181 WLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL 223
           WLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL
Sbjct: 181 WLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL 223


>gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens]
          Length = 252

 Score =  189 bits (479), Expect = 2e-48
 Identities = 96/192 (50%), Positives = 132/192 (68%), Gaps = 4/192 (2%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M++EIA  VFF TRLV+KHDKL K+ +E FAEKL  IL E Y++HW+ + PSKGQA+RCI
Sbjct: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60

Query: 61  RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGR 120
           R+N  Q  DP + +AC  S + +S LGLPKE+T+WVDP EVCCRYGEKN+ F VASF+ +
Sbjct: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK 120

Query: 121 WE-EWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPK--VSNPKSIYQV-ENLKQ 176
            E + E+ ++++ A+ + +SD  SG+S  +E  SKE  V P    +    +YQ+ E +  
Sbjct: 121 DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP 180

Query: 177 PFQSWLQIPRKK 188
           P   W  +PRKK
Sbjct: 181 PLPMWHPLPRKK 192


>gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens]
          Length = 296

 Score =  167 bits (424), Expect = 5e-42
 Identities = 96/236 (40%), Positives = 132/236 (55%), Gaps = 48/236 (20%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M++EIA  VFF TRLV+KHDKL K+ +E FAEKL  IL E Y++HW+ + PSKGQA+RCI
Sbjct: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60

Query: 61  RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCR---------------- 104
           R+N  Q  DP + +AC  S + +S LGLPKE+T+WVDP EVCCR                
Sbjct: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRRDGVSPCWPDCSQTPD 120

Query: 105 ----------------------------YGEKNHPFTVASFKGRWE-EWELYQQISYAVS 135
                                       YGEKN+ F VASF+ + E + E+ ++++ A+ 
Sbjct: 121 LVIRPPWPPKALDYRREPLRPASSFLIMYGEKNNAFIVASFENKDENKDEISRKVTRALD 180

Query: 136 RASSDVSSGTSCDEESCSKEPRVIPK--VSNPKSIYQV-ENLKQPFQSWLQIPRKK 188
           + +SD  SG+S  +E  SKE  V P    +    +YQ+ E +  P   W  +PRKK
Sbjct: 181 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKK 236


>gi|5802988 B-cell translocation gene 2 [Homo sapiens]
          Length = 158

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 47/111 (42%), Positives = 66/111 (59%), Gaps = 8/111 (7%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M  EIA  V F++ L++    +S+Q+++ F+  L   L E Y+ HW  + PSKG  +RCI
Sbjct: 9   MLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPSKGSGYRCI 68

Query: 61  RINNNQNKDPILERACVESNVDFS----HLGLPKEMTIWVDPFEVCCRYGE 107
           RIN+    DPI+ R  V S +  S    H  LP E+T+WVDP+EV  R GE
Sbjct: 69  RINHKM--DPIISR--VASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGE 115


>gi|4502473 B-cell translocation protein 1 [Homo sapiens]
          Length = 171

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 41/109 (37%), Positives = 64/109 (58%), Gaps = 4/109 (3%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M  EIA  V F+++ ++     S++Q++ F++ L  +L E Y+ HW  + P KG  +RCI
Sbjct: 11  MIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCI 70

Query: 61  RINNNQNKDPILERACVESNVDFSHLG--LPKEMTIWVDPFEVCCRYGE 107
           RIN+    DP++ +A     +    L   LP E+T+WVDP+EV  R GE
Sbjct: 71  RINHKM--DPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGE 117


>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
          Length = 345

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 39/110 (35%), Positives = 67/110 (60%), Gaps = 6/110 (5%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M+ EI   + F+   +  ++KL ++++  F E+L  +L + Y  HW+ + P KG  FRCI
Sbjct: 1   MQLEIQVALNFIISYL--YNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCI 58

Query: 61  RINNNQNKDPILERACVESNVDFSHL--GLPKEMTIWVDPFEVCCRYGEK 108
            I   +  DP++E+A  ES +D   +   LP+++++W+DPFEV  + GEK
Sbjct: 59  HI--GEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEK 106


>gi|7706739 transducer of ERBB2, 2 [Homo sapiens]
          Length = 344

 Score = 70.9 bits (172), Expect = 8e-13
 Identities = 37/110 (33%), Positives = 64/110 (58%), Gaps = 6/110 (5%)

Query: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
           M+ EI   + F+   +  ++KL +++ + F E+L  +L + Y  HW+ + P KG  FRC+
Sbjct: 1   MQLEIKVALNFIISYL--YNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCV 58

Query: 61  RINNNQNKDPILERACVESN--VDFSHLGLPKEMTIWVDPFEVCCRYGEK 108
            I   +  DP++E A   S   V+     +P+E+++W+DPFEV  + GEK
Sbjct: 59  HI--GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEK 106


>gi|45593132 PRELI domain containing 2 isoform b [Homo sapiens]
          Length = 177

 Score = 32.0 bits (71), Expect = 0.44
 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 5/109 (4%)

Query: 110 HPF--TVASFKGRWEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKS 167
           +PF   VASF  ++        IS  +     D S+G    +     +  V+P++    S
Sbjct: 13  YPFEQVVASFLRKYPNPMDKNVISVKIMEEKRDESTGVIYRKRIAICQ-NVVPEILRKVS 71

Query: 168 IYQVENLKQPFQSWLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAM 216
           I +V N++   +SWL  PR++N+   R   L  T + S K    +R +M
Sbjct: 72  ILKVPNIQLEEESWLN-PRERNMAI-RSHCLTWTQYASMKEESVFRESM 118


>gi|33667034 PRELI domain containing 2 isoform c [Homo sapiens]
          Length = 148

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)

Query: 158 VIPKVSNPKSIYQVENLKQPFQSWLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAM 216
           V+P++    SI +V N++   +SWL  PR++N+   R   L  T + S K    +R +M
Sbjct: 33  VVPEILRKVSILKVPNIQLEEESWLN-PRERNMAI-RSHCLTWTQYASMKEESVFRESM 89


>gi|160358340 hypothetical protein LOC163747 isoform 2 [Homo
           sapiens]
          Length = 418

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 17/96 (17%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 105 YGEKNHPFTVASFKGRWEEWELYQQISYAV--SRASSDVSSGTSCDEESCSKEPRVIPKV 162
           +G ++H F +++    W+++  + +  Y+   S   S +  GT   +E+C  + +++ +V
Sbjct: 29  FGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVSHIGPGTYSSKETCFSKKKLMKEV 88

Query: 163 SN--PKSIYQVENLKQPFQSWLQIPRKKNVVDGRVG 196
                K+       + P   +  I ++K + + ++G
Sbjct: 89  DTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLG 124


>gi|160358338 hypothetical protein LOC163747 isoform 1 [Homo
           sapiens]
          Length = 414

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 17/96 (17%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 105 YGEKNHPFTVASFKGRWEEWELYQQISYAV--SRASSDVSSGTSCDEESCSKEPRVIPKV 162
           +G ++H F +++    W+++  + +  Y+   S   S +  GT   +E+C  + +++ +V
Sbjct: 29  FGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVSHIGPGTYSSKETCFSKKKLMKEV 88

Query: 163 SN--PKSIYQVENLKQPFQSWLQIPRKKNVVDGRVG 196
                K+       + P   +  I ++K + + ++G
Sbjct: 89  DTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLG 124


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 135 SRASSDVSSGTSCDEESCSKEPRVIPK---VSNPKSIYQVENLKQPFQSWLQIPRKKNVV 191
           S   SD SS TS  +E   KE  + PK   VS P+ + +V   +   + W  +P     V
Sbjct: 324 SSEKSDRSSRTSSSDEEEEKE-EIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTV 382

Query: 192 DGRVGLLGNTYHGSQ 206
            G    +G   H S+
Sbjct: 383 TGCFVRIGIGNHNSK 397


>gi|27436871 carboxypeptidase O [Homo sapiens]
          Length = 374

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 9/22 (40%), Positives = 15/22 (68%)

Query: 28  EDFAEKLMTILFETYRSHWHSD 49
           E+  E ++++L + Y  HWHSD
Sbjct: 331 EETMEAVLSVLDDVYAKHWHSD 352


>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
          Length = 958

 Score = 27.7 bits (60), Expect = 8.2
 Identities = 12/35 (34%), Positives = 16/35 (45%)

Query: 139 SDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVEN 173
           SD+    +C E        + PK  NPK +Y  EN
Sbjct: 385 SDLGLNVNCQERKIESIAELQPKPYNPKKMYLTEN 419


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,064,910
Number of Sequences: 37866
Number of extensions: 403981
Number of successful extensions: 953
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 937
Number of HSP's gapped (non-prelim): 15
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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