Search of human proteins with 8922631

Search of human proteins with 8922631

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922631 exonuclease 3'-5' domain containing 2 [Homo sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922631 exonuclease 3'-5' domain containing 2 [Homo sapiens]      1016   0.0  
gi|110735439 Werner syndrome protein [Homo sapiens]                    61   3e-09
gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens]      47   5e-05
gi|4505257 moesin [Homo sapiens]                                       31   2.3  
gi|62865604 tripartite motif protein 31 [Homo sapiens]                 30   3.9  
gi|21450836 zinc finger with UFM1-specific peptidase domain [Hom...    30   3.9  
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    30   5.1  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...    29   8.6  
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    29   8.6  
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    29   8.6  

>gi|8922631 exonuclease 3'-5' domain containing 2 [Homo sapiens]
          Length = 496

 Score = 1016 bits (2628), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRG 60
           MASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRG
Sbjct: 1   MASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRG 60

Query: 61  CLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAAR 120
           CLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAAR
Sbjct: 61  CLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAAR 120

Query: 121 DAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVN 180
           DAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVN
Sbjct: 121 DAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVN 180

Query: 181 GEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDG 240
           GEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDG
Sbjct: 181 GEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDG 240

Query: 241 QPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGK 300
           QPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGK
Sbjct: 241 QPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGK 300

Query: 301 RDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPI 360
           RDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPI
Sbjct: 301 RDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPI 360

Query: 361 GSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAA 420
           GSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAA
Sbjct: 361 GSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAA 420

Query: 421 SLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNH 480
           SLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNH
Sbjct: 421 SLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNH 480

Query: 481 QKLLRKFGEDLPIQLS 496
           QKLLRKFGEDLPIQLS
Sbjct: 481 QKLLRKFGEDLPIQLS 496


>gi|110735439 Werner syndrome protein [Homo sapiens]
          Length = 1432

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 4/110 (3%)

Query: 24  PRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGL-SL 82
           P+ L  +L +  + K GVG   D  KLL+D+ + ++  ++L  +A ++   L C    SL
Sbjct: 121 PQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKK---LKCTETWSL 177

Query: 83  KSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHL 132
            SL + +L   L K   +RCSNW    LTEDQ +YAA DA     ++ +L
Sbjct: 178 NSLVKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNL 227


>gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens]
          Length = 876

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 24/151 (15%)

Query: 19  GGKTLPRTLLDILADGTILKVGVGCSEDASKL------LQDYGLVVRGCLDLRYLAMRQR 72
           G +   R +  +L+D +I K+G G   D  KL      L      + G +DL  +  + R
Sbjct: 441 GAQAFSRLVAQLLSDPSITKLGYGMVGDLQKLGTSCPALAHVEKQILGGMDLLLVHRQMR 500

Query: 73  NNLL----------CNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDA 122
              +            GLSL  L + VL   LDK+  L  SNWD   L E+QVIYAA DA
Sbjct: 501 VASVPAPAVDRARELRGLSL--LVQQVLGTALDKTQQL--SNWDRRPLCEEQVIYAAADA 556

Query: 123 ----QISVALFLHLLGYPFSRNSPGEKNDDH 149
               ++  AL      +  S +  G +   H
Sbjct: 557 YCLLEVHQALCREPARFHLSEDLAGSRRPRH 587


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 363 EEGLRLLE-DPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAAS 421
           E+  R LE + ER++ +S A  L        + KE LLQA R+   T    E++  E A 
Sbjct: 367 EQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQ---EQLALEMAE 423

Query: 422 LETRIS 427
           L  RIS
Sbjct: 424 LTARIS 429


>gi|62865604 tripartite motif protein 31 [Homo sapiens]
          Length = 425

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 18/94 (19%)

Query: 321 EMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSG 380
           E KDH SH+V L+                ++ A+ +Q  I  +E +++L+  E+  V+  
Sbjct: 119 ESKDHKSHNVSLI----------------EEAAQNYQGQI--QEQIQVLQQKEKETVQVK 160

Query: 381 ARALLNAESLPTQRKEELLQALREFYNTDVVTEE 414
           A+ +   +    Q + E  + L EF     V EE
Sbjct: 161 AQGVHRVDVFTDQVEHEKQRILTEFELLHQVLEE 194


>gi|21450836 zinc finger with UFM1-specific peptidase domain [Homo
           sapiens]
          Length = 578

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/147 (20%), Positives = 60/147 (40%), Gaps = 16/147 (10%)

Query: 295 CVVCGKRDSYIRKNVIPHEYRKH-----FPIEMKDHNSHDVL---LLCTSCHAISNYYDN 346
           C  CGK + +  +++  H   KH      P+E  D   +D     L+CT+ H +  + D 
Sbjct: 156 CPFCGKIEEH-SEDMETHVKTKHANLLDIPLEDCDQPLYDCPMCGLICTNYHILQEHVDL 214

Query: 347 HLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFY 406
           HL++   ++    +     L+L    ++ + R          S  ++++ E  Q L+  Y
Sbjct: 215 HLEENSFQQGMDRVQCSGDLQLAHQLQQEEDR-------KRRSEESRQEIEEFQKLQRQY 267

Query: 407 NTDVVTEEMLQEAASLETRISNENYVP 433
             D       Q+  ++E  ++     P
Sbjct: 268 GLDNSGGYKQQQLRNMEIEVNRGRMPP 294


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 35/163 (21%), Positives = 65/163 (39%), Gaps = 6/163 (3%)

Query: 330 VLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAES 389
           V LL   CH  S Y  +H  ++  +E +     EE  R  E+ ER +++         E 
Sbjct: 162 VKLLNRCCHLFSTYVASHKIEK--EEQEKKRKEEEERRRREEEERERLQKEEEKRRREEE 219

Query: 390 LPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRS 449
              +R+EE  + + E        ++ +  A + +T +  + Y            Q  +R 
Sbjct: 220 ERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIR- 278

Query: 450 LMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKFGEDLP 492
             QL+ +  Q ++  +    L QQ +     Q+++   G  LP
Sbjct: 279 --QLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVV-VAGSSLP 318


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
           [Homo sapiens]
          Length = 944

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 229 LYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYL 288
           L  NC     D Q  C CD  + +W  D  +       P V ++    AG+P S  DY L
Sbjct: 459 LEGNCI----DSQYYCNCDAGRNEWTSDTIVLSQKEHLP-VTQIVMTDAGQPHSEADYTL 513


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/131 (21%), Positives = 56/131 (42%), Gaps = 12/131 (9%)

Query: 306 RKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEG 365
           R+ ++  E  K    E  + +   + LL   C  +    D  +K Q  KE +     E+ 
Sbjct: 169 RQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQE----KEKR 224

Query: 366 LRLLEDPERRQVRSGARALLNAE-------SLPTQRKEELLQALREFYNTDVVTEEMLQE 418
           +  L++ E  +++S A  +++ +       +L  Q+ +EL    +E +    + E  +QE
Sbjct: 225 VTTLKE-ELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQE 283

Query: 419 AASLETRISNE 429
                TR+  E
Sbjct: 284 EEQKATRLEKE 294


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/131 (21%), Positives = 56/131 (42%), Gaps = 12/131 (9%)

Query: 306 RKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEG 365
           R+ ++  E  K    E  + +   + LL   C  +    D  +K Q  KE +     E+ 
Sbjct: 169 RQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQE----KEKR 224

Query: 366 LRLLEDPERRQVRSGARALLNAE-------SLPTQRKEELLQALREFYNTDVVTEEMLQE 418
           +  L++ E  +++S A  +++ +       +L  Q+ +EL    +E +    + E  +QE
Sbjct: 225 VTTLKE-ELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQE 283

Query: 419 AASLETRISNE 429
                TR+  E
Sbjct: 284 EEQKATRLEKE 294


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,563,811
Number of Sequences: 37866
Number of extensions: 992151
Number of successful extensions: 2584
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2578
Number of HSP's gapped (non-prelim): 11
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.