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Search of human proteins with 89142741
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 533 e-152
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 252 3e-67
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 252 3e-67
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 252 3e-67
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 219 1e-57
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 219 1e-57
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 212 3e-55
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 212 3e-55
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 212 3e-55
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 206 2e-53
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 198 4e-51
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 197 6e-51
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 197 1e-50
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 197 1e-50
gi|11496281 kallikrein 13 precursor [Homo sapiens] 196 1e-50
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 192 2e-49
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 192 3e-49
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 192 3e-49
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 192 3e-49
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 184 6e-47
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 183 1e-46
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 181 5e-46
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 177 8e-45
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 176 2e-44
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 174 5e-44
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 171 7e-43
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 152 2e-37
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 152 2e-37
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 152 2e-37
gi|4885369 granzyme M precursor [Homo sapiens] 150 1e-36
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 533 bits (1372), Expect = e-152
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVL 60
MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVL
Sbjct: 1 MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVL 60
Query: 61 VHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLI 120
VHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLI
Sbjct: 61 VHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLI 120
Query: 121 KLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK 180
KLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK
Sbjct: 121 KLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK 180
Query: 181 LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL 240
LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL
Sbjct: 181 LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL 240
Query: 241 CKFTEWIEKTVQAS 254
CKFTEWIEKTVQAS
Sbjct: 241 CKFTEWIEKTVQAS 254
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 252 bits (643), Expect = 3e-67
Identities = 132/293 (45%), Positives = 178/293 (60%), Gaps = 40/293 (13%)
Query: 1 MATAGNPWGWFLGYLI----LGVAGSLVSG------------------------------ 26
MATA PW W L LI LGV +++
Sbjct: 1 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
Query: 27 --SCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83
S S+IING DC H+QPWQAAL++ N+L+C VLVHPQW+L+AAHC + + + LG
Sbjct: 61 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143
+SL E G QM + S+ HP Y+ P +NDLMLIKL+ + + +R I+++S CP+
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 144 AGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201
AG CLVSGWG + ++ P VLQC+N+SV+S++ C Y +MFCA G +D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA-GDKAGRD 239
Query: 202 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
SC GDSGGP++CNG LQGLVS+G PC + PGVYTNLCKFT+WI++T+QA+
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 252 bits (643), Expect = 3e-67
Identities = 132/293 (45%), Positives = 178/293 (60%), Gaps = 40/293 (13%)
Query: 1 MATAGNPWGWFLGYLI----LGVAGSLVSG------------------------------ 26
MATA PW W L LI LGV +++
Sbjct: 1 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
Query: 27 --SCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83
S S+IING DC H+QPWQAAL++ N+L+C VLVHPQW+L+AAHC + + + LG
Sbjct: 61 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143
+SL E G QM + S+ HP Y+ P +NDLMLIKL+ + + +R I+++S CP+
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 144 AGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201
AG CLVSGWG + ++ P VLQC+N+SV+S++ C Y +MFCA G +D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA-GDKAGRD 239
Query: 202 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
SC GDSGGP++CNG LQGLVS+G PC + PGVYTNLCKFT+WI++T+QA+
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 252 bits (643), Expect = 3e-67
Identities = 132/293 (45%), Positives = 178/293 (60%), Gaps = 40/293 (13%)
Query: 1 MATAGNPWGWFLGYLI----LGVAGSLVSG------------------------------ 26
MATA PW W L LI LGV +++
Sbjct: 1 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
Query: 27 --SCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83
S S+IING DC H+QPWQAAL++ N+L+C VLVHPQW+L+AAHC + + + LG
Sbjct: 61 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143
+SL E G QM + S+ HP Y+ P +NDLMLIKL+ + + +R I+++S CP+
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 144 AGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201
AG CLVSGWG + ++ P VLQC+N+SV+S++ C Y +MFCA G +D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA-GDKAGRD 239
Query: 202 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
SC GDSGGP++CNG LQGLVS+G PC + PGVYTNLCKFT+WI++T+QA+
Sbjct: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 219 bits (559), Expect = 1e-57
Identities = 110/240 (45%), Positives = 151/240 (62%), Gaps = 7/240 (2%)
Query: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
L L AG G +II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC
Sbjct: 16 LALETAGEEAQGD--KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73
Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134
N YT+ LG +L + +Q ++AS S RHP Y+ NDLML+KL+ S ++
Sbjct: 74 NEYTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKK 130
Query: 135 ISIASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC 192
+ + S+C G +C VSGWG + + P+ L CV+V ++S + C+K+Y L SM C
Sbjct: 131 VRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190
Query: 193 AGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
AG +K++CNGDSGGPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++
Sbjct: 191 AGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 219 bits (559), Expect = 1e-57
Identities = 110/240 (45%), Positives = 151/240 (62%), Gaps = 7/240 (2%)
Query: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
L L AG G +II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC
Sbjct: 16 LALETAGEEAQGD--KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73
Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134
N YT+ LG +L + +Q ++AS S RHP Y+ NDLML+KL+ S ++
Sbjct: 74 NEYTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKK 130
Query: 135 ISIASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC 192
+ + S+C G +C VSGWG + + P+ L CV+V ++S + C+K+Y L SM C
Sbjct: 131 VRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190
Query: 193 AGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
AG +K++CNGDSGGPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++
Sbjct: 191 AGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 212 bits (539), Expect = 3e-55
Identities = 103/247 (41%), Positives = 154/247 (62%), Gaps = 8/247 (3%)
Query: 12 LGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAH 71
L ++L +A LV G ++II G +C PHSQPWQAAL + L C L+ P+W+L+AAH
Sbjct: 4 LQLILLALATGLVGGE-TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 72 CFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLL----ANDLMLIKLDESVS 127
C + Y + LG H+L+ + E Q A+ S HP +N L ND+ML+K+ VS
Sbjct: 63 CLKPRYIVHLGQHNLQKE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPL 185
+ +R ++++S+C TAG SCL+SGWG ++ R+P L+C N++++ + C Y
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245
+M CA KDSC GDSGGPL+CN LQG++S+G+ PC PGVYT +CK+ +
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 246 WIEKTVQ 252
WI++T++
Sbjct: 242 WIQETMK 248
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 212 bits (539), Expect = 3e-55
Identities = 103/247 (41%), Positives = 154/247 (62%), Gaps = 8/247 (3%)
Query: 12 LGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAH 71
L ++L +A LV G ++II G +C PHSQPWQAAL + L C L+ P+W+L+AAH
Sbjct: 36 LQLILLALATGLVGGE-TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
Query: 72 CFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLL----ANDLMLIKLDESVS 127
C + Y + LG H+L+ + E Q A+ S HP +N L ND+ML+K+ VS
Sbjct: 95 CLKPRYIVHLGQHNLQKE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 153
Query: 128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPL 185
+ +R ++++S+C TAG SCL+SGWG ++ R+P L+C N++++ + C Y
Sbjct: 154 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 213
Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245
+M CA KDSC GDSGGPL+CN LQG++S+G+ PC PGVYT +CK+ +
Sbjct: 214 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 273
Query: 246 WIEKTVQ 252
WI++T++
Sbjct: 274 WIQETMK 280
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 212 bits (539), Expect = 3e-55
Identities = 103/247 (41%), Positives = 154/247 (62%), Gaps = 8/247 (3%)
Query: 12 LGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAH 71
L ++L +A LV G ++II G +C PHSQPWQAAL + L C L+ P+W+L+AAH
Sbjct: 4 LQLILLALATGLVGGE-TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 72 CFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLL----ANDLMLIKLDESVS 127
C + Y + LG H+L+ + E Q A+ S HP +N L ND+ML+K+ VS
Sbjct: 63 CLKPRYIVHLGQHNLQKE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVS 121
Query: 128 ESDTIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPL 185
+ +R ++++S+C TAG SCL+SGWG ++ R+P L+C N++++ + C Y
Sbjct: 122 ITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN 181
Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245
+M CA KDSC GDSGGPL+CN LQG++S+G+ PC PGVYT +CK+ +
Sbjct: 182 ITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVD 241
Query: 246 WIEKTVQ 252
WI++T++
Sbjct: 242 WIQETMK 248
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 206 bits (524), Expect = 2e-53
Identities = 104/241 (43%), Positives = 138/241 (57%), Gaps = 5/241 (2%)
Query: 16 ILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVM--ENELFCSGVLVHPQWVLSAAHCF 73
+L +A + ++II G C+ SQPWQAAL+ C G L+ QWV++AAHC
Sbjct: 26 VLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCG 85
Query: 74 QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR 133
+ + LG H+L E Q++ V HP YN NDLML++L + +R
Sbjct: 86 RPILQVALGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVR 144
Query: 134 SISIASQCPTAGNSCLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMF 191
I + C + G SC VSGWG +++ R P LQCVN+++ +EVC K Y P M
Sbjct: 145 PIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMV 204
Query: 192 CAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
CAG KDSC GDSGGPL+C G LQGLVS+G C G PGVYTNLCK+ WIE+T+
Sbjct: 205 CAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETM 264
Query: 252 Q 252
+
Sbjct: 265 R 265
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 198 bits (503), Expect = 4e-51
Identities = 99/247 (40%), Positives = 136/247 (55%), Gaps = 7/247 (2%)
Query: 10 WFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSA 69
W L+ G +++ G +C PHSQPWQAAL +L C GVLV WVL+A
Sbjct: 12 WMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTA 71
Query: 70 AHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESV 126
AHC + YT+ LG HSL+ P Q + S+ HP YN + + DLML++L +
Sbjct: 72 AHCKKPKYTVRLGDHSLQNKDGP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQA 130
Query: 127 SESDTIRSISIASQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDP 184
S ++ IS+A C G C VSGWG + + R P L C V + ++ C Y
Sbjct: 131 SLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPG 190
Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244
M CAG D+C GDSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++
Sbjct: 191 QITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249
Query: 245 EWIEKTV 251
+WI+K +
Sbjct: 250 DWIKKII 256
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 197 bits (502), Expect = 6e-51
Identities = 96/227 (42%), Positives = 132/227 (58%), Gaps = 7/227 (3%)
Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
+++ G +C PHSQPWQAAL +L C GVLV WVL+AAHC + YT+ LG HSL+
Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136
Query: 90 QEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSISIASQCPTAGN 146
P Q + S+ HP YN + + DLML++L + S ++ IS+A C G
Sbjct: 137 DGP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Query: 147 SCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCN 204
C VSGWG + + R P L C V + ++ C Y M CAG D+C
Sbjct: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQ 254
Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
GDSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++ +WI+K +
Sbjct: 255 GDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 197 bits (500), Expect = 1e-50
Identities = 93/239 (38%), Positives = 137/239 (57%), Gaps = 1/239 (0%)
Query: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
++L + + + +++++G C S P+QAAL L C GVL+HP WVL+AAHC +
Sbjct: 6 VVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK 65
Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134
+ + LG H+L +E + +V HP+Y+ D+ML++L S+ I+
Sbjct: 66 PNLQVFLGKHNLR-QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP 124
Query: 135 ISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAG 194
+ + C SC + GWG A+G P +QC + +VS E C Y +M CAG
Sbjct: 125 LPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184
Query: 195 GGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253
KDSC GDSGGPL+C +L+GLVS+G PCG PGVYTN+C++T WI+KT+QA
Sbjct: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 197 bits (500), Expect = 1e-50
Identities = 93/239 (38%), Positives = 137/239 (57%), Gaps = 1/239 (0%)
Query: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
++L + + + +++++G C S P+QAAL L C GVL+HP WVL+AAHC +
Sbjct: 6 VVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK 65
Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134
+ + LG H+L +E + +V HP+Y+ D+ML++L S+ I+
Sbjct: 66 PNLQVFLGKHNLR-QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP 124
Query: 135 ISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAG 194
+ + C SC + GWG A+G P +QC + +VS E C Y +M CAG
Sbjct: 125 LPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184
Query: 195 GGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253
KDSC GDSGGPL+C +L+GLVS+G PCG PGVYTN+C++T WI+KT+QA
Sbjct: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 196 bits (499), Expect = 1e-50
Identities = 108/263 (41%), Positives = 153/263 (58%), Gaps = 19/263 (7%)
Query: 7 PWGWFLGYLILGVAGSLVSGSCSQIIN----------GEDCSPHSQPWQAALVMENELFC 56
P + L L ++G VS S+++N G C PHSQPWQAAL+++ L C
Sbjct: 3 PLALVIASLTLALSGG-VSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLC 61
Query: 57 SGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-PLLAN 115
GVLVHP+WVL+AAHC + + LG H+L E G Q+ E S+ HPEY R P N
Sbjct: 62 GGVLVHPKWVLTAAHCLKEGLKVYLGKHAL-GRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
Query: 116 ---DLMLIKLDESVSESDTIRSISIA-SQCPTAGNSCLVSGWGLLANGRM--PTVLQCVN 169
D+ML++L V + I+++ ++ + T G +C VSGWG + ++ P LQC N
Sbjct: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCAN 180
Query: 170 VSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCG 229
+ + S+E C ++Y +M CAG KDSC GDSGGPL+CN L G+VS+G PCG
Sbjct: 181 IQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCG 240
Query: 230 QVGVPGVYTNLCKFTEWIEKTVQ 252
Q PGVYT + ++ WI +T++
Sbjct: 241 QPDRPGVYTRVSRYVLWIRETIR 263
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 192 bits (488), Expect = 2e-49
Identities = 96/239 (40%), Positives = 137/239 (57%), Gaps = 14/239 (5%)
Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
S+I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L
Sbjct: 23 SRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFE 82
Query: 89 DQEPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISI 137
++ G Q V S S HP YN LL ++DLML++L E +D ++ + +
Sbjct: 83 PEDTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
Query: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195
+Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG
Sbjct: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
Query: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A+
Sbjct: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 192 bits (487), Expect = 3e-49
Identities = 96/239 (40%), Positives = 137/239 (57%), Gaps = 14/239 (5%)
Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
S+I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL
Sbjct: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISI 137
++ G Q+ + S S HP Y+ LL N DLML++L E +D ++ + +
Sbjct: 83 PEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141
Query: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195
+Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG
Sbjct: 142 PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR 201
Query: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+
Sbjct: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 192 bits (487), Expect = 3e-49
Identities = 103/239 (43%), Positives = 144/239 (60%), Gaps = 8/239 (3%)
Query: 14 YLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF 73
+L+L V G L + +I NG +C +SQPWQ L L C GVL+ +WVL+AAHC
Sbjct: 6 FLLLCVLG-LSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCS 64
Query: 74 QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDESVSESDT 131
+ Y + LG HSL + + Q+ + SV HP Y + +DL L++L V + +
Sbjct: 65 GSRYWVRLGEHSL-SQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123
Query: 132 IRSISIASQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPS 189
++ + + + C TAG C VSGWG+ + R P +LQC+N+S+VS C +Y +
Sbjct: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183
Query: 190 MFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGK-APCGQVGVPGVYTNLCKFTEWI 247
M CAGG Q D+C GDSGGPL+C G LQGLVS+G PCGQ G+PGVYT +CK+ +WI
Sbjct: 184 MVCAGGVPGQ-DACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWI 241
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 192 bits (487), Expect = 3e-49
Identities = 90/235 (38%), Positives = 130/235 (55%), Gaps = 13/235 (5%)
Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
+++ G++C+PHSQPWQ AL C L+ P WVLSAAHC + LG H+L
Sbjct: 21 KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKR 80
Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149
P Q+ S + HP Y ND+ML++L + + +R + ++CP G +C+
Sbjct: 81 DGP-EQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACV 139
Query: 150 VSGWGLLANGR------------MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197
VSGWGL+++ +P L C N+S++S+ C K Y +M CAG
Sbjct: 140 VSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEG 199
Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
+SC GDSGGPL+C G LQG+VS+G PC PGVYT +C + EWI +T++
Sbjct: 200 RGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMK 254
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 184 bits (467), Expect = 6e-47
Identities = 101/258 (39%), Positives = 143/258 (55%), Gaps = 17/258 (6%)
Query: 10 WFLGY-LILGVAGSLVSGSC-SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVL 67
WFL L L + G+ + S+I+ G +C HSQPWQAAL + C G+LVH QWVL
Sbjct: 2 WFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVL 61
Query: 68 SAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN-----------D 116
+AAHC ++Y + LG H+L D E +Q V S S HP +N LL N D
Sbjct: 62 TAAHCISDNYQLWLGRHNL-FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 117 LMLIKLDESVSE-SDTIRSISIASQCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVV 173
LML++L E +D ++ + + ++ P G++CL SGWG + N P LQCV++ ++
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 174 SEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGV 233
+ C K + M C G KD+C GDSGGPL+C+G LQG+ S+G PCG
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 234 PGVYTNLCKFTEWIEKTV 251
P V + + +WIE T+
Sbjct: 241 PSVAVRVLSYVKWIEDTI 258
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 183 bits (465), Expect = 1e-46
Identities = 101/236 (42%), Positives = 140/236 (59%), Gaps = 8/236 (3%)
Query: 14 YLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF 73
+L+L V G L + +I NG +C +SQPWQ L L C GVL+ +WVL+AAHC
Sbjct: 6 FLLLCVLG-LSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCS 64
Query: 74 QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDESVSESDT 131
+ Y + LG HSL + + Q+ + SV HP Y + +DL L++L V + +
Sbjct: 65 GSRYWVRLGEHSL-SQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123
Query: 132 IRSISIASQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPS 189
++ + + + C TAG C VSGWG+ + R P +LQC+N+S+VS C +Y +
Sbjct: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183
Query: 190 MFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGK-APCGQVGVPGVYTNLCKFT 244
M CAGG Q D+C GDSGGPL+C G LQGLVS+G PCGQ G+PGVYT +C T
Sbjct: 184 MVCAGGVPGQ-DACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICNST 238
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 181 bits (459), Expect = 5e-46
Identities = 91/227 (40%), Positives = 134/227 (59%), Gaps = 5/227 (2%)
Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
+I+ G +C +S P+Q +L FC G L++ QWV+SA HC+++ + LG H++E
Sbjct: 23 KIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEV- 80
Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149
E Q + A+ +RHP+Y+R L ND+MLIKL + + +IS+ + P G CL
Sbjct: 81 LEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCL 140
Query: 150 VSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207
+SGWG A+ P LQC++ V+S+ C Y +MFC G KDSC GDS
Sbjct: 141 ISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDS 200
Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
GGP++CNG LQG+VS+G C Q PGVYT + + +WI+ T+ A+
Sbjct: 201 GGPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIKNTIAAN 246
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 177 bits (449), Expect = 8e-45
Identities = 95/246 (38%), Positives = 139/246 (56%), Gaps = 8/246 (3%)
Query: 14 YLILGVAGSLVS---GSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAA 70
+LIL G+ V+ +I+ G C +S P+Q +L + FC G L+ QWV+SAA
Sbjct: 4 FLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAA 62
Query: 71 HCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130
HC++ + LG H+++ E Q + A+ +RHP+YNR L ND+MLIKL +
Sbjct: 63 HCYKTRIQVRLGEHNIKV-LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINA 121
Query: 131 TIRSISIASQCPTAGNSCLVSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP 188
+ +IS+ + P AG CL+SGWG L P L+C++ V+++ C Y
Sbjct: 122 RVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITN 181
Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248
SMFC G KDSC DSGGP++CNG LQG+VS+G C PGVYT + + +WI+
Sbjct: 182 SMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIK 240
Query: 249 KTVQAS 254
T+ A+
Sbjct: 241 DTIAAN 246
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 176 bits (446), Expect = 2e-44
Identities = 86/230 (37%), Positives = 132/230 (57%), Gaps = 7/230 (3%)
Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
++ I E+C P+SQPWQA L LFC L+ +W+L+AAHC + + LG H L
Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80
Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLAND----LMLIKLDESVSESDTIRSISIASQCPTA 144
+ P Q+ + HP +N+ L AND +MLI+L S ++ ++++ C +
Sbjct: 81 WEGP-EQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSP 139
Query: 145 GNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202
G CL+SGWG +++ + P LQC N+S++ ++C Y SM CAG + S
Sbjct: 140 GMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGS 199
Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
C GDSGGPL+CNG L G+VS G PC + P VYT++C + +WI++ ++
Sbjct: 200 CQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIME 249
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 174 bits (442), Expect = 5e-44
Identities = 90/227 (39%), Positives = 131/227 (57%), Gaps = 5/227 (2%)
Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
+I+ G C +S P+Q +L + FC G L+ QWV+SAAHC++ + LG H+++
Sbjct: 80 KIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV- 137
Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149
E Q + A+ +RHP+YNR L ND+MLIKL + + +IS+ + P AG CL
Sbjct: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197
Query: 150 VSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207
+SGWG L P L+C++ V+++ C Y SMFC G KDSC DS
Sbjct: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257
Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
GGP++CNG LQG+VS+G C PGVYT + + +WI+ T+ A+
Sbjct: 258 GGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 171 bits (432), Expect = 7e-43
Identities = 89/227 (39%), Positives = 130/227 (57%), Gaps = 5/227 (2%)
Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
+I+ G C +S P+Q +L FC G L+ QWV+SA HC+++ + LG H++E
Sbjct: 23 KIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEV- 80
Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149
E Q + A+ +RHP+YN L ND++LIKL + + +IS+ + P AG L
Sbjct: 81 LEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESL 140
Query: 150 VSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207
+SGWG L + P LQC++ V+S+ C Y +MFC G KDSC GDS
Sbjct: 141 ISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDS 200
Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
GGP++ NG LQG+VS+G C Q PGVYT + + +WI+ T+ A+
Sbjct: 201 GGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAAN 246
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 152 bits (385), Expect = 2e-37
Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 13/231 (5%)
Query: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93
G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 106
Query: 94 SQMVEASLSVRHPEYNR---PLLA-----NDLMLIKLDESVSESDTIRSISIASQCPTAG 145
Q+ + SV HP+Y++ P+L +DLML+KL V +R++ + +C G
Sbjct: 107 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 166
Query: 146 NSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203
+ C V+GWG A R+ L C +++++S + C Y + +M CAG Q D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQ-DPC 225
Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 152 bits (385), Expect = 2e-37
Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 13/231 (5%)
Query: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93
G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 106
Query: 94 SQMVEASLSVRHPEYNR---PLLA-----NDLMLIKLDESVSESDTIRSISIASQCPTAG 145
Q+ + SV HP+Y++ P+L +DLML+KL V +R++ + +C G
Sbjct: 107 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 166
Query: 146 NSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203
+ C V+GWG A R+ L C +++++S + C Y + +M CAG Q D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQ-DPC 225
Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 152 bits (385), Expect = 2e-37
Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 13/231 (5%)
Query: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93
G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 106
Query: 94 SQMVEASLSVRHPEYNR---PLLA-----NDLMLIKLDESVSESDTIRSISIASQCPTAG 145
Q+ + SV HP+Y++ P+L +DLML+KL V +R++ + +C G
Sbjct: 107 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 166
Query: 146 NSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203
+ C V+GWG A R+ L C +++++S + C Y + +M CAG Q D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQ-DPC 225
Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|4885369 granzyme M precursor [Homo sapiens]
Length = 257
Score = 150 bits (378), Expect = 1e-36
Identities = 93/253 (36%), Positives = 134/253 (52%), Gaps = 17/253 (6%)
Query: 15 LILGVAGSLVSGSC--SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72
L++ G+L GS +QII G + PHS+P+ A+L C GVLVHP+WVL+AAHC
Sbjct: 8 LLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHC 67
Query: 73 FQN---SYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-PLLANDLMLIKLDESVSE 128
+ LGLH+L++ PG +++HP Y P L NDL L++LD V
Sbjct: 68 LAQRMAQLRLVLGLHTLDS---PGLTF-HIKAAIQHPRYKPVPALENDLALLQLDGKVKP 123
Query: 129 SDTIRSISIAS--QCPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVC--SKLYD 183
S TIR +++ S Q AG C ++GWGL GR+ VL+ +++ V+ +C S+ ++
Sbjct: 124 SRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWN 183
Query: 184 PLYHPSMFCAGGGHDQKDSCNGDSGGPLIC--NGYLQGLVSFGKAPCGQVGVPGVYTNLC 241
PSM C + C GDSGGPL+C L G++SF C + P V T +
Sbjct: 184 GSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVA 243
Query: 242 KFTEWIEKTVQAS 254
+ WI K S
Sbjct: 244 PYVSWIRKVTGRS 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,524,361
Number of Sequences: 37866
Number of extensions: 472776
Number of successful extensions: 1560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 939
Number of HSP's gapped (non-prelim): 216
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.