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Search of human proteins with 86198310
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
(303 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 607 e-174
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 209 3e-54
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 192 4e-49
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 170 2e-42
gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 166 2e-41
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 130 1e-30
gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] 129 4e-30
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 122 4e-28
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 115 6e-26
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 113 2e-25
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 113 2e-25
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 104 8e-23
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 103 2e-22
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 100 2e-21
gi|13899342 solute carrier [Homo sapiens] 97 2e-20
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 96 5e-20
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 94 1e-19
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 94 1e-19
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 93 3e-19
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 92 7e-19
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 91 1e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 91 1e-18
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 91 1e-18
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 90 3e-18
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 89 4e-18
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 89 5e-18
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 89 6e-18
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 89 6e-18
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 89 6e-18
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 89 6e-18
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 607 bits (1565), Expect = e-174
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYK 60
MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYK
Sbjct: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYK 60
Query: 61 GLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRL 120
GLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRL
Sbjct: 61 GLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRL 120
Query: 121 QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALG 180
QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALG
Sbjct: 121 QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALG 180
Query: 181 CEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYR 240
CEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYR
Sbjct: 181 CEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYR 240
Query: 241 AEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQP 300
AEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQP
Sbjct: 241 AEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQP 300
Query: 301 SSL 303
SSL
Sbjct: 301 SSL 303
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 209 bits (531), Expect = 3e-54
Identities = 119/288 (41%), Positives = 166/288 (57%), Gaps = 22/288 (7%)
Query: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
+F+AG G G+++GHPFDTVKVRLQ Q+ YRG + C I + ES+LG +KG+
Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQTT----YRGIVDCMVKIYRHESLLGFFKGMS 60
Query: 64 SPLMGLTFINALVFGVQGNTLRAL---GHD-------SPLNQFLAGAAAGAIQCVICCPM 113
P+ + +N+++FGV NTL L H S ++ FLAG G +Q P
Sbjct: 61 FPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPF 120
Query: 114 ELAKTRLQ------LQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
+L K RLQ Q P Y+G + C A I+ EG RG+ RG + LR+TP+ G+
Sbjct: 121 DLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRDTPTVGI 180
Query: 168 YFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPR 227
YF+TY+ L R E G +L+AGG +GI SW++ P+D++KSR+Q DGLR
Sbjct: 181 YFITYEGLCRQYTPE-GQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRV- 238
Query: 228 YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTY 275
Y+G+LDC+ S R EG VF RG+ RAFPVNA TF + +L +
Sbjct: 239 YQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRW 286
Score = 89.7 bits (221), Expect = 3e-18
Identities = 63/189 (33%), Positives = 90/189 (47%), Gaps = 16/189 (8%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEK-------PQYRGTLHCFKSIIKQESVLG 57
FLAGC GG PFD +KVRLQ Q+ + P+Y+G +HC SI ++E G
Sbjct: 103 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 162
Query: 58 LYKGL------GSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICC 111
L++G +P +G+ FI G+ + S +AG AG V
Sbjct: 163 LFRGAWALTLRDTPTVGIYFIT--YEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAAT 220
Query: 112 PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLT 171
P+++ K+R+Q+ D R Y+G LDC+ EGL RG+ R P V FL+
Sbjct: 221 PLDMIKSRMQM-DGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLS 279
Query: 172 YDALTRALG 180
Y+ L R G
Sbjct: 280 YEYLLRWWG 288
Score = 81.3 bits (199), Expect = 1e-15
Identities = 69/213 (32%), Positives = 92/213 (43%), Gaps = 20/213 (9%)
Query: 92 PLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVN 151
P+ +F+AG +GA+ V+ P + K RLQ Q TY+G +DC+ +IY HE L G
Sbjct: 2 PVEEFVAGWISGALGLVLGHPFDTVKVRLQTQT-----TYRGIVDCMVKIYRHESLLGFF 56
Query: 152 RGM----VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPK---LLLAGGTSGIVSW 204
+GM S + + FGVY T LT E R P + LAG T G +
Sbjct: 57 KGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQER--RAQPPSYMHIFLAGCTGGFLQA 114
Query: 205 LSTYPVDVVKSRLQ------ADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258
P D++K RLQ A PRY+G + C +R EG R RG + LR
Sbjct: 115 YCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLRD 174
Query: 259 FPVNAATFATVTVVLTYARGEEAGPEGEAVPAA 291
P F T + E P V A
Sbjct: 175 TPTVGIYFITYEGLCRQYTPEGQNPSSATVLVA 207
>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
Length = 308
Score = 192 bits (487), Expect = 4e-49
Identities = 118/310 (38%), Positives = 164/310 (52%), Gaps = 39/310 (12%)
Query: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGL 62
+DF+AG GGV GV VG+P DTVKVR+Q + P+Y G HC + +E V G Y+GL
Sbjct: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTE----PKYTGIWHCVRDTYHRERVWGFYRGL 56
Query: 63 GSPLMGLTFINALVFGVQGNTLR---ALGHDSP------LNQFLAGAAAGAIQCVICCPM 113
P+ ++ ++++ FG + L L + +P + L+G A+G ++ + P
Sbjct: 57 SLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPT 116
Query: 114 ELAKTRLQLQD-------------------------AGPARTYKGSLDCLAQIYGHEGLR 148
E+AK RLQ Q A P Y+G L CLA + EGL
Sbjct: 117 EVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLC 176
Query: 149 GVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTY 208
G+ +G + +LR+ SF YFL+Y L L R VP +L+AGG +G+++W
Sbjct: 177 GLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVAT 236
Query: 209 PVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
P+DV+KSRLQADG +G RYRG+L C+ S R EG RV +GL RAFPVN F
Sbjct: 237 PMDVIKSRLQADG-QGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVA 295
Query: 269 VTVVLTYARG 278
VL ARG
Sbjct: 296 YEAVLRLARG 305
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 170 bits (430), Expect = 2e-42
Identities = 107/285 (37%), Positives = 154/285 (54%), Gaps = 17/285 (5%)
Query: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQSV----EKPQYRGTLHCFKSIIKQESVLGLY 59
+ LAG GGV V VGHP DTVKVRLQ Q + P Y GT CF+ + +E + GLY
Sbjct: 13 NLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLY 72
Query: 60 KGLGSPLMGLTFINALVF---GVQGNTLRALGHDSPLNQ---FLAGAAAGAIQCVICCPM 113
+G+ +P++G+T + A+ F G+ G L+ + L+ F AG +G I P
Sbjct: 73 RGMAAPIIGVTPMFAVCFFGFGL-GKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPG 131
Query: 114 ELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYD 173
E K LQ+Q + Y G+LDC ++Y G+RG+ +G V TL+R+ P+ G+YF+TY+
Sbjct: 132 ERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYE 191
Query: 174 ALTRALGCEPGDR---LLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRG 230
L E G R L P++L+AGG +GI +W P DV+KSR Q P G
Sbjct: 192 WLKNIFTPE-GKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYP--NG 248
Query: 231 ILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTY 275
D + + R EG +G + ++RAFP NAA F V + +
Sbjct: 249 FRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293
Score = 92.4 bits (228), Expect = 4e-19
Identities = 58/181 (32%), Positives = 81/181 (44%), Gaps = 3/181 (1%)
Query: 91 SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDA---GPARTYKGSLDCLAQIYGHEGL 147
SPL LAG G + P++ K RLQ Q G Y G+ DC + EG+
Sbjct: 9 SPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGI 68
Query: 148 RGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLST 207
G+ RGM + ++ TP F V F + + P D L P+L AG SG+ +
Sbjct: 69 TGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIM 128
Query: 208 YPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFA 267
P + +K LQ G +Y G LDC + Y+ G R +G TL+R P + F
Sbjct: 129 TPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFM 188
Query: 268 T 268
T
Sbjct: 189 T 189
>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
sapiens]
Length = 246
Score = 166 bits (421), Expect = 2e-41
Identities = 97/243 (39%), Positives = 137/243 (56%), Gaps = 18/243 (7%)
Query: 49 IIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRAL---GHD-------SPLNQFLA 98
I + ES+LG +KG+ P+ + +N+++FGV NTL L H S ++ FLA
Sbjct: 4 IYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLA 63
Query: 99 GAAAGAIQCVICCPMELAKTRLQ------LQDAGPARTYKGSLDCLAQIYGHEGLRGVNR 152
G G +Q P +L K RLQ Q P Y+G + C A I+ EG RG+ R
Sbjct: 64 GCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFR 123
Query: 153 GMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDV 212
G + LR+TP+ G+YF+TY+ L R E G +L+AGG +GI SW++ P+D+
Sbjct: 124 GAWALTLRDTPTVGIYFITYEGLCRQYTPE-GQNPSSATVLVAGGFAGIASWVAATPLDM 182
Query: 213 VKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVV 272
+KSR+Q DGLR Y+G+LDC+ S R EG VF RG+ RAFPVNA TF + +
Sbjct: 183 IKSRMQMDGLRRRV-YQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 241
Query: 273 LTY 275
L +
Sbjct: 242 LRW 244
Score = 89.7 bits (221), Expect = 3e-18
Identities = 63/189 (33%), Positives = 90/189 (47%), Gaps = 16/189 (8%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEK-------PQYRGTLHCFKSIIKQESVLG 57
FLAGC GG PFD +KVRLQ Q+ + P+Y+G +HC SI ++E G
Sbjct: 61 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120
Query: 58 LYKGL------GSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICC 111
L++G +P +G+ FI G+ + S +AG AG V
Sbjct: 121 LFRGAWALTLRDTPTVGIYFIT--YEGLCRQYTPEGQNPSSATVLVAGGFAGIASWVAAT 178
Query: 112 PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLT 171
P+++ K+R+Q+ D R Y+G LDC+ EGL RG+ R P V FL+
Sbjct: 179 PLDMIKSRMQM-DGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLS 237
Query: 172 YDALTRALG 180
Y+ L R G
Sbjct: 238 YEYLLRWWG 246
Score = 50.1 bits (118), Expect = 2e-06
Identities = 51/167 (30%), Positives = 65/167 (38%), Gaps = 15/167 (8%)
Query: 138 LAQIYGHEGLRGVNRGM----VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPK-- 191
+ +IY HE L G +GM S + + FGVY T LT E R P
Sbjct: 1 MVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQER--RAQPPSYM 58
Query: 192 -LLLAGGTSGIVSWLSTYPVDVVKSRLQ------ADGLRGAPRYRGILDCVHQSYRAEGW 244
+ LAG T G + P D++K RLQ A PRY+G + C +R EG
Sbjct: 59 HIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGP 118
Query: 245 RVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAA 291
R RG + LR P F T + E P V A
Sbjct: 119 RGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVA 165
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 130 bits (327), Expect = 1e-30
Identities = 96/281 (34%), Positives = 136/281 (48%), Gaps = 22/281 (7%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61
A+D AG AGG A VL G PFDT+KV++Q Y+G CF Q + G YKG
Sbjct: 10 AIDLTAGAAGGTACVLTGQPFDTIKVKMQ---TFPDLYKGLTDCFLKTYAQVGLRGFYKG 66
Query: 62 LGSPLMGLTFINALVFGVQG----NTLRALGHD-----SPLNQFLAGAAAGAIQCVICCP 112
G LM N+++F G + G D S L AG+ A A + CP
Sbjct: 67 TGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCP 126
Query: 113 MELAKTRLQ----LQDAGP-ARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
EL K RLQ ++ +G A+++ + I +G G G+ STLL+E P +
Sbjct: 127 TELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFF 186
Query: 168 YFLTYDALTRAL--GCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGA 225
+F Y+ L+R+ D L L+L+GG +GI WL +PVD +KSR+Q + G
Sbjct: 187 FFGGYE-LSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYG- 244
Query: 226 PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
+ G + + R EG GL +T++RA P N A F
Sbjct: 245 -KQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALF 284
>gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]
Length = 301
Score = 129 bits (323), Expect = 4e-30
Identities = 96/281 (34%), Positives = 133/281 (47%), Gaps = 22/281 (7%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61
A+D AG AGG A VL G PFDT+KV++Q YRG C Q G YKG
Sbjct: 10 AIDLTAGAAGGTACVLTGQPFDTMKVKMQTFP---DLYRGLTDCCLKTYSQVGFRGFYKG 66
Query: 62 LGSPLMGLTFINALVFGVQGNTLRAL----GHD-----SPLNQFLAGAAAGAIQCVICCP 112
L+ N+++F G + + G D S L AG+ A A ++ CP
Sbjct: 67 TSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCP 126
Query: 113 MELAKTRLQ----LQDAGP-ARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
EL K RLQ ++ +G A++ + I +G G G+ STLLRE P +
Sbjct: 127 TELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFF 186
Query: 168 YFLTYDALTRALGCE--PGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGA 225
+F Y+ L+R+ D L L+L+GG GI WL+ YPVD +KSR+Q + G
Sbjct: 187 FFGGYE-LSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSG- 244
Query: 226 PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
+ G + + EG GL T++RAFP N A F
Sbjct: 245 -KQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALF 284
Score = 48.5 bits (114), Expect = 7e-06
Identities = 47/183 (25%), Positives = 75/183 (40%), Gaps = 22/183 (12%)
Query: 7 AGCAGGVAGVLVGHPFDTVKVRLQVQ-------SVEKPQYRGTLHCFKSIIKQESVLGLY 59
AG LV P + VK RLQ + K Q KSI++++ LG Y
Sbjct: 112 AGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQ-NTVWSVIKSILRKDGPLGFY 170
Query: 60 KGLGSPLM----GLTFIN-----ALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVIC 110
GL S L+ G F + F G + LG P+ L+G G +
Sbjct: 171 HGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELG---PVPLMLSGGVGGICLWLAV 227
Query: 111 CPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFL 170
P++ K+R+Q+ + G + + +EG+ + G+ T++R P+ G FL
Sbjct: 228 YPVDCIKSRIQVLSMSGKQA--GFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFL 285
Query: 171 TYD 173
Y+
Sbjct: 286 AYE 288
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 122 bits (306), Expect = 4e-28
Identities = 90/278 (32%), Positives = 136/278 (48%), Gaps = 20/278 (7%)
Query: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQS--VEKPQYRGTLHCFKSIIKQESVLGLYKG 61
+ +AG +GGV L HP D VK+R V +P+Y G LHC +I K + + GLY+G
Sbjct: 25 NLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQG 84
Query: 62 LGSPLMGLTFINALVF----GVQGNTLRALGHDSPLNQFLAGAA-AGAIQCVICCPMELA 116
+ + G L F ++ ++L AA AGA+ I P+ +
Sbjct: 85 VTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVT 144
Query: 117 KTRLQLQ-DA---GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172
KTRL LQ DA P R YKG D L +IY +EG+RG+ +G V L T + F+ Y
Sbjct: 145 KTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAY 203
Query: 173 DAL----TRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRY 228
+ L + + P +L + + S I + +TYP VV++RLQ + Y
Sbjct: 204 ELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHM----FY 259
Query: 229 RGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
G++D + +++R EG F +G+A L+R P TF
Sbjct: 260 SGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITF 297
Score = 56.6 bits (135), Expect = 3e-08
Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 24/195 (12%)
Query: 2 ALDFLAGCA-GGVAGVLVGHPFDTVKVRLQVQS---VEKP--QYRGTLHCFKSIIKQESV 55
A ++L A G + + +P K RL +Q V P QY+G I K E V
Sbjct: 120 ATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGV 179
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLN----------QFLAGAAAGAI 105
GLYKG L G T AL F L L ++ +N ++++ AA I
Sbjct: 180 RGLYKGFVPGLFG-TSHGALQF--MAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKI 236
Query: 106 QCVICC-PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPS 164
V P ++ + RLQ Q Y G +D + + + EG+ G +G+ L+R TP+
Sbjct: 237 FAVAATYPYQVVRARLQDQHM----FYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPA 292
Query: 165 FGVYFLTYDALTRAL 179
+ F+ Y+ ++ L
Sbjct: 293 CCITFVVYENVSHFL 307
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 115 bits (287), Expect = 6e-26
Identities = 88/312 (28%), Positives = 132/312 (42%), Gaps = 23/312 (7%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56
A F G G G +P D VK R+Q Q V + Y+ + CFK +++ E
Sbjct: 327 AYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFF 386
Query: 57 GLYKGLGSPLMGLTFINALVFGV----QGNTLRALGHDSPLNQFLAGAAAGAIQCVICCP 112
GLY+GL L+G+ A+ V + R G + LAG AG Q + P
Sbjct: 387 GLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNP 446
Query: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172
+E+ K RLQ+ +L+ L + G+ G+ +G + LR+ P +YF Y
Sbjct: 447 LEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSAIYFPVY 502
Query: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232
L E G + LL AG +G+ + P DV+K+RLQ G Y G++
Sbjct: 503 AHCKLLLADENG-HVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVI 561
Query: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTY---------ARGEEAGP 283
DC + R EG F +G A+ + R+ P T T ++ + G E P
Sbjct: 562 DCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAGSEPTP 621
Query: 284 EGEAVPAAPAGP 295
+ PA P
Sbjct: 622 KSRIADLPPANP 633
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 113 bits (282), Expect = 2e-25
Identities = 83/276 (30%), Positives = 123/276 (44%), Gaps = 14/276 (5%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56
A F G G G +P D VK R+Q Q V + Y+ + CFK +++ E
Sbjct: 329 AYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFF 388
Query: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS---PLN-QFLAGAAAGAIQCVICCP 112
GLY+GL L+G+ A+ V H PL + LAG AG Q + P
Sbjct: 389 GLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNP 448
Query: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172
+E+ K RLQ+ AG T G + G G+ +G + LR+ P +YF Y
Sbjct: 449 LEIVKIRLQV--AGEITT--GPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 504
Query: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232
+ + E G ++ LLLAG +G+ + P DV+K+RLQ G Y G++
Sbjct: 505 AHVKASFANEDG-QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 563
Query: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
DC + R EG + +G + + R+ P T T
Sbjct: 564 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 599
Score = 82.0 bits (201), Expect = 6e-16
Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 9/182 (4%)
Query: 1 MALDFLAG-CAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLY 59
+A + LAG CAGG + V+ +P + VK+RLQV R + S+++ G+Y
Sbjct: 428 LAAEILAGGCAGG-SQVIFTNPLEIVKIRLQVAGEITTGPRVSA---LSVVRDLGFFGIY 483
Query: 60 KGLGSPLMGLTFINALVFG----VQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMEL 115
KG + + +A+ F V+ + G SP + LAGA AG + P ++
Sbjct: 484 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 543
Query: 116 AKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDAL 175
KTRLQ+ TY G +DC +I EG + + +G + + R +P FGV LTY+ L
Sbjct: 544 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
Query: 176 TR 177
R
Sbjct: 604 QR 605
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 113 bits (282), Expect = 2e-25
Identities = 83/276 (30%), Positives = 123/276 (44%), Gaps = 14/276 (5%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----VEKPQYRGTLHCFKSIIKQESVL 56
A F G G G +P D VK R+Q Q V + Y+ + CFK +++ E
Sbjct: 330 AYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFF 389
Query: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS---PLN-QFLAGAAAGAIQCVICCP 112
GLY+GL L+G+ A+ V H PL + LAG AG Q + P
Sbjct: 390 GLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNP 449
Query: 113 MELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTY 172
+E+ K RLQ+ AG T G + G G+ +G + LR+ P +YF Y
Sbjct: 450 LEIVKIRLQV--AGEITT--GPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 505
Query: 173 DALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGIL 232
+ + E G ++ LLLAG +G+ + P DV+K+RLQ G Y G++
Sbjct: 506 AHVKASFANEDG-QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 564
Query: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
DC + R EG + +G + + R+ P T T
Sbjct: 565 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLT 600
Score = 82.0 bits (201), Expect = 6e-16
Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 9/182 (4%)
Query: 1 MALDFLAG-CAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLY 59
+A + LAG CAGG + V+ +P + VK+RLQV R + S+++ G+Y
Sbjct: 429 LAAEILAGGCAGG-SQVIFTNPLEIVKIRLQVAGEITTGPRVSA---LSVVRDLGFFGIY 484
Query: 60 KGLGSPLMGLTFINALVFG----VQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMEL 115
KG + + +A+ F V+ + G SP + LAGA AG + P ++
Sbjct: 485 KGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADV 544
Query: 116 AKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDAL 175
KTRLQ+ TY G +DC +I EG + + +G + + R +P FGV LTY+ L
Sbjct: 545 IKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604
Query: 176 TR 177
R
Sbjct: 605 QR 606
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 104 bits (260), Expect = 8e-23
Identities = 86/309 (27%), Positives = 135/309 (43%), Gaps = 43/309 (13%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSV-----------------EKPQYRGTLHCFK 47
F GC GG G ++ P + VK RLQ SV + G LHC K
Sbjct: 11 FAGGC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 48 SIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGH----DSPLNQFLAGAAAG 103
I+++E L++GLG L+G+ A+ F N L DS ++ A AG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 104 AIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTL--LRE 161
P+ L KTRLQL G+ +C+ ++Y +GL+G RGM ++ + E
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
Query: 162 TPSFGVYFLTYDALTRAL------GCEPGDRLLVPK------LLLAGGTSGIVSWLSTYP 209
T ++F+ Y+++ + L D V + ++LA TS + YP
Sbjct: 190 TV---IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP 246
Query: 210 VDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATV 269
+VV++RL+ +G +YR + + EG+ RGL + L+R P A AT
Sbjct: 247 HEVVRTRLREEG----TKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 302
Query: 270 TVVLTYARG 278
+V+ G
Sbjct: 303 ELVVYLLNG 311
Score = 72.8 bits (177), Expect = 4e-13
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQ---------------LQDAGPARTYK-GSLD 136
L AG G + ++ CP+E+ KTRLQ + A R G L
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
Query: 137 CLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAG 196
CL I EG R + RG+ L+ PS +YF Y L + D +++
Sbjct: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN-DVFDPDSTQVHMISA 125
Query: 197 GTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLAST 254
+G + +T P+ ++K+RLQ D R G +CV + Y+ +G + F RG++++
Sbjct: 126 AMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS 183
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 103 bits (257), Expect = 2e-22
Identities = 78/258 (30%), Positives = 125/258 (48%), Gaps = 13/258 (5%)
Query: 10 AGGVAG---VLVGHPFDTVKVRLQV-QSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSP 65
AGG+AG + + P + VK +LQ+ + P+YRG C + ++ VLGLY+GL S
Sbjct: 31 AGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSL 90
Query: 66 LMGLTFINALVFGV---QGNTLR-ALGHDSPLNQFLAGAAAGAIQC-VICCPMELAKTRL 120
L G A+ FG+ N +R A G L G AG + V+ CPME K +
Sbjct: 91 LYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKF 150
Query: 121 QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALG 180
P Y+G + +I +GL+G +G+ +T+L++ + + F +L
Sbjct: 151 IHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYR 210
Query: 181 CEPGDRLLVPKLL-LAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSY 239
+ ++ + P + + G +G S P+DV+K+R+Q GL A +YR DC Q
Sbjct: 211 GDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQ--GLE-AHKYRNTWDCGLQIL 267
Query: 240 RAEGWRVFTRGLASTLLR 257
+ EG + F +G L R
Sbjct: 268 KKEGLKAFYKGTVPRLGR 285
Score = 78.2 bits (191), Expect = 8e-15
Identities = 56/189 (29%), Positives = 89/189 (47%), Gaps = 2/189 (1%)
Query: 92 PLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVN 151
P LAG AG I+ I P E KT+LQL + Y+G DC+ Q G+ G+
Sbjct: 25 PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLY 84
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIV-SWLSTYPV 210
RG+ S L P V F ++ L+ + G RL + LL G +G+ + + P+
Sbjct: 85 RGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG-RLDSTRGLLCGLGAGVAEAVVVVCPM 143
Query: 211 DVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVT 270
+ +K + D P+YRG V + R +G + +GL +T+L+ A F +T
Sbjct: 144 ETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMT 203
Query: 271 VVLTYARGE 279
+ + RG+
Sbjct: 204 SLRNWYRGD 212
Score = 76.3 bits (186), Expect = 3e-14
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Query: 6 LAGCAGGVA-GVLVGHPFDTVKVR-LQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
L G GVA V+V P +T+KV+ + Q+ P+YRG H + I++++ + G Y+GL
Sbjct: 126 LCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLT 185
Query: 64 SPLMGLTFINALVFGVQG---NTLRALGHDSPLNQFLAG---AAAGAIQCVICCPMELAK 117
+ ++ A+ F V N R + P+N + G A AGA P+++ K
Sbjct: 186 ATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIK 245
Query: 118 TRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTR 177
TR+Q +A Y+ + DC QI EGL+ +G V L R + F+ YD + +
Sbjct: 246 TRMQGLEA---HKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVK 302
Query: 178 AL 179
L
Sbjct: 303 LL 304
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 100 bits (248), Expect = 2e-21
Identities = 86/309 (27%), Positives = 134/309 (43%), Gaps = 44/309 (14%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSV-----------------EKPQYRGTLHCFK 47
F GC GG G ++ P + VK RLQ SV + G LHC K
Sbjct: 11 FAGGC-GGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 48 SIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGH----DSPLNQFLAGAAAG 103
I+++E L++GLG L+G+ A+ F N L DS ++ A AG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 104 AIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTL--LRE 161
P+ L KTRLQL G+ +C+ ++Y +GL+G RGM ++ + E
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
Query: 162 TPSFGVYFLTYDALTRAL------GCEPGDRLLVPK------LLLAGGTSGIVSWLSTYP 209
T ++F+ Y+++ + L D V + ++LA TS + YP
Sbjct: 190 TV---IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP 246
Query: 210 VDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATV 269
VV++RL+ +G +YR + + EG+ RGL + L+R P A AT
Sbjct: 247 -HVVRTRLREEG----TKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATY 301
Query: 270 TVVLTYARG 278
+V+ G
Sbjct: 302 ELVVYLLNG 310
Score = 72.8 bits (177), Expect = 4e-13
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 17/178 (9%)
Query: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQ---------------LQDAGPARTYK-GSLD 136
L AG G + ++ CP+E+ KTRLQ + A R G L
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLH 66
Query: 137 CLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAG 196
CL I EG R + RG+ L+ PS +YF Y L + D +++
Sbjct: 67 CLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN-DVFDPDSTQVHMISA 125
Query: 197 GTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLAST 254
+G + +T P+ ++K+RLQ D R G +CV + Y+ +G + F RG++++
Sbjct: 126 AMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSAS 183
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 97.1 bits (240), Expect = 2e-20
Identities = 83/284 (29%), Positives = 124/284 (43%), Gaps = 34/284 (11%)
Query: 8 GCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLM 67
G G+ GV P D K RLQ Q K Y+G + C + E G+Y+G L
Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQH-GKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLT 73
Query: 68 GLTFINALVFGVQGNTLRALGHDSPLN----QFLAGAAAGAIQCVICCPMELAKTRLQLQ 123
+T A+ R L D + LAG AG Q V+ CPME+ K +QLQ
Sbjct: 74 LVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK--IQLQ 131
Query: 124 DAG--------------PARTY---------KGSLDCLA-QIYGHEGLRGVNRGMVSTLL 159
DAG +R+Y + S +A ++ +GL G+ RG+ +TLL
Sbjct: 132 DAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLL 191
Query: 160 RETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQA 219
R+ P +YF + L E + ++G +G ++ ++ P+DV+K+R+Q
Sbjct: 192 RDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQT 251
Query: 220 --DGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPV 261
GL G Y GI DC + + EG F +G L P+
Sbjct: 252 LKKGL-GEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPL 294
Score = 61.6 bits (148), Expect = 8e-10
Identities = 52/204 (25%), Positives = 89/204 (43%), Gaps = 35/204 (17%)
Query: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQ--------------VQSVEKPQYRGTLHCF 46
+ ++ LAGC G+ V+V P + +K++LQ S + G+
Sbjct: 102 LKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTH 161
Query: 47 K---------SIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHD------S 91
+ +++ + + GLY+GLG+ L+ + + F + N L LG + S
Sbjct: 162 RRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFAN-LNNLGFNELAGKAS 220
Query: 92 PLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPAR-TYKGSLDCLAQIYGHEGLRGV 150
+ F++G AG+I V P+++ KTR+Q G Y G DC +++ EG
Sbjct: 221 FAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAF 280
Query: 151 NRGMVSTLLRETPSF----GVYFL 170
+G L P F GVYF+
Sbjct: 281 MKGAGCRALVIAPLFGIAQGVYFI 304
Score = 61.2 bits (147), Expect = 1e-09
Identities = 57/195 (29%), Positives = 83/195 (42%), Gaps = 27/195 (13%)
Query: 95 QFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGM 154
+ + G AG + P++LAKTRLQ Q YKG +DCL + EG G+ RG
Sbjct: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHG--KAMYKGMIDCLMKTARAEGFFGMYRGA 68
Query: 155 VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVK 214
L TP + D R L E G + + +LAG +G+ + T P++++K
Sbjct: 69 AVNLTLVTPEKAIKLAANDFFRRLL-MEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLK 127
Query: 215 SRLQADGLRGAPRYRGILDC--VHQSY---------------------RAEGWRVFTRGL 251
+LQ D R A ++G +SY R +G RGL
Sbjct: 128 IQLQ-DAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGL 186
Query: 252 ASTLLRAFPVNAATF 266
+TLLR P + F
Sbjct: 187 GATLLRDIPFSIIYF 201
Score = 50.8 bits (120), Expect = 1e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 187 LLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRV 246
L + L+ GG +G+V +P+D+ K+RLQ G Y+G++DC+ ++ RAEG+
Sbjct: 6 LSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ--HGKAMYKGMIDCLMKTARAEGFFG 63
Query: 247 FTRGLASTLLRAFPVNAATFA 267
RG A L P A A
Sbjct: 64 MYRGAAVNLTLVTPEKAIKLA 84
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 95.5 bits (236), Expect = 5e-20
Identities = 83/274 (30%), Positives = 126/274 (45%), Gaps = 20/274 (7%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKP-----QYRGTLHCFKSIIKQESVL 56
A DFLAG P + VK+ LQVQ K QY+G + C I K++ VL
Sbjct: 9 AKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVL 68
Query: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRA-LGHDSPLNQF--------LAGAAAGAIQC 107
++G + ++ AL F + + LG QF +G AAGA
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSL 128
Query: 108 VICCPMELAKTRL--QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSF 165
P++ A+TRL + AG R ++G DCL +IY +G++G+ +G ++
Sbjct: 129 CFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
Query: 166 GVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRG 224
YF YD L +P + +V ++A T V+ L++YP D V+ R+ G +G
Sbjct: 189 AAYFGIYDTAKGMLP-DPKNTHIVISWMIAQ-TVTAVAGLTSYPFDTVRRRMMMQSGRKG 246
Query: 225 AP-RYRGILDCVHQSYRAEGWRVFTRGLASTLLR 257
Y G LDC + R EG + F +G S +LR
Sbjct: 247 TDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
Score = 72.0 bits (175), Expect = 6e-13
Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 10/181 (5%)
Query: 96 FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPART----YKGSLDCLAQIYGHEGLRGVN 151
FLAG A AI P+E K LQ+Q A T YKG +DC+ +I +G+
Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRAL--GCEPGDR--LLVPKLLLAGGTSGIVSWLST 207
RG ++ ++R P+ + F D + G + + L L +GG +G S
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFV 131
Query: 208 YPVDVVKSRLQAD-GLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAAT 265
YP+D ++RL AD G GA R +RG+ DC+ + Y+++G + +G ++ AA
Sbjct: 132 YPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAY 191
Query: 266 F 266
F
Sbjct: 192 F 192
Score = 45.8 bits (107), Expect = 5e-05
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADG----LRGAPRYRGILDCVHQSYRAEGWRV 246
K LAGG + +S + P++ VK LQ + +Y+GI+DCV + + +G
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 247 FTRGLASTLLRAFPVNAATFA 267
F RG + ++R FP A FA
Sbjct: 70 FWRGNLANVIRYFPTQALNFA 90
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 94.0 bits (232), Expect = 1e-19
Identities = 80/276 (28%), Positives = 124/276 (44%), Gaps = 24/276 (8%)
Query: 11 GGVAGVLVGH---PFDTVKVRLQVQS------VEKPQYRGTLHCFKSIIKQESVLGLYKG 61
GG+A ++ P D K RLQVQ ++ +YRG H I K+E VL LY G
Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106
Query: 62 LGSPLMGLTFINALVFGVQGNTLR----ALGHDSPLNQFLAGAAAGAIQCVICCPMELAK 117
+ L+ + G+ + R L ++ L + G +G I I P ++ K
Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLK 166
Query: 118 TRLQLQDAGPARTYKGS-LDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALT 176
R+Q Q + ++GS + IY EG RG+ RG+V T R GV YD
Sbjct: 167 IRMQAQGS----LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITK 222
Query: 177 R--ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRL--QADGLRGAPRYRGIL 232
+ L GD +L ++ T G+ L++ PVDVV++R+ Q + Y+G +
Sbjct: 223 KHLILSGMMGDTILTH--FVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTV 280
Query: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
D + + ++ EG+ +G LR P N F T
Sbjct: 281 DGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFIT 316
Score = 67.4 bits (163), Expect = 1e-11
Identities = 43/190 (22%), Positives = 88/190 (46%), Gaps = 21/190 (11%)
Query: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----------VEKPQYRGTLHCFKSI 49
+ ++ + G GV + +P D +K+R+Q Q ++ Q GT ++ +
Sbjct: 141 LLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGV 200
Query: 50 IKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVI 109
+ + G+ P+ +T + ++ G+ G+T+ L F++ G +
Sbjct: 201 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTI--------LTHFVSSFTCGLAGALA 252
Query: 110 CCPMELAKTRLQLQDA--GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
P+++ +TR+ Q A G YKG++D + +++ HEG + +G LR P +
Sbjct: 253 SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNII 312
Query: 168 YFLTYDALTR 177
+F+TY+ L R
Sbjct: 313 FFITYEQLKR 322
Score = 57.8 bits (138), Expect = 1e-08
Identities = 59/212 (27%), Positives = 93/212 (43%), Gaps = 14/212 (6%)
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHD-SPLN--QFLAGAAAGAIQCVICCP 112
+G++ G+ + + F A V + H+ S LN F+ G A + P
Sbjct: 1 MGIFPGIILIFLRVKFATAAVIVSGHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFP 60
Query: 113 MELAKTRLQLQDAG-PAR----TYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
++L KTRLQ+Q AR Y+G L +I EG+ + G+ LLR+ +
Sbjct: 61 VDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTI 120
Query: 168 YFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPR 227
Y +L R D L+ ++ G SG++S P DV+K R+QA G
Sbjct: 121 KIGIYQSLKRLFVERLEDETLLIN-MICGVVSGVISSTIANPTDVLKIRMQAQG----SL 175
Query: 228 YRG-ILDCVHQSYRAEGWRVFTRGLASTLLRA 258
++G ++ Y+ EG R RG+ T RA
Sbjct: 176 FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207
Score = 40.8 bits (94), Expect = 0.001
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPR-----YRGILDCVHQSYRAEGWR 245
K + GG + IV+ T+PVD+ K+RLQ G R YRG+ + + + EG
Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101
Query: 246 VFTRGLASTLLRAFPVNAATFATVTV 271
G+A LLR A++ T+ +
Sbjct: 102 ALYSGIAPALLR-----QASYGTIKI 122
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 94.0 bits (232), Expect = 1e-19
Identities = 80/276 (28%), Positives = 124/276 (44%), Gaps = 24/276 (8%)
Query: 11 GGVAGVLVGH---PFDTVKVRLQVQS------VEKPQYRGTLHCFKSIIKQESVLGLYKG 61
GG+A ++ P D K RLQVQ ++ +YRG H I K+E VL LY G
Sbjct: 44 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 103
Query: 62 LGSPLMGLTFINALVFGVQGNTLR----ALGHDSPLNQFLAGAAAGAIQCVICCPMELAK 117
+ L+ + G+ + R L ++ L + G +G I I P ++ K
Sbjct: 104 IAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLK 163
Query: 118 TRLQLQDAGPARTYKGS-LDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALT 176
R+Q Q + ++GS + IY EG RG+ RG+V T R GV YD
Sbjct: 164 IRMQAQGS----LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITK 219
Query: 177 R--ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRL--QADGLRGAPRYRGIL 232
+ L GD +L ++ T G+ L++ PVDVV++R+ Q + Y+G +
Sbjct: 220 KHLILSGMMGDTILTH--FVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTV 277
Query: 233 DCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
D + + ++ EG+ +G LR P N F T
Sbjct: 278 DGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFIT 313
Score = 67.4 bits (163), Expect = 1e-11
Identities = 43/190 (22%), Positives = 88/190 (46%), Gaps = 21/190 (11%)
Query: 1 MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-----------VEKPQYRGTLHCFKSI 49
+ ++ + G GV + +P D +K+R+Q Q ++ Q GT ++ +
Sbjct: 138 LLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGV 197
Query: 50 IKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVI 109
+ + G+ P+ +T + ++ G+ G+T+ L F++ G +
Sbjct: 198 VPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTI--------LTHFVSSFTCGLAGALA 249
Query: 110 CCPMELAKTRLQLQDA--GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGV 167
P+++ +TR+ Q A G YKG++D + +++ HEG + +G LR P +
Sbjct: 250 SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNII 309
Query: 168 YFLTYDALTR 177
+F+TY+ L R
Sbjct: 310 FFITYEQLKR 319
Score = 58.2 bits (139), Expect = 9e-09
Identities = 56/209 (26%), Positives = 90/209 (43%), Gaps = 11/209 (5%)
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMEL 115
+G++ G+ + + F A V + T+ F+ G A + P++L
Sbjct: 1 MGIFPGIILIFLRVKFATAAVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDL 60
Query: 116 AKTRLQLQDAG-PAR----TYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFL 170
KTRLQ+Q AR Y+G L +I EG+ + G+ LLR+ +
Sbjct: 61 TKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIG 120
Query: 171 TYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRG 230
Y +L R D L+ ++ G SG++S P DV+K R+QA G ++G
Sbjct: 121 IYQSLKRLFVERLEDETLLIN-MICGVVSGVISSTIANPTDVLKIRMQAQG----SLFQG 175
Query: 231 -ILDCVHQSYRAEGWRVFTRGLASTLLRA 258
++ Y+ EG R RG+ T RA
Sbjct: 176 SMIGSFIDIYQQEGTRGLWRGVVPTAQRA 204
Score = 40.8 bits (94), Expect = 0.001
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPR-----YRGILDCVHQSYRAEGWR 245
K + GG + IV+ T+PVD+ K+RLQ G R YRG+ + + + EG
Sbjct: 39 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 98
Query: 246 VFTRGLASTLLRAFPVNAATFATVTV 271
G+A LLR A++ T+ +
Sbjct: 99 ALYSGIAPALLR-----QASYGTIKI 119
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 92.8 bits (229), Expect = 3e-19
Identities = 80/274 (29%), Positives = 125/274 (45%), Gaps = 20/274 (7%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKP-----QYRGTLHCFKSIIKQESVL 56
A DFLAG P + VK+ LQVQ K QY+G + C I K++ VL
Sbjct: 9 AKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVL 68
Query: 57 GLYKGLGSPLMGLTFINALVFGVQGNTLRA-LGHDSPLNQF--------LAGAAAGAIQC 107
++G + ++ AL F + + LG QF +G AAGA
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSL 128
Query: 108 VICCPMELAKTRL--QLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSF 165
P++ A+TRL + +G R ++G DCL +I +G+RG+ +G ++
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYR 188
Query: 166 GVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRG 224
YF YD L +P + +V ++A + + +S YP D V+ R+ G +G
Sbjct: 189 AAYFGVYDTAKGMLP-DPKNTHIVVSWMIAQTVTAVAGVVS-YPFDTVRRRMMMQSGRKG 246
Query: 225 AP-RYRGILDCVHQSYRAEGWRVFTRGLASTLLR 257
A Y G +DC + +R EG + F +G S +LR
Sbjct: 247 ADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLR 280
Score = 67.0 bits (162), Expect = 2e-11
Identities = 53/181 (29%), Positives = 86/181 (47%), Gaps = 10/181 (5%)
Query: 96 FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPA----RTYKGSLDCLAQIYGHEGLRGVN 151
FLAG A AI P+E K LQ+Q A + YKG +DC+ +I +G+
Sbjct: 12 FLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFW 71
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRAL--GCEPGDRL--LVPKLLLAGGTSGIVSWLST 207
RG ++ ++R P+ + F D + G + + L +GG +G S
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFV 131
Query: 208 YPVDVVKSRLQAD-GLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAAT 265
YP+D ++RL AD G G R +RG+ DC+ + +++G R +G + ++ AA
Sbjct: 132 YPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAY 191
Query: 266 F 266
F
Sbjct: 192 F 192
Score = 60.1 bits (144), Expect = 2e-09
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 13/183 (7%)
Query: 7 AGCAGGVAGVLVGHPFDTVKVRLQV---QSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
+G A G + +P D + RL +S + ++RG C I K + + GLY+G
Sbjct: 119 SGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFS 178
Query: 64 SPLMGLTFINALVFGVQGNTLRALGHDSPLN-----QFLAGAAAGAIQCVICCPMELAKT 118
+ G+ A FGV +T + + D P N ++ A+ V+ P + +
Sbjct: 179 VSVQGIIIYRAAYFGVY-DTAKGMLPD-PKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRR 236
Query: 119 RLQLQDA--GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALT 176
R+ +Q G Y G++DC +I+ EG + +G S +LR V L YD L
Sbjct: 237 RMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVL-YDELK 295
Query: 177 RAL 179
+ +
Sbjct: 296 KVI 298
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADG----LRGAPRYRGILDCVHQSYRAEGWRV 246
K LAGG + +S + P++ VK LQ + +Y+GI+DC+ + + +G
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 247 FTRGLASTLLRAFPVNAATFA 267
F RG + ++R FP A FA
Sbjct: 70 FWRGNLANVIRYFPTQALNFA 90
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 91.7 bits (226), Expect = 7e-19
Identities = 79/273 (28%), Positives = 126/273 (46%), Gaps = 21/273 (7%)
Query: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSP 65
+AG G P D +KV +QV + K L +S++ + + L++G G
Sbjct: 190 VAGAVAGAVSRTGTAPLDRLKVFMQVHA-SKTNRLNILGGLRSMVLEGGIRSLWRGNGIN 248
Query: 66 LMGLTFINALVFGVQGNTLRA-LGHDSPLN---QFLAGAAAGAIQCVICCPMELAKTRLQ 121
++ + +A+ F RA LG L+ +F+AG+ AGA I PME+ KTRL
Sbjct: 249 VLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLT 308
Query: 122 LQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRAL-- 179
L+ G YKG LDC +I EG R RG + +L P G+ Y+ L
Sbjct: 309 LRRTGQ---YKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQ 365
Query: 180 -----GCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRGAPRYRGILD 233
+PG +LV LL G S +++YP+ +V++R+QA + G P+ +L
Sbjct: 366 QYSHDSADPG--ILV--LLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQL-SMLG 420
Query: 234 CVHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
+ EG R RG+A ++ P + ++
Sbjct: 421 LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISY 453
Score = 70.9 bits (172), Expect = 1e-12
Identities = 49/184 (26%), Positives = 85/184 (46%), Gaps = 10/184 (5%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGS 64
F+AG G + +P + +K RL ++ QY+G L C + I+++E Y+G
Sbjct: 283 FVAGSLAGATAQTIIYPMEVLKTRLTLRRTG--QYKGLLDCARRILEREGPRAFYRGYLP 340
Query: 65 PLMGL---TFINALVFGVQGNT-LRALGHDSPLNQFLAGAAAGAIQC----VICCPMELA 116
++G+ I+ V+ N L+ HDS L A G I + P+ L
Sbjct: 341 NVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALV 400
Query: 117 KTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALT 176
+TR+Q Q + L L I EG+RG+ RG+ ++ P+ + ++ Y+ +
Sbjct: 401 RTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMK 460
Query: 177 RALG 180
+ALG
Sbjct: 461 QALG 464
Score = 70.5 bits (171), Expect = 2e-12
Identities = 51/178 (28%), Positives = 86/178 (48%), Gaps = 9/178 (5%)
Query: 95 QFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGM 154
Q +AGA AGA+ P++ K +Q+ + R L L + G+R + RG
Sbjct: 188 QLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRL--NILGGLRSMVLEGGIRSLWRGN 245
Query: 155 VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVK 214
+L+ P + F+ Y+ + RA+ + L V + +AG +G + YP++V+K
Sbjct: 246 GINVLKIAPESAIKFMAYEQIKRAI-LGQQETLHVQERFVAGSLAGATAQTIIYPMEVLK 304
Query: 215 SRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFP---VNAATFATV 269
+RL LR +Y+G+LDC + EG R F RG +L P ++ A + T+
Sbjct: 305 TRLT---LRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETL 359
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 90.9 bits (224), Expect = 1e-18
Identities = 78/281 (27%), Positives = 125/281 (44%), Gaps = 31/281 (11%)
Query: 5 FLAGCAGGVAGVLVG---HPFDTVKVRLQVQ------SVEKPQYRGTLHCFKSIIKQESV 55
F AG V+G++ PFD +K+R Q+Q S +Y G L + I+++E
Sbjct: 16 FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGP 75
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQ-------FLAGAAAGAIQCV 108
+KG P L+ V + L L H + F+ G A + +
Sbjct: 76 TAFWKG-HVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
Query: 109 ICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVY 168
P+++ +TR Q G + Y + +Y EG + +G+ TL+ P G+
Sbjct: 135 TVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 169 FLTYDALTR----ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRG 224
F Y +L A+ E G + + LL G +G++S TYP+D+ K RLQ G
Sbjct: 193 FSCYSSLKHLYKWAIPAE-GKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
Query: 225 A-------PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258
A RY+G++DC Q + EG F +GL+ +LL+A
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292
Score = 68.9 bits (167), Expect = 5e-12
Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 10/178 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQD-----AGPARTYKGSLDCLAQIYGHEGLRGVN 151
+AG+ +G + + P ++ K R QLQ + P+ Y G L QI EG
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRALGC-EPGDRLLVPKLLLAGGTSGIVSWLSTYPV 210
+G V + V FL+++ LT + D + GG + ++ L+ +PV
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 211 DVVKSRLQADGLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFA 267
DV+++R A +G P+ Y + V YR+EG +VF +GLA TL+ FP F+
Sbjct: 140 DVLRTRFAA---QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
Score = 68.6 bits (166), Expect = 7e-12
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61
++ F+ G L HP D ++ R Q E Y H ++ + E YKG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQG-EPKVYNTLRHAVGTMYRSEGPQVFYKG 177
Query: 62 LGSPLMGLTFINALVFGVQGNTLRALGHDSP--------LNQFLAGAAAGAIQCVICCPM 113
L L+ + L F + P L L G+ AG I + P+
Sbjct: 178 LAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPL 237
Query: 114 ELAKTRLQLQDA-------GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFG 166
+L K RLQ+ G R YKG +DC Q+ EG G +G+ +LL+ S G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 167 VYFLTYDALTRALGC 181
F +Y+ C
Sbjct: 298 FMFFSYEFFCNVFHC 312
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 90.9 bits (224), Expect = 1e-18
Identities = 78/281 (27%), Positives = 125/281 (44%), Gaps = 31/281 (11%)
Query: 5 FLAGCAGGVAGVLVG---HPFDTVKVRLQVQ------SVEKPQYRGTLHCFKSIIKQESV 55
F AG V+G++ PFD +K+R Q+Q S +Y G L + I+++E
Sbjct: 16 FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGP 75
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQ-------FLAGAAAGAIQCV 108
+KG P L+ V + L L H + F+ G A + +
Sbjct: 76 TAFWKG-HVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
Query: 109 ICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVY 168
P+++ +TR Q G + Y + +Y EG + +G+ TL+ P G+
Sbjct: 135 TVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 169 FLTYDALTR----ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRG 224
F Y +L A+ E G + + LL G +G++S TYP+D+ K RLQ G
Sbjct: 193 FSCYSSLKHLYKWAIPAE-GKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
Query: 225 A-------PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258
A RY+G++DC Q + EG F +GL+ +LL+A
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292
Score = 68.9 bits (167), Expect = 5e-12
Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 10/178 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQD-----AGPARTYKGSLDCLAQIYGHEGLRGVN 151
+AG+ +G + + P ++ K R QLQ + P+ Y G L QI EG
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRALGC-EPGDRLLVPKLLLAGGTSGIVSWLSTYPV 210
+G V + V FL+++ LT + D + GG + ++ L+ +PV
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 211 DVVKSRLQADGLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFA 267
DV+++R A +G P+ Y + V YR+EG +VF +GLA TL+ FP F+
Sbjct: 140 DVLRTRFAA---QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
Score = 68.6 bits (166), Expect = 7e-12
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61
++ F+ G L HP D ++ R Q E Y H ++ + E YKG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQG-EPKVYNTLRHAVGTMYRSEGPQVFYKG 177
Query: 62 LGSPLMGLTFINALVFGVQGNTLRALGHDSP--------LNQFLAGAAAGAIQCVICCPM 113
L L+ + L F + P L L G+ AG I + P+
Sbjct: 178 LAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPL 237
Query: 114 ELAKTRLQLQDA-------GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFG 166
+L K RLQ+ G R YKG +DC Q+ EG G +G+ +LL+ S G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 167 VYFLTYDALTRALGC 181
F +Y+ C
Sbjct: 298 FMFFSYEFFCNVFHC 312
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 90.9 bits (224), Expect = 1e-18
Identities = 78/281 (27%), Positives = 125/281 (44%), Gaps = 31/281 (11%)
Query: 5 FLAGCAGGVAGVLVG---HPFDTVKVRLQVQ------SVEKPQYRGTLHCFKSIIKQESV 55
F AG V+G++ PFD +K+R Q+Q S +Y G L + I+++E
Sbjct: 16 FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGP 75
Query: 56 LGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQ-------FLAGAAAGAIQCV 108
+KG P L+ V + L L H + F+ G A + +
Sbjct: 76 TAFWKG-HVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATL 134
Query: 109 ICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVY 168
P+++ +TR Q G + Y + +Y EG + +G+ TL+ P G+
Sbjct: 135 TVHPVDVLRTRFAAQ--GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQ 192
Query: 169 FLTYDALTR----ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRG 224
F Y +L A+ E G + + LL G +G++S TYP+D+ K RLQ G
Sbjct: 193 FSCYSSLKHLYKWAIPAE-GKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEH 251
Query: 225 A-------PRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258
A RY+G++DC Q + EG F +GL+ +LL+A
Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292
Score = 68.9 bits (167), Expect = 5e-12
Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 10/178 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQD-----AGPARTYKGSLDCLAQIYGHEGLRGVN 151
+AG+ +G + + P ++ K R QLQ + P+ Y G L QI EG
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 152 RGMVSTLLRETPSFGVYFLTYDALTRALGC-EPGDRLLVPKLLLAGGTSGIVSWLSTYPV 210
+G V + V FL+++ LT + D + GG + ++ L+ +PV
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 211 DVVKSRLQADGLRGAPR-YRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFA 267
DV+++R A +G P+ Y + V YR+EG +VF +GLA TL+ FP F+
Sbjct: 140 DVLRTRFAA---QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFS 194
Score = 68.6 bits (166), Expect = 7e-12
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%)
Query: 2 ALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKG 61
++ F+ G L HP D ++ R Q E Y H ++ + E YKG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQG-EPKVYNTLRHAVGTMYRSEGPQVFYKG 177
Query: 62 LGSPLMGLTFINALVFGVQGNTLRALGHDSP--------LNQFLAGAAAGAIQCVICCPM 113
L L+ + L F + P L L G+ AG I + P+
Sbjct: 178 LAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPL 237
Query: 114 ELAKTRLQLQDA-------GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFG 166
+L K RLQ+ G R YKG +DC Q+ EG G +G+ +LL+ S G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 167 VYFLTYDALTRALGC 181
F +Y+ C
Sbjct: 298 FMFFSYEFFCNVFHC 312
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 89.7 bits (221), Expect = 3e-18
Identities = 84/286 (29%), Positives = 125/286 (43%), Gaps = 26/286 (9%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGS 64
FLAG G P D VKV LQ + ++ G +++ ++E LGLYKG G+
Sbjct: 40 FLAGGIAGCCAKTTVAPLDRVKVLLQAHN-HHYKHLGVFSALRAVPQKEGFLGLYKGNGA 98
Query: 65 PLMGLTFINALVFGV--QGNTL--RALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRL 120
++ + A+ F TL LG +++ +AG+ AG + P+++ + RL
Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRL 158
Query: 121 QLQDAGPARTYKGSLDCLAQIYGHEG-LRGVNRGMVSTLLRETPSFGVYFLTYDALTRA- 178
Q G +Y G + IY EG G RG++ T+L P GV F T+ L
Sbjct: 159 AFQVKGE-HSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVG 217
Query: 179 -------LGCEPGDR--LLVPKL---LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAP 226
LG D +LV K LL GG +G ++ +YP DV + R+Q + P
Sbjct: 218 LSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTV--LP 275
Query: 227 RYRGIL---DCVHQSYRAEGWRV-FTRGLASTLLRAFPVNAATFAT 268
+ L D + Y G R RGL+ +R P A F T
Sbjct: 276 EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTT 321
Score = 75.5 bits (184), Expect = 5e-14
Identities = 58/192 (30%), Positives = 88/192 (45%), Gaps = 23/192 (11%)
Query: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSI-IKQESVLGLYKGLGS 64
+AG G+ V+ +P D V+VRL Q + Y G +H FK+I K+ G Y+GL
Sbjct: 135 MAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMP 194
Query: 65 PLMGLTFINALVFGVQGNTLRALG------------HDSP-------LNQFLAGAAAGAI 105
++G+ + F G TL+++G D+P L G AGAI
Sbjct: 195 TILGMAPYAGVSFFTFG-TLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAI 253
Query: 106 QCVICCPMELAKTRLQLQDAGPA-RTYKGSLDCLAQIYGHEGLR-GVNRGMVSTLLRETP 163
I P ++ + R+QL P D + +YGH G+R G+ RG+ +R P
Sbjct: 254 AQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIP 313
Query: 164 SFGVYFLTYDAL 175
S V F TY+ +
Sbjct: 314 SQAVAFTTYELM 325
Score = 62.4 bits (150), Expect = 5e-10
Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 9/179 (5%)
Query: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYK--GSLDCLAQIYGHEGLRGV 150
L FLAG AG P++ K LQ + YK G L + EG G+
Sbjct: 37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHN----HHYKHLGVFSALRAVPQKEGFLGL 92
Query: 151 NRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPV 210
+G + ++R P + F+ ++ + + G V +L+ AG +G+ + + TYP+
Sbjct: 93 YKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLM-AGSMAGMTAVICTYPL 151
Query: 211 DVVKSRLQADGLRGAPRYRGILDCVHQSYRAE-GWRVFTRGLASTLLRAFPVNAATFAT 268
D+V+ RL A ++G Y GI+ Y E G+ F RGL T+L P +F T
Sbjct: 152 DMVRVRL-AFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFT 209
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 89.4 bits (220), Expect = 4e-18
Identities = 76/308 (24%), Positives = 133/308 (43%), Gaps = 44/308 (14%)
Query: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQ-----VQSVEKPQYR----------------- 40
L AG GG G + P + +K RLQ +++V PQ
Sbjct: 13 LHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTP 72
Query: 41 GTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALG-----HDSPLNQ 95
G KSI+++E L++GLG L+G+ A+ F + + ++
Sbjct: 73 GLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHI 132
Query: 96 FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMV 155
F AG+AA I + P+ + KTR+QL+ +L C +Y EG+RG RG+
Sbjct: 133 FSAGSAA-FITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
Query: 156 STLLRETPSFGVYFLTYDALTRAL----------GCEPGDRLLVPKLLLAGGTSGIVSWL 205
++ + + + F Y++L + L G E + A + G S +
Sbjct: 192 ASYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCI 250
Query: 206 STYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAAT 265
+ YP +V+++RL+ +G +Y+ + +R EG+ F RGL + L+R P A
Sbjct: 251 A-YPHEVIRTRLREEG----TKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIV 305
Query: 266 FATVTVVL 273
+T +++
Sbjct: 306 LSTYELIV 313
Score = 59.7 bits (143), Expect = 3e-09
Identities = 48/190 (25%), Positives = 76/190 (40%), Gaps = 30/190 (15%)
Query: 90 DSPLNQFLAGAAAGAIQCVICCPMELAKTRLQ------------------LQDAG---PA 128
++ L AG G + + CP+E+ KTRLQ + AG P
Sbjct: 9 ENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPT 68
Query: 129 RTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLL 188
G L I EG + + RG+ L+ PS VYF Y E + +
Sbjct: 69 SVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAK-----EQFNGIF 123
Query: 189 VPKL----LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGW 244
VP + + G++ ++ P+ +VK+R+Q + + L C Y+ EG
Sbjct: 124 VPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGI 183
Query: 245 RVFTRGLAST 254
R F RGL ++
Sbjct: 184 RGFYRGLTAS 193
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 19/189 (10%)
Query: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQV-QSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
F AG A + L+ +P VK R+Q+ Q V + TL C + + + E + G Y+GL
Sbjct: 133 FSAGSAAFITNSLM-NPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLT 191
Query: 64 SPLMGL--TFINALVFGVQGNTLR-------ALGHDSPLNQFLAGAAAGAIQ--CVICC- 111
+ G+ T I ++ L+ A G + F AA A+ C C
Sbjct: 192 ASYAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
Query: 112 -PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFL 170
P E+ +TRL+ + YK + ++ EG RG+ + L+R+ P+ +
Sbjct: 252 YPHEVIRTRLREEGT----KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
Query: 171 TYDALTRAL 179
TY+ + L
Sbjct: 308 TYELIVYLL 316
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 89.0 bits (219), Expect = 5e-18
Identities = 78/276 (28%), Positives = 111/276 (40%), Gaps = 36/276 (13%)
Query: 8 GCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLM 67
G G+ GV P D K RLQ Q + Y C ++ E G+Y+G L
Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLT 74
Query: 68 GLTFINALVFGVQGNTLRALGHDSP----LNQFLAGAAAGAIQCVICCPMELAKTRLQLQ 123
+T A+ L D L + LAG AG Q ++ PME+ K +QLQ
Sbjct: 75 LVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLK--IQLQ 132
Query: 124 DAG---------------------------PARTYKGSLDCLAQIYGHEGLRGVNRGMVS 156
DAG PA + + G+ G+ +G+ +
Sbjct: 133 DAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGA 192
Query: 157 TLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSR 216
TLLR+ P VYF + L + ++ LAG +G + ++ P DVVK+R
Sbjct: 193 TLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTR 252
Query: 217 LQADGLRGA--PRYRGILDCVHQSYRAEGWRVFTRG 250
LQ+ RG Y GILDC + R EG F +G
Sbjct: 253 LQS-LQRGVNEDTYSGILDCARKILRHEGPSAFLKG 287
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/205 (29%), Positives = 87/205 (42%), Gaps = 40/205 (19%)
Query: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQ---------------------------VQSVEK 36
+ LAGC G V+V P + +K++LQ V++
Sbjct: 106 EMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAA 165
Query: 37 PQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQ- 95
P+ T + +++ + GLYKGLG+ L+ + + F + N L LG + +
Sbjct: 166 PRPTAT-QLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFAN-LNQLGRPASEEKS 223
Query: 96 -----FLAGAAAGAIQCVICCPMELAKTRLQ-LQDAGPARTYKGSLDCLAQIYGHEGLRG 149
FLAG AG+ V P ++ KTRLQ LQ TY G LDC +I HEG
Sbjct: 224 PFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSA 283
Query: 150 VNRGMVSTLLRETPSFG----VYFL 170
+G L P FG VYFL
Sbjct: 284 FLKGAYCRALVIAPLFGIAQVVYFL 308
Score = 60.8 bits (146), Expect = 1e-09
Identities = 44/133 (33%), Positives = 62/133 (46%), Gaps = 2/133 (1%)
Query: 95 QFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGM 154
+ + G AG I P++LAKTRLQ Q G R Y DCL + EG G+ RG
Sbjct: 11 KLINGGIAGLIGVTCVFPIDLAKTRLQNQQNG-QRVYTSMSDCLIKTVRSEGYFGMYRGA 69
Query: 155 VSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVK 214
L TP + D L + G +L + K +LAG +G + T P++++K
Sbjct: 70 AVNLTLVTPEKAIKLAANDFFRHQLS-KDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLK 128
Query: 215 SRLQADGLRGAPR 227
+LQ G A R
Sbjct: 129 IQLQDAGRIAAQR 141
Score = 45.1 bits (105), Expect = 8e-05
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 186 RLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWR 245
++ +P L+ GG +G++ +P+D+ K+RLQ + G Y + DC+ ++ R+EG+
Sbjct: 5 QISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEGYF 63
Query: 246 VFTRGLASTLLRAFPVNAATFA 267
RG A L P A A
Sbjct: 64 GMYRGAAVNLTLVTPEKAIKLA 85
Score = 43.9 bits (102), Expect = 2e-04
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQ--VQSVEKPQYRGTLHCFKSIIKQESVLGLYK 60
+ FLAGC G A + +P D VK RLQ + V + Y G L C + I++ E K
Sbjct: 227 VSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLK 286
Query: 61 G 61
G
Sbjct: 287 G 287
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 88.6 bits (218), Expect = 6e-18
Identities = 77/272 (28%), Positives = 121/272 (44%), Gaps = 24/272 (8%)
Query: 10 AGGVAGVL---VGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
AGG AG + P D +KV +QV + + G + F +I++ L++G G +
Sbjct: 192 AGGGAGAVSRTCTAPLDRLKVLMQVHA-SRSNNMGIVGGFTQMIREGGARSLWRGNGINV 250
Query: 67 MGLTFINALVFGVQGNTLRALGHDSPL----NQFLAGAAAGAIQCVICCPMELAKTRLQL 122
+ + +A+ F R +G D + +AG+ AGAI PME+ KTR+ L
Sbjct: 251 LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL 310
Query: 123 QDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRAL--- 179
+ G Y G LDC +I EG+ +G V +L P G+ Y+ L A
Sbjct: 311 RKTGQ---YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
Query: 180 ----GCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRGAPRYRGILDC 234
+PG V LL G S L++YP+ +V++R+QA + GAP +
Sbjct: 368 YAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSL 422
Query: 235 VHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
R EG RGLA ++ P + ++
Sbjct: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/176 (26%), Positives = 84/176 (47%), Gaps = 9/176 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVS 156
+AG AGA+ P++ K +Q+ G + Q+ G R + RG
Sbjct: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVH--ASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
Query: 157 TLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSR 216
+L+ P + F+ Y+ + R +G + + L + + L+AG +G ++ S YP++V+K+R
Sbjct: 249 NVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 217 LQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFP---VNAATFATV 269
+ LR +Y G+LDC + EG F +G +L P ++ A + T+
Sbjct: 308 M---ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
Score = 35.8 bits (81), Expect = 0.048
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 8 GCAGGVAGVLVGHPFDTVKVRLQVQ-SVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
G G L +P V+ R+Q Q S+E FK I++ E GLY+GL
Sbjct: 384 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 443
Query: 67 MGLTFINALVFGVQGNTLRALGHDS 91
M + ++ + V N LG S
Sbjct: 444 MKVIPAVSISYVVYENLKITLGVQS 468
Score = 33.1 bits (74), Expect = 0.31
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 193 LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLA 252
L+AGG +G VS T P+D +K +Q R GI+ Q R G R RG
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--NNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 253 STLLRAFPVNAATF 266
+L+ P +A F
Sbjct: 248 INVLKIAPESAIKF 261
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 88.6 bits (218), Expect = 6e-18
Identities = 77/272 (28%), Positives = 121/272 (44%), Gaps = 24/272 (8%)
Query: 10 AGGVAGVL---VGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
AGG AG + P D +KV +QV + + G + F +I++ L++G G +
Sbjct: 226 AGGGAGAVSRTCTAPLDRLKVLMQVHA-SRSNNMGIVGGFTQMIREGGARSLWRGNGINV 284
Query: 67 MGLTFINALVFGVQGNTLRALGHDSPL----NQFLAGAAAGAIQCVICCPMELAKTRLQL 122
+ + +A+ F R +G D + +AG+ AGAI PME+ KTR+ L
Sbjct: 285 LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL 344
Query: 123 QDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRAL--- 179
+ G Y G LDC +I EG+ +G V +L P G+ Y+ L A
Sbjct: 345 RKTGQ---YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 401
Query: 180 ----GCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRGAPRYRGILDC 234
+PG V LL G S L++YP+ +V++R+QA + GAP +
Sbjct: 402 YAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSL 456
Query: 235 VHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
R EG RGLA ++ P + ++
Sbjct: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 488
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/176 (26%), Positives = 84/176 (47%), Gaps = 9/176 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVS 156
+AG AGA+ P++ K +Q+ G + Q+ G R + RG
Sbjct: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVH--ASRSNNMGIVGGFTQMIREGGARSLWRGNGI 282
Query: 157 TLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSR 216
+L+ P + F+ Y+ + R +G + + L + + L+AG +G ++ S YP++V+K+R
Sbjct: 283 NVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 217 LQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFP---VNAATFATV 269
+ LR +Y G+LDC + EG F +G +L P ++ A + T+
Sbjct: 342 M---ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 394
Score = 35.8 bits (81), Expect = 0.048
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 8 GCAGGVAGVLVGHPFDTVKVRLQVQ-SVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
G G L +P V+ R+Q Q S+E FK I++ E GLY+GL
Sbjct: 418 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 477
Query: 67 MGLTFINALVFGVQGNTLRALGHDS 91
M + ++ + V N LG S
Sbjct: 478 MKVIPAVSISYVVYENLKITLGVQS 502
Score = 33.1 bits (74), Expect = 0.31
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 193 LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLA 252
L+AGG +G VS T P+D +K +Q R GI+ Q R G R RG
Sbjct: 224 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--NNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 253 STLLRAFPVNAATF 266
+L+ P +A F
Sbjct: 282 INVLKIAPESAIKF 295
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 88.6 bits (218), Expect = 6e-18
Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 22/188 (11%)
Query: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSP 65
+AG G+ +V +P D +K RL +Q++ +P YRG LH F +I +QE L LY+G
Sbjct: 111 MAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG---- 166
Query: 66 LMGLTFINALVFGVQGNTLRALGHDSPLN----------QFLAGAAAGAIQCVICCPMEL 115
+ LT + AL F G+ L + + N F A A+ + P E
Sbjct: 167 -VSLTVVGALPFSA-GSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFET 224
Query: 116 AKTRLQLQ------DAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYF 169
K ++Q Q G + G++DC QI +G+ G+ G+ + LL+ P FG+ F
Sbjct: 225 VKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMF 284
Query: 170 LTYDALTR 177
T++ R
Sbjct: 285 STFEFCKR 292
Score = 71.2 bits (173), Expect = 1e-12
Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 15/272 (5%)
Query: 9 CAG--GVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
CAG G + + P + V QV V + RG + + E + L+KG
Sbjct: 18 CAGLAGTLSLSLTAPLELATVLAQV-GVVRGHARGPWATGHRVWRAEGLRALWKGNAVAC 76
Query: 67 MGLTFINALVFGVQGNTLRA----LGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQL 122
+ L +A+ + LGH S + +AG+ AG + ++ P +L KTRL +
Sbjct: 77 LRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIM 136
Query: 123 QDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCE 182
Q+ +Y+G L + IY EG + RG+ T++ P L Y L + +
Sbjct: 137 QNI-LEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEK-IWNG 194
Query: 183 PGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADG-----LRGAP-RYRGILDCVH 236
P D+ +P+ + V+ ++P + VK ++QA G + G +DC
Sbjct: 195 PRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFR 254
Query: 237 QSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
Q +A+G GL + LL+ P F+T
Sbjct: 255 QIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
Score = 44.3 bits (103), Expect = 1e-04
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKP-------QYRGTLHCFKSIIKQESVL 56
+F C + PF+TVK ++Q QS P + G + CF+ I+K + VL
Sbjct: 204 NFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVL 263
Query: 57 GLYKGLGSPLMGLTFINALVF 77
GL+ GL + L+ + ++F
Sbjct: 264 GLWNGLTANLLKIVPYFGIMF 284
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 88.6 bits (218), Expect = 6e-18
Identities = 77/272 (28%), Positives = 121/272 (44%), Gaps = 24/272 (8%)
Query: 10 AGGVAGVL---VGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
AGG AG + P D +KV +QV + + G + F +I++ L++G G +
Sbjct: 212 AGGGAGAVSRTCTAPLDRLKVLMQVHA-SRSNNMGIVGGFTQMIREGGARSLWRGNGINV 270
Query: 67 MGLTFINALVFGVQGNTLRALGHDSPL----NQFLAGAAAGAIQCVICCPMELAKTRLQL 122
+ + +A+ F R +G D + +AG+ AGAI PME+ KTR+ L
Sbjct: 271 LKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMAL 330
Query: 123 QDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRAL--- 179
+ G Y G LDC +I EG+ +G V +L P G+ Y+ L A
Sbjct: 331 RKTGQ---YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 387
Query: 180 ----GCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD-GLRGAPRYRGILDC 234
+PG V LL G S L++YP+ +V++R+QA + GAP +
Sbjct: 388 YAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSL 442
Query: 235 VHQSYRAEGWRVFTRGLASTLLRAFPVNAATF 266
R EG RGLA ++ P + ++
Sbjct: 443 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 474
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/176 (26%), Positives = 84/176 (47%), Gaps = 9/176 (5%)
Query: 97 LAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVS 156
+AG AGA+ P++ K +Q+ G + Q+ G R + RG
Sbjct: 211 VAGGGAGAVSRTCTAPLDRLKVLMQVH--ASRSNNMGIVGGFTQMIREGGARSLWRGNGI 268
Query: 157 TLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSR 216
+L+ P + F+ Y+ + R +G + + L + + L+AG +G ++ S YP++V+K+R
Sbjct: 269 NVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 327
Query: 217 LQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFP---VNAATFATV 269
+ LR +Y G+LDC + EG F +G +L P ++ A + T+
Sbjct: 328 M---ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 380
Score = 35.8 bits (81), Expect = 0.048
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 8 GCAGGVAGVLVGHPFDTVKVRLQVQ-SVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
G G L +P V+ R+Q Q S+E FK I++ E GLY+GL
Sbjct: 404 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 463
Query: 67 MGLTFINALVFGVQGNTLRALGHDS 91
M + ++ + V N LG S
Sbjct: 464 MKVIPAVSISYVVYENLKITLGVQS 488
Score = 33.1 bits (74), Expect = 0.31
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 193 LLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLA 252
L+AGG +G VS T P+D +K +Q R GI+ Q R G R RG
Sbjct: 210 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--NNMGIVGGFTQMIREGGARSLWRGNG 267
Query: 253 STLLRAFPVNAATF 266
+L+ P +A F
Sbjct: 268 INVLKIAPESAIKF 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,579,756
Number of Sequences: 37866
Number of extensions: 492607
Number of successful extensions: 2313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1594
Number of HSP's gapped (non-prelim): 243
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.