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Search of human proteins with 8393956
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
(391 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 782 0.0
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 457 e-129
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 454 e-128
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 341 6e-94
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 338 6e-93
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 327 1e-89
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 320 1e-87
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 317 1e-86
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 303 2e-82
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 284 8e-77
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 284 8e-77
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 284 8e-77
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 284 8e-77
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 272 3e-73
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 272 3e-73
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 245 4e-65
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 229 3e-60
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 207 1e-53
gi|170295807 neuroserpin precursor [Homo sapiens] 188 6e-48
gi|4826904 neuroserpin precursor [Homo sapiens] 188 6e-48
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 187 1e-47
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 178 7e-45
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 171 8e-43
>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
Length = 391
Score = 782 bits (2019), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60
MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE
Sbjct: 1 MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60
Query: 61 KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120
KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY
Sbjct: 61 KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120
Query: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM
Sbjct: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
Query: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN
Sbjct: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL
Sbjct: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
Query: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG 360
AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG
Sbjct: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG 360
Query: 361 HENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
HENVHCNHPFLFFIRHNESNSILFFGRFSSP
Sbjct: 361 HENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 457 bits (1176), Expect = e-129
Identities = 228/392 (58%), Positives = 296/392 (75%), Gaps = 3/392 (0%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60
M+SL +T+ FDLF++ +K+ + NIF+SP+ I +A+GMVLLG + TA Q+++V H +
Sbjct: 1 MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFD 60
Query: 61 KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120
+ T+++ KA V + + VH QFQK LTE +K T+ YEL I N+LFGEKTYLFLQ+Y
Sbjct: 61 QVTENTTGKAATYHV-DRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119
Query: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
LD ++K+Y S+E VDF NA +ESRKKINSWVES+TNEKIK+L P+G+I S+T LVLVN
Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179
Query: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
+YFKGQW+++F KE+TKEEKFW NK+T KS+QMM Q SF F LED+QAK+L IPYK
Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGK 239
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
DLSM VLLPN+IDGL+K+ +K++ EKL+EWTS +M E +V+LHLPRF+VE+ YDL+ L
Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTL 299
Query: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATG-IGFTVTSAP 359
MGM D F+ AD SGM+ GL LH +FV VTEEG EAAAAT +GF +
Sbjct: 300 RTMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+E HCNHPFLFFIR N++NSILF+GRFSSP
Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 454 bits (1168), Expect = e-128
Identities = 228/392 (58%), Positives = 294/392 (75%), Gaps = 3/392 (0%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60
M+SL +T+ FDLF++ +K+ + NIF+SP+ I +A+GMVLLG + TA Q+ +V H +
Sbjct: 1 MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFD 60
Query: 61 KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120
+ T+++ KA V + + VH QFQK LTE +K T+ YEL I N+LFGEKTY FLQ+Y
Sbjct: 61 QVTENTTEKAATYHV-DRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119
Query: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
LD ++K+Y S+E DF NA +ESRKKINSWVES+TNEKIK+LFPDG+I + T LVLVN
Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179
Query: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
+YFKGQW+ +FKKENTKEEKFW NK+T KSVQMM Q +SF+F LED+QAK+L IPYK
Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGK 239
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
DLSM VLLPN+IDGL+K+ +K++ EKL+EWTS +M E V+LHLPRF++E+ YDL+ L
Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTL 299
Query: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG 360
MGM + F+ AD SGM+ GL K LH +FV VTEEG EAAAAT + S+P
Sbjct: 300 RTMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPS 358
Query: 361 -HENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+E CNHPFLFFIR N++NSILF+GRFSSP
Sbjct: 359 TNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 341 bits (875), Expect = 6e-94
Identities = 176/397 (44%), Positives = 259/397 (65%), Gaps = 6/397 (1%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEV--F 57
MDSL + +L K+L ++ G NIFFS I T++ +V LG +G TA+Q+ +V F
Sbjct: 1 MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60
Query: 58 HSEKETKSSRIKAEEKEV---IENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTY 114
+ ++ K +++++ + N+E +H FQ ++EI K +DY L N ++GEKTY
Sbjct: 61 NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120
Query: 115 LFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTK 174
F KYL+ ++ Y+ A +PV+FV A+D+ RK INSWVE +T KI++L PD S+ S+T+
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180
Query: 175 LVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILG 234
++LVN +YFKG W+ +F +NT E+ F +N++TSK VQMM +E +A L
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240
Query: 235 IPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGY 294
+ YK+ DLS+ +LLP DI+GLE++ I+ EKL EWTS ME +V LHLP+F++ED Y
Sbjct: 241 LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY 300
Query: 295 DLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFT 354
DL++ L++MGM DAFS+ KAD+SGMSS L+ H +FV + E+GTEAAA +G
Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360
Query: 355 VTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+ + NHPFLFFIRHN++N+ILF+GR SP
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 338 bits (866), Expect = 6e-93
Identities = 180/396 (45%), Positives = 245/396 (61%), Gaps = 22/396 (5%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTND-GNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
M+ L + +TR DLF L + N GNIF SP I +A+ MV LGTRG TA+QL + FH
Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFH- 59
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
E VH +FQ +I+K Y L + NRL+GEKTY FL +
Sbjct: 60 ----------------FNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPE 103
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
+L +K Y A L VDF +A++++RK IN WV+ +T KI +L G + + TKLVLVN
Sbjct: 104 FLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVN 163
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
+YFKG W +F KE T F +NK K+V+MM Q F++ ++EDL+ ++L +PY+
Sbjct: 164 AIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQG 223
Query: 240 NDLSMFVLLPNDID----GLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYD 295
+LSM +LLP+DI+ GL+KI ++++ EKL EWT P +++ +VN+ LPRF++E+ Y
Sbjct: 224 EELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYT 283
Query: 296 LEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTV 355
L + LA +G+ D F+ KAD SGMS ++ K +H SFV V EEGTEAAAAT T
Sbjct: 284 LNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF 343
Query: 356 TSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
EN +HPFLFFIRHN S SILF GRFSSP
Sbjct: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 327 bits (837), Expect = 1e-89
Identities = 169/392 (43%), Positives = 245/392 (62%), Gaps = 1/392 (0%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
M SL + D+FKEL N G NIFFS + +L A+ MVLLG RG T QLE+V H
Sbjct: 1 MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
S + ++ +H +F ++I++ ++ L+I NRL+G KT F Q+
Sbjct: 61 SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
YL EK+Y A L+ VDF + +E+RK IN+WVE+KTN K+ +LF +I S+ +VLVN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
+YFKGQW +F+ T + F +++ + +V+MM Q +F F+++ Q ++L +PY N
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
N LSM +LLP I L++I +++ EWTS +M ER+V +HLPRF++E Y+L ++
Sbjct: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L ++G+ D F++ KAD SGMS GLY K +H S++ V+EEGTEAAAATG V S P
Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
NHPFLFFIRH +N+ILF G+ +SP
Sbjct: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 320 bits (821), Expect = 1e-87
Identities = 176/405 (43%), Positives = 259/405 (63%), Gaps = 14/405 (3%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFH- 58
MDSL +T+ FDLF+E+ K + NIFFSP+ + A+GMV LG R +A Q++EV H
Sbjct: 1 MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60
Query: 59 ---SEKETKSSR--IKAEEKEVIE-NTEA--VHQQFQKFLTEISKLTNDYELNITNRLFG 110
S+ E+K +K+ +++ N E+ V F + L+++ ++ DY L+I NRL+G
Sbjct: 61 NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120
Query: 111 EKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSIS 170
E+ + Q+YLD V ++YH ++E VDF ++SR++IN WVE ++ KIK+LF +I+
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180
Query: 171 SSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQA 230
+ T LVLVN VYFK +W+ F ENT + F +N + +KSV+MMTQ + F+E+++A
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240
Query: 231 KILGIPYKNNDLSMFVLLP----NDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLP 286
+IL + Y LSMFVLLP +++ GLE++ KI+ EK+V W+S +M E V L P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300
Query: 287 RFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAA 346
RF +ED YDL ++L MG+ D F E +AD +G+S LY K +H +FV V E GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360
Query: 347 AATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
AATG + S + NHPFLFFIRHN++ +ILF+GR SP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 317 bits (812), Expect = 1e-86
Identities = 167/391 (42%), Positives = 238/391 (60%), Gaps = 15/391 (3%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60
MD L + +L K L K N N+FFSP+ + A+ MV +G +G TA+Q+ ++
Sbjct: 1 MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60
Query: 61 KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120
K I HQ FQ LTE++K Y L + NRLFGEK+ FL +
Sbjct: 61 KSGGGGDI--------------HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSF 106
Query: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
D +K+Y A +E +DF++A ++SRK IN+WV KT KI +L GS+ T+LVLVN
Sbjct: 107 RDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNA 166
Query: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
VYF+G WD +F KENT+E F ++K+ K VQMM + +F T++ ++ +IL +PY
Sbjct: 167 VYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGK 226
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
+L+M ++LP++ L + +++ EK VEWT M+E +V + LPRF++E+ YD+E+VL
Sbjct: 227 ELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVL 286
Query: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG 360
+GM DAF KAD+SGMS + L K +H SFV V EEGTEAAAAT + A
Sbjct: 287 RNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARF 345
Query: 361 HENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+HPFLFFI+H+++N ILF GRFSSP
Sbjct: 346 VPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 303 bits (775), Expect = 2e-82
Identities = 166/393 (42%), Positives = 233/393 (59%), Gaps = 19/393 (4%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
M++L S L K L + N N+F SPV I +A+ MVLLG +G TA+Q+ +
Sbjct: 1 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
E E +H+ FQ LTE++K Y L NRLFGEKT FL
Sbjct: 61 NTE-----------------EDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLST 103
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
+ + ++YHA L+ + F+ AA+ESRK IN+WV KT KI++L P SI + T+LVLVN
Sbjct: 104 FKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVN 163
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
+YFKG+W+ F + T+E F +N+ + VQMM Q +F + +++A++L +PY
Sbjct: 164 AIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYAR 223
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
+LS+ VLLP+D L + ++ EKL WT P M+ +V + LP+F++++ YD+E+V
Sbjct: 224 KELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESV 283
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L +G+ DAF + KAD S MS+ L KF+H SFV V EEGTEAAAA+
Sbjct: 284 LRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCM 343
Query: 360 GHENVHC-NHPFLFFIRHNESNSILFFGRFSSP 391
C +HPFLFFIRHN +NSILF GRFSSP
Sbjct: 344 ESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 284 bits (727), Expect = 8e-77
Identities = 154/392 (39%), Positives = 224/392 (57%), Gaps = 19/392 (4%)
Query: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
MD L + LFK L ++ N N+FFSP+ I +A+ MV +G +G+TA+Q+ +
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
K+ +H+ FQ L+E+++ Y L NRLFGEKT FL
Sbjct: 61 YKDGD-----------------IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
+ +Y +K+Y A LE + F +E RK IN WV KT KI ++ G++ TKLVLVN
Sbjct: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
+YFKG+W+ +F ++ T+ F N+ K+VQMM + F + +++ ++L +PY
Sbjct: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLELPYVE 222
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
+LSM +LLP+D L + ++ EK WT+ + + KV + LPR ++E+ YDLE
Sbjct: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L +GM DAF E KAD+SGMS+ + K H FV V EEGTEAAAAT + +
Sbjct: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+HPFLFFIRH+++N ILF GRFSSP
Sbjct: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 284 bits (727), Expect = 8e-77
Identities = 154/392 (39%), Positives = 224/392 (57%), Gaps = 19/392 (4%)
Query: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
MD L + LFK L ++ N N+FFSP+ I +A+ MV +G +G+TA+Q+ +
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
K+ +H+ FQ L+E+++ Y L NRLFGEKT FL
Sbjct: 61 YKDGD-----------------IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
+ +Y +K+Y A LE + F +E RK IN WV KT KI ++ G++ TKLVLVN
Sbjct: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
+YFKG+W+ +F ++ T+ F N+ K+VQMM + F + +++ ++L +PY
Sbjct: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLELPYVE 222
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
+LSM +LLP+D L + ++ EK WT+ + + KV + LPR ++E+ YDLE
Sbjct: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L +GM DAF E KAD+SGMS+ + K H FV V EEGTEAAAAT + +
Sbjct: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+HPFLFFIRH+++N ILF GRFSSP
Sbjct: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 284 bits (727), Expect = 8e-77
Identities = 161/416 (38%), Positives = 246/416 (59%), Gaps = 26/416 (6%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFH- 58
M+ L +T +LFK L K + N+F SP I + + MV +G+RG+T Q+ +V
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 59 ------------SEKETKSSRIKAEEK----EVIENTEA---VHQQFQKFLTEISKLTND 99
E T ++ +K + I +A +H F+ + I+ T +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 100 YELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEK 159
Y L N+LFGEK+ F ++Y+ +KYY + + VDF+ A+E+RKKINSWV+++T K
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 160 IKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHS 219
I +L P+GS+ T++VLVN VYFKG+W F+K+ F +N + VQMM
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 220 FSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDI----DGLEKIIDKISPEKLVEWTSPGH 275
+ ++EDL+A+IL +PY D+SMF+LLP++I GLE + +I+ +KL +WTS
Sbjct: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 276 MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSF 335
M E +V +++P+F++E+ Y+L ++L +MGM DAF++ +A++SGMS + L+ + H +
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 336 VAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
V V EEGTEAAA TG T + G +HPFLF I H +N ILFFGRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 284 bits (727), Expect = 8e-77
Identities = 161/416 (38%), Positives = 246/416 (59%), Gaps = 26/416 (6%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFH- 58
M+ L +T +LFK L K + N+F SP I + + MV +G+RG+T Q+ +V
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 59 ------------SEKETKSSRIKAEEK----EVIENTEA---VHQQFQKFLTEISKLTND 99
E T ++ +K + I +A +H F+ + I+ T +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 100 YELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEK 159
Y L N+LFGEK+ F ++Y+ +KYY + + VDF+ A+E+RKKINSWV+++T K
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 160 IKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHS 219
I +L P+GS+ T++VLVN VYFKG+W F+K+ F +N + VQMM
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 220 FSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDI----DGLEKIIDKISPEKLVEWTSPGH 275
+ ++EDL+A+IL +PY D+SMF+LLP++I GLE + +I+ +KL +WTS
Sbjct: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 276 MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSF 335
M E +V +++P+F++E+ Y+L ++L +MGM DAF++ +A++SGMS + L+ + H +
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 336 VAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
V V EEGTEAAA TG T + G +HPFLF I H +N ILFFGRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 272 bits (696), Expect = 3e-73
Identities = 150/392 (38%), Positives = 229/392 (58%), Gaps = 13/392 (3%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
M SL A + F+LF+E+ +GN+FFS + + A+ +V LG + + SQ++++ H
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
T S + + + Q ++ ++I+ DY+L+I N LF EK Y F +
Sbjct: 61 N--TASGYGNSSNSQ-----SGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKD 113
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
Y++ EK Y A +E VDF N +++R+ IN WVE++T+ KIK++ +G ISSS +VLVN
Sbjct: 114 YIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVN 173
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
VYFKG+W F K T F K + K+V MM Q F+ + +ED KIL + Y N
Sbjct: 174 AVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-N 232
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
++M+VLLP + L +I +K++ + L+EWT+P M + V + P+F++E Y+++
Sbjct: 233 GGINMYVLLPE--NDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQY 290
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L A+G+ D F E KAD SG++SG LY + +H S++ VTEEGTEA AATG P
Sbjct: 291 LRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLP 350
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+HPFLF IR + + ILF G+ S P
Sbjct: 351 QSTLFRADHPFLFVIR--KDDIILFSGKVSCP 380
>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 272 bits (696), Expect = 3e-73
Identities = 150/392 (38%), Positives = 229/392 (58%), Gaps = 13/392 (3%)
Query: 1 MDSLGAVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
M SL A + F+LF+E+ +GN+FFS + + A+ +V LG + + SQ++++ H
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
T S + + + Q ++ ++I+ DY+L+I N LF EK Y F +
Sbjct: 61 N--TASGYGNSSNSQ-----SGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKD 113
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
Y++ EK Y A +E VDF N +++R+ IN WVE++T+ KIK++ +G ISSS +VLVN
Sbjct: 114 YIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVN 173
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
VYFKG+W F K T F K + K+V MM Q F+ + +ED KIL + Y N
Sbjct: 174 AVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-N 232
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
++M+VLLP + L +I +K++ + L+EWT+P M + V + P+F++E Y+++
Sbjct: 233 GGINMYVLLPE--NDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQY 290
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L A+G+ D F E KAD SG++SG LY + +H S++ VTEEGTEA AATG P
Sbjct: 291 LRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLP 350
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+HPFLF IR + + ILF G+ S P
Sbjct: 351 QSTLFRADHPFLFVIR--KDDIILFSGKVSCP 380
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 245 bits (626), Expect = 4e-65
Identities = 128/396 (32%), Positives = 227/396 (57%), Gaps = 26/396 (6%)
Query: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
MD+L ++ DLFK+L +K GN+ FSP+ + T++ + +G +G TA+++ +V H
Sbjct: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLH- 59
Query: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
EN + V FQ ++++KL++ Y L + RL+ +K+ +
Sbjct: 60 ----------------FENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTE 103
Query: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
++ ++ Y LE VDF + +E++ +IN+ ++ T+ +++ D S++ TK+++VN
Sbjct: 104 FISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVN 163
Query: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
YF G+W ++F + TKE F +NK+ +K VQMM +F ++ + KI+ +P++N
Sbjct: 164 AAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQN 223
Query: 240 NDLSMFVLLPNDID----GLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYD 295
LSMF+LLP D++ GLEKI +++ E L +WT+P M KV L +P+F+VE D
Sbjct: 224 KHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMID 283
Query: 296 LEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTV 355
+A L +G+ FSE +D+SGMS G+ +H + +TE+G ++ G
Sbjct: 284 PKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPG----A 339
Query: 356 TSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+ ++ +HPF++ IRHN++ +I+FFG+F SP
Sbjct: 340 RILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 229 bits (584), Expect = 3e-60
Identities = 138/394 (35%), Positives = 207/394 (52%), Gaps = 21/394 (5%)
Query: 4 LGAVSTRLGFDLFKEL--KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEK 61
L ++R ++ L K ++ NIF SP+ I TA M LG T QL EVF +
Sbjct: 83 LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT 142
Query: 62 ETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTN-DYELNITNRLFGEKTYLFLQKY 120
++ + ++ +H F K + + N +L NRLFG+K+ F + Y
Sbjct: 143 ISEKT------------SDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETY 190
Query: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180
D E Y A L+P+DF A++SR IN WV +KT +I D+ P +I+ T LVLVN
Sbjct: 191 QDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNT 250
Query: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240
+YFKG W +F ENT++E F+ S S MM Q F + + + ++L +P+K +
Sbjct: 251 IYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGD 309
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300
D++M ++LP L K+ +++PE L EW +EE + +H+PRF +EDG+ L+ L
Sbjct: 310 DITMVLILPKPEKSLAKVEKELTPEVLQEWLD--ELEEMMLVVHMPRFRIEDGFSLKEQL 367
Query: 301 AAMGMGDAFSEHKADYSGM--SSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSA 358
MG+ D FS K+ G+ LY H +F+ V EEG+EAAA+T + S
Sbjct: 368 QDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSL 427
Query: 359 -PGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
P N PFL FIR N+I+F GR ++P
Sbjct: 428 NPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 207 bits (528), Expect = 1e-53
Identities = 118/386 (30%), Positives = 214/386 (55%), Gaps = 21/386 (5%)
Query: 8 STRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSR 67
+T DL++E+ ++ NI FSP+GI + MV LG +G Q+ + ++ET +
Sbjct: 26 NTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTL-KQQETSAG- 83
Query: 68 IKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKY 127
EE V+++ F + IS+ ++ N+ N L+ ++ + ++YL +++
Sbjct: 84 ---EEFFVLKS----------FFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEF 130
Query: 128 YHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQW 187
+ ++++ VDF +A + I++WVE KT+ KIKD+F T+LVLVN +YFKG W
Sbjct: 131 FQSAIKLVDFQDAK-ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDW 189
Query: 188 DREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLED--LQAKILGIPYKNNDLSMF 245
++F+KE+T+ F ++ + MM + + + L ++L + YK ++ S+
Sbjct: 190 KQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLI 249
Query: 246 VLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGM 305
++LP + +E++ I+ +++++W S M+E +V + LPRF+VE D + VL ++ +
Sbjct: 250 IILPAEGMDIEEVEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNI 307
Query: 306 GDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH 365
+ FS D SG++ S +Y + F + E+G+EAA +TGI V +
Sbjct: 308 TEIFSGG-CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFI 366
Query: 366 CNHPFLFFIRHNESNSILFFGRFSSP 391
NHPFLF ++HN + SILF GR ++P
Sbjct: 367 ANHPFLFIMKHNPTESILFMGRVTNP 392
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 188 bits (478), Expect = 6e-48
Identities = 123/392 (31%), Positives = 203/392 (51%), Gaps = 34/392 (8%)
Query: 11 LGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69
L +++ L+ T D NI FSP+ I A+GM+ LG +G+T +E+ HS
Sbjct: 29 LSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQ---KEIRHSMGY------- 78
Query: 70 AEEKEVIENTEAVHQQFQKFLTEISKLT----NDYELNITNRLFGEKTYLFLQKYLDYVE 125
+ ++N E FL E S + + Y + I N LF + + +++L ++
Sbjct: 79 ----DSLKNGEEF-----SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
Query: 126 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKG 185
KY++A++ VDF + IN WVE+ TN +KDL ++T L L+N VYFKG
Sbjct: 130 KYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188
Query: 186 QWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQ------AKILGIPYKN 239
W +F+ ENT+ F + + + MM Q F + D ++L IPY+
Sbjct: 189 NWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEG 248
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
+++SM ++L L + + + + EW + ++++KV ++LPRF VE DL+ V
Sbjct: 249 DEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDV 306
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L A+G+ + F + A+ +G+S ++ K +H SF+ V EEG+EAAA +G+ A
Sbjct: 307 LKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+ V +HPF F IR+ + +ILF GR P
Sbjct: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 188 bits (478), Expect = 6e-48
Identities = 123/392 (31%), Positives = 203/392 (51%), Gaps = 34/392 (8%)
Query: 11 LGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69
L +++ L+ T D NI FSP+ I A+GM+ LG +G+T +E+ HS
Sbjct: 29 LSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQ---KEIRHSMGY------- 78
Query: 70 AEEKEVIENTEAVHQQFQKFLTEISKLT----NDYELNITNRLFGEKTYLFLQKYLDYVE 125
+ ++N E FL E S + + Y + I N LF + + +++L ++
Sbjct: 79 ----DSLKNGEEF-----SFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMK 129
Query: 126 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKG 185
KY++A++ VDF + IN WVE+ TN +KDL ++T L L+N VYFKG
Sbjct: 130 KYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188
Query: 186 QWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQ------AKILGIPYKN 239
W +F+ ENT+ F + + + MM Q F + D ++L IPY+
Sbjct: 189 NWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEG 248
Query: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
+++SM ++L L + + + + EW + ++++KV ++LPRF VE DL+ V
Sbjct: 249 DEISMMLVLSRQEVPLATLEPLVKAQLVEEWAN--SVKKQKVEVYLPRFTVEQEIDLKDV 306
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
L A+G+ + F + A+ +G+S ++ K +H SF+ V EEG+EAAA +G+ A
Sbjct: 307 LKALGITEIFIK-DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365
Query: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
+ V +HPF F IR+ + +ILF GR P
Sbjct: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 187 bits (475), Expect = 1e-47
Identities = 117/381 (30%), Positives = 211/381 (55%), Gaps = 26/381 (6%)
Query: 13 FDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
FDL++ L +IFFSPV I ++ M+ LG +T Q+ E + K+
Sbjct: 50 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQ------KSS 103
Query: 72 EKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHAS 131
EKE+ H+ FQ+ L E+++ + ++L++ N LF + ++ ++ Y A
Sbjct: 104 EKEL-------HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLAD 156
Query: 132 LEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREF 191
P +F ++A + K+IN +V +T KI DL + + S+ +++VN ++FK +W+ F
Sbjct: 157 TFPTNFRDSAG-AMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSF 213
Query: 192 KKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPND 251
+ T+E+ F++ T V MM++ + + +L +++G+PY+ N ++F+ LP++
Sbjct: 214 NHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFI-LPSE 272
Query: 252 IDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSE 311
++++ + +S + L +W ++R++ L+LP+F +E Y LE VL ++G+ + F+
Sbjct: 273 -GKMQQVENGLSEKTLRKWLK--MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTS 329
Query: 312 HKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP-GHENVHCNHPF 370
H AD SG+S+ S + + +H + V V E GT AAAATG FT SA + + N PF
Sbjct: 330 H-ADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPF 388
Query: 371 LFFIRHNESNSILFFGRFSSP 391
L FI N+ILF G+ + P
Sbjct: 389 LMFI---VDNNILFLGKVNRP 406
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 178 bits (452), Expect = 7e-45
Identities = 115/394 (29%), Positives = 210/394 (53%), Gaps = 28/394 (7%)
Query: 4 LGAVSTRLGFDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKE 62
L + + F L+K+L K D N+ FSP+ I TA+ + LG T +++
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEI--------- 99
Query: 63 TKSSRIKAEEKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYL 121
+K + + E +EA +HQ FQ L +++ +++ +L++ N +F ++ L ++
Sbjct: 100 -----LKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFT 154
Query: 122 DYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMV 181
+ ++ Y + DF ++A ++K IN +V++ T KI DL D + S T +VLVN +
Sbjct: 155 EDAKRLYGSEAFATDFQDSA-AAKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYI 211
Query: 182 YFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSH-SFSFTFLEDLQAKILGIPYKNN 240
+FK +W+ F ++T + +F+++K V MM+ H + + E+L ++ + Y N
Sbjct: 212 FFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGN 271
Query: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKV-NLHLPRFEVEDGYDLEAV 299
++F+L D D +E++ + PE L W +E R++ L+LP+F + Y+L +
Sbjct: 272 ASALFIL--PDQDKMEEVEAMLLPETLKRWRD--SLEFREIGELYLPKFSISRDYNLNDI 327
Query: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSA- 358
L +G+ +AF+ KAD SG++ L + +H + + V EEGTEA+AAT + T+ SA
Sbjct: 328 LLQLGIEEAFTS-KADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSAL 386
Query: 359 -PGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
V N PFL I ++ +I F + ++P
Sbjct: 387 VETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 171 bits (434), Expect = 8e-43
Identities = 116/381 (30%), Positives = 204/381 (53%), Gaps = 26/381 (6%)
Query: 13 FDLFKELK-KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
F L+++L ++N NIFFSPV I TA M+ LGT+ T ++ E +
Sbjct: 59 FSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN----------- 107
Query: 72 EKEVIENTEA-VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHA 130
+ E EA +H+ FQ+ L +++ + +L N LF + + K+L+ V+K YH+
Sbjct: 108 ---LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHS 164
Query: 131 SLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 190
V+F + +E++K+IN +VE T KI DL + + T LVN ++FKG+W+R
Sbjct: 165 EAFTVNFGDT-EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERP 221
Query: 191 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPN 250
F+ ++T+EE F +++ T+ V MM + F+ + L + +L + Y N ++F L
Sbjct: 222 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFL--P 279
Query: 251 DIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFS 310
D L+ + ++++ + + ++ + + R +LHLP+ + YDL++VL +G+ FS
Sbjct: 280 DEGKLQHLENELTHDIITKFLE--NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFS 337
Query: 311 EHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPF 370
+ AD SG++ + L K +H + + + E+GTEAA A + S P V N PF
Sbjct: 338 -NGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIP--PEVKFNKPF 394
Query: 371 LFFIRHNESNSILFFGRFSSP 391
+F + + S LF G+ +P
Sbjct: 395 VFLMIEQNTKSPLFMGKVVNP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,575,960
Number of Sequences: 37866
Number of extensions: 575368
Number of successful extensions: 2454
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 2156
Number of HSP's gapped (non-prelim): 141
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.